Iqcn (IQ motif containing N) - Rat Genome Database

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Gene: Iqcn (IQ motif containing N) Rattus norvegicus
Analyze
Symbol: Iqcn
Name: IQ motif containing N
RGD ID: 7549926
Description: Predicted to be involved in spermatid development. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in spermatogenic failure. Orthologous to human IQCN (IQ motif containing N); INTERACTS WITH bisphenol A; paraquat; 15-acetyldeoxynivalenol (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: IQ domain-containing protein N; LOC102547294; LOC306346; mucin-17-like; similar to KIAA1683; uncharacterized protein KIAA1683 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,750,492 - 18,766,184 (-)NCBIGRCr8
mRatBN7.21618,716,519 - 18,733,971 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,716,519 - 18,726,261 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,758,451 - 18,773,053 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,891,390 - 19,906,139 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,811,400 - 18,826,003 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,467,425 - 20,483,375 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01620,324,493 - 20,339,412 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,222,176 - 19,223,162 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1618,908,707 - 18,924,642 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21630459  


Genomics

Comparative Map Data
Iqcn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,750,492 - 18,766,184 (-)NCBIGRCr8
mRatBN7.21618,716,519 - 18,733,971 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,716,519 - 18,726,261 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,758,451 - 18,773,053 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,891,390 - 19,906,139 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,811,400 - 18,826,003 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,467,425 - 20,483,375 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01620,324,493 - 20,339,412 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,222,176 - 19,223,162 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1618,908,707 - 18,924,642 (-)NCBICelera
Cytogenetic Map16p14NCBI
IQCN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,257,098 - 18,274,452 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,257,098 - 18,274,500 (-)EnsemblGRCh38hg38GRCh38
GRCh371918,367,908 - 18,385,262 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,228,908 - 18,246,235 (-)NCBINCBI36Build 36hg18NCBI36
Build 341918,228,907 - 18,246,235NCBI
Celera1918,269,630 - 18,287,045 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1917,931,567 - 17,948,982 (-)NCBIHuRef
CHM1_11918,368,170 - 18,385,585 (-)NCBICHM1_1
T2T-CHM13v2.01918,391,196 - 18,408,552 (-)NCBIT2T-CHM13v2.0
Iqcn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39871,154,661 - 71,170,299 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl871,156,106 - 71,170,299 (+)EnsemblGRCm39 Ensembl
GRCm38870,701,321 - 70,717,650 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,703,457 - 70,717,650 (+)EnsemblGRCm38mm10GRCm38
MGSCv37873,232,059 - 73,241,549 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,637,149 - 73,651,080 (+)NCBIMGSCv36mm8
Celera873,264,658 - 73,274,148 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Iqcn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555243,181,133 - 3,195,111 (+)NCBIChiLan1.0ChiLan1.0
IQCN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,114,554 - 23,132,163 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,122,872 - 22,140,388 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01917,732,673 - 17,750,226 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11918,708,154 - 18,719,269 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,708,155 - 18,719,021 (-)Ensemblpanpan1.1panPan2
IQCN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,743,889 - 44,758,625 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,745,584 - 44,758,637 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,658,051 - 44,672,793 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02045,229,714 - 45,244,539 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12044,466,869 - 44,481,627 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,877,601 - 44,892,330 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02045,152,767 - 45,167,506 (+)NCBIUU_Cfam_GSD_1.0
Iqcn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,393,995 - 203,406,713 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,944,534 - 2,955,765 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
IQCN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1259,545,325 - 59,558,077 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
IQCN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,732,296 - 16,745,050 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660742,632,811 - 2,643,498 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Iqcn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249081,558,560 - 1,583,275 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Iqcn
75 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161572643321034895Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000097349   ⟹   ENSRNOP00000088555
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,716,519 - 18,726,261 (-)Ensembl
RefSeq Acc Id: NM_001399437   ⟹   NP_001386366
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,750,492 - 18,765,386 (-)NCBI
mRatBN7.21618,716,519 - 18,731,414 (-)NCBI
RefSeq Acc Id: XM_006252972   ⟹   XP_006253034
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,750,492 - 18,766,184 (-)NCBI
mRatBN7.21618,716,519 - 18,733,971 (-)NCBI
Rnor_6.01620,468,408 - 20,483,375 (-)NCBI
Rnor_5.01620,324,493 - 20,339,412 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252973   ⟹   XP_006253035
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,750,492 - 18,766,184 (-)NCBI
mRatBN7.21618,716,519 - 18,733,971 (-)NCBI
Rnor_6.01620,468,408 - 20,483,375 (-)NCBI
Rnor_5.01620,324,493 - 20,339,412 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252974   ⟹   XP_006253036
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,750,492 - 18,766,184 (-)NCBI
mRatBN7.21618,716,519 - 18,730,829 (-)NCBI
Rnor_6.01620,468,408 - 20,481,651 (-)NCBI
Rnor_5.01620,324,493 - 20,339,412 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600334   ⟹   XP_017455823
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,750,492 - 18,766,184 (-)NCBI
mRatBN7.21618,716,519 - 18,733,971 (-)NCBI
Rnor_6.01620,467,425 - 20,482,661 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063274973   ⟹   XP_063131043
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,750,492 - 18,766,184 (-)NCBI
RefSeq Acc Id: XM_063274974   ⟹   XP_063131044
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,750,492 - 18,766,184 (-)NCBI
RefSeq Acc Id: XM_063274975   ⟹   XP_063131045
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,750,492 - 18,766,184 (-)NCBI
RefSeq Acc Id: XM_063274976   ⟹   XP_063131046
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,750,492 - 18,766,184 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_006253035   ⟸   XM_006252973
- Peptide Label: isoform X1
- UniProtKB: A6KA10 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253034   ⟸   XM_006252972
- Peptide Label: isoform X1
- UniProtKB: A6KA10 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253036   ⟸   XM_006252974
- Peptide Label: isoform X1
- UniProtKB: A6KA10 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017455823   ⟸   XM_017600334
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000088555   ⟸   ENSRNOT00000097349
RefSeq Acc Id: NP_001386366   ⟸   NM_001399437
RefSeq Acc Id: XP_063131045   ⟸   XM_063274975
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063131044   ⟸   XM_063274974
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063131046   ⟸   XM_063274976
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063131043   ⟸   XM_063274973
- Peptide Label: isoform X2

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:7549926 AgrOrtholog
BioCyc Gene G2FUF-11799 BioCyc
Ensembl Genes ENSRNOG00000068146 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000097349.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.190 UniProtKB/TrEMBL
InterPro IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene LOC102547294 ENTREZGENE
PANTHER PTHR22590:SF2 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam PF00612 UniProtKB/TrEMBL
PhenoGen Iqcn PhenoGen
PROSITE PS50096 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000068146 RatGTEx
SMART SM00015 UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8I6GGC3_RAT UniProtKB/TrEMBL
  A6KA10 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Iqcn  IQ motif containing N  Iqcn  IQ motif containing N  Data merged from RGD:149736523 737654 PROVISIONAL
2021-08-09 Iqcn  IQ motif containing N      Symbol and Name status set to provisional 45752 PROVISIONAL
2017-11-17 Iqcn  IQ motif containing N  LOC102547294  mucin-17-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-29 LOC102547294  mucin-17-like  LOC306346  similar to KIAA1683  Data merged from RGD:1588554 737654 PROVISIONAL
2013-12-17 LOC102547294  mucin-17-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC306346  similar to KIAA1683      Symbol and Name status set to provisional 70820 PROVISIONAL