Msl2 (MSL complex subunit 2) - Rat Genome Database

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Gene: Msl2 (MSL complex subunit 2) Rattus norvegicus
Analyze
Symbol: Msl2
Name: MSL complex subunit 2
RGD ID: 1310355
Description: Predicted to enable histone H2B ubiquitin ligase activity and promoter-enhancer loop anchoring activity. Predicted to be involved in DNA damage response; epigenetic regulation of gene expression; and protein monoubiquitination. Predicted to act upstream of or within positive regulation of DNA-templated transcription. Predicted to be located in chromosome. Predicted to be part of MSL complex. Predicted to be active in chromatin and nucleus. Orthologous to human MSL2 (MSL complex subunit 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase MSL2; LOC108351771; LOC315959; male-specific lethal 2 homolog; male-specific lethal 2 homolog (Drosophila); male-specific lethal 2-like 1; male-specific lethal 2-like 1 (Drosophila); Msl2l1; RGD1310355; similar to KIAA1585 protein; uncharacterized LOC108351771
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88110,555,579 - 110,642,096 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8110,555,271 - 110,647,889 (+)EnsemblGRCr8
mRatBN7.28101,676,605 - 101,702,818 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8101,676,765 - 101,763,833 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8107,339,727 - 107,364,664 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08105,539,044 - 105,563,982 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08103,381,562 - 103,406,501 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08109,456,097 - 109,480,143 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8109,455,786 - 109,478,584 (+)Ensemblrn6Rnor6.0
Rnor_5.08108,872,826 - 108,898,055 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48106,034,690 - 106,059,395 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8101,068,882 - 101,092,934 (+)NCBICelera
RGSC_v3.18106,053,694 - 106,077,241 (+)NCBI
Cytogenetic Map8q31NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (ISO)
chromosome  (IEA)
MSL complex  (IBA,IEA,ISO)
nucleus  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:20018852  


Genomics

Comparative Map Data
Msl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88110,555,579 - 110,642,096 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8110,555,271 - 110,647,889 (+)EnsemblGRCr8
mRatBN7.28101,676,605 - 101,702,818 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8101,676,765 - 101,763,833 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8107,339,727 - 107,364,664 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08105,539,044 - 105,563,982 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08103,381,562 - 103,406,501 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08109,456,097 - 109,480,143 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8109,455,786 - 109,478,584 (+)Ensemblrn6Rnor6.0
Rnor_5.08108,872,826 - 108,898,055 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48106,034,690 - 106,059,395 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8101,068,882 - 101,092,934 (+)NCBICelera
RGSC_v3.18106,053,694 - 106,077,241 (+)NCBI
Cytogenetic Map8q31NCBI
MSL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383136,148,917 - 136,196,335 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3136,148,917 - 136,197,241 (-)Ensemblhg38GRCh38
GRCh373135,867,759 - 135,915,177 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363137,350,450 - 137,397,378 (-)NCBIBuild 36Build 36hg18NCBI36
Build 343137,350,457 - 137,397,386NCBI
Celera3134,293,973 - 134,340,053 (-)NCBICelera
Cytogenetic Map3q22.3NCBI
HuRef3133,245,191 - 133,291,938 (-)NCBIHuRef
CHM1_13135,831,027 - 135,878,223 (-)NCBICHM1_1
T2T-CHM13v2.03138,894,723 - 138,942,140 (-)NCBIT2T-CHM13v2.0
Msl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399100,956,107 - 100,981,999 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9100,956,154 - 100,981,999 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm389101,074,054 - 101,104,800 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9101,074,101 - 101,104,800 (+)Ensemblmm10GRCm38
MGSCv379101,002,900 - 101,007,130 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv379100,978,451 - 100,979,143 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369100,956,680 - 100,964,191 (+)NCBIMGSCv36mm8
Celera9100,614,669 - 100,640,555 (+)NCBICelera
Cytogenetic Map9E4NCBI
cM Map953.17NCBI
Msl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555012,601,424 - 2,645,341 (+)Ensembl
ChiLan1.0NW_0049555012,601,424 - 2,645,341 (+)NCBIChiLan1.0ChiLan1.0
MSL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22134,080,638 - 134,130,979 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13134,084,840 - 134,137,823 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03133,203,579 - 133,252,294 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13140,667,652 - 140,714,924 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3140,667,652 - 140,714,294 (-)EnsemblpanPan2panpan1.1
MSL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12332,629,120 - 32,663,885 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2332,631,804 - 32,664,277 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2332,614,866 - 32,649,754 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02333,158,560 - 33,193,474 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2333,160,078 - 33,191,904 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12332,841,610 - 32,876,769 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02332,909,086 - 32,943,982 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02333,152,766 - 33,187,730 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Msl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560272,274,029 - 72,309,624 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365299,033,895 - 9,068,567 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365299,035,198 - 9,068,567 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MSL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1377,146,318 - 77,180,745 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11377,147,823 - 77,181,410 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21384,517,847 - 84,550,666 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MSL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11554,246,090 - 54,290,809 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1554,246,127 - 54,288,555 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604127,303,470 - 27,351,025 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Msl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473012,569,562 - 12,618,933 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Msl2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1892,442,834 - 92,467,286 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Msl2
937 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:157
Count of miRNA genes:126
Interacting mature miRNAs:137
Transcripts:ENSRNOT00000039593
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)866992095111992095Rat
8693654Alc32Alcohol consumption QTL 3220.755drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)897492344116428905Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)898145073122898010Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
RH127956  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28101,703,579 - 101,703,795 (+)MAPPERmRatBN7.2
Rnor_6.08109,481,420 - 109,481,635NCBIRnor6.0
Rnor_5.08108,898,817 - 108,899,032UniSTSRnor5.0
RGSC_v3.48106,060,157 - 106,060,372UniSTSRGSC3.4
Celera8101,094,211 - 101,094,426UniSTS
RH 3.4 Map81174.4UniSTS
Cytogenetic Map8q31UniSTS
RH140126  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28101,701,648 - 101,701,854 (+)MAPPERmRatBN7.2
Rnor_6.08109,479,489 - 109,479,694NCBIRnor6.0
Rnor_5.08108,896,886 - 108,897,091UniSTSRnor5.0
RGSC_v3.48106,058,226 - 106,058,431UniSTSRGSC3.4
Celera8101,092,280 - 101,092,485UniSTS
RH 3.4 Map81170.9UniSTS
Cytogenetic Map8q31UniSTS
AA956252  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28101,701,007 - 101,701,190 (+)MAPPERmRatBN7.2
Rnor_6.08109,478,848 - 109,479,030NCBIRnor6.0
Rnor_5.08108,896,245 - 108,896,427UniSTSRnor5.0
RGSC_v3.48106,057,585 - 106,057,767UniSTSRGSC3.4
Celera8101,091,639 - 101,091,821UniSTS
RH 3.4 Map81185.1UniSTS
Cytogenetic Map8q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000039593   ⟹   ENSRNOP00000033157
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8110,556,116 - 110,600,265 (+)Ensembl
mRatBN7.2 Ensembl8101,676,765 - 101,763,833 (+)Ensembl
Rnor_6.0 Ensembl8109,455,786 - 109,478,584 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108984   ⟹   ENSRNOP00000097482
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8110,555,271 - 110,647,889 (+)Ensembl
mRatBN7.2 Ensembl8101,676,765 - 101,703,451 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000138467   ⟹   ENSRNOP00000101531
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8110,555,343 - 110,592,091 (+)Ensembl
RefSeq Acc Id: NM_001401885   ⟹   NP_001388814
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88110,556,861 - 110,581,785 (+)NCBI
mRatBN7.28101,677,891 - 101,702,818 (+)NCBI
RefSeq Acc Id: XM_039082584   ⟹   XP_038938512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88110,555,579 - 110,581,272 (+)NCBI
mRatBN7.28101,676,605 - 101,702,818 (+)NCBI
RefSeq Acc Id: XM_039082585   ⟹   XP_038938513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88110,568,457 - 110,581,272 (+)NCBI
mRatBN7.28101,689,485 - 101,702,813 (+)NCBI
RefSeq Acc Id: XM_063265598   ⟹   XP_063121668
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88110,557,239 - 110,614,946 (+)NCBI
RefSeq Acc Id: XM_063265599   ⟹   XP_063121669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88110,557,239 - 110,614,946 (+)NCBI
RefSeq Acc Id: XM_063265600   ⟹   XP_063121670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88110,557,239 - 110,642,096 (+)NCBI
RefSeq Acc Id: XM_063265601   ⟹   XP_063121671
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88110,557,239 - 110,642,096 (+)NCBI
RefSeq Acc Id: XM_063265602   ⟹   XP_063121672
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88110,557,239 - 110,614,946 (+)NCBI
RefSeq Acc Id: XM_063265603   ⟹   XP_063121673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88110,557,239 - 110,642,096 (+)NCBI
RefSeq Acc Id: XM_063265604   ⟹   XP_063121674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88110,557,239 - 110,642,096 (+)NCBI
Ensembl Acc Id: ENSRNOP00000033157   ⟸   ENSRNOT00000039593
RefSeq Acc Id: XP_038938512   ⟸   XM_039082584
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AT15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938513   ⟸   XM_039082585
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AT15 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000097482   ⟸   ENSRNOT00000108984
RefSeq Acc Id: NP_001388814   ⟸   NM_001401885
- UniProtKB: A6I2G4 (UniProtKB/TrEMBL),   A0A8I6AT15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121670   ⟸   XM_063265600
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063121671   ⟸   XM_063265601
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063121673   ⟸   XM_063265603
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063121674   ⟸   XM_063265604
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063121668   ⟸   XM_063265598
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063121669   ⟸   XM_063265599
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063121672   ⟸   XM_063265602
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000101531   ⟸   ENSRNOT00000138467
Protein Domains
CXC MSL2-type   RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A9S3-F1-model_v2 AlphaFold D4A9S3 1-577 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310355 AgrOrtholog
BioCyc Gene G2FUF-29363 BioCyc
Ensembl Genes ENSRNOG00000023021 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000039593.8 UniProtKB/TrEMBL
  ENSRNOT00000108984 ENTREZGENE
  ENSRNOT00000108984.2 UniProtKB/TrEMBL
  ENSRNOT00000138467.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro MSL2 UniProtKB/TrEMBL
  Msl2-CXC UniProtKB/TrEMBL
  Msl2_zf-RING UniProtKB/TrEMBL
  Tesmin/TSO1-like_CXC UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene 315959 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE MSL2 UniProtKB/TrEMBL
  PTHR16048 UniProtKB/TrEMBL
Pfam MSL2-CXC UniProtKB/TrEMBL
  zf-RING_10 UniProtKB/TrEMBL
PhenoGen Msl2 PhenoGen
PROSITE CXC_MSL2 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000023021 RatGTEx
SMART CXC UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A8I6AT15 ENTREZGENE, UniProtKB/TrEMBL
  A6I2G4 ENTREZGENE, UniProtKB/TrEMBL
  D4A9S3_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Msl2  MSL complex subunit 2  LOC108351771  uncharacterized LOC108351771  Data merged from RGD:11485848 737654 PROVISIONAL
2017-06-13 Msl2  MSL complex subunit 2  Msl2  male-specific lethal 2 homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-08-02 LOC108351771  uncharacterized LOC108351771      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-04-23 Msl2  male-specific lethal 2 homolog (Drosophila)  Msl2l1  male-specific lethal 2-like 1 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Msl2l1  male-specific lethal 2-like 1 (Drosophila)   Msl2l1_predicted  male-specific lethal 2-like 1 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Msl2l1_predicted  male-specific lethal 2-like 1 (Drosophila) (predicted)  RGD1310355_predicted  similar to KIAA1585 protein (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1310355_predicted  similar to KIAA1585 protein (predicted)  LOC315959_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC315959_predicted  similar to KIAA1585 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL