Mcm3 (minichromosome maintenance complex component 3) - Rat Genome Database

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Gene: Mcm3 (minichromosome maintenance complex component 3) Rattus norvegicus
Analyze
Symbol: Mcm3
Name: minichromosome maintenance complex component 3
RGD ID: 1305168
Description: Predicted to enable single-stranded DNA binding activity. Predicted to contribute to single-stranded DNA helicase activity. Predicted to be involved in DNA strand elongation involved in DNA replication; double-strand break repair via break-induced replication; and mitotic DNA replication initiation. Predicted to be located in perinuclear region of cytoplasm. Predicted to be part of CMG complex and MCM complex. Predicted to be active in nucleus. Orthologous to human MCM3 (minichromosome maintenance complex component 3); PARTICIPATES IN cell cycle pathway, mitotic; DNA replication pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DNA replication licensing factor MCM3; LOC316273; minichromosome maintenance deficient 3; minichromosome maintenance deficient 3 (S. cerevisiae)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8930,715,602 - 30,733,746 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl930,715,602 - 30,733,746 (-)EnsemblGRCr8
mRatBN7.2923,219,169 - 23,237,314 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl923,219,169 - 23,237,314 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx931,708,279 - 31,726,367 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0936,828,996 - 36,847,084 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0935,144,261 - 35,162,350 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0926,914,057 - 26,932,201 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl926,914,057 - 26,932,201 (-)Ensemblrn6Rnor6.0
Rnor_5.0925,770,288 - 25,788,432 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4919,536,922 - 19,554,871 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera920,794,785 - 20,812,805 (-)NCBICelera
RGSC_v3.1919,534,642 - 19,552,122 (-)NCBI
Cytogenetic Map9q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-dioxane  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (EXP)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,2'-Methylenebis(4-methyl-6-tert-butylphenol)  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-diaminotoluene  (ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-methylcholanthrene  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nitrophenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-amanitin  (ISO)
AM-251  (ISO)
aminoglutethimide  (ISO)
amphetamine  (EXP)
anthracene-1,8,9-triol  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
auraptene  (ISO)
azathioprine  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
CGP 52608  (ISO)
chlorpromazine  (ISO)
cholic acid  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
corticosterone  (EXP)
coumarin  (EXP)
coumestrol  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
diminazene diaceturate  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
Evodiamine  (ISO)
FR900359  (ISO)
furan  (EXP)
glycine betaine  (EXP)
glyphosate  (ISO)
GW 3965  (ISO)
hydrogen peroxide  (ISO)
iron dichloride  (ISO)
iron trichloride  (ISO)
iron(III) nitrilotriacetate  (EXP)
ivermectin  (ISO)
ketamine  (EXP)
lead(0)  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
methylseleninic acid  (ISO)
Mezerein  (ISO)
miconazole  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monoethyl phthalate  (ISO)
N-(6-acetamidohexyl)acetamide  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
nitrates  (ISO)
Nonylphenol  (ISO)
ochratoxin A  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
palytoxin  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
PCB138  (ISO)
pentachlorophenol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
saccharin  (ISO)
SB 431542  (ISO)
senecionine  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
silver(1+) nitrate  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
sodium nitrite  (ISO)
styrene oxide  (ISO)
sulfadimethoxine  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
toluene 2,4-diisocyanate  (ISO)
topotecan  (EXP)
Tributyltin oxide  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromosome  (IEA)
cytoplasm  (IEA,ISO)
MCM complex  (IBA,IEA,ISO)
nucleolus  (ISO)
nucleus  (IBA,IEA,ISO)
perinuclear region of cytoplasm  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17296731   PMID:18590716   PMID:19135898   PMID:19946888   PMID:20531406   PMID:21383955   PMID:22082260   PMID:25002582   PMID:30361391   PMID:31505169  


Genomics

Comparative Map Data
Mcm3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8930,715,602 - 30,733,746 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl930,715,602 - 30,733,746 (-)EnsemblGRCr8
mRatBN7.2923,219,169 - 23,237,314 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl923,219,169 - 23,237,314 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx931,708,279 - 31,726,367 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0936,828,996 - 36,847,084 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0935,144,261 - 35,162,350 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0926,914,057 - 26,932,201 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl926,914,057 - 26,932,201 (-)Ensemblrn6Rnor6.0
Rnor_5.0925,770,288 - 25,788,432 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4919,536,922 - 19,554,871 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera920,794,785 - 20,812,805 (-)NCBICelera
RGSC_v3.1919,534,642 - 19,552,122 (-)NCBI
Cytogenetic Map9q13NCBI
MCM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38652,264,015 - 52,284,742 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl652,264,011 - 52,284,881 (-)Ensemblhg38GRCh38
GRCh37652,128,813 - 52,149,540 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36652,236,771 - 52,257,541 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34652,236,770 - 52,257,541NCBI
Celera653,789,937 - 53,810,711 (-)NCBICelera
Cytogenetic Map6p12.2NCBI
HuRef651,960,041 - 51,980,910 (-)NCBIHuRef
CHM1_1652,131,052 - 52,151,919 (-)NCBICHM1_1
T2T-CHM13v2.0652,102,764 - 52,123,487 (-)NCBIT2T-CHM13v2.0
Mcm3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39120,873,188 - 20,890,536 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl120,873,192 - 20,890,536 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38120,802,966 - 20,820,312 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl120,802,968 - 20,820,312 (-)Ensemblmm10GRCm38
MGSCv37120,793,095 - 20,810,294 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36120,788,165 - 20,805,364 (-)NCBIMGSCv36mm8
Celera120,676,980 - 20,695,949 (-)NCBICelera
Cytogenetic Map1A4NCBI
cM Map16.5NCBI
Mcm3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554115,814,041 - 5,832,796 (+)Ensembl
ChiLan1.0NW_0049554115,800,800 - 5,832,713 (+)NCBIChiLan1.0ChiLan1.0
MCM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2566,732,230 - 66,754,058 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1662,609,065 - 62,629,834 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0651,816,615 - 51,837,404 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1653,084,657 - 53,105,403 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl653,085,231 - 53,105,344 (-)EnsemblpanPan2panpan1.1
MCM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11219,924,017 - 19,945,576 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1219,920,210 - 19,945,605 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1219,821,166 - 19,842,529 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01220,422,999 - 20,444,648 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1220,422,997 - 20,444,648 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11219,928,809 - 19,950,166 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01220,031,993 - 20,053,341 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01220,170,450 - 20,191,818 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mcm3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494655,412,234 - 55,429,506 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364768,530,688 - 8,547,978 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364768,530,614 - 8,547,971 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl746,084,662 - 46,104,375 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1746,084,648 - 46,104,425 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2752,534,805 - 52,554,554 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MCM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11720,222,440 - 20,243,807 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1720,222,590 - 20,243,809 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604452,162,228 - 52,183,499 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mcm3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248553,806,553 - 3,827,873 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248553,806,273 - 3,825,143 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Mcm3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1498,172,509 - 98,190,605 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mcm3
215 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:49
Count of miRNA genes:47
Interacting mature miRNAs:47
Transcripts:ENSRNOT00000017081
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9534647950346479Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9875049253750492Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)92956766474567664Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)9131250552Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)949664545496645Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9621499551214995Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9875049253750492Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9141763315Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9534647950416711Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)949664545496645Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)92103143049025574Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)949664545496645Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9621499551214995Rat

Markers in Region
RH141374  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2923,219,253 - 23,219,433 (+)MAPPERmRatBN7.2
Rnor_6.0926,914,142 - 26,914,321NCBIRnor6.0
Rnor_5.0925,770,373 - 25,770,552UniSTSRnor5.0
RGSC_v3.4919,537,007 - 19,537,186UniSTSRGSC3.4
Celera920,794,870 - 20,795,049UniSTS
RH 3.4 Map9229.1UniSTS
Cytogenetic Map9q13UniSTS
MARC_3939-3940:996679197:3  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8930,730,987 - 30,731,598 (+)Marker Load Pipeline
mRatBN7.2923,234,555 - 23,235,166 (+)MAPPERmRatBN7.2
Rnor_6.0926,929,443 - 26,930,053NCBIRnor6.0
Rnor_5.0925,785,674 - 25,786,284UniSTSRnor5.0
RGSC_v3.4919,552,130 - 19,552,740UniSTSRGSC3.4
Celera920,810,047 - 20,810,657UniSTS
Cytogenetic Map9q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001191805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000017081   ⟹   ENSRNOP00000017081
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl930,715,602 - 30,733,746 (-)Ensembl
mRatBN7.2 Ensembl923,219,169 - 23,237,314 (-)Ensembl
Rnor_6.0 Ensembl926,914,057 - 26,932,201 (-)Ensembl
RefSeq Acc Id: NM_001191805   ⟹   NP_001178734
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8930,715,602 - 30,733,746 (-)NCBI
mRatBN7.2923,219,169 - 23,237,314 (-)NCBI
Rnor_6.0926,914,057 - 26,932,201 (-)NCBI
Rnor_5.0925,770,288 - 25,788,432 (-)NCBI
Celera920,794,785 - 20,812,805 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001178734 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017081
  ENSRNOP00000017081.7
RefSeq Acc Id: NP_001178734   ⟸   NM_001191805
- UniProtKB: D3ZFP4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017081   ⟸   ENSRNOT00000017081
Protein Domains
MCM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZFP4-F1-model_v2 AlphaFold D3ZFP4 1-813 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696572
Promoter ID:EPDNEW_R7097
Type:initiation region
Name:Mcm3_1
Description:minichromosome maintenance complex component 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0926,932,148 - 26,932,208EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305168 AgrOrtholog
BioCyc Gene G2FUF-28030 BioCyc
Ensembl Genes ENSRNOG00000012543 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017081 ENTREZGENE
  ENSRNOT00000017081.9 UniProtKB/TrEMBL
Gene3D-CATH 2.20.28.10 UniProtKB/TrEMBL
  2.40.50.140 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  mini-chromosome maintenance (MCM) complex, chain A, domain 1 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  DNA-dep_ATPase_MCM UniProtKB/TrEMBL
  DNA-dep_ATPase_MCM_CS UniProtKB/TrEMBL
  MCM UniProtKB/TrEMBL
  MCM_3 UniProtKB/TrEMBL
  MCM_lid UniProtKB/TrEMBL
  MCM_N UniProtKB/TrEMBL
  MCM_OB UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  WH_MCM3_C UniProtKB/TrEMBL
KEGG Report rno:316273 UniProtKB/TrEMBL
NCBI Gene 316273 ENTREZGENE
PANTHER DNA REPLICATION LICENSING FACTOR MCM3 UniProtKB/TrEMBL
  PTHR11630 UniProtKB/TrEMBL
Pfam MCM UniProtKB/TrEMBL
  MCM_lid UniProtKB/TrEMBL
  MCM_N UniProtKB/TrEMBL
  MCM_OB UniProtKB/TrEMBL
  WH_MCM3_C UniProtKB/TrEMBL
PhenoGen Mcm3 PhenoGen
PRINTS MCMFAMILY UniProtKB/TrEMBL
  MCMPROTEIN3 UniProtKB/TrEMBL
PROSITE MCM_1 UniProtKB/TrEMBL
  MCM_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012543 RatGTEx
SMART AAA UniProtKB/TrEMBL
  MCM UniProtKB/TrEMBL
Superfamily-SCOP Nucleic_acid_OB UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt D3ZFP4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-24 Mcm3  minichromosome maintenance complex component 3  Mcm3  minichromosome maintenance deficient 3 (S. cerevisiae)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Mcm3  minichromosome maintenance deficient 3 (S. cerevisiae)   Mcm3_predicted  minichromosome maintenance deficient 3 (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Mcm3_predicted  minichromosome maintenance deficient 3 (S. cerevisiae) (predicted)      Symbol and Name status set to approved 70820 APPROVED