Gene: Cntln (centlein) Rattus norvegicus
Analyze
Symbol:
Cntln
Name:
centlein
RGD ID:
1308101
Description:
Predicted to enable protein domain specific binding activity; protein kinase binding activity; and protein-macromolecule adaptor activity. Predicted to be involved in centriole-centriole cohesion. Predicted to act upstream of or within several processes, including regulation of protein localization; single fertilization; and spermatogenesis. Predicted to be located in centriole and cytoplasm. Predicted to be active in sperm head-tail coupling apparatus. Orthologous to human CNTLN (centlein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; atrazine.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
centlein, centrosomal protein; centrosomal protein; FLJ20276; LOC313331; LOC679640; RGD1308101; RGD1308101_predicted; similar to CLIP-190 CG5020-PA, isoform A; similar to hypothetical protein FLJ20276; similar to hypothetical protein FLJ20276 (predicted)
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
CNTLN (centlein)
HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Cntln (centlein, centrosomal protein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Cntln (centlein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
CNTLN (centlein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
CNTLN (centlein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Cntln (centlein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
CNTLN (centlein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
CNTLN (centlein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Cntln (centlein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Cntln (centlein)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
RBBP6 (RB binding protein 6, ubiquitin ligase)
HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
CNTLN (centlein)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Cntln (centlein, centrosomal protein)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Cntln (centlein, centrosomal protein)
Alliance
DIOPT (Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
cntln (centlein, centrosomal protein)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
cntln (centlein, centrosomal protein)
Alliance
DIOPT (Ensembl Compara|Hieranoid|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
cntln
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
cntln
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PhylomeDB)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 5 104,340,801 - 104,622,491 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 5 104,342,173 - 104,630,976 (+) Ensembl GRCr8 mRatBN7.2 5 99,295,865 - 99,576,402 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 5 99,296,000 - 99,576,396 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 5 101,848,671 - 101,959,009 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 5 103,636,983 - 103,747,285 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 5 103,659,530 - 103,769,855 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 5 103,251,986 - 103,367,088 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 5 103,251,986 - 103,366,264 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 5 107,173,114 - 107,366,594 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 5 103,942,784 - 104,049,783 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 5 97,985,522 - 98,089,303 (+) NCBI Celera RGSC_v3.1 5 103,747,276 - 104,091,234 (+) NCBI Cytogenetic Map 5 q31 NCBI
JBrowse:
Imported Disease Annotations - ClinVar
Only show annotations with direct experimental evidence (0 objects hidden)
Cntln Rat (-)-demecolcine decreases expression ISO CNTLN (Homo sapiens) 6480464 Demecolcine results in decreased expression of CNTLN mRNA CTD PMID:23649840 Cntln Rat (-)-epigallocatechin 3-gallate multiple interactions ISO CNTLN (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CNTLN mRNA CTD PMID:22079256 Cntln Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Cntln (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Cntln Rat 1,2-dimethylhydrazine decreases expression ISO Cntln (Mus musculus) 6480464 1,2-Dimethylhydrazine results in decreased expression of CNTLN mRNA CTD PMID:22206623 Cntln Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Cntln (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Cntln Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Cntln (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Cntln Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO CNTLN (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of CNTLN mRNA CTD PMID:22574217 Cntln Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CNTLN mRNA CTD PMID:32109520 Cntln Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Cntln (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Cntln Rat 4,4'-sulfonyldiphenol increases methylation ISO CNTLN (Homo sapiens) 6480464 bisphenol S results in increased methylation of CNTLN gene CTD PMID:31601247 Cntln Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of CNTLN mRNA CTD PMID:31881176 Cntln Rat aflatoxin M1 decreases expression ISO CNTLN (Homo sapiens) 6480464 Aflatoxin M1 results in decreased expression of CNTLN mRNA CTD PMID:30928695 Cntln Rat aristolochic acid A decreases expression ISO CNTLN (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of CNTLN mRNA CTD PMID:33212167 Cntln Rat arsane multiple interactions ISO CNTLN (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Cntln Rat arsenic atom multiple interactions ISO CNTLN (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Cntln Rat atrazine affects methylation EXP 6480464 Atrazine affects the methylation of CNTLN gene CTD PMID:35440735 Cntln Rat benzo[a]pyrene increases expression ISO CNTLN (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of CNTLN mRNA CTD PMID:22316170 Cntln Rat benzo[a]pyrene increases methylation ISO CNTLN (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of CNTLN promoter CTD PMID:27901495 Cntln Rat benzo[a]pyrene increases methylation ISO Cntln (Mus musculus) 6480464 Benzo(a)pyrene results in increased methylation of CNTLN 3' UTR; Benzo(a)pyrene results in increased methylation of more ... CTD PMID:27901495 Cntln Rat benzo[e]pyrene decreases methylation ISO CNTLN (Homo sapiens) 6480464 benzo(e)pyrene results in decreased methylation of CNTLN intron CTD PMID:30157460 Cntln Rat bis(2-ethylhexyl) phthalate decreases expression ISO Cntln (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of CNTLN mRNA CTD PMID:33754040 Cntln Rat bisphenol A affects expression ISO CNTLN (Homo sapiens) 6480464 bisphenol A affects the expression of CNTLN mRNA CTD PMID:22574217 Cntln Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CNTLN mRNA CTD PMID:34947998 Cntln Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of CNTLN mRNA CTD PMID:25181051 Cntln Rat butanal decreases expression ISO CNTLN (Homo sapiens) 6480464 butyraldehyde results in decreased expression of CNTLN mRNA CTD PMID:26079696 Cntln Rat cadmium dichloride decreases expression ISO Cntln (Mus musculus) 6480464 Cadmium Chloride results in decreased expression of CNTLN mRNA CTD PMID:24982889 Cntln Rat carbon nanotube decreases expression ISO Cntln (Mus musculus) 6480464 Nanotubes, Carbon analog results in decreased expression of CNTLN mRNA; Nanotubes, Carbon results in decreased more ... CTD PMID:25554681 Cntln Rat choline multiple interactions ISO Cntln (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... CTD PMID:20938992 Cntln Rat cisplatin decreases expression ISO CNTLN (Homo sapiens) 6480464 Cisplatin results in decreased expression of CNTLN mRNA CTD PMID:27392435 Cntln Rat cisplatin multiple interactions ISO CNTLN (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of CNTLN mRNA CTD PMID:27392435 Cntln Rat DDE increases expression ISO CNTLN (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of CNTLN mRNA CTD PMID:38568856 Cntln Rat Dibutyl phosphate affects expression ISO CNTLN (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of CNTLN mRNA CTD PMID:37042841 Cntln Rat dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of CNTLN mRNA CTD PMID:21266533 Cntln Rat dimethyl sulfoxide increases expression ISO CNTLN (Homo sapiens) 6480464 Dimethyl Sulfoxide results in increased expression of CNTLN mRNA CTD PMID:39709020 Cntln Rat dorsomorphin multiple interactions ISO CNTLN (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Cntln Rat doxorubicin decreases expression ISO CNTLN (Homo sapiens) 6480464 Doxorubicin results in decreased expression of CNTLN mRNA CTD PMID:29803840 Cntln Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of CNTLN mRNA CTD PMID:29391264 Cntln Rat epoxiconazole decreases expression ISO Cntln (Mus musculus) 6480464 epoxiconazole results in decreased expression of CNTLN mRNA CTD PMID:35436446 Cntln Rat folic acid multiple interactions ISO Cntln (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... CTD PMID:20938992 Cntln Rat folic acid decreases expression ISO Cntln (Mus musculus) 6480464 Folic Acid results in decreased expression of CNTLN mRNA CTD PMID:25629700 Cntln Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of CNTLN mRNA CTD PMID:33387578 Cntln Rat inulin multiple interactions ISO Cntln (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of CNTLN mRNA CTD PMID:36331819 Cntln Rat L-methionine multiple interactions ISO Cntln (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... CTD PMID:20938992 Cntln Rat leflunomide increases expression ISO CNTLN (Homo sapiens) 6480464 leflunomide results in increased expression of CNTLN mRNA CTD PMID:28988120 Cntln Rat manganese atom multiple interactions ISO CNTLN (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Cntln Rat manganese(0) multiple interactions ISO CNTLN (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Cntln Rat manganese(II) chloride multiple interactions ISO CNTLN (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Cntln Rat methapyrilene decreases methylation ISO CNTLN (Homo sapiens) 6480464 Methapyrilene results in decreased methylation of CNTLN intron CTD PMID:30157460 Cntln Rat methylmercury chloride decreases expression ISO CNTLN (Homo sapiens) 6480464 methylmercuric chloride results in decreased expression of CNTLN mRNA CTD PMID:28001369 Cntln Rat paracetamol affects expression ISO Cntln (Mus musculus) 6480464 Acetaminophen affects the expression of CNTLN mRNA CTD PMID:17562736 Cntln Rat paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of CNTLN mRNA CTD PMID:33387578 Cntln Rat paracetamol decreases expression ISO CNTLN (Homo sapiens) 6480464 Acetaminophen results in decreased expression of CNTLN mRNA CTD PMID:29067470 Cntln Rat PCB138 multiple interactions ISO Cntln (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Cntln Rat pentanal decreases expression ISO CNTLN (Homo sapiens) 6480464 pentanal results in decreased expression of CNTLN mRNA CTD PMID:26079696 Cntln Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Cntln (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of CNTLN mRNA CTD PMID:36331819 Cntln Rat perfluorooctanoic acid increases expression ISO CNTLN (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of CNTLN mRNA CTD PMID:36326898 Cntln Rat phenylmercury acetate decreases expression ISO CNTLN (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of CNTLN mRNA CTD PMID:26272509 Cntln Rat phenylmercury acetate multiple interactions ISO CNTLN (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Cntln Rat potassium chromate multiple interactions ISO CNTLN (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CNTLN mRNA CTD PMID:22079256 Cntln Rat potassium chromate decreases expression ISO CNTLN (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of CNTLN mRNA CTD PMID:22079256 Cntln Rat resveratrol multiple interactions ISO CNTLN (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of CNTLN mRNA CTD PMID:23557933 Cntln Rat rifampicin increases expression ISO CNTLN (Homo sapiens) 6480464 Rifampin results in increased expression of CNTLN mRNA CTD PMID:24552687 Cntln Rat SB 431542 multiple interactions ISO CNTLN (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Cntln Rat silicon dioxide increases methylation ISO CNTLN (Homo sapiens) 6480464 Silicon Dioxide results in increased methylation of CNTLN gene; Silicon Dioxide results in increased methylation more ... CTD PMID:34973136 Cntln Rat sodium arsenate affects expression ISO Cntln (Mus musculus) 6480464 sodium arsenate affects the expression of CNTLN mRNA CTD PMID:39847705 Cntln Rat sodium arsenite decreases expression ISO CNTLN (Homo sapiens) 6480464 sodium arsenite results in decreased expression of CNTLN mRNA CTD PMID:38568856 Cntln Rat sodium arsenite multiple interactions ISO CNTLN (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... CTD PMID:39836092 Cntln Rat sunitinib increases expression ISO CNTLN (Homo sapiens) 6480464 Sunitinib results in increased expression of CNTLN mRNA CTD PMID:31533062 Cntln Rat titanium dioxide increases methylation ISO CNTLN (Homo sapiens) 6480464 titanium dioxide results in increased methylation of CNTLN gene; titanium dioxide results in increased methylation more ... CTD PMID:34973136 Cntln Rat trichostatin A increases expression ISO CNTLN (Homo sapiens) 6480464 trichostatin A results in increased expression of CNTLN mRNA CTD PMID:24935251|PMID:26272509 Cntln Rat trichostatin A multiple interactions ISO CNTLN (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Cntln Rat trovafloxacin decreases expression ISO Cntln (Mus musculus) 6480464 trovafloxacin results in decreased expression of CNTLN mRNA CTD PMID:35537566 Cntln Rat valproic acid affects expression ISO CNTLN (Homo sapiens) 6480464 Valproic Acid affects the expression of CNTLN mRNA CTD PMID:25979313 Cntln Rat valproic acid multiple interactions ISO CNTLN (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Cntln Rat valproic acid decreases expression ISO CNTLN (Homo sapiens) 6480464 Valproic Acid results in decreased expression of CNTLN mRNA CTD PMID:27188386|PMID:28001369 Cntln Rat valproic acid increases expression ISO CNTLN (Homo sapiens) 6480464 Valproic Acid results in increased expression of CNTLN mRNA CTD PMID:26272509 Cntln Rat vincristine decreases expression ISO CNTLN (Homo sapiens) 6480464 Vincristine results in decreased expression of CNTLN mRNA CTD PMID:23649840