Srsf7 (serine and arginine rich splicing factor 7) - Rat Genome Database

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Gene: Srsf7 (serine and arginine rich splicing factor 7) Rattus norvegicus
Analyze
Symbol: Srsf7
Name: serine and arginine rich splicing factor 7
RGD ID: 1307425
Description: Predicted to enable mRNA binding activity and protein domain specific binding activity. Predicted to be involved in RNA splicing; negative regulation of mRNA splicing, via spliceosome; and regulation of alternative mRNA splicing, via spliceosome. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in nuclear speck. Orthologous to human SRSF7 (serine and arginine rich splicing factor 7); PARTICIPATES IN spliceosome pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362687; MGC116344; serine/arginine-rich splicing factor 7; Sfrs7; splicing factor, arginine/serine-rich 7; splicing factor, arginine/serine-rich 7, 35kDa
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8620,564,035 - 20,571,205 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl620,564,044 - 20,571,212 (+)EnsemblGRCr8
mRatBN7.2614,811,775 - 14,818,968 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl614,811,808 - 14,818,965 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx615,110,001 - 15,116,053 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0615,432,426 - 15,438,373 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0614,928,701 - 14,934,648 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.062,879,312 - 2,886,505 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl62,880,518 - 2,886,465 (-)Ensemblrn6Rnor6.0
Rnor_5.062,856,205 - 2,863,398 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.463,101,772 - 3,104,433 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera614,488,763 - 14,494,964 (+)NCBICelera
RGSC_v3.163,098,484 - 3,104,488 (-)NCBI
Cytogenetic Map6q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-alpha-phellandrene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-bis(4-hydroxyphenyl)propionitrile  (EXP)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4,6-tribromophenol  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,6-dimethoxyphenol  (ISO)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
2-methylcholine  (ISO)
3',5'-cyclic UMP  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
alpha-phellandrene  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bucladesine  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium atom  (ISO)
clofibrate  (ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
enniatin  (ISO)
ethanol  (ISO)
folic acid  (ISO)
FR900359  (ISO)
furfural  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
GSK-J4  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
medroxyprogesterone acetate  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
nitrates  (ISO)
Nivalenol  (ISO)
nonanoic acid  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
pentachlorophenol  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
poly(I:C)  (EXP)
potassium dichromate  (ISO)
prednisolone  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium fluoride  (ISO)
succimer  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
toluene 2,4-diisocyanate  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
Yessotoxin  (ISO)
zinc sulfate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nuclear speck  (IBA)
nucleoplasm  (IEA,ISO)
nucleus  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors. Chen YI, etal., Nucleic Acids Res. 2007;35(12):3928-44. Epub 2007 May 30.
2. Regulation of alternative splicing of tau exon 10 by 9G8 and Dyrk1A. Ding S, etal., Neurobiol Aging. 2012 Jul;33(7):1389-99. doi: 10.1016/j.neurobiolaging.2010.11.021. Epub 2011 Jan 6.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Disturbed expression of splicing factors in renal cancer affects alternative splicing of apoptosis regulators, oncogenes, and tumor suppressors. Piekielko-Witkowska A, etal., PLoS One. 2010 Oct 27;5(10):e13690. doi: 10.1371/journal.pone.0013690.
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. The spliceosome: design principles of a dynamic RNP machine. Wahl MC, etal., Cell. 2009 Feb 20;136(4):701-18. doi: 10.1016/j.cell.2009.02.009.
11. Screening for genes up-regulated in 5/6 nephrectomized mouse kidney. Zhang H, etal., Kidney Int 1999 Aug;56(2):549-58.
Additional References at PubMed
PMID:8013463   PMID:10749975   PMID:12477932   PMID:15009664   PMID:18570454   PMID:20439489   PMID:22658674   PMID:22681889   PMID:23376485   PMID:24625528   PMID:25931508   PMID:33450132  
PMID:35352799  


Genomics

Comparative Map Data
Srsf7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8620,564,035 - 20,571,205 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl620,564,044 - 20,571,212 (+)EnsemblGRCr8
mRatBN7.2614,811,775 - 14,818,968 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl614,811,808 - 14,818,965 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx615,110,001 - 15,116,053 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0615,432,426 - 15,438,373 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0614,928,701 - 14,934,648 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.062,879,312 - 2,886,505 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl62,880,518 - 2,886,465 (-)Ensemblrn6Rnor6.0
Rnor_5.062,856,205 - 2,863,398 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.463,101,772 - 3,104,433 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera614,488,763 - 14,494,964 (+)NCBICelera
RGSC_v3.163,098,484 - 3,104,488 (-)NCBI
Cytogenetic Map6q12NCBI
SRSF7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38238,743,599 - 38,751,494 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl238,743,599 - 38,751,494 (-)Ensemblhg38GRCh38
GRCh37238,970,741 - 38,978,636 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36238,824,245 - 38,832,005 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34238,882,393 - 38,890,102NCBI
Celera238,811,778 - 38,819,677 (-)NCBICelera
Cytogenetic Map2p22.1NCBI
HuRef238,709,469 - 38,717,368 (-)NCBIHuRef
CHM1_1238,901,397 - 38,909,294 (-)NCBICHM1_1
T2T-CHM13v2.0238,752,384 - 38,760,281 (-)NCBIT2T-CHM13v2.0
Srsf7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391780,507,509 - 80,514,734 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1780,507,509 - 80,514,736 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381780,200,080 - 80,207,369 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1780,200,080 - 80,207,307 (-)Ensemblmm10GRCm38
MGSCv371780,599,420 - 80,606,625 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361780,108,406 - 80,115,615 (-)NCBIMGSCv36mm8
Celera1784,516,534 - 84,523,817 (-)NCBICelera
Cytogenetic Map17E3NCBI
cM Map1750.63NCBI
Srsf7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554416,416,952 - 6,423,074 (-)Ensembl
ChiLan1.0NW_0049554416,416,709 - 6,423,185 (-)NCBIChiLan1.0ChiLan1.0
SRSF7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21287,719,065 - 87,725,669 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A87,723,039 - 87,729,643 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A38,780,879 - 38,787,470 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A39,536,722 - 39,545,562 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A39,536,731 - 39,545,562 (-)EnsemblpanPan2panpan1.1
SRSF7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11730,809,743 - 30,816,269 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1730,809,951 - 30,816,218 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1730,622,954 - 30,632,513 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01731,462,098 - 31,471,656 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1731,464,014 - 31,471,605 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11730,684,547 - 30,694,100 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01730,754,277 - 30,763,838 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01730,967,454 - 30,977,016 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Srsf7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629241,047,290 - 41,054,162 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650812,475,661 - 12,481,501 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493650812,475,906 - 12,481,501 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRSF7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3101,603,707 - 101,613,237 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.13101,599,429 - 101,608,786 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23107,748,195 - 107,753,395 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SRSF7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11468,629,812 - 68,636,958 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604543,342,003 - 43,350,490 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Srsf7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473820,251,876 - 20,259,729 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473820,251,876 - 20,259,794 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Srsf7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1712,867,762 - 12,874,920 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Srsf7
56 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:259
Count of miRNA genes:184
Interacting mature miRNAs:204
Transcripts:ENSRNOT00000038448
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6197587946975879Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6197587946975879Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6144788383Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6197587946975879Rat
8693699Alc37Alcohol consumption QTL 372.60.224drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)61371716927053860Rat
2293706Bmd20Bone mineral density QTL 204.30.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)6125740059Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6197587946975879Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6323998948239989Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6323998948239989Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6140163351Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)61459947363457687Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6323998948239989Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)61608937261967788Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6323998948239989Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6197587946975879Rat
8693690Alc35Alcohol consumption QTL 352.20.606drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)61371716927053860Rat

Markers in Region
Sfrs7  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2614,813,066 - 14,814,241 (-)MAPPERmRatBN7.2
Rnor_6.062,884,039 - 2,885,213NCBIRnor6.0
Rnor_5.062,860,932 - 2,862,106UniSTSRnor5.0
RGSC_v3.463,102,017 - 3,103,191UniSTSRGSC3.4
Celera614,490,269 - 14,491,443UniSTS
Cytogenetic Map6q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001039035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC099175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM079490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM084661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM085512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM092264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000038448   ⟹   ENSRNOP00000035155
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl620,564,044 - 20,571,212 (+)Ensembl
mRatBN7.2 Ensembl614,811,809 - 14,817,762 (+)Ensembl
Rnor_6.0 Ensembl62,880,518 - 2,886,465 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093985   ⟹   ENSRNOP00000095518
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl620,564,045 - 20,571,196 (+)Ensembl
mRatBN7.2 Ensembl614,811,813 - 14,818,965 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094267   ⟹   ENSRNOP00000076395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl614,811,808 - 14,817,777 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097127   ⟹   ENSRNOP00000091604
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl620,564,046 - 20,571,196 (+)Ensembl
mRatBN7.2 Ensembl614,811,809 - 14,818,950 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098559   ⟹   ENSRNOP00000093012
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl620,564,410 - 20,566,633 (+)Ensembl
mRatBN7.2 Ensembl614,812,173 - 14,817,759 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118234   ⟹   ENSRNOP00000097772
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl620,564,044 - 20,569,760 (+)Ensembl
mRatBN7.2 Ensembl614,811,809 - 14,817,759 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000151137   ⟹   ENSRNOP00000104476
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl620,566,173 - 20,571,196 (+)Ensembl
RefSeq Acc Id: NM_001039035   ⟹   NP_001034124
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8620,564,052 - 20,569,999 (+)NCBI
mRatBN7.2614,811,815 - 14,817,762 (+)NCBI
Rnor_6.062,880,518 - 2,886,465 (-)NCBI
Rnor_5.062,856,205 - 2,863,398 (-)NCBI
RGSC_v3.463,101,772 - 3,104,433 (-)RGD
Celera614,488,763 - 14,494,964 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239642   ⟹   XP_006239704
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8620,564,035 - 20,569,999 (+)NCBI
mRatBN7.2614,811,775 - 14,818,968 (+)NCBI
Rnor_6.062,879,312 - 2,886,505 (-)NCBI
Rnor_5.062,856,205 - 2,863,398 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239643   ⟹   XP_006239705
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8620,564,035 - 20,569,999 (+)NCBI
mRatBN7.2614,811,775 - 14,818,968 (+)NCBI
Rnor_6.062,879,312 - 2,886,505 (-)NCBI
Rnor_5.062,856,205 - 2,863,398 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239644   ⟹   XP_006239706
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8620,564,035 - 20,569,999 (+)NCBI
mRatBN7.2614,811,775 - 14,818,968 (+)NCBI
Rnor_6.062,879,312 - 2,886,505 (-)NCBI
Rnor_5.062,856,205 - 2,863,398 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239645   ⟹   XP_006239707
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8620,564,035 - 20,569,999 (+)NCBI
mRatBN7.2614,811,775 - 14,818,968 (+)NCBI
Rnor_6.062,879,312 - 2,886,505 (-)NCBI
Rnor_5.062,856,205 - 2,863,398 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239646   ⟹   XP_006239708
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8620,564,035 - 20,569,999 (+)NCBI
mRatBN7.2614,811,775 - 14,818,968 (+)NCBI
Rnor_6.062,879,312 - 2,886,505 (-)NCBI
Rnor_5.062,856,205 - 2,863,398 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112457   ⟹   XP_038968385
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8620,564,035 - 20,566,742 (+)NCBI
mRatBN7.2614,811,775 - 14,814,525 (+)NCBI
RefSeq Acc Id: XM_039112458   ⟹   XP_038968386
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8620,566,083 - 20,571,205 (+)NCBI
mRatBN7.2614,813,850 - 14,818,968 (+)NCBI
RefSeq Acc Id: XM_063262046   ⟹   XP_063118116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8620,566,083 - 20,571,205 (+)NCBI
RefSeq Acc Id: XM_063262047   ⟹   XP_063118117
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8620,566,083 - 20,571,205 (+)NCBI
RefSeq Acc Id: XR_010052100
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8620,564,035 - 20,567,069 (+)NCBI
RefSeq Acc Id: NP_001034124   ⟸   NM_001039035
- UniProtKB: A0A8I6AFZ5 (UniProtKB/TrEMBL),   A6H9R6 (UniProtKB/TrEMBL),   A0A8I6ALL8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239708   ⟸   XM_006239646
- Peptide Label: isoform X5
- UniProtKB: A6H9R8 (UniProtKB/TrEMBL),   A0A8I6ALL8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239705   ⟸   XM_006239643
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006239707   ⟸   XM_006239645
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006239704   ⟸   XM_006239642
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006239706   ⟸   XM_006239644
- Peptide Label: isoform X3
- UniProtKB: D4A720 (UniProtKB/TrEMBL),   A6H9R7 (UniProtKB/TrEMBL),   A6H9R9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000035155   ⟸   ENSRNOT00000038448
RefSeq Acc Id: XP_038968385   ⟸   XM_039112457
- Peptide Label: isoform X7
- UniProtKB: A0A8I5YB97 (UniProtKB/TrEMBL),   A6H9S1 (UniProtKB/TrEMBL),   Q4KLJ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968386   ⟸   XM_039112458
- Peptide Label: isoform X8
Ensembl Acc Id: ENSRNOP00000097772   ⟸   ENSRNOT00000118234
Ensembl Acc Id: ENSRNOP00000095518   ⟸   ENSRNOT00000093985
Ensembl Acc Id: ENSRNOP00000076395   ⟸   ENSRNOT00000094267
Ensembl Acc Id: ENSRNOP00000093012   ⟸   ENSRNOT00000098559
Ensembl Acc Id: ENSRNOP00000091604   ⟸   ENSRNOT00000097127
RefSeq Acc Id: XP_063118117   ⟸   XM_063262047
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063118116   ⟸   XM_063262046
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000104476   ⟸   ENSRNOT00000151137
Protein Domains
CCHC-type   RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A720-F1-model_v2 AlphaFold D4A720 1-238 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694364
Promoter ID:EPDNEW_R4889
Type:single initiation site
Name:Srsf7_1
Description:serine and arginine rich splicing factor 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.062,886,473 - 2,886,533EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307425 AgrOrtholog
BioCyc Gene G2FUF-38521 BioCyc
Ensembl Genes ENSRNOG00000027360 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038448 ENTREZGENE
  ENSRNOT00000038448.7 UniProtKB/TrEMBL
  ENSRNOT00000093985.2 UniProtKB/TrEMBL
  ENSRNOT00000097127 ENTREZGENE
  ENSRNOT00000097127.2 UniProtKB/TrEMBL
  ENSRNOT00000098559.2 UniProtKB/TrEMBL
  ENSRNOT00000118234.2 UniProtKB/TrEMBL
  ENSRNOT00000151137 ENTREZGENE
  ENSRNOT00000151137.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
  Zinc finger, CCHC-type UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7382701 IMAGE-MGC_LOAD
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_RNP1 UniProtKB/TrEMBL
  SRSF UniProtKB/TrEMBL
  SRSF7_RRM UniProtKB/TrEMBL
  Znf_CCHC UniProtKB/TrEMBL
  Znf_CCHC_sf UniProtKB/TrEMBL
KEGG Report rno:362687 UniProtKB/TrEMBL
MGC_CLONE MGC:116344 IMAGE-MGC_LOAD
NCBI Gene 362687 ENTREZGENE
PANTHER RIBONUCLEOPROTEIN RB97D UniProtKB/TrEMBL
  SERINE/ARGININE RICH SPLICING FACTOR UniProtKB/TrEMBL
  SPLICING FACTOR, ARGININE_SERINE-RICH 1-RELATED UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
  zf-CCHC UniProtKB/TrEMBL
PhenoGen Srsf7 PhenoGen
PROSITE RRM UniProtKB/TrEMBL
  ZF_CCHC UniProtKB/TrEMBL
RatGTEx ENSRNOG00000027360 RatGTEx
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
  SSF57756 UniProtKB/TrEMBL
UniProt A0A8I5YB97 ENTREZGENE
  A0A8I6AEZ9_RAT UniProtKB/TrEMBL
  A0A8I6AFZ5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALL8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GMN8_RAT UniProtKB/TrEMBL
  A0ABK0LRC9_RAT UniProtKB/TrEMBL
  A6H9R6 ENTREZGENE, UniProtKB/TrEMBL
  A6H9R7 ENTREZGENE, UniProtKB/TrEMBL
  A6H9R8 ENTREZGENE, UniProtKB/TrEMBL
  A6H9R9 ENTREZGENE, UniProtKB/TrEMBL
  A6H9S1 ENTREZGENE, UniProtKB/TrEMBL
  D4A720 ENTREZGENE, UniProtKB/TrEMBL
  Q4KLJ1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-15 Srsf7  serine and arginine rich splicing factor 7  Srsf7  serine/arginine-rich splicing factor 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-01 Srsf7  serine/arginine-rich splicing factor 7  Sfrs7  splicing factor, arginine/serine-rich 7, 35kDa  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-22 Sfrs7  splicing factor, arginine/serine-rich 7, 35kDa  Srsf7  serine/arginine-rich splicing factor 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-13 Srsf7  serine/arginine-rich splicing factor 7  Sfrs7  splicing factor, arginine/serine-rich 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-04-27 Sfrs7  splicing factor, arginine/serine-rich 7  Sfrs7  splicing factor, arginine/serine-rich 7, 35kDa  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-09-20 Sfrs7  splicing factor, arginine/serine-rich 7, 35kDa  Srsf7  serine/arginine-rich splicing factor 7   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-09-14 Srsf7  serine/arginine-rich splicing factor 7   Sfrs7  splicing factor, arginine/serine-rich 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Sfrs7  splicing factor, arginine/serine-rich 7  Sfrs7_predicted  splicing factor, arginine/serine-rich 7 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Sfrs7_predicted  splicing factor, arginine/serine-rich 7 (predicted)      Symbol and Name status set to approved 70820 APPROVED