Lrch4 (leucine rich repeats and calponin homology domain containing 4) - Rat Genome Database

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Gene: Lrch4 (leucine rich repeats and calponin homology domain containing 4) Rattus norvegicus
Analyze
Symbol: Lrch4
Name: leucine rich repeats and calponin homology domain containing 4
RGD ID: 1306145
Description: Predicted to be involved in membrane raft assembly and positive regulation of toll-like receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be active in PML body. Orthologous to human LRCH4 (leucine rich repeats and calponin homology domain containing 4); INTERACTS WITH bisphenol A; Cuprizon; paracetamol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: leucine-rich repeat and calponin homology domain-containing protein 4; leucine-rich repeats and calponin homology (CH) domain containing 4; LOC360779
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81224,694,364 - 24,709,354 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1224,694,370 - 24,706,412 (-)EnsemblGRCr8
mRatBN7.21219,057,582 - 19,072,573 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1219,057,587 - 19,068,577 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1220,212,788 - 20,223,763 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01220,825,672 - 20,836,647 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01219,889,999 - 19,900,974 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01222,127,387 - 22,138,436 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,127,393 - 22,138,382 (-)Ensemblrn6Rnor6.0
Rnor_5.01224,144,400 - 24,155,794 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41219,694,434 - 19,705,423 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1220,862,982 - 20,873,971 (-)NCBICelera
RGSC_v3.11219,680,492 - 19,694,990 (+)NCBI
Cytogenetic Map12q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
plasma membrane  (IEA,ISO)
PML body  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:16449650  


Genomics

Comparative Map Data
Lrch4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81224,694,364 - 24,709,354 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1224,694,370 - 24,706,412 (-)EnsemblGRCr8
mRatBN7.21219,057,582 - 19,072,573 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1219,057,587 - 19,068,577 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1220,212,788 - 20,223,763 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01220,825,672 - 20,836,647 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01219,889,999 - 19,900,974 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01222,127,387 - 22,138,436 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,127,393 - 22,138,382 (-)Ensemblrn6Rnor6.0
Rnor_5.01224,144,400 - 24,155,794 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41219,694,434 - 19,705,423 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1220,862,982 - 20,873,971 (-)NCBICelera
RGSC_v3.11219,680,492 - 19,694,990 (+)NCBI
Cytogenetic Map12q12NCBI
LRCH4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,574,011 - 100,586,129 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,574,011 - 100,586,161 (-)Ensemblhg38GRCh38
GRCh377100,171,634 - 100,183,752 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367100,009,570 - 100,021,712 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34799,814,505 - 99,828,437NCBI
Celera794,901,433 - 94,913,573 (-)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,803,306 - 94,815,446 (-)NCBIHuRef
CHM1_17100,102,208 - 100,114,348 (-)NCBICHM1_1
T2T-CHM13v2.07101,814,094 - 101,826,212 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,531,269 - 99,543,409 (-)NCBI
Lrch4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,627,385 - 137,639,361 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5137,627,383 - 137,639,361 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385137,629,123 - 137,641,099 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,629,121 - 137,641,099 (+)Ensemblmm10GRCm38
MGSCv375138,070,351 - 138,082,327 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365137,858,971 - 137,870,290 (+)NCBIMGSCv36mm8
Celera5134,612,428 - 134,624,405 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.59NCBI
Lrch4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955573315,766 - 331,477 (+)Ensembl
ChiLan1.0NW_004955573315,764 - 327,833 (+)NCBIChiLan1.0ChiLan1.0
LRCH4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,486,110 - 118,497,506 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,750,110 - 166,762,138 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,601,158 - 92,613,274 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17106,003,656 - 106,015,243 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7106,004,101 - 106,015,061 (-)EnsemblpanPan2panpan1.1
LRCH4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.169,088,815 - 9,113,629 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl69,020,415 - 9,113,368 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha610,806,833 - 10,818,240 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.069,036,627 - 9,048,043 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl69,036,758 - 9,048,037 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.168,889,127 - 8,899,777 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.068,866,811 - 8,878,214 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.069,049,047 - 9,060,456 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lrch4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,392,861 - 133,404,407 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936543632,255 - 643,686 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936543632,255 - 643,639 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRCH4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,499,285 - 8,511,262 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.138,497,456 - 8,511,361 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.237,842,384 - 7,847,191 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LRCH4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,627,666 - 12,639,312 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,627,712 - 12,638,228 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660703,665,463 - 3,677,188 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrch4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,491,837 - 16,503,491 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474016,491,804 - 16,503,682 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Lrch4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11616,384,731 - 16,395,731 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Lrch4
102 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:308
Count of miRNA genes:184
Interacting mature miRNAs:217
Transcripts:ENSRNOT00000001899
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12592191825247790Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)122013902826430640Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)12129775522Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12128133365Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)121223300030490641Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121746497946784661Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12128606299Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121874946936488809Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)12124849755Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121874946934312613Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
2303568Bw88Body weight QTL 883body mass (VT:0001259)body weight (CMO:0000012)12128606299Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12790162533938215Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743833700556Rat

Markers in Region
RH141548  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21219,058,182 - 19,058,390 (+)MAPPERmRatBN7.2
Rnor_6.01222,127,988 - 22,128,195NCBIRnor6.0
Rnor_5.01224,145,364 - 24,145,571UniSTSRnor5.0
RGSC_v3.41219,704,621 - 19,704,828UniSTSRGSC3.4
Celera1220,863,577 - 20,863,784UniSTS
Cytogenetic Map12q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001127551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006249175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039089581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063271483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC107410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC166781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000001899   ⟹   ENSRNOP00000001899
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1224,694,370 - 24,705,359 (-)Ensembl
mRatBN7.2 Ensembl1219,057,588 - 19,068,577 (-)Ensembl
Rnor_6.0 Ensembl1222,127,393 - 22,138,382 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094748   ⟹   ENSRNOP00000095598
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1224,694,370 - 24,704,486 (-)Ensembl
mRatBN7.2 Ensembl1219,057,587 - 19,067,505 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097090   ⟹   ENSRNOP00000092129
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1224,694,370 - 24,705,359 (-)Ensembl
mRatBN7.2 Ensembl1219,057,588 - 19,068,577 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115724   ⟹   ENSRNOP00000093054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1224,694,370 - 24,706,412 (-)Ensembl
RefSeq Acc Id: NM_001127551   ⟹   NP_001121023
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,370 - 24,705,359 (-)NCBI
mRatBN7.21219,057,588 - 19,068,577 (-)NCBI
Rnor_6.01222,127,393 - 22,138,382 (-)NCBI
Rnor_5.01224,144,400 - 24,155,794 (-)NCBI
RGSC_v3.41219,694,434 - 19,705,423 (+)RGD
Celera1220,862,982 - 20,873,971 (-)RGD
Sequence:
RefSeq Acc Id: XM_006249175   ⟹   XP_006249237
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,705,457 (-)NCBI
mRatBN7.21219,057,587 - 19,068,604 (-)NCBI
Rnor_6.01222,127,387 - 22,138,436 (-)NCBI
Rnor_5.01224,144,400 - 24,155,794 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598386   ⟹   XP_017453875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,705,408 (-)NCBI
mRatBN7.21219,057,582 - 19,068,604 (-)NCBI
Rnor_6.01222,127,387 - 22,138,419 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039089577   ⟹   XP_038945505
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,705,409 (-)NCBI
mRatBN7.21219,057,587 - 19,068,581 (-)NCBI
RefSeq Acc Id: XM_039089578   ⟹   XP_038945506
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,705,409 (-)NCBI
mRatBN7.21219,057,587 - 19,068,581 (-)NCBI
RefSeq Acc Id: XM_039089579   ⟹   XP_038945507
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,705,411 (-)NCBI
mRatBN7.21219,057,587 - 19,068,581 (-)NCBI
RefSeq Acc Id: XM_039089580   ⟹   XP_038945508
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,705,408 (-)NCBI
mRatBN7.21219,057,582 - 19,068,581 (-)NCBI
RefSeq Acc Id: XM_039089581   ⟹   XP_038945509
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,704,436 (-)NCBI
mRatBN7.21219,057,587 - 19,068,297 (-)NCBI
RefSeq Acc Id: XM_063271475   ⟹   XP_063127545
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,705,408 (-)NCBI
RefSeq Acc Id: XM_063271476   ⟹   XP_063127546
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,705,408 (-)NCBI
RefSeq Acc Id: XM_063271477   ⟹   XP_063127547
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,705,408 (-)NCBI
RefSeq Acc Id: XM_063271478   ⟹   XP_063127548
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,705,408 (-)NCBI
RefSeq Acc Id: XM_063271479   ⟹   XP_063127549
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,705,407 (-)NCBI
RefSeq Acc Id: XM_063271480   ⟹   XP_063127550
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,705,407 (-)NCBI
RefSeq Acc Id: XM_063271481   ⟹   XP_063127551
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,704,449 (-)NCBI
RefSeq Acc Id: XM_063271482   ⟹   XP_063127552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,705,232 (-)NCBI
RefSeq Acc Id: XM_063271483   ⟹   XP_063127553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81224,694,364 - 24,709,354 (-)NCBI
RefSeq Acc Id: NP_001121023   ⟸   NM_001127551
- UniProtKB: B2RYH6 (UniProtKB/TrEMBL),   E9PSW6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249237   ⟸   XM_006249175
- Peptide Label: isoform X3
- UniProtKB: A6J009 (UniProtKB/TrEMBL),   B2RYH6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453875   ⟸   XM_017598386
- Peptide Label: isoform X10
- Sequence:
Ensembl Acc Id: ENSRNOP00000001899   ⟸   ENSRNOT00000001899
RefSeq Acc Id: XP_038945508   ⟸   XM_039089580
- Peptide Label: isoform X6
- UniProtKB: B2RYH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945507   ⟸   XM_039089579
- Peptide Label: isoform X4
- UniProtKB: B2RYH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945506   ⟸   XM_039089578
- Peptide Label: isoform X2
- UniProtKB: B2RYH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945505   ⟸   XM_039089577
- Peptide Label: isoform X1
- UniProtKB: B2RYH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038945509   ⟸   XM_039089581
- Peptide Label: isoform X12
- UniProtKB: B2RYH6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000095598   ⟸   ENSRNOT00000094748
Ensembl Acc Id: ENSRNOP00000092129   ⟸   ENSRNOT00000097090
RefSeq Acc Id: XP_063127553   ⟸   XM_063271483
- Peptide Label: isoform X15
RefSeq Acc Id: XP_063127546   ⟸   XM_063271476
- Peptide Label: isoform X7
- UniProtKB: B2RYH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127545   ⟸   XM_063271475
- Peptide Label: isoform X5
- UniProtKB: B2RYH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127548   ⟸   XM_063271478
- Peptide Label: isoform X9
- UniProtKB: B2RYH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127547   ⟸   XM_063271477
- Peptide Label: isoform X8
- UniProtKB: B2RYH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127550   ⟸   XM_063271480
- Peptide Label: isoform X13
- UniProtKB: B2RYH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127549   ⟸   XM_063271479
- Peptide Label: isoform X11
- UniProtKB: B2RYH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127552   ⟸   XM_063271482
- Peptide Label: isoform X15
RefSeq Acc Id: XP_063127551   ⟸   XM_063271481
- Peptide Label: isoform X14
- UniProtKB: A0A8I6APG5 (UniProtKB/TrEMBL),   B2RYH6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000093054   ⟸   ENSRNOT00000115724
Protein Domains
Calponin-homology (CH)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PSW6-F1-model_v2 AlphaFold E9PSW6 1-686 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698513
Promoter ID:EPDNEW_R9037
Type:multiple initiation site
Name:Lrch4_1
Description:leucine rich repeats and calponin homology domain containing4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01222,138,378 - 22,138,438EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306145 AgrOrtholog
BioCyc Gene G2FUF-19713 BioCyc
Ensembl Genes ENSRNOG00000001402 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001899 ENTREZGENE
  ENSRNOT00000001899.7 UniProtKB/TrEMBL
  ENSRNOT00000094748 ENTREZGENE
  ENSRNOT00000094748.2 UniProtKB/TrEMBL
  ENSRNOT00000097090.2 UniProtKB/TrEMBL
  ENSRNOT00000115724 ENTREZGENE
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7934984 IMAGE-MGC_LOAD
InterPro Calponin-like_dom_sf UniProtKB/TrEMBL
  CH-domain UniProtKB/TrEMBL
  L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_domain-containing UniProtKB/TrEMBL
KEGG Report rno:360779 UniProtKB/TrEMBL
MGC_CLONE MGC:188561 IMAGE-MGC_LOAD
NCBI Gene 360779 ENTREZGENE
PANTHER LEUCINE RICH REPEATS AND CALPONIN HOMOLOGY DOMAIN CONTAINING 4 UniProtKB/TrEMBL
  PTHR48051 UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
  PF00307 UniProtKB/TrEMBL
PhenoGen Lrch4 PhenoGen
PRINTS LEURICHRPT UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
  PS50021 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001402 RatGTEx
SMART LRR_BAC UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  SM00033 UniProtKB/TrEMBL
Superfamily-SCOP Calponin-homology UniProtKB/TrEMBL
  L domain-like UniProtKB/TrEMBL
UniProt A0A8I6APG5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJI5_RAT UniProtKB/TrEMBL
  A6J009 ENTREZGENE, UniProtKB/TrEMBL
  B2RYH6 ENTREZGENE, UniProtKB/TrEMBL
  E9PSW6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-15 Lrch4  leucine rich repeats and calponin homology domain containing 4  Lrch4  leucine-rich repeats and calponin homology (CH) domain containing 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Lrch4  leucine-rich repeats and calponin homology (CH) domain containing 4   Lrch4_predicted  leucine-rich repeats and calponin homology (CH) domain containing 4 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Lrch4_predicted  leucine-rich repeats and calponin homology (CH) domain containing 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED