Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | U2surp | Rat | (-)-demecolcine | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Demecolcine results in decreased expression of U2SURP mRNA | CTD | PMID:23649840 | U2surp | Rat | (-)-demecolcine | increases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Demecolcine results in increased expression of U2SURP mRNA | CTD | PMID:23649840 | U2surp | Rat | (S)-nicotine | increases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Nicotine results in increased expression of U2SURP mRNA | CTD | PMID:16949557 | U2surp | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SR140 mRNA; Tetrachlorodibenzodioxin results in decreased expression of U2SURP more ... | CTD | PMID:20106945|PMID:21632981 | U2surp | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of U2SURP mRNA | CTD | PMID:34747641 | U2surp | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | U2surp (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of U2SURP mRNA | CTD | PMID:24680724 | U2surp | Rat | 2-methylcholine | affects expression | ISO | U2SURP (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of SR140 mRNA | CTD | PMID:21179406 | U2surp | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of U2SURP protein | CTD | PMID:34915118 | U2surp | Rat | 5-fluorouracil | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Fluorouracil results in decreased expression of U2SURP mRNA | CTD | PMID:16510598 | U2surp | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of U2SURP mRNA | CTD | PMID:30047161 | U2surp | Rat | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of U2SURP mRNA | CTD | PMID:28959563 | U2surp | Rat | aflatoxin B1 | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of U2SURP mRNA | CTD | PMID:21641981 | U2surp | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of U2SURP mRNA | CTD | PMID:30047161 | U2surp | Rat | antirheumatic drug | increases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of SR140 mRNA | CTD | PMID:24449571 | U2surp | Rat | aristolochic acid A | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of U2SURP mRNA | CTD | PMID:33212167 | U2surp | Rat | benzo[a]pyrene | increases methylation | ISO | U2SURP (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SR140 3' UTR | CTD | PMID:27901495 | U2surp | Rat | benzo[a]pyrene | decreases methylation | ISO | U2surp (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of U2SURP intron | CTD | PMID:27901495 | U2surp | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of U2SURP mRNA | CTD | PMID:19150397|PMID:26238291 | U2surp | Rat | beta-lapachone | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of U2SURP mRNA | CTD | PMID:38218311 | U2surp | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | U2surp (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of U2SURP mRNA | CTD | PMID:33754040 | U2surp | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of U2SURP mRNA | CTD | PMID:25181051 | U2surp | Rat | bisphenol A | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of U2SURP protein | CTD | PMID:37567409 | U2surp | Rat | bisphenol A | decreases methylation | ISO | U2SURP (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of U2SURP gene | CTD | PMID:31601247 | U2surp | Rat | bisphenol A | increases expression | ISO | U2SURP (Homo sapiens) | 6480464 | bisphenol A results in increased expression of U2SURP mRNA | CTD | PMID:33670352 | U2surp | Rat | bisphenol A | decreases expression | ISO | U2surp (Mus musculus) | 6480464 | bisphenol A results in decreased expression of U2SURP mRNA | CTD | PMID:33221593 | U2surp | Rat | bisphenol A | increases expression | ISO | U2surp (Mus musculus) | 6480464 | bisphenol A results in increased expression of U2SURP mRNA | CTD | PMID:40036665 | U2surp | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of U2SURP mRNA | CTD | PMID:30816183|PMID:34947998 | U2surp | Rat | bisphenol AF | increases expression | ISO | U2SURP (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of U2SURP protein | CTD | PMID:34186270 | U2surp | Rat | Bisphenol B | increases expression | ISO | U2SURP (Homo sapiens) | 6480464 | bisphenol B results in increased expression of U2SURP protein | CTD | PMID:34186270 | U2surp | Rat | bisphenol F | increases expression | ISO | U2SURP (Homo sapiens) | 6480464 | bisphenol F results in increased expression of U2SURP protein | CTD | PMID:34186270 | U2surp | Rat | butanal | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of SR140 mRNA | CTD | PMID:26079696 | U2surp | Rat | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of U2SURP mRNA | CTD | PMID:19167457 | U2surp | Rat | caffeine | affects phosphorylation | ISO | U2SURP (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of U2SURP protein | CTD | PMID:35688186 | U2surp | Rat | carbon nanotube | decreases expression | ISO | U2surp (Mus musculus) | 6480464 | Nanotubes, Carbon results in decreased expression of U2SURP mRNA | CTD | PMID:25620056 | U2surp | Rat | chlorpyrifos | decreases expression | ISO | U2surp (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of U2SURP mRNA | CTD | PMID:37019170 | U2surp | Rat | clotrimazole | decreases expression | EXP | | 6480464 | Clotrimazole results in decreased expression of U2SURP mRNA | CTD | PMID:30047161 | U2surp | Rat | crocidolite asbestos | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Asbestos, Crocidolite results in decreased expression of U2SURP mRNA | CTD | PMID:29523930 | U2surp | Rat | DDE | increases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased expression of U2SURP mRNA | CTD | PMID:38568856 | U2surp | Rat | Dibutyl phosphate | affects expression | ISO | U2SURP (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of U2SURP mRNA | CTD | PMID:37042841 | U2surp | Rat | enzyme inhibitor | multiple interactions | ISO | U2SURP (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | U2surp | Rat | ethyl methanesulfonate | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of U2SURP mRNA | CTD | PMID:23649840 | U2surp | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of U2SURP mRNA | CTD | PMID:24136188 | U2surp | Rat | formaldehyde | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of U2SURP mRNA | CTD | PMID:23649840 | U2surp | Rat | FR900359 | affects phosphorylation | ISO | U2SURP (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of U2SURP protein | CTD | PMID:37730182 | U2surp | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of U2SURP mRNA | CTD | PMID:33387578 | U2surp | Rat | hinokiflavone | increases sumoylation | ISO | U2SURP (Homo sapiens) | 6480464 | hinokiflavone results in increased sumoylation of U2SURP protein | CTD | PMID:28884683 | U2surp | Rat | indometacin | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Indomethacin results in decreased expression of U2SURP mRNA | CTD | PMID:16984733 | U2surp | Rat | ivermectin | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of U2SURP protein | CTD | PMID:32959892 | U2surp | Rat | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of U2SURP mRNA | CTD | PMID:20080153 | U2surp | Rat | mercury dichloride | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Mercuric Chloride results in decreased expression of U2SURP mRNA | CTD | PMID:27188386 | U2surp | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of U2SURP mRNA | CTD | PMID:30467583 | U2surp | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of U2SURP mRNA | CTD | PMID:30047161 | U2surp | Rat | methyl methanesulfonate | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of U2SURP mRNA | CTD | PMID:23649840 | U2surp | Rat | methylmercury chloride | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of U2SURP mRNA | CTD | PMID:28001369 | U2surp | Rat | methylparaben | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | methylparaben results in decreased expression of U2SURP mRNA | CTD | PMID:31745603 | U2surp | Rat | mono(2-ethylhexyl) phthalate | increases expression | ISO | U2SURP (Homo sapiens) | 6480464 | mono-(2-ethylhexyl)phthalate results in increased expression of U2SURP mRNA | CTD | PMID:38685446 | U2surp | Rat | nickel dichloride | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | nickel chloride results in decreased expression of SR140 mRNA | CTD | PMID:17312168 | U2surp | Rat | nicotine | increases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Nicotine results in increased expression of U2SURP mRNA | CTD | PMID:16949557 | U2surp | Rat | paracetamol | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of U2SURP mRNA | CTD | PMID:21420995 | U2surp | Rat | pentanal | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | pentanal results in decreased expression of SR140 mRNA | CTD | PMID:26079696 | U2surp | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | U2surp (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of U2SURP mRNA | CTD | PMID:36331819 | U2surp | Rat | phenobarbital | decreases expression | ISO | U2surp (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of U2SURP mRNA | CTD | PMID:23091169 | U2surp | Rat | sodium arsenate | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | sodium arsenate results in decreased expression of U2SURP protein | CTD | PMID:38348393 | U2surp | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of U2SURP mRNA | CTD | PMID:30047161 | U2surp | Rat | sunitinib | increases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Sunitinib results in increased expression of U2SURP mRNA | CTD | PMID:31533062 | U2surp | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of U2SURP mRNA | CTD | PMID:33387578 | U2surp | Rat | trichostatin A | increases expression | ISO | U2SURP (Homo sapiens) | 6480464 | trichostatin A results in increased expression of SR140 mRNA | CTD | PMID:24935251 | U2surp | Rat | triphenyl phosphate | affects expression | ISO | U2SURP (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of U2SURP mRNA | CTD | PMID:37042841 | U2surp | Rat | troglitazone | decreases expression | ISO | U2surp (Mus musculus) | 6480464 | troglitazone results in decreased expression of U2SURP mRNA | CTD | PMID:28973697 | U2surp | Rat | tungsten | decreases expression | ISO | U2surp (Mus musculus) | 6480464 | Tungsten results in decreased expression of U2SURP mRNA | CTD | PMID:30912803 | U2surp | Rat | valproic acid | affects expression | ISO | U2SURP (Homo sapiens) | 6480464 | Valproic Acid affects the expression of U2SURP mRNA | CTD | PMID:25979313 | U2surp | Rat | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of U2SURP mRNA | CTD | PMID:29427782 | U2surp | Rat | valproic acid | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of U2SURP mRNA | CTD | PMID:23179753|PMID:27188386|PMID:28001369 | U2surp | Rat | vincristine | increases expression | ISO | U2SURP (Homo sapiens) | 6480464 | Vincristine results in increased expression of U2SURP mRNA | CTD | PMID:23649840 | U2surp | Rat | vorinostat | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | vorinostat results in decreased expression of U2SURP mRNA | CTD | PMID:27188386 | U2surp | Rat | Yessotoxin | decreases expression | ISO | U2SURP (Homo sapiens) | 6480464 | yessotoxin analog results in decreased expression of U2SURP mRNA | CTD | PMID:30679557 | | 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