Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Anks1a | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Anks1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ANKS1 mRNA | CTD | PMID:36331819 | Anks1a | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Anks1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANKS1 mRNA | CTD | PMID:22206623 | Anks1a | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Anks1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ANKS1 mRNA | CTD | PMID:17942748 | Anks1a | Rat | 17beta-estradiol | decreases expression | ISO | Anks1 (Mus musculus) | 6480464 | Estradiol results in decreased expression of ANKS1 mRNA | CTD | PMID:39298647 | Anks1a | Rat | 17beta-estradiol | increases expression | ISO | ANKS1A (Homo sapiens) | 6480464 | Estradiol results in increased expression of ANKS1A mRNA | CTD | PMID:31614463 | Anks1a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Anks1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ANKS1 mRNA | CTD | PMID:17942748 | Anks1a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Anks1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ANKS1 mRNA | CTD | PMID:15328365 | Anks1a | Rat | 2-methylcholine | affects expression | ISO | ANKS1A (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of ANKS1A mRNA | CTD | PMID:21179406 | Anks1a | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | ANKS1A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Anks1a | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Anks1 (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of ANKS1 mRNA | CTD | PMID:18648102 | Anks1a | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | ANKS1A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Anks1a | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Anks1 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of ANKS1 exon | CTD | PMID:33297965 | Anks1a | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Anks1 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of ANKS1 mRNA | CTD | PMID:39298647 | Anks1a | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of ANKS1A mRNA | CTD | PMID:24780913 | Anks1a | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of ANKS1A mRNA | CTD | PMID:30047161 | Anks1a | Rat | aconitine | decreases expression | EXP | | 6480464 | Aconitine results in decreased expression of ANKS1A protein | CTD | PMID:33236894 | Anks1a | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of ANKS1A mRNA | CTD | PMID:30047161 | Anks1a | Rat | antirheumatic drug | increases expression | ISO | ANKS1A (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of ANKS1A mRNA | CTD | PMID:24449571 | Anks1a | Rat | arsenite(3-) | multiple interactions | ISO | ANKS1A (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to ANKS1A mRNA] | CTD | PMID:32406909 | Anks1a | Rat | arsenous acid | multiple interactions | ISO | ANKS1A (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ANKS1A protein] | CTD | PMID:26598702 | Anks1a | Rat | benzo[a]pyrene | multiple interactions | ISO | Anks1 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of ANKS1 mRNA] | CTD | PMID:22228805 | Anks1a | Rat | benzo[a]pyrene | decreases expression | ISO | ANKS1A (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ANKS1A mRNA | CTD | PMID:20064835|PMID:20106945|PMID:21632981 | Anks1a | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | ANKS1A (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ANKS1A mRNA | CTD | PMID:19150397 | Anks1a | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | ANKS1A (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of ANKS1A mRNA | CTD | PMID:31163220 | Anks1a | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of ANKS1A mRNA | CTD | PMID:25181051 | Anks1a | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ANKS1A mRNA | CTD | PMID:30816183 | Anks1a | Rat | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of ANKS1A mRNA | CTD | PMID:19167457 | Anks1a | Rat | cadmium atom | multiple interactions | ISO | Anks1 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which affects the expression of ANKS1 mRNA | CTD | PMID:28111341 | Anks1a | Rat | cadmium dichloride | multiple interactions | ISO | Anks1 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which affects the expression of ANKS1 mRNA | CTD | PMID:28111341 | Anks1a | Rat | caffeine | affects phosphorylation | ISO | ANKS1A (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of ANKS1A protein | CTD | PMID:35688186 | Anks1a | Rat | carbon nanotube | decreases expression | ISO | Anks1 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of ANKS1 mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681 | Anks1a | Rat | CGP 52608 | multiple interactions | ISO | ANKS1A (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ANKS1A gene] | CTD | PMID:28238834 | Anks1a | Rat | chlorpyrifos | increases expression | ISO | Anks1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of ANKS1 mRNA | CTD | PMID:37019170 | Anks1a | Rat | cisplatin | decreases expression | ISO | ANKS1A (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of ANKS1A mRNA | CTD | PMID:27594783 | Anks1a | Rat | clofibrate | decreases expression | ISO | Anks1 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of ANKS1 mRNA | CTD | PMID:23811191 | Anks1a | Rat | coumarin | affects phosphorylation | ISO | ANKS1A (Homo sapiens) | 6480464 | coumarin affects the phosphorylation of ANKS1A protein | CTD | PMID:35688186 | Anks1a | Rat | cytarabine | decreases expression | ISO | ANKS1A (Homo sapiens) | 6480464 | Cytarabine results in decreased expression of ANKS1A mRNA | CTD | PMID:21198554 | Anks1a | Rat | dexamethasone | multiple interactions | ISO | ANKS1A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Anks1a | Rat | diarsenic trioxide | multiple interactions | ISO | ANKS1A (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ANKS1A protein] | CTD | PMID:26598702 | Anks1a | Rat | dicrotophos | increases expression | ISO | ANKS1A (Homo sapiens) | 6480464 | dicrotophos results in increased expression of ANKS1A mRNA | CTD | PMID:28302478 | Anks1a | Rat | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of ANKS1A mRNA | CTD | PMID:21551480 | Anks1a | Rat | enzyme inhibitor | multiple interactions | ISO | ANKS1A (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Anks1a | Rat | epoxiconazole | decreases expression | ISO | Anks1 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of ANKS1 mRNA | CTD | PMID:35436446 | Anks1a | Rat | folic acid | multiple interactions | ISO | Anks1 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANKS1 mRNA | CTD | PMID:22206623 | Anks1a | Rat | FR900359 | affects phosphorylation | ISO | ANKS1A (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of ANKS1A protein | CTD | PMID:37730182 | Anks1a | Rat | hydrogen peroxide | affects expression | ISO | ANKS1A (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of ANKS1A mRNA | CTD | PMID:21179406 | Anks1a | Rat | indometacin | multiple interactions | ISO | ANKS1A (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] more ... | CTD | PMID:28628672 | Anks1a | Rat | menadione | affects expression | ISO | ANKS1A (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of ANKS1 mRNA | CTD | PMID:20044591 | Anks1a | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of ANKS1A mRNA | CTD | PMID:30047161 | Anks1a | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of ANKS1A gene | CTD | PMID:35440735 | Anks1a | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ANKS1A mRNA | CTD | PMID:25729387 | Anks1a | Rat | paracetamol | affects expression | ISO | Anks1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of ANKS1 mRNA | CTD | PMID:17562736 | Anks1a | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of ANKS1A mRNA | CTD | PMID:33387578 | Anks1a | Rat | paracetamol | increases expression | ISO | ANKS1A (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ANKS1A mRNA | CTD | PMID:22230336 | Anks1a | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Anks1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ANKS1 mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Anks1a | Rat | SB 431542 | multiple interactions | ISO | ANKS1A (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of ANKS1A more ... | CTD | PMID:37664457 | Anks1a | Rat | sodium fluoride | increases expression | ISO | Anks1 (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of ANKS1 protein | CTD | PMID:28918527 | Anks1a | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of ANKS1A mRNA | CTD | PMID:19281266 | Anks1a | Rat | temozolomide | increases expression | ISO | ANKS1A (Homo sapiens) | 6480464 | Temozolomide results in increased expression of ANKS1A mRNA | CTD | PMID:31758290 | Anks1a | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of ANKS1A mRNA | CTD | PMID:34492290 | Anks1a | Rat | titanium dioxide | affects methylation | ISO | Anks1 (Mus musculus) | 6480464 | titanium dioxide affects the methylation of ANKS1 gene | CTD | PMID:35295148 | Anks1a | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ANKS1A mRNA | CTD | PMID:25729387 | Anks1a | Rat | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of ANKS1A mRNA | CTD | PMID:25729387 | Anks1a | Rat | triphenyl phosphate | affects expression | ISO | ANKS1A (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of ANKS1A mRNA | CTD | PMID:37042841 | Anks1a | Rat | tungsten | decreases expression | ISO | Anks1 (Mus musculus) | 6480464 | Tungsten results in decreased expression of ANKS1 mRNA | CTD | PMID:30912803 | Anks1a | Rat | valproic acid | increases expression | ISO | Anks1 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of ANKS1 mRNA | CTD | PMID:20546886 | | 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