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Gene: Cmtr2 (cap methyltransferase 2) Rattus norvegicus

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Symbol:

Cmtr2

Name:

cap methyltransferase 2

RGD ID:

1309394

Description:

Predicted to enable methyltransferase cap1 activity and methyltransferase cap2 activity. Predicted to be involved in 7-methylguanosine mRNA capping. Predicted to be active in cytoplasm and nucleus. Orthologous to human CMTR2 (cap methyltransferase 2); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2; FtsJ methyltransferase domain containing 1; ftsJ methyltransferase domain-containing protein 1; Ftsjd1; LOC292016; RGD1309394; similar to adrift CG5032-PA

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CMTR2 (cap methyltransferase 2)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Cmtr2 (cap methyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cmtr2 (cap methyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CMTR2 (cap methyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CMTR2 (cap methyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cmtr2 (cap methyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CMTR2 (cap methyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CMTR2 (cap methyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cmtr2 (cap methyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Cmtr2 (cap methyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Cmtr2 (cap methyltransferase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	CMTR2 (cap methyltransferase 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	CMTR2 (cap methyltransferase 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cmtr2 (cap methyltransferase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y40D12A.1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	aft	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cmtr2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	55,100,135 - 55,106,966 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	19	55,099,843 - 55,124,234 (+)	Ensembl				GRCr8
mRatBN7.2	19	38,190,718 - 38,197,549 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	38,190,642 - 38,197,804 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	19	44,997,390 - 45,004,221 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	45,650,747 - 45,657,578 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	47,960,297 - 47,967,128 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	41,426,536 - 41,433,367 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	41,427,504 - 41,433,346 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	19	52,255,039 - 52,261,870 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	19	40,102,287 - 40,109,118 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	19	37,586,767 - 37,593,598 (+)	NCBI		Celera
RGSC_v3.1	19	40,110,577 - 40,112,911 (+)	NCBI
Cytogenetic Map	19	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adenoid cystic carcinoma (ISO)

lung adenocarcinoma (ISO)

polycystic ovary syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,1,1-trichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

amphetamine (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

dioxygen (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

fluoranthene (ISO)

formaldehyde (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

paracetamol (EXP,ISO)

quercetin (ISO)

quinolin-8-ol (ISO)

rotenone (ISO)

sunitinib (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

7-methylguanosine mRNA capping (IBA,IEA,ISO)

methylation (IEA)

mRNA processing (IEA)

Cellular Component

cytoplasm (IBA,IEA,ISO)

nucleus (IBA,IEA,ISO)

Molecular Function

methyltransferase activity (IEA)

methyltransferase cap1 activity (IBA,IEA)

methyltransferase cap2 activity (IEA,ISO)

transferase activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:21310715

Genomics

Comparative Map Data

Cmtr2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	55,100,135 - 55,106,966 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	19	55,099,843 - 55,124,234 (+)	Ensembl				GRCr8
mRatBN7.2	19	38,190,718 - 38,197,549 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	38,190,642 - 38,197,804 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	19	44,997,390 - 45,004,221 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	45,650,747 - 45,657,578 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	47,960,297 - 47,967,128 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	41,426,536 - 41,433,367 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	41,427,504 - 41,433,346 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	19	52,255,039 - 52,261,870 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	19	40,102,287 - 40,109,118 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	19	37,586,767 - 37,593,598 (+)	NCBI		Celera
RGSC_v3.1	19	40,110,577 - 40,112,911 (+)	NCBI
Cytogenetic Map	19	q12	NCBI

CMTR2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	71,281,392 - 71,289,722 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	71,281,389 - 71,289,715 (-)	Ensembl			hg38	GRCh38
GRCh37	16	71,315,295 - 71,323,625 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	69,873,704 - 69,881,010 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	16	55,626,986 - 55,634,292 (-)	NCBI		Celera
Cytogenetic Map	16	q22.2	NCBI
HuRef	16	57,079,722 - 57,087,029 (-)	NCBI		HuRef
CHM1_1	16	72,723,423 - 72,730,729 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	77,092,514 - 77,100,845 (-)	NCBI		T2T-CHM13v2.0

Cmtr2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	110,941,977 - 110,951,121 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	110,942,297 - 110,951,118 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	110,215,346 - 110,224,489 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	110,215,665 - 110,224,486 (+)	Ensembl			mm10	GRCm38
MGSCv37	8	112,741,860 - 112,748,389 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	113,107,118 - 113,113,615 (+)	NCBI		MGSCv36	mm8
Celera	8	114,441,479 - 114,448,008 (+)	NCBI		Celera
Cytogenetic Map	8	D3	NCBI
cM Map	8	57.48	NCBI

Cmtr2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955484	3,999,665 - 4,006,632 (-)	Ensembl
ChiLan1.0	NW_004955484	3,999,655 - 4,006,632 (-)	NCBI	ChiLan1.0	ChiLan1.0

CMTR2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	82,875,858 - 82,883,131 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	88,809,492 - 88,816,770 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	53,727,087 - 53,734,555 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	71,114,691 - 71,121,996 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

CMTR2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	77,117,795 - 77,124,995 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	77,118,964 - 77,121,264 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	77,079,720 - 77,086,960 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	77,556,583 - 77,563,818 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	77,554,670 - 77,563,755 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	77,377,086 - 77,384,331 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	77,199,985 - 77,207,209 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	77,699,053 - 77,706,292 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Cmtr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	37,127,738 - 37,155,123 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936475	22,434,180 - 22,440,846 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936475	22,434,009 - 22,441,350 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CMTR2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	14,323,981 - 14,334,008 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	14,325,869 - 14,334,043 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

CMTR2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	54,428,889 - 54,435,770 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	54,430,197 - 54,432,509 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666047	17,237,214 - 17,244,543 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cmtr2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624746	13,475,816 - 13,484,046 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624746	13,475,463 - 13,484,063 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Cmtr2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	17	29,921,737 - 29,928,644 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Cmtr2
68 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	424
Count of miRNA genes:	222
Interacting mature miRNAs:	271
Transcripts:	ENSRNOT00000022952
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61447	Tcas1	Tongue tumor susceptibility QTL 1	6.08		tongue integrity trait (VT:0010553)	squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)	19	19220689	64220689	Rat
724546	Kidm3	Kidney mass QTL 3	3.1		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	19	46226778	74246245	Rat
631840	Niddm38	Non-insulin dependent diabetes mellitus QTL 38	3.86		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	19	10329076	74246245	Rat
7411549	Bw130	Body weight QTL 130	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	32365311	74246245	Rat
724518	Uae19	Urinary albumin excretion QTL 19	5.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	24093973	69093973	Rat
1331737	Uae29	Urinary albumin excretion QTL 29	5.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	36289	74246245	Rat
2303628	Vencon9	Ventilatory control QTL 9		0.005	respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	19	23188586	68188586	Rat
61423	Cia14	Collagen induced arthritis QTL 14	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	19	10833618	74246245	Rat
2313395	Anxrr26	Anxiety related response QTL 26			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	19	44385134	74246245	Rat
1578764	Stresp19	Stress response QTL 19	3.6	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	19	32539615	74246245	Rat
1331788	Rf45	Renal function QTL 45	2.818		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	19	31777888	74246245	Rat
1554318	Bmd5	Bone mineral density QTL 5	12.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	19	23188586	68188586	Rat
2317848	Alcrsp21	Alcohol response QTL 21	1.899999976158142	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	19	20109306	65109306	Rat
1549835	Tcas7	Tongue tumor susceptibility QTL 7		0.001	tongue integrity trait (VT:0010553)	squamous cell carcinoma of the head and neck tumor number (CMO:0001876)	19	41722546	74246245	Rat
7247442	Uae39	Urinary albumin excretion QTL 39			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	2194317	74246245	Rat
724566	Uae12	Urinary albumin excretion QTL 12	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	2194317	74246245	Rat

Markers in Region

D19Rat10

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	19	55,107,208 - 55,107,440 (+)	Marker Load Pipeline
mRatBN7.2	19	38,197,791 - 38,198,023 (-)	MAPPER	mRatBN7.2
Rnor_6.0	19	41,426,062 - 41,426,293	NCBI	Rnor6.0
Rnor_5.0	19	52,254,565 - 52,254,796	UniSTS	Rnor5.0
RGSC_v3.4	19	40,109,361 - 40,109,741	UniSTS	RGSC3.4
Celera	19	37,593,841 - 37,594,076	UniSTS
RH 3.4 Map	19	462.7	UniSTS
RH 3.4 Map	19	462.7	RGD
RH 2.0 Map	19	517.5	RGD
SHRSP x BN Map	19	27.9098	RGD
FHH x ACI Map	19	30.2099	RGD
Cytogenetic Map	19	q12	UniSTS

BE102253

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	19	38,197,378 - 38,197,550 (-)	MAPPER	mRatBN7.2
Rnor_6.0	19	41,426,535 - 41,426,706	NCBI	Rnor6.0
Rnor_5.0	19	52,255,038 - 52,255,209	UniSTS	Rnor5.0
RGSC_v3.4	19	40,108,948 - 40,109,119	UniSTS	RGSC3.4
Celera	19	37,593,428 - 37,593,599	UniSTS
RH 3.4 Map	19	462.8	UniSTS
Cytogenetic Map	19	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	355	192	11	143	80	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106186	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000022952 ⟹ ENSRNOP00000022952

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	19	55,099,843 - 55,107,897 (+)	Ensembl
mRatBN7.2 Ensembl	19	38,190,642 - 38,197,804 (+)	Ensembl
Rnor_6.0 Ensembl	19	41,427,504 - 41,433,346 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000149139 ⟹ ENSRNOP00000110089

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	19	55,100,052 - 55,124,234 (+)	Ensembl

RefSeq Acc Id:

NM_001106186 ⟹ NP_001099656

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	55,100,135 - 55,106,966 (+)	NCBI
mRatBN7.2	19	38,190,718 - 38,197,549 (+)	NCBI
Rnor_6.0	19	41,426,536 - 41,433,367 (-)	NCBI
Rnor_5.0	19	52,255,039 - 52,261,870 (-)	NCBI
RGSC_v3.4	19	40,102,287 - 40,109,118 (+)	RGD
Celera	19	37,586,767 - 37,593,598 (+)	RGD

Sequence:

show sequence

GAAGCTGTTCCCGGGAGCGGAAGTAGCGGGTGGCTCGCTAGCGTGAGTGAGGACCGCGTGTACC
GTGCTACTGCTCCAGCCCGTGCGGCTCTGGTGGGCGTGGGCTGGAGGAATGCGGACCCGACTTC
TCGGTTTTTAACTTGGTCTGAAAATGAGCAAGCGCAGGAAGCGTCCAGCTCAGCAGCCAGCGAG
CCCCGAGACCTTCAGCCCAGACGCTCTCAATGCCGTGTCTGAGCTCTTCGCCAAGAACTTTTCC
TACTGTAAGCCACTCGATCACGAGTGGCAGTTACCAGCTCCCGCCGAGAGCTTCACCTGCGAGC
ACGTCGAGTTCCAAGCTTTCCTTGACTTGAAGAACTCCCTGAACGCAGTGAAAAACCTCCTGTG
CGATAAGGAGCTGGACGGCTGGCACAGGCACACCGCCTTCACCAACAGGGCGGGGCAGATCATC
GCCCACGTGAGAAAGGCCGTGAACGCAGAACTCTGTACTCAGGCCTGGTGCAAGTTCCAGGAGA
TCTTGTGCAGTTTCCCACTTATCCCGCAGGAAGCTTTTCAGAGTGGAAGACTGAATTCTCTGCA
CCTGTGTGAAGCCCCAGGCGCTTTCATAGCCAGCCTCAACCATTACTTAAAATCCCACCGGTTC
CCCTGTGAATGGAGCTGGGTAGCAAATAGCCTGAACCCATACCACGAGGCCAACGACAATCTTA
GGATGATTACGGACGACCGGCTGATTGCAAACACCTTGCACCGCTGGTACTTCGGCCCAGATAA
CACTGGTGATATCATGACCCTGAAGTACCTGACCGGGCTTCAGGACTTCCTCAGCGGCACATCT
CCCATTCACTTGGTCACTGCTGATGGGAGTTTTGACTGCCAGGGAAACCCAGGCGAACAGGAAG
CTTTAGTCTCCCCTTTGCATTACTGTGAAGCTGTCACTGCTCTGACCACCCTTGGAGATGGTGG
CTCTTTTGTTCTAAAGATGTTTACGTTGTTTGAACACTGTTCTGTGAACCTCATGTACCTGCTA
AATTGTTCCTTTGACCAAGTTCACGTTTTCAAACCTGCTACTAGCAAGGCGGGAAACTCAGAAG
TCTACGTGGTGTGTCTCTGCTATAAGGGAAGAGAGGCTATTCGTCCTTTGCTATCTAGGATGGT
GTTGAACTTTGGCACTGAGATGACCAAGAAGGCGCTCTTTCCCCATCATGTGATCCCCAAATCC
TTTCTTGAGCGACACAGAGAGTGTTGTACACTCTTCCATAGATACCAGTTAGAGACTATCTCTG
AGAACATTCGTCTTTTTGAGTGCATGGGGACGGGGGAGCAAGAGAAACTGAATAACTTAAGGAA
CTGTGCTGTACAGCATTTTATGCAAAAGTTCCAACTGAAGCCCCTTTCTAGAAATCACTGGCTC
GTCAAAAAATCCACTCTTGGCTGCAGTACAAACACAAAATGGTTCGGACAGAGAAACAAGTATT
TTAGAACCTATAACGAACGGAAGATGCTGGAAACCCTTTCGTGGAAGGATAAAGTAGCCAGGGG
ATTCTTCGATAGTTGGGCGGAGGAACATGTCGTCTATCACCCCGGGCAGAGCCCCCTCCTAGAA
GGGAGTGCTTCCAGCCTCGAGTGCCACTTGTGGTGCATTCTAGAAGGCAAGAAACTGCCGAAGG
TGAAGTGTTCTCCTTTCTGTGATAGTGAAATTTTAAAGACTCTTAATGAAGCCATTGAGAAGTC
CTCAGGAGAAGCTTTGAGTGTGGAGTCCAAGGTCAGTCCCAAGCAGCAATACCGCTGTTGCCAA
ATCTTCTCGGAAGAATCGGTGTTATCCGAGTTGCTGAGCCTTACCAAGTGCCTTCAGGAAGAGC
AGGGTGTAGAACCCAGCAACCCCATCAGGTGCCTGCTTGTGGGTTCACCCACTGTCCGCGATCT
CCAAATGTACACGGCCCTGGAAGTCCAGCTTCTGGAGTCCGTCGAACTTACTGCCTTCAGCTGT
TCACTGCTCCATGACGGTGACCCCGCCTACCAACATTTGTTTTTGAATTGCCTGCTACACTCCC
TGAAGCAGCTTCACTCGGGAGATGTGATGATTTTGCCCATCCTTTCCTGCTTCACAAGGTTTAT
GGCTGGCTTGACCTTTGTCCTCCACAGCTGTTTTAGATTTATCACATTCTCTTGTCCCACATCG
TCTGAGCCCCTCAGGACCTGTGCTGTCCTGCTATGCATTGGTTATCAGAACCTTCCAGATCCAG
TTTTTCAGTTTCTGCAGAACGTTAACGAACTCTTGGGCACTTTGCTCCACCCCGGTGCCCCCCA
GCAGGTTTTACAGTTTGTACCAATGGAGGTGCTCCTTCAGGGGACACTGCTTGATTTTTTGTGG
GATCTGAATGCTGCCATTGCTAAAAGGCATTTGCATTTGATTATCCAAGGAGAGAGAGACAAAG
TCATCAGCAGCCTCGAGTTGTAAAATTGAACATGGCGTTGTTGATGTGTCGTTTTGCAACTTAA
CACTTTGATTCCATTTTACCTGCCCTATTTATTTAATAATTTTCATCTTGGAGAAATGCCAGTT
TGTGTATTAAAGGACATTAATTATGGAAAGTCATAGCTTGTTCTGATCAGAAGGACATAGGACT
GGTAGGTACAGCGTTTTTGTGGTAGGAACCATGCTCTGATGGTGTCCAGCCTCTAATCATGTGA
CATCCGTGTGTGCTCGGGGTGACTACACGCTTGCTTGCATATGCAGCTGAGCTGGTCTTATCCA
GCCTAGCACCGTGTGCCTTCATCCAGACATCATCCCCCCACTGATTCCTCTCTGTCTGATGCTG
TTAATGGTGAGGTTAGTCATGACAGGAGGTGAGTCACTCTTGGCCACCGCTCTTTACCTGGAAA
CACTTGACACATCTGGATTTCAGGGATCTCTATACCAGGTTTCTTGATAAGTGCCGTTCCCTGC
TTTTAGATTGATGGTTCGGTTTTCTTTGAATTGATGTGAAATACGGAGTTTTTGTGTGACTTTT
TGCGAGCTATAAGTATCCAACCAATCAAGCCAAAACCAAAGGTCATTTCTGTACAGTGAAGATT
GTGTCTAGCACTCCTTTGTTGTGAAAAGCTTCCTTCAGCAATGTTGGCATTTTCATTGTCCTGG
AAAGATGGTTCTAAGGCTCGTGTAAAGTCTCCTGTGGGTGACAGCAGAGTGCGGTGGTCACGGA
GAACACTTGAGGGAAATGTAACACTTCCAGAATGACAGCTGGACACATTGTTAATCTTTGCCGT
TTATTTTTTTCAGTACGAAAATAGCACTTTACTAAGATTATCCGTGAGATAGATATTTTATCAA
TTTTATTTGATTTTGTTGAGTAATATATATTTAATAATATAGTGAACTTTTCTAGCAACAGGTT
AATTCTTCATCACTTTAAAGTTTTTAGATGTCATGTAAATGTTTAGGTATTTTCTGTTCCTTAA
AAACATAGAAGTATTCTGCCATGTATCCAGTTAATAAATTTTTCATGCTCTTCTATTTTTGAGT
TCCATTACAATTCACAAATAAAGCCTTCAGCAG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001099656	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL92534	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000022952
	ENSRNOP00000022952.3
	ENSRNOP00000110089.1

RefSeq Acc Id:

NP_001099656 ⟸ NM_001106186

- UniProtKB:

D3Z980 (UniProtKB/TrEMBL), A6IZ56 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSKRRKRPAQQPASPETFSPDALNAVSELFAKNFSYCKPLDHEWQLPAPAESFTCEHVEFQAFL
DLKNSLNAVKNLLCDKELDGWHRHTAFTNRAGQIIAHVRKAVNAELCTQAWCKFQEILCSFPLI
PQEAFQSGRLNSLHLCEAPGAFIASLNHYLKSHRFPCEWSWVANSLNPYHEANDNLRMITDDRL
IANTLHRWYFGPDNTGDIMTLKYLTGLQDFLSGTSPIHLVTADGSFDCQGNPGEQEALVSPLHY
CEAVTALTTLGDGGSFVLKMFTLFEHCSVNLMYLLNCSFDQVHVFKPATSKAGNSEVYVVCLCY
KGREAIRPLLSRMVLNFGTEMTKKALFPHHVIPKSFLERHRECCTLFHRYQLETISENIRLFEC
MGTGEQEKLNNLRNCAVQHFMQKFQLKPLSRNHWLVKKSTLGCSTNTKWFGQRNKYFRTYNERK
MLETLSWKDKVARGFFDSWAEEHVVYHPGQSPLLEGSASSLECHLWCILEGKKLPKVKCSPFCD
SEILKTLNEAIEKSSGEALSVESKVSPKQQYRCCQIFSEESVLSELLSLTKCLQEEQGVEPSNP
IRCLLVGSPTVRDLQMYTALEVQLLESVELTAFSCSLLHDGDPAYQHLFLNCLLHSLKQLHSGD
VMILPILSCFTRFMAGLTFVLHSCFRFITFSCPTSSEPLRTCAVLLCIGYQNLPDPVFQFLQNV
NELLGTLLHPGAPQQVLQFVPMEVLLQGTLLDFLWDLNAAIAKRHLHLIIQGERDKVISSLEL

hide sequence

Ensembl Acc Id:

ENSRNOP00000022952 ⟸ ENSRNOT00000022952

Ensembl Acc Id:

ENSRNOP00000110089 ⟸ ENSRNOT00000149139

Protein Domains

Adrift-type SAM-dependent 2'-O-MTase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3Z980-F1-model_v2	AlphaFold	D3Z980	1-767	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701128

Promoter ID:

EPDNEW_R11652

Type:

multiple initiation site

Name:

Cmtr2_1

Description:

cap methyltransferase 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	19	41,433,340 - 41,433,400	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309394	AgrOrtholog
BioCyc Gene	G2FUF-5692	BioCyc
Ensembl Genes	ENSRNOG00000017102	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000022952	ENTREZGENE
	ENSRNOT00000022952.7	UniProtKB/TrEMBL
	ENSRNOT00000149139.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.12760	UniProtKB/TrEMBL
InterPro	Adrift_MeTrfase	UniProtKB/TrEMBL
	mRNA_Cap_2O-Ribose_MeTrfase	UniProtKB/TrEMBL
	rRNA_MeTrfase_RrmJ/FtsJ	UniProtKB/TrEMBL
	SAM-dependent_MTases-like	UniProtKB/TrEMBL
KEGG Report	rno:292016	UniProtKB/TrEMBL
NCBI Gene	292016	ENTREZGENE
PANTHER	CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 2	UniProtKB/TrEMBL
	UNCHARACTERIZED	UniProtKB/TrEMBL
Pfam	FtsJ	UniProtKB/TrEMBL
PhenoGen	Cmtr2	PhenoGen
PROSITE	SAM_MT_ADRIFT	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000017102	RatGTEx
Superfamily-SCOP	SSF53335	UniProtKB/TrEMBL
UniProt	A6IZ56	ENTREZGENE, UniProtKB/TrEMBL
	D3Z980	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-08-01	Cmtr2	cap methyltransferase 2	Ftsjd1	FtsJ methyltransferase domain containing 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-09	Ftsjd1	FtsJ methyltransferase domain containing 1	RGD1309394	similar to adrift CG5032-PA	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1309394	similar to adrift CG5032-PA	RGD1309394_predicted	similar to adrift CG5032-PA (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-20	RGD1309394_predicted	similar to adrift CG5032-PA (predicted)	LOC292016_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC292016_predicted	similar to adrift CG5032-PA (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD