Nfkbil1 (NFKB inhibitor like 1) - Rat Genome Database

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Pathways
Gene: Nfkbil1 (NFKB inhibitor like 1) Rattus norvegicus
Analyze
Symbol: Nfkbil1
Name: NFKB inhibitor like 1
RGD ID: 1303310
Description: Predicted to enable transcription regulator inhibitor activity. Predicted to be involved in cellular response to lipopolysaccharide; negative regulation of signal transduction; and regulation of gene expression. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human NFKBIL1 (NFKB inhibitor like 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: I-kappa-B-like protein; ikappaBL; IkBL; inhibitor of kappa B-like protein; NF-kappa-B inhibitor-like protein 1; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1; putative inhibitor of Rel family transcription factors
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,595,319 - 3,610,295 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl203,595,284 - 3,610,294 (+)EnsemblGRCr8
mRatBN7.2203,589,974 - 3,608,348 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,590,642 - 3,605,616 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx204,290,621 - 4,305,605 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0203,652,685 - 3,667,669 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,190,181 - 4,205,242 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,823,590 - 4,839,202 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,822,935 - 4,839,202 (+)Ensemblrn6Rnor6.0
Rnor_5.0206,903,968 - 6,919,602 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4203,629,246 - 3,644,222 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera204,419,824 - 4,434,802 (-)NCBICelera
RGSC_v3.1203,629,467 - 3,644,449 (+)NCBI
Cytogenetic Map20p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Identification of I kappa BL as the second major histocompatibility complex-linked susceptibility locus for rheumatoid arthritis. Okamoto K, etal., Am J Hum Genet 2003 Feb;72(2):303-12. Epub 2002 Dec 31.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11904681   PMID:12477932   PMID:15060004   PMID:20829348   PMID:22024480  


Genomics

Comparative Map Data
Nfkbil1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,595,319 - 3,610,295 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl203,595,284 - 3,610,294 (+)EnsemblGRCr8
mRatBN7.2203,589,974 - 3,608,348 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,590,642 - 3,605,616 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx204,290,621 - 4,305,605 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0203,652,685 - 3,667,669 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,190,181 - 4,205,242 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0204,823,590 - 4,839,202 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,822,935 - 4,839,202 (+)Ensemblrn6Rnor6.0
Rnor_5.0206,903,968 - 6,919,602 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4203,629,246 - 3,644,222 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera204,419,824 - 4,434,802 (-)NCBICelera
RGSC_v3.1203,629,467 - 3,644,449 (+)NCBI
Cytogenetic Map20p12NCBI
NFKBIL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,546,851 - 31,558,829 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl631,546,870 - 31,558,829 (+)Ensemblhg38GRCh38
GRCh37631,514,628 - 31,526,606 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,623,351 - 31,634,585 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34631,623,350 - 31,634,584NCBI
Celera633,112,858 - 33,124,825 (+)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,301,366 - 31,313,342 (+)NCBIHuRef
CHM1_1631,516,762 - 31,528,738 (+)NCBICHM1_1
T2T-CHM13v2.0631,399,939 - 31,411,908 (+)NCBIT2T-CHM13v2.0
Nfkbil1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,439,151 - 35,455,457 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,439,151 - 35,454,768 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381735,220,175 - 35,236,481 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,220,175 - 35,235,792 (-)Ensemblmm10GRCm38
MGSCv371735,357,120 - 35,372,760 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361734,828,227 - 34,843,867 (-)NCBIMGSCv36mm8
Celera1738,316,892 - 38,337,965 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.6NCBI
Nfkbil1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543790,577 - 100,918 (+)Ensembl
ChiLan1.0NW_00495543790,623 - 100,918 (+)NCBIChiLan1.0ChiLan1.0
NFKBIL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,023,790 - 46,041,258 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1641,985,346 - 41,997,336 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,207,927 - 31,219,916 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,097,824 - 32,109,944 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,098,554 - 32,109,944 (+)EnsemblpanPan2panpan1.1
NFKBIL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,048,393 - 1,057,458 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,049,109 - 1,057,237 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha121,185,620 - 1,193,682 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0121,193,625 - 1,202,695 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,194,366 - 1,202,692 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,053,212 - 1,061,226 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,121,119 - 1,129,138 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,187,867 - 1,195,929 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nfkbil1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,597,631 - 35,611,277 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,950,057 - 1,963,245 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,950,356 - 1,963,847 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NFKBIL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,673,297 - 23,685,088 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1723,673,002 - 23,685,089 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,566,956 - 27,578,752 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NFKBIL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11740,428,001 - 40,440,386 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1740,428,222 - 40,439,433 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604431,447,986 - 31,460,396 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nfkbil1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,639,860 - 24,649,968 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475424,639,757 - 24,652,059 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Nfkbil1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1187,815,339 - 7,836,190 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nfkbil1
259 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:140
Count of miRNA genes:103
Interacting mature miRNAs:116
Transcripts:ENSRNOT00000001113
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015332005306452Rat
61474Eae1Experimental allergic encephalomyelitis QTL 13nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)2016693431Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126128279Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)2016693431Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013629303Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20114100378Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat

Markers in Region
AA997909  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,605,451 - 3,605,583 (+)MAPPERmRatBN7.2
Rnor_6.0204,839,037 - 4,839,168NCBIRnor6.0
Rnor_5.0206,919,437 - 6,919,568UniSTSRnor5.0
RGSC_v3.4203,644,057 - 3,644,188UniSTSRGSC3.4
Celera204,419,858 - 4,419,989UniSTS
RH 3.4 Map2051.1UniSTS
Cytogenetic Map20p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000001113   ⟹   ENSRNOP00000001113
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,590,642 - 3,605,616 (+)Ensembl
Rnor_6.0 Ensembl204,824,226 - 4,839,202 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077200   ⟹   ENSRNOP00000070388
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl204,822,935 - 4,838,468 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000086673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl204,837,642 - 4,838,340 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090028   ⟹   ENSRNOP00000075421
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl204,823,662 - 4,838,412 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000120806   ⟹   ENSRNOP00000098419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl203,595,284 - 3,610,294 (+)Ensembl
RefSeq Acc Id: NM_212509   ⟹   NP_997674
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8203,595,319 - 3,610,295 (+)NCBI
mRatBN7.2203,590,642 - 3,605,617 (+)NCBI
Rnor_6.0204,824,226 - 4,839,202 (+)NCBI
Rnor_5.0206,903,968 - 6,919,602 (+)NCBI
RGSC_v3.4203,629,246 - 3,644,222 (+)RGD
Celera204,419,824 - 4,434,802 (-)RGD
Sequence:
RefSeq Acc Id: NP_997674   ⟸   NM_212509
- UniProtKB: Q499T4 (UniProtKB/Swiss-Prot),   Q8R2H1 (UniProtKB/Swiss-Prot),   A6KTX0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075421   ⟸   ENSRNOT00000090028
Ensembl Acc Id: ENSRNOP00000070388   ⟸   ENSRNOT00000077200
Ensembl Acc Id: ENSRNOP00000001113   ⟸   ENSRNOT00000001113
Ensembl Acc Id: ENSRNOP00000098419   ⟸   ENSRNOT00000120806

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8R2H1-F1-model_v2 AlphaFold Q8R2H1 1-381 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701366
Promoter ID:EPDNEW_R11890
Type:multiple initiation site
Name:Nfkbil1_1
Description:NFKB inhibitor like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0204,824,247 - 4,824,307EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303310 AgrOrtholog
BioCyc Gene G2FUF-4662 BioCyc
Ensembl Genes ENSRNOG00000000839 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000001113.6 UniProtKB/Swiss-Prot
  ENSRNOT00000120806 ENTREZGENE
Gene3D-CATH 1.25.40.20 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7932537 IMAGE-MGC_LOAD
InterPro Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot
  NFKBIL1 UniProtKB/Swiss-Prot
KEGG Report rno:361794 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124530 IMAGE-MGC_LOAD
NCBI Gene 361794 ENTREZGENE
PANTHER NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1 UniProtKB/Swiss-Prot
  PTHR15263 UniProtKB/Swiss-Prot
PhenoGen Nfkbil1 PhenoGen
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000000839 RatGTEx
Superfamily-SCOP SSF48403 UniProtKB/Swiss-Prot
UniProt A6KTX0 ENTREZGENE, UniProtKB/TrEMBL
  A6KTX1_RAT UniProtKB/TrEMBL
  IKBL1_RAT UniProtKB/Swiss-Prot
  Q499T4 ENTREZGENE
  Q811A8_RAT UniProtKB/TrEMBL
  Q8R2H1 ENTREZGENE
UniProt Secondary Q499T4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-01 Nfkbil1  NFKB inhibitor like 1  Nfkbil1  nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Nfkbil1  nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1      Symbol and Name status set to approved 1299863 APPROVED
2005-02-14 Nfkbil1  nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1      Symbol and Name status set to provisional 70820 PROVISIONAL