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Gene: Fbxo11 (F-box protein 11) Rattus norvegicus

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Symbol:

Fbxo11

Name:

F-box protein 11

RGD ID:

727935

Description:

Predicted to enable protein-arginine N-methyltransferase activity; ubiquitin-like ligase-substrate adaptor activity; and ubiquitin-protein transferase activity. Involved in negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel and positive regulation of protein catabolic process. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in breast carcinoma and lung non-small cell carcinoma. Orthologous to human FBXO11 (F-box protein 11); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

F-box only protein 11; F-box only protein 11-like; LOC103689957; Vit1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FBXO11 (F-box protein 11)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Fbxo11 (F-box protein 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Fbxo11 (F-box protein 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FBXO11 (F-box protein 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FBXO11 (F-box protein 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Fbxo11 (F-box protein 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FBXO11 (F-box protein 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FBXO11 (F-box protein 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Fbxo11 (F-box protein 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Fbxo11 (F-box protein 11)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	FBXO11 (F-box protein 11)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	FBXO11 (F-box protein 11)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Fbxo11 (F-box protein 11)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fbxo11a (F-box protein 11a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fbxo11b (F-box protein 11b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	BE0003N10.3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	FBXO11	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	dre-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	fbxo11	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	fbxo11	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	12,240,348 - 12,316,223 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	12,239,801 - 12,316,221 (+)	Ensembl				GRCr8
mRatBN7.2	6	6,486,761 - 6,562,664 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	6,486,015 - 6,562,662 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	6,820,525 - 6,844,805 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	7,129,930 - 7,154,210 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	6,657,075 - 6,681,355 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	11,662,356 - 11,737,427 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	11,662,356 - 11,686,682 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	21,398,929 - 21,414,145 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	6	21,634,305 - 21,709,376 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	11,542,561 - 11,566,829 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	6,301,914 - 6,326,193 (+)	NCBI		Celera
RGSC_v3.1	6	11,542,560 - 11,566,829 (-)	NCBI
Cytogenetic Map	6	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

breast carcinoma (ISO)

Developmental Disease (ISO)

genetic disease (ISO)

hepatitis B (ISO)

hepatocellular carcinoma (ISO)

hereditary breast ovarian cancer syndrome (ISO)

Hereditary Neoplastic Syndromes (ISO)

intellectual developmental disorder with dysmorphic facies and behavioral abnormalities (ISO)

intellectual disability (ISO)

lung non-small cell carcinoma (ISO)

Lynch syndrome (ISO)

Marfanoid Mental Retardation Syndrome, Autosomal (ISO)

Neurodevelopmental Disorders (ISO)

obesity (ISO)

otitis media (ISS)

stomach cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,6-dinitrotoluene (EXP)

acetylsalicylic acid (ISO)

aflatoxin B1 (ISO)

aflatoxin M1 (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bucladesine (ISO)

cadmium dichloride (EXP,ISO)

caffeine (ISO)

casticin (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dorsomorphin (ISO)

elemental selenium (ISO)

endosulfan (EXP)

ethanol (ISO)

folic acid (ISO)

formaldehyde (ISO)

graphene oxide (ISO)

GSK-J4 (ISO)

hydroquinone O-beta-D-glucopyranoside (ISO)

josamycin (ISO)

medroxyprogesterone acetate (ISO)

menadione (ISO)

methyl methanesulfonate (ISO)

oxaliplatin (EXP)

paracetamol (EXP)

paraquat (ISO)

picoxystrobin (ISO)

progesterone (ISO)

resveratrol (EXP,ISO)

rotenone (ISO)

SB 431542 (ISO)

selenium atom (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sulforaphane (ISO)

sunitinib (ISO)

tamoxifen (ISO)

topotecan (EXP)

trichloroethene (EXP)

tungsten (ISO)

valproic acid (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (IMP)

negative regulation of epithelial to mesenchymal transition (IEA,ISO,ISS)

positive regulation of protein catabolic process (IMP)

proteasome-mediated ubiquitin-dependent protein catabolic process (IEA,ISO,ISS)

protein ubiquitination (IEA)

regulation of apoptotic process (IBA)

sensory perception of sound (ISO)

ubiquitin-dependent protein catabolic process (IBA)

Cellular Component

chromosome (IEA)

cytoplasm (IEA,ISO)

nucleolus (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IEA,ISO)

SCF ubiquitin ligase complex (IEA,ISO)

Molecular Function

metal ion binding (IEA)

protein binding (ISO)

protein-arginine N-methyltransferase activity (IEA,ISO)

ubiquitin-like ligase-substrate adaptor activity (IEA,ISO,ISS)

ubiquitin-protein transferase activity (IEA,ISO)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

p53 signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	miR-324-5p upregulation potentiates resistance to cisplatin by targeting FBXO11 signalling in non-small cell lung cancer cells.	Ba Z, etal., J Biochem. 2019 Dec 1;166(6):517-527. doi: 10.1093/jb/mvz066.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Modulation of Ca2+-induced Ca2+ release by ubiquitin protein ligase E3 component n-recognin UBR3 and 6 in cardiac myocytes.	Ma XE, etal., Channels (Austin). 2020 Dec;14(1):326-335. doi: 10.1080/19336950.2020.1824957.
4.	The tumor suppressive miR-26a regulation of FBXO11 inhibits proliferation, migration and invasion of hepatocellular carcinoma cells.	Ma Y, etal., Biomed Pharmacother. 2018 May;101:648-655. doi: 10.1016/j.biopha.2018.02.118. Epub 2018 Mar 22.
5.	NCBI rat LocusLink and RefSeq merged data October 15, 2003	NCBI rat LocusLink and RefSeq merged data October 15, 2003
6.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	F-box protein 11 promotes the growth and metastasis of gastric cancer via PI3K/AKT pathway-mediated EMT.	Sun C, etal., Biomed Pharmacother. 2018 Feb;98:416-423. doi: 10.1016/j.biopha.2017.12.088. Epub 2017 Dec 27.
11.	LINC01436, regulating miR-585 and FBXO11, is an oncogenic lncRNA in the progression of gastric cancer.	Zhang Y, etal., Cell Biol Int. 2020 Mar;44(3):882-893. doi: 10.1002/cbin.11287. Epub 2020 Jan 8.
12.	PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis.	Zheng H, etal., Cancer Cell. 2014 Sep 8;26(3):358-373. doi: 10.1016/j.ccr.2014.07.022.

Additional References at PubMed

PMID:10932191	PMID:16487488	PMID:17035249	PMID:19028597	PMID:22113614

Genomics

Comparative Map Data

Fbxo11
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	12,240,348 - 12,316,223 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	12,239,801 - 12,316,221 (+)	Ensembl				GRCr8
mRatBN7.2	6	6,486,761 - 6,562,664 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	6,486,015 - 6,562,662 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	6,820,525 - 6,844,805 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	7,129,930 - 7,154,210 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	6,657,075 - 6,681,355 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	11,662,356 - 11,737,427 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	11,662,356 - 11,686,682 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	21,398,929 - 21,414,145 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	6	21,634,305 - 21,709,376 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	11,542,561 - 11,566,829 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	6,301,914 - 6,326,193 (+)	NCBI		Celera
RGSC_v3.1	6	11,542,560 - 11,566,829 (-)	NCBI
Cytogenetic Map	6	q12	NCBI

FBXO11
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	47,806,920 - 47,906,498 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	47,789,316 - 47,906,507 (-)	Ensembl			hg38	GRCh38
GRCh37	2	48,034,059 - 48,133,637 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	47,887,563 - 47,986,318 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	47,957,375 - 48,044,465	NCBI
Celera	2	47,873,581 - 47,972,357 (-)	NCBI		Celera
Cytogenetic Map	2	p16.3	NCBI
HuRef	2	47,770,542 - 47,869,544 (-)	NCBI		HuRef
CHM1_1	2	47,964,454 - 48,063,258 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	47,812,869 - 47,912,466 (-)	NCBI		T2T-CHM13v2.0

Fbxo11
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	88,298,287 - 88,373,473 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	88,298,287 - 88,372,719 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	87,990,859 - 88,066,045 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	87,990,859 - 88,065,291 (-)	Ensembl			mm10	GRCm38
MGSCv37	17	88,390,199 - 88,464,625 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	87,899,185 - 87,973,611 (-)	NCBI		MGSCv36	mm8
Celera	17	92,401,160 - 92,425,975 (-)	NCBI		Celera
Cytogenetic Map	17	E4	NCBI
cM Map	17	57.87	NCBI

Fbxo11
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955441	14,471,283 - 14,553,916 (-)	Ensembl
ChiLan1.0	NW_004955441	14,471,283 - 14,495,508 (-)	NCBI	ChiLan1.0	ChiLan1.0

FBXO11
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	78,478,591 - 78,577,716 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	78,482,579 - 78,582,236 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	47,926,629 - 48,026,245 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	48,849,746 - 48,948,007 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	48,830,780 - 48,886,300 (-)	Ensembl			panPan2	panpan1.1

FBXO11
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	49,838,003 - 49,864,211 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	49,838,776 - 49,925,064 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	49,693,555 - 49,780,653 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	50,711,840 - 50,799,252 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	50,711,894 - 50,799,655 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	50,419,057 - 50,506,412 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	50,705,887 - 50,793,282 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	50,893,652 - 50,980,961 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Fbxo11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	33,194,074 - 33,280,085 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936508	4,685,595 - 4,708,694 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936508	4,622,695 - 4,708,694 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FBXO11
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	92,696,441 - 92,792,616 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	92,696,402 - 92,792,623 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	98,680,348 - 98,710,235 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FBXO11
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	59,276,380 - 59,375,635 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	59,276,447 - 59,374,442 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666045	52,468,631 - 52,568,736 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fbxo11
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624738	29,108,809 - 29,191,368 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624738	29,108,759 - 29,190,725 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Fbxo11
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	7	4,936,057 - 5,011,008 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Fbxo11
772 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	104
Count of miRNA genes:	96
Interacting mature miRNAs:	99
Transcripts:	ENSRNOT00000021998
Prediction methods:	Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8552962	Pigfal16	Plasma insulin-like growth factor 1 level QTL 16	9.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	1975879	46975879	Rat
7411603	Foco13	Food consumption QTL 13	5.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1975879	46975879	Rat
1598843	Cm63	Cardiac mass QTL 63	2.6		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	1	44788383	Rat
7411542	Bw127	Body weight QTL 127	5.5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	1975879	46975879	Rat
2293706	Bmd20	Bone mineral density QTL 20	4.3	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	6	1	25740059	Rat
2292616	Ept15	Estrogen-induced pituitary tumorigenesis QTL 15	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	1	44788383	Rat
9589048	Scfw3	Subcutaneous fat weight QTL 3	4.57	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	6	1975879	46975879	Rat
2301964	Bp323	Blood pressure QTL 323	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	86868070	Rat
2293709	Bss23	Bone structure and strength QTL 23	5.18	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	6	3239989	48239989	Rat
2293650	Bss31	Bone structure and strength QTL 31	5.05	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	6	3239989	48239989	Rat
1300128	Rf16	Renal function QTL 16	3.89		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	1	40163351	Rat
70196	BpQTLcluster7	Blood pressure QTL cluster 7	6.82		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	20510098	Rat
1300164	Rf15	Renal function QTL 15	3.12		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	3239989	48239989	Rat
1358190	Ept1	Estrogen-induced pituitary tumorigenesis QTL 1	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	1	44788383	Rat
2293656	Bss28	Bone structure and strength QTL 28	6.79	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	6	3239989	48239989	Rat
9589129	Insul24	Insulin level QTL 24	19.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	6	1975879	46975879	Rat

Markers in Region

RH126790

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	6,562,426 - 6,562,642 (-)	MAPPER	mRatBN7.2
Rnor_6.0	6	11,662,378 - 11,662,593	NCBI	Rnor6.0
Rnor_5.0	6	21,634,327 - 21,634,542	UniSTS	Rnor5.0
RGSC_v3.4	6	11,542,581 - 11,542,796	UniSTS	RGSC3.4
Celera	6	6,325,958 - 6,326,173	UniSTS
Cytogenetic Map	6	q12	UniSTS

RH140511

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	6,562,226 - 6,562,406 (-)	MAPPER	mRatBN7.2
Rnor_6.0	6	11,662,614 - 11,662,793	NCBI	Rnor6.0
Rnor_5.0	6	21,634,563 - 21,634,742	UniSTS	Rnor5.0
RGSC_v3.4	6	11,542,817 - 11,542,996	UniSTS	RGSC3.4
Celera	6	6,325,758 - 6,325,937	UniSTS
Cytogenetic Map	6	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_181631	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764477	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594113	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112126	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112127	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261802	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY274810	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228097	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021998 ⟹ ENSRNOP00000021998

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	12,239,801 - 12,316,221 (+)	Ensembl
mRatBN7.2 Ensembl	6	6,486,015 - 6,562,662 (+)	Ensembl
Rnor_6.0 Ensembl	6	11,662,356 - 11,686,682 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093590

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	6	11,663,240 - 11,663,788 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000165520 ⟹ ENSRNOP00000110764

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	12,279,152 - 12,316,221 (+)	Ensembl

RefSeq Acc Id:

NM_181631 ⟹ NP_853662

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	12,291,942 - 12,316,221 (+)	NCBI
mRatBN7.2	6	6,538,383 - 6,562,662 (+)	NCBI
Rnor_6.0	6	11,662,358 - 11,686,682 (-)	NCBI
Rnor_5.0	6	21,634,305 - 21,709,376 (-)	NCBI
RGSC_v3.4	6	11,542,561 - 11,566,829 (-)	RGD
Celera	6	6,301,914 - 6,326,193 (+)	RGD

Sequence:

show sequence

GATGATGTTCCTGCAGATATGGTTGCAGAAGAATCAGGTCCTGGTGCACAAAACAGTCCATACC
AGCTTCGTAGAAAAACTCTTTTGCCAAAAAGAACAGCGTGTCCTACAAAGAACAGCATGGAGGG
CGCCTCTACTTCAACTACAGAAAACTTCGGCCATCGAGCGAAGCGGGCAAGAGTGTCTGGGAAG
TCACAAGATCTGTCAGCAGCACCCGCTGAACAGTATCTTCAGGAGAAGCTACCAGATGAAGTAG
TTTTAAAAATATTCTCTTATTTGCTGGAACAAGATCTTTGTAGAGCTGCTTGTGTGTGTAAACG
CTTCAGTGAACTTGCTAATGATCCAATTTTGTGGAAACGATTATATATGGAAGTATTTGAATAT
ACCCGGCCTATGATGCATCCTGAACCTGGTAAATTCTACCAGATTAATCCAGAAGAATATGAAC
ATCCAAATCCATGGAAAGAGAGTTTTCAACAGTTGTATAAAGGTGCACACGTAAAGCCGGGATT
TGCGGAACATTTCTATAGTAATCCTGCCAGATACAAAGGGAGAGAAAACATGTTGTATTATGAT
ACTATTGAAGATGCCCTTGGCGGAGTACAAGAAGCACATTTTGATGGGCTTATCTTTGTTCATT
CTGGAATATATACTGATGAATGGATATATATTGAATCTCCAATCACTATGATTGGTGCAGCACC
TGGGAAGGTTGCAGACAAGGTCATCATTGAGAACACTAGAGACTCCACTTTCGTTTTTATGGAA
GGTTCTGAGGACGCTTACGTTGGATATATGACAATAAGATTCAACCCTGATGACAAATCTGCCC
AGCATCACAACGCGCACCACTGCCTAGAGATCACAGTCAACTGCAGCCCCATTATCGACCACTG
TATCATCCGAAGCACATGCACAGTTGGCTCTGCAGTGTGTGTCAGCGGTCAGGGGGCGTGTCCC
ACTATCAAGCATTGTAACATCAGTGACTGTGAAAACGTCGGCCTCTATATAACAGATCATGCAC
AGGGAATATATGAAGATAATGAAATTTCTAATAATGCATTAGCTGGGATTTGGGTTAAAAATCA
TGGAAATCCAATTATTAGACGGAATCACATTCATCATGGACGTGATGTTGGTGTATTCACATTT
GATCATGGCATGGGCTACTTTGAAAGTTGCAACATACACAGAAACAGGATAGCAGGCTTTGAGG
TAAAAGCCTACGCTAATCCCACAGTGGTTCGATGTGAAATTCACCATGGGCAGACTGGAGGAAT
ATATGTCCATGAGAAAGGAAGAGGACAATTTATAGAGAATAAAATCTATGCAAACAACTTCGCA
GGCGTATGGATTACCTCAAATAGTGACCCAACAATAAGGGGGAATTCTATATTTAATGGAAATC
AAGGAGGAGTTTACATCTTTGGTGATGGACGAGGCCTTATAGAAGGAAATGACATTTATGGTAA
TGCGTTAGCAGGAATTCAGATTAGGACAAACAGTTGTCCTATTGTTCGACATAACAAAATTCAC
GATGGACAGCATGGTGGGATTTATGTGCATGAAAAGGGACAAGGTGTAATAGAAGAAAATGAAG
TTTACAGCAACACCCTGGCTGGCGTCTGGGTGACAACTGGCAGCACGCCAGTACTAAGAAGAAA
TCGGATACACAGTGGCAAGCAGGTCGGTGTTTATTTCTATGACAATGGACATGGTGTTCTAGAA
GATAACGATATCTACAATCATATGTATTCAGGGGTTCAGATAAGGACTGGAAGCAACCCCAAAA
TTAGAAGAAACAAAATTTGGGGAGGACAAAATGGTGGAATTCTAGTTTATAATTCTGGTCTAGG
CTGTATAGAAGACAATGAAATCTTCGACAACGCAATGGCTGGCGTCTGGATTAAAACAGACAGC
AATCCTACGCTGAGACGGAATAAAATCCACGATGGAAGGGATGGCGGCATCTGTATATTTAATG
GGGGTCGAGGTCTCCTTGAAGAAAATGATATTTTCAGGAACGCTCAAGCAGGTGTTCTTATCAG
CACCAACAGTCATCCAGTCTTAAGAAAAAACAGAATATTCGATGGATTTGCTGCAGGTATTGAA
ATTACAAATCATGCAACTGCAACACTAGAAGGCAATCAGATTTTTAACAACAGATTTGGAGGCT
TATTTTTAGCATCTGGTGTTAACGTGACAATGAAAGATAACAAGATAATGAACAATCAAGATGC
CATAGAAAAGGCTGTTAGTAGAGGACAATGTTTATATAAAATATCAAGTTATACCAGCTATCCC
ATGCATGACTTCTACAGATGTCATACTTGTAACACCACAGATCGAAATGCCATATGTGTGAACT
GCATTAAGAAGTGCCATCAGGGACATGATGTAGAGTTCATTAGACATGATAGGTTTTTCTGTGA
CTGTGGTGCTGGAACACTGTCCAATCCTTGTACATTAGCTGGTGAGCCAACACATGATACAGAC
ACACTATATGACTCTGCCCCACCTATAGAGTCTAATACGTTGCAGCACAACTGAACTCCTTCCC
TAAGAAAAAGTCCTGCCATCCTAACATAACTTAAAACATCTTTTGGAAGATAAAATACTTGCCC
ATGCTACAGAAAGAGACTGTACTGAAAAAATGGACACACAAGGTCAGTTGACACTATGAAGCTC
AAGCTACCAAAAAGAAAGTGGCAATATATTGACTCAGGATCTCAAGGCTGGGTATTTTAGCATT
ACTGTGTAAAGACTTTGAAGGGACAGAAGTGAAGAAATAAGCTGCAGTTTTGTACAGATGCCAA
CCTCTGGAAAGCTGGTGTTGTTACAGCTAGCATCGAATGCAGTCTGACTTGCAGTAGTGACCTT
CAACAGACTTCAGCTTTGTCGCTGCCGTTATGGACATGGGTACCAATTGCTTTTGTAATATGGT
AAATGTGAGCTAGCACTTCTGCATTGATTTTTTTTAACATGTATTCAGATTGAGAATATGATTT
TAATGCTTTAATCTCATGTAGTTTGTTTTTAATTTCAAGCCAATCTTATTGTACTTGAATGTGC
CCTGTTTTGTTAGCACACCTAGACTTGCTGTAACTGTACTCATGTCCCAGATGTACGTTCTTTC
TATGAAAGAGAAAAACACTAATCTTAAATTATATCCAGCAATGTTTCTGGTATCCTTTAAGAAA
AGTTAAGACTATTATTTCCTTCCCTTTCCTGTGCAGCATTCAAAAAAAAAAAAAATCACCCCTA
GAAAAAGTGAGTGTTTTAATGAGACTTCCTAGGAAGGGATGCACTGTAAAACAAAAGTATTCTT
GTATCTCAGTTTTGTGAAAGGTAAAAACTACTATGTTTTAAAGTACACTTTAGAAAGTCTCTTC
AAAACAGTCCTGTATTTGAACTCTGTTCATAGTTTTTATTTGAACAGTTTAGACAAAACAGCTG
GAAATTACGGCAATTTCCTGCATTAAGCTGAGACCAGTATATATGCAGCTCTATACAGTTTCAT
AGCGCCCCCCCCCATTTATGTGTATTGGTGACAGTGGGTATAAACAGCCTGAAAGTGTATGCAT
GTACCATAACATCTAGACTTAATATATTGTGGAGTATTCAATAACCATTATGTAGAAGGTAGAT
AAGAATTAAAAGGGTTTAATTTCCTAGAAAGAAAATGGAAAAATGGTCATTTTTAAAAAATAAA
GTTTATTAGATCAT

hide sequence

RefSeq Acc Id:

XM_017594113 ⟹ XP_017449602

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	12,240,683 - 12,316,223 (+)	NCBI
mRatBN7.2	6	6,487,135 - 6,562,664 (+)	NCBI
Rnor_6.0	6	11,662,356 - 11,737,427 (-)	NCBI

Sequence:

show sequence

TGCCGCGCTTTGTTTGGTTTCGGGGCCGGCACCCTCCGTCCCCACCCCTCCTCGGGGCTTCCCG
GCTGGCTCACCCACCCCACGGGAGTCTGTTCGCGGCCGGAGGCGGGTAGAGGGTGGGATTTCCC
CCCTTTCTGCCGCCTGGCTCGGTCTGGGCTCCCCCTTTCTCGTGATGATGTTCCTGCAGATATG
GTTGCAGAAGAATCAGGTCCTGGTGCACAAAACAGTCCATACCAGCTTCGTAGAAAAACTCTTT
TGCCAAAAAGAACAGCGTGTCCTACAAAGAACAGCATGGAGGGCGCCTCTACTTCAACTACAGA
AAACTTCGGCCATCGAGCGAAGCGGGCAAGAGTGTCTGGGAAGTCACAAGATCTGTCAGCAGCA
CCCGCTGAACAGTATCTTCAGGAGAAGCTACCAGATGAAGTAGTTTTAAAAATATTCTCTTATT
TGCTGGAACAAGATCTTTGTAGAGCTGCTTGTGTGTGTAAACGCTTCAGTGAACTTGCTAATGA
TCCAATTTTGTGGAAACGATTATATATGGAAGTATTTGAATATACCCGGCCTATGATGCATCCT
GAACCTGGTAAATTCTACCAGATTAATCCAGAAGAATATGAACATCCAAATCCATGGAAAGAGA
GTTTTCAACAGTTGTATAAAGGTGCACACGTAAAGCCGGGATTTGCGGAACATTTCTATAGTAA
TCCTGCCAGATACAAAGGGAGAGAAAACATGTTGTATTATGATACTATTGAAGATGCCCTTGGC
GGAGTACAAGAAGCACATTTTGATGGGCTTATCTTTGTTCATTCTGGAATATATACTGATGAAT
GGATATATATTGAATCTCCAATCACTATGATTGGTGCAGCACCTGGGAAGGTTGCAGACAAGGT
CATCATTGAGAACACTAGAGACTCCACTTTCGTTTTTATGGAAGGTTCTGAGGACGCTTACGTT
GGATATATGACAATAAGATTCAACCCTGATGACAAATCTGCCCAGCATCACAACGCGCACCACT
GCCTAGAGATCACAGTCAACTGCAGCCCCATTATCGACCACTGTATCATCCGAAGCACATGCAC
AGTTGGCTCTGCAGTGTGTGTCAGCGGTCAGGGGGCGTGTCCCACTATCAAGCATTGTAACATC
AGTGACTGTGAAAACGTCGGCCTCTATATAACAGATCATGCACAGGGAATATATGAAGATAATG
AAATTTCTAATAATGCATTAGCTGGGATTTGGGTTAAAAATCATGGAAATCCAATTATTAGACG
GAATCACATTCATCATGGACGTGATGTTGGTGTATTCACATTTGATCATGGCATGGGCTACTTT
GAAAGTTGCAACATACACAGAAACAGGATAGCAGGCTTTGAGGTAAAAGCCTACGCTAATCCCA
CAGTGGTTCGATGTGAAATTCACCATGGGCAGACTGGAGGAATATATGTCCATGAGAAAGGAAG
AGGACAATTTATAGAGAATAAAATCTATGCAAACAACTTCGCAGGCGTATGGATTACCTCAAAT
AGTGACCCAACAATAAGGGGGAATTCTATATTTAATGGAAATCAAGGAGGAGTTTACATCTTTG
GTGATGGACGAGGCCTTATAGAAGGAAATGACATTTATGGTAATGCGTTAGCAGGAATTCAGAT
TAGGACAAACAGTTGTCCTATTGTTCGACATAACAAAATTCACGATGGACAGCATGGTGGGATT
TATGTGCATGAAAAGGGACAAGGTGTAATAGAAGAAAATGAAGTTTACAGCAACACCCTGGCTG
GCGTCTGGGTGACAACTGGCAGCACGCCAGTACTAAGAAGAAATCGGATACACAGTGGCAAGCA
GGTCGGTGTTTATTTCTATGACAATGGACATGGTGTTCTAGAAGATAACGATATCTACAATCAT
ATGTATTCAGGGGTTCAGATAAGGACTGGAAGCAACCCCAAAATTAGAAGAAACAAAATTTGGG
GAGGACAAAATGGTGGAATTCTAGTTTATAATTCTGGTCTAGGCTGTATAGAAGACAATGAAAT
CTTCGACAACGCAATGGCTGGCGTCTGGATTAAAACAGACAGCAATCCTACGCTGAGACGGAAT
AAAATCCACGATGGAAGGGATGGCGGCATCTGTATATTTAATGGGGGTCGAGGTCTCCTTGAAG
AAAATGATATTTTCAGGAACGCTCAAGCAGGTGTTCTTATCAGCACCAACAGTCATCCAGTCTT
AAGAAAAAACAGAATATTCGATGGATTTGCTGCAGGTATTGAAATTACAAATCATGCAACTGCA
ACACTAGAAGGCAATCAGATTTTTAACAACAGATTTGGAGGCTTATTTTTAGCATCTGGTGTTA
ACGTGACAATGAAAGATAACAAGATAATGAACAATCAAGATGCCATAGAAAAGGCTGTTAGTAG
AGGACAATGTTTATATAAAATATCAAGTTATACCAGCTATCCCATGCATGACTTCTACAGATGT
CATACTTGTAACACCACAGATCGAAATGCCATATGTGTGAACTGCATTAAGAAGTGCCATCAGG
GACATGATGTAGAGTTCATTAGACATGATAGGTTTTTCTGTGACTGTGGTGCTGGAACACTGTC
CAATCCTTGTACATTAGCTGGTGAGCCAACACATGATACAGACACACTATATGACTCTGCCCCA
CCTATAGAGTCTAATACGTTGCAGCACAACTGAACTCCTTCCCTAAGAAAAAGTCCTGCCATCC
TAACATAACTTAAAACATCTTTTGGAAGATAAAATACTTGCCCATGCTACAGAAAGAGACTGTA
CTGAAAAAATGGACACACAAGGTCAGTTGACACTATGAAGCTCAAGCTACCAAAAAGAAAGTGG
CAATATATTGACTCAGGATCTCAAGGCTGGGTATTTTAGCATTACTGTGTAAAGACTTTGAAGG
GACAGAAGTGAAGAAATAAGCTGCAGTTTTGTACAGATGCCAACCTCTGGAAAGCTGGTGTTGT
TACAGCTAGCATCGAATGCAGTCTGACTTGCAGTAGTGACCTTCAACAGACTTCAGCTTTGTCG
CTGCCGTTATGGACATGGGTACCAATTGCTTTTGTAATATGGTAAATGTGAGCTAGCACTTCTG
CATTGATTTTTTTTAACATGTATTCAGATTGAGAATATGATTTTAATGCTTTAATCTCATGTAG
TTTGTTTTTAATTTCAAGCCAATCTTATTGTACTTGAATGTGCCCTGTTTTGTTAGCACACCTA
GACTTGCTGTAACTGTACTCATGTCCCAGATGTACGTTCTTTCTATGAAAGAGAAAAACACTAA
TCTTAAATTATATCCAGCAATGTTTCTGGTATCCTTTAAGAAAAGTTAAGACTATTATTTCCTT
CCCTTTCCTGTGCAGCATTCAAAAAAAAAAAAATCACCCCTAGAAAAAGTGAGTGTTTTAATGA
GACTTCCTAGGAAGGGATGCACTGTAAAACAAAAGTATTCTTGTATCTCAGTTTTGTGAAAGGT
AAAAACTACTATGTTTTAAAGTACACTTTAGAAAGTCTCTTCAAAACAGTCCTGTATTTGAACT
CTGTTCATAGTTTTTATTTGAACAGTTTAGACAAAACAGCTGGAAATTACGGCAATTTCCTGCA
TTAAGCTGAGACCAGTATATATGCAGCTCTATACAGTTTCATAGCGCCCCCCCCCATTTATGTG
TATTGGTGACAGTGGGTATAAACAGCCTGAAAGTGTATGCATGTACCATAACATCTAGACTTAA
TATATTGTGGAGTATTCAATAACCATTATGTAGAAGGTAGATAAGAATTAAAAGGGTTTAATTT
CCTAGAAAGAAAATGGAAAAATGGTCATTTTTAAAAAATAAAGTTTATTAGATCATAA

hide sequence

RefSeq Acc Id:

XM_039112126 ⟹ XP_038968054

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	12,240,348 - 12,316,223 (+)	NCBI
mRatBN7.2	6	6,486,761 - 6,562,664 (+)	NCBI

RefSeq Acc Id:

XM_039112127 ⟹ XP_038968055

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	12,240,348 - 12,316,223 (+)	NCBI
mRatBN7.2	6	6,486,761 - 6,562,664 (+)	NCBI

RefSeq Acc Id:

XM_063261802 ⟹ XP_063117872

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	12,240,905 - 12,316,223 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_853662	(Get FASTA)	NCBI Sequence Viewer
	XP_017449602	(Get FASTA)	NCBI Sequence Viewer
	XP_038968054	(Get FASTA)	NCBI Sequence Viewer
	XP_038968055	(Get FASTA)	NCBI Sequence Viewer
	XP_063117872	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAP42075	(Get FASTA)	NCBI Sequence Viewer
	EDM02630	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000021998
	ENSRNOP00000110764
GenBank Protein	Q7TSL3	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_853662 ⟸ NM_181631

- UniProtKB:

Q7TSL3 (UniProtKB/Swiss-Prot), A6H9C5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQDLSA
APAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMH
PEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRENMLYYDTIEDAL
GGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIENTRDSTFVFMEGSEDAY
VGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVSGQGACPTIKHCN
ISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGVFTFDHGMGY
FESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITS
NSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGG
IYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYN
HMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRR
NKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPVLRKNRIFDGFAAGIEITNHAT
ATLEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYR
CHTCNTTDRNAICVNCIKKCHQGHDVEFIRHDRFFCDCGAGTLSNPCTLAGEPTHDTDTLYDSA
PPIESNTLQHN

hide sequence

RefSeq Acc Id:	XP_017449602 ⟸ XM_017594113
- Peptide Label:	isoform X4
- UniProtKB:	Q7TSL3 (UniProtKB/Swiss-Prot), A6H9C5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQDLSA APAEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMH PEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRENMLYYDTIEDAL GGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIENTRDSTFVFMEGSEDAY VGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVSGQGACPTIKHCN ISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGVFTFDHGMGY FESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITS NSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGG IYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYN HMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRR NKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPVLRKNRIFDGFAAGIEITNHAT ATLEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYR CHTCNTTDRNAICVNCIKKCHQGHDVEFIRHDRFFCDCGAGTLSNPCTLAGEPTHDTDTLYDSA PPIESNTLQHN hide sequence

Ensembl Acc Id:

ENSRNOP00000021998 ⟸ ENSRNOT00000021998

RefSeq Acc Id:	XP_038968054 ⟸ XM_039112126
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2QBJ7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968055 ⟸ XM_039112127
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063117872 ⟸ XM_063261802
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000110764 ⟸ ENSRNOT00000165520

Protein Domains

F-box UBR-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q7TSL3-F1-model_v2	AlphaFold	Q7TSL3	1-843	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:727935	AgrOrtholog
BioCyc Gene	G2FUF-38751	BioCyc
Ensembl Genes	ENSRNOG00000016396	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000021998	ENTREZGENE
	ENSRNOT00000165520	ENTREZGENE
Gene3D-CATH	1.20.1280.50	UniProtKB/Swiss-Prot
	2.160.20.10	UniProtKB/Swiss-Prot
InterPro	Beta_helix	UniProtKB/Swiss-Prot
	Carb-bd_sugar_hydrolysis-dom	UniProtKB/Swiss-Prot
	F-box-like_dom_sf	UniProtKB/Swiss-Prot
	F-box_dom	UniProtKB/Swiss-Prot
	F-box_FBXO11	UniProtKB/Swiss-Prot
	FBXO11_UBR-box	UniProtKB/Swiss-Prot
	NosD_dom	UniProtKB/Swiss-Prot
	Para_beta_helix_rpt-2	UniProtKB/Swiss-Prot
	PbH1	UniProtKB/Swiss-Prot
	Pectin_lyas_fold	UniProtKB/Swiss-Prot
	Pectin_lyase_fold/virulence	UniProtKB/Swiss-Prot
	SCF-Subunits/Alg-Epimerases	UniProtKB/Swiss-Prot
	Znf_UBR	UniProtKB/Swiss-Prot
KEGG Report	rno:301674	UniProtKB/Swiss-Prot
NCBI Gene	301674	ENTREZGENE
PANTHER	F-BOX ONLY PROTEIN	UniProtKB/Swiss-Prot
	PTHR22990:SF20	UniProtKB/Swiss-Prot
Pfam	Beta_helix	UniProtKB/Swiss-Prot
	F-box-like	UniProtKB/Swiss-Prot
	NosD	UniProtKB/Swiss-Prot
	zf-UBR	UniProtKB/Swiss-Prot
PhenoGen	Fbxo11	PhenoGen
PROSITE	FBOX	UniProtKB/Swiss-Prot
	ZF_UBR	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000016396	RatGTEx
SMART	CASH	UniProtKB/Swiss-Prot
	FBOX	UniProtKB/Swiss-Prot
	PbH1	UniProtKB/Swiss-Prot
	ZnF_UBR1	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF51126	UniProtKB/Swiss-Prot
	SSF81383	UniProtKB/Swiss-Prot
UniProt	A0A8L2QBJ7	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0M5P0_RAT	UniProtKB/TrEMBL
	A6H9C5	ENTREZGENE, UniProtKB/TrEMBL
	FBX11_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Fbxo11	F-box protein 11	LOC103689957	F-box only protein 11-like	Data merged from RGD:9197316	737654	PROVISIONAL
2014-08-25	LOC103689957	F-box only protein 11-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-03-04	Fbxo11	F-box protein 11	Fbxo11	F-box only protein 11	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-09-30	Fbxo11				Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)