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Gene: Hacd4 (3-hydroxyacyl-CoA dehydratase 4) Rattus norvegicus

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Symbol:

Hacd4

Name:

3-hydroxyacyl-CoA dehydratase 4

RGD ID:

1310339

Description:

Predicted to enable enzyme binding activity and very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity. Predicted to be involved in fatty acid elongation; sphingolipid biosynthetic process; and very long-chain fatty acid biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human HACD4 (3-hydroxyacyl-CoA dehydratase 4); INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC362540; protein tyrosine phosphatase-like A domain containing 2; protein tyrosine phosphatase-like protein PTPLAD2; Ptplad2; RGD1310339; similar to RIKEN cDNA 4933428I03; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HACD4 (3-hydroxyacyl-CoA dehydratase 4)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):	Hacd4 (3-hydroxyacyl-CoA dehydratase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Hacd4 (3-hydroxyacyl-CoA dehydratase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HACD4 (3-hydroxyacyl-CoA dehydratase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	HACD4 (3-hydroxyacyl-CoA dehydratase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Hacd4 (3-hydroxyacyl-CoA dehydratase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HACD4 (3-hydroxyacyl-CoA dehydratase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	HACD4 (3-hydroxyacyl-CoA dehydratase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Hacd4 (3-hydroxyacyl-CoA dehydratase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Hacd4 (3-hydroxyacyl-CoA dehydratase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	UMOD (uromodulin)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Hacd4 (3-hydroxyacyl-CoA dehydratase 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Hacd4 (3-hydroxyacyl-CoA dehydratase 4)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	HACD4 (3-hydroxyacyl-CoA dehydratase 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	HACD4 (3-hydroxyacyl-CoA dehydratase 4)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch73-41h24.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	si:ch73-41h24.1	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Hacd2	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	hacd4	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	107,935,514 - 107,961,271 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	107,934,937 - 107,962,836 (-)	Ensembl				GRCr8
mRatBN7.2	5	102,887,597 - 102,915,376 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	102,887,588 - 102,915,338 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	105,251,369 - 105,276,865 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	107,041,826 - 107,067,328 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	107,101,873 - 107,127,890 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	106,728,401 - 106,758,068 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	106,732,513 - 106,758,032 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	110,713,012 - 110,738,726 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	107,706,535 - 107,732,323 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	100,197,158 - 100,222,837 (+)	NCBI		Celera
RGSC_v3.1	5	107,711,760 - 107,737,538 (-)	NCBI
Cytogenetic Map	5	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dichloroethane (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2-palmitoylglycerol (ISO)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3-methylcholanthrene (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (EXP)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

bilirubin IXalpha (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

cisplatin (ISO)

crocidolite asbestos (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

dimethylarsinic acid (EXP)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

fenamidone (ISO)

fenvalerate (EXP)

fluoranthene (ISO)

folic acid (ISO)

gentamycin (EXP)

GSK-J4 (ISO)

hydrogen peroxide (ISO)

indometacin (ISO)

L-methionine (ISO)

lead diacetate (EXP)

methylmercury chloride (ISO)

nickel sulfate (ISO)

nitrates (ISO)

oxaliplatin (EXP)

paracetamol (EXP)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

progesterone (ISO)

rotenone (EXP)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

tetrachloroethene (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trichostatin A (ISO)

triclosan (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

fatty acid biosynthetic process (IEA)

fatty acid elongation (IBA,IEA,ISO)

fatty acid metabolic process (IEA)

lipid metabolic process (IEA)

sphingolipid biosynthetic process (IBA)

very long-chain fatty acid biosynthetic process (IBA,IEA,ISO)

Cellular Component

endoplasmic reticulum (IEA,ISO)

endoplasmic reticulum membrane (IBA,IEA)

membrane (IEA)

Molecular Function

3-hydroxyacyl-CoA dehydratase activity (IBA)

enzyme binding (IEA,ISO)

lyase activity (IEA)

protein binding (ISO)

very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:18554506

Genomics

Comparative Map Data

Hacd4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	107,935,514 - 107,961,271 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	107,934,937 - 107,962,836 (-)	Ensembl				GRCr8
mRatBN7.2	5	102,887,597 - 102,915,376 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	102,887,588 - 102,915,338 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	105,251,369 - 105,276,865 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	107,041,826 - 107,067,328 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	107,101,873 - 107,127,890 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	106,728,401 - 106,758,068 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	106,732,513 - 106,758,032 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	110,713,012 - 110,738,726 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	107,706,535 - 107,732,323 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	100,197,158 - 100,222,837 (+)	NCBI		Celera
RGSC_v3.1	5	107,711,760 - 107,737,538 (-)	NCBI
Cytogenetic Map	5	q32	NCBI

HACD4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	20,999,509 - 21,031,640 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	20,999,509 - 21,031,640 (-)	Ensembl			hg38	GRCh38
GRCh37	9	20,999,508 - 21,031,639 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	20,996,365 - 21,021,635 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	9	20,944,643 - 20,969,914 (-)	NCBI		Celera
Cytogenetic Map	9	p21.3	NCBI
HuRef	9	20,969,219 - 20,994,493 (-)	NCBI		HuRef
CHM1_1	9	21,006,146 - 21,031,415 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	21,013,385 - 21,045,517 (-)	NCBI		T2T-CHM13v2.0

Hacd4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	88,325,924 - 88,357,175 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	88,314,381 - 88,357,165 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	88,407,687 - 88,438,936 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	88,396,144 - 88,438,928 (-)	Ensembl			mm10	GRCm38
MGSCv37	4	88,058,834 - 88,084,830 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	87,884,161 - 87,910,150 (-)	NCBI		MGSCv36	mm8
Celera	4	86,928,616 - 86,954,626 (-)	NCBI		Celera
Cytogenetic Map	4	C4	NCBI
cM Map	4	41.73	NCBI

Hacd4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955434	23,235,928 - 23,261,788 (-)	Ensembl
ChiLan1.0	NW_004955434	23,235,928 - 23,261,288 (-)	NCBI	ChiLan1.0	ChiLan1.0

HACD4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	103,516,228 - 103,543,707 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	103,521,244 - 103,547,140 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	20,811,857 - 20,839,900 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	21,467,332 - 21,495,350 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	21,470,670 - 21,495,350 (-)	Ensembl			panPan2	panpan1.1

HACD4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	40,585,793 - 40,616,232 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	40,586,076 - 40,616,007 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	39,248,297 - 39,278,782 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	41,527,707 - 41,558,197 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	41,527,714 - 41,558,145 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	40,219,861 - 40,250,344 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	40,008,173 - 40,038,644 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	40,643,877 - 40,674,371 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Hacd4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	154,974,131 - 155,007,649 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936652	2,643,712 - 2,677,207 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936652	2,647,639 - 2,677,156 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HACD4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	201,886,332 - 201,910,664 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	201,885,874 - 201,910,667 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	225,505,151 - 225,529,448 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HACD4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1 Ensembl	12	58,754,776 - 58,781,293 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM

Hacd4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624736	25,005,329 - 25,025,611 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624736	25,005,040 - 25,028,163 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Hacd4
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	65,688,026 - 65,713,751 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Hacd4
183 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	221
Count of miRNA genes:	159
Interacting mature miRNAs:	177
Transcripts:	ENSRNOT00000033651
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	102105698	152749382	Rat
1357396	Bw44	Body weight QTL 44	4.19		body mass (VT:0001259)	body weight (CMO:0000012)	5	73779642	118779642	Rat
2303586	Gluco52	Glucose level QTL 52	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	100826632	145826632	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	44924861	153890773	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	38207390	136631402	Rat
1298070	Scl18	Serum cholesterol level QTL 18	3.7		blood LDL cholesterol amount (VT:0000181)	calculated plasma low density lipoprotein cholesterol level (CMO:0001245)	5	84630798	129630798	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	99905133	172190305	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	48523123	134369373	Rat
2302381	Bw84	Body weight QTL 84	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	73779642	118779642	Rat
1357402	Bw46	Body weight QTL 46	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	73779642	118779642	Rat
7411582	Foco3	Food consumption QTL 3	7.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	5	92583776	137583776	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	65089051	166764498	Rat
1598859	Cm66	Cardiac mass QTL 66	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	84630798	129630798	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	51657967	166600247	Rat
1582212	Livw2	Liver weight QTL 2	3.5	0.0004	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	5	104018576	124314782	Rat
7411564	Bw135	Body weight QTL 135		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	92583776	137583776	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	98972960	143972960	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
7411601	Foco12	Food consumption QTL 12	19.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	5	92583776	137583776	Rat
2303618	Vencon1	Ventilatory control QTL 1	3.8		respiration trait (VT:0001943)	oxygen consumption (CMO:0002169)	5	100826632	145826632	Rat
7394708	Emca11	Estrogen-induced mammary cancer QTL 11			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	73176602	118176602	Rat
1598846	Bp293	Blood pressure QTL 293	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	84630798	129630798	Rat
7394710	Emca12	Estrogen-induced mammary cancer QTL 12			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	94034903	139034903	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	69474415	114474415	Rat
1358909	Kidm25	Kidney mass QTL 25	1.87		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	95062526	133270832	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	60601597	137492949	Rat
1600362	Mcs19	Mammary carcinoma susceptibility QTL 19	2.5		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	82032155	127032155	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	74335621	156302135	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	36460764	136631402	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	64589016	109589016	Rat
1298086	Bp156	Blood pressure QTL 156			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	89369373	134369373	Rat
2290005	Mcs24	Mammary carcinoma susceptibility QTL 24			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	69835120	114835120	Rat
2306971	Anxrr21	Anxiety related response QTL 21	9.47		fear/anxiety-related behavior trait (VT:1000241)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	5	70969494	136328156	Rat
1358895	Bp254	Blood pressure QTL 254	3.6	0.0003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	97492524	133270832	Rat
2312671	Scl64	Serum cholesterol level QTL 64		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	73779642	118779642	Rat
1358889	Bp261	Blood pressure QTL 261	2.86		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	95062526	133270832	Rat
6903316	Bw113	Body weight QTL 113	2	0.0103	body mass (VT:0001259)	body weight (CMO:0000012)	5	92881678	137881678	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	104262817	153890625	Rat

Markers in Region

RH132778

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	102,889,671 - 102,889,888 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	106,732,397 - 106,732,613	NCBI	Rnor6.0
Rnor_5.0	5	110,713,067 - 110,713,283	UniSTS	Rnor5.0
RGSC_v3.4	5	107,706,418 - 107,706,635	UniSTS	RGSC3.4
RH 3.4 Map	5	745.9	UniSTS
Cytogenetic Map	5	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108669	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006238376	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008763794	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008763795	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110265	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234476	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000033651 ⟹ ENSRNOP00000034988

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	107,936,955 - 107,961,203 (-)	Ensembl
mRatBN7.2 Ensembl	5	102,891,102 - 102,915,338 (-)	Ensembl
Rnor_6.0 Ensembl	5	106,732,513 - 106,758,032 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101049 ⟹ ENSRNOP00000095794

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	107,935,515 - 107,961,199 (-)	Ensembl
mRatBN7.2 Ensembl	5	102,887,588 - 102,915,338 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000135679 ⟹ ENSRNOP00000110880

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	107,935,515 - 107,962,836 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000139632 ⟹ ENSRNOP00000099570

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	107,934,937 - 107,961,203 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000142010 ⟹ ENSRNOP00000100451

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	107,935,515 - 107,960,446 (-)	Ensembl

RefSeq Acc Id:

NM_001108669 ⟹ NP_001102139

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	107,935,685 - 107,961,203 (-)	NCBI
mRatBN7.2	5	102,889,788 - 102,915,310 (-)	NCBI
Rnor_6.0	5	106,732,513 - 106,758,032 (-)	NCBI
Rnor_5.0	5	110,713,012 - 110,738,726 (-)	NCBI
RGSC_v3.4	5	107,706,535 - 107,732,323 (-)	RGD
Celera	5	100,197,158 - 100,222,837 (+)	RGD

Sequence:

show sequence

AGCCCACTCCTGCTGTTTCTCGGAGGTGCCAGAGAAGCAGACTGTGGCCCATGGGGCCCTCGGT
GCTGCCAGCCTGGCTGCAGCCCAGGTATAGGAAGAGTGCGTATCTTTTCATCTATTACTTAATT
CAGTTCTGTGGCCACTCATGGATACTGACAAACATGACAGTCAGATTCTTCTCATTTGGGAAAG
ATTCAATGGTCGACACGTTTTACGCTATTGGTTTGGTTATGCGGGTTTGCCAATCCATTTCCCT
CTTGGAGTTACTGCACATCTATATTGGCATTGAGTCAAATCAGCTTTTCCCAAAGTTTTTGCAG
CTTACAGAGAGAATTATCATCCTTTTTGGGGTGATCACCAGTCAAGAGGAGGTCCAAGAGAAAT
ATGTAGTGTGTGTTTTATTCATCTTTTGGAATCTACTGGATATGGTAAGGTACACTTACAGCAT
GCTGTCAGTCATAGGGACATCTTATGCTGTCTTGACATGGCTCAGTCAAACACTATGGATGCCA
ATTTACCCTCTGTGTGTTCTTGCTGAAGCATTCACCATCTATCAGTCACTGCCTTACTTTGAGT
TATTTGGCAAAAACTCCACCATGCTTCCGTTTGATATATCTACCTATTTCCCTTACGTGCTGAA
GCTATATCTCATGATGCTCTTCATAGGTATGTATTTTACCTACAGCCATCTTTATACGGAAAGA
AAAGACATCCTCCGAGGATCTTCTGTCAAACAGAAGAAAATGTGAGACAGCCTGTTGCACAGGG
GACAAGATGGGCTGACGGATTAAACTGTAGCGAATACAACACTGGGCCTCTGCTAGAGAAAAAG
AACATAGAACTGGACTGGTCTCCACCATGGCGCCATGTTCCGAAGCTACTGGGCTTTGAGAAAA
GAATTCCCAACAGGTGCAGCGTACACTGCTTTACCAGGGCTGTGGGCGTCATACAAGCTACGTT
TATAATGAGTCGACTCTGAGTGTCTCCCTGTGATGTTAGTGAGAACAGACTCCATGGAGCAAAT
CCAATTGACTTG

hide sequence

RefSeq Acc Id:

XM_006238376 ⟹ XP_006238438

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	107,935,514 - 107,961,271 (-)	NCBI
mRatBN7.2	5	102,887,597 - 102,915,376 (-)	NCBI
Rnor_6.0	5	106,728,401 - 106,758,068 (-)	NCBI
Rnor_5.0	5	110,713,012 - 110,738,726 (-)	NCBI

Sequence:

show sequence

CCGAGCCCAGCCCGAGGCCGCCCCTAGCGCCTTCCCAGCCCACTCCTGCTGTTTCTCGGAGGTG
CCAGAGAAGCAGACTGTGGCCCATGGGGCCCTCGGTGCTGCCAGCCTGGCTGCAGCCCAGGTAT
AGGAAGAGTGCGTATCTTTTCATCTATTACTTAATTCAGTTCTGTGGCCACTCATGGATACTGA
CAAACATGACAGTCAGATTCTTCTCATTTGGGAAAGATTCAATGGTCGACACGTTTTACGCTAT
TGGTTTGGTTATGCGGGTTTGCCAATCCATTTCCCTCTTGGAGTTACTGCACATCTATATTGGC
ATTGAGTCAAATCAGCTTTTCCCAAAGTTTTTGCAGCTTACAGAGAGAATTATCATCCTTTTTG
GGGTGATCACCAGTCAAGAGGAGGTCCAAGAGAAATATGTAGTGTGTGTTTTATTCATCTTTTG
GAATCTACTGGATATGGTAAGGTACACTTACAGCATGCTGTCAGTCATAGGGACATCTTATGCT
GTCTTGACATGGCTCAGTCAAACACTATGGATGCCAATTTACCCTCTGTGTGTTCTTGCTGAAG
CATTCACCATCTATCAGTCACTGCCTTACTTTGAGTTATTTGGCAAAAACTCCACCATGCTTCC
GTTTGATATATCTACCTATTTCCCTTACGTGCTGAAGCTATATCTCATGATGCTCTTCATAGCC
ATCTTTATACGGAAAGAAAAGACATCCTCCGAGGATCTTCTGTCAAACAGAAGAAAATGTGAGA
CAGCCTGTTGCACAGGGGACAAGATGGGCTGACGGATTAAACTGTAGCGAATACAACACTGGGC
CTCTGCTAGAGAAAAAGAACATAGAACTGGACTGGTCTCCACCATGGCGCCATGTTCCGAAGCT
ACTGGGCTTTGAGAAAAGAATTCCCAACAGGTGCAGCGTACACTGCTTTACCAGGGCTGTGGGC
GTCATACAAGCTACGTTTATAATGAGTCGACTCTGAGTGTCTCCCTGTGATGTTAGTGAGAACA
GACTCCATGGAGCAAATCCAATTGACTTGAGAAACCAGCTGATTCACTTCTGCAATAGCAACTA
ACAGACTTATACGAAGGGGATGTGGCAAGATGTCCTCTTGGATTCTAAGATAACATACTCTATA
CACAAATGCCTGTGCCCTTAGAACCGTGAACATTACATATACCCAGAAAATTAAACATCTTCCT
GTACCTTAGCTCAGGTTGCTGCTGTCATAAAATGCACCTCTACCTTATAAAACTTGGTTGTTAA
AACTACAGAAATTTATGTTTTAGGGTTTGGGAGACTTGGAGGTACAAGAGCAAGATGCTCAATG
AGATTAGTGCAGGCGTGGACTATAGACTTGATCAGCCTCTCTAGGAGCACTGCTAGTTTGAGCT
GTAGCTAATAGAGACAGAAAGACAATTAAGACTTCTTAGATTTGACAGAATGCACCCTTGAGCT
TTTTCGGGAGGTGATCGTGCATCACAGGTTACCAGAGGTGTCTCTTCAAATGCATCGGGGCTAC
TTACCAGCTCTGATTTATATGATGATGAGTCCCCTAGGAAAATGGGGGCTTACACTCCAGATGT
TGTTTCTTCCTCATCTCTGATCAAAAGTCACCTTTCCCACACCTGAAAAGGTGCTATGGGCATC
TCCAAAGTCTTTCACCGTCTACTCACTAATGTCACAGCAGCTTCTCCACTTCTATGCTTCGTCC
ATAGCAGTGCCTCACCTTCTGTATCTACTGCTCAATTAGTCTCGATTGTTGCAACAAAGTATTA
TTGAATCGAGTGACTCTGGAAATCAAAAAGCTTAACATCAGGATGCCAAATGACAAGTGGCTTT
TGAGTGTGGGATGAGATGGATGCCTCCTTGCTGGTAGAGAAGGAAAGTACTTCTCCCAGATCTG
TTCTTGTGAACTCACTAATCTCCTCCATAAAGGCTCCCTCTTCATCCCTACTCACTTCCCAAAG
CCCCACCTCCAAGCACTTCCATTCCAAACAAACAAAAAATGTCAACATCTACTAATTCACATCA
TAAAAAGTTATTAGCAGCCTCTTGTTTACTATGGAGCTATATGTTACGACTGAAACATGATTTT
AGATAGTTGCACAGATATGGGAACTGTCCCATATCTGTGCTGTATGTGAACCTTTCTGGTCCAA
TCTGTGCTTGGATACCAGAGGCATAAGGTAGCTTTAACCCTACACTGGTGCACACGCAAAACTA
TCTGTCCTGGCAACTTGTGCTTTCAGAAGCTGACAGAAGATTTGTAACAAAACCCTCCTTTATG
TAGTTACAAACGTGGTCTAAAGAAGTAGCTTCCTGTTTGTGTAAAACATCTTAACAGAACAACT
CACCTCTTACTTGGGGTCACACAGGTAACCAGGAGGGAGGTTATTATTTCAGTGGCAAAGCATT
GAGTTTGGTCTTTAGTGTCACCAATGTAGGCTCTTCAGATGGCCCATAGCCAGAAAACCACATG
ACTTTTCCATACATGACTGCTCAAAACAAAGAACTAGGAAAGAGAGGACTGAGGATCATCTTAT
TTCCTTCTTTCCGTAAACTTCTGTTTTCCTGTGAAGGACAGGAGGAAACACCAGGTTTGAAGAG
AAACTGGGCTGGAAAGACACGAAAAATCTGAAATATGAAGTCTGCACAGATTCTCCCATTCCTC
AGGCATCAGCAAACGCTTGGTTGCTGATTCACAATGAGAAAATGTCTTCGGGGCCCACTTCCTC
TTCTAATCATTGTCTCCTGTGTTTCCAAGGTACTCTGGAATCCAGAGCTCTTTAATGCATGCAG
AAAAACCTGGTCCGCTACAGTACTCTCAAGTTTCCCAGTGCCAAAGGCCTGGTGGTTTTTGTTT
CTTTTTTTTTTTTTTTTTTTGCCTTTTTTTTTAGCAGATGTGCATCTTAAAGTGGGAGCCAAGA
TGTCTGATGCAGTAGAAATAGATAGTTTTGCTCCATTTTAAAGCAGAAAACAGTGTTCCCCATG
GTACTGTTGCAAGACTTCCAACAAGCCAAGCAAAATGAAACATCTAGCGTTTTCACAATCTGGT
CCCCAACAGTAATGCTAGATGACGTTCAGTCTCGAGCTGGTAGGAAATACACAATAGTGCATAT
GGGAAGGAGGAGAAAGCTGGTATAAATTGCTTCTATCTCTTTTCTCTTGGCTTAAACCTGTAAA
AGAGTTATGTATCTGGAAAATAAAACTAGCAGTGCTACTGTGACTTGGTGCACTTTGTGACAAG
AAGATATACTGGACACCTGTGAGTAGCAGAAGTTCCCTGGTGTTTGTGAAAGCCCAGGCACTGT
CTGTGTGGAAGACAAAAGCACCTGACCTCAGTGCCATGACTTTCCCTCCTAACGGTCCCTTGTA
TGTGTATTTATATGACTGGTTGAAGACGGGGCTCAAATCGAAGTCACAATAATCAACAAGCATC
AACATTATAATGTTGCCTGAGTCTCTAGTCATTGCAGGAGCTGAAGTCATGATACTGTCTTTAG
ACCACTAATACTTGAAGCCTTTAGGCCCCTAATATTCTGGTGAAGAGATCTTCAGTCTTATAAA
ACAATTGATCATCTGAGGAGATAGTTATCCATTTCTGTTTGTCTAGCATCCTATCGTCTTCCTC
TCAGGGAAACCCAGTTCAAGTTTGCTTGTGGCTACCTCCTCTGTGTCTAGAACTCAGCTCAACA
CCTGACCTAGGCCTAACCATTGAGTATATCTCACCTGCCAGAGACCAAATACTTCTTAAAAGAC
CTACACGTGTCCCTAGAGTCTGCCCAGTGTTGTGTCTACCATGCCTGTGGGGAAAAGAACCGTT
CTTTATCTTTGACATAGTTACTGGCTGCCATTTTGCTAAGTGGGAGGCATGATCTCCAGAGAAA
GAGACCACAGCATCATAGGATTCATTAGACCAGCCATTGAATTTCTTGGTTTGTGAACTAAGTC
TTCTTTGTGTCCACTGCTGTTGTGAACTGCATAAGTTTCACTTAACTCATGACAACCCAGCATT
GGAATTCTATCTATCACTGATGAATCTAACCTGGGTACCAGTCATTGTCATGCGTAGTGATCAG
GATGTGCCTAGCAGTTCTCTAAGTGGGTGTTTTATCAACAGGAATAAAACTTGTTTAACTCAAT
GACGAGGCTTCATGGAAAGTAGACTATCATATCCTTGTCACCTATATGGTTTACTTTCACTGAC
AAAATCTTCCCACATACTTAAAAATAAGTCACATTGCACAAAACTCATAAGTTTATTTTGCTAG
AACTTAAGGGAGAGAAAATATACTCCAGTTTTCACAAAGAAAAGAAGACTTTTACAATGAATTC
TGGCCATATAGGAGGCATGTTCTATTTCAGTTTCAAATGTCCAGATGCGCAAGGAATGCACCCC
TGGCCACACACATGGTGAGATGTCAGTTTGTAGCCATCTTTTCATGGCCTCCAATGGTGAGGAC
CACGTCTCACTGATCTCAGATAGCAGTCCTAGAAAGCTTCAGTTTCTCTGGTCTGTCTCCTTCA
GTGGAGAATATTGTTGGTTCCTGTGACTGTCACCAGCCATACGCTCGGGTCCATACAGCTTTCT
TCTTAAACTCTGGGAGAACTCTCAAGGACAGCAGGGTGGCTAGGAGGACAAGAACACAGGAAAG
ACTGATACACTTGACAGAGCTGTGCTGTGTCTCAAAAAATCATTTTGATCAAAAAGGTGTCAAA
ACAGTAAATAGGAAAATGTGCAGAACTATTGGTGTTTGGCATGCTAGTGATAATTGTTTTTCTG
AATGTCATTACTATTTACATGAAATGTTGCCTCTTGTAACAATTTACTTTAAATGTGTGTTCTT
TTATACATGAACTGGTTCATCTCCATTAAATATTCAATTAAAAAGAAGCTCCCACCCCTATAAG
AAGGCTGAGTTCTTGTGCTCAATGAAGCAAGTGTACTCATACTAAATTTTACCTGGACATGTAT
CTGTAATGTATGTATTTCCCGTTGTGTTATGGGTCCCAAGGAACAACTAAAGTAGAGAAATTCT
GATTAACACTGTTTAGTAATTACTACATTATATTAATATAATATATTCATAACGTTATGTAAAA
TAAAAGAATGTGAAGGAATATTGGGAACCCAGGCCATTCCAGTAA

hide sequence

RefSeq Acc Id:

XM_039110265 ⟹ XP_038966193

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	107,936,627 - 107,961,271 (-)	NCBI
mRatBN7.2	5	102,890,776 - 102,915,376 (-)	NCBI

RefSeq Acc Id:

XM_063287943 ⟹ XP_063144013

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	107,941,920 - 107,961,271 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102139	(Get FASTA)	NCBI Sequence Viewer
	XP_006238438	(Get FASTA)	NCBI Sequence Viewer
	XP_038966193	(Get FASTA)	NCBI Sequence Viewer
	XP_063144013	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL75999	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000034988
	ENSRNOP00000034988.4
	ENSRNOP00000095794
	ENSRNOP00000095794.2
	ENSRNOP00000099570
	ENSRNOP00000099570.1
	ENSRNOP00000100451.1
	ENSRNOP00000110880.1

RefSeq Acc Id:

NP_001102139 ⟸ NM_001108669

- UniProtKB:

A6KRA5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGPSVLPAWLQPRYRKSAYLFIYYLIQFCGHSWILTNMTVRFFSFGKDSMVDTFYAIGLVMRVC
QSISLLELLHIYIGIESNQLFPKFLQLTERIIILFGVITSQEEVQEKYVVCVLFIFWNLLDMVR
YTYSMLSVIGTSYAVLTWLSQTLWMPIYPLCVLAEAFTIYQSLPYFELFGKNSTMLPFDISTYF
PYVLKLYLMMLFIGMYFTYSHLYTERKDILRGSSVKQKKM

hide sequence

RefSeq Acc Id:	XP_006238438 ⟸ XM_006238376
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AU59 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGPSVLPAWLQPRYRKSAYLFIYYLIQFCGHSWILTNMTVRFFSFGKDSMVDTFYAIGLVMRVC QSISLLELLHIYIGIESNQLFPKFLQLTERIIILFGVITSQEEVQEKYVVCVLFIFWNLLDMVR YTYSMLSVIGTSYAVLTWLSQTLWMPIYPLCVLAEAFTIYQSLPYFELFGKNSTMLPFDISTYF PYVLKLYLMMLFIAIFIRKEKTSSEDLLSNRRKCETACCTGDKMG hide sequence

Ensembl Acc Id:

ENSRNOP00000034988 ⟸ ENSRNOT00000033651

RefSeq Acc Id:	XP_038966193 ⟸ XM_039110265
- Peptide Label:	isoform X2
- UniProtKB:	D3Z8V6 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000095794 ⟸ ENSRNOT00000101049

RefSeq Acc Id:	XP_063144013 ⟸ XM_063287943
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000100451 ⟸ ENSRNOT00000142010

Ensembl Acc Id:

ENSRNOP00000110880 ⟸ ENSRNOT00000135679

Ensembl Acc Id:

ENSRNOP00000099570 ⟸ ENSRNOT00000139632

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3Z8V6-F1-model_v2	AlphaFold	D3Z8V6	1-232	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693829

Promoter ID:

EPDNEW_R4354

Type:

multiple initiation site

Name:

Hacd4_1

Description:

3-hydroxyacyl-CoA dehydratase 4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	106,758,027 - 106,758,087	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310339	AgrOrtholog
BioCyc Gene	G2FUF-40825	BioCyc
BioCyc Pathway	PWY-5080 [very long chain fatty acid biosynthesis I]	BioCyc
	PWY-6598 [sciadonate biosynthesis]	BioCyc
	PWY-7036 [very long chain fatty acid biosynthesis II]	BioCyc
	PWY-7049 [icosapentaenoate biosynthesis II (6-desaturase, mammals)]	BioCyc
	PWY-7592 [arachidonate biosynthesis III (6-desaturase, mammals)]	BioCyc
	PWY-7606 [docosahexaenoate biosynthesis III (6-desaturase, mammals)]	BioCyc
	PWY-7619 [juniperonate biosynthesis]	BioCyc
	PWY-7726 [(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)]	BioCyc
	PWY-8041 [ultra-long-chain fatty acid biosynthesis]	BioCyc
BioCyc Pathway Image	PWY-5080	BioCyc
	PWY-6598	BioCyc
	PWY-7036	BioCyc
	PWY-7049	BioCyc
	PWY-7592	BioCyc
	PWY-7606	BioCyc
	PWY-7619	BioCyc
	PWY-7726	BioCyc
	PWY-8041	BioCyc
Ensembl Genes	ENSRNOG00000005772	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000033651	ENTREZGENE
	ENSRNOT00000033651.7	UniProtKB/TrEMBL
	ENSRNOT00000101049	ENTREZGENE
	ENSRNOT00000101049.2	UniProtKB/TrEMBL
	ENSRNOT00000135679.1	UniProtKB/TrEMBL
	ENSRNOT00000139632	ENTREZGENE
	ENSRNOT00000139632.1	UniProtKB/TrEMBL
	ENSRNOT00000142010.1	UniProtKB/TrEMBL
InterPro	Tyr_Pase-like_PTPLA	UniProtKB/TrEMBL
KEGG Report	rno:362540	UniProtKB/TrEMBL
NCBI Gene	362540	ENTREZGENE
PANTHER	PTPLA	UniProtKB/TrEMBL
	VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 4	UniProtKB/TrEMBL
Pfam	PTPLA	UniProtKB/TrEMBL
PhenoGen	Hacd4	PhenoGen
RatGTEx	ENSRNOG00000005772	RatGTEx
UniProt	A0A8I6AU59	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0KXQ6_RAT	UniProtKB/TrEMBL
	A0ABK0KZ35_RAT	UniProtKB/TrEMBL
	A0ABK0LX08_RAT	UniProtKB/TrEMBL
	A6KRA5	ENTREZGENE, UniProtKB/TrEMBL
	D3Z8V6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-02-04	Hacd4	3-hydroxyacyl-CoA dehydratase 4	Ptplad2	protein tyrosine phosphatase-like A domain containing 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Ptplad2	protein tyrosine phosphatase-like A domain containing 2	Ptplad2_predicted	protein tyrosine phosphatase-like A domain containing 2 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Ptplad2_predicted	protein tyrosine phosphatase-like A domain containing 2 (predicted)	RGD1310339_predicted	similar to RIKEN cDNA 4933428I03 (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1310339_predicted	similar to RIKEN cDNA 4933428I03 (predicted)	LOC362540_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC362540_predicted	similar to RIKEN cDNA 4933428I03 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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