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Gene: Pde6a (phosphodiesterase 6A) Rattus norvegicus

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Symbol:

Pde6a

Name:

phosphodiesterase 6A

RGD ID:

1306835

Description:

Predicted to enable 3',5'-cyclic-AMP phosphodiesterase activity and 3',5'-cyclic-GMP phosphodiesterase activity. Predicted to be involved in negative regulation of cAMP/PKA signal transduction and retina development in camera-type eye. Predicted to act upstream of or within photoreceptor cell maintenance. Predicted to be located in membrane. Predicted to be active in photoreceptor outer segment membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa 43. Orthologous to human PDE6A (phosphodiesterase 6A); PARTICIPATES IN altered visual phototransduction pathway; retinitis pigmentosa pathway; visual phototransduction pathway; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A; furan.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC307401; phosphodiesterase 6A, cGMP-specific, rod, alpha; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PDE6A (phosphodiesterase 6A)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Pde6a (phosphodiesterase 6A, cGMP-specific, rod, alpha)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pde6a (phosphodiesterase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PDE6A (phosphodiesterase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PDE6A (phosphodiesterase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pde6a (phosphodiesterase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PDE6A (phosphodiesterase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PDE6A (phosphodiesterase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pde6a (phosphodiesterase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Pde6a (phosphodiesterase 6A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PDE6B (phosphodiesterase 6B)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	PDE6A (phosphodiesterase 6A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PDE6A (phosphodiesterase 6A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pde6a (phosphodiesterase 6A, cGMP-specific, rod, alpha)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pde6a (phosphodiesterase 6A, cGMP-specific, rod, alpha)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PDE2	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	Pde6	Alliance	DIOPT (Ensembl Compara\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	pde6a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	56,947,249 - 57,019,015 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	56,947,249 - 57,019,015 (+)	Ensembl				GRCr8
mRatBN7.2	18	54,676,863 - 54,748,640 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	54,676,863 - 54,748,816 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	18	56,765,069 - 56,842,167 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	57,479,673 - 57,556,770 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	55,300,743 - 55,372,519 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	56,544,652 - 56,617,480 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	56,544,652 - 56,617,480 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	55,775,712 - 55,848,855 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	57,194,726 - 57,268,536 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	52,829,228 - 52,901,931 (+)	NCBI		Celera
RGSC_v3.1	18	57,267,060 - 57,339,325 (+)	NCBI
Cytogenetic Map	18	q12.1	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

fundus dystrophy (ISO)

genetic disease (ISO)

Leber congenital amaurosis (ISO)

retinitis pigmentosa (ISO,ISS)

retinitis pigmentosa 1 (ISO)

retinitis pigmentosa 43 (ISO)

Usher syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-sulfonyldiphenol (ISO)

acrylamide (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

copper(II) sulfate (ISO)

diquat (ISO)

furan (EXP)

isotretinoin (ISO)

methapyrilene (ISO)

methoxychlor (EXP)

monosodium L-glutamate (ISO)

nickel atom (ISO)

okadaic acid (ISO)

propanal (ISO)

sodium arsenite (ISO)

trichloroethene (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

negative regulation of cAMP/PKA signal transduction (IBA)

photoreceptor cell maintenance (ISO)

retina development in camera-type eye (IBA,IEA,ISO)

signal transduction (IEA)

visual perception (IEA)

Cellular Component

membrane (IEA)

photoreceptor outer segment membrane (IBA,ISS)

Molecular Function

3',5'-cyclic-AMP phosphodiesterase activity (IBA)

3',5'-cyclic-GMP phosphodiesterase activity (IBA,ISS)

3',5'-cyclic-nucleotide phosphodiesterase activity (IEA)

hydrolase activity (IEA)

metal ion binding (IEA)

phosphoric diester hydrolase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

altered visual phototransduction pathway (ISO)

purine metabolic pathway (IEA)

retinitis pigmentosa pathway (ISO)

visual phototransduction pathway (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Characteristics of photoreceptor PDE (PDE6): similarities and differences to PDE5.	Cote RH Int J Impot Res. 2004 Jun;16 Suppl 1:S28-33.
2.	Genes and mutations causing retinitis pigmentosa.	Daiger SP, etal., Clin Genet. 2013 Aug;84(2):132-41. doi: 10.1111/cge.12203. Epub 2013 Jun 19.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	Online Mendelian Inheritance in Man, OMIM (TM).	Online Mendelian Inheritance in Man, OMIM (TM).
7.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Comprehensive gene review and curation	RGD comprehensive gene curation
11.	Photoreceptor degeneration: genetic and mechanistic dissection of a complex trait.	Wright AF, etal., Nat Rev Genet. 2010 Apr;11(4):273-84. doi: 10.1038/nrg2717.

Additional References at PubMed

PMID:21052544	PMID:22183357

Genomics

Comparative Map Data

Pde6a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	56,947,249 - 57,019,015 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	56,947,249 - 57,019,015 (+)	Ensembl				GRCr8
mRatBN7.2	18	54,676,863 - 54,748,640 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	54,676,863 - 54,748,816 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	18	56,765,069 - 56,842,167 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	57,479,673 - 57,556,770 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	55,300,743 - 55,372,519 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	56,544,652 - 56,617,480 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	56,544,652 - 56,617,480 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	55,775,712 - 55,848,855 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	57,194,726 - 57,268,536 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	52,829,228 - 52,901,931 (+)	NCBI		Celera
RGSC_v3.1	18	57,267,060 - 57,339,325 (+)	NCBI
Cytogenetic Map	18	q12.1	NCBI

PDE6A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	149,857,953 - 149,944,793 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	149,857,953 - 149,945,287 (-)	Ensembl			hg38	GRCh38
GRCh37	5	149,237,516 - 149,324,356 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	149,220,410 - 149,304,549 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	5	149,220,419 - 149,304,549	NCBI
Celera	5	145,318,881 - 145,405,751 (-)	NCBI		Celera
Cytogenetic Map	5	q32	NCBI
HuRef	5	144,384,347 - 144,472,303 (-)	NCBI		HuRef
CHM1_1	5	148,670,177 - 148,757,019 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	150,394,428 - 150,481,347 (-)	NCBI		T2T-CHM13v2.0

Pde6a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	61,353,546 - 61,426,698 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	61,353,387 - 61,422,995 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	18	61,220,474 - 61,289,750 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	61,220,315 - 61,289,924 (+)	Ensembl			mm10	GRCm38
MGSCv37	18	61,380,153 - 61,449,404 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	18	61,345,868 - 61,415,119 (+)	NCBI		MGSCv36	mm8
Celera	18	62,507,018 - 62,573,593 (+)	NCBI		Celera
Cytogenetic Map	18	E1	NCBI
cM Map	18	34.41	NCBI

Pde6a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	4,566,271 - 4,637,070 (+)	Ensembl
ChiLan1.0	NW_004955415	4,556,636 - 4,637,070 (+)	NCBI	ChiLan1.0	ChiLan1.0

PDE6A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	145,086,567 - 145,173,739 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	143,226,116 - 143,313,288 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	145,283,505 - 145,369,596 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	151,289,225 - 151,375,952 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	151,294,041 - 151,375,832 (-)	Ensembl			panPan2	panpan1.1

PDE6A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	59,103,965 - 59,163,857 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	59,103,945 - 59,163,857 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	58,869,721 - 58,929,621 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	59,584,148 - 59,644,927 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	59,584,982 - 59,644,927 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	59,373,301 - 59,433,215 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	59,487,640 - 59,547,674 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	60,018,959 - 60,078,866 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pde6a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	143,444,055 - 143,514,360 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936504	5,018,064 - 5,092,024 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936504	5,018,171 - 5,088,333 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PDE6A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	150,927,770 - 150,985,318 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	150,926,652 - 150,986,050 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	157,742,261 - 157,800,838 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PDE6A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	52,465,497 - 52,550,671 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	52,468,022 - 52,549,599 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666034	25,167,432 - 25,252,764 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pde6a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624774	9,182,865 - 9,248,537 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624774	9,179,272 - 9,291,484 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pde6a
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	15	70,659,965 - 70,728,824 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pde6a
612 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	122
Count of miRNA genes:	95
Interacting mature miRNAs:	107
Transcripts:	ENSRNOT00000024171
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331733	Bp233	Blood pressure QTL 233	3.97196		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	25071126	83910656	Rat
1358358	Sradr6	Stress Responsive Adrenal Weight QTL 6	2.49		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	18	22015562	61600538	Rat
1331730	Scl27	Serum cholesterol level QTL 27	3.826		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	18	54490801	86134022	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	23494057	85487725	Rat
1331742	Bp228	Blood pressure QTL 228	3.88752		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31610505	77371277	Rat
1331736	Bp227	Blood pressure QTL 227	2.791		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	48917054	60064728	Rat
1300125	Rf26	Renal function QTL 26	3.2		urine potassium amount (VT:0010539)	urine potassium excretion rate (CMO:0000761)	18	53350521	68120379	Rat
631834	Sach3	Saccharin preference QTL 3	3.9	0.01	consumption behavior trait (VT:0002069)	calculated saccharin drink intake volume (CMO:0001600)	18	38575919	83575919	Rat
12904668	Bw188	Body weight QTL 188		0.03	body mass (VT:0001259)	body weight (CMO:0000012)	18	26822186	71822186	Rat
12904669	Cm125	Cardiac mass QTL 125		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	26822186	71822186	Rat
6893683	Bw110	Body weight QTL 110	2.7	0.002	body mass (VT:0001259)	body weight (CMO:0000012)	18	45620306	86134022	Rat
12904670	Cm126	Cardiac mass QTL 126		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	26822186	71822186	Rat
1331727	Bp237	Blood pressure QTL 237	3.053		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31610505	63968306	Rat
12904677	Kidm72	Kidney mass QTL 72		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	26822186	71822186	Rat
9589041	Epfw12	Epididymal fat weight QTL 12	17.08	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	18	48915737	86134022	Rat
8694432	Bw165	Body weight QTL 165	3.81	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	18	48915737	86134022	Rat
12904673	Cm127	Cardiac mass QTL 127		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	26822186	71822186	Rat
12904675	Am19	Aortic mass QTL 19		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	26822186	71822186	Rat
70185	BpQTLcluster15	Blood pressure QTL cluster 15	4.61		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	18	53845175	61982387	Rat
1331774	Bp226	Blood pressure QTL 226	4.41065		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31610505	77371277	Rat
9589816	Gluco68	Glucose level QTL 68	7.25	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	31990891	76990891	Rat
1331770	Bp234	Blood pressure QTL 234	3.807		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	45620306	86134022	Rat
61360	Eaey	Experimental allergic encephalomyelitis QTL y	3		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis duration (CMO:0001424)	18	49187226	62647720	Rat
2303120	Mamtr8	Mammary tumor resistance QTL 8		0.001	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	18	31610505	85493247	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	12066482	85493247	Rat
12880368	Bw187	Body weight QTL 187		0.045	body mass (VT:0001259)	body weight (CMO:0000012)	18	33379158	78379158	Rat
61367	Iddm4	Insulin dependent diabetes mellitus QTL 4	2.33	0.0074	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	40462383	85462383	Rat
1359020	Ppulsi2	Prepulse inhibition QTL 2	2.71		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	18	54490801	76272247	Rat
1331752	Bw27	Body weight QTL 27	2.963		body mass (VT:0001259)	body weight (CMO:0000012)	18	54490801	68120379	Rat
9590318	Scort22	Serum corticosterone level QTL 22	7.64	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	31990891	76990891	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	12066482	85493247	Rat
1331754	Bp230	Blood pressure QTL 230	4.61609		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	15642280	86134022	Rat
12904069	Cm123	Cardiac mass QTL 123		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	33379158	78379158	Rat
1331798	Bp224	Blood pressure QTL 224	3.53873		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31610505	77371277	Rat
12904070	Cm124	Cardiac mass QTL 124		0.01	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	33379158	78379158	Rat
2303584	Gluco55	Glucose level QTL 55	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	18	50795212	86134022	Rat
12904071	Am18	Aortic mass QTL 18		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	33379158	78379158	Rat
2301413	Bp318	Blood pressure QTL 318		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	26822186	71822186	Rat
61383	Bp47	Blood pressure QTL 47	17.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	31522783	76522783	Rat
12904067	Cm122	Cardiac mass QTL 122		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	33379158	78379158	Rat
1331806	Bp229	Blood pressure QTL 229	4.36484		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	48917054	60064728	Rat
2301417	Bp319	Blood pressure QTL 319		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	33379158	78379158	Rat
12904073	Kidm71	Kidney mass QTL 71		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	33379158	78379158	Rat
1331780	Bp238	Blood pressure QTL 238	3.269		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	48917054	60064728	Rat
1331776	Bp225	Blood pressure QTL 225	2.829		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	31610505	77371277	Rat
631518	Bw11	Body weight QTL 11	2.8		body mass (VT:0001259)	body weight (CMO:0000012)	18	36121626	81121626	Rat
1641923	Colcr8	Colorectal carcinoma resistance QTL 8	3.1	0.0014	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	18	31990891	76990891	Rat
8694366	Abfw8	Abdominal fat weight QTL 8	6.38	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	18	48915737	86134022	Rat
631509	Sald2	Serum aldosterone level QTL 2	2.9		blood aldosterone amount (VT:0005346)	serum aldosterone level (CMO:0000487)	18	26415821	71415821	Rat
631274	Sprol1	Serum protein level QTL 1	5.3		blood total protein amount (VT:0005567)	serum total protein level (CMO:0000661)	18	31644508	79484311	Rat
1598832	Glom11	Glomerulus QTL 11	2.9		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	53266671	86134022	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19553532	85493247	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	12066482	57066482	Rat
8694378	Bw157	Body weight QTL 157	3.59	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	18	31990891	76990891	Rat
2303571	Bw92	Body weight QTL 92	3		body mass (VT:0001259)	body weight (CMO:0000012)	18	50795212	86134022	Rat
61429	Cia17	Collagen induced arthritis QTL 17	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	18	31610505	72538878	Rat
7411719	Strs5	Sensitivity to stroke QTL 5	9.4		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	18	52198059	68120379	Rat

Markers in Region

RH135441

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	54,697,873 - 54,698,075 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	56,565,661 - 56,565,862	NCBI	Rnor6.0
Rnor_5.0	18	55,796,721 - 55,796,922	UniSTS	Rnor5.0
RGSC_v3.4	18	57,215,735 - 57,215,936	UniSTS	RGSC3.4
Celera	18	52,850,237 - 52,850,438	UniSTS
Cytogenetic Map	18	q12.1	UniSTS

RH139280

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	54,748,272 - 54,748,438 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	56,616,109 - 56,616,274	NCBI	Rnor6.0
Rnor_5.0	18	55,847,484 - 55,847,649	UniSTS	Rnor5.0
RGSC_v3.4	18	57,267,165 - 57,267,330	UniSTS	RGSC3.4
Celera	18	52,900,589 - 52,900,754	UniSTS
RH 3.4 Map	18	535.5	UniSTS
Cytogenetic Map	18	q12.1	UniSTS

RH139346

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	54,703,049 - 54,703,188 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	56,570,836 - 56,570,974	NCBI	Rnor6.0
Rnor_5.0	18	55,801,897 - 55,802,035	UniSTS	Rnor5.0
RGSC_v3.4	18	57,220,910 - 57,221,048	UniSTS	RGSC3.4
Celera	18	52,855,408 - 52,855,546	UniSTS
Cytogenetic Map	18	q12.1	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
13	9	25	65	41	45	17	52	17	6	160	95	7	46	27	70	28	13	13

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107386	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC122967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473971	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000024171 ⟹ ENSRNOP00000024171

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	56,947,249 - 57,019,015 (+)	Ensembl
mRatBN7.2 Ensembl	18	54,676,863 - 54,748,816 (+)	Ensembl
Rnor_6.0 Ensembl	18	56,544,652 - 56,617,480 (+)	Ensembl

RefSeq Acc Id:

NM_001107386 ⟹ NP_001100856

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	56,947,249 - 57,019,015 (+)	NCBI
mRatBN7.2	18	54,676,863 - 54,748,640 (+)	NCBI
Rnor_6.0	18	56,544,652 - 56,617,480 (+)	NCBI
Rnor_5.0	18	55,775,712 - 55,848,855 (+)	NCBI
RGSC_v3.4	18	57,194,726 - 57,268,536 (+)	RGD
Celera	18	52,829,228 - 52,901,931 (+)	RGD

Sequence:

show sequence

AAGGTCAGATTGAGGTGGGACATATTGAAATCCATTTGCTTGGAAACTGCCCTGGAAAGGCCGG
AGCCTGAGCCTCTCCTTGGGAGCAGCTAGAGGTCATCTTAGCCATGGGTGAGGTGACAGCAGAG
GAGGTAGAAAAGTTCCTGGATTCAAATATTGGCTTTGCCAAACAATACTATAATTTTCACTACC
GGGGGAAGGTCGTCTCAGACCTCCTCGGGGCCAAGGAGGCAGCCGTGGACTTCAGCAACTACCA
CGATGTGAACAGGGTGGAGGAGAGTGAGATCATCTTTGACCTCCTGCGGGACTTTCAGGAGAAC
TTACAGGCCGAGAAATGCACGTTCAATGTCATGAAGAAGCTCTGCTTCCTCCTGCGGGCTGACC
GCATGAGCCTGTTCATGTACAGGACCCGCAATGGCATTGCAGAGCTAGCCACCAGGCTCTTCAA
CGTCCACAAGGATGCCGTCCTAGAGGACTGCTTGGTGATGCCAGACTCCGAGATTGTCTTCCCT
TTGGACATGGGTGTCGTGGGCCACGTCGCACACTCCAAAAAGATCGCCAATGTCCCCAACACAG
AAGAGGATGAGCATTTCTGCGACTTCGTGGACAGCCTCACAGAATATCAGACCAAGAGCATCCT
GGCATCCCCCATCATGAATGGGAAGGACGTGGTAGCCATAATTATGGCTGTGAATAAAATAGAT
GAACCCCACTTCACCAAGAGAGATGAAGAGATTCTTCTCAAATACCTCAACTTTGTGAATCTGA
TCATGAAGGTATTCCACCTGAGTTACCTGCACAACTGTGAGACCCGGCGTGGCCAGATATTGCT
GTGGTCTGGAAGCAAGGTCTTCGAAGAGCTCACGGATATAGAGAGGCAGTTCCACAAGGCCCTG
TATACGGTCCGAGCTTTTCTCAACTGTGACAGATACTCTGTAGGACTCTTAGACATGACCAAAC
AGAAGGAATTTTTTGATGTGTGGCCAGTTCTGATGGGCGAGGCCCCAGCCTACTCTGGTCCCAG
GACTCCAGATGGAAGGGAAATTAACTTTTACAAGGTCATTGACTACATCCTGCATGGCAAAGAA
GACATCAAAGTAATCCCGAACCCACCTGCTGACCACTGGGCTCTAGTTAGCGGTCTTCCCACTT
ATGTGGCTCAAAATGGTCTGATCTGCAATATAATGAATGCGCCTGCAGAGGACTTTTTTGAATT
CCAGAAAGAGCCTCTGGATGAATCTGGATGGATGATTAAAAACGTACTCTCCATGCCGATTGTC
AACAAGAAGGAAGAGATCGTGGGCGTGGCCACATTTTACAATCGCAAAGATGGGAAGCCCTTCG
ACGACATGGACGAGACCCTTATGGAGTCTTTGACTCAGTTTCTGGGCTGGTCAGTCTTAAACCC
TGACACCTACGAGTCCATGAACAAACTTGAGAACAGGAAGGATATCTTCCAGGACATCGTAAAA
TATCACGTCAAGTGTGATAATGAGGAAATTCAGAAGATCTTGAAAACCAGAGAGGTGTATGGCA
AAGAGCCGTGGGAATGCGAGGAGGAGGAGCTGGCTGAGATCCTGCAAGAAGAACTTCCAGATGC
CGAGAAATATGAAATCAACAAGTTTCACTTCAGTGACCTGCCCCTTACGGAACTGGAGCTGGTG
AAATGCGGCATACAGATGTACTATGAGCTCAGAGTGGTGGACAAGTTCCACATCCCGCAAGAGG
CCCTGGTGCGCTTCATGTATTCGCTAAGCAAAGGCTACCGGAGGATCACTTACCACAATTGGCG
GCATGGCTTCAACGTGGGGCAGACCATGTTCTCCTTGCTGATGACAGGAAAGCTGAAGCGATAC
TTCACTGATTTGGAGGCCTTGGCCATGGTCACTGCAGCCTTCTGTCATGACATTGACCACAGAG
GCACGAACAACCTCTACCAGATGAAATCACAGAACCCCCTGGCCAAGCTTCATGGGTCCTCCAT
CCTGGAAAGGCATCATTTGGAGTTTGGCAAAACATTGCTGAGAGATGAGAGCCTGAATATCTTT
CAGAACCTGAATCGCCGGCAGCACGAGCATGCGATCCACATGATGGACATTGCGATCATCGCCA
CGGACCTTGCCCTGTATTTCAAGAAAAGGACAATGTTCCAGAAGATTGTGGATCAGTCAAAGAC
ATATGAGAGTACCCAGGAGTGGACCCAGTACATGATGCTGGAGCAGACACGGAAGGAAATTGTG
ATGGCCATGATGATGACCGCCTGTGACCTCTCAGCCATCACCAAGCCCTGGGAGGTGCAGAGCA
AGGTGGCTCTGCTGGTGGCTGCTGAATTCTGGGAGCAAGGTGACCTGGAGCGCACAGTGCTGCA
ACAGAATCCCATTCCCATGATGGACAGAAACAAGGCAGATGAACTCCCCAAGCTTCAGGTCGGC
TTCATTGATTTTGTGTGCACCTTTGTCTATAAGGAATTCTCCCGGTTTCATGAGGAGATCACAC
CCATGTTGGATGGGATCACTAACAACCGTAAGGAGTGGAAGGCGCTGGCTGATGAGTACGAGGC
CAGGATGAAAGCATTGGAGGAGGAGAAGCAGAAGCAGCAGGCAGCCAAGCAAGCTGCTTCCGGG
AACCAGCCAGGAGGGAACCCCAGTCCAGGGGGTGCACCTGCATCCAAGTCCTGTTGCATCCAGT
AGCTGAGCACACTGCCAGCAGGGGGCACGGCGCTCAGGAAGGAAGAGGTCACGAAGGCCACTAG
ACAGTTAAAGACTCAGGAGTTGAGAGGTGGCGGCAGACACAGCAGGCATCTATATCATCAAATG
GTCTTAGACGTTGTTTCTGCTTTGTTTTGTTTTGTTTTGCTTTGTTTTAGACAGCTCTGTCTGG
CCTGAAACTCTCTATGTAGCCGGTGTTGGCCTTGAACTCACAGACATCCACCTGCCTCTGTGTT
CTGAGTGCTGGGACCACACATGCACCCCCACATAGGTCTTAGAGATTGTTTTTAATCTTAAAAA
GTCCATTGAATTTAGCCCAATTTTCTATACCGACTTGATAATTTTTTTGTTCTTATGATGCTTG
TGATTCTTATAAGCTCTTTAAACTTAGTGTTTTATTATAAAAGTGTTTGCTAATCTCCAAAAGT
AGAGAATTATACATCAAATACCCACAAACTTACCCCAGATTTGAACATCAAACTCTGATCATGT
GTGCTTCTCGTGTCTTCATGTTCCTTTTCAATTTCTCTCCCTCTCCTCCTTTATCTCTCCCTCC
CTCCCTCCCTCCCTTCCTCTCTTCCTCCTTTCTAATTCCTACCATGTAGCCCTGGCTTGTTTTA
AACTCTCTCCATCCTCTGACCTCTGTGTTCACTACCACCCATGACTTGGCTGAAATATTTATGA
AAAGTTTCTGTACACATGGCTTCACTCCTCCACAGTCTTTGGAGGAGTTTATGCATCTTTACTG
GAATAAGCATCTTTAAAGGTCACACGCGGTAGCACGTGCCTGCAATCCCAGCCCTGGGGAAGGA
GAGAGGGGGAGGTCTTGAGTTTCAGAGACTTTGGTCTATACAGCAAGACCCCACTTCAAGGGGA
GGGTTACCCATCCTTAAAGGAGCAGAGTCTTTTCTAGCACAACACTGTCACAGGGAGGTAAAGG
CTTCGTACCCAGCCGTGCAGTGTATTCTGGTGAGCCCCAAATGGAGGCTGTGCAGTGTGTCTTG
GTGAACCCCAAATGGAGGACTTGGAGCTTCAGCAGACAGGTCCTTGGGGGTTTCCTTAGCTGAG
GGATACGCTGCATTTCTCAGAGGGATCTATGACTGAGGTGGACAAGTGTGATCACATTGCCCAA
CATGGGTAAACTGTGGAAGGCCAGTCTAGCTCCAGGCTGGAGTCTGTTTCCTAGGAAACCGAGC
TGTGACGCAAACTCTGAATCAACGACCGCAATGGTCCCAAAACTCTTTAAGAGACTAATTGTGC
TGAATGTGGTGGTGGAGACCTTTAATCCCAGGGTGCAGGAGGTGAAGGCAGGAGCATGTCAGTA
AATTCGAGGCCAGCTTGGTTTACACAGAAAGTTCCAGGCTGGTCTACAGTGTGAGACCTTGTTT
CAAACAAG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001100856	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM14597	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000024171
	ENSRNOP00000024171.4

RefSeq Acc Id:

NP_001100856 ⟸ NM_001107386

- UniProtKB:

D3Z8C9 (UniProtKB/TrEMBL), A6IXG6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGEVTAEEVEKFLDSNIGFAKQYYNFHYRGKVVSDLLGAKEAAVDFSNYHDVNRVEESEIIFDL
LRDFQENLQAEKCTFNVMKKLCFLLRADRMSLFMYRTRNGIAELATRLFNVHKDAVLEDCLVMP
DSEIVFPLDMGVVGHVAHSKKIANVPNTEEDEHFCDFVDSLTEYQTKSILASPIMNGKDVVAII
MAVNKIDEPHFTKRDEEILLKYLNFVNLIMKVFHLSYLHNCETRRGQILLWSGSKVFEELTDIE
RQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEAPAYSGPRTPDGREINFYKVID
YILHGKEDIKVIPNPPADHWALVSGLPTYVAQNGLICNIMNAPAEDFFEFQKEPLDESGWMIKN
VLSMPIVNKKEEIVGVATFYNRKDGKPFDDMDETLMESLTQFLGWSVLNPDTYESMNKLENRKD
IFQDIVKYHVKCDNEEIQKILKTREVYGKEPWECEEEELAEILQEELPDAEKYEINKFHFSDLP
LTELELVKCGIQMYYELRVVDKFHIPQEALVRFMYSLSKGYRRITYHNWRHGFNVGQTMFSLLM
TGKLKRYFTDLEALAMVTAAFCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLR
DESLNIFQNLNRRQHEHAIHMMDIAIIATDLALYFKKRTMFQKIVDQSKTYESTQEWTQYMMLE
QTRKEIVMAMMMTACDLSAITKPWEVQSKVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADE
LPKLQVGFIDFVCTFVYKEFSRFHEEITPMLDGITNNRKEWKALADEYEARMKALEEEKQKQQA
AKQAASGNQPGGNPSPGGAPASKSCCIQ

hide sequence

Ensembl Acc Id:

ENSRNOP00000024171 ⟸ ENSRNOT00000024171

Protein Domains

PDEase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3Z8C9-F1-model_v2	AlphaFold	D3Z8C9	1-860	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306835	AgrOrtholog
BioCyc Gene	G2FUF-7338	BioCyc
Ensembl Genes	ENSRNOG00000017816	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000024171	ENTREZGENE
	ENSRNOT00000024171.7	UniProtKB/TrEMBL
Gene3D-CATH	1.10.1300.10	UniProtKB/TrEMBL
	3.30.450.40	UniProtKB/TrEMBL
InterPro	GAF	UniProtKB/TrEMBL
	GAF_dom_like	UniProtKB/TrEMBL
	Metal-dep_PHydrolase_HD_dom	UniProtKB/TrEMBL
	PDEase	UniProtKB/TrEMBL
	PDEase	UniProtKB/TrEMBL
	PDEase_catalytic_dom_sf	UniProtKB/TrEMBL
	PDEase_CS	UniProtKB/TrEMBL
KEGG Report	rno:307401	UniProtKB/TrEMBL
NCBI Gene	307401	ENTREZGENE
PANTHER	CYCLIC NUCLEOTIDE PHOSPHODIESTERASE	UniProtKB/TrEMBL
Pfam	GAF	UniProtKB/TrEMBL
	PDEase_I	UniProtKB/TrEMBL
PhenoGen	Pde6a	PhenoGen
PRINTS	PDIESTERASE1	UniProtKB/TrEMBL
PROSITE	PDEASE_I	UniProtKB/TrEMBL
	PDEASE_I_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000017816	RatGTEx
SMART	GAF	UniProtKB/TrEMBL
	HDc	UniProtKB/TrEMBL
Superfamily-SCOP	GAF domain-like	UniProtKB/TrEMBL
	HD-domain/PDEase-like	UniProtKB/TrEMBL
UniProt	A6IXG6	ENTREZGENE, UniProtKB/TrEMBL
	D3Z8C9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-30	Pde6a	phosphodiesterase 6A	Pde6a	phosphodiesterase 6A, cGMP-specific, rod, alpha	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Pde6a	phosphodiesterase 6A, cGMP-specific, rod, alpha	Pde6a_predicted	phosphodiesterase 6A, cGMP-specific, rod, alpha (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Pde6a_predicted	phosphodiesterase 6A, cGMP-specific, rod, alpha (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)