Dym (dymeclin) - Rat Genome Database

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Gene: Dym (dymeclin) Rattus norvegicus
Analyze
Symbol: Dym
Name: dymeclin
RGD ID: 1309111
Description: Predicted to enable enzyme binding activity. Predicted to be involved in Golgi organization and bone development. Predicted to be located in cytoplasm. Predicted to be active in Golgi apparatus. Human ortholog(s) of this gene implicated in Dyggve-Melchior-Clausen disease; Smith-McCort dysplasia 1; and osteochondrodysplasia. Orthologous to human DYM (dymeclin); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bis(2-chloroethyl) sulfide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC291433; RGD1309111; similar to RIKEN cDNA 4933427L07
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81870,879,835 - 71,176,006 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1870,880,255 - 71,176,004 (+)EnsemblGRCr8
mRatBN7.21868,605,131 - 68,900,905 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1868,605,185 - 68,900,903 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1870,718,041 - 71,013,638 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01871,386,410 - 71,683,811 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01869,244,060 - 69,539,675 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01870,996,074 - 71,313,033 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1870,996,044 - 71,313,084 (+)Ensemblrn6Rnor6.0
Rnor_5.01870,178,416 - 70,449,688 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41871,889,053 - 72,188,251 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1866,780,263 - 67,073,707 (+)NCBICelera
RGSC_v3.11871,962,174 - 72,261,226 (+)NCBI
Cytogenetic Map18q12.2NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO,ISS)
Golgi apparatus  (IBA,IEA,ISO,ISS)
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Mental retardation and abnormal skeletal development (Dyggve-Melchior-Clausen dysplasia) due to mutations in a novel, evolutionarily conserved gene. Cohn DH, etal., Am J Hum Genet. 2003 Feb;72(2):419-28. Epub 2002 Dec 16.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:21280149  


Genomics

Comparative Map Data
Dym
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81870,879,835 - 71,176,006 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1870,880,255 - 71,176,004 (+)EnsemblGRCr8
mRatBN7.21868,605,131 - 68,900,905 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1868,605,185 - 68,900,903 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1870,718,041 - 71,013,638 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01871,386,410 - 71,683,811 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01869,244,060 - 69,539,675 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01870,996,074 - 71,313,033 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1870,996,044 - 71,313,084 (+)Ensemblrn6Rnor6.0
Rnor_5.01870,178,416 - 70,449,688 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41871,889,053 - 72,188,251 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1866,780,263 - 67,073,707 (+)NCBICelera
RGSC_v3.11871,962,174 - 72,261,226 (+)NCBI
Cytogenetic Map18q12.2NCBI
DYM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381849,036,387 - 49,460,645 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1849,036,387 - 49,461,347 (-)Ensemblhg38GRCh38
GRCh371846,562,757 - 46,987,015 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361844,824,170 - 45,241,077 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341844,824,169 - 45,241,077NCBI
Celera1843,423,709 - 43,842,456 (-)NCBICelera
Cytogenetic Map18q21.1NCBI
HuRef1843,422,918 - 43,840,755 (-)NCBIHuRef
CHM1_11846,565,142 - 46,982,392 (-)NCBICHM1_1
T2T-CHM13v2.01849,231,816 - 49,658,383 (-)NCBIT2T-CHM13v2.0
Dym
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391875,151,772 - 75,420,037 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1875,151,852 - 75,420,035 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381875,018,699 - 75,286,966 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1875,018,781 - 75,286,964 (+)Ensemblmm10GRCm38
MGSCv371875,178,426 - 75,446,620 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361875,144,137 - 75,412,331 (+)NCBIMGSCv36mm8
Celera1876,242,337 - 76,521,558 (+)NCBICelera
Cytogenetic Map18E3NCBI
cM Map1850.97NCBI
Dym
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540234,150,783 - 34,542,507 (-)Ensembl
ChiLan1.0NW_00495540234,150,783 - 34,541,944 (-)NCBIChiLan1.0ChiLan1.0
DYM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21766,578,224 - 66,989,529 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11852,268,524 - 52,682,132 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01842,427,493 - 42,842,450 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11845,780,831 - 46,179,616 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1845,783,379 - 46,162,835 (-)EnsemblpanPan2panpan1.1
DYM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1779,286,558 - 79,629,451 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl779,286,614 - 79,629,043 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha778,691,499 - 79,034,045 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0779,353,467 - 79,696,604 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl779,353,400 - 79,697,033 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1779,068,269 - 79,410,974 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0779,098,408 - 79,441,226 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0779,383,285 - 79,726,463 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dym
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494438,237,505 - 38,575,582 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649713,476,326 - 13,818,059 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649713,476,376 - 13,816,515 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl198,638,339 - 99,024,642 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1198,642,506 - 99,024,664 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21108,216,906 - 108,352,210 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DYM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11831,513,665 - 31,902,064 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1831,513,735 - 31,901,811 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660505,734,433 - 6,137,618 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dym
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477812,541,566 - 12,977,314 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477812,541,566 - 12,977,319 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Dym
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11556,681,711 - 56,961,451 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dym
2539 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:282
Count of miRNA genes:129
Interacting mature miRNAs:137
Transcripts:ENSRNOT00000024950, ENSRNOT00000066336
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182507112683910656Rat
1331730Scl27Serum cholesterol level QTL 273.826blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)185449080186134022Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182349405785487725Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)186438376279484311Rat
631834Sach3Saccharin preference QTL 33.90.01consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)183857591983575919Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182682218671822186Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182682218671822186Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182682218671822186Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184562030686134022Rat
7794793Mcs34Mammary carcinoma susceptibility QTL 341.54mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)186563556785897775Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182682218671822186Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184891573786134022Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184891573786134022Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182682218671822186Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182682218671822186Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183199089176990891Rat
1331770Bp234Blood pressure QTL 2343.807arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184562030686134022Rat
2301969Bp324Blood pressure QTL 3244.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186198220476619168Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181206648285493247Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183161050585493247Rat
12880368Bw187Body weight QTL 1870.045body mass (VT:0001259)body weight (CMO:0000012)183337915878379158Rat
724542Kidm2Kidney mass QTL 22.6kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)186144685386134022Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)184046238385462383Rat
1359020Ppulsi2Prepulse inhibition QTL 22.71prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)185449080176272247Rat
2312600Bp341Blood pressure QTL 3410.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186160038472538878Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)183199089176990891Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181206648285493247Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228086134022Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)183337915878379158Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)183337915878379158Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)183337915878379158Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)185079521286134022Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182682218671822186Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183152278376522783Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)183337915878379158Rat
61384Bp48Blood pressure QTL 4819.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186289225779484461Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183337915878379158Rat
12904073Kidm71Kidney mass QTL 710.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)183337915878379158Rat
738008Hcar14Hepatocarcinoma resistance QTL 144.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion number (CMO:0001462)185782524385493247Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183161050577371277Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183612162681121626Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)183199089176990891Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184891573786134022Rat
631509Sald2Serum aldosterone level QTL 22.9blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)182641582171415821Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183164450879484311Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)186584644786134022Rat
1598832Glom11Glomerulus QTL 112.9kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)185326667186134022Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181955353285493247Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)183199089176990891Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)185079521286134022Rat
631675Iddm15Insulin dependent diabetes mellitus QTL 15urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)186289225779484461Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183161050572538878Rat

Markers in Region
D18Rat83  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81870,906,674 - 70,906,819 (+)Marker Load Pipeline
mRatBN7.21868,631,562 - 68,631,709 (+)MAPPERmRatBN7.2
Rnor_6.01871,028,936 - 71,029,080NCBIRnor6.0
Rnor_5.01870,165,216 - 70,165,360UniSTSRnor5.0
RGSC_v3.41871,916,282 - 71,916,427RGDRGSC3.4
RGSC_v3.41871,916,283 - 71,916,427UniSTSRGSC3.4
Celera1866,806,536 - 66,806,680UniSTS
RGSC_v3.11871,989,396 - 71,989,686RGD
SHRSP x BN Map1843.2499UniSTS
SHRSP x BN Map1843.2499RGD
Cytogenetic Map18q12.3UniSTS
RH134522  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21868,900,668 - 68,900,857 (+)MAPPERmRatBN7.2
Rnor_6.01871,312,797 - 71,312,985NCBIRnor6.0
Rnor_5.01870,449,452 - 70,449,640UniSTSRnor5.0
RGSC_v3.41872,188,015 - 72,188,203UniSTSRGSC3.4
Celera1867,073,471 - 67,073,659UniSTS
RH 3.4 Map18710.5UniSTS
Cytogenetic Map18q12.3UniSTS
RH143452  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21868,725,014 - 68,725,137 (+)MAPPERmRatBN7.2
Rnor_6.01871,137,349 - 71,137,471NCBIRnor6.0
Rnor_5.01870,273,614 - 70,273,736UniSTSRnor5.0
RGSC_v3.41872,011,886 - 72,012,008UniSTSRGSC3.4
Celera1866,897,029 - 66,897,151UniSTS
RH 3.4 Map18710.4UniSTS
Cytogenetic Map18q12.3UniSTS
G47243  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21868,817,139 - 68,817,391 (+)MAPPERmRatBN7.2
Rnor_6.01871,229,437 - 71,229,686NCBIRnor6.0
Rnor_5.01870,365,890 - 70,366,139UniSTSRnor5.0
RGSC_v3.41872,104,065 - 72,104,314UniSTSRGSC3.4
Celera1866,989,187 - 66,989,436UniSTS
Cytogenetic Map18q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC098944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC168151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB712341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO558582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV722630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EV765460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000024950   ⟹   ENSRNOP00000024950
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1870,880,255 - 71,176,004 (+)Ensembl
mRatBN7.2 Ensembl1868,605,226 - 68,900,898 (+)Ensembl
Rnor_6.0 Ensembl1870,996,044 - 71,313,084 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000066336   ⟹   ENSRNOP00000060744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1870,880,332 - 71,176,004 (+)Ensembl
mRatBN7.2 Ensembl1868,605,202 - 68,900,903 (+)Ensembl
Rnor_6.0 Ensembl1870,996,140 - 71,313,031 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110740   ⟹   ENSRNOP00000081467
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1870,880,292 - 71,176,004 (+)Ensembl
mRatBN7.2 Ensembl1868,605,185 - 68,900,863 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000152426   ⟹   ENSRNOP00000111989
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1870,880,517 - 71,176,004 (+)Ensembl
RefSeq Acc Id: NM_001106133   ⟹   NP_001099603
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,880,332 - 71,176,006 (+)NCBI
mRatBN7.21868,605,202 - 68,900,905 (+)NCBI
Rnor_6.01870,996,140 - 71,313,033 (+)NCBI
Rnor_5.01870,178,416 - 70,449,688 (+)NCBI
RGSC_v3.41871,889,053 - 72,188,251 (+)RGD
Celera1866,780,263 - 67,073,707 (+)RGD
Sequence:
RefSeq Acc Id: XM_008772103   ⟹   XP_008770325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
mRatBN7.21868,605,138 - 68,900,905 (+)NCBI
Rnor_6.01870,996,076 - 71,313,033 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600877   ⟹   XP_017456366
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
mRatBN7.21868,605,134 - 68,900,905 (+)NCBI
Rnor_6.01870,996,074 - 71,313,033 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600878   ⟹   XP_017456367
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,880,624 - 71,176,006 (+)NCBI
mRatBN7.21868,605,481 - 68,900,905 (+)NCBI
Rnor_6.01870,996,382 - 71,313,033 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600879   ⟹   XP_017456368
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
mRatBN7.21868,605,135 - 68,900,905 (+)NCBI
Rnor_6.01870,996,075 - 71,313,033 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600880   ⟹   XP_017456369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
mRatBN7.21868,605,136 - 68,900,905 (+)NCBI
Rnor_6.01870,996,075 - 71,313,033 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039096637   ⟹   XP_038952565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
mRatBN7.21868,605,131 - 68,900,905 (+)NCBI
RefSeq Acc Id: XM_039096638   ⟹   XP_038952566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
mRatBN7.21868,605,135 - 68,900,905 (+)NCBI
RefSeq Acc Id: XM_063277161   ⟹   XP_063133231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
RefSeq Acc Id: XM_063277162   ⟹   XP_063133232
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
RefSeq Acc Id: XM_063277164   ⟹   XP_063133234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
RefSeq Acc Id: XM_063277165   ⟹   XP_063133235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
RefSeq Acc Id: XM_063277166   ⟹   XP_063133236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,879,835 - 71,176,006 (+)NCBI
RefSeq Acc Id: NP_001099603   ⟸   NM_001106133
- UniProtKB: D3ZP27 (UniProtKB/TrEMBL),   A6KRI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770325   ⟸   XM_008772103
- Peptide Label: isoform X5
- UniProtKB: A0A0H2UHP8 (UniProtKB/TrEMBL),   A6KRI0 (UniProtKB/TrEMBL),   A6KRI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456366   ⟸   XM_017600877
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017456369   ⟸   XM_017600880
- Peptide Label: isoform X3
- UniProtKB: B4F766 (UniProtKB/Swiss-Prot),   A6KRI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456368   ⟸   XM_017600879
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017456367   ⟸   XM_017600878
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000060744   ⟸   ENSRNOT00000066336
Ensembl Acc Id: ENSRNOP00000024950   ⟸   ENSRNOT00000024950
RefSeq Acc Id: XP_038952565   ⟸   XM_039096637
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038952566   ⟸   XM_039096638
- Peptide Label: isoform X7
- UniProtKB: A0A8I6G5Z6 (UniProtKB/TrEMBL),   A6KRI1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000081467   ⟸   ENSRNOT00000110740
RefSeq Acc Id: XP_063133231   ⟸   XM_063277161
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063133235   ⟸   XM_063277165
- Peptide Label: isoform X5
- UniProtKB: A0A0H2UHP8 (UniProtKB/TrEMBL),   A6KRI0 (UniProtKB/TrEMBL),   A6KRI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133232   ⟸   XM_063277162
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063133234   ⟸   XM_063277164
- Peptide Label: isoform X5
- UniProtKB: A0A0H2UHP8 (UniProtKB/TrEMBL),   A6KRI0 (UniProtKB/TrEMBL),   A6KRI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133236   ⟸   XM_063277166
- Peptide Label: isoform X6
- UniProtKB: A6KRI1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000111989   ⟸   ENSRNOT00000152426

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B4F766-F1-model_v2 AlphaFold B4F766 1-674 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700871
Promoter ID:EPDNEW_R11393
Type:initiation region
Name:Dym_1
Description:dymeclin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01870,996,132 - 70,996,192EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309111 AgrOrtholog
BioCyc Gene G2FUF-6987 BioCyc
Ensembl Genes ENSRNOG00000018425 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024950 ENTREZGENE
  ENSRNOT00000024950.8 UniProtKB/Swiss-Prot
  ENSRNOT00000066336 ENTREZGENE
  ENSRNOT00000110740 ENTREZGENE
  ENSRNOT00000152426 ENTREZGENE
InterPro Dymeclin UniProtKB/Swiss-Prot
NCBI Gene 291433 ENTREZGENE
PANTHER DYMECLIN UniProtKB/Swiss-Prot
  PTHR12895 UniProtKB/Swiss-Prot
Pfam Dymeclin UniProtKB/Swiss-Prot
PhenoGen Dym PhenoGen
RatGTEx ENSRNOG00000018425 RatGTEx
UniProt A0A0H2UHP8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G5Z6 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LZN0_RAT UniProtKB/TrEMBL
  A6KRI0 ENTREZGENE, UniProtKB/TrEMBL
  A6KRI1 ENTREZGENE, UniProtKB/TrEMBL
  B4F766 ENTREZGENE
  D3ZP27 ENTREZGENE, UniProtKB/TrEMBL
  DYM_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Dym  dymeclin   Dym_predicted  dymeclin (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Dym_predicted  dymeclin (predicted)  RGD1309111_predicted  similar to RIKEN cDNA 4933427L07 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1309111_predicted  similar to RIKEN cDNA 4933427L07 (predicted)  LOC291433_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC291433_predicted  similar to RIKEN cDNA 4933427L07 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL