Rpl17 (ribosomal protein L17) - Rat Genome Database

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Gene: Rpl17 (ribosomal protein L17) Rattus norvegicus
Analyze
Symbol: Rpl17
Name: ribosomal protein L17
RGD ID: 1303019
Description: Enables large ribosomal subunit rRNA binding activity. Involved in cellular response to amino acid starvation and positive regulation of G1/S transition of mitotic cell cycle. Located in A band. Part of cytosolic large ribosomal subunit. Orthologous to human RPL17 (ribosomal protein L17); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 60S ribosomal protein L17; amino acid starvation-induced; ASI; L23; large ribosomal subunit protein uL22; MGC112577; rpL23
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: LOC121627837   Rpl17-ps1   Rpl17-ps11   Rpl17-ps16   Rpl17-ps17  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81870,856,275 - 70,859,388 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3111,722,010 - 111,722,638 (-)EnsemblGRCr8
GRCr8 Ensembl1870,856,294 - 70,859,385 (+)EnsemblGRCr8
mRatBN7.21868,581,141 - 68,584,253 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl391,267,220 - 91,267,774 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl1868,581,098 - 68,584,253 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1870,693,899 - 70,697,012 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01871,362,454 - 71,365,566 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01869,219,915 - 69,223,028 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01870,969,733 - 70,972,839 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1870,970,596 - 70,975,494 (+)Ensemblrn6Rnor6.0
Rnor_5.01870,108,978 - 70,112,084 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41871,863,062 - 71,866,168 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1866,756,106 - 66,759,212 (+)NCBICelera
RGSC_v3.11871,936,262 - 71,939,366 (+)NCBI
Cytogenetic Map18q12.2NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-bromohexadecanoic acid  (ISO)
2-nitrofluorene  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acrolein  (EXP,ISO)
aflatoxin B1  (EXP)
alpha-pinene  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
antimycin A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azoxystrobin  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chromium(6+)  (ISO)
clofibrate  (EXP)
copper(II) sulfate  (ISO)
deguelin  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenzo[a,l]pyrene  (ISO)
Dibutyl phosphate  (ISO)
diethylstilbestrol  (EXP)
diquat  (ISO)
disodium selenite  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fenpyroximate  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
hydralazine  (ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
ivermectin  (ISO)
L-ethionine  (EXP)
lead diacetate  (EXP)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
miconazole  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
nimesulide  (EXP)
omeprazole  (EXP)
ozone  (ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
picoxystrobin  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP)
pyrimidifen  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structures of the human and Drosophila 80S ribosome. Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
2. Carbodiimide-induced protein--RNA crosslinking in mammalian ribosomal subunits. Buisson M and Reboud AM, FEBS Lett. 1982 Nov 8;148(2):247-50.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Liver-specific induction of ribosomal protein gene expression by amino acid starvation in rats. Hitomi Y, etal., Biosci Biotechnol Biochem. 1993 Jul;57(7):1216-7.
6. Immunological localization of ribosomes in striated rat muscle. Evidence for myofibrillar association and ontological changes in the subsarcolemmal:myofibrillar distribution. Horne Z and Hesketh J, Biochem J. 1990 May 15;268(1):231-6.
7. Nuclear retention of the induced mRNA following amino acid-dependent transcriptional regulation of mammalian ribosomal proteins L17 and S25. Laine RO, etal., J Biol Chem 1994 Apr 1;269(13):9693-7.
8. Identification of an amino acid-regulated mRNA from rat liver as the mammalian equivalent of bacterial ribosomal protein L22. Laine RO, etal., J Biol Chem. 1991 Sep 15;266(26):16969-72.
9. GOA pipeline RGD automated data pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. Molecular cloning of an amino acid-regulated mRNA (amino acid starvation-induced) in rat hepatoma cells. Shay NF, etal., J Biol Chem 1990 Oct 15;265(29):17844-8.
13. Ribosomal protein L17, RpL17, is an inhibitor of vascular smooth muscle growth and carotid intima formation. Smolock EM, etal., Circulation. 2012 Nov 13;126(20):2418-27. doi: 10.1161/CIRCULATIONAHA.112.125971. Epub 2012 Oct 12.
Additional References at PubMed
PMID:2069571   PMID:12477932   PMID:12962325   PMID:16452087   PMID:16854843   PMID:21630459   PMID:22658674   PMID:22681889   PMID:30053369  


Genomics

Comparative Map Data
Rpl17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81870,856,275 - 70,859,388 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3111,722,010 - 111,722,638 (-)EnsemblGRCr8
GRCr8 Ensembl1870,856,294 - 70,859,385 (+)EnsemblGRCr8
mRatBN7.21868,581,141 - 68,584,253 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl391,267,220 - 91,267,774 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl1868,581,098 - 68,584,253 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1870,693,899 - 70,697,012 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01871,362,454 - 71,365,566 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01869,219,915 - 69,223,028 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01870,969,733 - 70,972,839 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1870,970,596 - 70,975,494 (+)Ensemblrn6Rnor6.0
Rnor_5.01870,108,978 - 70,112,084 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41871,863,062 - 71,866,168 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1866,756,106 - 66,759,212 (+)NCBICelera
RGSC_v3.11871,936,262 - 71,939,366 (+)NCBI
Cytogenetic Map18q12.2NCBI
RPL17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381849,488,481 - 49,492,465 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1849,488,346 - 49,492,564 (-)Ensemblhg38GRCh38
GRCh371847,014,851 - 47,018,835 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361845,268,852 - 45,272,904 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341845,268,855 - 45,272,849NCBI
Celera1843,870,209 - 43,874,262 (-)NCBICelera
Cytogenetic Map18q21.1NCBI
HuRef1843,868,521 - 43,872,605 (-)NCBIHuRef
CHM1_11847,010,161 - 47,014,245 (-)NCBICHM1_1
T2T-CHM13v2.01849,686,222 - 49,690,206 (-)NCBIT2T-CHM13v2.0
Rpl17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391875,132,049 - 75,136,455 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1875,131,629 - 75,136,452 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381874,998,978 - 75,003,381 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1874,998,558 - 75,003,381 (+)Ensemblmm10GRCm38
MGSCv371875,160,131 - 75,163,035 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361875,125,887 - 75,128,745 (+)NCBIMGSCv36mm8
Celera1876,224,173 - 76,227,059 (+)NCBICelera
Cytogenetic Map18E3NCBI
cM Map1850.96NCBI
RPL17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21767,016,409 - 67,021,957 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11852,708,881 - 52,714,560 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01842,870,133 - 42,874,162 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11846,219,527 - 46,223,586 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1846,219,530 - 46,223,503 (-)EnsemblpanPan2panpan1.1
LOC106559613
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11312,340,847 - 12,341,465 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1312,330,621 - 12,331,238 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01312,625,937 - 12,626,538 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11312,377,599 - 12,378,201 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01312,477,158 - 12,477,759 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01312,575,254 - 12,575,855 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rpl17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494438,218,242 - 38,222,227 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493649713,457,328 - 13,460,606 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPL17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl199,043,219 - 99,048,410 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1199,044,511 - 99,048,406 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21108,447,524 - 108,451,400 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RPL17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11831,473,050 - 31,477,287 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660505,693,487 - 5,697,782 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rpl17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477813,003,900 - 13,007,903 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477813,003,936 - 13,007,903 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Rpl17
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11556,980,554 - 56,983,676 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rpl17
11 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:23
Count of miRNA genes:20
Interacting mature miRNAs:23
Transcripts:ENSRNOT00000025217
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182507112683910656Rat
1331730Scl27Serum cholesterol level QTL 273.826blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)185449080186134022Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182349405785487725Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)186438376279484311Rat
631834Sach3Saccharin preference QTL 33.90.01consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)183857591983575919Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182682218671822186Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182682218671822186Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182682218671822186Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184562030686134022Rat
7794793Mcs34Mammary carcinoma susceptibility QTL 341.54mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)186563556785897775Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182682218671822186Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184891573786134022Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184891573786134022Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182682218671822186Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182682218671822186Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183199089176990891Rat
1331770Bp234Blood pressure QTL 2343.807arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184562030686134022Rat
2301969Bp324Blood pressure QTL 3244.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186198220476619168Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181206648285493247Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183161050585493247Rat
12880368Bw187Body weight QTL 1870.045body mass (VT:0001259)body weight (CMO:0000012)183337915878379158Rat
724542Kidm2Kidney mass QTL 22.6kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)186144685386134022Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)184046238385462383Rat
1359020Ppulsi2Prepulse inhibition QTL 22.71prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)185449080176272247Rat
2312600Bp341Blood pressure QTL 3410.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186160038472538878Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)183199089176990891Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181206648285493247Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181564228086134022Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)183337915878379158Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183161050577371277Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)183337915878379158Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)183337915878379158Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)185079521286134022Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182682218671822186Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183152278376522783Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)183337915878379158Rat
61384Bp48Blood pressure QTL 4819.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186289225779484461Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183337915878379158Rat
12904073Kidm71Kidney mass QTL 710.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)183337915878379158Rat
738008Hcar14Hepatocarcinoma resistance QTL 144.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion number (CMO:0001462)185782524385493247Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183161050577371277Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183612162681121626Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)183199089176990891Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184891573786134022Rat
631509Sald2Serum aldosterone level QTL 22.9blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)182641582171415821Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183164450879484311Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)186584644786134022Rat
1598832Glom11Glomerulus QTL 112.9kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)185326667186134022Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181955353285493247Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)183199089176990891Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)185079521286134022Rat
631675Iddm15Insulin dependent diabetes mellitus QTL 15urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)186289225779484461Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183161050572538878Rat

Markers in Region
BI286279  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21868,582,277 - 68,582,491 (+)MAPPERmRatBN7.2
Rnor_6.01870,970,864 - 70,971,077NCBIRnor6.0
Rnor_5.01870,110,109 - 70,110,322UniSTSRnor5.0
RGSC_v3.41871,864,193 - 71,864,406UniSTSRGSC3.4
Celera1866,757,237 - 66,757,450UniSTS
RH 3.4 Map18685.7UniSTS
Cytogenetic Map18q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_201415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039096639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC135265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC098644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M60478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X60212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000025217   ⟹   ENSRNOP00000025217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1870,856,294 - 70,859,385 (+)Ensembl
mRatBN7.2 Ensembl1868,581,098 - 68,584,253 (+)Ensembl
Rnor_6.0 Ensembl1870,970,596 - 70,972,821 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000039203   ⟹   ENSRNOP00000034364
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1870,970,596 - 70,975,494 (+)Ensembl
RefSeq Acc Id: NM_201415   ⟹   NP_958818
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,856,276 - 70,859,388 (+)NCBI
mRatBN7.21868,581,141 - 68,584,253 (+)NCBI
Rnor_6.01870,969,733 - 70,972,839 (+)NCBI
Rnor_5.01870,108,978 - 70,112,084 (+)NCBI
RGSC_v3.41871,863,062 - 71,866,168 (+)RGD
Celera1866,756,106 - 66,759,212 (+)RGD
Sequence:
RefSeq Acc Id: XM_039096639   ⟹   XP_038952567
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,856,290 - 70,859,388 (+)NCBI
mRatBN7.21868,581,372 - 68,584,253 (+)NCBI
RefSeq Acc Id: XM_063277167   ⟹   XP_063133237
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,856,312 - 70,859,388 (+)NCBI
RefSeq Acc Id: XM_063277168   ⟹   XP_063133238
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81870,856,275 - 70,859,388 (+)NCBI
RefSeq Acc Id: NP_958818   ⟸   NM_201415
- UniProtKB: Q4G093 (UniProtKB/Swiss-Prot),   P24049 (UniProtKB/Swiss-Prot),   D3Z9G9 (UniProtKB/TrEMBL),   A6KRH3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025217   ⟸   ENSRNOT00000025217
Ensembl Acc Id: ENSRNOP00000034364   ⟸   ENSRNOT00000039203
RefSeq Acc Id: XP_038952567   ⟸   XM_039096639
- Peptide Label: isoform X1
- UniProtKB: P24049 (UniProtKB/Swiss-Prot),   Q4G093 (UniProtKB/Swiss-Prot),   D3Z9G9 (UniProtKB/TrEMBL),   A6KRH3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133238   ⟸   XM_063277168
- Peptide Label: isoform X2
- UniProtKB: A6KRH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133237   ⟸   XM_063277167
- Peptide Label: isoform X1
- UniProtKB: Q4G093 (UniProtKB/Swiss-Prot),   P24049 (UniProtKB/Swiss-Prot),   A6KRH3 (UniProtKB/TrEMBL),   D3Z9G9 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P24049-F1-model_v2 AlphaFold P24049 1-184 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303019 AgrOrtholog
BioCyc Gene G2FUF-6995 BioCyc
Ensembl Genes ENSRNOG00000018680 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000029262 Ensembl
Ensembl Transcript ENSRNOT00000025217 ENTREZGENE
  ENSRNOT00000025217.7 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.470.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7129700 IMAGE-MGC_LOAD
InterPro Ribosomal_L22 UniProtKB/Swiss-Prot
  Ribosomal_L22/L17_CS UniProtKB/Swiss-Prot
  Ribosomal_L22/L17_euk/arc UniProtKB/Swiss-Prot
  Ribosomal_L22/L17_sf UniProtKB/Swiss-Prot
KEGG Report rno:291434 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112577 IMAGE-MGC_LOAD
NCBI Gene 291434 ENTREZGENE
PANTHER 60S RIBOSOMAL PROTEIN L17 UniProtKB/Swiss-Prot
  PTHR11593 UniProtKB/Swiss-Prot
Pfam Ribosomal_L22 UniProtKB/Swiss-Prot
PhenoGen Rpl17 PhenoGen
PROSITE RIBOSOMAL_L22 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018680 RatGTEx
  ENSRNOG00000029262 RatGTEx
Superfamily-SCOP SSF54843 UniProtKB/Swiss-Prot
UniProt A6KRH3 ENTREZGENE, UniProtKB/TrEMBL
  A6KRH4 ENTREZGENE, UniProtKB/TrEMBL
  D3Z9G9 ENTREZGENE, UniProtKB/TrEMBL
  P24049 ENTREZGENE
  Q4G093 ENTREZGENE
  RL17_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q4G093 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-02-14 Rpl17  ribosomal protein L17      Symbol and Name status set to provisional 70820 PROVISIONAL