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Gene: Zfp483 (zinc finger protein 483) Rattus norvegicus

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Symbol:

Zfp483 (Ensembl: Zkscan16)

Name:

zinc finger protein 483

RGD ID:

727958

Description:

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF483 (zinc finger protein 483); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

HIT-10; Hit10; zinc finger protein HIT-10; zinc finger with KRAB and SCAN domains 16; Zkscan16; Znf483

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZNF483 (zinc finger protein 483)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Zkscan16 (zinc finger with KRAB and SCAN domains 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Znf483 (zinc finger protein 483)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ZNF483 (zinc finger protein 483)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ZNF483 (zinc finger protein 483)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	LOC101956379 (uncharacterized LOC101956379)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ZNF483 (zinc finger protein 483)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZNF483 (zinc finger protein 483)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Znf483 (zinc finger protein 483)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Znf483 (zinc finger protein 483)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ZNF483 (zinc finger protein 483)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Zkscan16 (zinc finger with KRAB and SCAN domains 16)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-255f4.1	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Drosophila melanogaster (fruit fly):	CG5245	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	LOC100486793	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	LOC101732786	Alliance	DIOPT (Ensembl Compara\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	78,558,213 - 78,575,559 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	78,558,304 - 78,575,552 (+)	Ensembl				GRCr8
mRatBN7.2	5	73,763,201 - 73,780,511 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	73,763,179 - 73,776,223 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	75,664,552 - 75,681,799 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	77,486,169 - 77,503,412 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	77,458,327 - 77,475,570 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	76,090,015 - 76,103,051 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	76,092,287 - 76,102,590 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	80,234,454 - 80,247,490 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	76,990,071 - 77,003,107 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	72,586,427 - 72,599,341 (+)	NCBI		Celera
RGSC_v3.1	5	76,995,183 - 77,008,220 (+)	NCBI
Cytogenetic Map	5	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

ammonium chloride (EXP)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

cisplatin (ISO)

cocaine (EXP)

crocidolite asbestos (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

dorsomorphin (ISO)

flavonoids (EXP)

hydroquinone O-beta-D-glucopyranoside (ISO)

kojic acid (ISO)

nickel atom (ISO)

panobinostat (ISO)

paracetamol (ISO)

paraquat (EXP)

phenylmercury acetate (ISO)

potassium chromate (ISO)

SB 431542 (ISO)

serpentine asbestos (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

regulation of DNA-templated transcription (IEA)

Cellular Component

nucleus (IEA)

Molecular Function

DNA binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

sequence-specific DNA binding (IEA)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	NCBI rat LocusLink and RefSeq merged data October 15, 2003	NCBI rat LocusLink and RefSeq merged data October 15, 2003
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Information Derived from GenBank Report	RGD, Sept. 2003

Genomics

Comparative Map Data

Zfp483
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	78,558,213 - 78,575,559 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	78,558,304 - 78,575,552 (+)	Ensembl				GRCr8
mRatBN7.2	5	73,763,201 - 73,780,511 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	73,763,179 - 73,776,223 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	75,664,552 - 75,681,799 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	77,486,169 - 77,503,412 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	77,458,327 - 77,475,570 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	76,090,015 - 76,103,051 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	76,092,287 - 76,102,590 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	80,234,454 - 80,247,490 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	76,990,071 - 77,003,107 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	72,586,427 - 72,599,341 (+)	NCBI		Celera
RGSC_v3.1	5	76,995,183 - 77,008,220 (+)	NCBI
Cytogenetic Map	5	q24	NCBI

ZNF483
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	111,525,179 - 111,578,136 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	111,525,054 - 111,577,844 (+)	Ensembl			hg38	GRCh38
GRCh37	9	114,287,459 - 114,340,416 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	113,327,260 - 113,379,945 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	9	84,786,545 - 84,839,198 (+)	NCBI		Celera
Cytogenetic Map	9	q31.3	NCBI
HuRef	9	83,886,547 - 83,938,538 (+)	NCBI		HuRef
CHM1_1	9	114,433,891 - 114,486,596 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	123,696,561 - 123,749,515 (+)	NCBI		T2T-CHM13v2.0

Zkscan16
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	58,943,568 - 58,962,624 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	58,943,628 - 58,958,355 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	58,943,568 - 58,962,624 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	58,943,628 - 58,958,355 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	58,987,516 - 59,003,647 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	58,958,999 - 58,970,778 (+)	NCBI		MGSCv36	mm8
Celera	4	58,856,697 - 58,871,392 (+)	NCBI		Celera
Cytogenetic Map	4	B3	NCBI
cM Map	4	32.36	NCBI

Znf483
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	15,741,230 - 15,755,061 (-)	Ensembl
ChiLan1.0	NW_004955419	15,741,368 - 15,775,100 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZNF483
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	27,844,361 - 27,897,802 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	27,846,723 - 27,900,164 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	82,662,886 - 82,714,448 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	110,824,701 - 110,875,895 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	110,826,949 - 110,875,507 (+)	Ensembl			panPan2	panpan1.1

ZNF483
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	66,165,805 - 66,179,794 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	66,166,676 - 66,177,259 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	64,576,593 - 64,590,559 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	67,298,597 - 67,312,558 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	67,298,675 - 67,311,655 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	65,816,513 - 65,833,692 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	65,839,862 - 65,853,565 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	66,529,162 - 66,543,128 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

LOC101956379
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	181,483,384 - 181,485,714 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936559	1,770,475 - 1,783,016 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZNF483
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	252,342,219 - 252,373,375 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	252,342,621 - 252,356,014 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ZNF483
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	28,025,828 - 28,042,018 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	28,025,952 - 28,044,244 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666035	14,734,313 - 14,759,741 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Znf483
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	6,055 - 14,917 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624758	2,472 - 19,700 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Znf483
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	92,479,354 - 92,492,332 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Zfp483
79 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	91
Count of miRNA genes:	75
Interacting mature miRNAs:	81
Transcripts:	ENSRNOT00000020207
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298067	Scl15	Serum cholesterol level QTL 15	4.8	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	38011670	83011670	Rat
1300115	Hrtrt7	Heart rate QTL 7	2.76		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	5	52665372	94894052	Rat
1357396	Bw44	Body weight QTL 44	4.19		body mass (VT:0001259)	body weight (CMO:0000012)	5	73779642	118779642	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	44924861	153890773	Rat
6907115	Mcs29	Mammary carcinoma susceptibility QTL 29			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	38004331	83004331	Rat
61380	Edpm5	Estrogen-dependent pituitary mass QTL 5	4.5	0.92	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	5	73779642	103472210	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	38207390	136631402	Rat
1358353	Srcrtb2	Stress Responsive Cort Basal QTL 2	3.48	0.003	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	23671493	79046465	Rat
61386	Bp49	Blood pressure QTL 49	16.6		cerebrum integrity trait (VT:0010549)	brain infarction volume (CMO:0001013)	5	65089051	103648916	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	48523123	134369373	Rat
2302381	Bw84	Body weight QTL 84	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	73779642	118779642	Rat
1357402	Bw46	Body weight QTL 46	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	73779642	118779642	Rat
1598807	Glom12	Glomerulus QTL 12	2.7		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	38011670	83011670	Rat
1302786	Kidm8	Kidney mass QTL 8	28.15		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	38011670	83011670	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	65089051	166764498	Rat
1331782	Rf36	Renal function QTL 36	3.296		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	39019942	102105896	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	51657967	166600247	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	39985948	84985948	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	6922282	81330203	Rat
7394708	Emca11	Estrogen-induced mammary cancer QTL 11			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	73176602	118176602	Rat
1576317	Eutr2	Estrogen induced uterine response QTL 2		0.01	uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	39526924	84526924	Rat
1331773	Scl26	Serum cholesterol level QTL 26	3.065		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	48523123	91770353	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	69474415	114474415	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	60601597	137492949	Rat
1331771	Rf35	Renal function QTL 35	4.36965		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	91770353	Rat
61359	Eaex	Experimental allergic encephalomyelitis QTL x	3		nervous system integrity trait (VT:0010566)	post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)	5	60511627	105511627	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	74335621	156302135	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	36460764	136631402	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	64589016	109589016	Rat
2290005	Mcs24	Mammary carcinoma susceptibility QTL 24			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	69835120	114835120	Rat
1331756	Rf34	Renal function QTL 34	4.16275		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	5	10019064	87027358	Rat
2306971	Anxrr21	Anxiety related response QTL 21	9.47		fear/anxiety-related behavior trait (VT:1000241)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	5	70969494	136328156	Rat
2316954	Rf57	Renal function QTL 57	0		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	5	64589016	93503770	Rat
2312671	Scl64	Serum cholesterol level QTL 64		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	73779642	118779642	Rat
2316959	Gluco59	Glucose level QTL 59	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	56546393	101546393	Rat
2316957	Pur21	Proteinuria QTL 21	6.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	5	64589016	91762830	Rat

Markers in Region

D5Got232

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	73,773,218 - 73,773,355 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	76,099,960 - 76,100,096	NCBI	Rnor6.0
Rnor_5.0	5	80,244,399 - 80,244,535	UniSTS	Rnor5.0
RGSC_v3.4	5	77,000,016 - 77,000,152	UniSTS	RGSC3.4
Celera	5	72,596,360 - 72,596,498	UniSTS
Cytogenetic Map	5	q24	UniSTS

BF390756

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	73,766,441 - 73,766,592 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	76,093,185 - 76,093,335	NCBI	Rnor6.0
Rnor_5.0	5	80,237,624 - 80,237,774	UniSTS	Rnor5.0
RGSC_v3.4	5	76,993,241 - 76,993,391	UniSTS	RGSC3.4
Celera	5	72,589,597 - 72,589,747	UniSTS
RH 3.4 Map	5	506.2	UniSTS
Cytogenetic Map	5	q24	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
12	9	65	164	73	72	41	44	41	6	271	138	11	143	72	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_133422	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109216	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109217	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109218	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109219	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC110824	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF277901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000020207 ⟹ ENSRNOP00000020207

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	73,763,179 - 73,776,223 (+)	Ensembl
Rnor_6.0 Ensembl	5	76,092,287 - 76,102,590 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000167599 ⟹ ENSRNOP00000103543

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	78,558,304 - 78,575,552 (+)	Ensembl

RefSeq Acc Id:

NM_133422 ⟹ NP_596913

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	78,558,322 - 78,575,559 (+)	NCBI
mRatBN7.2	5	73,763,272 - 73,780,511 (+)	NCBI
Rnor_6.0	5	76,090,015 - 76,103,051 (+)	NCBI
Rnor_5.0	5	80,234,454 - 80,247,490 (+)	NCBI
RGSC_v3.4	5	76,990,071 - 77,003,107 (+)	RGD
Celera	5	72,586,427 - 72,599,341 (+)	RGD

Sequence:

show sequence

GAATTCGGCACGAGGCGGTGCAGCTGGCTGCGGATGTTGGTGCAGTTCCTTCAAGACTGTACGT
TGGATTCCTGGAGCCCTTGGTAGTTTTCCGTGCACAGATAGCACCTGTTAGCAGATCAGACTGA
TTCTCAGTGTAAAGAGGACTGGATTCCTGGTGCTGATACAATGCAAGCGTTAGTGCCCTCAGAC
ATGATGGCAGGCATCTCCCCAGACCCTTCAGCTTTGCCTCTGAGTGAACAAAGCAGGGCCCCCA
GAGTGGATACTCTGAGGGGCCAAGAAAGTATGTTAAGAGAGGACCTGGAGTCTTTCAGGCAGAA
GTTCAGGTGGTTTTGTTACTCACAGGAAGAAGGACCCAGAAAAACCCTGAATCAACTCTGGGAA
CTCTGCAAGCAGTGGCTGAGACCAGACATTCACACCAAAGAGCAGATCTTAGAGCTGTTAGTGT
TTGAGCAGTTCCTGAGGGTTTTGCCTGGAGAGATGAGGATTTGGGTGAATTCTCAGCATCCTGA
GAGTAGTGTGGAGGTGGTGACCCTGGTAGAAGATTTGAACCAAACCCTTGAAGAAAAGGAAGAT
CGTAACACTCAGGCTCCTGATGTTTGCAAAGAGGAAGATTTGGGAGAAGAAGCGATGGCGGCAG
CTCCTCCAAGTGCTGAGGTGGCGGCTCCTCCACGTGCTGAGCCACGTGAAGCTGTAACATTTGA
GGACGTGTCTGTGGACTTTACCAGAGGAGAGTGGAAGCTGCTGGAACCTTCTCAAAGGGAGCTA
TATAAGGAGGTGCTGCTGGAGAACTTAGGGAGCCTAGAAGTTCTGGGCTCTCCTGTTTCCAAAT
TCGACTTGATTTCCCATCTGAAGTGGGTTAAGTTGCCAAGGGTACTGGAAAAAGAACTCTCAAA
AGACCCTAGACCAGGAGAGTCGGTAAAAGAGAGTGAGTCTAGAAGTGAATTGGATGCTTTTATG
GAAGAGTTGACTTTAGAGAAAACAGTAGAGTACTGCTTCAGCGGCGGTGGCTATGGCCTGAAGA
CAGAATTCCAGAAGCGGCTCGGCAAACCCGAGAAAGACCATGGCAGGCGGAAGAGCCATGAGAG
TAAGGAGGCTGAGTCAGGAGAGACGACCTCTGAGAAGAATGTCAAGCAAACTTCCGCCATGCTC
AAACATCGGAAAGCCCTCTTAACAAAGACGTCTCAGAGGTCTAAGGAAGGCAAGAAACCCTTCA
GCTTTCATTCAGCTCTTGTGAACCGCAGAGAGCTCAGTGGGGGGAAGTCCAGGAAATGCAGTGA
TCGTGAGAAGGACCCACATCGCCCTTTGTCTCCTACTGAACGTAAGAGACATCCTAAAATTGGT
TCGCTGCGTAAGACCGAGAAGTGTAGTAAGTGCGGGGTAGACTTTACTCGAATCCTAGGGTGTG
TTGAAAGCTCTCAGTGTGAAAAATGCAGGAAGAATTTATTTCAAGATGAAACCTCAAGTAAGGA
CCAGGAAGCCGACACTGAAGAGCCCCGTAAGTGTAAGAAGTGCGGGAAAGCCTTGGAGTACGGT
TCAAAACGCTCCGTGTGTGTTGAATGTAGAAATGCTCACAAAGCTAGCCCCTCCCTCAAGCCAC
AAGGCAAAACTGACAGGAGAAAGAAGTCTTATAAGTGTGATGAGTGTGGGAAGCGCTTTGCCGA
GGAGAATGATTTCAGTCAGCATCAGAGAACCCATACCAGAGAGAAGCCCTATGTGTGTAAACAC
TGTGGGAGAGCTTTCAGCGACAACTCGTCGTTTTGTCAGCACCAGAGAATTCACACCGGAGAGA
AACCATATACGTGCAAGGAGTGTGGGAAATCCTTCACTCACAGTTCTTCTCTTTCAAAACATCA
GAGGATACACACCGGAGAGAAGCCCTATAAGTGTAAGGAGTGTGGGAAAGCCTTTAGGCAGAAT
TCTTGCCTTACCCGACATCAGAAGATCCACACCGGAGAGAAACCATTCTTGTGTAAGGAGTGCG
GGTTGTCGTTTCGCCTCTTTAGCAGCATCATGTATCATCAAAGACTCCATAAGGGAGAAAAACC
CTACAAATGCCCTCACTGTGAGAAGGGTTTCCCCTCTCATTCCCGCCTCAGTCGGCATTTGAGA
ATCCACACCGGTGCGAAACCATACAAGTGTAAAGAGTGTGGGAAAACTTTCAGGCAGAGCTCGT
CGCTTAATTTGCACATCCGAACCCACACTGGAGAGAAGCCCTACAAATGCAATTACTGTGGCGC
GGCCTTTACCCGCAGCACGATCCTCGTTGAACATGTCAAAACTCACACTAGAGTAAAGTACGAC
TGTAAGAAGTGTGGTAAGAGCTTTAAAAGCCGCTCAGCCAACCTTAGACATCACTGTACACTGT
AATCCTGGGACCGGGGGAGGGTGGAGGGGAGTTTAGTTCAGATTGTGCCCTTATTTAAAAGCTC
GAATCGGAAACGACCCACCGCATCGATGAGAAGCTTTTCGCCTTCAGTGAGGTCCCAAACCGGG
ACTTCTTCCCCATTGGTCCCTCTTCTTGAGGGCGGTCAGTTTCGATTAGACCTGGTAAAGTCAC
GTTGACGCGGAGAAAGCGTGTGAAGTGACATGATTCTGAGAAGACAAACGTAAGTTCAAAAAAC
ACTTTCCTTAAGGAATTCTCCCTTTGGTCTCCCTTTCACTGCCGTACCTGGGAAAGAACATGAC
GGGACTCCTTAACCTGGGTTCCATCCCAGTTTGCCAACCAACCATGTGTCACCTTCAACAAGTC
ACGTGGACCTTCTGAAGGCTAAGTTTCTTTACCAGAGGAGTTGAAGAGATGAAGACTTCTCAGT
TCTCTTCTTATCTG

hide sequence

RefSeq Acc Id:

XM_039109213 ⟹ XP_038965141

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	78,558,213 - 78,575,559 (+)	NCBI
mRatBN7.2	5	73,763,201 - 73,780,511 (+)	NCBI

RefSeq Acc Id:

XM_039109214 ⟹ XP_038965142

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	78,558,591 - 78,575,559 (+)	NCBI
mRatBN7.2	5	73,763,540 - 73,780,511 (+)	NCBI

RefSeq Acc Id:

XM_039109216 ⟹ XP_038965144

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	78,558,309 - 78,575,559 (+)	NCBI
mRatBN7.2	5	73,763,309 - 73,780,511 (+)	NCBI

RefSeq Acc Id:

XM_039109217 ⟹ XP_038965145

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	78,558,278 - 78,575,559 (+)	NCBI
mRatBN7.2	5	73,763,309 - 73,780,511 (+)	NCBI

RefSeq Acc Id:

XM_039109218 ⟹ XP_038965146

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	78,558,263 - 78,575,559 (+)	NCBI
mRatBN7.2	5	73,763,212 - 73,780,511 (+)	NCBI

RefSeq Acc Id:

XM_039109219 ⟹ XP_038965147

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	78,558,271 - 78,575,559 (+)	NCBI
mRatBN7.2	5	73,763,309 - 73,780,511 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_596913	(Get FASTA)	NCBI Sequence Viewer
	XP_038965141	(Get FASTA)	NCBI Sequence Viewer
	XP_038965142	(Get FASTA)	NCBI Sequence Viewer
	XP_038965144	(Get FASTA)	NCBI Sequence Viewer
	XP_038965145	(Get FASTA)	NCBI Sequence Viewer
	XP_038965146	(Get FASTA)	NCBI Sequence Viewer
	XP_038965147	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAG53887	(Get FASTA)	NCBI Sequence Viewer
	EDL91649	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000103543
	ENSRNOP00000103543.1

RefSeq Acc Id:

NP_596913 ⟸ NM_133422

- UniProtKB:

Q99PJ8 (UniProtKB/TrEMBL), A6KDV6 (UniProtKB/TrEMBL), F7EN42 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQALVPSDMMAGISPDPSALPLSEQSRAPRVDTLRGQESMLREDLESFRQKFRWFCYSQEEGPR
KTLNQLWELCKQWLRPDIHTKEQILELLVFEQFLRVLPGEMRIWVNSQHPESSVEVVTLVEDLN
QTLEEKEDRNTQAPDVCKEEDLGEEAMAAAPPSAEVAAPPRAEPREAVTFEDVSVDFTRGEWKL
LEPSQRELYKEVLLENLGSLEVLGSPVSKFDLISHLKWVKLPRVLEKELSKDPRPGESVKESES
RSELDAFMEELTLEKTVEYCFSGGGYGLKTEFQKRLGKPEKDHGRRKSHESKEAESGETTSEKN
VKQTSAMLKHRKALLTKTSQRSKEGKKPFSFHSALVNRRELSGGKSRKCSDREKDPHRPLSPTE
RKRHPKIGSLRKTEKCSKCGVDFTRILGCVESSQCEKCRKNLFQDETSSKDQEADTEEPRKCKK
CGKALEYGSKRSVCVECRNAHKASPSLKPQGKTDRRKKSYKCDECGKRFAEENDFSQHQRTHTR
EKPYVCKHCGRAFSDNSSFCQHQRIHTGEKPYTCKECGKSFTHSSSLSKHQRIHTGEKPYKCKE
CGKAFRQNSCLTRHQKIHTGEKPFLCKECGLSFRLFSSIMYHQRLHKGEKPYKCPHCEKGFPSH
SRLSRHLRIHTGAKPYKCKECGKTFRQSSSLNLHIRTHTGEKPYKCNYCGAAFTRSTILVEHVK
THTRVKYDCKKCGKSFKSRSANLRHHCTL

hide sequence

Ensembl Acc Id:

ENSRNOP00000020207 ⟸ ENSRNOT00000020207

RefSeq Acc Id:	XP_038965141 ⟸ XM_039109213
- Peptide Label:	isoform X1
- UniProtKB:	Q99PJ8 (UniProtKB/TrEMBL), A6KDV6 (UniProtKB/TrEMBL), F7EN42 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038965146 ⟸ XM_039109218
- Peptide Label:	isoform X1
- UniProtKB:	Q99PJ8 (UniProtKB/TrEMBL), A6KDV6 (UniProtKB/TrEMBL), F7EN42 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038965145 ⟸ XM_039109217
- Peptide Label:	isoform X1
- UniProtKB:	Q99PJ8 (UniProtKB/TrEMBL), A6KDV6 (UniProtKB/TrEMBL), F7EN42 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038965144 ⟸ XM_039109216
- Peptide Label:	isoform X1
- UniProtKB:	Q99PJ8 (UniProtKB/TrEMBL), A6KDV6 (UniProtKB/TrEMBL), F7EN42 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038965147 ⟸ XM_039109219
- Peptide Label:	isoform X1
- UniProtKB:	Q99PJ8 (UniProtKB/TrEMBL), A6KDV6 (UniProtKB/TrEMBL), F7EN42 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038965142 ⟸ XM_039109214
- Peptide Label:	isoform X1
- UniProtKB:	Q99PJ8 (UniProtKB/TrEMBL), A6KDV6 (UniProtKB/TrEMBL), F7EN42 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000103543 ⟸ ENSRNOT00000167599

Protein Domains

C2H2-type KRAB SCAN box

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q99PJ8-F1-model_v2	AlphaFold	Q99PJ8	1-733	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:727958	AgrOrtholog
BioCyc Gene	G2FUF-41165	BioCyc
Ensembl Genes	ENSRNOG00000014975	Ensembl
	ENSRNOG00000084203	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000167599	ENTREZGENE
	ENSRNOT00000167599.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.4020.10	UniProtKB/TrEMBL
	6.10.140.140	UniProtKB/TrEMBL
	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	KRAB_dom_sf	UniProtKB/TrEMBL
	Krueppel-associated_box	UniProtKB/TrEMBL
	SCAN_sf	UniProtKB/TrEMBL
	Tscrpt_reg_SCAN	UniProtKB/TrEMBL
	Znf_C2H2/integrase_DNA-bd	UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/TrEMBL
KEGG Report	rno:170955	UniProtKB/TrEMBL
NCBI Gene	170955	ENTREZGENE
PANTHER	B-CELL CLL_LYMPHOMA 6 MEMBER B PROTEIN	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN	UniProtKB/TrEMBL
Pfam	KRAB	UniProtKB/TrEMBL
	SCAN	UniProtKB/TrEMBL
	zf-C2H2	UniProtKB/TrEMBL
PhenoGen	Zfp483	PhenoGen
PROSITE	KRAB	UniProtKB/TrEMBL
	SCAN_BOX	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000014975	RatGTEx
	ENSRNOG00000084203	RatGTEx
SMART	KRAB	UniProtKB/TrEMBL
	SCAN	UniProtKB/TrEMBL
	ZnF_C2H2	UniProtKB/TrEMBL
Superfamily-SCOP	Krueppel-associated_box	UniProtKB/TrEMBL
	Retrovirus capsid dimerization domain-like	UniProtKB/TrEMBL
	SSF57667	UniProtKB/TrEMBL
UniProt	A6KDV6	ENTREZGENE, UniProtKB/TrEMBL
	F7EN42	ENTREZGENE, UniProtKB/TrEMBL
	Q99PJ8	ENTREZGENE
UniProt Secondary	Q99PJ8	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-07-19	Zfp483	zinc finger protein 483	Znf483	zinc finger protein 483	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-25	Znf483	zinc finger protein 483	Zkscan16	zinc finger with KRAB and SCAN domains 16	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-05-16	Zkscan16	zinc finger with KRAB and SCAN domains 16	Znf483	zinc finger protein 483	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-04	Znf483	zinc finger protein 483	Zfp483	zinc finger protein 483	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-11-17	Zfp483	zinc finger protein 483	Znf483		Symbol updated	1299863	APPROVED
2005-07-08	Znf483	zinc finger protein 483	Hit10	zinc finger protein HIT-10	Symbol and Name updated	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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