Hdac10 (histone deacetylase 10) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Hdac10 (histone deacetylase 10) Rattus norvegicus
Analyze
Symbol: Hdac10
Name: histone deacetylase 10
RGD ID: 1305874
Description: Predicted to enable histone deacetylase activity; histone deacetylase binding activity; and zinc ion binding activity. Involved in oligodendrocyte development. Predicted to be located in nucleoplasm. Predicted to be part of histone deacetylase complex. Predicted to be active in cytosol. Orthologous to human HDAC10 (histone deacetylase 10); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: HD10; LOC362981; polyamine deacetylase HDAC10
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87122,078,768 - 122,084,457 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7122,078,768 - 122,083,870 (-)EnsemblGRCr8
mRatBN7.27120,199,126 - 120,205,850 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7120,199,129 - 120,204,228 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7121,950,152 - 121,955,255 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07124,176,317 - 124,181,420 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07124,139,323 - 124,144,426 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07130,102,335 - 130,109,036 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7130,102,347 - 130,107,437 (-)Ensemblrn6Rnor6.0
Rnor_5.07129,788,051 - 129,794,135 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47127,423,736 - 127,428,838 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7116,673,021 - 116,678,123 (-)NCBICelera
RGSC_v3.17127,459,992 - 127,462,839 (-)NCBI
Cytogenetic Map7q34NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO)
cytosol  (IBA,ISO)
histone deacetylase complex  (ISO)
nucleoplasm  (ISO)
nucleus  (IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Histone deacetylase 11 regulates oligodendrocyte-specific gene expression and cell development in OL-1 oligodendroglia cells. Liu H, etal., Glia. 2009 Jan 1;57(1):1-12.
4. Physical and functional HAT/HDAC interplay regulates protein acetylation balance. Peserico A and Simone C, J Biomed Biotechnol. 2011;2011:371832. doi: 10.1155/2011/371832. Epub 2010 Dec 5.
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11726666   PMID:11739383   PMID:11861901   PMID:15489334   PMID:17172643   PMID:21247901   PMID:23801752   PMID:26221039   PMID:28516954   PMID:32112918   PMID:32360748  


Genomics

Comparative Map Data
Hdac10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87122,078,768 - 122,084,457 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7122,078,768 - 122,083,870 (-)EnsemblGRCr8
mRatBN7.27120,199,126 - 120,205,850 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7120,199,129 - 120,204,228 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7121,950,152 - 121,955,255 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07124,176,317 - 124,181,420 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07124,139,323 - 124,144,426 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07130,102,335 - 130,109,036 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7130,102,347 - 130,107,437 (-)Ensemblrn6Rnor6.0
Rnor_5.07129,788,051 - 129,794,135 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47127,423,736 - 127,428,838 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7116,673,021 - 116,678,123 (-)NCBICelera
RGSC_v3.17127,459,992 - 127,462,839 (-)NCBI
Cytogenetic Map7q34NCBI
HDAC10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382250,245,183 - 50,251,265 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2250,245,183 - 50,251,405 (-)Ensemblhg38GRCh38
GRCh372250,683,612 - 50,689,694 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362249,025,739 - 49,031,941 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342248,986,071 - 48,992,271NCBI
Celera2234,558,514 - 34,564,737 (-)NCBICelera
Cytogenetic Map22q13.33NCBI
HuRef2233,581,335 - 33,587,801 (-)NCBIHuRef
CHM1_12250,642,365 - 50,648,588 (-)NCBICHM1_1
T2T-CHM13v2.02250,752,185 - 50,758,268 (-)NCBIT2T-CHM13v2.0
Hdac10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391589,007,506 - 89,012,903 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1589,007,510 - 89,012,903 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381589,123,303 - 89,128,700 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1589,123,307 - 89,128,700 (-)Ensemblmm10GRCm38
MGSCv371588,953,733 - 88,959,130 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361588,951,071 - 88,956,393 (-)NCBIMGSCv36mm8
Celera1591,251,865 - 91,257,263 (-)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1544.64NCBI
Hdac10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541333,272,714 - 33,277,686 (-)Ensembl
ChiLan1.0NW_00495541333,272,600 - 33,277,893 (-)NCBIChiLan1.0ChiLan1.0
HDAC10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22360,150,932 - 60,158,556 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12262,837,088 - 62,844,697 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02230,473,753 - 30,481,369 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12249,473,369 - 49,479,251 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2249,473,369 - 49,479,216 (-)EnsemblpanPan2panpan1.1
HDAC10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11016,996,307 - 17,001,365 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1016,995,762 - 17,078,262 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1016,974,507 - 16,979,565 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01017,723,533 - 17,728,591 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1017,722,764 - 17,728,591 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11017,447,560 - 17,452,618 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01017,770,649 - 17,775,707 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01017,902,859 - 17,907,917 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hdac10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945562,006 - 567,709 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936629562,022 - 567,822 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936629562,038 - 567,709 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HDAC10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5439,808 - 445,334 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.15439,142 - 445,337 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25110,662,633 - 110,668,163 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HDAC10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11932,735,091 - 32,741,200 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1932,735,406 - 32,740,817 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604592,613,492 - 92,620,124 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hdac10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624752518,563 - 524,497 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Hdac10
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11258,427,135 - 258,432,546 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hdac10
38 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:99
Count of miRNA genes:85
Interacting mature miRNAs:90
Transcripts:ENSRNOT00000055865
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7121393075137014596Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7119280025135560836Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7115313999136544683Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
1582240Sffal1Serum free fatty acids level QTL 13.40.0021blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)7118556868125929417Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)7116269196132020414Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
AW548891  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27120,199,630 - 120,199,757 (+)MAPPERmRatBN7.2
Rnor_6.07130,102,840 - 130,102,966NCBIRnor6.0
Rnor_5.07129,788,629 - 129,788,755UniSTSRnor5.0
RGSC_v3.47127,424,241 - 127,424,367UniSTSRGSC3.4
Celera7116,673,526 - 116,673,652UniSTS
Cytogenetic Map7q34UniSTS
RH139917  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27120,200,013 - 120,200,224 (+)MAPPERmRatBN7.2
Rnor_6.07130,103,223 - 130,103,433NCBIRnor6.0
Rnor_5.07129,789,012 - 129,789,222UniSTSRnor5.0
RGSC_v3.47127,424,624 - 127,424,834UniSTSRGSC3.4
Celera7116,673,909 - 116,674,119UniSTS
RH 3.4 Map7958.3UniSTS
Cytogenetic Map7q34UniSTS
RH128844  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27120,206,034 - 120,206,219 (+)MAPPERmRatBN7.2
Rnor_6.07130,109,244 - 130,109,428NCBIRnor6.0
Rnor_5.07129,795,033 - 129,795,217UniSTSRnor5.0
RGSC_v3.47127,430,645 - 127,430,829UniSTSRGSC3.4
Celera7116,679,930 - 116,680,114UniSTS
RH 3.4 Map7958.5UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001035000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001414972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC118923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC092573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000055865   ⟹   ENSRNOP00000052717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7122,078,771 - 122,083,870 (-)Ensembl
mRatBN7.2 Ensembl7120,199,129 - 120,204,228 (-)Ensembl
Rnor_6.0 Ensembl7130,102,347 - 130,107,437 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113351   ⟹   ENSRNOP00000093025
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7122,078,771 - 122,083,870 (-)Ensembl
mRatBN7.2 Ensembl7120,199,129 - 120,204,228 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118109   ⟹   ENSRNOP00000088972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7122,078,768 - 122,083,846 (-)Ensembl
mRatBN7.2 Ensembl7120,199,130 - 120,204,221 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000124238   ⟹   ENSRNOP00000109513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7122,078,768 - 122,083,846 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000134094   ⟹   ENSRNOP00000099349
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7122,078,768 - 122,083,846 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000143059   ⟹   ENSRNOP00000108360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7122,078,768 - 122,083,846 (-)Ensembl
RefSeq Acc Id: NM_001035000   ⟹   NP_001030172
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,078,768 - 122,083,846 (-)NCBI
mRatBN7.27120,199,126 - 120,204,204 (-)NCBI
Rnor_6.07130,102,335 - 130,107,437 (-)NCBI
Rnor_5.07129,788,051 - 129,794,135 (-)NCBI
RGSC_v3.47127,423,736 - 127,428,838 (-)RGD
Celera7116,673,021 - 116,678,123 (-)RGD
Sequence:
RefSeq Acc Id: NM_001414972   ⟹   NP_001401901
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,078,768 - 122,083,846 (-)NCBI
mRatBN7.27120,199,126 - 120,204,204 (-)NCBI
RefSeq Acc Id: XM_006242219   ⟹   XP_006242281
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,078,772 - 122,084,457 (-)NCBI
mRatBN7.27120,199,126 - 120,205,850 (-)NCBI
Rnor_6.07130,102,339 - 130,109,036 (-)NCBI
Rnor_5.07129,788,051 - 129,794,135 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079624   ⟹   XP_038935552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,078,772 - 122,084,457 (-)NCBI
mRatBN7.27120,199,126 - 120,205,850 (-)NCBI
RefSeq Acc Id: XM_039079625   ⟹   XP_038935553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,078,772 - 122,084,457 (-)NCBI
mRatBN7.27120,199,126 - 120,205,850 (-)NCBI
RefSeq Acc Id: XM_039079626   ⟹   XP_038935554
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,078,772 - 122,082,598 (-)NCBI
mRatBN7.27120,199,126 - 120,202,944 (-)NCBI
RefSeq Acc Id: XM_039079627   ⟹   XP_038935555
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,078,772 - 122,082,689 (-)NCBI
mRatBN7.27120,199,126 - 120,203,048 (-)NCBI
RefSeq Acc Id: XM_039079628   ⟹   XP_038935556
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,078,772 - 122,082,598 (-)NCBI
mRatBN7.27120,199,126 - 120,202,944 (-)NCBI
RefSeq Acc Id: XM_039079629   ⟹   XP_038935557
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,078,772 - 122,082,598 (-)NCBI
mRatBN7.27120,199,126 - 120,202,944 (-)NCBI
RefSeq Acc Id: XM_039079630   ⟹   XP_038935558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,078,772 - 122,082,598 (-)NCBI
mRatBN7.27120,199,126 - 120,202,944 (-)NCBI
RefSeq Acc Id: XM_039079631   ⟹   XP_038935559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,078,772 - 122,082,598 (-)NCBI
mRatBN7.27120,199,126 - 120,202,944 (-)NCBI
RefSeq Acc Id: XM_039079632   ⟹   XP_038935560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,078,772 - 122,082,042 (-)NCBI
mRatBN7.27120,199,126 - 120,202,402 (-)NCBI
RefSeq Acc Id: XM_039079633   ⟹   XP_038935561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,080,701 - 122,084,457 (-)NCBI
mRatBN7.27120,201,049 - 120,205,850 (-)NCBI
RefSeq Acc Id: XM_039079634   ⟹   XP_038935562
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,080,749 - 122,084,457 (-)NCBI
mRatBN7.27120,201,107 - 120,205,850 (-)NCBI
RefSeq Acc Id: NP_001030172   ⟸   NM_001035000
- Peptide Label: isoform 2
- UniProtKB: Q569C4 (UniProtKB/Swiss-Prot),   A0A8I6AHE1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242281   ⟸   XM_006242219
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AHE1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000052717   ⟸   ENSRNOT00000055865
RefSeq Acc Id: XP_038935553   ⟸   XM_039079625
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AHE1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935552   ⟸   XM_039079624
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AHE1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935555   ⟸   XM_039079627
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038935556   ⟸   XM_039079628
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038935559   ⟸   XM_039079631
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038935554   ⟸   XM_039079626
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038935558   ⟸   XM_039079630
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038935557   ⟸   XM_039079629
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038935560   ⟸   XM_039079632
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038935561   ⟸   XM_039079633
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038935562   ⟸   XM_039079634
- Peptide Label: isoform X9
Ensembl Acc Id: ENSRNOP00000093025   ⟸   ENSRNOT00000113351
Ensembl Acc Id: ENSRNOP00000088972   ⟸   ENSRNOT00000118109
RefSeq Acc Id: NP_001401901   ⟸   NM_001414972
- Peptide Label: isoform 1
- UniProtKB: A0A8I6A775 (UniProtKB/TrEMBL),   A6K7J6 (UniProtKB/TrEMBL),   A0A8I6AHE1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000108360   ⟸   ENSRNOT00000143059
Ensembl Acc Id: ENSRNOP00000109513   ⟸   ENSRNOT00000124238
Ensembl Acc Id: ENSRNOP00000099349   ⟸   ENSRNOT00000134094
Protein Domains
Histone deacetylase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q569C4-F1-model_v2 AlphaFold Q569C4 1-588 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695578
Promoter ID:EPDNEW_R6103
Type:initiation region
Name:Hdac10_1
Description:histone deacetylase 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07130,107,413 - 130,107,473EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305874 AgrOrtholog
BioCyc Gene G2FUF-32462 BioCyc
Ensembl Genes ENSRNOG00000031915 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000055865 ENTREZGENE
  ENSRNOT00000055865.4 UniProtKB/Swiss-Prot
  ENSRNOT00000118109 ENTREZGENE
  ENSRNOT00000134094 ENTREZGENE
  ENSRNOT00000143059 ENTREZGENE
Gene3D-CATH 3.40.800.20 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7323327 IMAGE-MGC_LOAD
InterPro HDAC_PDAC UniProtKB/Swiss-Prot
  His_deacetylse UniProtKB/Swiss-Prot
  His_deacetylse_dom UniProtKB/Swiss-Prot
  His_deacetylse_dom_sf UniProtKB/Swiss-Prot
  Ureohydrolase_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:362981 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108767 IMAGE-MGC_LOAD
NCBI Gene 362981 ENTREZGENE
PANTHER HISTONE DEACETYLASE HDAC1-RELATED UniProtKB/Swiss-Prot
  POLYAMINE DEACETYLASE HDAC10 UniProtKB/Swiss-Prot
Pfam Hist_deacetyl UniProtKB/Swiss-Prot
PhenoGen Hdac10 PhenoGen
PRINTS HDASUPER UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000031915 RatGTEx
Superfamily-SCOP SSF52768 UniProtKB/Swiss-Prot
UniProt A0A8I6A775 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AHE1 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L6Y1_RAT UniProtKB/TrEMBL
  A0ABK0LW74_RAT UniProtKB/TrEMBL
  A0ABK0LZ28_RAT UniProtKB/TrEMBL
  A6K7J6 ENTREZGENE, UniProtKB/TrEMBL
  HDA10_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Hdac10  histone deacetylase 10  Hdac10_predicted  histone deacetylase 10 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Hdac10_predicted  histone deacetylase 10 (predicted)      Symbol and Name status set to approved 70820 APPROVED