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Gene: Dgcr6 (DiGeorge syndrome critical region gene 6) Rattus norvegicus

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Symbol:

Dgcr6

Name:

DiGeorge syndrome critical region gene 6

RGD ID:

1309390

Description:

Orthologous to human DGCR6 (DiGeorge syndrome critical region gene 6) and DGCR6L (DiGeorge syndrome critical region gene 6 like); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acrylamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC303794

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DGCR6 (DiGeorge syndrome critical region gene 6)	HGNC	EggNOG, Ensembl, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Dgcr6 (DiGeorge syndrome critical region gene 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DGCR6 (DiGeorge syndrome critical region gene 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DGCR6 (DiGeorge syndrome critical region gene 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	DGCR6L (DiGeorge syndrome critical region gene 6 like)	HGNC	Ensembl, Inparanoid, OrthoDB, Panther, PhylomeDB, Treefam
Homo sapiens (human):	CRYBB1 (crystallin beta B1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	DGCR6 (DiGeorge syndrome critical region gene 6)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	DGCR6 (DiGeorge syndrome critical region gene 6)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Dgcr6 (DiGeorge syndrome critical region gene 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	DGCR6L (DiGeorge syndrome critical region gene 6 like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	dgcr6 (DiGeorge syndrome critical region gene 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	gdl	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	itln1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	dgcr6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	dgcr6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	96,432,024 - 96,442,766 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	96,432,024 - 96,437,255 (-)	Ensembl				GRCr8
mRatBN7.2	11	82,927,725 - 82,932,823 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	82,927,725 - 82,932,823 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	91,656,101 - 91,661,137 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	84,317,219 - 84,322,255 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	83,370,836 - 83,375,872 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	11	98,295,743 - 98,300,783 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	11	96,492,452 - 96,497,497 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	11	97,416,391 - 97,421,431 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	11	96,222,340 - 96,227,385 (-)	NCBI		F344_StmMcwi
Rnor_6.0	11	87,076,205 - 87,081,306 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	87,076,381 - 87,081,950 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	90,168,058 - 90,173,154 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	84,922,649 - 84,927,694 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	81,703,405 - 81,708,450 (-)	NCBI		Celera
RGSC_v3.1	11	84,963,245 - 84,968,334 (-)	NCBI
Cytogenetic Map	11	q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

DiGeorge syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17alpha-ethynylestradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (EXP)

acrylamide (EXP,ISO)

amitrole (EXP)

amphetamine (EXP)

arsane (ISO)

arsenic atom (ISO)

benzatropine (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

butan-1-ol (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

clozapine (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

Cuprizon (ISO)

dibutyl phthalate (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

fenthion (ISO)

gentamycin (EXP)

kainic acid (ISO)

lead diacetate (ISO)

lipopolysaccharide (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methotrexate (ISO)

ochratoxin A (ISO)

paracetamol (EXP,ISO)

perfluorononanoic acid (ISO)

perfluorooctanoic acid (ISO)

pirinixic acid (ISO)

selenium atom (ISO)

sodium arsenite (ISO)

Soman (EXP)

sunitinib (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

triclosan (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Dgcr6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	96,432,024 - 96,442,766 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	96,432,024 - 96,437,255 (-)	Ensembl				GRCr8
mRatBN7.2	11	82,927,725 - 82,932,823 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	82,927,725 - 82,932,823 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	91,656,101 - 91,661,137 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	84,317,219 - 84,322,255 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	83,370,836 - 83,375,872 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	11	98,295,743 - 98,300,783 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	11	96,492,452 - 96,497,497 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	11	97,416,391 - 97,421,431 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	11	96,222,340 - 96,227,385 (-)	NCBI		F344_StmMcwi
Rnor_6.0	11	87,076,205 - 87,081,306 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	87,076,381 - 87,081,950 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	90,168,058 - 90,173,154 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	84,922,649 - 84,927,694 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	81,703,405 - 81,708,450 (-)	NCBI		Celera
RGSC_v3.1	11	84,963,245 - 84,968,334 (-)	NCBI
Cytogenetic Map	11	q23	NCBI

DGCR6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	18,906,223 - 18,912,088 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	18,905,677 - 18,914,281 (+)	Ensembl			hg38	GRCh38
GRCh37	22	18,893,833 - 18,899,601 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	17,273,779 - 17,279,601 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	22	17,268,345 - 17,274,146	NCBI
Celera	22	2,745,929 - 2,751,791 (+)	NCBI		Celera
Cytogenetic Map	22	q11.21	NCBI
HuRef	22	2,515,964 - 2,521,863 (+)	NCBI		HuRef
CHM1_1	22	18,893,495 - 18,899,360 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	22	19,281,581 - 19,287,480 (+)	NCBI		T2T-CHM13v2.0

Dgcr6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	17,870,736 - 17,889,497 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	17,870,724 - 17,889,496 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	16	18,052,860 - 18,071,633 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	18,052,860 - 18,071,632 (+)	Ensembl			mm10	GRCm38
MGSCv37	16	18,052,953 - 18,071,435 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	16	17,966,423 - 17,984,905 (+)	NCBI		MGSCv36	mm8
Celera	16	18,625,430 - 18,643,927 (+)	NCBI		Celera
Cytogenetic Map	16	A3	NCBI
cM Map	16	11.19	NCBI

DGCR6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	28,531,539 - 28,538,834 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	31,080,221 - 31,086,535 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	1,647,018 - 1,653,326 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	17,348,556 - 17,350,597 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2

DGCR6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	5,418,938 - 5,424,585 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666100	964,021 - 969,821 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	69
Count of miRNA genes:	56
Interacting mature miRNAs:	62
Transcripts:	ENSRNOT00000002574
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10450831	Scl80	Serum cholesterol level QTL 80	4.7	0.01	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	11	90461781	96556255	Rat
10058954	Gmadr7	Adrenal mass QTL 7	2.49	0.0049	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	73850894	99753367	Rat
4889859	Pur28	Proteinuria QTL 28	19.5	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	11	58928336	99753367	Rat
724561	Plsm4	Polydactyly-luxate syndrome (PLS) morphotypes QTL 4		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	11	67962184	99753367	Rat
631506	Bp104	Blood pressure QTL 104	2.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	73308315	99753367	Rat
4889521	Gluco62	Glucose level QTL 62	2.82	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	68599321	96497754	Rat
7411658	Foco27	Food consumption QTL 27	16.2	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	11	69855943	99753367	Rat
1549848	Bvd6	Brain ventricular dilatation QTL 6	3.1	0.0001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	11	79618519	99753367	Rat

Markers in Region

Dgcr6

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	82,927,925 - 82,929,587 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	87,076,406 - 87,078,067	NCBI	Rnor6.0
Rnor_5.0	11	90,168,259 - 90,169,920	UniSTS	Rnor5.0
RGSC_v3.4	11	84,922,850 - 84,924,511	UniSTS	RGSC3.4
Celera	11	81,703,606 - 81,705,267	UniSTS
Cytogenetic Map	11	q23	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
10	16	12	150	245	91	90	65	139	59	22	485	331	11	224	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006248609	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063270459	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063270460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063270461	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC158828	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000002574 ⟹ ENSRNOP00000002574

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	96,432,024 - 96,437,097 (-)	Ensembl
mRatBN7.2 Ensembl	11	82,927,728 - 82,932,823 (-)	Ensembl
Rnor_6.0 Ensembl	11	87,076,381 - 87,081,950 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000102550 ⟹ ENSRNOP00000096660

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	11	96,432,024 - 96,437,255 (-)	Ensembl
mRatBN7.2 Ensembl	11	82,927,725 - 82,932,757 (-)	Ensembl

RefSeq Acc Id:

NM_001107080 ⟹ NP_001100550

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	96,432,024 - 96,437,069 (-)	NCBI
mRatBN7.2	11	82,927,725 - 82,932,770 (-)	NCBI
Dahl_SR_JrHsd	11	98,295,743 - 98,300,783 (-)	NCBI
Lyon_Normotensive	11	96,492,452 - 96,497,497 (-)	NCBI
Lyon_Hypertensive	11	97,416,391 - 97,421,431 (-)	NCBI
F344_StmMcwi	11	96,222,340 - 96,227,385 (-)	NCBI
Rnor_6.0	11	87,076,205 - 87,081,250 (-)	NCBI
Rnor_5.0	11	90,168,058 - 90,173,154 (-)	NCBI
RGSC_v3.4	11	84,922,649 - 84,927,694 (-)	RGD
Celera	11	81,703,405 - 81,708,450 (-)	RGD

Sequence:

show sequence

GGGGGGCCGCGCTATGGACCGCTATGCGGGCGCCGGGGACGAGGCGGCGGACCGGGCCCGGCAG
CAGGAGCGGCACTACCAGCTGCTGTCAGCGCTACAGAGCCTGGTCAAGGAACTGCCCAGCTCTT
TTCAGCAGCGCCTGTCCTACACCACGCTCAGCGACTTAGCCCTGGCGCTGCTCGACGGAACGGT
GTTTGAGATCGTACAGGGGCTTCTGGAGATCCAGCACCTCACCGAGAAGAGCCTCTACAACCAA
CGACTGCGGCTGCAGAACGAACACAGAGTGCTCAGACAGACTCTGAGGCAAAAGCATCTGGAAG
CCCAGCAGTCCTGCCGGCCCCACAACTTGCCAGTGCTCCAGGCAGCCCAGCAGCGTGAGCTAGA
GGCCTTGGAACACCGGATCCGGGAGGAGCAGCAGGCAATGGACCGAAAGATTGTCCTGGAGCTG
GACCGGAAGGTTGCTGACCAGCAGAGCACACTGGAGAAGGCAGGGGTAGCTGGTTTCTATGTGA
CCACTAATCCTCAGGAGCTGACGCTGCAGATGAACTTACTGGAACTCATCAGGAAGCTGCAACA
GAGGGGCTGCCAAATGGGAAAGCCGGCTCTGTGACCAAGTGGGCGGTCCTCGCTGTCCTCTGTT
GCCTAGGATGGCTGGCACCACAGCCTTGTCTGTGTGGGGGCTACTGACTGTCCGGCTGCCAACA
GGCCTGATCTCTCTGAGGAGCTGACTAGACCCTGGCTATGCCCGCTGCCACCCACTGATCAGAT
TTGGAGGGGAAGGTCCAAGCAATAGGAATGGTGTCATGAGAAGGCCCCATGACTGAATGCTGAG
TGGGAATGTGGGTCCCTCTGGGCATATCCCTCCAGGCTTGGGCTTTGCCTTGTTCCTGTGTAGC
ACCTCCCTTGACAGCCCCCACCCTCGGTGGAAGAAGCTACAAAACCCAAGCCCAGTATGGCCTA
GAAAAATAAAGAACCCAGGACGTGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAA

hide sequence

RefSeq Acc Id:

XM_006248609 ⟹ XP_006248671

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	96,432,024 - 96,442,766 (-)	NCBI
mRatBN7.2	11	82,927,725 - 82,932,823 (-)	NCBI
Rnor_6.0	11	87,076,205 - 87,081,306 (-)	NCBI
Rnor_5.0	11	90,168,058 - 90,173,154 (-)	NCBI

Sequence:

show sequence

GCTGGAGAATGACGTAAGGGGGCGGGACACACTAAGAGACAGACTCGAGGGGCGGCGGGGGGCC
GCGCTATGGACCGCTATGCGGGCGCCGGGGACGAGGCGGCGGACCGGGCCCGGCAGCAGGAGCG
GCACTACCAGCTGCTGTCAGCGCTACAGAGCCTGGTCAAGGAACTGCCCAGCTCTTTTCAGCAG
CGCCTGTCCTACACCACGCTCAGCGACTTAGCCCTGGCGCTGCTCGACGGAACGGTGTTTGAGA
TCGTACAGGGGCTTCTGGAGATCCAGCACCTCACCGAGAAGAGCCTCTACAACCAACGACTGCG
GCTGCAGAACGAACACAGAGTGCTCAGACAGACTCTGAGGCAAAAGCATCTGGAAGCCCAGCAG
TCCTGCCGGCCCCACAACTTGCCAGTGCTCCAGGCAGCCCAGCAGCGTGAGCTAGAGCCCTGGC
AGGCCTTGGAACACCGGATCCGGGAGGAGCAGCAGGCAATGGACCGAAAGATTGTCCTGGAGCT
GGACCGGAAGGTTGCTGACCAGCAGAGCACACTGGAGAAGGCAGGGGTAGCTGGTTTCTATGTG
ACCACTAATCCTCAGGAGCTGACGCTGCAGATGAACTTACTGGAACTCATCAGGAAGCTGCAAC
AGAGGGGCTGCCAAATGGGAAAGCCGGCTCTGTGACCAAGTGGGCGGTCCTCGCTGTCCTCTGT
TGCCTAGGATGGCTGGCACCACAGCCTTGTCTGTGTGGGGGCTACTGACTGTCCGGCTGCCAAC
AGGCCTGATCTCTCTGAGGAGCTGACTAGACCCTGGCTATGCCCGCTGCCACCCACTGATCAGA
TTTGGAGGGGAAGGTCCAAGCAATAGGAATGGTGTCATGAGAAGGCCCCATGACTGAATGCTGA
GTGGGAATGTGGGTCCCTCTGGGCATATCCCTCCAGGCTTGGGCTTTGCCTTGTTCCTGTGTAG
CACCTCCCTTGACAGCCCCCACCCTCGGTGGAAGAAGCTACAAAACCCAAGCCCAGTATGGCCT
AGAAAAATAAAGAACCCAGGACGTGG

hide sequence

RefSeq Acc Id:

XM_063270459 ⟹ XP_063126529

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	96,432,024 - 96,437,129 (-)	NCBI

RefSeq Acc Id:

XM_063270460 ⟹ XP_063126530

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	96,433,247 - 96,437,129 (-)	NCBI

RefSeq Acc Id:

XM_063270461 ⟹ XP_063126531

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	96,433,936 - 96,437,122 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100550	(Get FASTA)	NCBI Sequence Viewer
	XP_006248671	(Get FASTA)	NCBI Sequence Viewer
	XP_063126529	(Get FASTA)	NCBI Sequence Viewer
	XP_063126530	(Get FASTA)	NCBI Sequence Viewer
	XP_063126531	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI58829	(Get FASTA)	NCBI Sequence Viewer
	EDL77916	(Get FASTA)	NCBI Sequence Viewer
	EDL77917	(Get FASTA)	NCBI Sequence Viewer
	EDL77918	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000002574
	ENSRNOP00000002574.5
	ENSRNOP00000096660
	ENSRNOP00000096660.1

RefSeq Acc Id:

NP_001100550 ⟸ NM_001107080

- UniProtKB:

B0BNH6 (UniProtKB/TrEMBL), A6JSJ1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDRYAGAGDEAADRARQQERHYQLLSALQSLVKELPSSFQQRLSYTTLSDLALALLDGTVFEIV
QGLLEIQHLTEKSLYNQRLRLQNEHRVLRQTLRQKHLEAQQSCRPHNLPVLQAAQQRELEALEH
RIREEQQAMDRKIVLELDRKVADQQSTLEKAGVAGFYVTTNPQELTLQMNLLELIRKLQQRGCQ
MGKPAL

hide sequence

RefSeq Acc Id:	XP_006248671 ⟸ XM_006248609
- Peptide Label:	isoform X1
- UniProtKB:	F7FP83 (UniProtKB/TrEMBL), A0A8I6AQQ6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDRYAGAGDEAADRARQQERHYQLLSALQSLVKELPSSFQQRLSYTTLSDLALALLDGTVFEIV QGLLEIQHLTEKSLYNQRLRLQNEHRVLRQTLRQKHLEAQQSCRPHNLPVLQAAQQRELEPWQA LEHRIREEQQAMDRKIVLELDRKVADQQSTLEKAGVAGFYVTTNPQELTLQMNLLELIRKLQQR GCQMGKPAL hide sequence

Ensembl Acc Id:

ENSRNOP00000002574 ⟸ ENSRNOT00000002574

Ensembl Acc Id:

ENSRNOP00000096660 ⟸ ENSRNOT00000102550

RefSeq Acc Id:	XP_063126529 ⟸ XM_063270459
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063126530 ⟸ XM_063270460
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_063126531 ⟸ XM_063270461
- Peptide Label:	isoform X4

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B0BNH6-F1-model_v2	AlphaFold	B0BNH6	1-198	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698311

Promoter ID:

EPDNEW_R8836

Type:

multiple initiation site

Name:

Dgcr6_1

Description:

DiGeorge syndrome critical region gene 6

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	11	87,081,278 - 87,081,338	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309390	AgrOrtholog
BioCyc Gene	G2FUF-20633	BioCyc
Ensembl Genes	ENSRNOG00000001880	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000002574	ENTREZGENE
	ENSRNOT00000002574.8	UniProtKB/TrEMBL
	ENSRNOT00000102550	ENTREZGENE
	ENSRNOT00000102550.2	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7378165	IMAGE-MGC_LOAD
InterPro	DGCR6	UniProtKB/TrEMBL
KEGG Report	rno:303794	UniProtKB/TrEMBL
MGC_CLONE	MGC:188273	IMAGE-MGC_LOAD
NCBI Gene	303794	ENTREZGENE
PANTHER	DGCR6	UniProtKB/TrEMBL
	PROTEIN DGCR6	UniProtKB/TrEMBL
Pfam	DGCR6	UniProtKB/TrEMBL
PhenoGen	Dgcr6	PhenoGen
RatGTEx	ENSRNOG00000001880	RatGTEx
UniProt	A0A8I6AQQ6	ENTREZGENE, UniProtKB/TrEMBL
	A6JSJ1	ENTREZGENE, UniProtKB/TrEMBL
	B0BNH6	ENTREZGENE, UniProtKB/TrEMBL
	F7FP83	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Dgcr6	DiGeorge syndrome critical region gene 6	Dgcr6_predicted	DiGeorge syndrome critical region gene 6 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Dgcr6_predicted	DiGeorge syndrome critical region gene 6 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD