Ica1l (islet cell autoantigen 1-like) - Rat Genome Database

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Gene: Ica1l (islet cell autoantigen 1-like) Rattus norvegicus
Analyze
Symbol: Ica1l
Name: islet cell autoantigen 1-like
RGD ID: 735110
Description: Predicted to enable protein domain specific binding activity. Predicted to be involved in regulation of transport. Predicted to act upstream of or within spermatid development. Predicted to be located in acrosomal vesicle. Predicted to be active in Golgi apparatus. Orthologous to human ICA1L (islet cell autoantigen 1 like); INTERACTS WITH bisphenol A; cadmium dichloride; fenvalerate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein homolog; Ica69-related protein; islet cell autoantigen 1, 69kDa-like; islet cell autoantigen 1-like protein; LOC316432
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,906,148 - 68,964,078 (-)NCBIGRCr8
mRatBN7.2961,410,959 - 61,469,884 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,412,091 - 61,470,134 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx969,914,281 - 69,950,389 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0975,029,835 - 75,065,943 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,348,547 - 73,384,653 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0966,788,094 - 66,848,958 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,790,047 - 66,845,403 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0966,599,967 - 66,659,239 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4958,549,961 - 58,588,146 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1958,696,942 - 58,735,128 (-)NCBI
Celera958,848,507 - 58,883,908 (-)NCBICelera
Cytogenetic Map9q31-q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Islet cell autoantigen of 69 kDa is an arfaptin-related protein associated with the Golgi complex of insulinoma INS-1 cells. Spitzenberger F, etal., J Biol Chem 2003 Jul 11;278(28):26166-73.
Additional References at PubMed
PMID:26306493  


Genomics

Comparative Map Data
Ica1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,906,148 - 68,964,078 (-)NCBIGRCr8
mRatBN7.2961,410,959 - 61,469,884 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,412,091 - 61,470,134 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx969,914,281 - 69,950,389 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0975,029,835 - 75,065,943 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,348,547 - 73,384,653 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0966,788,094 - 66,848,958 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,790,047 - 66,845,403 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0966,599,967 - 66,659,239 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4958,549,961 - 58,588,146 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1958,696,942 - 58,735,128 (-)NCBI
Celera958,848,507 - 58,883,908 (-)NCBICelera
Cytogenetic Map9q31-q32NCBI
ICA1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382202,773,176 - 202,871,766 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2202,773,150 - 202,871,766 (-)EnsemblGRCh38hg38GRCh38
GRCh372203,637,899 - 203,736,489 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362203,346,118 - 203,444,616 (-)NCBINCBI36Build 36hg18NCBI36
Build 342203,467,301 - 203,561,871NCBI
Celera2197,390,623 - 197,489,058 (-)NCBICelera
Cytogenetic Map2q33.2NCBI
HuRef2195,484,776 - 195,583,236 (-)NCBIHuRef
CHM1_12203,644,501 - 203,742,964 (-)NCBICHM1_1
T2T-CHM13v2.02203,254,630 - 203,353,223 (-)NCBIT2T-CHM13v2.0
Ica1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39160,024,955 - 60,082,646 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl160,021,649 - 60,082,343 (-)EnsemblGRCm39 Ensembl
GRCm38159,985,796 - 60,043,481 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl159,982,490 - 60,043,184 (-)EnsemblGRCm38mm10GRCm38
MGSCv37160,045,912 - 60,099,931 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36159,933,614 - 59,987,633 (-)NCBIMGSCv36mm8
Celera160,504,490 - 60,558,846 (-)NCBICelera
Cytogenetic Map1C2NCBI
cM Map130.45NCBI
Ica1l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545712,006,306 - 12,085,799 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545711,983,201 - 12,085,870 (+)NCBIChiLan1.0ChiLan1.0
ICA1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213105,406,392 - 105,475,098 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B105,421,389 - 105,490,094 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B90,034,205 - 90,105,600 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B208,184,023 - 208,252,084 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B208,184,023 - 208,251,254 (-)Ensemblpanpan1.1panPan2
ICA1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13711,674,970 - 11,754,931 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3711,678,125 - 11,741,997 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3712,558,653 - 12,638,491 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03711,611,993 - 11,691,866 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3711,613,496 - 11,691,338 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13711,568,391 - 11,648,134 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03711,539,667 - 11,619,487 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03711,533,517 - 11,613,396 (-)NCBIUU_Cfam_GSD_1.0
Ica1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303159,877,981 - 159,952,434 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367261,853,868 - 1,902,788 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367261,853,178 - 1,922,684 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ICA1L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15106,295,934 - 106,377,579 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115106,293,936 - 106,377,573 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215117,753,375 - 117,827,860 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ICA1L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11088,492,255 - 88,609,268 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1088,517,716 - 88,569,031 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040110,776,859 - 110,874,196 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ica1l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476513,588,073 - 13,687,250 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476513,547,437 - 13,687,641 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ica1l
299 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:29
Count of miRNA genes:29
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000041546
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)94996854671098346Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95584784177026453Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)95662771378595166Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
1578659Tspe1Trichinella spiralis expulsion QTL 14.8parasite quantity (VT:0010441)logarithm of the intestinal adult Trichinella spiralis count (CMO:0002024)96138143465691299Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat

Markers in Region
BF413809  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,425,984 - 61,426,090 (+)MAPPERmRatBN7.2
Rnor_6.0966,801,989 - 66,802,094NCBIRnor6.0
Rnor_5.0966,613,858 - 66,613,963UniSTSRnor5.0
RGSC_v3.4958,561,730 - 58,561,835UniSTSRGSC3.4
Celera958,860,276 - 58,860,381UniSTS
RH 3.4 Map9495.8UniSTS
Cytogenetic Map9q31UniSTS
RH133804  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,413,720 - 61,413,940 (+)MAPPERmRatBN7.2
Rnor_6.0966,789,725 - 66,789,944NCBIRnor6.0
Rnor_5.0966,601,594 - 66,601,813UniSTSRnor5.0
RGSC_v3.4958,549,466 - 58,549,685UniSTSRGSC3.4
Celera958,848,012 - 58,848,231UniSTS
RH 3.4 Map9496.3UniSTS
Cytogenetic Map9q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 9 31 113 71 70 39 25 39 6 178 77 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_199400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039083638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC129370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY491990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000041546   ⟹   ENSRNOP00000045103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,412,091 - 61,450,546 (-)Ensembl
Rnor_6.0 Ensembl966,790,047 - 66,845,403 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094628   ⟹   ENSRNOP00000094417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,412,091 - 61,470,134 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119954   ⟹   ENSRNOP00000076459
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,412,091 - 61,470,134 (-)Ensembl
RefSeq Acc Id: NM_199400   ⟹   NP_955432
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,692 (-)NCBI
mRatBN7.2961,412,090 - 61,469,638 (-)NCBI
Rnor_6.0966,790,220 - 66,825,834 (-)NCBI
Rnor_5.0966,599,967 - 66,659,239 (-)NCBI
RGSC_v3.4958,549,961 - 58,588,146 (-)RGD
Celera958,848,507 - 58,883,908 (-)RGD
Sequence:
RefSeq Acc Id: XM_006244994   ⟹   XP_006245056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,518 (-)NCBI
mRatBN7.2961,410,959 - 61,469,468 (-)NCBI
Rnor_6.0966,788,094 - 66,845,406 (-)NCBI
Rnor_5.0966,599,967 - 66,659,239 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006244995   ⟹   XP_006245057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,517 (-)NCBI
mRatBN7.2961,410,959 - 61,469,467 (-)NCBI
Rnor_6.0966,788,094 - 66,845,406 (-)NCBI
Rnor_5.0966,599,967 - 66,659,239 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006244999   ⟹   XP_006245061
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,518 (-)NCBI
mRatBN7.2961,410,959 - 61,469,468 (-)NCBI
Rnor_6.0966,788,094 - 66,845,406 (-)NCBI
Rnor_5.0966,599,967 - 66,659,239 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008767111   ⟹   XP_008765333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,521 (-)NCBI
mRatBN7.2961,412,088 - 61,469,470 (-)NCBI
Rnor_6.0966,788,094 - 66,845,406 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596461   ⟹   XP_017451950
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,518 (-)NCBI
mRatBN7.2961,410,959 - 61,469,468 (-)NCBI
Rnor_6.0966,788,094 - 66,845,406 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596464   ⟹   XP_017451953
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,964,078 (-)NCBI
mRatBN7.2961,412,088 - 61,469,884 (-)NCBI
Rnor_6.0966,788,094 - 66,848,958 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083634   ⟹   XP_038939562
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,520 (-)NCBI
mRatBN7.2961,410,959 - 61,469,470 (-)NCBI
RefSeq Acc Id: XM_039083635   ⟹   XP_038939563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
mRatBN7.2961,410,959 - 61,469,621 (-)NCBI
RefSeq Acc Id: XM_039083636   ⟹   XP_038939564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,518 (-)NCBI
mRatBN7.2961,410,959 - 61,469,468 (-)NCBI
RefSeq Acc Id: XM_039083637   ⟹   XP_038939565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,518 (-)NCBI
mRatBN7.2961,410,959 - 61,469,468 (-)NCBI
RefSeq Acc Id: XM_039083638   ⟹   XP_038939566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,943,779 (-)NCBI
mRatBN7.2961,410,959 - 61,449,727 (-)NCBI
RefSeq Acc Id: XM_063267202   ⟹   XP_063123272
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,519 (-)NCBI
RefSeq Acc Id: XM_063267203   ⟹   XP_063123273
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,519 (-)NCBI
RefSeq Acc Id: XM_063267204   ⟹   XP_063123274
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
RefSeq Acc Id: XM_063267205   ⟹   XP_063123275
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,519 (-)NCBI
RefSeq Acc Id: XM_063267206   ⟹   XP_063123276
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,737 (-)NCBI
RefSeq Acc Id: XM_063267207   ⟹   XP_063123277
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
RefSeq Acc Id: XM_063267208   ⟹   XP_063123278
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
RefSeq Acc Id: XM_063267209   ⟹   XP_063123279
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
RefSeq Acc Id: XM_063267210   ⟹   XP_063123280
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
RefSeq Acc Id: XM_063267211   ⟹   XP_063123281
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
RefSeq Acc Id: XM_063267212   ⟹   XP_063123282
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,906,148 - 68,963,738 (-)NCBI
Protein Sequences
Protein RefSeqs NP_955432 (Get FASTA)   NCBI Sequence Viewer  
  XP_006245056 (Get FASTA)   NCBI Sequence Viewer  
  XP_006245057 (Get FASTA)   NCBI Sequence Viewer  
  XP_006245061 (Get FASTA)   NCBI Sequence Viewer  
  XP_008765333 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451950 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451953 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939562 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939563 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939564 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939565 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939566 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123272 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123273 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123274 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123275 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123276 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123277 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123278 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123279 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123280 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123281 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123282 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAR36901 (Get FASTA)   NCBI Sequence Viewer  
  EDL98942 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000045103.3
  ENSRNOP00000076459.1
  ENSRNOP00000094417.1
GenBank Protein Q6RUG5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_955432   ⟸   NM_199400
- UniProtKB: Q6RUG5 (UniProtKB/Swiss-Prot),   A0A0H2UHX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245061   ⟸   XM_006244999
- Peptide Label: isoform X13
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245057   ⟸   XM_006244995
- Peptide Label: isoform X4
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL),   A0A8I6AM57 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245056   ⟸   XM_006244994
- Peptide Label: isoform X1
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765333   ⟸   XM_008767111
- Peptide Label: isoform X3
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451953   ⟸   XM_017596464
- Peptide Label: isoform X7
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451950   ⟸   XM_017596461
- Peptide Label: isoform X6
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000045103   ⟸   ENSRNOT00000041546
RefSeq Acc Id: XP_038939563   ⟸   XM_039083635
- Peptide Label: isoform X7
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939562   ⟸   XM_039083634
- Peptide Label: isoform X2
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939565   ⟸   XM_039083637
- Peptide Label: isoform X20
RefSeq Acc Id: XP_038939564   ⟸   XM_039083636
- Peptide Label: isoform X16
- UniProtKB: A0A0H2UHX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939566   ⟸   XM_039083638
- Peptide Label: isoform X21
Ensembl Acc Id: ENSRNOP00000094417   ⟸   ENSRNOT00000094628
Ensembl Acc Id: ENSRNOP00000076459   ⟸   ENSRNOT00000119954
RefSeq Acc Id: XP_063123278   ⟸   XM_063267208
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063123274   ⟸   XM_063267204
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063123281   ⟸   XM_063267211
- Peptide Label: isoform X18
RefSeq Acc Id: XP_063123277   ⟸   XM_063267207
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063123282   ⟸   XM_063267212
- Peptide Label: isoform X19
RefSeq Acc Id: XP_063123280   ⟸   XM_063267210
- Peptide Label: isoform X17
- UniProtKB: A0A8I5XZZ8 (UniProtKB/TrEMBL),   A6IPB8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123279   ⟸   XM_063267209
- Peptide Label: isoform X15
- UniProtKB: Q6RUG5 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063123276   ⟸   XM_063267206
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063123273   ⟸   XM_063267203
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063123275   ⟸   XM_063267205
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063123272   ⟸   XM_063267202
- Peptide Label: isoform X5
Protein Domains
AH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6RUG5-F1-model_v2 AlphaFold Q6RUG5 1-435 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735110 AgrOrtholog
BioCyc Gene G2FUF-27386 BioCyc
Ensembl Genes ENSRNOG00000017258 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041546.3 UniProtKB/TrEMBL
  ENSRNOT00000094628.1 UniProtKB/TrEMBL
  ENSRNOT00000119954.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AH/BAR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Islet_autoAg_Ica1/Ica1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Islet_autoAg_Ica1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:316432 UniProtKB/Swiss-Prot
NCBI Gene 316432 ENTREZGENE
PANTHER ISLET CELL AUTOANTIGEN 1-LIKE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10164 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Arfaptin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ICA69 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ica1l PhenoGen
PROSITE PS50870 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017258 RatGTEx
SMART Arfaptin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ICA69 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0H2UHX6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5XZZ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AM57 ENTREZGENE, UniProtKB/TrEMBL
  A6IPB8 ENTREZGENE, UniProtKB/TrEMBL
  ICA1L_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-05 Ica1l  islet cell autoantigen 1-like  LOC316432  Ica69-related protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-30 LOC316432        Symbol and Name status set to provisional 70820 PROVISIONAL