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Gene: Terf2ip (TERF2 interacting protein) Rattus norvegicus

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Symbol:

Terf2ip

Name:

TERF2 interacting protein

RGD ID:

1309684

Description:

Predicted to enable telomeric DNA binding activity. Predicted to be involved in positive regulation of canonical NF-kappaB signal transduction; regulation of nucleobase-containing compound metabolic process; and telomere maintenance. Predicted to be located in chromosome, telomeric region; cytoplasm; and male germ cell nucleus. Predicted to be part of shelterin complex. Orthologous to human TERF2IP (TERF2 interacting protein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC307861; MGC105533; RAP1 homolog; repressor/activator protein 1 homolog; telomeric repeat binding factor 2, interacting protein; telomeric repeat-binding factor 2-interacting protein 1; TERF2-interacting telomeric protein 1; TRF2-interacting telomeric protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TERF2IP (TERF2 interacting protein)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Terf2ip (telomeric repeat binding factor 2, interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Terf2ip (TERF2 interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TERF2IP (TERF2 interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Terf2ip (TERF2 interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TERF2IP (TERF2 interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TERF2IP (TERF2 interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Terf2ip (TERF2 interacting protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TERF2IP (TERF2 interacting protein)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, Panther, PhylomeDB, Treefam
Alliance orthologs ³
Homo sapiens (human):	TERF2IP (TERF2 interacting protein)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TERF2IP (TERF2 interacting protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Terf2ip (telomeric repeat binding factor 2, interacting protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	terf2ip (telomeric repeat binding factor 2, interacting protein)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	RAP1	Alliance	DIOPT (OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	terf2ip	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	56,886,211 - 56,893,300 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	19	56,886,153 - 56,893,392 (+)	Ensembl				GRCr8
mRatBN7.2	19	39,976,965 - 39,984,055 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	39,976,906 - 39,984,064 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	19	46,840,498 - 46,847,586 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	47,493,834 - 47,500,922 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	49,743,110 - 49,750,199 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	44,231,317 - 44,238,406 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	44,231,251 - 44,238,404 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	19	55,037,928 - 55,044,773 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	19	41,946,621 - 41,954,910 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	19	39,337,396 - 39,344,484 (+)	NCBI		Celera
RGSC_v3.1	19	41,951,501 - 41,959,790 (+)	NCBI
Cytogenetic Map	19	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

Aroclor 1254 (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

chlorpyrifos (ISO)

choline (ISO)

Cuprizon (EXP)

epoxiconazole (ISO)

ethanol (ISO)

folic acid (ISO)

gentamycin (EXP)

glafenine (EXP)

L-methionine (ISO)

methimazole (EXP)

nitrates (ISO)

ochratoxin A (EXP)

paracetamol (EXP)

phorone (EXP)

poly(I:C) (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA-templated transcription (IEA)

intracellular signal transduction (IEA)

negative regulation of DNA recombination at telomere (IEA,ISO,ISS)

negative regulation of telomere maintenance (IEA)

positive regulation of canonical NF-kappaB signal transduction (IEA,ISO,ISS)

protection from non-homologous end joining at telomere (IBA,IEA,ISO,ISS)

protein localization to chromosome, telomeric region (IEA)

regulation of DNA-templated transcription (IEA,ISO,ISS)

regulation of double-strand break repair via homologous recombination (IEA,ISO,ISS)

regulation of telomere maintenance (IEA)

telomere capping (IEA)

telomere maintenance (IEA)

telomere maintenance via telomere lengthening (IBA,IEA,ISO,ISS)

telomeric loop formation (ISO)

Cellular Component

chromosome (IEA)

chromosome, telomeric region (IEA,ISO,ISS)

cytoplasm (IEA,ISO,ISS)

nuclear telomere cap complex (IEA)

nucleoplasm (IEA)

nucleus (IEA,ISO,ISS)

shelterin complex (IBA,IEA)

Molecular Function

G-rich strand telomeric DNA binding (IEA)

phosphatase binding (IEA)

protein binding (ISO)

telomeric DNA binding (IBA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:12768206	PMID:14565979	PMID:15100233	PMID:15109494	PMID:15181449	PMID:15383534	PMID:15968270	PMID:16880378	PMID:17055345	PMID:17499040	PMID:17694070	PMID:19135898
PMID:20339076	PMID:20622869	PMID:20622870	PMID:21076401	PMID:21852327	PMID:23178297	PMID:23685356	PMID:23867755	PMID:24062341	PMID:24120135	PMID:24270157	PMID:27050284

Genomics

Comparative Map Data

Terf2ip
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	56,886,211 - 56,893,300 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	19	56,886,153 - 56,893,392 (+)	Ensembl				GRCr8
mRatBN7.2	19	39,976,965 - 39,984,055 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	39,976,906 - 39,984,064 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	19	46,840,498 - 46,847,586 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	47,493,834 - 47,500,922 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	49,743,110 - 49,750,199 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	44,231,317 - 44,238,406 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	44,231,251 - 44,238,404 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	19	55,037,928 - 55,044,773 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	19	41,946,621 - 41,954,910 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	19	39,337,396 - 39,344,484 (+)	NCBI		Celera
RGSC_v3.1	19	41,951,501 - 41,959,790 (+)	NCBI
Cytogenetic Map	19	q12	NCBI

TERF2IP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	75,760,050 - 75,914,672 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	75,647,773 - 75,761,872 (+)	Ensembl			hg38	GRCh38
GRCh37	16	75,681,602 - 75,691,340 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	74,239,185 - 74,248,829 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	16	74,239,184 - 74,248,829	NCBI
Celera	16	59,975,980 - 59,985,684 (+)	NCBI		Celera
Cytogenetic Map	16	q23.1	NCBI
HuRef	16	61,435,312 - 61,445,016 (+)	NCBI		HuRef
CHM1_1	16	77,206,325 - 77,364,191 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	81,808,326 - 81,966,242 (+)	NCBI		T2T-CHM13v2.0

Terf2ip
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	112,737,991 - 112,747,160 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	112,738,030 - 112,747,160 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	112,011,359 - 112,020,528 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	112,011,398 - 112,020,528 (+)	Ensembl			mm10	GRCm38
MGSCv37	8	114,535,259 - 114,544,428 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	114,898,078 - 114,907,132 (+)	NCBI		MGSCv36	mm8
Celera	8	116,240,716 - 116,249,885 (+)	NCBI		Celera
Cytogenetic Map	8	E1	NCBI
cM Map	8	58.29	NCBI

Terf2ip
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955484	1,917,767 - 1,925,044 (-)	Ensembl
ChiLan1.0	NW_004955484	1,917,902 - 1,924,482 (-)	NCBI	ChiLan1.0	ChiLan1.0

TERF2IP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	85,365,677 - 85,375,227 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	91,288,270 - 91,297,800 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	56,216,920 - 56,226,612 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	75,565,090 - 75,574,701 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	75,565,184 - 75,573,882 (+)	Ensembl			panPan2	panpan1.1

Terf2ip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	35,269,446 - 35,276,971 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936475	24,312,101 - 24,320,543 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936475	24,312,140 - 24,319,492 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TERF2IP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	12,014,243 - 12,057,448 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	12,047,409 - 12,057,451 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	11,888,301 - 11,898,336 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TERF2IP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	61,133,028 - 61,142,713 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	61,133,173 - 61,141,896 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666047	14,917,275 - 14,926,965 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Terf2ip
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624746	11,327,467 - 11,337,496 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624746	11,327,473 - 11,337,489 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Terf2ip
11 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	312
Count of miRNA genes:	203
Interacting mature miRNAs:	235
Transcripts:	ENSRNOT00000014660
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61447	Tcas1	Tongue tumor susceptibility QTL 1	6.08		tongue integrity trait (VT:0010553)	squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)	19	19220689	64220689	Rat
724546	Kidm3	Kidney mass QTL 3	3.1		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	19	46226778	74246245	Rat
631840	Niddm38	Non-insulin dependent diabetes mellitus QTL 38	3.86		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	19	10329076	74246245	Rat
7411549	Bw130	Body weight QTL 130	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	32365311	74246245	Rat
724518	Uae19	Urinary albumin excretion QTL 19	5.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	24093973	69093973	Rat
1331737	Uae29	Urinary albumin excretion QTL 29	5.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	36289	74246245	Rat
2303628	Vencon9	Ventilatory control QTL 9		0.005	respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	19	23188586	68188586	Rat
61423	Cia14	Collagen induced arthritis QTL 14	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	19	10833618	74246245	Rat
2313395	Anxrr26	Anxiety related response QTL 26			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	19	44385134	74246245	Rat
1578764	Stresp19	Stress response QTL 19	3.6	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	19	32539615	74246245	Rat
1331788	Rf45	Renal function QTL 45	2.818		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	19	31777888	74246245	Rat
1554318	Bmd5	Bone mineral density QTL 5	12.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	19	23188586	68188586	Rat
2317848	Alcrsp21	Alcohol response QTL 21	1.899999976158142	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	19	20109306	65109306	Rat
1549835	Tcas7	Tongue tumor susceptibility QTL 7		0.001	tongue integrity trait (VT:0010553)	squamous cell carcinoma of the head and neck tumor number (CMO:0001876)	19	41722546	74246245	Rat
7247442	Uae39	Urinary albumin excretion QTL 39			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	2194317	74246245	Rat
724566	Uae12	Urinary albumin excretion QTL 12	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	2194317	74246245	Rat

Markers in Region

RH127771

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	19	39,983,826 - 39,984,015 (+)	MAPPER	mRatBN7.2
Rnor_6.0	19	44,238,178 - 44,238,366	NCBI	Rnor6.0
Rnor_5.0	19	55,044,545 - 55,044,733	UniSTS	Rnor5.0
RGSC_v3.4	19	41,954,682 - 41,954,870	UniSTS	RGSC3.4
Celera	19	39,344,256 - 39,344,444	UniSTS
RH 3.4 Map	19	516.6	UniSTS
Cytogenetic Map	19	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013143	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC117869	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC090335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227595	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000014660 ⟹ ENSRNOP00000014660

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	19	56,886,153 - 56,893,392 (+)	Ensembl
mRatBN7.2 Ensembl	19	39,976,906 - 39,984,064 (+)	Ensembl
Rnor_6.0 Ensembl	19	44,231,251 - 44,238,404 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114583 ⟹ ENSRNOP00000085839

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	19	39,976,926 - 39,984,052 (+)	Ensembl

RefSeq Acc Id:

NM_001013143 ⟹ NP_001013161

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	56,886,211 - 56,893,300 (+)	NCBI
mRatBN7.2	19	39,976,965 - 39,984,055 (+)	NCBI
Rnor_6.0	19	44,231,317 - 44,238,406 (+)	NCBI
Rnor_5.0	19	55,037,928 - 55,044,773 (+)	NCBI
RGSC_v3.4	19	41,946,621 - 41,954,910 (+)	RGD
Celera	19	39,337,396 - 39,344,484 (+)	RGD

Sequence:

show sequence

GTCTTCTCAGTGTTGTCCCTTTGCTTTTCTTGGGCAGCGGAGCGACAGGTATGGCGGAGGTAAT
GGATCTGGGTAAAGATCCCAATGGGCCCACCCACTCCTCCACTCTGTTTGTGAGAGAAGACGGC
AGCGCCATGTCGTTTTACGTGCGGCCCAGCTCGGCCAAGCGCCGGCTGTCAACGCTCATCCTGC
ACGGCGGCGGCATCTTGTGTCGGGTGCAGAAGCCCGGGGCGGTGCTGCTAGCCCAGCCCGGGGA
GGCGCTGGCCGAGGCTTCGGGCGACTTCATCTCCACGCAGTACATCCTAGACTGCGTGGAGCGC
AACGAGAAGCTGGAACTGGAGGCCTATCGGCTGGGCCTGACGGAGCAGGCGTCCGACCCTAAGC
CCGGGGCTTCTGCGGAGGGCTCCACGGAACCCGAGCCTCAGCCCCTGACCGGGCGCATTGCCTA
CACTGACGCAGACGATGTGGCCATCCTAACCTACGTAAAGGAAAATGCCCGTTCGCCCAGCTCA
GTCACAGGCAATGCCTTGTGGAAAGCGATGGAGAAGAGCTCGCTCACGCAGCACTCCTGGCAGT
CGCTCAAGGACCGCTACCTCAAGCACCTGCAGGGCCAGGAGCACAAGTACCTGCTCGGGAACGC
TCCGGTCAGCCCGTCCTCCCAGAAGCTCAAACGGAAGGCGGAGCAGGACCCGGAGGCTGCGGAT
AGCGGGGAGCCACAGAACAAGAGGACGCCAGACTTGCCTGAAGAGGAGTGTGTGAAGGGGGAGA
CCAAGGAGAATGGAGAGGCAGACAACAAGCTATTTGAGGAAGCTACTCCGGAGTTGGGGGAAGC
CGTGGTGGATGAGAGCCCTGACTTTGAAATACACATAACCATGTGTGATGGTGATCCACCCACA
CCTGAGGAAGATTCAGAAACACAGCCAGACGAGGAGGAAGAGGAACCAAAAGTTTCTACACAAG
AAGTGGGAACTGCCATTAAGATCATCCGGCAGCTAATGGAAAAGTTTAACTTGGATCTCTCAAC
AGTTACACAGGCCTTGCTGAAAAACAGTGGTGAACTGGAGGCCACTTCCTCTTTCTTAGAGTCT
GGACGGAGACCTGATGGTTTCCCAATTTGGTGCCGACAAGATGACTTAGATTTGCAAAAGGACG
ATGATGACACTAGAAATGCACTGGTCAAAAAATATGGAGCTCAGAATGTTGCTCGGAGGATCGA
ATTTCGAAAGAAATAAGGACAAGATAACCAAGACAGGTGACCATGTAAGCATCTTGTGACCATT
GAAGCTGACGGGTGCTGCCGCTCTGTGAACCCCAGGTTTTGTAGCCAAGCAGTATAATGTAGCA
GGATAAAACAAAAGAAACTGGATTAGAGCTGTCGGTGGCCAGTATCCCATGTTTATGATAGGCA
AATCTAAGCCAGAGAGGTTGGTCTGTGTAGTAGTGAGCCTTGGTTGGAATGTGGCTCCCATTGT
ACAGGAGACAGCAGCCAAGTGACAAAGTCAAGATTAGAAATGAAAGGAAACTTGATTGGTGAGT
GAATAACCTTCTGTCTTCTGGCAGAAATTGCTTTAGGTGGAGGGTCCCAAACCAAAAGTCTAGA
AGTAAGATTTAATTGTAGAGCTTATACATGGACTGTCCCAAACTATCCCATTCCCCAGGGAGCT
CTGGGCTCTGTTTCGATGGTGTTGAATTATCCCACAGGCATCTTGCTAACAGTCTTTGAAATCT
CCTCTCCTTCCGTGGCTCTTGCTGTTTGAGTTTTGAATCAAGTCTCTATAGCATGTATTTGGTT
ACTTACCATCCACTCTGTGTACACGAAGCCCTAGGCCTGGGGGAGCTTCCACCCTTTCCAACAT
AAAAGATGTCATATACAGACTTCACAGTCAGGAATCAAAGAGAAAATCAAGTTATAGACACACG
CACAGATCTTAAAGCTCTGTGCTGTAAGTTTGTGATTCTGTGTTTCACCCTTGTCGCTATCCTC
AGACAAGGTAGGTTGGAGACTCTTAATTGTGATATGTTTGTAAATTTTATGGAACGTAAGTTTT
CTGCTGAAAATTATGTAGACTTAAAATTTAGTTGATTGGTCCACTTTGTTGTGTTGTTTTTGTC
ATTGAAAATAAATATAATTTTGTGTTTGAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001013161	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH90335	(Get FASTA)	NCBI Sequence Viewer
	EDL92603	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000014660
	ENSRNOP00000085839.1
GenBank Protein	Q5EAN7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001013161 ⟸ NM_001013143

- UniProtKB:

Q5EAN7 (UniProtKB/Swiss-Prot), A6IZC5 (UniProtKB/TrEMBL), A0A8L2Q715 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAEVMDLGKDPNGPTHSSTLFVREDGSAMSFYVRPSSAKRRLSTLILHGGGILCRVQKPGAVLL
AQPGEALAEASGDFISTQYILDCVERNEKLELEAYRLGLTEQASDPKPGASAEGSTEPEPQPLT
GRIAYTDADDVAILTYVKENARSPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLQGQEHKY
LLGNAPVSPSSQKLKRKAEQDPEAADSGEPQNKRTPDLPEEECVKGETKENGEADNKLFEEATP
ELGEAVVDESPDFEIHITMCDGDPPTPEEDSETQPDEEEEEPKVSTQEVGTAIKIIRQLMEKFN
LDLSTVTQALLKNSGELEATSSFLESGRRPDGFPIWCRQDDLDLQKDDDDTRNALVKKYGAQNV
ARRIEFRKK

hide sequence

Ensembl Acc Id:

ENSRNOP00000014660 ⟸ ENSRNOT00000014660

Ensembl Acc Id:

ENSRNOP00000085839 ⟸ ENSRNOT00000114583

Protein Domains

BRCT Myb-like TERF2-interacting telomeric protein 1 Myb TRF2-interacting telomeric protein/Rap1 C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5EAN7-F1-model_v2	AlphaFold	Q5EAN7	1-393	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701159

Promoter ID:

EPDNEW_R11683

Type:

initiation region

Name:

Terf2ip_1

Description:

TERF2 interacting protein

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	19	44,231,289 - 44,231,349	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309684	AgrOrtholog
BioCyc Gene	G2FUF-5633	BioCyc
Ensembl Genes	ENSRNOG00000010712	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000014660	ENTREZGENE
	ENSRNOT00000114583.1	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.10.2170	UniProtKB/Swiss-Prot
	Homeodomain-like	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7302641	IMAGE-MGC_LOAD
InterPro	BRCT_dom	UniProtKB/Swiss-Prot
	Homeobox-like_sf	UniProtKB/Swiss-Prot
	Rap1_C	UniProtKB/Swiss-Prot
	Rap1_C_sf	UniProtKB/Swiss-Prot
	Rap1_Myb_dom	UniProtKB/Swiss-Prot
	TE2IP/Rap1	UniProtKB/Swiss-Prot
KEGG Report	rno:307861	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105533	IMAGE-MGC_LOAD
NCBI Gene	307861	ENTREZGENE
PANTHER	PTHR16466	UniProtKB/Swiss-Prot
	TELOMERIC REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1	UniProtKB/Swiss-Prot
Pfam	BRCT_2	UniProtKB/Swiss-Prot
	Myb_DNA-bind_2	UniProtKB/Swiss-Prot
	Rap1_C	UniProtKB/Swiss-Prot
PhenoGen	Terf2ip	PhenoGen
RatGTEx	ENSRNOG00000010712	RatGTEx
Superfamily-SCOP	SSF46689	UniProtKB/Swiss-Prot
UniProt	A0A8L2Q715	ENTREZGENE, UniProtKB/TrEMBL
	A6IZC5	ENTREZGENE, UniProtKB/TrEMBL
	Q5EAN7	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-01	Terf2ip	TERF2 interacting protein	Terf2ip	telomeric repeat binding factor 2, interacting protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Terf2ip	telomeric repeat binding factor 2, interacting protein	Terf2ip_predicted	telomeric repeat binding factor 2, interacting protein (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Terf2ip_predicted	telomeric repeat binding factor 2, interacting protein (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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