Gene: Metrn (meteorin, glial cell differentiation regulator) Rattus norvegicus
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Symbol:
Metrn
Name:
meteorin, glial cell differentiation regulator
RGD ID:
1306222
Description:
Predicted to enable hormone activity. Predicted to be involved in glial cell differentiation and positive regulation of axonogenesis. Predicted to act upstream of or within radial glial cell differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human METRN (meteorin, glial cell differentiation regulator); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
hypoxia/reoxygenation regulatory factor; hyrac; LOC287151; meteorin; RGD1306222; similar to 1810034B16Rik protein
RGD Orthologs
Alliance Orthologs
More Info
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More Info
Species
Gene symbol and name
Data Source
Assertion derived from
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Orthologs 1
Homo sapiens (human):
METRN (meteorin, glial cell differentiation regulator)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Metrn (meteorin, glial cell differentiation regulator)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Metrn (meteorin, glial cell differentiation regulator)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
METRN (meteorin, glial cell differentiation regulator)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
METRN (meteorin, glial cell differentiation regulator)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Metrn (meteorin, glial cell differentiation regulator)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
METRN (meteorin, glial cell differentiation regulator)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
METRN (meteorin, glial cell differentiation regulator)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Metrn (meteorin, glial cell differentiation regulator)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Metrn (meteorin, glial cell differentiation regulator)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
METRN (meteorin, glial cell differentiation regulator)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Metrn (meteorin, glial cell differentiation regulator)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
metrn (meteorin, glial cell differentiation regulator)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 10 15,321,200 - 15,323,218 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 10 15,321,200 - 15,323,642 (-) Ensembl GRCr8 mRatBN7.2 10 14,816,684 - 14,818,702 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 10 14,816,572 - 14,818,701 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 10 19,555,693 - 19,557,711 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 10 19,044,570 - 19,046,588 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 10 14,544,689 - 14,546,707 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 10 15,164,439 - 15,166,457 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 10 15,164,439 - 15,166,457 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 10 14,977,382 - 14,979,400 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 10 15,062,082 - 15,064,100 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 10 14,485,660 - 14,487,678 (-) NCBI Celera RGSC_v3.1 10 15,062,081 - 15,064,100 (-) NCBI Cytogenetic Map 10 q12 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Metrn Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Metrn (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Metrn Rat 1,2-dimethylhydrazine increases expression ISO Metrn (Mus musculus) 6480464 1,2-Dimethylhydrazine results in increased expression of METRN mRNA CTD PMID:22206623 Metrn Rat 1,2-dimethylhydrazine multiple interactions ISO Metrn (Mus musculus) 6480464 Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of METRN mRNA] CTD PMID:22206623 Metrn Rat 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of METRN mRNA CTD PMID:32145629 Metrn Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Metrn (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Metrn Rat 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of METRN mRNA CTD PMID:21394737 Metrn Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Metrn (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Metrn Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Metrn (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of METRN mRNA CTD PMID:21570461|PMID:24680724 Metrn Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of METRN mRNA CTD PMID:33387578 Metrn Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of METRN mRNA CTD PMID:32109520 Metrn Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Metrn (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Metrn Rat 4,4'-sulfonyldiphenol multiple interactions ISO Metrn (Mus musculus) 6480464 [bisphenol S co-treated with Tretinoin] results in decreased expression of METRN mRNA CTD PMID:30951980 Metrn Rat 4,4'-sulfonyldiphenol increases expression ISO Metrn (Mus musculus) 6480464 bisphenol S results in increased expression of METRN mRNA CTD PMID:30951980 Metrn Rat 4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid decreases expression ISO METRN (Homo sapiens) 6480464 Am 580 results in decreased expression of METRN mRNA CTD PMID:16982809 Metrn Rat 4-hydroxyphenyl retinamide decreases expression ISO Metrn (Mus musculus) 6480464 Fenretinide results in decreased expression of METRN mRNA CTD PMID:28973697 Metrn Rat 5-fluorouracil multiple interactions ISO METRN (Homo sapiens) 6480464 METRN mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with more ... CTD PMID:16896004 Metrn Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of METRN mRNA CTD PMID:24780913 Metrn Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of METRN mRNA CTD PMID:31881176 Metrn Rat acrylamide decreases expression ISO METRN (Homo sapiens) 6480464 Acrylamide results in decreased expression of METRN mRNA CTD PMID:32763439 Metrn Rat all-trans-retinoic acid increases expression ISO METRN (Homo sapiens) 6480464 Tretinoin results in increased expression of METRN mRNA CTD PMID:23724009 Metrn Rat all-trans-retinoic acid multiple interactions ISO Metrn (Mus musculus) 6480464 [bisphenol S co-treated with Tretinoin] results in decreased expression of METRN mRNA CTD PMID:30951980 Metrn Rat antimycin A decreases expression ISO METRN (Homo sapiens) 6480464 Antimycin A results in decreased expression of METRN mRNA CTD PMID:33512557 Metrn Rat Aroclor 1254 increases expression ISO Metrn (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of METRN mRNA CTD PMID:23650126 Metrn Rat benzo[a]pyrene decreases expression ISO Metrn (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of METRN mRNA CTD PMID:22228805 Metrn Rat benzo[a]pyrene affects methylation ISO METRN (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of METRN promoter CTD PMID:27901495 Metrn Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of METRN mRNA CTD PMID:25181051|PMID:34947998 Metrn Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of METRN mRNA CTD PMID:32145629 Metrn Rat bisphenol A increases expression ISO Metrn (Mus musculus) 6480464 bisphenol A results in increased expression of METRN mRNA CTD PMID:30951980|PMID:33221593 Metrn Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of METRN gene CTD PMID:28505145 Metrn Rat bleomycin A5 increases expression ISO METRN (Homo sapiens) 6480464 bleomycetin results in increased expression of METRN mRNA CTD PMID:21040473 Metrn Rat cadmium atom multiple interactions ISO METRN (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of METRN more ... CTD PMID:35301059 Metrn Rat cadmium dichloride decreases expression ISO Metrn (Mus musculus) 6480464 Cadmium Chloride results in decreased expression of METRN mRNA CTD PMID:18974090 Metrn Rat cadmium dichloride multiple interactions ISO METRN (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of METRN more ... CTD PMID:35301059 Metrn Rat cadmium dichloride decreases methylation EXP 6480464 Cadmium Chloride results in decreased methylation of METRN promoter CTD PMID:22457795 Metrn Rat carbon nanotube increases expression ISO Metrn (Mus musculus) 6480464 Nanotubes, Carbon analog results in increased expression of METRN mRNA CTD PMID:25554681 Metrn Rat cisplatin decreases expression ISO METRN (Homo sapiens) 6480464 Cisplatin results in decreased expression of METRN mRNA CTD PMID:27392435 Metrn Rat clobetasol increases expression ISO Metrn (Mus musculus) 6480464 Clobetasol results in increased expression of METRN mRNA CTD PMID:27462272 Metrn Rat copper(II) sulfate decreases expression ISO METRN (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of METRN mRNA CTD PMID:19549813 Metrn Rat Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of METRN mRNA CTD PMID:27523638 Metrn Rat cyclophosphamide multiple interactions ISO METRN (Homo sapiens) 6480464 METRN mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with more ... CTD PMID:16896004 Metrn Rat cyclosporin A decreases expression ISO METRN (Homo sapiens) 6480464 Cyclosporine results in decreased expression of METRN mRNA CTD PMID:20106945 Metrn Rat cyclosporin A increases expression ISO Metrn (Mus musculus) 6480464 Cyclosporine results in increased expression of METRN mRNA CTD PMID:19770486 Metrn Rat deguelin decreases expression ISO METRN (Homo sapiens) 6480464 deguelin results in decreased expression of METRN mRNA CTD PMID:33512557 Metrn Rat Dibutyl phosphate affects expression ISO METRN (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of METRN mRNA CTD PMID:37042841 Metrn Rat dicrotophos decreases expression ISO METRN (Homo sapiens) 6480464 dicrotophos results in decreased expression of METRN mRNA CTD PMID:28302478 Metrn Rat dimethylselenide multiple interactions ISO METRN (Homo sapiens) 6480464 [[Reactive Oxygen Species results in increased oxidation of dimethylselenide] which results in increased expression of more ... CTD PMID:33656867 Metrn Rat dorsomorphin multiple interactions ISO METRN (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... CTD PMID:27188386 Metrn Rat doxorubicin multiple interactions ISO METRN (Homo sapiens) 6480464 METRN mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with more ... CTD PMID:16896004 Metrn Rat doxorubicin decreases expression ISO Metrn (Mus musculus) 6480464 Doxorubicin results in decreased expression of METRN mRNA CTD PMID:39631538 Metrn Rat endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of METRN mRNA CTD PMID:29391264 Metrn Rat entinostat multiple interactions ISO METRN (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... CTD PMID:27188386 Metrn Rat entinostat decreases expression ISO METRN (Homo sapiens) 6480464 entinostat results in decreased expression of METRN mRNA CTD PMID:26272509 Metrn Rat ethanol increases expression ISO Metrn (Mus musculus) 6480464 Ethanol results in increased expression of METRN mRNA CTD PMID:19167417|PMID:30319688 Metrn Rat exemestane increases expression ISO METRN (Homo sapiens) 6480464 exemestane results in increased expression of METRN mRNA CTD PMID:17254854 Metrn Rat folic acid decreases expression ISO Metrn (Mus musculus) 6480464 Folic Acid results in decreased expression of METRN mRNA CTD PMID:25629700 Metrn Rat folic acid multiple interactions ISO Metrn (Mus musculus) 6480464 Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of METRN mRNA] CTD PMID:22206623 Metrn Rat formaldehyde decreases expression ISO METRN (Homo sapiens) 6480464 Formaldehyde results in decreased expression of METRN mRNA CTD PMID:23649840 Metrn Rat isoprenaline decreases expression ISO Metrn (Mus musculus) 6480464 Isoproterenol results in decreased expression of METRN mRNA CTD PMID:20003209 Metrn Rat methyl methanesulfonate decreases expression ISO METRN (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of METRN mRNA CTD PMID:23649840 Metrn Rat oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of METRN mRNA CTD PMID:25729387 Metrn Rat paclitaxel multiple interactions ISO METRN (Homo sapiens) 6480464 METRN mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with more ... CTD PMID:16896004 Metrn Rat paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of METRN mRNA CTD PMID:33387578 Metrn Rat PCB138 multiple interactions ISO Metrn (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Metrn Rat reactive oxygen species multiple interactions ISO METRN (Homo sapiens) 6480464 [[Reactive Oxygen Species results in increased oxidation of dimethylselenide] which results in increased expression of more ... CTD PMID:33656867 Metrn Rat rotenone decreases expression ISO METRN (Homo sapiens) 6480464 Rotenone results in decreased expression of METRN protein CTD PMID:39603559 Metrn Rat SB 431542 multiple interactions ISO METRN (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... CTD PMID:27188386 Metrn Rat sodium arsenite decreases expression ISO METRN (Homo sapiens) 6480464 sodium arsenite results in decreased expression of METRN mRNA CTD PMID:38568856 Metrn Rat sodium arsenite increases expression ISO METRN (Homo sapiens) 6480464 sodium arsenite results in increased expression of METRN mRNA CTD PMID:34032870 Metrn Rat sunitinib decreases expression ISO METRN (Homo sapiens) 6480464 Sunitinib results in decreased expression of METRN mRNA CTD PMID:31533062 Metrn Rat tebufenpyrad decreases expression ISO METRN (Homo sapiens) 6480464 4-chloro-N-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of METRN mRNA CTD PMID:33512557 Metrn Rat tetrachloroethene decreases expression ISO Metrn (Mus musculus) 6480464 Tetrachloroethylene results in decreased expression of METRN mRNA CTD PMID:28973375 Metrn Rat thifluzamide decreases expression ISO METRN (Homo sapiens) 6480464 thifluzamide results in decreased expression of METRN mRNA CTD PMID:33512557 Metrn Rat thiram decreases expression ISO METRN (Homo sapiens) 6480464 Thiram results in decreased expression of METRN mRNA CTD PMID:38568856 Metrn Rat titanium dioxide decreases methylation ISO Metrn (Mus musculus) 6480464 titanium dioxide results in decreased methylation of METRN gene CTD PMID:35295148 Metrn Rat titanium dioxide increases methylation ISO Metrn (Mus musculus) 6480464 titanium dioxide results in increased methylation of METRN promoter CTD PMID:35295148 Metrn Rat topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of METRN mRNA CTD PMID:25729387 Metrn Rat topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of METRN mRNA CTD PMID:25729387 Metrn Rat trimellitic anhydride increases expression ISO Metrn (Mus musculus) 6480464 trimellitic anhydride results in increased expression of METRN mRNA CTD PMID:19042947 Metrn Rat tungsten increases expression ISO Metrn (Mus musculus) 6480464 Tungsten results in increased expression of METRN mRNA CTD PMID:30912803 Metrn Rat valproic acid increases methylation ISO METRN (Homo sapiens) 6480464 Valproic Acid results in increased methylation of METRN gene CTD PMID:29154799 Metrn Rat valproic acid increases expression ISO METRN (Homo sapiens) 6480464 Valproic Acid results in increased expression of METRN mRNA CTD PMID:19101580|PMID:23179753|PMID:29154799 Metrn Rat valproic acid affects expression ISO METRN (Homo sapiens) 6480464 Valproic Acid affects the expression of METRN mRNA CTD PMID:25979313|PMID:26072468 Metrn Rat valproic acid affects expression ISO Metrn (Mus musculus) 6480464 Valproic Acid affects the expression of METRN mRNA CTD PMID:26072468