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Gene: Slc39a2 (solute carrier family 39 member 2) Rattus norvegicus

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Symbol:

Slc39a2

Name:

solute carrier family 39 member 2

RGD ID:

1306291

Description:

Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in cadmium ion transmembrane transport; keratinocyte differentiation; and zinc ion transmembrane transport. Predicted to act upstream of or within zinc ion transport. Predicted to be located in cytoplasmic vesicle. Predicted to be active in plasma membrane. Orthologous to human SLC39A2 (solute carrier family 39 member 2); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC305846; solute carrier family 39 (zinc transporter), member 2; zinc transporter ZIP2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC39A2 (solute carrier family 39 member 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Slc39a2 (solute carrier family 39 (zinc transporter), member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc39a2 (solute carrier family 39 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC39A2 (solute carrier family 39 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC39A2 (solute carrier family 39 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc39a2 (solute carrier family 39 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC39A2 (solute carrier family 39 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC39A2 (solute carrier family 39 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc39a2 (solute carrier family 39 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Slc39a2 (solute carrier family 39 member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	NHLH1 (nescient helix-loop-helix 1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	SLC39A2 (solute carrier family 39 member 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Slc39a2 (solute carrier family 39 (zinc transporter), member 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	slc39a1 (solute carrier family 39 member 1)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	slc39a1 (solute carrier family 39 member 1)	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ZRT1	Alliance	DIOPT (Ensembl Compara\|Hieranoid)
Saccharomyces cerevisiae (baker's yeast):	ZRT1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Zip42C.1	Alliance	DIOPT (InParanoid\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Zip42C.2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Zip42C.2	Alliance	DIOPT (InParanoid\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Zip89B	Alliance	DIOPT (Ensembl Compara\|InParanoid\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Zip89B	Alliance	DIOPT (InParanoid\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	zipt-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	zipt-1	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	zipt-2.3	Alliance	DIOPT (OMA\|OrthoInspector\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ZRT2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid)
Caenorhabditis elegans (roundworm):	zipt-2.1	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Caenorhabditis elegans (roundworm):	zipt-2.2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoInspector)
Caenorhabditis elegans (roundworm):	zipt-2.2	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	slc39a2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	slc39a2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	27,063,699 - 27,066,349 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	27,064,237 - 27,066,349 (+)	Ensembl				GRCr8
mRatBN7.2	15	24,590,738 - 24,592,850 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	24,590,738 - 24,592,850 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	27,361,775 - 27,363,891 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	28,317,522 - 28,319,634 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	26,570,466 - 26,572,578 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	28,295,044 - 28,297,688 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	28,295,368 - 28,297,684 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	32,108,556 - 32,110,668 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	27,328,308 - 27,330,420 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	24,896,195 - 24,898,307 (+)	NCBI		Celera
RGSC_v3.1	15	27,344,131 - 27,345,845 (+)	NCBI
Cytogenetic Map	15	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

17beta-estradiol 3-benzoate (EXP)

2-hydroxypropanoic acid (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

calcitriol (ISO)

carbamazepine (ISO)

CGP 52608 (ISO)

crocidolite asbestos (ISO)

cytarabine (ISO)

dimethylarsinic acid (ISO)

ethanol (ISO)

ethylparaben (ISO)

folic acid (ISO)

furan (EXP)

glutathione (ISO)

methylarsonic acid (ISO)

N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (ISO)

N-nitrosodiethylamine (ISO)

nitrofen (EXP)

ozone (ISO)

paracetamol (ISO)

phenobarbital (ISO)

rac-lactic acid (ISO)

rotenone (EXP)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sulforaphane (ISO)

testosterone (EXP)

triclosan (ISO)

valproic acid (ISO)

vitamin E (ISO)

zinc atom (EXP,ISO)

zinc dichloride (ISO)

zinc(0) (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cadmium ion transmembrane transport (ISO)

keratinocyte differentiation (IEA,ISO)

metal ion transport (IEA)

transmembrane transport (IEA)

zinc ion transmembrane transport (IBA,IEA,ISO)

zinc ion transport (ISO)

Cellular Component

cytoplasmic vesicle (ISO)

membrane (IEA)

plasma membrane (IBA,IEA,ISO)

Molecular Function

metal ion transmembrane transporter activity (IEA,ISO)

protein binding (ISO)

zinc ion transmembrane transporter activity (IBA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:14525987	PMID:14612438	PMID:18346199	PMID:20148757

Genomics

Comparative Map Data

Slc39a2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	27,063,699 - 27,066,349 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	27,064,237 - 27,066,349 (+)	Ensembl				GRCr8
mRatBN7.2	15	24,590,738 - 24,592,850 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	24,590,738 - 24,592,850 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	27,361,775 - 27,363,891 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	28,317,522 - 28,319,634 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	26,570,466 - 26,572,578 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	28,295,044 - 28,297,688 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	28,295,368 - 28,297,684 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	32,108,556 - 32,110,668 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	27,328,308 - 27,330,420 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	24,896,195 - 24,898,307 (+)	NCBI		Celera
RGSC_v3.1	15	27,344,131 - 27,345,845 (+)	NCBI
Cytogenetic Map	15	p14	NCBI

SLC39A2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	20,999,293 - 21,001,871 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	20,999,255 - 21,001,871 (+)	Ensembl			hg38	GRCh38
GRCh37	14	21,467,452 - 21,470,030 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	20,537,259 - 20,539,870 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	14	20,537,309 - 20,539,870	NCBI
Celera	14	1,328,279 - 1,330,899 (+)	NCBI		Celera
Cytogenetic Map	14	q11.2	NCBI
HuRef	14	1,588,520 - 1,591,140 (+)	NCBI		HuRef
CHM1_1	14	21,469,515 - 21,472,135 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	15,196,693 - 15,199,271 (+)	NCBI		T2T-CHM13v2.0

Slc39a2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	52,130,539 - 52,134,202 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	52,130,346 - 52,134,202 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	14	51,893,082 - 51,896,745 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	51,892,889 - 51,896,745 (+)	Ensembl			mm10	GRCm38
MGSCv37	14	52,513,285 - 52,516,420 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	14	50,815,559 - 50,818,696 (+)	NCBI		MGSCv36	mm8
Celera	14	48,878,496 - 48,881,630 (+)	NCBI		Celera
Cytogenetic Map	14	C2	NCBI
cM Map	14	26.71	NCBI

Slc39a2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955550	1,762,907 - 1,765,254 (+)	Ensembl
ChiLan1.0	NW_004955550	1,762,905 - 1,765,254 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC39A2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	22,449,102 - 22,455,203 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	21,667,086 - 21,671,597 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	1,813,992 - 1,818,226 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	19,896,112 - 19,898,728 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	19,896,112 - 19,898,728 (+)	Ensembl			panPan2	panpan1.1

SLC39A2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	18,099,310 - 18,102,884 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	18,100,785 - 18,102,896 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	18,584,806 - 18,588,423 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	18,360,111 - 18,363,728 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	18,361,630 - 18,363,726 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	18,041,468 - 18,045,085 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	18,097,460 - 18,101,077 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	18,225,334 - 18,228,951 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Slc39a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	32,298,786 - 32,302,504 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936880	209,738 - 211,531 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936880	207,810 - 211,876 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC39A2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	78,129,237 - 78,131,819 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	78,127,628 - 78,132,900 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SLC39A2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	29	21,472,627 - 21,475,549 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	29	21,473,123 - 21,475,252 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666059	24,960,605 - 24,963,604 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc39a2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624825	6,999,039 - 7,002,141 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624825	6,996,864 - 7,011,917 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Slc39a2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	12	72,001,212 - 72,003,326 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Slc39a2
10 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	226
Count of miRNA genes:	157
Interacting mature miRNAs:	176
Transcripts:	ENSRNOT00000013786
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1641913	Colcr2	Colorectal carcinoma resistance QTL 2	6.57	0.0197	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	15	2315759	47315759	Rat
5684946	Bss98	Bone structure and strength QTL 98	3.9	0.0026	tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	15	1	39411584	Rat
1641887	Alcrsp14	Alcohol response QTL 14			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	15	1	44836456	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2315759	53331089	Rat
10755503	Bp391	Blood pressure QTL 391	2.37		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	15	22728353	42072050	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	25285835	104695021	Rat
2324620	Coatc3	Coat color QTL 3			coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	15	22336351	52597086	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	25285835	104695021	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	19155762	87086765	Rat
10401805	Kidm51	Kidney mass QTL 51			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	15	2785923	47785923	Rat
1354657	Despr13	Despair related QTL 13		0.0022	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	15	1	32342855	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	14926594	71614418	Rat
631550	Bw7	Body weight QTL 7	3.6		body mass (VT:0001259)	body weight (CMO:0000012)	15	22336351	67336351	Rat
5685002	Bss103	Bone structure and strength QTL 103	2.8		tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	15	16911521	32439851	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	25285835	104695021	Rat

Markers in Region

RH138780

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	15	27,065,655 - 27,066,130 (+)	Marker Load Pipeline
mRatBN7.2	15	24,592,156 - 24,592,631 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	28,296,995 - 28,297,469	NCBI	Rnor6.0
Rnor_5.0	15	32,109,975 - 32,110,449	UniSTS	Rnor5.0
RGSC_v3.4	15	27,329,727 - 27,330,201	UniSTS	RGSC3.4
Celera	15	24,897,614 - 24,898,088	UniSTS
Cytogenetic Map	15	p14	UniSTS

UniSTS:547105

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	15	27,065,887 - 27,066,818 (+)	Marker Load Pipeline
mRatBN7.2	15	24,592,388 - 24,593,318 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	28,297,227 - 28,298,156	NCBI	Rnor6.0
Rnor_5.0	15	32,110,207 - 32,111,136	UniSTS	Rnor5.0
Celera	15	24,897,846 - 24,898,775	UniSTS
Cytogenetic Map	15	p14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
12	8	64	131	30	38	11	17	11	6	184	99	11	111	56	73	27	11	11

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107260	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770521	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC094516	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474040	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000013786 ⟹ ENSRNOP00000013786

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	27,064,237 - 27,066,349 (+)	Ensembl
mRatBN7.2 Ensembl	15	24,590,738 - 24,592,850 (+)	Ensembl
Rnor_6.0 Ensembl	15	28,295,368 - 28,297,684 (+)	Ensembl

RefSeq Acc Id:

NM_001107260 ⟹ NP_001100730

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	27,064,237 - 27,066,349 (+)	NCBI
mRatBN7.2	15	24,590,738 - 24,592,850 (+)	NCBI
Rnor_6.0	15	28,295,576 - 28,297,688 (+)	NCBI
Rnor_5.0	15	32,108,556 - 32,110,668 (+)	NCBI
RGSC_v3.4	15	27,328,308 - 27,330,420 (+)	RGD
Celera	15	24,896,195 - 24,898,307 (+)	RGD

Sequence:

show sequence

GCAGGGACAAGAGGGTTAGCAACAGTCCTGAAATTCACGCAAGGGAATACTCCACTTTGGCTGC
TTCAACCGTTCCTCGCTGCTTTCGCCTTTCTGAGGTCTCTGCTTACCCTACACCCCAGAGATGG
AGGTGCTACCAGGAGTTAAAATTGGCTGTGTGCTTGCCCTCCTGGTTTTCACACTGGGCTGTGG
TCTTACTCCCATCTACGTCAAATGGTTCCAGACGGATGCAGCAACAGGTCACCACCACAGGGTT
CTCAGCCTCCTGGGCTGCACCTCTGCCGGTGTCTTCCTGGGAGCAGGGTTGATGCATATGACTG
CTGAAGCCCTGGAGGGAATTGAGTCAGAAATTCAGAAATTCGTGGTGCAGAATAGTACAGGAAG
TAAGGGGAATTCTTCTCGTGATGCTGCTGCCAGTTACGTGGAGTACCCCTACGGAGAACTTGTC
ATCTCCCTGGGCTTTTTCTTTGTCTTCCTTTTGGAGTCGCTGGCCTTGCAGTGCTGTCACGGTG
CTGCTGGAGGATCGACAGTACAGGAGGAGGAATGGGGAGGGACTCATGCCTTCGGATTCCACAA
GCATCCACCCATACCCTCACCCTCACGGGGTCCCCTCCGCGCCCTCATCCTTCTGCTCTCGCTG
TCCTTTCATTCCGTATTCGAAGGTCTAGCTGTGGGACTGCAGGCAACCGTGGCAGCTACTGTAC
AGCTCTGCGTTGCTGTGCTGGCTCATAAGGGGCTTGTGGTGTTCAGCGTGGGCCTGAGGCTGGT
GAAGATCGGCACTGGACCACGATGGGCCACGTTCTGCATACTGTCCTTAGCTCTCATGTCTCCT
GTGGGCCTAGCCCTAGGGCTGACCGTGGCTGGTGGAGCCTCAGGACAAGCACAGGAATTAGCCC
AGGCGATATTAGAGGGCATAGCAGCTGGCACGTTTTTATATGTCACCTTCCTAGAAATTTTGCC
CCGGGAGCTGGCTTGTCCTGAGGCCCCTCTGGCCAAGTATGGCTGTGTGGCTGCCGGGTTTGCC
TTCATGGCCCTTATTGCTTTGTGGGCCTGATACATTCCTCACTGCCCTGTTAGACCTAGGATAA
CTTCTCCTGAGGACACTCCCTCAATAACTTAAGTCCTCAGACATTATTTTCAGTGAGACTAAAC
ATTTACTAGGTACAGACTAACCCAGATTTTATATACGTGAGATCCCGTCCTTGCTTGGGACTTA
GAAAGAATGTTTTGGTTACATGCCTATTTAACTGGAAAATTGGTATCAAGACCATCACTCCAGA
TTTGTTATTGTGTGTAATAAAATTCCCATTTTACCCGTTGTTCCCTTCA

hide sequence

RefSeq Acc Id:

XM_063274222 ⟹ XP_063130292

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	27,063,699 - 27,065,529 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100730	(Get FASTA)	NCBI Sequence Viewer
	XP_063130292	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL88446	(Get FASTA)	NCBI Sequence Viewer
	EDL88447	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000013786
	ENSRNOP00000013786.5

RefSeq Acc Id:

NP_001100730 ⟸ NM_001107260

- UniProtKB:

D3ZIN1 (UniProtKB/TrEMBL), A6KEE1 (UniProtKB/TrEMBL), A6KEE2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEVLPGVKIGCVLALLVFTLGCGLTPIYVKWFQTDAATGHHHRVLSLLGCTSAGVFLGAGLMHM
TAEALEGIESEIQKFVVQNSTGSKGNSSRDAAASYVEYPYGELVISLGFFFVFLLESLALQCCH
GAAGGSTVQEEEWGGTHAFGFHKHPPIPSPSRGPLRALILLLSLSFHSVFEGLAVGLQATVAAT
VQLCVAVLAHKGLVVFSVGLRLVKIGTGPRWATFCILSLALMSPVGLALGLTVAGGASGQAQEL
AQAILEGIAAGTFLYVTFLEILPRELACPEAPLAKYGCVAAGFAFMALIALWA

hide sequence

Ensembl Acc Id:

ENSRNOP00000013786 ⟸ ENSRNOT00000013786

RefSeq Acc Id:	XP_063130292 ⟸ XM_063274222
- Peptide Label:	isoform X1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZIN1-F1-model_v2	AlphaFold	D3ZIN1	1-309	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699631

Promoter ID:

EPDNEW_R10155

Type:

single initiation site

Name:

Slc39a2_1

Description:

solute carrier family 39 member 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	15	28,295,426 - 28,295,486	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306291	AgrOrtholog
BioCyc Gene	G2FUF-14003	BioCyc
Ensembl Genes	ENSRNOG00000010375	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000013786	ENTREZGENE
	ENSRNOT00000013786.8	UniProtKB/TrEMBL
InterPro	ZIP	UniProtKB/TrEMBL
KEGG Report	rno:305846	UniProtKB/TrEMBL
NCBI Gene	305846	ENTREZGENE
PANTHER	ZINC TRANSPORTER ZIP2	UniProtKB/TrEMBL
	ZINC/IRON TRANSPORTER	UniProtKB/TrEMBL
Pfam	Zip	UniProtKB/TrEMBL
PhenoGen	Slc39a2	PhenoGen
RatGTEx	ENSRNOG00000010375	RatGTEx
UniProt	A6KEE1	ENTREZGENE, UniProtKB/TrEMBL
	A6KEE2	ENTREZGENE, UniProtKB/TrEMBL
	D3ZIN1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-24	Slc39a2	solute carrier family 39 member 2	Slc39a2	solute carrier family 39 (zinc transporter), member 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Slc39a2	solute carrier family 39 (zinc transporter), member 2	Slc39a2_predicted	solute carrier family 39 (zinc transporter), member 2 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Slc39a2_predicted	solute carrier family 39 (zinc transporter), member 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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