G2e3 (G2/M-phase specific E3 ubiquitin protein ligase) - Rat Genome Database

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Gene: G2e3 (G2/M-phase specific E3 ubiquitin protein ligase) Rattus norvegicus
Analyze
Symbol: G2e3
Name: G2/M-phase specific E3 ubiquitin protein ligase
RGD ID: 1310263
Description: Predicted to enable ubiquitin protein ligase activity. Predicted to act upstream of or within blastocyst development; negative regulation of intrinsic apoptotic signaling pathway; and protein polyubiquitination. Predicted to be located in Golgi apparatus and cytosol. Predicted to be active in nucleus. Orthologous to human G2E3 (G2/M-phase specific E3 ubiquitin protein ligase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: G2/M phase-specific E3 ubiquitin-protein ligase; G2/M-phase specific E3 ubiquitin ligase; LOC299002; RGD1310263; similar to KIAA1333 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8674,498,801 - 74,530,703 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl674,503,109 - 74,528,198 (+)EnsemblGRCr8
mRatBN7.2668,763,847 - 68,795,305 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl668,764,185 - 68,793,924 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx669,199,329 - 69,229,045 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0669,505,985 - 69,535,701 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0668,945,463 - 68,975,179 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0672,092,148 - 72,123,878 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl672,092,194 - 72,122,497 (+)Ensemblrn6Rnor6.0
Rnor_5.0681,655,773 - 81,687,699 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4671,421,049 - 71,451,405 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera667,653,726 - 67,683,695 (+)NCBICelera
RGSC_v3.1671,424,101 - 71,452,823 (+)NCBI
Cytogenetic Map6q22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
coumestrol  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
glycidol  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
hydrogen peroxide  (ISO)
inulin  (ISO)
irinotecan  (ISO)
menadione  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
succimer  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA,ISO)
nucleus  (IBA,IEA)
pericentric heterochromatin  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18511420  


Genomics

Comparative Map Data
G2e3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8674,498,801 - 74,530,703 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl674,503,109 - 74,528,198 (+)EnsemblGRCr8
mRatBN7.2668,763,847 - 68,795,305 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl668,764,185 - 68,793,924 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx669,199,329 - 69,229,045 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0669,505,985 - 69,535,701 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0668,945,463 - 68,975,179 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0672,092,148 - 72,123,878 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl672,092,194 - 72,122,497 (+)Ensemblrn6Rnor6.0
Rnor_5.0681,655,773 - 81,687,699 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4671,421,049 - 71,451,405 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera667,653,726 - 67,683,695 (+)NCBICelera
RGSC_v3.1671,424,101 - 71,452,823 (+)NCBI
Cytogenetic Map6q22NCBI
G2E3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381430,559,158 - 30,620,064 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1430,559,148 - 30,620,064 (+)Ensemblhg38GRCh38
GRCh371431,028,364 - 31,089,270 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361430,098,128 - 30,158,797 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341430,098,127 - 30,158,797NCBI
Celera1410,894,160 - 10,954,826 (+)NCBICelera
Cytogenetic Map14q12NCBI
HuRef1411,145,937 - 11,206,602 (+)NCBIHuRef
CHM1_11431,027,850 - 31,088,578 (+)NCBICHM1_1
T2T-CHM13v2.01424,756,977 - 24,817,883 (+)NCBIT2T-CHM13v2.0
G2e3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391251,395,013 - 51,423,769 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1251,394,844 - 51,423,769 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381251,348,230 - 51,376,986 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1251,348,061 - 51,376,986 (+)Ensemblmm10GRCm38
MGSCv371252,449,217 - 52,477,973 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361252,269,977 - 52,295,391 (+)NCBIMGSCv36mm8
Celera1252,640,648 - 52,669,412 (+)NCBICelera
Cytogenetic Map12B3NCBI
cM Map1222.11NCBI
G2e3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540929,908,148 - 29,945,497 (-)Ensembl
ChiLan1.0NW_00495540929,908,075 - 29,965,331 (-)NCBIChiLan1.0ChiLan1.0
G2E3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21531,890,589 - 31,951,039 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11431,105,788 - 31,167,541 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01411,338,212 - 11,398,545 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11429,482,966 - 29,539,529 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1429,484,584 - 29,539,430 (+)EnsemblpanPan2panpan1.1
G2E3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.189,914,276 - 9,968,798 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl89,914,008 - 9,965,623 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha89,840,612 - 9,892,078 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0810,015,322 - 10,066,847 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl810,015,374 - 10,069,892 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.189,694,186 - 9,748,718 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.089,775,352 - 9,829,972 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0810,051,563 - 10,106,095 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
G2e3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864041,845,996 - 41,903,754 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364945,352,238 - 5,409,739 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364945,352,126 - 5,409,648 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
G2E3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl768,852,777 - 68,916,992 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1768,854,410 - 68,917,070 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2773,481,201 - 73,541,806 (-)NCBISscrofa10.2Sscrofa10.2susScr3
G2E3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl247,415,386 - 7,475,318 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
G2e3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248201,715,455 - 1,774,525 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248201,717,602 - 1,775,175 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
G2e3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1764,778,843 - 64,809,916 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in G2e3
216 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:600
Count of miRNA genes:268
Interacting mature miRNAs:342
Transcripts:ENSRNOT00000005670
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)64451097489510974Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)64095756485957564Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)64515378690153786Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63118500276185002Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)66345744194939581Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)64604735391047353Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)64451097489510974Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)63332884178328841Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)66303731995934232Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)63093763275937632Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)63332884178328841Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63902865986867923Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)64016318385163183Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)66345744194939581Rat

Markers in Region
BI303408  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2668,793,659 - 68,793,844 (+)MAPPERmRatBN7.2
Rnor_6.0672,122,233 - 72,122,417NCBIRnor6.0
Rnor_5.0681,686,056 - 81,686,240UniSTSRnor5.0
RGSC_v3.4671,451,141 - 71,451,325UniSTSRGSC3.4
Celera667,683,431 - 67,683,615UniSTS
RH 3.4 Map6503.2UniSTS
Cytogenetic Map6q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000005670   ⟹   ENSRNOP00000005670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl674,504,563 - 74,528,197 (+)Ensembl
mRatBN7.2 Ensembl668,764,185 - 68,793,924 (+)Ensembl
Rnor_6.0 Ensembl672,092,194 - 72,122,497 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094417   ⟹   ENSRNOP00000079200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl674,504,563 - 74,528,197 (+)Ensembl
mRatBN7.2 Ensembl668,764,185 - 68,793,924 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000122091   ⟹   ENSRNOP00000111434
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl674,503,109 - 74,528,198 (+)Ensembl
RefSeq Acc Id: NM_001106726   ⟹   NP_001100196
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,499,586 - 74,529,322 (+)NCBI
mRatBN7.2668,764,185 - 68,793,924 (+)NCBI
Rnor_6.0672,092,194 - 72,122,497 (+)NCBI
Rnor_5.0681,655,773 - 81,687,699 (+)NCBI
RGSC_v3.4671,421,049 - 71,451,405 (+)RGD
Celera667,653,726 - 67,683,695 (+)RGD
Sequence:
RefSeq Acc Id: XM_006240078   ⟹   XP_006240140
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,498,801 - 74,530,703 (+)NCBI
mRatBN7.2668,763,848 - 68,795,305 (+)NCBI
Rnor_6.0672,092,148 - 72,123,878 (+)NCBI
Rnor_5.0681,655,773 - 81,687,699 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006240079   ⟹   XP_006240141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,498,801 - 74,530,703 (+)NCBI
mRatBN7.2668,764,331 - 68,795,305 (+)NCBI
Rnor_6.0672,095,602 - 72,123,878 (+)NCBI
Rnor_5.0681,655,773 - 81,687,699 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594082   ⟹   XP_017449571
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,498,801 - 74,530,703 (+)NCBI
mRatBN7.2668,763,847 - 68,795,305 (+)NCBI
Rnor_6.0672,092,148 - 72,123,878 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594083   ⟹   XP_017449572
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,498,801 - 74,530,703 (+)NCBI
mRatBN7.2668,764,327 - 68,795,305 (+)NCBI
Rnor_6.0672,095,602 - 72,123,878 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063261666   ⟹   XP_063117736
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,498,801 - 74,530,703 (+)NCBI
RefSeq Acc Id: XM_063261667   ⟹   XP_063117737
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,498,801 - 74,530,703 (+)NCBI
RefSeq Acc Id: NP_001100196   ⟸   NM_001106726
- UniProtKB: D3ZC11 (UniProtKB/TrEMBL),   A6HBG8 (UniProtKB/TrEMBL),   A0A8I5ZML5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240140   ⟸   XM_006240078
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006240141   ⟸   XM_006240079
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017449571   ⟸   XM_017594082
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017449572   ⟸   XM_017594083
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZML5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005670   ⟸   ENSRNOT00000005670
Ensembl Acc Id: ENSRNOP00000079200   ⟸   ENSRNOT00000094417
RefSeq Acc Id: XP_063117736   ⟸   XM_063261666
- Peptide Label: isoform X1
- UniProtKB: A6HBG8 (UniProtKB/TrEMBL),   D3ZC11 (UniProtKB/TrEMBL),   A0A8I5ZML5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117737   ⟸   XM_063261667
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000111434   ⟸   ENSRNOT00000122091
Protein Domains
HECT   PHD-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZC11-F1-model_v2 AlphaFold D3ZC11 1-717 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694582
Promoter ID:EPDNEW_R5107
Type:initiation region
Name:G2e3_1
Description:G2/M-phase specific E3 ubiquitin protein ligase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0672,092,173 - 72,092,233EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310263 AgrOrtholog
BioCyc Gene G2FUF-37597 BioCyc
Ensembl Genes ENSRNOG00000004232 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005670 ENTREZGENE
  ENSRNOT00000005670.9 UniProtKB/TrEMBL
  ENSRNOT00000094417.2 UniProtKB/TrEMBL
  ENSRNOT00000122091 ENTREZGENE
  ENSRNOT00000122091.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Hect, E3 ligase catalytic domain UniProtKB/TrEMBL
  Hect, E3 ligase catalytic domains UniProtKB/TrEMBL
InterPro EPHD UniProtKB/TrEMBL
  HECT UniProtKB/TrEMBL
  Hect_E3_ubiquitin_ligase UniProtKB/TrEMBL
  PHD-type_Zinc_Finger UniProtKB/TrEMBL
  PHF7/G2E3_ePHD UniProtKB/TrEMBL
  PHF7/G2E3_PHD UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report rno:299002 UniProtKB/TrEMBL
NCBI Gene 299002 ENTREZGENE
PANTHER G2/M PHASE-SPECIFIC E3 UBIQUITIN-PROTEIN LIGASE UniProtKB/TrEMBL
  PHD FINGER PROTEIN UniProtKB/TrEMBL
Pfam HECT UniProtKB/TrEMBL
  zf-HC5HC2H UniProtKB/TrEMBL
PhenoGen G2e3 PhenoGen
PROSITE EPHD UniProtKB/TrEMBL
  HECT UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004232 RatGTEx
SMART HECTc UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
Superfamily-SCOP FYVE_PHD_ZnF UniProtKB/TrEMBL
  HECT UniProtKB/TrEMBL
UniProt A0A8I5ZML5 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0M2X2_RAT UniProtKB/TrEMBL
  A6HBG8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZC11 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 G2e3  G2/M-phase specific E3 ubiquitin protein ligase  G2e3  G2/M-phase specific E3 ubiquitin ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-12 G2e3  G2/M-phase specific E3 ubiquitin ligase  RGD1310263  similar to KIAA1333 protein   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1310263  similar to KIAA1333 protein   RGD1310263_predicted  similar to KIAA1333 protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1310263_predicted  similar to KIAA1333 protein (predicted)  LOC299002_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC299002_predicted  similar to KIAA1333 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL