Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Atf7ip | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Atf7ip (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of ATF7IP mRNA] | CTD | PMID:22206623 | Atf7ip | Rat | 17beta-estradiol | increases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Estradiol results in increased expression of ATF7IP mRNA | CTD | PMID:19429434 | Atf7ip | Rat | 17beta-estradiol | decreases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Estradiol results in decreased expression of ATF7IP mRNA | CTD | PMID:31614463 | Atf7ip | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Atf7ip (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ATF7IP mRNA | CTD | PMID:21570461 | Atf7ip | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ATF7IP mRNA | CTD | PMID:33387578 | Atf7ip | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ATF7IP mRNA | CTD | PMID:34747641 | Atf7ip | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of ATF7IP mRNA | CTD | PMID:21346803 | Atf7ip | Rat | 2-amino-2-deoxy-D-glucopyranose | increases expression | ISO | Atf7ip (Mus musculus) | 6480464 | Glucosamine results in increased expression of ATF7IP mRNA | CTD | PMID:17178593 | Atf7ip | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Atf7ip (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of ATF7IP mRNA | CTD | PMID:26251327 | Atf7ip | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of ATF7IP mRNA | CTD | PMID:30047161 | Atf7ip | Rat | acrolein | multiple interactions | ISO | ATF7IP (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Atf7ip | Rat | aflatoxin B1 | decreases methylation | ISO | ATF7IP (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ATF7IP gene | CTD | PMID:27153756 | Atf7ip | Rat | aldehydo-D-glucosamine | increases expression | ISO | Atf7ip (Mus musculus) | 6480464 | Glucosamine results in increased expression of ATF7IP mRNA | CTD | PMID:17178593 | Atf7ip | Rat | alpha-pinene | multiple interactions | ISO | ATF7IP (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Atf7ip | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of ATF7IP mRNA | CTD | PMID:30047161|PMID:38685447 | Atf7ip | Rat | aristolochic acid A | decreases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ATF7IP mRNA | CTD | PMID:33212167 | Atf7ip | Rat | arsane | affects methylation | ISO | ATF7IP (Homo sapiens) | 6480464 | Arsenic affects the methylation of ATF7IP gene | CTD | PMID:25304211 | Atf7ip | Rat | arsane | multiple interactions | ISO | ATF7IP (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ATF7IP more ... | CTD | PMID:39836092 | Atf7ip | Rat | arsenic atom | affects methylation | ISO | ATF7IP (Homo sapiens) | 6480464 | Arsenic affects the methylation of ATF7IP gene | CTD | PMID:25304211 | Atf7ip | Rat | arsenic atom | multiple interactions | ISO | ATF7IP (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ATF7IP more ... | CTD | PMID:39836092 | Atf7ip | Rat | arsenite(3-) | multiple interactions | ISO | ATF7IP (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to ATF7IP mRNA] | CTD | PMID:32406909 | Atf7ip | Rat | atrazine | increases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Atrazine results in increased expression of ATF7IP mRNA | CTD | PMID:22378314 | Atf7ip | Rat | benzo[a]pyrene | affects methylation | ISO | ATF7IP (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ATF7IP 5' UTR | CTD | PMID:27901495 | Atf7ip | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ATF7IP mRNA | CTD | PMID:20018196 | Atf7ip | Rat | beta-D-glucosamine | increases expression | ISO | Atf7ip (Mus musculus) | 6480464 | Glucosamine results in increased expression of ATF7IP mRNA | CTD | PMID:17178593 | Atf7ip | Rat | bisphenol A | increases expression | ISO | Atf7ip (Mus musculus) | 6480464 | bisphenol A results in increased expression of ATF7IP mRNA | CTD | PMID:26063408 | Atf7ip | Rat | bisphenol A | decreases methylation | ISO | ATF7IP (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of ATF7IP gene | CTD | PMID:31601247 | Atf7ip | Rat | bisphenol A | decreases expression | ISO | Atf7ip (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ATF7IP mRNA | CTD | PMID:33221593 | Atf7ip | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ATF7IP mRNA | CTD | PMID:30816183 | Atf7ip | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ATF7IP mRNA | CTD | PMID:25181051 | Atf7ip | Rat | bisphenol F | increases expression | ISO | Atf7ip (Mus musculus) | 6480464 | bisphenol F results in increased expression of ATF7IP mRNA | CTD | PMID:38685157 | Atf7ip | Rat | Butylbenzyl phthalate | increases methylation | ISO | Atf7ip (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of ATF7IP intron | CTD | PMID:28392331 | Atf7ip | Rat | cadmium dichloride | increases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of ATF7IP mRNA | CTD | PMID:38174414 | Atf7ip | Rat | caffeine | affects phosphorylation | ISO | ATF7IP (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of ATF7IP protein | CTD | PMID:35688186 | Atf7ip | Rat | carbon nanotube | decreases expression | ISO | Atf7ip (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of ATF7IP mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681 | Atf7ip | Rat | CGP 52608 | multiple interactions | ISO | ATF7IP (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ATF7IP gene] | CTD | PMID:28238834 | Atf7ip | Rat | chlorpyrifos | decreases expression | ISO | Atf7ip (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of ATF7IP mRNA | CTD | PMID:37019170 | Atf7ip | Rat | choline | multiple interactions | ISO | Atf7ip (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... | CTD | PMID:20938992 | Atf7ip | Rat | coumarin | decreases phosphorylation | ISO | ATF7IP (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of ATF7IP protein | CTD | PMID:35688186 | Atf7ip | Rat | crocidolite asbestos | affects expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Asbestos, Crocidolite affects the expression of ATF7IP mRNA | CTD | PMID:17331233 | Atf7ip | Rat | Dibutyl phosphate | affects expression | ISO | ATF7IP (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of ATF7IP mRNA | CTD | PMID:37042841 | Atf7ip | Rat | dorsomorphin | multiple interactions | ISO | ATF7IP (Homo sapiens) | 6480464 | [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Atf7ip | Rat | doxorubicin | decreases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of ATF7IP mRNA | CTD | PMID:29803840 | Atf7ip | Rat | doxorubicin | increases expression | ISO | Atf7ip (Mus musculus) | 6480464 | Doxorubicin results in increased expression of ATF7IP mRNA | CTD | PMID:39631538 | Atf7ip | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of ATF7IP mRNA | CTD | PMID:24136188 | Atf7ip | Rat | folic acid | multiple interactions | ISO | Atf7ip (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... | CTD | PMID:20938992|PMID:22206623 | Atf7ip | Rat | FR900359 | affects phosphorylation | ISO | ATF7IP (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of ATF7IP protein | CTD | PMID:37730182 | Atf7ip | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of ATF7IP gene | CTD | PMID:22079235 | Atf7ip | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of ATF7IP mRNA | CTD | PMID:22061828 | Atf7ip | Rat | GSK-J4 | decreases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | GSK-J4 results in decreased expression of ATF7IP mRNA | CTD | PMID:29301935 | Atf7ip | Rat | hexadecanoic acid | decreases phosphorylation | ISO | ATF7IP (Homo sapiens) | 6480464 | Palmitic Acid results in decreased phosphorylation of ATF7IP protein | CTD | PMID:28073184 | Atf7ip | Rat | inulin | multiple interactions | ISO | Atf7ip (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ATF7IP mRNA | CTD | PMID:36331819 | Atf7ip | Rat | kainic acid | decreases expression | EXP | | 6480464 | Kainic Acid results in decreased expression of ATF7IP mRNA | CTD | PMID:19700661 | Atf7ip | Rat | L-methionine | multiple interactions | ISO | Atf7ip (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... | CTD | PMID:20938992 | Atf7ip | Rat | leflunomide | increases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | leflunomide results in increased expression of ATF7IP mRNA | CTD | PMID:28988120 | Atf7ip | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of ATF7IP mRNA | CTD | PMID:30047161 | Atf7ip | Rat | methotrexate | affects expression | ISO | Atf7ip (Mus musculus) | 6480464 | Methotrexate affects the expression of ATF7IP mRNA | CTD | PMID:18502557 | Atf7ip | Rat | methylmercury chloride | decreases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of ATF7IP mRNA | CTD | PMID:26272509 | Atf7ip | Rat | methylmercury chloride | multiple interactions | ISO | ATF7IP (Homo sapiens) | 6480464 | [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Atf7ip | Rat | N-ethyl-N-nitrosourea | increases mutagenesis | ISO | Atf7ip (Mus musculus) | 6480464 | Ethylnitrosourea results in increased mutagenesis of ATF7IP mRNA | CTD | PMID:27776689 | Atf7ip | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ATF7IP mRNA | CTD | PMID:25729387 | Atf7ip | Rat | ozone | multiple interactions | ISO | ATF7IP (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Atf7ip | Rat | paracetamol | affects expression | ISO | Atf7ip (Mus musculus) | 6480464 | Acetaminophen affects the expression of ATF7IP mRNA | CTD | PMID:17562736 | Atf7ip | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of ATF7IP mRNA | CTD | PMID:33387578 | Atf7ip | Rat | paracetamol | increases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ATF7IP mRNA | CTD | PMID:21420995 | Atf7ip | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Atf7ip (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ATF7IP mRNA | CTD | PMID:36331819 | Atf7ip | Rat | PhIP | increases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ATF7IP mRNA | CTD | PMID:20816883 | Atf7ip | Rat | quercetin | decreases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Quercetin results in decreased expression of ATF7IP mRNA | CTD | PMID:21632981 | Atf7ip | Rat | raloxifene | increases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Raloxifene Hydrochloride results in increased expression of ATF7IP mRNA | CTD | PMID:19429434 | Atf7ip | Rat | resorcinol | decreases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | resorcinol results in decreased expression of ATF7IP mRNA | CTD | PMID:22623647 | Atf7ip | Rat | SB 431542 | multiple interactions | ISO | ATF7IP (Homo sapiens) | 6480464 | [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Atf7ip | Rat | silver atom | increases expression | ISO | Atf7ip (Mus musculus) | 6480464 | Silver results in increased expression of ATF7IP mRNA | CTD | PMID:27131904 | Atf7ip | Rat | silver(0) | increases expression | ISO | Atf7ip (Mus musculus) | 6480464 | Silver results in increased expression of ATF7IP mRNA | CTD | PMID:27131904 | Atf7ip | Rat | sodium arsenite | increases expression | ISO | Atf7ip (Mus musculus) | 6480464 | sodium arsenite results in increased expression of ATF7IP mRNA | CTD | PMID:19822182 | Atf7ip | Rat | sodium arsenite | multiple interactions | ISO | ATF7IP (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ATF7IP more ... | CTD | PMID:39836092 | Atf7ip | Rat | sodium arsenite | increases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of ATF7IP mRNA | CTD | PMID:38568856 | Atf7ip | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of ATF7IP mRNA | CTD | PMID:30047161 | Atf7ip | Rat | sunitinib | decreases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of ATF7IP mRNA | CTD | PMID:31533062 | Atf7ip | Rat | tamoxifen | increases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Tamoxifen results in increased expression of ATF7IP mRNA | CTD | PMID:19429434 | Atf7ip | Rat | testosterone | decreases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Testosterone results in decreased expression of ATF7IP mRNA | CTD | PMID:33359661 | Atf7ip | Rat | thimerosal | increases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Thimerosal results in increased expression of ATF7IP mRNA | CTD | PMID:27188386 | Atf7ip | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ATF7IP mRNA | CTD | PMID:34492290 | Atf7ip | Rat | thiram | increases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Thiram results in increased expression of ATF7IP mRNA | CTD | PMID:38568856 | Atf7ip | Rat | titanium dioxide | decreases expression | ISO | Atf7ip (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of ATF7IP mRNA | CTD | PMID:27760801 | Atf7ip | Rat | titanium dioxide | increases methylation | ISO | Atf7ip (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of ATF7IP gene | CTD | PMID:35295148 | Atf7ip | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ATF7IP mRNA | CTD | PMID:25729387 | Atf7ip | Rat | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of ATF7IP mRNA | CTD | PMID:25729387 | Atf7ip | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of ATF7IP mRNA | CTD | PMID:33387578 | Atf7ip | Rat | trichostatin A | increases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | trichostatin A results in increased expression of ATF7IP mRNA | CTD | PMID:24935251|PMID:26272509 | Atf7ip | Rat | trichostatin A | multiple interactions | ISO | ATF7IP (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Atf7ip | Rat | triptonide | increases expression | ISO | Atf7ip (Mus musculus) | 6480464 | triptonide results in increased expression of ATF7IP mRNA | CTD | PMID:33045310 | Atf7ip | Rat | troglitazone | decreases expression | ISO | Atf7ip (Mus musculus) | 6480464 | troglitazone results in decreased expression of ATF7IP mRNA | CTD | PMID:28973697 | Atf7ip | Rat | tungsten | decreases expression | ISO | Atf7ip (Mus musculus) | 6480464 | Tungsten results in decreased expression of ATF7IP mRNA | CTD | PMID:30912803 | Atf7ip | Rat | urethane | decreases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Urethane results in decreased expression of ATF7IP mRNA | CTD | PMID:28818685 | Atf7ip | Rat | valproic acid | decreases expression | ISO | ATF7IP (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ATF7IP mRNA | CTD | PMID:23179753 | Atf7ip | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of ATF7IP mRNA | CTD | PMID:18042343 | Atf7ip | Rat | zinc atom | multiple interactions | ISO | ATF7IP (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of ATF7IP mRNA | CTD | PMID:18593933 | Atf7ip | Rat | zinc(0) | multiple interactions | ISO | ATF7IP (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of ATF7IP mRNA | CTD | PMID:18593933 | | |||||||||






















