Epha6 (Eph receptor A6) - Rat Genome Database

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Gene: Epha6 (Eph receptor A6) Rattus norvegicus
Analyze
Symbol: Epha6
Name: Eph receptor A6
RGD ID: 1304614
Description: Predicted to enable transmembrane-ephrin receptor activity. Predicted to be involved in axon guidance and ephrin receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in dendrite and plasma membrane. Orthologous to human EPHA6 (EPH receptor A6); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 6-propyl-2-thiouracil; allethrin; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AABR07033882.1; EHK-2; Ehk2; EPH homology kinase 2; ephrin type-A receptor 6; tyrosine-protein kinase receptor EHK-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81153,226,784 - 54,178,120 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1153,226,954 - 54,166,987 (+)EnsemblGRCr8
mRatBN7.21139,757,501 - 40,708,901 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1139,757,181 - 40,698,311 (+)EnsemblmRatBN7.2
Rnor_6.01141,867,607 - 42,843,800 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1142,259,761 - 42,843,865 (+)NCBIrn6Rnor6.0
Rnor_5.01145,066,461 - 46,035,688 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41140,551,554 - 41,458,539 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1139,606,772 - 40,545,970 (+)NCBICelera
RGSC_v3.11140,597,889 - 41,024,933 (+)NCBI
Cytogenetic Map11q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
dendrite  (IBA)
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7504232   PMID:15057822  


Genomics

Comparative Map Data
Epha6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81153,226,784 - 54,178,120 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1153,226,954 - 54,166,987 (+)EnsemblGRCr8
mRatBN7.21139,757,501 - 40,708,901 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1139,757,181 - 40,698,311 (+)EnsemblmRatBN7.2
Rnor_6.01141,867,607 - 42,843,800 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1142,259,761 - 42,843,865 (+)NCBIrn6Rnor6.0
Rnor_5.01145,066,461 - 46,035,688 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41140,551,554 - 41,458,539 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1139,606,772 - 40,545,970 (+)NCBICelera
RGSC_v3.11140,597,889 - 41,024,933 (+)NCBI
Cytogenetic Map11q12NCBI
EPHA6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38396,814,594 - 97,761,532 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl396,814,581 - 97,761,532 (+)Ensemblhg38GRCh38
GRCh37396,533,438 - 97,480,376 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36398,016,115 - 98,950,476 (+)NCBIBuild 36Build 36hg18NCBI36
Celera394,916,109 - 95,857,365 (+)NCBICelera
Cytogenetic Map3q11.2NCBI
HuRef393,902,924 - 94,837,692 (+)NCBIHuRef
CHM1_1396,496,480 - 97,430,819 (+)NCBICHM1_1
T2T-CHM13v2.0399,518,416 - 100,468,755 (+)NCBIT2T-CHM13v2.0
Epha6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391659,473,424 - 60,431,196 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1659,473,846 - 60,425,894 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381659,641,433 - 60,610,911 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1659,653,483 - 60,605,531 (-)Ensemblmm10GRCm38
MGSCv371659,653,309 - 60,605,357 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361659,595,739 - 60,547,503 (-)NCBIMGSCv36mm8
Celera1660,004,715 - 60,923,397 (-)NCBICelera
Cytogenetic Map16C1.3NCBI
cM Map1634.83NCBI
Epha6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955407400,745 - 1,220,538 (-)Ensembl
ChiLan1.0NW_004955407398,415 - 1,220,542 (-)NCBIChiLan1.0ChiLan1.0
EPHA6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2294,719,146 - 95,674,832 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1394,723,932 - 95,679,616 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0393,881,686 - 94,819,563 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13100,562,841 - 101,504,222 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3100,734,791 - 101,503,805 (+)EnsemblpanPan2panpan1.1
EPHA6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1333,990,346 - 4,786,070 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl334,517,039 - 4,684,336 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha334,093,700 - 4,967,547 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0334,023,454 - 4,896,341 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.1333,901,331 - 4,772,858 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0333,961,065 - 4,833,214 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0334,235,497 - 5,107,565 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Epha6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602152,451,572 - 153,234,891 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366662,282,000 - 3,061,944 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366662,280,811 - 3,063,601 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPHA6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13162,569,479 - 163,443,646 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113162,568,835 - 163,445,722 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213173,570,910 - 173,735,724 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPHA6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12282,960,714 - 83,914,993 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604182,679,583 - 83,623,162 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Epha6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247899,281,370 - 10,209,495 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247899,279,440 - 10,211,840 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Epha6
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1443,482,068 - 44,375,741 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Epha6
5047 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:93
Count of miRNA genes:74
Interacting mature miRNAs:76
Transcripts:ENSRNOT00000047310
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
11528648Bss118Bone structure and strength QTL 1186.6582e-07femur strength trait (VT:0010010)femur ultimate displacement (CMO:0002719)115410798756845449Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)111080612555806125Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)113532319955805892Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)112995899657754989Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)112631803155806125Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat

Markers in Region
D11Rat85  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21140,304,169 - 40,304,418 (+)MAPPERmRatBN7.2
Rnor_6.01142,434,750 - 42,434,998NCBIRnor6.0
Rnor_5.01145,623,663 - 45,623,911UniSTSRnor5.0
RGSC_v3.41141,127,119 - 41,127,368RGDRGSC3.4
RGSC_v3.41141,127,120 - 41,127,368UniSTSRGSC3.4
Celera1140,147,720 - 40,147,968UniSTS
RGSC_v3.11141,184,708 - 41,184,957RGD
FHH x ACI Map1116.5799RGD
FHH x ACI Map1116.5799UniSTS
Cytogenetic Map11q12UniSTS
D11Got84  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21140,637,916 - 40,638,019 (+)MAPPERmRatBN7.2
Rnor_6.01142,783,879 - 42,783,981NCBIRnor6.0
Rnor_5.01145,974,373 - 45,974,475UniSTSRnor5.0
RGSC_v3.41141,399,190 - 41,399,293RGDRGSC3.4
RGSC_v3.41141,399,191 - 41,399,293UniSTSRGSC3.4
Celera1140,479,883 - 40,479,985UniSTS
RGSC_v3.11141,456,780 - 41,456,882RGD
RH 3.4 Map11295.5UniSTS
RH 3.4 Map11295.5RGD
RH 2.0 Map11315.1RGD
Cytogenetic Map11q12UniSTS
RH144116  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21140,697,347 - 40,697,570 (+)MAPPERmRatBN7.2
Rnor_6.01142,843,946 - 42,844,168NCBIRnor6.0
Rnor_5.01146,034,440 - 46,034,662UniSTSRnor5.0
RGSC_v3.41141,458,620 - 41,458,842UniSTSRGSC3.4
Celera1140,539,323 - 40,539,545UniSTS
RH 3.4 Map11292.6UniSTS
Cytogenetic Map11q12UniSTS
BF415441  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81153,446,025 - 53,446,139 (+)Marker Load Pipeline
mRatBN7.21139,976,760 - 39,976,874 (+)MAPPERmRatBN7.2
Rnor_6.01142,104,992 - 42,105,105NCBIRnor6.0
Rnor_5.01145,302,005 - 45,302,118UniSTSRnor5.0
RGSC_v3.41140,770,869 - 40,770,982UniSTSRGSC3.4
Celera1139,827,166 - 39,827,279UniSTS
RH 3.4 Map11293.4UniSTS
Cytogenetic Map11q12UniSTS
RH144183  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21139,755,746 - 39,756,006 (+)MAPPERmRatBN7.2
Rnor_6.01141,866,965 - 41,867,224NCBIRnor6.0
Rnor_5.01145,065,856 - 45,066,115UniSTSRnor5.0
RGSC_v3.41140,549,431 - 40,549,690UniSTSRGSC3.4
Celera1139,606,130 - 39,606,389UniSTS
RH 3.4 Map11292.7UniSTS
Cytogenetic Map11q12UniSTS
AU049238  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21140,133,726 - 40,133,900 (+)MAPPERmRatBN7.2
Rnor_6.01142,258,777 - 42,258,950NCBIRnor6.0
Rnor_5.01145,454,287 - 45,454,460UniSTSRnor5.0
RGSC_v3.41140,953,141 - 40,953,314UniSTSRGSC3.4
Celera1139,977,135 - 39,977,308UniSTS
Cytogenetic Map11q12UniSTS
mMECIR525  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21140,691,193 - 40,692,710 (+)MAPPERmRatBN7.2
Rnor_6.01142,837,784 - 42,839,300NCBIRnor6.0
Rnor_5.01146,028,278 - 46,029,794UniSTSRnor5.0
Celera1140,533,155 - 40,534,669UniSTS
Cytogenetic Map11q12UniSTS


Expression

RNA-SEQ Expression

circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
1 24 5 24 8 2 24 16 3 15 15

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001419529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000047310   ⟹   ENSRNOP00000049409
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1153,287,223 - 54,166,987 (+)Ensembl
mRatBN7.2 Ensembl1139,792,624 - 40,698,311 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097751   ⟹   ENSRNOP00000087819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1153,226,954 - 54,166,987 (+)Ensembl
mRatBN7.2 Ensembl1139,757,181 - 40,698,311 (+)Ensembl
RefSeq Acc Id: NM_001419529   ⟹   NP_001406458
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81153,226,784 - 54,178,120 (+)NCBI
mRatBN7.21139,757,501 - 40,708,901 (+)NCBI
RefSeq Acc Id: XM_039088720   ⟹   XP_038944648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81153,261,732 - 54,178,120 (+)NCBI
mRatBN7.21139,792,037 - 40,708,901 (+)NCBI
RefSeq Acc Id: XM_039088721   ⟹   XP_038944649
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81153,261,733 - 54,178,120 (+)NCBI
mRatBN7.21139,792,040 - 40,708,901 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001406458 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944648 (Get FASTA)   NCBI Sequence Viewer  
  XP_038944649 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000049409
  ENSRNOP00000087819
GenBank Protein P54758 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_038944648   ⟸   XM_039088720
- Peptide Label: isoform X1
- UniProtKB: P54758 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038944649   ⟸   XM_039088721
- Peptide Label: isoform X2
- UniProtKB: P54758 (UniProtKB/Swiss-Prot),   F1LQK6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000087819   ⟸   ENSRNOT00000097751
Ensembl Acc Id: ENSRNOP00000049409   ⟸   ENSRNOT00000047310
RefSeq Acc Id: NP_001406458   ⟸   NM_001419529
- UniProtKB: P54758 (UniProtKB/Swiss-Prot),   A0A8I6A6J8 (UniProtKB/TrEMBL)
Protein Domains
Eph LBD   Fibronectin type-III   Protein kinase   SAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P54758-F1-model_v2 AlphaFold P54758 1-1035 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304614 AgrOrtholog
BioCyc Gene G2FUF-21631 BioCyc
Ensembl Genes ENSRNOG00000029184 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000047310 ENTREZGENE
  ENSRNOT00000097751 ENTREZGENE
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot
  2.60.40.10 UniProtKB/Swiss-Prot
  ephrin a2 ectodomain UniProtKB/Swiss-Prot
  Galactose-binding domain-like UniProtKB/Swiss-Prot
  Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
  Tumor Necrosis Factor Receptor, subunit A, domain 2 UniProtKB/Swiss-Prot
InterPro EPH-A6_SAM UniProtKB/Swiss-Prot
  Eph_TM UniProtKB/Swiss-Prot
  EphA6_rcpt_lig-bd UniProtKB/Swiss-Prot
  Ephrin_rcpt_lig-bd_dom UniProtKB/Swiss-Prot
  Ephrin_rcpt_TKs UniProtKB/Swiss-Prot
  FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  Galactose-bd-like_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
  SAM/pointed_sf UniProtKB/Swiss-Prot
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
  Tyr-kin_ephrin_A/B_rcpt-like UniProtKB/Swiss-Prot
  Tyr_kinase_AS UniProtKB/Swiss-Prot
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
  Tyr_kinase_ephrin_rcpt UniProtKB/Swiss-Prot
  Tyr_kinase_rcpt_V_CS UniProtKB/Swiss-Prot
NCBI Gene 29202 ENTREZGENE
PANTHER EPH RECEPTOR A5 UniProtKB/Swiss-Prot
  EPHRIN TYPE-A RECEPTOR 6 UniProtKB/Swiss-Prot
Pfam EphA2_TM UniProtKB/Swiss-Prot
  Ephrin_lbd UniProtKB/Swiss-Prot
  Ephrin_rec_like UniProtKB/Swiss-Prot
  fn3 UniProtKB/Swiss-Prot
  Pkinase_Tyr UniProtKB/Swiss-Prot
  SAM_1 UniProtKB/Swiss-Prot
PhenoGen Epha6 PhenoGen
PIRSF TyrPK_ephrin_receptor UniProtKB/Swiss-Prot
PRINTS FNTYPEIII UniProtKB/Swiss-Prot
  TYRKINASE UniProtKB/Swiss-Prot
PROSITE EGF_2 UniProtKB/Swiss-Prot
  EPH_LBD UniProtKB/Swiss-Prot
  FN3 UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot
  RECEPTOR_TYR_KIN_V_1 UniProtKB/Swiss-Prot
  RECEPTOR_TYR_KIN_V_2 UniProtKB/Swiss-Prot
  SAM_DOMAIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000029184 RatGTEx
SMART EPH_lbd UniProtKB/Swiss-Prot
  Ephrin_rec_like UniProtKB/Swiss-Prot
  FN3 UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
  TyrKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47769 UniProtKB/Swiss-Prot
  SSF49265 UniProtKB/Swiss-Prot
  SSF49785 UniProtKB/Swiss-Prot
  SSF56112 UniProtKB/Swiss-Prot
UniProt A0A8I6A6J8 ENTREZGENE, UniProtKB/TrEMBL
  EPHA6_RAT UniProtKB/Swiss-Prot
  F1LQK6 ENTREZGENE, UniProtKB/TrEMBL
  P54758 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Epha6  Eph receptor A6  AABR07033882.1    Data merged from RGD:15003733 737654 PROVISIONAL
2021-09-02 AABR07033882.1    Epha6  Eph receptor A6  Symbol and/or name change 19259462 PROVISIONAL
2021-08-09 Epha6  Eph receptor A6  AABR07033882.1    Symbol and/or name change 19259462 PROVISIONAL
2019-11-08 AABR07033882.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2008-04-30 Epha6  Eph receptor A6   Epha6_predicted  Eph receptor A6 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Epha6_predicted  Eph receptor A6 (predicted)      Symbol and Name status set to approved 70820 APPROVED