Atp6v1e1 (ATPase H+ transporting V1 subunit E1) - Rat Genome Database

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Gene: Atp6v1e1 (ATPase H+ transporting V1 subunit E1) Rattus norvegicus
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Symbol: Atp6v1e1
Name: ATPase H+ transporting V1 subunit E1
RGD ID: 735157
Description: Predicted to enable ATPase binding activity and proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in synaptic vesicle lumen acidification. Predicted to act upstream of or within proton transmembrane transport. Part of vacuolar proton-transporting V-type ATPase, V1 domain. Is extrinsic component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIC. Orthologous to human ATP6V1E1 (ATPase H+ transporting V1 subunit E1); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Atp6e; Atp6e2; ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E; ATPase, H+ transporting, lysosomal V1 subunit E1; ATPase, H+ transporting, V1 subunit E; ATPase, H+ transporting, V1 subunit E isoform 1; MGC72933; P31; Unknown (protein for MGC:72933); V-ATPase subunit E 1; V-type proton ATPase subunit E 1; vacuolar H(+)-ATPase, E subunit; vacuolar H+ ATPase E1; vacuolar proton pump subunit E 1; VATPase, H+ transporting, lysosomal V1 subunit E1; Vma4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84155,694,534 - 155,716,660 (-)NCBIGRCr8
mRatBN7.24154,022,358 - 154,044,486 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4154,022,358 - 154,044,584 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4160,287,788 - 160,309,985 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04156,071,525 - 156,093,723 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04154,694,845 - 154,717,044 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04153,351,434 - 153,373,558 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4153,351,421 - 153,373,649 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04220,441,646 - 220,463,691 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44157,203,842 - 157,225,966 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14157,448,682 - 157,470,807 (-)NCBI
Celera4142,863,533 - 142,885,658 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structure of V-ATPase from the mammalian brain. Abbas YM, etal., Science. 2020 Mar 13;367(6483):1240-1246. doi: 10.1126/science.aaz2924.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. The amino-terminal domain of the E subunit of vacuolar H(+)-ATPase (V-ATPase) interacts with the H subunit and is required for V-ATPase function. Lu M, etal., J Biol Chem 2002 Oct 11;277(41):38409-15. Epub 2002 Aug 05.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11423561   PMID:11872743   PMID:14651853   PMID:15489334   PMID:16177003   PMID:16267653   PMID:17897319   PMID:18667600   PMID:19056867   PMID:19199708   PMID:20717956   PMID:22871113  
PMID:23376485   PMID:29476059   PMID:32357304  


Genomics

Comparative Map Data
Atp6v1e1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84155,694,534 - 155,716,660 (-)NCBIGRCr8
mRatBN7.24154,022,358 - 154,044,486 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4154,022,358 - 154,044,584 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4160,287,788 - 160,309,985 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04156,071,525 - 156,093,723 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04154,694,845 - 154,717,044 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04153,351,434 - 153,373,558 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4153,351,421 - 153,373,649 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04220,441,646 - 220,463,691 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44157,203,842 - 157,225,966 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14157,448,682 - 157,470,807 (-)NCBI
Celera4142,863,533 - 142,885,658 (-)NCBICelera
Cytogenetic Map4q42NCBI
ATP6V1E1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382217,592,136 - 17,628,822 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2217,592,136 - 17,628,749 (-)EnsemblGRCh38hg38GRCh38
GRCh372218,074,902 - 18,111,588 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362216,454,902 - 16,491,588 (-)NCBINCBI36Build 36hg18NCBI36
Build 342216,449,478 - 16,486,089NCBI
Celera221,694,652 - 1,731,337 (-)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef221,890,227 - 1,926,475 (-)NCBIHuRef
CHM1_12218,074,451 - 18,110,848 (-)NCBICHM1_1
T2T-CHM13v2.02218,259,880 - 18,296,566 (-)NCBIT2T-CHM13v2.0
Atp6v1e1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396120,772,205 - 120,799,659 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6120,771,266 - 120,799,754 (-)EnsemblGRCm39 Ensembl
GRCm386120,795,244 - 120,822,698 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6120,794,305 - 120,822,793 (-)EnsemblGRCm38mm10GRCm38
MGSCv376120,745,262 - 120,772,703 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366120,760,863 - 120,788,304 (-)NCBIMGSCv36mm8
Celera6122,637,400 - 122,665,943 (-)NCBICelera
Cytogenetic Map6F1NCBI
cM Map657.01NCBI
Atp6v1e1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554545,666,921 - 5,688,645 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554545,669,883 - 5,688,623 (-)NCBIChiLan1.0ChiLan1.0
ATP6V1E1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22327,910,429 - 27,946,816 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12230,457,953 - 30,494,431 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0221,023,028 - 1,059,416 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12216,452,358 - 16,486,902 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2216,452,358 - 16,486,902 (-)Ensemblpanpan1.1panPan2
ATP6V1E1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12745,222,647 - 45,249,317 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha271,434,437 - 1,460,750 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02745,592,265 - 45,618,871 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2745,592,270 - 45,626,233 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12745,520,711 - 45,547,059 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02745,493,999 - 45,520,299 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.027788,311 - 814,762 (+)NCBIUU_Cfam_GSD_1.0
Atp6v1e1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945110,349,716 - 110,375,182 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936807570,872 - 596,444 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936807570,952 - 596,383 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP6V1E1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl569,747,700 - 69,771,990 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1569,752,644 - 69,772,038 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2572,025,380 - 72,045,336 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Atp6v1e1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247359,703,863 - 9,726,275 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247359,704,600 - 9,726,297 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Atp6v1e1
100 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:57
Count of miRNA genes:51
Interacting mature miRNAs:55
Transcripts:ENSRNOT00000016495
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4109827074154827074Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4109827074154827074Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110870972155870972Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4114627026159627026Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4119428175157578333Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123143783168143783Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4124778595169778595Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4125590636170590636Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4132642577167139601Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4146565735175236377Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4147278504167139601Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
61446Coreg2Compensatory renal growth QTL 23.5kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)4148423102157580971Rat
1581574Eae20Experimental allergic encephalomyelitis QTL 207.8nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)4153031106158841762Rat

Markers in Region
AA818483  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24154,022,513 - 154,022,705 (+)MAPPERmRatBN7.2
Rnor_6.04153,351,588 - 153,351,779NCBIRnor6.0
Rnor_5.04220,441,800 - 220,441,991UniSTSRnor5.0
RGSC_v3.44157,203,996 - 157,204,187UniSTSRGSC3.4
Celera4142,863,687 - 142,863,878UniSTS
RH 3.4 Map4997.5UniSTS
Cytogenetic Map4q42UniSTS
RH79089  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24154,034,951 - 154,035,792 (+)MAPPERmRatBN7.2
Rnor_6.04153,364,025 - 153,364,865NCBIRnor6.0
Rnor_5.04220,454,236 - 220,455,076UniSTSRnor5.0
RGSC_v3.44157,216,433 - 157,217,273UniSTSRGSC3.4
Celera4142,876,124 - 142,876,964UniSTS
Cytogenetic Map4q42UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_198745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC123213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000016495   ⟹   ENSRNOP00000016495
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4154,022,359 - 154,044,584 (-)Ensembl
Rnor_6.0 Ensembl4153,351,421 - 153,373,649 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000098217   ⟹   ENSRNOP00000096225
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4154,022,358 - 154,040,374 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114868   ⟹   ENSRNOP00000090055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4154,026,845 - 154,044,495 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118257   ⟹   ENSRNOP00000087219
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4154,022,358 - 154,040,177 (-)Ensembl
RefSeq Acc Id: NM_198745   ⟹   NP_942040
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84155,694,534 - 155,716,660 (-)NCBI
mRatBN7.24154,022,358 - 154,044,486 (-)NCBI
Rnor_6.04153,351,434 - 153,373,558 (-)NCBI
Rnor_5.04220,441,646 - 220,463,691 (-)NCBI
RGSC_v3.44157,203,842 - 157,225,966 (-)RGD
Celera4142,863,533 - 142,885,658 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_942040 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH59155 (Get FASTA)   NCBI Sequence Viewer  
  EDM02027 (Get FASTA)   NCBI Sequence Viewer  
  EDM02028 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000016495
  ENSRNOP00000016495.4
  ENSRNOP00000087219.1
  ENSRNOP00000090055.1
  ENSRNOP00000096225.1
GenBank Protein Q6PCU2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_942040   ⟸   NM_198745
- UniProtKB: Q6PCU2 (UniProtKB/Swiss-Prot),   G3V7L8 (UniProtKB/TrEMBL),   A6ILB2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000016495   ⟸   ENSRNOT00000016495
RefSeq Acc Id: ENSRNOP00000090055   ⟸   ENSRNOT00000114868
RefSeq Acc Id: ENSRNOP00000096225   ⟸   ENSRNOT00000098217
RefSeq Acc Id: ENSRNOP00000087219   ⟸   ENSRNOT00000118257

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6PCU2-F1-model_v2 AlphaFold Q6PCU2 1-226 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693358
Promoter ID:EPDNEW_R3882
Type:initiation region
Name:Atp6v1e1_1
Description:ATPase H+ transporting V1 subunit E1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04153,373,526 - 153,373,586EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735157 AgrOrtholog
BioCyc Gene G2FUF-43190 BioCyc
BioCyc Pathway PWY-7980 [ATP biosynthesis] BioCyc
BioCyc Pathway Image PWY-7980 BioCyc
Ensembl Genes ENSRNOG00000011905 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016495 ENTREZGENE
  ENSRNOT00000016495.7 UniProtKB/TrEMBL
  ENSRNOT00000098217.1 UniProtKB/TrEMBL
  ENSRNOT00000114868.1 UniProtKB/TrEMBL
  ENSRNOT00000118257.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.2320.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.250.1620 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6887702 IMAGE-MGC_LOAD
InterPro ATPase_E_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATPase_V1_Esu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:297566 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72933 IMAGE-MGC_LOAD
NCBI Gene 297566 ENTREZGENE
PANTHER PTHR45715 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V-TYPE PROTON ATPASE SUBUNIT E 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam vATP-synt_E UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Atp6v1e1 PhenoGen
RatGTEx ENSRNOG00000011905 RatGTEx
Superfamily-SCOP V-type ATPase subunit E-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A8J4_RAT UniProtKB/TrEMBL
  A0A8I6B3W0_RAT UniProtKB/TrEMBL
  A0A8I6GFS9_RAT UniProtKB/TrEMBL
  A6ILB1_RAT UniProtKB/TrEMBL
  A6ILB2 ENTREZGENE, UniProtKB/TrEMBL
  G3V7L8 ENTREZGENE, UniProtKB/TrEMBL
  Q6PCU2 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-25 Atp6v1e1  ATPase H+ transporting V1 subunit E1  Atp6v1e1  ATPase, H+ transporting, lysosomal V1 subunit E1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-06-27 Atp6v1e1  ATPase, H+ transporting, lysosomal V1 subunit E1  Atp6v1e1  VATPase, H+ transporting, lysosomal V1 subunit E1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-03 Atp6v1e1  VATPase, H+ transporting, lysosomal V1 subunit E1  Atp6v1e1  ATPase, H+ transporting, V1 subunit E isoform 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Atp6v1e1  ATPase, H+ transporting, V1 subunit E isoform 1  MGC72933  Unknown (protein for MGC:72933)  Symbol and Name updated 1299863 APPROVED