LOC102550668 (60S ribosomal protein L21-like) - Rat Genome Database

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Pathways
Gene: LOC102550668 (60S ribosomal protein L21-like) Rattus norvegicus
Analyze
No known orthologs.
Symbol: LOC102550668 (Ensembl: AABR07043626.1)
Name: 60S ribosomal protein L21-like
RGD ID: 7700714
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Located in ribosome. Part of cytosolic large ribosomal subunit.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: large ribosomal subunit protein eL21-like; LOC291943; RGD1559531; similar to 60S ribosomal protein L21
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81946,360,998 - 46,361,583 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1946,361,116 - 46,361,583 (+)EnsemblGRCr8
mRatBN7.21929,456,838 - 29,457,305 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1929,456,838 - 29,457,305 (+)EnsemblmRatBN7.2
Rnor_6.01933,130,279 - 33,130,785 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01944,022,475 - 44,022,965 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41931,359,209 - 31,359,676 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1928,955,429 - 28,955,935 (+)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
translation  (IEA)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:3730400   PMID:7451403  


Genomics

Variants

.
Variants in LOC102550668
3 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
61328Eae8Experimental allergic encephalomyelitis QTL 84nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)194172060949971820Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)193128753251431640Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)194072709254856850Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)193009938347207961Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)194072709254856850Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)194072709254856850Rat


Expression

RNA-SEQ Expression

ectoderm
mesenchyme
nervous system
renal system
sensory system
visual system
2 1 2 1 1 1

Sequence


Ensembl Acc Id: ENSRNOT00000048673   ⟹   ENSRNOP00000039287
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1946,361,116 - 46,361,583 (+)Ensembl
mRatBN7.2 Ensembl1929,456,838 - 29,457,305 (+)Ensembl
RefSeq Acc Id: XM_039098195   ⟹   XP_038954123
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81946,360,998 - 46,361,583 (+)NCBI
mRatBN7.21929,456,838 - 29,457,305 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038954123 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000039287
  ENSRNOP00000039287.3
RefSeq Acc Id: XP_038954123   ⟸   XM_039098195
- UniProtKB: P20280 (UniProtKB/Swiss-Prot),   D3ZQ96 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000039287   ⟸   ENSRNOT00000048673

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZQ96-F1-model_v2 AlphaFold D3ZQ96 1-155 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:7700714 AgrOrtholog
BioCyc Gene G2FUF-5928 BioCyc
Ensembl Genes ENSRNOG00000033487 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000048673 ENTREZGENE
  ENSRNOT00000048673.5 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.70 UniProtKB/TrEMBL
  6.10.250.3260 UniProtKB/TrEMBL
InterPro Ribosomal_L21_sf UniProtKB/TrEMBL
  Ribosomal_L21e UniProtKB/TrEMBL
  Translation_prot_SH3-like_sf UniProtKB/TrEMBL
NCBI Gene LOC102550668 ENTREZGENE
PANTHER PTHR20981 UniProtKB/TrEMBL
Pfam Ribosomal_L21e UniProtKB/TrEMBL
PhenoGen LOC102550668 PhenoGen
RatGTEx ENSRNOG00000033487 RatGTEx
Superfamily-SCOP SSF50104 UniProtKB/TrEMBL
UniProt D3ZQ96 ENTREZGENE, UniProtKB/TrEMBL
  P20280 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 LOC102550668  60S ribosomal protein L21-like  RGD1559531  similar to 60S ribosomal protein L21  Data merged from RGD:1559531 737654 PROVISIONAL
2013-12-18 LOC102550668  60S ribosomal protein L21-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1559531  similar to 60S ribosomal protein L21   RGD1559531_predicted  similar to 60S ribosomal protein L21 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1559531_predicted  similar to 60S ribosomal protein L21 (predicted)  LOC291943  similar to 60S ribosomal protein L21  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC291943  similar to 60S ribosomal protein L21      Symbol and Name status set to provisional 70820 PROVISIONAL