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Gene: Myh1 (myosin heavy chain 1) Rattus norvegicus

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Symbol:

Myh1

Name:

myosin heavy chain 1 (Ensembl:myosin heavy chain 4)

RGD ID:

735061

Description:

Orthologous to human MYH1 (myosin heavy chain 1); PARTICIPATES IN myocarditis pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

MYHC; myosin, heavy chain 1, skeletal muscle, adult; myosin, heavy polypeptide 1, skeletal muscle, adult; type 2X myosin heavy chain

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	52,384,810 - 52,408,698 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	52,384,908 - 52,409,047 (+)	Ensembl				GRCr8
mRatBN7.2	10	51,885,913 - 51,909,699 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	51,885,913 - 51,946,295 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	56,542,792 - 56,566,565 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	56,031,797 - 56,055,568 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	51,542,188 - 51,565,983 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	10	55,323,487 - 55,347,273 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	10	55,983,577 - 56,007,346 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	10	57,648,472 - 57,672,258 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	10	57,567,815 - 57,591,584 (+)	NCBI		F344_StmMcwi
Rnor_6.0	10	53,740,841 - 53,764,610 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	53,713,938 - 53,848,347 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	53,493,997 - 53,517,766 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	53,894,388 - 53,917,948 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	51,068,765 - 51,092,552 (+)	NCBI		Celera
RGSC_v3.1	10	53,928,512 - 53,931,551 (+)	NCBI
Cytogenetic Map	10	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

6-propyl-2-thiouracil (EXP)

aconitine (EXP)

acrylamide (EXP)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

boric acid (ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (EXP,ISO)

cadmium dichloride (EXP,ISO)

capsaicin (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (EXP)

chromium(6+) (ISO)

chrysene (ISO)

ciguatoxin CTX1B (ISO)

ciprofibrate (ISO)

Cuprizon (EXP)

curcumin (EXP)

D-glucose (ISO)

dexamethasone (EXP)

diisononyl phthalate (ISO)

folic acid (ISO)

fructose (ISO)

furan (EXP)

glucose (ISO)

glycidol (EXP)

mono(2-ethylhexyl) phthalate (ISO)

N-nitrosodiethylamine (ISO)

nickel sulfate (ISO)

paracetamol (ISO)

phenobarbital (ISO)

phenol red (ISO)

pioglitazone (ISO)

pirinixic acid (ISO)

potassium bromate (ISO)

progesterone (ISO)

pyrrolidine dithiocarbamate (ISO)

quercetin (EXP)

sodium fluoride (ISO)

spermine (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

trichloroethene (EXP)

Triptolide (ISO)

vitamin K (EXP)

warfarin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

muscle contraction (IDA)

sensory perception of sound (IEA,ISO)

striated muscle contraction (TAS)

Cellular Component

A band (IEA,ISO)

cytoplasmic ribonucleoprotein granule (IEA,ISO)

intercalated disc (IEA,ISO)

muscle myosin complex (IDA,IEA,ISO)

myofibril (IEA)

myosin complex (IEA)

myosin filament (IEA)

Molecular Function

actin binding (IEA)

actin filament binding (IEA)

ATP binding (IEA)

ATP hydrolysis activity (TAS)

calmodulin binding (IEA)

cytoskeletal motor activity (IEA)

microfilament motor activity (TAS)

nucleotide binding (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

myocarditis pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Coupled expression of troponin T and troponin I isoforms in single skeletal muscle fibers correlates with contractility.	Brotto MA, etal., Am J Physiol Cell Physiol. 2006 Feb;290(2):C567-76. Epub 2005 Sep 28.
2.	Type 2X-myosin heavy chain is coded by a muscle fiber type-specific and developmentally regulated gene.	DeNardi C, etal., J Cell Biol 1993 Nov;123(4):823-35.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8287498	PMID:10460968	PMID:11732910	PMID:15121898	PMID:15578571	PMID:16839454	PMID:17030512	PMID:17670891	PMID:18310078	PMID:18761673	PMID:19369448	PMID:19738937
PMID:22206666	PMID:22464481	PMID:23058369	PMID:33573052

Genomics

Comparative Map Data

Myh1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	52,384,810 - 52,408,698 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	52,384,908 - 52,409,047 (+)	Ensembl				GRCr8
mRatBN7.2	10	51,885,913 - 51,909,699 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	51,885,913 - 51,946,295 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	56,542,792 - 56,566,565 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	56,031,797 - 56,055,568 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	51,542,188 - 51,565,983 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	10	55,323,487 - 55,347,273 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	10	55,983,577 - 56,007,346 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	10	57,648,472 - 57,672,258 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	10	57,567,815 - 57,591,584 (+)	NCBI		F344_StmMcwi
Rnor_6.0	10	53,740,841 - 53,764,610 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	53,713,938 - 53,848,347 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	53,493,997 - 53,517,766 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	53,894,388 - 53,917,948 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	51,068,765 - 51,092,552 (+)	NCBI		Celera
RGSC_v3.1	10	53,928,512 - 53,931,551 (+)	NCBI
Cytogenetic Map	10	q24	NCBI

MYH1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	10,492,307 - 10,518,542 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	10,491,389 - 10,518,719 (-)	Ensembl			hg38	GRCh38
GRCh37	17	10,395,624 - 10,421,859 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	10,336,349 - 10,362,584 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	17	10,336,352 - 10,360,684	NCBI
Celera	17	10,426,467 - 10,452,723 (-)	NCBI		Celera
Cytogenetic Map	17	p13.1	NCBI
HuRef	17	10,295,198 - 10,321,455 (-)	NCBI		HuRef
CHM1_1	17	10,405,462 - 10,431,716 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	10,399,791 - 10,426,053 (-)	NCBI		T2T-CHM13v2.0

Myh1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	67,090,922 - 67,115,401 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	67,090,878 - 67,115,401 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	67,200,102 - 67,224,577 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	67,200,052 - 67,224,575 (+)	Ensembl			mm10	GRCm38
MGSCv37	11	67,013,616 - 67,038,077 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	67,016,309 - 67,040,770 (+)	NCBI		MGSCv36	mm8
Celera	11	74,138,951 - 74,163,820 (+)	NCBI		Celera
Cytogenetic Map	11	B3	NCBI
cM Map	11	40.59	NCBI

Myh1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955467	6,685,753 - 6,707,491 (+)	Ensembl
ChiLan1.0	NW_004955467	6,684,104 - 6,707,597 (+)	NCBI	ChiLan1.0	ChiLan1.0

MYH1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	63,230,666 - 63,257,025 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	68,041,211 - 68,067,576 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	41,134,861 - 41,161,226 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	45,882,261 - 45,908,472 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	45,882,261 - 45,908,467 (+)	Ensembl			panPan2	panpan1.1

MYH2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	34,810,791 - 34,838,177 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	34,810,921 - 34,837,904 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	34,947,344 - 34,972,447 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	34,915,611 - 34,943,047 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	34,915,741 - 34,942,730 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	34,881,239 - 34,906,337 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	34,838,682 - 34,863,782 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	35,019,632 - 35,044,733 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Myh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	49,889,783 - 49,914,464 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936595	3,363,975 - 3,388,385 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936595	3,363,974 - 3,416,849 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MYH1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	55,225,590 - 55,249,340 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	12	55,225,581 - 55,251,495 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	57,965,087 - 57,984,759 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103242384
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	9,834,434 - 9,860,744 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666059	11,481,624 - 11,507,924 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Myh1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	46,802,537 - 46,826,361 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Myh1
176 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	55
Count of miRNA genes:	49
Interacting mature miRNAs:	52
Transcripts:	ENSRNOT00000004295
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61441	Btemp1	Thermal response to stress QTL 1	4		body temperature trait (VT:0005535)	core body temperature (CMO:0001036)	10	35893451	64140567	Rat
1549846	Scl47	Serum cholesterol level QTL 47	3.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	51071897	96071897	Rat
152025229	Scl83	Serum cholesterol level QTL 83	4.33		blood cholesterol amount (VT:0000180)		10	36211556	69161158	Rat
1578779	Tcas10	Tongue tumor susceptibility QTL 10	3.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	10	31796281	76796281	Rat
152025227	Bw195	Body weight QTL 195	5.73		body mass (VT:0001259)		10	47489017	69161158	Rat
631564	Apr3	Acute phase response QTL 3	3.9		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	10	15776754	60776754	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	27023535	98502431	Rat
2293669	Bmd33	Bone mineral density QTL 33	4.5	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	10	27443787	72443787	Rat
152025224	Bw193	Body weight QTL 193	6.47		body mass (VT:0001259)		10	52162433	75582749	Rat
631552	Vetf2	Vascular elastic tissue fragility QTL 2	4.5	0.0002	aorta elastic tissue integrity trait (VT:0010556)	artery internal elastic lamina non-tumorous lesion count (CMO:0001913)	10	35509383	91417879	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1250554	64349221	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2293679	Bmd30	Bone mineral density QTL 30	3.5	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	27443787	72443787	Rat
1298078	Stresp5	Stress response QTL 5	2.99	0.00025	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	42546145	107713808	Rat
2298544	Neuinf9	Neuroinflammation QTL 9	4.6		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	10	19939207	64939207	Rat
61332	Eau3	Experimental allergic uveoretinitis QTL 3		0.004	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	18035782	63035782	Rat
61463	Bp12	Blood pressure QTL 12	6.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	41831278	86831278	Rat
1579919	Bp281	Blood pressure QTL 281		0.01	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	50464802	95464802	Rat
8694173	Bw149	Body weight QTL 149	4.38	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	10	44939359	89939359	Rat
2300218	Hpcl2	Hepatic cholesterol level QTL 2			liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	45529164	96099749	Rat
1598852	Anxrr19	Anxiety related response QTL 19	5.07		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	10	18668419	63668419	Rat
1581497	Esta1	Estrogen-induced thymic atrophy QTL 1			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	21833758	61843633	Rat
10450493	Bp382	Blood pressure QTL 382		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	50860288	95860288	Rat
724527	Bp148	Blood pressure QTL 148		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	28950353	73950353	Rat
1358897	Stresp6	Stress response QTL 6	4.17	0.022	blood norepinephrine amount (VT:0005663)	plasma norepinephrine level (CMO:0001010)	10	35893263	64653589	Rat
1331762	Rf40	Renal function QTL 40	3.873		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	10	29800910	64653589	Rat
2300171	Bmd58	Bone mineral density QTL 58	4.9	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	27443787	72443787	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14991535	86964295	Rat
70188	BpQTLcluster1	Blood pressure QTL cluster 1	4.864		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	42823274	87823274	Rat
9589030	Epfw9	Epididymal fat weight QTL 9	19.24	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	10	44939359	89939359	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14991535	107556066	Rat
2293652	Bmd22	Bone mineral density QTL 22	4.9	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	27443787	72443787	Rat
70198	BpQTLcluster9	Blood pressure QTL cluster 9	2.94		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	42823274	87823274	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22931373	91127454	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6660923	73950353	Rat
2306792	Ean4	Experimental allergic neuritis QTL 4	4		nervous system integrity trait (VT:0010566)	IFNG-secreting splenocyte count (CMO:0002122)	10	49495492	94495492	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	52269185	107713808	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	14653541	59653541	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15533012	73695498	Rat
634329	Pia15	Pristane induced arthritis QTL 15	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	24662123	73695339	Rat
70224	Eae3	Experimental allergic encephalomyelitis QTL 3	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	10	27023535	61843633	Rat
2298480	Eau7	Experimental allergic uveoretinitis QTL 7		0.0049	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	35509383	80509383	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29800910	91417879	Rat
2298495	Eae23	Experimental allergic encephalomyelitis QTL 23	16.93		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis duration (CMO:0001424)	10	16175525	61175525	Rat
2313087	Bmd80	Bone mineral density QTL 80	3.2	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	10	20110614	65110614	Rat
631530	Tls3	T-lymphoma susceptibility QTL 3	0	0.0001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	10	27587226	96099902	Rat
2289985	Bp305	Blood pressure QTL 305			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	29076978	74076978	Rat
631532	Cm50	Cardiac mass QTL 50	6.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	18035782	63035782	Rat
8552805	Bw145	Body weight QTL 145	2.2		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	10	43608793	88608793	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2293705	Bmd25	Bone mineral density QTL 25	7.1	0.0001	femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	10	27443787	72443787	Rat
1600371	Mcs21	Mammary carcinoma susceptibility QTL 21	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	29377046	52699134	Rat
631269	Cia22	Collagen induced arthritis QTL 22	8.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40535708	107713808	Rat
1576308	Schws1	Schwannoma susceptibility QTL 1		0.0041	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	10	40535708	107713808	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14991535	107713808	Rat
7207811	Bmd90	Bone mineral density QTL 90	5.2		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	10	49943710	94943710	Rat
1576311	Pia26	Pristane induced arthritis QTL 26			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	31129113	76129113	Rat
631270	Cia23	Collagen induced arthritis QTL 23	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40535708	107713808	Rat
7411614	Foco18	Food consumption QTL 18		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	10	44939359	89939359	Rat
631547	Bp87	Blood pressure QTL 87	4.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	47869129	92869129	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6864618	96620484	Rat
12880050	Am10	Aortic mass QTL 10		0.016	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	10	39503487	84503487	Rat
2292436	Bp310	Blood pressure QTL 310			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	50604677	95604677	Rat
6893342	Cm78	Cardiac mass QTL 78	0.1	0.88	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	35509383	88177745	Rat
2313055	Bw96	Body weight QTL 96	3.6	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	10	20110614	65110614	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	27023535	99451848	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
3	12	24	91	26	29	10	23	10	113	68	10	80	24	45	19	9	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001135158	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085434	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF157005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ872906	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215376	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217422	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217583	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223843	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ224239	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	S68736	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000004236 ⟹ ENSRNOP00000004236

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	10	53,713,938 - 53,738,031 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000004295 ⟹ ENSRNOP00000004295

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	52,384,908 - 52,409,047 (+)	Ensembl
mRatBN7.2 Ensembl	10	51,885,913 - 51,909,699 (+)	Ensembl
Rnor_6.0 Ensembl	10	53,740,841 - 53,764,610 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000045718 ⟹ ENSRNOP00000046362

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	51,923,355 - 51,946,295 (+)	Ensembl
Rnor_6.0 Ensembl	10	53,778,662 - 53,801,603 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000082871 ⟹ ENSRNOP00000072943

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	51,885,913 - 51,946,295 (+)	Ensembl
Rnor_6.0 Ensembl	10	53,781,239 - 53,848,347 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000085582 ⟹ ENSRNOP00000071998

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	52,384,908 - 52,409,047 (+)	Ensembl
mRatBN7.2 Ensembl	10	51,885,913 - 51,909,699 (+)	Ensembl
Rnor_6.0 Ensembl	10	53,713,941 - 53,764,500 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000086599 ⟹ ENSRNOP00000071422

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	10	53,713,938 - 53,848,347 (+)	Ensembl

RefSeq Acc Id:

NM_001135158 ⟹ NP_001128630

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	52,384,912 - 52,408,698 (+)	NCBI
mRatBN7.2	10	51,885,913 - 51,909,699 (+)	NCBI
Dahl_SR_JrHsd	10	55,323,487 - 55,347,273 (+)	NCBI
Lyon_Normotensive	10	55,983,577 - 56,007,346 (+)	NCBI
Lyon_Hypertensive	10	57,648,472 - 57,672,258 (+)	NCBI
F344_StmMcwi	10	57,567,815 - 57,591,584 (+)	NCBI
Rnor_6.0	10	53,740,841 - 53,764,610 (+)	NCBI
Rnor_5.0	10	53,493,997 - 53,517,766 (+)	NCBI
RGSC_v3.4	10	53,894,388 - 53,917,948 (+)	RGD
Celera	10	51,068,765 - 51,092,552 (+)	RGD

Sequence:

show sequence

TCTTTCCTCATAAAGCTTCAAGTTCAGACCCACGGTCGAAGTTGCATCCCTAAAGGCAGACTCT
CCCACTGGGCTGCCCCCAATAGCCCGCAGCCATGAGTTCCGACGCCGAGATGGCCGTTTTCGGG
GAGGCTGCTCCTTACCTCCGGAAGTCTGAAAAGGAGCGAATCGAGGCTCAGAACAAGCCTTTTG
ATGCCAAGTCATCCGTGTTTGTGGTGGATGCTAAGGAGTCTTTTGTAAAAGCAACGGTGCAGAG
CAGGGAAGGGGGGAAGGTGACAGCCAAGACCGAAGGTGGCGCTACTGTAACAGTAAAAGATGAT
CAAGTCTTCCCCATGAACCCTCCCAAGTACGACAAGATCGAGGACATGGCCATGATGACCCACC
TCCACGAGCCTGCTGTGCTGTACAACCTCAAAGAGCGTTACGCAGCCTGGATGATCTACACCTA
CTCGGGCCTGTTCTGTGTCACTGTCAACCCCTACAAGTGGCTGCCAGTGTATAATGCAGAGGTG
GTGGCAGCTTACCGAGGCAAAAAGCGCCAGGAGGCCCCGCCCCACATCTTCTCTATCTCTGACA
ACGCCTACCAGTTCATGTTGACAGATCGGGAGAACCAGTCTATTTTGATCACCGGAGAATCTGG
GGCTGGGAAGACTGTGAACACGAAGCGTGTCATCCAGTACTTTGCAACAATTGCAGTCACTGGG
GAGAAGAAGAAGGAGGAAGCACCTTCTGGCAAAATGCAGGGGACCCTGGAGGATCAAATCATCA
GTGCCAATCCTCTGCTGGAAGCCTTCGGGAATGCCAAGACCGTGAGGAATGACAACTCCTCTCG
CTTTGGTAAATTCATCAGGATCCACTTTGGTACCACAGGGAAGCTGGCTTCTGCTGATATTGAA
ACATATCTTCTGGAGAAGTCTAGAGTCACCTTCCAGCTAAAAGCTGAGAGAAGCTACCATATTT
TTTACCAGATCATGTCTAACAAGAAGCCAGATCTAATTGAAATGCTCCTGATCACCACCAACCC
ATACGACTACGCCTTTGTCAGTCAGGGGGAGATCACAGTGCCCAGCATTGATGACCAAGAAGAG
TTGATGGCCACAGATAGTGCCATTGATATTCTGGGCTTCACTTCTGATGAAAGAGTCTCCATCT
ATAAGCTCACGGGGGCTGTGATGCATTATGGGAACATGAAGTTCAAGCAGAAGCAACGTGAGGA
GCAGGCTGAGCCGGATGGCACGGAAGTGGCTGACAAGGCTGCCTATCTCCAAAATCTGAACTCT
GCTGACCTGCTCAAAGCCCTGTGTTACCCCAGGGTCAAGGTCGGCAATGAGTATGTCACCAAAG
GCCAGACTGTGCAGCAGGTGTACAACGCTGTGGGTGCCCTGGCCAAAGCTGTCTACGAGAAGAT
GTTCCTTTGGATGGTCACCCGCATCAACCAGCAGCTGGACACCAAGCAGCCCAGGCAGTACTTC
ATCGGGGTCTTGGACATCGCTGGCTTTGAGATCTTTGATTTCAACAGCCTGGAGCAGCTGTGCA
TCAACTTCACCAACGAGAAACTGCAACAGTTTTTCAACCACCACATGTTCGTGCTGGAGCAGGA
GGAGTACAAGAAGGAAGGCATCGAGTGGGAGTTCATCGACTTCGGGATGGACCTGGCGGCCTGC
ATCGAGCTCATCGAGAAGCCAATGGGCATCTTCTCCATCCTGGAAGAGGAGTGCATGTTCCCCA
AAGCGACAGACACCTCCTTCAAGAACAAGCTGTATGAACAGCATCTTGGAAAGTCCAACAACTT
CCAGAAGCCCAAACCCGCCAAAGGCAAGGTTGAGGCCCACTTCTCTCTGGTGCACTATGCCGGC
ACCGTTGACTACAACATCGCTGGCTGGCTGGACAAGAACAAGGACCCCCTGAATGAGACCGTGG
TGGGGCTGTACCAGAAGTCTTCAATGAAAACTCTGGCTTACCTCTTCTCTGGGGCAGCAGCTGC
TGCTGAAGCAGAGTCTGGTGGCGGTGGTGGAAAGAAAGGGGCAAAGAAGAAGGGTTCTTCCTTC
CAGACTGTGTCAGCTCTCTTCAGGGAGAACCTGAATAAGCTGATGACCAATCTGAGGAGCACTC
ACCCCCACTTTGTCCGGTGCATCATCCCCAATGAGACTAAGACGCCTGGTGCCATGGAGCACGA
ACTGGTCCTGCACCAGCTGAGGTGTAACGGGGTACTGGAAGGCATCCGCATCTGCAGGAAGGGG
TTCCCCAGCAGGATCCTCTACGCAGACTTCAAGCAGAGATACAAGGTGTTAAATGCAAGTGCCA
TCCCCGAGGGACAATTCATCGATAGCAAGAAGGCTTCTGAGAAGCTCCTTGGCTCCATCGACAT
TGACCACACTCAGTATAAGTTTGGTCACACCAAGGTCTTTTTCAAAGCTGGTCTTCTGGGGCTC
CTAGAGGAGATGAGAGATGACAAGTTGGCCCAGCTGATTACCCGGACGCAGGCCATGTGCCGAG
GGTACTTGGCAAGAGTGGAGTACCAGAAGATGGTGGAGCGAAGAGAGTCCATCTTCTGCATCCA
GTACAACGTCCGAGCCTTCATGAATGTGAAACACTGGCCCTGGATGAAGCTGTATTTCAAGATC
AAACCTCTCTTGAAGAGTGCCGAGACAGAGAAGGAGATGGCCAACATGAAGGAAGAGTTTGAAA
AAACTAAAGAAAACCTTGCAAAGGCAGAGGCCAAAAGGAAAGAGCTAGAAGAAAAGATGGTGGC
TCTGATGCAGGAGAAAAATGACCTGCAGCTCCAAGTTCAGTCTGAAGCAGACAGCTTGGCTGAT
GCTGAGGAAAGATGCGACCAGCTGATCAAAACCAAAATCCAGCTGGAGGCCAAAATCAAAGAGG
TGACTGAGAGAGCAGAGGATGAGGAAGAGATCAACGCCGAGCTCACCGCCAAGAAGAGGAAGCT
GGAGGACGAGTGCTCAGAGCTGAAGAAAGACATCGATGACCTTGAGCTGACACTGGCCAAGGTT
GAGAAGGAGAAGCACGCCACGGAGAACAAGGTGAAAAACCTCACAGAGGAGATGGCGGGCCTGG
ACGAAACCATCGCCAAGCTGACCAAGGAGAAGAAGGCCTTGCAGGAGGCCCACCAGCAGACCCT
GGATGACCTGCAGGCAGAGGAGGACAAAGTCAACACCCTGACCAAAGCCAAAATCAAGCTGGAA
CAGCAAGTGGATGACCTTGAAGGCTCTCTGGAACAAGAAAAGAAAATCCGGATGGATCTTGAAA
GAGCCAAGAGGAAACTCGAGGGGGACCTAAAACTGGCCCAAGAGTCCACAATGGACGTAGAAAA
TGACAAACAGCAGCTCGATGAGAAACTCAAAAAGAAAGAGTTTGAAATGAGCAACCTGCAGAGC
AAGATCGAGGATGAACAGGCCCTCGGCATGCAGCTGCAGAAGAAGATCAAGGAGTTGCAGGCTC
GCATTGAGGAGCTGGAGGAGGAAATCGAGGCAGAGCGGGCCTCCAGGGCCAAAGCAGAGAAGCA
GCGCTCTGACCTCTCCCGGGAACTGGAGGAGATCAGCGAGCGGCTGGAAGAAGCCGGCGGGGCC
ACTTCAGCCCAGATCGAGATGAACAAGAAGAGAGAGGCCGAGTTCCAGAAAATGCGCAGGGACC
TGGAGGAGGCCACCCTGCAGCACGAAGCCACAGCAGCCACCCTGAGGAAGAAGCACGCGGACAG
CGTGGCTGAGCTCGGGGAGCAGATCGACAACCTGCAGCGGGTGAAGCAGAAGCTGGAGAAGGAG
AAGAGCGAGATGAAGATGGAGATCGACGACCTCGCTAGCAACATGGAGGTCATTTCCAAATCCA
AGGGAAACCTTGAGAAGATGTGCCGCACTCTGGAGGACCAGGTGAGCGAGCTGAAGACCAAGGA
GGAGGAGCAGCAGCGGCTCATCAACGAGCTGACCGCGCAGAGGGGGCGTCTGCAGACAGAGTCA
GGTGAATATTCACGCCAGCTGGATGAAAAGGATTCATTAGTTTCTCAGCTCTCCAGGGGCAAAC
AGGCATTCACTCAACAGATTGAGGAGCTGAAGAGGCAGCTTGAAGAGGAAGTAAAGGCCAAGAG
TGCCCTGGCTCATGCTCTTCAGTCCTCCCGCCATGACTGTGACCTTCTGCGGGAACAGTATGAA
GAAGAACAGGAAGCCAAGGCTGAACTGCAGAGGGCCATGTCCAAGGCCAACAGTGAAGTGGCCC
AGTGGAGGACGAAATATGAGACGGATGCCATCCAGCGCACGGAAGAACTGGAGGAGGCCAAGAA
GAAGCTGGCTCAGCGTCTGCAGGATGCTGAGGAGCACGTAGAAGCCGTGAACGCCAAGTGTGCT
TCCCTGGAGAAGACGAAGCAGAGGCTGCAGAATGAGGTGGAGGACCTCATGATTGATGTGGAGA
GGACCAACGCTGCCTGTGCCGCCCTGGACAAGAAGCAGAGAAACTTCGACAAGATCCTGGCAGA
ATGGAAACAGAAGTATGAGGAAACGCATGCTGAACTTGAAGCCTCCCAGAAGGAGTCCCGCTCT
CTCAGCACAGAGTTGTTCAAGATTAAGAATGCTTATGAGGAATCTTTAGACCAACTTGAAACCT
TGAAAAGGGAAAATAAGAATTTGCAACAGGAGATCTCTGACCTCACTGAACAGATTGCAGAAGG
AGGGAAACGTATCCATGAACTGGAAAAAATAAAGAAGCAAATTGAGCAAGAAAAATCCGAGCTC
CAGGCTGCTTTAGAGGAAGCAGAGGCATCTCTGGAGCACGAGGAGGGAAAGATCCTGCGCATCC
AGCTGGAGCTGAACCAAGTCAAGTCTGAGATCGACAGGAAGATTGCTGAGAAGGATGAGGAAAT
TGACCAGCTGAAGAGAAACCACATTCGAGTCGTGGAGTCCATGCAGAGCACGCTGGATGCCGAG
ATCAGGAGCAGGAATGACGCCATCAGGATCAAGAAGAAGATGGAGGGAGACCTCAATGAGATGG
AAATCCAGCTGAACCACTCCAACCGCATGGCTGCTGAGGCCCTGAGAAACTACAGGAACACCCA
AGGCATCCTCAAGGACACCCAGTTGCACCTGGATGACGCTCTCCGGGGCCAGGAGGACCTGAAG
GAGCAGCTGGCCATGGTGGAGCGCAGAGCCAACCTGCTGCAGGCTGAGATCGAGGAGCTGCGGG
CCACTCTGGAGCAGACTGAGAGGAGCAGGAAGATTGCAGAGCAGGAACTGCTGGACGCCAGTGA
GCGCGTGCAGCTCCTCCACACCCAGAACACCAGCCTCATCAACACCAAGAAGAAGCTGGAGACA
GACATTTCCCAGATCCAGGGAGAGATGGAGGACATCGTCCAGGAAGCCCGCAATGCAGAAGAGA
AGGCCAAGAAAGCCATCACTGACGCCGCCATGATGGCGGAGGAGCTGAAGAAGGAGCAGGACAC
CAGCGCCCATCTGGAGCGGATGAAGAAGAACCTGGAGCAGACGGTGAAGGACCTGCAGCACCGT
CTGGACGAGGCTGAGCAGCTGGCGCTGAAGGGCGGCAAGAAGCAGATCCAGAAACTGGAGGCCA
GGGTCCGTGAACTTGAAGGAGAAGTTGAAAACGAACAGAAGCGCAATGTTGAAGCTATCAAGGG
TCTGCGCAAACATGAGAGAAGAGTGAAAGAACTCACTTACCAAACTGAGGAAGACCGCAAGAAC
GTTCTCAGGCTCCAGGACCTTGTGGACAAACTGCAATCAAAGGTCAAAGCATACAAGAGACAAG
CCGAGGAAGCGGAGGAACAATCCAACGTCAACCTGGCCAAGTTCCGCAAGATCCAGCACGAGCT
GGAGGAAGCCGAGGAGCGGGCTGACATCGCCGAGTCCCAGGTCAACAAGCTGCGGGTGAAGAGC
CGCGAGGTTCACACCAAAATCATAAGCGAAGAGTGATCGATCCAAAGCAGGAAAGTGACCAAAG
AGATGAGCAAAATGTGAAGATCTTTGTCACTCCATTTTGTACTTACGACTTTGGGAGATAAAAA
ATTTATCTGCCAAGA

hide sequence

RefSeq Acc Id:

XM_039085434 ⟹ XP_038941362

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	52,384,810 - 52,408,696 (+)	NCBI
mRatBN7.2	10	51,886,199 - 51,909,592 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001128630	(Get FASTA)	NCBI Sequence Viewer
	XP_038941362	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB29713	(Get FASTA)	NCBI Sequence Viewer
	AAD51613	(Get FASTA)	NCBI Sequence Viewer
	ABI34117	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000004295
	ENSRNOP00000004295.7
	ENSRNOP00000071998.2

RefSeq Acc Id:

NP_001128630 ⟸ NM_001135158

- UniProtKB:

F1LRV9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSSDAEMAVFGEAAPYLRKSEKERIEAQNKPFDAKSSVFVVDAKESFVKATVQSREGGKVTAKT
EGGATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNP
YKWLPVYNAEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRV
IQYFATIAVTGEKKKEEAPSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFG
TTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGE
ITVPSIDDQEELMATDSAIDILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVA
DKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQ
QLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWE
FIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKV
EAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSMKTLAYLFSGAAAAAEAESGGGGG
KKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNG
VLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHT
KVFFKAGLLGLLEEMRDDKLAQLITRTQAMCRGYLARVEYQKMVERRESIFCIQYNVRAFMNVK
HWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKENLAKAEAKRKELEEKMVALMQEKNDLQL
QVQSEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD
IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV
NTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDVENDKQQLDEKLK
KKEFEMSNLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE
ISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDN
LQRVKQKLEKEKSEMKMEIDDLASNMEVISKSKGNLEKMCRTLEDQVSELKTKEEEQQRLINEL
TAQRGRLQTESGEYSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEVKAKSALAHALQSSR
HDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAE
EHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKYEETHA
ELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKI
KKQIEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHIRV
VESMQSTLDAEIRSRNDAIRIKKKMEGDLNEMEIQLNHSNRMAAEALRNYRNTQGILKDTQLHL
DDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNT
SLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN
LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNVEAIKGLRKHERRVKE
LTYQTEEDRKNVLRLQDLVDKLQSKVKAYKRQAEEAEEQSNVNLAKFRKIQHELEEAEERADIA
ESQVNKLRVKSREVHTKIISEE

hide sequence

Ensembl Acc Id:

ENSRNOP00000072943 ⟸ ENSRNOT00000082871

Ensembl Acc Id:

ENSRNOP00000046362 ⟸ ENSRNOT00000045718

Ensembl Acc Id:

ENSRNOP00000004295 ⟸ ENSRNOT00000004295

Ensembl Acc Id:

ENSRNOP00000004236 ⟸ ENSRNOT00000004236

Ensembl Acc Id:

ENSRNOP00000071998 ⟸ ENSRNOT00000085582

Ensembl Acc Id:

ENSRNOP00000071422 ⟸ ENSRNOT00000086599

RefSeq Acc Id:	XP_038941362 ⟸ XM_039085434
- Peptide Label:	isoform X1
- UniProtKB:	F1LRV9 (UniProtKB/TrEMBL)

Protein Domains

Myosin motor Myosin N-terminal SH3-like

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697292

Promoter ID:

EPDNEW_R7815

Type:

multiple initiation site

Name:

Myh4_1

Description:

myosin heavy chain 4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R7816

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	53,740,840 - 53,740,900	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:735061	AgrOrtholog
BioCyc Gene	G2FUF-24656	BioCyc
Ensembl Genes	ENSRNOG00000049695	Ensembl
	ENSRNOG00000083924	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000004295	ENTREZGENE
	ENSRNOT00000004295.8	UniProtKB/TrEMBL
	ENSRNOT00000085582.3	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.820	UniProtKB/TrEMBL
	1.20.5.340	UniProtKB/TrEMBL
	1.20.5.370	UniProtKB/TrEMBL
	1.20.5.4820	UniProtKB/TrEMBL
	1.20.58.530	UniProtKB/TrEMBL
	2.30.30.360	UniProtKB/TrEMBL
	3.40.850.10	UniProtKB/TrEMBL
	6.10.250.2420	UniProtKB/TrEMBL
	Myosin VI head, motor domain, U50 subdomain	UniProtKB/TrEMBL
InterPro	IQ_motif_EF-hand-BS	UniProtKB/TrEMBL
	Kinesin_motor_dom_sf	UniProtKB/TrEMBL
	Myosin_head_motor_dom	UniProtKB/TrEMBL
	Myosin_N	UniProtKB/TrEMBL
	Myosin_S1_N	UniProtKB/TrEMBL
	Myosin_tail	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	XRCC4-like_C	UniProtKB/TrEMBL
NCBI Gene	287408	ENTREZGENE
PANTHER	MYOSIN HEAVY CHAIN, NON-MUSCLE	UniProtKB/TrEMBL
	MYOSIN-1	UniProtKB/TrEMBL
Pfam	Myosin_head	UniProtKB/TrEMBL
	Myosin_N	UniProtKB/TrEMBL
	Myosin_tail_1	UniProtKB/TrEMBL
PhenoGen	Myh1	PhenoGen
PRINTS	MYOSINHEAVY	UniProtKB/TrEMBL
PROSITE	MYOSIN_MOTOR	UniProtKB/TrEMBL
	PS50096	UniProtKB/TrEMBL
	SH3_LIKE	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000049695	RatGTEx
	ENSRNOG00000083924	RatGTEx
SMART	MYSc	UniProtKB/TrEMBL
	SM00015	UniProtKB/TrEMBL
Superfamily-SCOP	Myosin rod fragments	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
UniProt	A0A0G2K1V4_RAT	UniProtKB/TrEMBL
	F1LRV9	ENTREZGENE, UniProtKB/TrEMBL
	Q0GC39_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-06-29	Myh1	myosin heavy chain 1	Myh1	myosin, heavy chain 1, skeletal muscle, adult	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-10-05	Myh1	myosin, heavy chain 1, skeletal muscle, adult	Myh1	myosin, heavy polypeptide 1, skeletal muscle, adult	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Myh1	myosin, heavy polypeptide 1, skeletal muscle, adult		type 2X myosin heavy chain	Name updated	1299863	APPROVED
2004-09-10	Myh1	type 2X myosin heavy chain	MYHC		Symbol and Name updated	1299863	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	highly expressed in diaphram	1302818
gene_other	speed of shortening of muscle fibers expressing 2X-MyHC is intermediate between that of fibers expressing 2A-MyHC and 2B-MyHC	1302818

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - KEGG (archival)