Pltp (phospholipid transfer protein) - Rat Genome Database

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Gene: Pltp (phospholipid transfer protein) Rattus norvegicus
Analyze
Symbol: Pltp
Name: phospholipid transfer protein
RGD ID: 1306695
Description: Predicted to enable several functions, including lipid transfer activity; lipoprotein particle binding activity; and phospholipid binding activity. Predicted to be involved in several processes, including high-density lipoprotein particle remodeling; positive regulation of cholesterol efflux; and positive regulation of high-density lipoprotein particle assembly. Predicted to act upstream of or within flagellated sperm motility and vitamin E biosynthetic process. Predicted to be located in extracellular region and nucleus. Predicted to be part of high-density lipoprotein particle. Predicted to be active in extracellular space. Orthologous to human PLTP (phospholipid transfer protein); PARTICIPATES IN reverse cholesterol transport pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BPI fold containing family E; Bpife; LOC296371
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83173,994,162 - 174,011,982 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3173,994,162 - 174,012,505 (-)EnsemblGRCr8
mRatBN7.23153,574,825 - 153,592,647 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,574,825 - 153,592,647 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3157,383,266 - 157,401,093 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03165,882,236 - 165,900,067 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03163,626,011 - 163,643,842 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,304,469 - 161,322,289 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,304,469 - 161,322,289 (-)Ensemblrn6Rnor6.0
Rnor_5.03167,489,818 - 167,507,696 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43155,871,842 - 155,889,959 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3152,186,695 - 152,199,110 (-)NCBICelera
RGSC_v3.13155,777,877 - 155,796,306 (-)NCBI
Cytogenetic Map3q42NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R,R,R)-alpha-tocopherol  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bezafibrate  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (EXP)
bisphenol F  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
Cuprizon  (EXP)
cytarabine  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dimethylarsinic acid  (EXP)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenofibrate  (ISO)
fenthion  (ISO)
flutamide  (EXP)
fumonisin B1  (ISO)
gentamycin  (EXP)
GSK-J4  (ISO)
GW 3965  (ISO)
GW 501516  (ISO)
GW 7647  (ISO)
high-density lipoprotein cholesterol  (ISO)
indometacin  (ISO)
inulin  (ISO)
isotretinoin  (ISO)
Lasiocarpine  (EXP)
lipopolysaccharide  (ISO)
metformin  (EXP)
methidathion  (ISO)
methotrexate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monoethyl phthalate  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nickel sulfate  (ISO)
nimesulide  (EXP)
obeticholic acid  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
perfluorobutyric acid  (ISO)
perfluoroheptanoic acid  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
perfluoropentanoic acid  (ISO)
phenobarbital  (ISO)
phenytoin  (ISO)
phosgene  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
rotenone  (EXP)
sarin  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
thalidomide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP,ISO)
triphenyl phosphate  (EXP,ISO)
troglitazone  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Elevation of plasma phospholipid transfer protein increases the risk of atherosclerosis despite lower apolipoprotein B-containing lipoproteins. Lie J, etal., J Lipid Res. 2004 May;45(5):805-11. Epub 2004 Mar 1.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Cell-associated and extracellular phospholipid transfer protein in human coronary atherosclerosis. O'Brien KD, etal., Circulation. 2003 Jul 22;108(3):270-4. Epub 2003 Jun 30.
6. Reverse cholesterol transport and cholesterol efflux in atherosclerosis. Ohashi R, etal., QJM. 2005 Dec;98(12):845-56. Epub 2005 Oct 28.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Serum phospholipid transfer protein mass as a possible protective factor for coronary heart diseases. Yatsuya H, etal., Circ J. 2004 Jan;68(1):11-6.
Additional References at PubMed
PMID:7654777   PMID:9132017   PMID:11013307   PMID:16467369   PMID:16502470   PMID:19321130   PMID:21515415   PMID:24006456   PMID:24369175   PMID:27596005   PMID:29883800  


Genomics

Comparative Map Data
Pltp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83173,994,162 - 174,011,982 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3173,994,162 - 174,012,505 (-)EnsemblGRCr8
mRatBN7.23153,574,825 - 153,592,647 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,574,825 - 153,592,647 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3157,383,266 - 157,401,093 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03165,882,236 - 165,900,067 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03163,626,011 - 163,643,842 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,304,469 - 161,322,289 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,304,469 - 161,322,289 (-)Ensemblrn6Rnor6.0
Rnor_5.03167,489,818 - 167,507,696 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43155,871,842 - 155,889,959 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3152,186,695 - 152,199,110 (-)NCBICelera
RGSC_v3.13155,777,877 - 155,796,306 (-)NCBI
Cytogenetic Map3q42NCBI
PLTP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382045,898,620 - 45,912,155 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2045,898,621 - 45,912,235 (-)Ensemblhg38GRCh38
GRCh372044,527,259 - 44,540,794 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362043,960,804 - 43,974,193 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342043,960,803 - 43,974,193NCBI
Celera2041,238,859 - 41,252,245 (-)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2041,269,236 - 41,282,979 (-)NCBIHuRef
CHM1_12044,430,379 - 44,443,688 (-)NCBICHM1_1
T2T-CHM13v2.02047,635,115 - 47,648,212 (-)NCBIT2T-CHM13v2.0
Pltp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392164,681,441 - 164,699,564 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2164,681,438 - 164,699,631 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm382164,839,518 - 164,857,708 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2164,839,518 - 164,857,711 (-)Ensemblmm10GRCm38
MGSCv372164,665,018 - 164,683,208 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362164,530,723 - 164,548,913 (-)NCBIMGSCv36mm8
Celera2170,777,180 - 170,795,346 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.27NCBI
Pltp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544511,384,723 - 11,399,217 (+)Ensembl
ChiLan1.0NW_00495544511,384,723 - 11,399,217 (+)NCBIChiLan1.0ChiLan1.0
PLTP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22151,640,109 - 51,653,712 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12051,633,217 - 51,646,759 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02042,237,434 - 42,251,189 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12043,324,608 - 43,337,999 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2043,324,609 - 43,337,999 (-)EnsemblpanPan2panpan1.1
PLTP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,189,098 - 33,199,935 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,189,099 - 33,199,854 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2432,716,116 - 32,727,034 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02433,899,412 - 33,910,331 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2433,899,419 - 33,910,247 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12433,157,883 - 33,168,800 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02433,273,014 - 33,283,934 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02433,812,190 - 33,823,120 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pltp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,667,291 - 191,677,832 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365147,120,969 - 7,134,544 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365147,121,023 - 7,131,475 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLTP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1748,089,786 - 48,101,515 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11748,089,789 - 48,101,604 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21753,829,332 - 53,847,099 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLTP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1217,972,054 - 17,986,100 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl217,972,215 - 17,988,701 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605066,611,503 - 66,625,773 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pltp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247908,673,089 - 8,685,942 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247908,673,212 - 8,686,094 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Pltp
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15153,101,450 - 153,120,058 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:57
Count of miRNA genes:50
Interacting mature miRNAs:55
Transcripts:ENSRNOT00000022594
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3166376089177728348Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161492708189428310Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3166376089189428310Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161799493176036425Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3161799270187311134Rat
1582213Insul6Insulin level QTL 63.70.0009blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3166376089189428310Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1582256Insul9Insulin level QTL 94.40.0016blood insulin amount (VT:0001560)absolute change in serum insulin level (CMO:0002038)3155759447189428310Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
1582248Insul7Insulin level QTL 73.90.0041blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat

Markers in Region
AA891893  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83173,993,661 - 173,994,060 (+)Marker Load Pipeline
mRatBN7.23153,574,324 - 153,574,723 (+)MAPPERmRatBN7.2
Rnor_6.03161,303,969 - 161,304,367NCBIRnor6.0
Rnor_5.03167,489,318 - 167,489,716UniSTSRnor5.0
RGSC_v3.43155,871,342 - 155,871,740UniSTSRGSC3.4
Celera3152,181,930 - 152,182,328UniSTS
RH 3.4 Map31424.1UniSTS
Cytogenetic Map3q42UniSTS
AU048972  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23153,586,208 - 153,586,379 (+)MAPPERmRatBN7.2
Rnor_6.03161,315,851 - 161,316,021NCBIRnor6.0
Rnor_5.03167,500,947 - 167,501,117UniSTSRnor5.0
RGSC_v3.43155,883,521 - 155,883,691UniSTSRGSC3.4
Celera3152,192,680 - 152,192,842UniSTS
Cytogenetic Map3q42UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000022594   ⟹   ENSRNOP00000022594
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3173,994,162 - 174,012,505 (-)Ensembl
mRatBN7.2 Ensembl3153,574,825 - 153,592,647 (-)Ensembl
Rnor_6.0 Ensembl3161,304,469 - 161,322,289 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095240   ⟹   ENSRNOP00000091839
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3173,994,162 - 174,011,982 (-)Ensembl
mRatBN7.2 Ensembl3153,574,825 - 153,592,647 (-)Ensembl
RefSeq Acc Id: NM_001168543   ⟹   NP_001162015
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,994,162 - 174,011,982 (-)NCBI
mRatBN7.23153,574,825 - 153,592,647 (-)NCBI
Rnor_6.03161,304,469 - 161,322,289 (-)NCBI
Rnor_5.03167,489,818 - 167,507,696 (-)NCBI
RGSC_v3.43155,871,842 - 155,889,959 (-)RGD
Celera3152,186,695 - 152,199,110 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001162015 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAN61966 (Get FASTA)   NCBI Sequence Viewer  
  EDL96485 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022594.5
  ENSRNOP00000091839
  ENSRNOP00000091839.1
RefSeq Acc Id: NP_001162015   ⟸   NM_001168543
- Peptide Label: precursor
- UniProtKB: E9PSP1 (UniProtKB/TrEMBL),   A0A8I6AGE7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022594   ⟸   ENSRNOT00000022594
Ensembl Acc Id: ENSRNOP00000091839   ⟸   ENSRNOT00000095240
Protein Domains
Lipid-binding serum glycoprotein C-terminal   Lipid-binding serum glycoprotein N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PSP1-F1-model_v2 AlphaFold E9PSP1 1-496 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692670
Promoter ID:EPDNEW_R3194
Type:multiple initiation site
Name:Pltp_1
Description:phospholipid transfer protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03161,322,104 - 161,322,164EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306695 AgrOrtholog
BioCyc Gene G2FUF-46821 BioCyc
Ensembl Genes ENSRNOG00000016488 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000022594.8 UniProtKB/TrEMBL
  ENSRNOT00000095240 ENTREZGENE
  ENSRNOT00000095240.2 UniProtKB/TrEMBL
Gene3D-CATH Bactericidal permeability-increasing protein, domain 1 UniProtKB/TrEMBL
  Bactericidal permeability-increasing protein, domain 2 UniProtKB/TrEMBL
InterPro Bactericidal_perm-incr_a/b_dom UniProtKB/TrEMBL
  BPI/LBP UniProtKB/TrEMBL
  BPI/LBP/Plunc UniProtKB/TrEMBL
  Lipid-bd_serum_glycop_C UniProtKB/TrEMBL
  Lipid-bd_serum_glycop_CS UniProtKB/TrEMBL
  Lipid-bd_serum_glycop_N UniProtKB/TrEMBL
KEGG Report rno:296371 UniProtKB/TrEMBL
NCBI Gene 296371 ENTREZGENE
PANTHER PTHR10504 UniProtKB/TrEMBL
  PTHR10504:SF16 UniProtKB/TrEMBL
Pfam LBP_BPI_CETP UniProtKB/TrEMBL
  LBP_BPI_CETP_C UniProtKB/TrEMBL
PhenoGen Pltp PhenoGen
PIRSF Lipid_binding_protein UniProtKB/TrEMBL
PROSITE LBP_BPI_CETP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016488 RatGTEx
SMART BPI1 UniProtKB/TrEMBL
  BPI2 UniProtKB/TrEMBL
Superfamily-SCOP Bactericidal_perm-incr_a/b_dom UniProtKB/TrEMBL
UniProt A0A8I6AGE7 ENTREZGENE, UniProtKB/TrEMBL
  E9PSP1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Pltp  phospholipid transfer protein   Pltp_predicted  phospholipid transfer protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pltp_predicted  phospholipid transfer protein (predicted)      Symbol and Name status set to approved 70820 APPROVED