Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Lratd1 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Lratd1 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of FAM84A mRNA | CTD | PMID:22206623 | Lratd1 | Rat | 17beta-estradiol | multiple interactions | ISO | LRATD1 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of LRATD1 mRNA | CTD | PMID:30165855 | Lratd1 | Rat | 17beta-estradiol | decreases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of LRATD1 mRNA | CTD | PMID:31614463 | Lratd1 | Rat | 17beta-estradiol | increases expression | ISO | Lratd1 (Mus musculus) | 6480464 | Estradiol results in increased expression of LRATD1 mRNA | CTD | PMID:19484750 | Lratd1 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | affects expression | ISO | Lratd1 (Mus musculus) | 6480464 | 2,3',4,4',5-pentachlorobiphenyl affects the expression of LRATD1 mRNA | CTD | PMID:31388691 | Lratd1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LRATD1 mRNA | CTD | PMID:32109520 | Lratd1 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of LRATD1 mRNA | CTD | PMID:32109520 | Lratd1 | Rat | 2-palmitoylglycerol | increases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of LRATD1 mRNA | CTD | PMID:37199045 | Lratd1 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | LRATD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Lratd1 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Lratd1 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of LRATD1 exon | CTD | PMID:33297965 | Lratd1 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Lratd1 (Mus musculus) | 6480464 | bisphenol S affects the methylation of FAM84A gene | CTD | PMID:31683443 | Lratd1 | Rat | 5-fluorouracil | increases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | Fluorouracil results in increased expression of LRATD1 mRNA | CTD | PMID:24737281 | Lratd1 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of LRATD1 mRNA | CTD | PMID:28959563 | Lratd1 | Rat | aflatoxin B1 | decreases methylation | ISO | LRATD1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of LRATD1 gene | CTD | PMID:27153756 | Lratd1 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of FAM84A mRNA | CTD | PMID:35163327 | Lratd1 | Rat | antirheumatic drug | decreases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of LRATD1 mRNA | CTD | PMID:24449571 | Lratd1 | Rat | benzo[a]pyrene | decreases methylation | ISO | LRATD1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of FAM84A promoter | CTD | PMID:27901495 | Lratd1 | Rat | benzo[a]pyrene | decreases expression | ISO | Lratd1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of LRATD1 mRNA | CTD | PMID:19770486 | Lratd1 | Rat | benzo[a]pyrene | affects methylation | ISO | LRATD1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of FAM84A 3' UTR; Benzo(a)pyrene affects the methylation of FAM84A 5' more ... | CTD | PMID:27901495 | Lratd1 | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... | CTD | PMID:39150890 | Lratd1 | Rat | bisphenol A | multiple interactions | ISO | LRATD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Lratd1 | Rat | bisphenol A | increases expression | ISO | Lratd1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of LRATD1 mRNA | CTD | PMID:32156529 | Lratd1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of LRATD1 mRNA | CTD | PMID:25181051 | Lratd1 | Rat | bisphenol A | decreases expression | ISO | Lratd1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of FAM84A mRNA | CTD | PMID:30951980 | Lratd1 | Rat | bisphenol F | decreases expression | ISO | Lratd1 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of FAM84A mRNA | CTD | PMID:30951980 | Lratd1 | Rat | bisphenol F | multiple interactions | ISO | LRATD1 (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in decreased methylation of LRATD1 gene | CTD | PMID:31601247 | Lratd1 | Rat | butanal | increases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of LRATD1 mRNA | CTD | PMID:26079696 | Lratd1 | Rat | Butylbenzyl phthalate | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... | CTD | PMID:39150890 | Lratd1 | Rat | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of LRATD1 mRNA | CTD | PMID:19167457 | Lratd1 | Rat | cadmium dichloride | decreases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of FAM84A mRNA | CTD | PMID:38382870 | Lratd1 | Rat | cadmium dichloride | increases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of LRATD1 mRNA | CTD | PMID:38174414 | Lratd1 | Rat | calcitriol | increases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of LRATD1 mRNA | CTD | PMID:26485663 | Lratd1 | Rat | cefaloridine | increases expression | EXP | | 6480464 | Cephaloridine results in increased expression of LRATD1 mRNA | CTD | PMID:18500788 | Lratd1 | Rat | choline | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B more ... | CTD | PMID:33549593 | Lratd1 | Rat | chromium(6+) | multiple interactions | ISO | LRATD1 (Homo sapiens) | 6480464 | [zinc chromate results in increased abundance of chromium hexavalent ion] which results in increased expression more ... | CTD | PMID:38479592 | Lratd1 | Rat | copper atom | multiple interactions | ISO | LRATD1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of LRATD1 mRNA | CTD | PMID:20971185 | Lratd1 | Rat | copper atom | decreases expression | EXP | | 6480464 | Copper results in decreased expression of LRATD1 mRNA | CTD | PMID:30556269 | Lratd1 | Rat | copper(0) | multiple interactions | ISO | LRATD1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of LRATD1 mRNA | CTD | PMID:20971185 | Lratd1 | Rat | copper(0) | decreases expression | EXP | | 6480464 | Copper results in decreased expression of LRATD1 mRNA | CTD | PMID:30556269 | Lratd1 | Rat | cyanocob(III)alamin | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B more ... | CTD | PMID:33549593 | Lratd1 | Rat | dexamethasone | multiple interactions | ISO | LRATD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Lratd1 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of LRATD1 mRNA | CTD | PMID:21266533 | Lratd1 | Rat | dibutyl phthalate | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... | CTD | PMID:39150890 | Lratd1 | Rat | diethyl phthalate | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... | CTD | PMID:39150890 | Lratd1 | Rat | diisobutyl phthalate | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... | CTD | PMID:39150890 | Lratd1 | Rat | diisononyl phthalate | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ... | CTD | PMID:39150890 | Lratd1 | Rat | dorsomorphin | multiple interactions | ISO | LRATD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Lratd1 | Rat | doxorubicin | increases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of LRATD1 mRNA | CTD | PMID:30031762 | Lratd1 | Rat | entinostat | decreases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | entinostat results in decreased expression of LRATD1 mRNA | CTD | PMID:26272509 | Lratd1 | Rat | entinostat | multiple interactions | ISO | LRATD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Lratd1 | Rat | ethanol | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of LRATD1 mRNA | CTD | PMID:30319688 | Lratd1 | Rat | folic acid | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B more ... | CTD | PMID:33549593 | Lratd1 | Rat | fulvestrant | multiple interactions | ISO | LRATD1 (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in decreased methylation of LRATD1 gene | CTD | PMID:31601247 | Lratd1 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of LRATD1 mRNA | CTD | PMID:27387713 | Lratd1 | Rat | genistein | increases expression | ISO | Lratd1 (Mus musculus) | 6480464 | Genistein results in increased expression of LRATD1 mRNA | CTD | PMID:32186404 | Lratd1 | Rat | glycine betaine | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B more ... | CTD | PMID:33549593 | Lratd1 | Rat | gold atom | increases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | Gold results in increased expression of LRATD1 mRNA | CTD | PMID:25523186 | Lratd1 | Rat | gold(0) | increases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | Gold results in increased expression of LRATD1 mRNA | CTD | PMID:25523186 | Lratd1 | Rat | indometacin | multiple interactions | ISO | LRATD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Lratd1 | Rat | L-methionine | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B more ... | CTD | PMID:33549593 | Lratd1 | Rat | methamphetamine | affects expression | EXP | | 6480464 | Methamphetamine affects the expression of LRATD1 mRNA | CTD | PMID:19564919 | Lratd1 | Rat | methylmercury chloride | decreases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of LRATD1 mRNA | CTD | PMID:28001369 | Lratd1 | Rat | ochratoxin A | decreases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | ochratoxin A results in decreased expression of LRATD1 mRNA | CTD | PMID:22124623 | Lratd1 | Rat | paracetamol | affects expression | ISO | Lratd1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of LRATD1 mRNA | CTD | PMID:17562736 | Lratd1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of FAM84A mRNA | CTD | PMID:33387578 | Lratd1 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of FAM84A mRNA | CTD | PMID:35163327 | Lratd1 | Rat | phenobarbital | increases expression | ISO | Lratd1 (Mus musculus) | 6480464 | Phenobarbital results in increased expression of LRATD1 mRNA; Phenobarbital results in increased expression of LRATD1 more ... | CTD | PMID:19482888|PMID:21424122|PMID:23091169|PMID:33549593 | Lratd1 | Rat | phenobarbital | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B more ... | CTD | PMID:19482888|PMID:21424122|PMID:33549593 | Lratd1 | Rat | phenylmercury acetate | multiple interactions | ISO | LRATD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Lratd1 | Rat | pirinixic acid | decreases expression | ISO | Lratd1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of LRATD1 mRNA | CTD | PMID:17426115|PMID:20813756 | Lratd1 | Rat | pirinixic acid | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Lratd1 | Rat | propanal | increases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of LRATD1 mRNA | CTD | PMID:26079696 | Lratd1 | Rat | propiconazole | increases expression | ISO | Lratd1 (Mus musculus) | 6480464 | propiconazole results in increased expression of LRATD1 mRNA | CTD | PMID:21278054 | Lratd1 | Rat | resveratrol | multiple interactions | ISO | LRATD1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of LRATD1 mRNA | CTD | PMID:23557933 | Lratd1 | Rat | rotenone | increases expression | ISO | Lratd1 (Mus musculus) | 6480464 | Rotenone results in increased expression of FAM84A mRNA | CTD | PMID:32937126 | Lratd1 | Rat | S-nitrosoglutathione | increases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | S-Nitrosoglutathione results in increased expression of LRATD1 mRNA | CTD | PMID:38825487 | Lratd1 | Rat | SB 431542 | multiple interactions | ISO | LRATD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Lratd1 | Rat | silicon dioxide | increases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of LRATD1 mRNA | CTD | PMID:23806026|PMID:25895662 | Lratd1 | Rat | sodium arsenite | decreases expression | ISO | Lratd1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of LRATD1 mRNA | CTD | PMID:37682722 | Lratd1 | Rat | tetraphene | decreases expression | ISO | Lratd1 (Mus musculus) | 6480464 | benz(a)anthracene results in decreased expression of LRATD1 mRNA | CTD | PMID:26377693 | Lratd1 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of LRATD1 mRNA | CTD | PMID:34492290 | Lratd1 | Rat | titanium dioxide | decreases expression | ISO | Lratd1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of FAM84A mRNA; titanium dioxide results in decreased expression more ... | CTD | PMID:23557971|PMID:29264374 | Lratd1 | Rat | titanium dioxide | decreases methylation | ISO | Lratd1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of FAM84A gene | CTD | PMID:35295148 | Lratd1 | Rat | trichostatin A | decreases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of LRATD1 mRNA | CTD | PMID:24935251 | Lratd1 | Rat | triclosan | increases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | Triclosan results in increased expression of LRATD1 mRNA | CTD | PMID:30510588 | Lratd1 | Rat | valproic acid | increases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of LRATD1 mRNA | CTD | PMID:19101580|PMID:23179753|PMID:27188386 | Lratd1 | Rat | valproic acid | decreases expression | ISO | LRATD1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of LRATD1 mRNA | CTD | PMID:28001369 | Lratd1 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of LRATD1 mRNA | CTD | PMID:20566332 | Lratd1 | Rat | zinc atom | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B more ... | CTD | PMID:33549593 | Lratd1 | Rat | zinc(0) | multiple interactions | ISO | Lratd1 (Mus musculus) | 6480464 | [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B more ... | CTD | PMID:33549593 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















