Lmo2 (LIM domain only 2) - Rat Genome Database

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Pathways
Gene: Lmo2 (LIM domain only 2) Rattus norvegicus
Analyze
Symbol: Lmo2
Name: LIM domain only 2
RGD ID: 1307101
Description: Predicted to enable several functions, including DNA-binding transcription factor binding activity; identical protein binding activity; and transcription coactivator activity. Predicted to contribute to DNA binding activity. Predicted to be involved in negative regulation of erythrocyte differentiation and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within embryonic hemopoiesis. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Orthologous to human LMO2 (LIM domain only 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362176; MGC124678; rhombotin-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83110,810,162 - 110,832,895 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3110,809,912 - 110,833,075 (+)EnsemblGRCr8
mRatBN7.2390,355,234 - 90,377,970 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl390,365,883 - 90,377,953 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx393,848,260 - 93,870,995 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03102,447,339 - 102,470,072 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03100,277,857 - 100,300,590 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0393,909,156 - 93,931,888 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl393,909,156 - 93,931,871 (+)Ensemblrn6Rnor6.0
Rnor_5.03100,549,307 - 100,572,039 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4389,356,199 - 89,367,641 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera389,416,677 - 89,439,412 (+)NCBICelera
RGSC_v3.1389,252,944 - 89,263,314 (+)NCBI
Cytogenetic Map3q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
cisplatin  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
flusilazole  (EXP)
furan  (EXP)
isotretinoin  (ISO)
lipopolysaccharide  (ISO)
methimazole  (EXP)
N-nitrosodimethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
panobinostat  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pomalidomide  (ISO)
propanal  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:9391090   PMID:10631184   PMID:16314316   PMID:18184866   PMID:19011221   PMID:19375645  


Genomics

Comparative Map Data
Lmo2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83110,810,162 - 110,832,895 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3110,809,912 - 110,833,075 (+)EnsemblGRCr8
mRatBN7.2390,355,234 - 90,377,970 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl390,365,883 - 90,377,953 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx393,848,260 - 93,870,995 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03102,447,339 - 102,470,072 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03100,277,857 - 100,300,590 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0393,909,156 - 93,931,888 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl393,909,156 - 93,931,871 (+)Ensemblrn6Rnor6.0
Rnor_5.03100,549,307 - 100,572,039 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4389,356,199 - 89,367,641 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera389,416,677 - 89,439,412 (+)NCBICelera
RGSC_v3.1389,252,944 - 89,263,314 (+)NCBI
Cytogenetic Map3q32NCBI
LMO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381133,858,576 - 33,892,076 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1133,858,574 - 33,892,076 (-)Ensemblhg38GRCh38
GRCh371133,880,122 - 33,913,623 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361133,836,698 - 33,870,412 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341133,836,700 - 33,870,412NCBI
Celera1134,027,627 - 34,061,421 (-)NCBICelera
Cytogenetic Map11p13NCBI
HuRef1133,576,315 - 33,610,063 (-)NCBIHuRef
CHM1_11133,879,643 - 33,913,368 (-)NCBICHM1_1
T2T-CHM13v2.01133,995,616 - 34,029,225 (-)NCBIT2T-CHM13v2.0
Lmo2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392103,788,309 - 103,812,223 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2103,788,331 - 103,812,223 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382103,957,903 - 103,981,878 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2103,957,986 - 103,981,878 (+)Ensemblmm10GRCm38
MGSCv372103,798,152 - 103,822,035 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362103,771,062 - 103,782,713 (+)NCBIMGSCv36mm8
Celera2105,204,167 - 105,227,999 (+)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.46NCBI
Lmo2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542212,354,845 - 12,362,470 (+)Ensembl
ChiLan1.0NW_00495542212,354,865 - 12,362,026 (+)NCBIChiLan1.0ChiLan1.0
LMO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2936,077,833 - 36,110,953 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11136,082,565 - 36,115,729 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01133,830,370 - 33,863,960 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11133,712,099 - 33,720,729 (-)NCBIPanPan1.1PanPan1.1panPan2
LMO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha1833,481,882 - 33,492,473 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01834,487,785 - 34,497,780 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1834,486,702 - 34,497,791 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11834,045,610 - 34,056,746 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01833,639,096 - 33,649,686 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01834,274,467 - 34,285,055 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lmo2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494730,982,272 - 30,992,326 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365334,107,067 - 4,117,222 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365334,107,073 - 4,117,121 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LMO2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl227,044,763 - 27,055,453 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1227,033,924 - 27,055,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2229,401,270 - 29,422,801 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LMO2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1131,382,437 - 31,416,256 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl131,404,872 - 31,416,883 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666038128,481,321 - 128,514,918 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lmo2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476713,245,984 - 13,257,440 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476713,245,783 - 13,257,322 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Lmo2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1581,798,224 - 81,810,207 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Lmo2
138 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:87
Count of miRNA genes:64
Interacting mature miRNAs:82
Transcripts:ENSRNOT00000012625
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)351490129111359995Rat
1358293Bw38Body weight QTL 3860.0000031body mass (VT:0001259)body weight (CMO:0000012)374364268119364268Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)396509147141509147Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)393829559138829559Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3101255536134750886Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)396509147141509147Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)370311536115311536Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)381541464126563126Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)390755164141509147Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat

Markers in Region
AU048719  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2390,361,331 - 90,361,532 (+)MAPPERmRatBN7.2
Rnor_6.0393,915,254 - 93,915,454NCBIRnor6.0
Rnor_5.03100,555,405 - 100,555,605UniSTSRnor5.0
RGSC_v3.4389,351,006 - 89,351,206UniSTSRGSC3.4
Celera389,422,775 - 89,422,975UniSTS
Cytogenetic Map3q32UniSTS
PMC309712P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2390,372,362 - 90,372,546 (+)MAPPERmRatBN7.2
Rnor_6.0393,926,281 - 93,926,464NCBIRnor6.0
Rnor_5.03100,566,432 - 100,566,615UniSTSRnor5.0
RGSC_v3.4389,362,034 - 89,362,217UniSTSRGSC3.4
Celera389,433,805 - 89,433,988UniSTS
Cytogenetic Map3q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000012625   ⟹   ENSRNOP00000012625
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3110,821,569 - 110,833,075 (+)Ensembl
mRatBN7.2 Ensembl390,366,528 - 90,377,953 (+)Ensembl
Rnor_6.0 Ensembl393,920,447 - 93,931,871 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000083527   ⟹   ENSRNOP00000075577
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3110,809,912 - 110,833,075 (+)Ensembl
mRatBN7.2 Ensembl390,371,634 - 90,377,953 (+)Ensembl
Rnor_6.0 Ensembl393,920,013 - 93,931,871 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090365   ⟹   ENSRNOP00000072744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3110,820,833 - 110,833,075 (+)Ensembl
mRatBN7.2 Ensembl390,365,883 - 90,377,953 (+)Ensembl
Rnor_6.0 Ensembl393,909,156 - 93,931,871 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000169536   ⟹   ENSRNOP00000111779
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3110,821,578 - 110,833,075 (+)Ensembl
RefSeq Acc Id: NM_001037358   ⟹   NP_001032435
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83110,821,453 - 110,832,895 (+)NCBI
mRatBN7.2390,366,528 - 90,377,970 (+)NCBI
Rnor_6.0393,920,447 - 93,931,888 (+)NCBI
Rnor_5.03100,549,307 - 100,572,039 (+)NCBI
RGSC_v3.4389,356,199 - 89,367,641 (+)RGD
Celera389,427,970 - 89,439,412 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001244779   ⟹   NP_001231708
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83110,810,162 - 110,832,895 (+)NCBI
mRatBN7.2390,355,234 - 90,377,970 (+)NCBI
Rnor_6.0393,909,156 - 93,931,888 (+)NCBI
Rnor_5.03100,549,307 - 100,572,039 (+)NCBI
Celera389,416,677 - 89,439,412 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001244780   ⟹   NP_001231709
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83110,821,019 - 110,832,895 (+)NCBI
mRatBN7.2390,366,094 - 90,377,970 (+)NCBI
Rnor_6.0393,920,013 - 93,931,888 (+)NCBI
Rnor_5.03100,549,307 - 100,572,039 (+)NCBI
Celera389,427,536 - 89,439,412 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001244781   ⟹   NP_001231710
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83110,821,453 - 110,832,895 (+)NCBI
mRatBN7.2390,366,528 - 90,377,970 (+)NCBI
Rnor_6.0393,920,447 - 93,931,888 (+)NCBI
Rnor_5.03100,549,307 - 100,572,039 (+)NCBI
Celera389,427,970 - 89,439,412 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001032435   ⟸   NM_001037358
- Peptide Label: isoform 1
- UniProtKB: A0A0G2QC60 (UniProtKB/TrEMBL),   A0A0G2K3R4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001231708   ⟸   NM_001244779
- Peptide Label: isoform 2
- UniProtKB: Q3KRD2 (UniProtKB/TrEMBL),   F1LNA1 (UniProtKB/TrEMBL),   A0A0G2KAY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001231709   ⟸   NM_001244780
- Peptide Label: isoform 2
- UniProtKB: Q3KRD2 (UniProtKB/TrEMBL),   F1LNA1 (UniProtKB/TrEMBL),   A0A0G2KAY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001231710   ⟸   NM_001244781
- Peptide Label: isoform 2
- UniProtKB: Q3KRD2 (UniProtKB/TrEMBL),   F1LNA1 (UniProtKB/TrEMBL),   A0A0G2KAY6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012625   ⟸   ENSRNOT00000012625
Ensembl Acc Id: ENSRNOP00000072744   ⟸   ENSRNOT00000090365
Ensembl Acc Id: ENSRNOP00000075577   ⟸   ENSRNOT00000083527
Ensembl Acc Id: ENSRNOP00000111779   ⟸   ENSRNOT00000169536
Protein Domains
LIM zinc-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2QC60-F1-model_v2 AlphaFold A0A0G2QC60 1-220 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692256
Promoter ID:EPDNEW_R2781
Type:single initiation site
Name:Lmo2_1
Description:LIM domain only 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0393,920,539 - 93,920,599EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307101 AgrOrtholog
BioCyc Gene G2FUF-48551 BioCyc
Ensembl Genes ENSRNOG00000009401 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012625 ENTREZGENE
  ENSRNOT00000012625.8 UniProtKB/TrEMBL
  ENSRNOT00000083527.3 UniProtKB/TrEMBL
  ENSRNOT00000090365.3 UniProtKB/TrEMBL
  ENSRNOT00000169536.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine Rich Protein UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7930561 IMAGE-MGC_LOAD
InterPro LMO_RBTN_TF UniProtKB/TrEMBL
  Znf_LIM UniProtKB/TrEMBL
KEGG Report rno:362176 UniProtKB/TrEMBL
MGC_CLONE MGC:124678 IMAGE-MGC_LOAD
NCBI Gene 362176 ENTREZGENE
PANTHER LD11652P UniProtKB/TrEMBL
  RHOMBOTIN-2 UniProtKB/TrEMBL
Pfam LIM UniProtKB/TrEMBL
PhenoGen Lmo2 PhenoGen
PROSITE LIM_DOMAIN_1 UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009401 RatGTEx
SMART LIM UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
UniProt A0A0G2K3R4 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2KAY6 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2QC60 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0M849_RAT UniProtKB/TrEMBL
  F1LNA1 ENTREZGENE
  Q3KRD2 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1LNA1 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Lmo2  LIM domain only 2  Lmo2_predicted  LIM domain only 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Lmo2_predicted  LIM domain only 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED