Cntln (centlein) - Rat Genome Database

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Pathways
Gene: Cntln (centlein) Rattus norvegicus
Analyze
Symbol: Cntln
Name: centlein
RGD ID: 1308101
Description: Predicted to enable protein domain specific binding activity; protein kinase binding activity; and protein-macromolecule adaptor activity. Predicted to be involved in centriole-centriole cohesion. Predicted to act upstream of or within several processes, including regulation of protein localization; single fertilization; and spermatogenesis. Predicted to be located in centriole and cytoplasm. Predicted to be active in sperm head-tail coupling apparatus. Orthologous to human CNTLN (centlein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: centlein, centrosomal protein; centrosomal protein; FLJ20276; LOC313331; LOC679640; RGD1308101; RGD1308101_predicted; similar to CLIP-190 CG5020-PA, isoform A; similar to hypothetical protein FLJ20276; similar to hypothetical protein FLJ20276 (predicted)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85104,340,801 - 104,622,491 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5104,342,173 - 104,630,976 (+)EnsemblGRCr8
mRatBN7.2599,295,865 - 99,576,402 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl599,296,000 - 99,576,396 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5101,848,671 - 101,959,009 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05103,636,983 - 103,747,285 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05103,659,530 - 103,769,855 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05103,251,986 - 103,367,088 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5103,251,986 - 103,366,264 (+)Ensemblrn6Rnor6.0
Rnor_5.05107,173,114 - 107,366,594 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45103,942,784 - 104,049,783 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera597,985,522 - 98,089,303 (+)NCBICelera
RGSC_v3.15103,747,276 - 104,091,234 (+)NCBI
Cytogenetic Map5q31NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
amenorrhea  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centriole  (IEA,ISO)
centrosome  (IEA,ISO)
cytoplasm  (IEA,ISO)
sperm head-tail coupling apparatus  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:15057822   PMID:18086554   PMID:19056867   PMID:24554434  


Genomics

Comparative Map Data
Cntln
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85104,340,801 - 104,622,491 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5104,342,173 - 104,630,976 (+)EnsemblGRCr8
mRatBN7.2599,295,865 - 99,576,402 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl599,296,000 - 99,576,396 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5101,848,671 - 101,959,009 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05103,636,983 - 103,747,285 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05103,659,530 - 103,769,855 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05103,251,986 - 103,367,088 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5103,251,986 - 103,366,264 (+)Ensemblrn6Rnor6.0
Rnor_5.05107,173,114 - 107,366,594 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45103,942,784 - 104,049,783 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera597,985,522 - 98,089,303 (+)NCBICelera
RGSC_v3.15103,747,276 - 104,091,234 (+)NCBI
Cytogenetic Map5q31NCBI
CNTLN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38917,135,040 - 17,528,634 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl917,134,982 - 17,503,923 (+)Ensemblhg38GRCh38
GRCh37917,135,038 - 17,503,921 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36917,125,038 - 17,493,917 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34917,226,567 - 17,493,920NCBI
Celera917,063,810 - 17,432,405 (+)NCBICelera
Cytogenetic Map9p22.2NCBI
HuRef917,098,828 - 17,466,175 (+)NCBIHuRef
CHM1_1917,134,947 - 17,503,979 (+)NCBICHM1_1
T2T-CHM13v2.0917,147,678 - 17,548,946 (+)NCBIT2T-CHM13v2.0
Cntln
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39484,800,024 - 85,050,160 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl484,802,546 - 85,050,158 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38484,881,787 - 85,131,923 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl484,884,309 - 85,131,921 (+)Ensemblmm10GRCm38
MGSCv37484,530,231 - 84,777,822 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36484,355,558 - 84,603,149 (+)NCBIMGSCv36mm8
Celera483,393,175 - 83,645,222 (+)NCBICelera
Cytogenetic Map4C4NCBI
cM Map440.2NCBI
Cntln
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543419,811,100 - 20,118,185 (+)NCBIChiLan1.0ChiLan1.0
CNTLN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211107,056,308 - 107,408,801 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19107,059,237 - 107,414,633 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0916,958,911 - 17,317,044 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1917,455,498 - 17,804,123 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl917,455,576 - 17,804,123 (+)EnsemblpanPan2panpan1.1
CNTLN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11137,182,288 - 37,492,121 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1137,061,451 - 37,492,049 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1135,834,165 - 36,143,007 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01138,095,981 - 38,405,183 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1138,096,079 - 38,405,875 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11136,788,102 - 37,108,588 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01136,584,883 - 36,902,010 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01137,237,866 - 37,546,424 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cntln
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947151,916,641 - 152,229,602 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493677191,750 - 405,501 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493677191,834 - 405,436 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNTLN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1205,370,499 - 205,697,786 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11205,371,716 - 205,697,831 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21229,089,937 - 229,435,748 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CNTLN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11262,157,153 - 62,511,938 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1262,156,609 - 62,511,412 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603850,305,998 - 50,670,724 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cntln
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473621,163,845 - 21,499,031 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473621,163,787 - 21,500,649 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cntln
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1168,788,052 - 69,041,193 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cntln
1878 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:523
Count of miRNA genes:250
Interacting mature miRNAs:307
Transcripts:ENSRNOT00000008757
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)573779642118779642Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
2303586Gluco52Glucose level QTL 522blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)5100826632145826632Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)584630798129630798Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)584630798129630798Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)5104018576124314782Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)592583776137583776Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)598972960143972960Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
2303618Vencon1Ventilatory control QTL 13.8respiration trait (VT:0001943)oxygen consumption (CMO:0002169)5100826632145826632Rat
7394708Emca11Estrogen-induced mammary cancer QTL 11mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)573176602118176602Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584630798129630798Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)594034903139034903Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)569474415114474415Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)595062526133270832Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)564589016109589016Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
1600362Mcs19Mammary carcinoma susceptibility QTL 192.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)582032155127032155Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)589369373134369373Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)569835120114835120Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)597492524133270832Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)573779642118779642Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)592881678137881678Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)595062526133270832Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat

Markers in Region
D5Rat196  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85104,532,087 - 104,532,223 (+)Marker Load Pipeline
mRatBN7.2599,485,997 - 99,486,133 (+)MAPPERmRatBN7.2
Rnor_6.05103,265,614 - 103,265,749NCBIRnor6.0
Rnor_5.05107,265,415 - 107,265,550UniSTSRnor5.0
RGSC_v3.45103,956,412 - 103,956,547UniSTSRGSC3.4
RGSC_v3.45103,956,411 - 103,956,547RGDRGSC3.4
Celera597,999,166 - 97,999,301UniSTS
RGSC_v3.15103,961,587 - 103,961,975RGD
SHRSP x BN Map558.1599UniSTS
SHRSP x BN Map558.1599RGD
Cytogenetic Map5q31UniSTS
BF401796  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2599,335,709 - 99,335,901 (+)MAPPERmRatBN7.2
Rnor_6.05103,063,259 - 103,063,450NCBIRnor6.0
Rnor_5.05107,067,573 - 107,067,764UniSTSRnor5.0
RGSC_v3.45103,798,712 - 103,798,903UniSTSRGSC3.4
Celera597,864,802 - 97,864,993UniSTS
RH 3.4 Map5741.1UniSTS
Cytogenetic Map5q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 67 163 91 90 59 80 59 6 343 179 11 142 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001114402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001438394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001438395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039110763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB369315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF394214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU759324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB699924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000008757   ⟹   ENSRNOP00000008757
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5104,342,173 - 104,622,485 (+)Ensembl
mRatBN7.2 Ensembl599,296,414 - 99,576,396 (+)Ensembl
Rnor_6.0 Ensembl5103,251,986 - 103,366,264 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098986   ⟹   ENSRNOP00000097246
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5104,342,173 - 104,622,485 (+)Ensembl
mRatBN7.2 Ensembl599,296,000 - 99,576,396 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112551   ⟹   ENSRNOP00000080911
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5104,342,173 - 104,622,485 (+)Ensembl
mRatBN7.2 Ensembl599,296,000 - 99,576,396 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114509   ⟹   ENSRNOP00000097573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5104,342,210 - 104,622,485 (+)Ensembl
mRatBN7.2 Ensembl599,296,000 - 99,576,396 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000127933   ⟹   ENSRNOP00000105526
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5104,342,173 - 104,593,992 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000173143   ⟹   ENSRNOP00000106717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5104,457,710 - 104,630,976 (+)Ensembl
RefSeq Acc Id: NM_001114402   ⟹   NP_001107874
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,518,466 - 104,622,488 (+)NCBI
mRatBN7.2599,472,376 - 99,576,399 (+)NCBI
Rnor_6.05103,251,986 - 103,367,088 (+)NCBI
Rnor_5.05107,173,114 - 107,366,594 (+)NCBI
RGSC_v3.45103,942,784 - 104,049,783 (+)RGD
Celera597,985,522 - 98,089,303 (+)RGD
Sequence:
RefSeq Acc Id: XM_039110761   ⟹   XP_038966689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,463,960 - 104,622,491 (+)NCBI
mRatBN7.2599,417,874 - 99,576,402 (+)NCBI
RefSeq Acc Id: XM_039110763   ⟹   XP_038966691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,498,389 - 104,622,491 (+)NCBI
mRatBN7.2599,454,428 - 99,576,402 (+)NCBI
RefSeq Acc Id: XM_063288373   ⟹   XP_063144443
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,622,491 (+)NCBI
RefSeq Acc Id: XM_063288374   ⟹   XP_063144444
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,622,491 (+)NCBI
RefSeq Acc Id: XM_063288375   ⟹   XP_063144445
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,622,491 (+)NCBI
RefSeq Acc Id: XM_063288376   ⟹   XP_063144446
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,622,491 (+)NCBI
RefSeq Acc Id: XM_063288377   ⟹   XP_063144447
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,622,491 (+)NCBI
RefSeq Acc Id: XM_063288378   ⟹   XP_063144448
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,622,491 (+)NCBI
RefSeq Acc Id: XM_063288379   ⟹   XP_063144449
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,622,491 (+)NCBI
RefSeq Acc Id: XM_063288380   ⟹   XP_063144450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,622,491 (+)NCBI
RefSeq Acc Id: XM_063288381   ⟹   XP_063144451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,622,491 (+)NCBI
RefSeq Acc Id: XM_063288382   ⟹   XP_063144452
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,622,491 (+)NCBI
RefSeq Acc Id: XM_063288383   ⟹   XP_063144453
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,622,491 (+)NCBI
RefSeq Acc Id: XM_063288384   ⟹   XP_063144454
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,601,985 (+)NCBI
RefSeq Acc Id: XM_063288385   ⟹   XP_063144455
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,588,899 (+)NCBI
RefSeq Acc Id: XM_063288387   ⟹   XP_063144457
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,601,985 (+)NCBI
RefSeq Acc Id: XM_063288388   ⟹   XP_063144458
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,588,434 (+)NCBI
RefSeq Acc Id: XM_063288389   ⟹   XP_063144459
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,552,367 (+)NCBI
RefSeq Acc Id: XM_063288390   ⟹   XP_063144460
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,552,319 (+)NCBI
RefSeq Acc Id: XM_063288391   ⟹   XP_063144461
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85104,340,801 - 104,533,440 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001107874 (Get FASTA)   NCBI Sequence Viewer  
  NP_001425323 (Get FASTA)   NCBI Sequence Viewer  
  NP_001425324 (Get FASTA)   NCBI Sequence Viewer  
  XP_038966689 (Get FASTA)   NCBI Sequence Viewer  
  XP_038966691 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144443 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144444 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144445 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144446 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144447 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144448 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144449 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144450 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144451 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144452 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144453 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144454 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144455 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144457 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144458 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144459 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144460 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144461 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A9ZSY0 (Get FASTA)   NCBI Sequence Viewer  
  BAF98578 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000008757
  ENSRNOP00000080911
  ENSRNOP00000097246
  ENSRNOP00000097573
  ENSRNOP00000105526
  ENSRNOP00000106717
RefSeq Acc Id: NP_001107874   ⟸   NM_001114402
- Sequence:
Ensembl Acc Id: ENSRNOP00000008757   ⟸   ENSRNOT00000008757
RefSeq Acc Id: XP_038966689   ⟸   XM_039110761
- Peptide Label: isoform X19
- UniProtKB: A0A8I6ASB3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038966691   ⟸   XM_039110763
- Peptide Label: isoform X20
- UniProtKB: A0A8I6ASB3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000080911   ⟸   ENSRNOT00000112551
Ensembl Acc Id: ENSRNOP00000097246   ⟸   ENSRNOT00000098986
Ensembl Acc Id: ENSRNOP00000097573   ⟸   ENSRNOT00000114509
RefSeq Acc Id: XP_063144443   ⟸   XM_063288373
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZRW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144450   ⟸   XM_063288380
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZRW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144445   ⟸   XM_063288375
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZRW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144444   ⟸   XM_063288374
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZRW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144446   ⟸   XM_063288376
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZRW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144447   ⟸   XM_063288377
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZRW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144448   ⟸   XM_063288378
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZRW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144449   ⟸   XM_063288379
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZRW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144451   ⟸   XM_063288381
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZRW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144452   ⟸   XM_063288382
- Peptide Label: isoform X10
- UniProtKB: A0A8I6ASX4 (UniProtKB/TrEMBL),   A0A8I5ZRW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144453   ⟸   XM_063288383
- Peptide Label: isoform X11
- UniProtKB: A0A8I5ZRW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144454   ⟸   XM_063288384
- Peptide Label: isoform X12
- UniProtKB: A0A8I5ZRW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144457   ⟸   XM_063288387
- Peptide Label: isoform X14
- UniProtKB: A0A8I5ZRW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144455   ⟸   XM_063288385
- Peptide Label: isoform X13
- UniProtKB: A0A8I5ZRW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144458   ⟸   XM_063288388
- Peptide Label: isoform X15
RefSeq Acc Id: XP_063144459   ⟸   XM_063288389
- Peptide Label: isoform X16
RefSeq Acc Id: XP_063144460   ⟸   XM_063288390
- Peptide Label: isoform X17
RefSeq Acc Id: XP_063144461   ⟸   XM_063288391
- Peptide Label: isoform X18
Ensembl Acc Id: ENSRNOP00000105526   ⟸   ENSRNOT00000127933
Ensembl Acc Id: ENSRNOP00000106717   ⟸   ENSRNOT00000173143

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A9ZSY0-F1-model_v2 AlphaFold A9ZSY0 1-721 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308101 AgrOrtholog
BioCyc Gene G2FUF-40856 BioCyc
Ensembl Genes ENSRNOG00000043151 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000008757 ENTREZGENE
  ENSRNOT00000098986 ENTREZGENE
  ENSRNOT00000112551 ENTREZGENE
  ENSRNOT00000114509 ENTREZGENE
  ENSRNOT00000127933 ENTREZGENE
  ENSRNOT00000173143 ENTREZGENE
InterPro CNTLN UniProtKB/Swiss-Prot
KEGG Report rno:679640 UniProtKB/Swiss-Prot
NCBI Gene Cntln ENTREZGENE
PANTHER CENTLEIN UniProtKB/Swiss-Prot
  PTHR18957 UniProtKB/Swiss-Prot
PhenoGen Cntln PhenoGen
RatGTEx ENSRNOG00000043151 RatGTEx
UniProt A0A8I5ZRW7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ASB3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ASX4 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LLX9_RAT UniProtKB/TrEMBL
  A0ABK0LXD8_RAT UniProtKB/TrEMBL
  A9ZSY0 ENTREZGENE, UniProtKB/Swiss-Prot
  F1LMT2_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Cntln  centlein  Cntln  centlein, centrosomal protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-12-09 Cntln  centlein, centrosomal protein  RGD1308101  similar to hypothetical protein FLJ20276  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-28 RGD1308101  similar to hypothetical protein FLJ20276   RGD1308101  similar to hypothetical protein FLJ20276 (predicted)  'predicted' is removed from gene name 2292626 APPROVED
2008-02-11 RGD1308101    RGD1308101_predicted  similar to hypothetical protein FLJ20276 (predicted)  Symbol updated 1299863 APPROVED
2008-02-11 RGD1308101_predicted  similar to hypothetical protein FLJ20276 (predicted)  LOC679640  similar to CLIP-190 CG5020-PA, isoform A  Data merged from RGD:1585949 737654 APPROVED
2006-11-19 LOC679640  similar to CLIP-190 CG5020-PA, isoform A      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 RGD1308101_predicted  similar to hypothetical protein FLJ20276 (predicted)  LOC313331_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC313331_predicted  similar to hypothetical protein FLJ20276 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL