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Gene: Pbx3 (PBX homeobox 3) Rattus norvegicus

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Symbol:

Pbx3

Name:

PBX homeobox 3

RGD ID:

1307198

Description:

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including eye development; nervous system development; and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human PBX3 (PBX homeobox 3); INTERACTS WITH 17beta-estradiol; 3,4-methylenedioxymethamphetamine; benzo[a]pyrene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC102551296; LOC311876; pre B-cell leukemia transcription factor 3; pre-B-cell leukemia homeobox 3; pre-B-cell leukemia transcription factor 3; pre-B-cell leukemia transcription factor 3-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PBX3 (PBX homeobox 3)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Pbx3 (pre B cell leukemia homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pbx3 (PBX homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PBX3 (PBX homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PBX3 (PBX homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pbx3 (PBX homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PBX3 (PBX homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PBX3 (PBX homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pbx3 (PBX homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Pbx3 (PBX homeobox 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PBX1 (PBX homeobox 1)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	PBX3 (PBX homeobox 3)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pbx3 (pre B cell leukemia homeobox 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pbx3 (pre B cell leukemia homeobox 3)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pbx1b (pre-B-cell leukemia homeobox 1b)	Alliance	DIOPT (InParanoid\|OMA\|OrthoInspector\|SonicParanoid)
Danio rerio (zebrafish):	pbx1a (pre-B-cell leukemia homeobox 1a)	Alliance	DIOPT (InParanoid\|OMA\|OrthoInspector\|SonicParanoid)
Danio rerio (zebrafish):	pbx3b (pre-B-cell leukemia homeobox 3b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	pbx3b (pre-B-cell leukemia homeobox 3b)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	exd	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	exd	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ceh-20	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ceh-20	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ceh-40	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	pbx3	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ceh-60	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	37,886,241 - 38,079,956 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	37,886,687 - 38,079,895 (-)	Ensembl				GRCr8
mRatBN7.2	3	17,488,691 - 17,682,412 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	17,488,693 - 17,682,791 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	20,557,559 - 20,750,825 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	29,142,610 - 29,335,881 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	27,395,628 - 27,589,698 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	3	35,432,511 - 35,626,591 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	3	42,399,339 - 42,592,130 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	3	34,297,998 - 34,490,904 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	3	15,505,145 - 15,698,015 (-)	NCBI		F344_StmMcwi
Rnor_6.0	3	13,241,031 - 13,436,084 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	13,182,024 - 13,525,983 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	18,569,183 - 18,763,413 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	13,200,261 - 13,405,859 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	12,211,343 - 12,404,425 (-)	NCBI		Celera
RGSC_v3.1	3	13,096,449 - 13,311,087 (-)	NCBI
Cytogenetic Map	3	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Congenital Heart Defects, Multiple Types (ISO)

esophagus squamous cell carcinoma (ISO)

X-linked cone-rod dystrophy 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

3,4-methylenedioxymethamphetamine (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-fluorouracil (ISO)

aflatoxin B1 (ISO)

aflatoxin M1 (ISO)

all-trans-retinoic acid (ISO)

arsenous acid (ISO)

azathioprine (ISO)

benzo[a]pyrene (EXP,ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bortezomib (ISO)

butanal (ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

cisplatin (ISO)

cobalt dichloride (EXP)

cocaine (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP,ISO)

diethyl phthalate (ISO)

diisobutyl phthalate (ISO)

diisononyl phthalate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

folic acid (ISO)

fulvestrant (ISO)

gentamycin (EXP)

hexadecanoic acid (ISO)

indometacin (ISO)

ketamine (EXP)

L-methionine (ISO)

lead diacetate (ISO)

methapyrilene (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

tamoxifen (ISO)

temozolomide (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (ISO)

thapsigargin (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

toluene (EXP)

topotecan (EXP)

trichostatin A (ISO)

triclosan (ISO)

trovafloxacin (ISO)

uranium atom (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adult locomotory behavior (ISO)

dorsal spinal cord development (ISO)

neuron development (ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of DNA-templated transcription (IEA)

regulation of respiratory gaseous exchange by nervous system process (ISO)

regulation of transcription by RNA polymerase II (IEA)

respiratory gaseous exchange by respiratory system (ISO)

Cellular Component

nucleus (IEA,ISO)

transcription regulator complex (IEA,ISO)

Molecular Function

DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA,ISO)

DNA-binding transcription factor activity (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA,ISO)

sequence-specific DNA binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Non-synonymous variants in pre-B cell leukemia homeobox (PBX) genes are associated with congenital heart defects.	Arrington CB, etal., Eur J Med Genet. 2012 Apr;55(4):235-7. doi: 10.1016/j.ejmg.2012.02.002. Epub 2012 Feb 23.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Downregulation of lncRNA-HEIH curbs esophageal squamous cell carcinoma progression by modulating miR-4458/PBX3.	Wang D, etal., Thorac Cancer. 2020 Jul;11(7):1963-1971. doi: 10.1111/1759-7714.13489. Epub 2020 May 25.

Additional References at PubMed

PMID:10381567	PMID:10842069	PMID:15466398	PMID:15527896	PMID:16847320	PMID:18155191	PMID:33389498

Genomics

Comparative Map Data

Pbx3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	37,886,241 - 38,079,956 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	37,886,687 - 38,079,895 (-)	Ensembl				GRCr8
mRatBN7.2	3	17,488,691 - 17,682,412 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	17,488,693 - 17,682,791 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	20,557,559 - 20,750,825 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	29,142,610 - 29,335,881 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	27,395,628 - 27,589,698 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	3	35,432,511 - 35,626,591 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	3	42,399,339 - 42,592,130 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	3	34,297,998 - 34,490,904 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	3	15,505,145 - 15,698,015 (-)	NCBI		F344_StmMcwi
Rnor_6.0	3	13,241,031 - 13,436,084 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	13,182,024 - 13,525,983 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	18,569,183 - 18,763,413 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	13,200,261 - 13,405,859 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	12,211,343 - 12,404,425 (-)	NCBI		Celera
RGSC_v3.1	3	13,096,449 - 13,311,087 (-)	NCBI
Cytogenetic Map	3	p11	NCBI

PBX3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	125,747,373 - 125,967,377 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	125,746,737 - 125,967,377 (+)	Ensembl			hg38	GRCh38
GRCh37	9	128,509,652 - 128,729,656 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	127,549,487 - 127,769,477 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	9	125,589,286 - 125,808,921	NCBI
Celera	9	99,158,741 - 99,384,104 (+)	NCBI		Celera
Cytogenetic Map	9	q33.3	NCBI
HuRef	9	98,122,353 - 98,347,071 (+)	NCBI		HuRef
CHM1_1	9	128,660,292 - 128,880,307 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	137,947,324 - 138,172,756 (+)	NCBI		T2T-CHM13v2.0

Pbx3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	34,061,469 - 34,264,168 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	34,061,469 - 34,263,154 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	34,171,457 - 34,372,045 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	34,171,457 - 34,373,142 (-)	Ensembl			mm10	GRCm38
MGSCv37	2	34,027,429 - 34,227,556 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	33,993,918 - 34,194,045 (-)	NCBI		MGSCv36	mm8
Celera	2	33,869,694 - 34,069,148 (-)	NCBI		Celera
Cytogenetic Map	2	B	NCBI
cM Map	2	22.84	NCBI

Pbx3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	2,419,029 - 2,627,607 (-)	Ensembl
ChiLan1.0	NW_004955419	2,419,081 - 2,624,299 (-)	NCBI	ChiLan1.0	ChiLan1.0

PBX3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	13,387,710 - 13,609,960 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	13,390,056 - 13,612,138 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	96,867,140 - 97,089,205 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	125,379,110 - 125,599,634 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	125,379,489 - 125,598,178 (+)	Ensembl			panPan2	panpan1.1

PBX3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	57,198,531 - 57,429,820 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	57,199,812 - 57,429,811 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	56,399,623 - 56,630,129 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	58,119,354 - 58,350,418 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	58,119,626 - 58,337,153 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	56,877,592 - 57,108,518 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	57,193,844 - 57,424,560 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	57,284,917 - 57,516,098 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pbx3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	194,010,931 - 194,218,090 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	13,779,454 - 13,987,722 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936487	13,779,999 - 13,986,617 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PBX3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	266,382,640 - 266,610,640 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	266,383,311 - 266,610,646 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	300,208,202 - 300,433,688 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PBX3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	12,174,407 - 12,400,184 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666079	3,721,016 - 3,948,699 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pbx3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	9,352,563 - 9,553,984 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624760	9,352,759 - 9,555,211 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pbx3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	5	1,260,615 - 1,453,402 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pbx3
1475 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	388
Count of miRNA genes:	213
Interacting mature miRNAs:	246
Transcripts:	ENSRNOT00000029600
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358357	Srcrtb1	Stress Responsive Cort Basal QTL 1	6.36	0.002	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	29056275	47904329	Rat
6893355	Bw101	Body weight QTL 101	0.4	0.38	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
11528620	Bss113	Bone structure and strength QTL 113	9.75	2e-10	femur morphology trait (VT:0000559)	femoral neck width (CMO:0001695)	3	36888342	39639105	Rat
634306	Bp140	Blood pressure QTL 140	3.3	0.0013	arterial blood pressure trait (VT:2000000)	body weight (CMO:0000012)	3	37772258	55937853	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	28625339	67641995	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	35403199	97383526	Rat
1298526	Arunc3	Aerobic running capacity QTL 3	2.2		exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	3	6125437	51125437	Rat
8693641	Alc30	Alcohol consumption QTL 30	2	0.739	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	3	30832384	44921701	Rat
1558657	Cm43	Cardiac mass QTL 43	6.6	3e-08	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	22677150	50766390	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	15272348	60272348	Rat
1300169	Bp177	Blood pressure QTL 177	2.96		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	3	36425116	81425116	Rat
6893363	Bw105	Body weight QTL 105	2.6	0.0036	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
631831	Alc8	Alcohol consumption QTL 8	2.7		consumption behavior trait (VT:0002069)	calculated ethanol drink intake rate (CMO:0001615)	3	37796919	53640235	Rat
1558647	Cm46	Cardiac mass QTL 46	5.4	0.0000055	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	22677150	50766390	Rat
4889966	Bss95	Bone structure and strength QTL 95	4.4		tibia area (VT:1000281)	tibia-fibula cross-sectional area (CMO:0001718)	3	37796919	82796919	Rat
10450811	Scl73	Serum cholesterol level QTL 73	4.7	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
2292615	Ept17	Estrogen-induced pituitary tumorigenesis QTL 17	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6556347	51556347	Rat
10450808	Scl72	Serum cholesterol level QTL 72	4.4	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
1558654	Bw56	Body weight QTL 56	4.5	0.0000171	body mass (VT:0001259)	body weight (CMO:0000012)	3	5766390	50766390	Rat
10450806	Scl71	Serum cholesterol level QTL 71	5.8	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	2904329	47904329	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	36721849	110333156	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
631676	Cm8	Cardiac mass QTL 8	7.03	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	3	37363734	82363734	Rat
631679	Cm10	Cardiac mass QTL 10	7.34	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	6556347	51556347	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	36101403	81101403	Rat
70203	Gcr2	Gastric cancer resistance QTL 2	2.6		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	3	29056275	47904329	Rat
70202	Alc19	Alcohol consumption QTL 19	2.5		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	3	37796919	47904329	Rat
2312664	Scl62	Serum cholesterol level QTL 62		0.05	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	37796919	59119581	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat
1358185	Ept6	Estrogen-induced pituitary tumorigenesis QTL 6	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6556347	51556347	Rat

Markers in Region

D3Chm7

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	17,600,282 - 17,600,509 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	13,352,601 - 13,352,827	NCBI	Rnor6.0
Rnor_5.0	3	18,680,823 - 18,681,049	UniSTS	Rnor5.0
RGSC_v3.4	3	13,312,546 - 13,312,772	UniSTS	RGSC3.4
RGSC_v3.4	3	13,312,545 - 13,312,772	RGD	RGSC3.4
Celera	3	12,322,409 - 12,322,635	UniSTS
Cytogenetic Map	3	p11	UniSTS

RH133967

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	17,672,538 - 17,672,744 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	14,159,612 - 14,159,817	NCBI	Rnor6.0
Rnor_6.0	3	13,426,211 - 13,426,416	NCBI	Rnor6.0
Rnor_5.0	3	18,753,576 - 18,753,781	UniSTS	Rnor5.0
Rnor_5.0	3	19,478,517 - 19,478,722	UniSTS	Rnor5.0
RGSC_v3.4	3	13,396,073 - 13,396,278	UniSTS	RGSC3.4
Celera	3	12,394,614 - 12,394,819	UniSTS
Cytogenetic Map	3	p11	UniSTS

G07093

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	17,489,211 - 17,489,318 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	13,241,552 - 13,241,658	NCBI	Rnor6.0
Rnor_5.0	3	18,569,704 - 18,569,810	UniSTS	Rnor5.0
RGSC_v3.4	3	13,200,336 - 13,200,442	UniSTS	RGSC3.4
Celera	3	12,211,418 - 12,211,524	UniSTS
Cytogenetic Map	3	p11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	355	192	11	143	80	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107834	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105260	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000029600 ⟹ ENSRNOP00000029846

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	17,488,693 - 17,682,303 (-)	Ensembl
Rnor_6.0 Ensembl	3	13,240,999 - 13,435,979 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000082036 ⟹ ENSRNOP00000075035

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	37,890,623 - 38,079,895 (-)	Ensembl
mRatBN7.2 Ensembl	3	17,494,240 - 17,682,350 (-)	Ensembl
Rnor_6.0 Ensembl	3	13,182,024 - 13,525,983 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096937 ⟹ ENSRNOP00000087541

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	37,886,687 - 38,079,895 (-)	Ensembl
mRatBN7.2 Ensembl	3	17,488,954 - 17,682,323 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000111698 ⟹ ENSRNOP00000082471

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	17,488,693 - 17,682,791 (-)	Ensembl

RefSeq Acc Id:

NM_001107834 ⟹ NP_001101304

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	37,886,687 - 38,079,895 (-)	NCBI
mRatBN7.2	3	17,489,137 - 17,682,350 (-)	NCBI
Dahl_SR_JrHsd	3	35,432,511 - 35,626,591 (-)	NCBI
Lyon_Normotensive	3	42,399,339 - 42,592,130 (-)	NCBI
Lyon_Hypertensive	3	34,297,998 - 34,490,904 (-)	NCBI
F344_StmMcwi	3	15,505,145 - 15,698,015 (-)	NCBI
Rnor_6.0	3	13,241,477 - 13,436,022 (-)	NCBI
Rnor_5.0	3	18,569,183 - 18,763,413 (-)	NCBI
RGSC_v3.4	3	13,200,261 - 13,405,859 (-)	RGD
Celera	3	12,211,343 - 12,404,425 (-)	RGD

Sequence:

show sequence

CTTCGCCTCCGCCGCCGCCGCCCGCTCCCGCCCGCGCGCGGCGGGATGGACGATCAATCCAGGA
TGCTGCAGACTCTGGCCGGGGTGAACCTGGCCGGCCACTCGGTCCAAGGGGGTATGGCTCTGCC
GCCTCCCCCTCACGGCCACGAAGGGGCGGACGGCGACGGCAGGAAGCAGGACATCGGCGACATC
CTCCACCAGATCATGACCATCACCGACCAGAGCTTGGACGAGGCGCAAGCAAAGAAACATGCTC
TGAACTGTCACAGAATGAAACCGGCGCTCTTCAGCGTCTTGTGTGAGATCAAAGAGAAAACAGG
TCTCAGCATCAGAGGAGCCCAGGAGGAAGACCCTCCCGACCCCCAGCTAATGAGACTGGACAAT
ATGCTTTTGGCAGAAGGGGTTTCAGGTCCTGAGAAAGGTGGGGGATCGGCGGCAGCAGCTGCAG
CCGCGGCAGCCTCTGGAGGTTCTTCAGATAACTCTATTGAACACTCAGATTACAGAGCCAAATT
GACCCAGATCAGACAAATCTATCACACAGAACTGGAGAAATATGAACAGGCATGTAATGAATTC
ACAACACACGTGATGAACCTTCTCCGAGAACAGAGTAGAACGCGTCCCATTTCCCCGAAAGAGA
TCGAAAGGATGGTGGGCATCATCCACAGGAAGTTTAGCTCCATCCAAATGCAGCTCAAGCAGAG
CACGTGTGAAGCAGTCATGATTTTAAGATCAAGGTTCCTTGATGCCAGACGGAAAAGGCGTAAC
TTCAGTAAACAGGCTACAGAAATCTTGAATGAATATTTTTACTCACACCTCAGCAACCCCTACC
CCAGTGAAGAAGCCAAAGAGGAGCTGGCCAAGAAATGCAGCATCACAGTATCACAGGTATCCAA
CTGGTTTGGCAACAAACGAATCAGGTACAAGAAGAACATCGGCAAATTTCAAGAGGAGGCCAAT
CTCTATGCTGCAAAAACAGCCGTGACAGCCGCACACGCAGTGGCCGCAGCCGTGCAGAACAACC
AGACCAACTCACCCACCACGCCAAACTCTGGTTCTTCTGGTTCTTTTAACCTCCCAAATTCTGG
GGACATGTTCATGAACATGCAGAGTCTGAATGGGGATTCTTACCAAGGGTCCCAAGTCGGAGCC
AATGTGCAGTCACAGGTGGATACCCTCCGTCATGTTATCAATCAGACGGGAGGCTACAGTGACG
GCCTTGGAGCAAACTCACTGTACAGTCCGCATAACTTAAACGCTAATGGAGGCTGGCAGGACGC
AACAACTCCATCTTCTGTGACTTCTCCTACGGAAGGCCCGGGCAGCGTGCACTCGGATACCTCT
AACTAATCCTGGCCTCTCCCAGCTGTCATGCCTTGACAAGCGCATTCGGAGCAATAGGAGGAGG
AGGGAAGCGTTTTGTAACCCACCACCTACAGCTTTACTGTAAACCCTGTCTTCTTAGAGAACTC
GGGAAACCTGTTTTTTAAGGAATCATAACCATTTGTATTTAAACTTAAGACACACGTTTAAAGG
AAAGCACTTTATCCGATTAGGCCGAGACGTAACATTGTTGACAGTTCTTAACTGTCTCATCCTA
ATTTATTATTACATTTTACAGTAATGGTTCCACAGTTGCCAGTTCCTTGGCCTTAAGGGTAAGA
AGTACCATCTATGCTAGACCCCAATTATAGAGCAGGCAAGGTTCACCCTGCCTACGCTGAGCCC
TGGCGGATTTCCATGCAGGCTCTCATCGTTCTCACGTCACGGATGGGCTTGGAGGGAAGGCGAT
GTCTGCCTGTCTTCTTAAGGAAGGCATTTCAGAACTTCCCTCGCCATGTTTGTGTTGCCATCTC
TTATGTTGTAATTAGGTCAAAGACTGGTGGCCTCCTTTCTCCCTCTGAAGTACCAGAGCCCGGA
GTCTGCGCTAATGAGACCATGGATCCAGATTGCCCTGAGATGAAGATCTTGCTGCTACAGAGGT
GAAAACAAGACCTGTCTGGGGTTTGACCGTGTGCGCTGGGTGCTGCACAGACTTGTCAAGGTGT
GCTCTTCCTCTGGGCAGCCTGGAAAGGCCCTGCTCTCTGGAGTGCTGTATATAGTGTAGCAAAA
GAGTATTTATACATCCCACCAATCAAAACACAGCTTTATTACCTCATGCGAACTCATACAAACC
AATAGAATCCCAACATGTTCTGTAGCTTAGAGCGCTCACTTACTACCTCTGAACAATACTCACG
CTGTAGTTCGTCTCTTTCTTATCTTTTTGCATCTTGTAATTAACTCTTTGTTTCCCTTCACAAA
ATGTAATGTACATT

hide sequence

RefSeq Acc Id:

XM_006233975 ⟹ XP_006234037

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	37,887,688 - 38,079,956 (-)	NCBI
mRatBN7.2	3	17,489,117 - 17,682,412 (-)	NCBI
Rnor_6.0	3	13,241,031 - 13,436,084 (-)	NCBI
Rnor_5.0	3	18,569,183 - 18,763,413 (-)	NCBI

Sequence:

show sequence

CTCCCCCTCCCCCTAACCCCTCCTTTCTTCTCCTCCCTCGCCGCCGCCGCCGCCGCCTCAGCCT
TCGCCTCCGCCGCCGCCGCCCGCTCCCGCCCGCGCGCGGCGGGATGGACGATCAATCCAGGATG
CTGCAGACTCTGGCCGGGGTGAACCTGGCCGGCCACTCGGTCCAAGGGGGTATGGCTCTGCCGC
CTCCCCCTCACGGCCACGAAGGGGCGGACGGCGACGGCAGGAAGCAGGACATCGGCGACATCCT
CCACCAGATCATGACCATCACCGACCAGAGCTTGGACGAGGCGCAAGCAAAGAAACATGCTCTG
AACTGTCACAGAATGAAACCGGCGCTCTTCAGCGTCTTGTGTGAGATCAAAGAGAAAACAGGTC
TCAGCATCAGAGGAGCCCAGGAGGAAGACCCTCCCGACCCCCAGCTAATGAGACTGGACAATAT
GCTTTTGGCAGAAGGGGTTTCAGGTCCTGAGAAAGGTGGGGGATCGGCGGCAGCAGCTGCAGCC
GCGGCAGCCTCTGGAGGTTCTTCAGATAACTCTATTGAACACTCAGATTACAGAGCCAAATTGA
CCCAGATCAGACAAATCTATCACACAGAACTGGAGAAATATGAACAGGCATGTAATGAATTCAC
AACACACGTGATGAACCTTCTCCGAGAACAGAGTAGAACGCGTCCCATTTCCCCGAAAGAGATC
GAAAGGATGGTGGGCATCATCCACAGGAAGTTTAGCTCCATCCAAATGCAGCTCAAGCAGAGCA
CGTGTGAAGCAGTCATGATTTTAAGATCAAGGTTCCTTGATGCCAGACGGAAAAGGCGTAACTT
CAGTAAACAGGCTACAGAAATCTTGAATGAATATTTTTACTCACACCTCAGCAACCCCTACCCC
AGTGAAGAAGCCAAAGAGGAGCTGGCCAAGAAATGCAGCATCACAGTATCACAGGTATCCAACT
GGTTTGGCAACAAACGAATCAGGTACAAGAAGAACATCGGCAAATTTCAAGAGGAGGCCAATCT
CTATGCTGCAAAAACAGCCGTGACAGCCGCACACGCAGTGGCCGCAGCCGTGCAGAACAACCAG
ACCAACTCACCCACCACGCCAAACTCTGGTGGATACCCTCCGTCATGTTATCAATCAGACGGGA
GGCTACAGTGACGGCCTTGGAGCAAACTCACTGTACAGTCCGCATAACTTAAACGCTAATGGAG
GCTGGCAGGACGCAACAACTCCATCTTCTGTGACTTCTCCTACGGAAGGCCCGGGCAGCGTGCA
CTCGGATACCTCTAACTAATCCTGGCCTCTCCCAGCTGTCATGCCTTGACAAGCGCATTCGGAG
CAATAGGAGGAGGAGGGAAGCGTTTTGTAACCCACCACCTACAGCTTTACTGTAAACCCTGTCT
TCTTAGAGAACTCGGGAAACCTGTTTTTTAAGGAATCATAACCATTTGTATTTAAACTTAAGAC
ACACGTTTAAAGGAAAGCACTTTATCCGATTAGGCCGAGACGTAACATTGTTGACAGTTCTTAA
CTGTCTCATCCTAATTTATTATTACATTTTACAGTAATGGTTCCACAGTTGCCAGTTCCTTGGC
CTTAAGGGTAAGAAGTACCATCTATGCTAGACCCCAATTATAGAGCAGGCAAGGTTCACCCTGC
CTACGCTGAGCCCTGGCGGATTTCCATGCAGGCTCTCATCGTTCTCACGTCACGGATGGGCTTG
GAGGGAAGGCGATGTCTGCCTGTCTTCTTAAGGAAGGCATTTCAGAACTTCCCTCGCCATGTTT
GTGTTGCCATCTCTTATGTTGTAATTAGGTCAAAGACTGGTGGCCTCCTTTCTCCCTCTGAAGT
ACCAGAGCCCGGAGTCTGCGCTAATGAGACCATGGATCCAGATTGCCCTGAGATGAAGATCTTG
CTGCTACAGAGGTGAAAACAAGACCTGTCTGGGGTTTGACCGTGTGCGCTGGGTGCTGCACAGA
CTTGTCAAGGTGTGCTCTTCCTCTGGGCAGCCTGGAAAGGCCCTGCTCTCTGGAGTGCTGTATA
TAGTGTAGCAAAAGAGTATTTATACATCCCACCAATCAAAACACAGCTTTATTACCTCATGCGA
ACTCATACAAACCAATAGAATCCCAACATGTTCTGTAGCTTAGAGCGCTCACTTACTACCTCTG
AACAATACTCACGCTGTAGTTCGTCTCTTTCTTATCTTTTTGCATCTTGTAATTAACTCTTTGT
TTCCCTTCACAAAATGTAATGTACATTGTAATCTTTTAAAAGAAAACTCAGGGTTGCATTTGCA
ACCCTTAAAAAGCCCAGATCGGCAACATTGGGTCTGACTCCTAACACGGACCATCCCAGCTGTT
GTAAATACTGAGACGCGTGTTGAATGTTCTTCATCTTGTTACTAATCCATATGAAGAAAAAGGA
AAAAAGAAAAAAAAAAAGGCGGGTTCTTGTGATGCGTTCAGATTCAGTACTCAGCACTGTACAT
TTCACCCTGTGTGGCGGGCCCTCTCCTCCTCTTTTTGTATTGTATGCGATTCTGAAACTGACTG
GGTCGTGACAATAATTCGTGGCGGTGATTCTGATGTATTAAAAGCGTTCCGTGTTCCTTTCTAC
TGGCTCACACCCTGGATTGAAAAGTCTTCCTTGTGGTAGTTATATGTAGTTTCAAACATGAATA
AACTTTGCTTTCCTGATTAAACCTA

hide sequence

RefSeq Acc Id:

XM_039105260 ⟹ XP_038961188

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	37,886,241 - 38,079,715 (-)	NCBI
mRatBN7.2	3	17,488,691 - 17,682,153 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101304	(Get FASTA)	NCBI Sequence Viewer
	XP_006234037	(Get FASTA)	NCBI Sequence Viewer
	XP_038961188	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL93176	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000075035
	ENSRNOP00000075035.3
	ENSRNOP00000087541
	ENSRNOP00000087541.2

RefSeq Acc Id:

NP_001101304 ⟸ NM_001107834

- UniProtKB:

D4AB31 (UniProtKB/TrEMBL), A6JUC0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGDGRKQDIGDILHQIMTITDQSLDEA
QAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGGG
SAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTR
PISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYS
HLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVA
AAVQNNQTNSPTTPNSGSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQ
TGGYSDGLGANSLYSPHNLNANGGWQDATTPSSVTSPTEGPGSVHSDTSN

hide sequence

RefSeq Acc Id:	XP_006234037 ⟸ XM_006233975
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AGR6 (UniProtKB/TrEMBL), A0A0G2K9K8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGDGRKQDIGDILHQIMTITDQSLDEA QAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGGG SAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTR PISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYS HLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVA AAVQNNQTNSPTTPNSGGYPPSCYQSDGRLQ hide sequence

Ensembl Acc Id:

ENSRNOP00000075035 ⟸ ENSRNOT00000082036

Ensembl Acc Id:

ENSRNOP00000029846 ⟸ ENSRNOT00000029600

RefSeq Acc Id:	XP_038961188 ⟸ XM_039105260
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000082471 ⟸ ENSRNOT00000111698

Ensembl Acc Id:

ENSRNOP00000087541 ⟸ ENSRNOT00000096937

Protein Domains

Homeobox PBC

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4AB31-F1-model_v2	AlphaFold	D4AB31	1-434	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692003

Promoter ID:

EPDNEW_R2528

Type:

single initiation site

Name:

Pbx3_1

Description:

PBX homeobox 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	13,436,058 - 13,436,118	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307198	AgrOrtholog
BioCyc Gene	G2FUF-50090	BioCyc
Ensembl Genes	ENSRNOG00000022162	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000082036	ENTREZGENE
	ENSRNOT00000082036.3	UniProtKB/TrEMBL
	ENSRNOT00000096937	ENTREZGENE
	ENSRNOT00000096937.2	UniProtKB/TrEMBL
Gene3D-CATH	Homeodomain-like	UniProtKB/TrEMBL
InterPro	Homeobox	UniProtKB/TrEMBL
	Homeobox_CS	UniProtKB/TrEMBL
	Homeobox_KN_domain	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
	PBX	UniProtKB/TrEMBL
	TALE_homeobox	UniProtKB/TrEMBL
KEGG Report	rno:311876	UniProtKB/TrEMBL
NCBI Gene	311876	ENTREZGENE
PANTHER	HOMEOBOX PROTEIN TRANSCRIPTION FACTORS	UniProtKB/TrEMBL
Pfam	Homeobox_KN	UniProtKB/TrEMBL
	PBC	UniProtKB/TrEMBL
PhenoGen	Pbx3	PhenoGen
PROSITE	HOMEOBOX_1	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
	PBC	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000022162	RatGTEx
SMART	HOX	UniProtKB/TrEMBL
Superfamily-SCOP	Homeodomain_like	UniProtKB/TrEMBL
UniProt	A0A0G2K9K8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AGR6	ENTREZGENE, UniProtKB/TrEMBL
	A6JUC0	ENTREZGENE, UniProtKB/TrEMBL
	D4AB31	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Pbx3	PBX homeobox 3	LOC102551296	pre-B-cell leukemia transcription factor 3-like	Data merged from RGD:7560948	737654	PROVISIONAL
2016-05-26	Pbx3	PBX homeobox 3	Pbx3	pre-B-cell leukemia homeobox 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-12-17	LOC102551296	pre-B-cell leukemia transcription factor 3-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-10-30	Pbx3	pre-B-cell leukemia homeobox 3	Pbx3	pre B-cell leukemia transcription factor 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Pbx3	pre B-cell leukemia transcription factor 3	Pbx3_predicted	pre B-cell leukemia transcription factor 3 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Pbx3_predicted	pre B-cell leukemia transcription factor 3 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

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Imported Disease Annotations - ClinVar