Rnasel (ribonuclease L) - Rat Genome Database

Name: Rnasel
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Rnasel (ribonuclease L) Rattus norvegicus

Analyze

Symbol:

Rnasel

Name:

ribonuclease L

RGD ID:

727933

Description:

Enables RNA nuclease activity and rRNA binding activity. Involved in rRNA processing. Located in nuclear matrix. Human ortholog(s) of this gene implicated in Lynch syndrome and prostate cancer. Orthologous to human RNASEL (ribonuclease L); PARTICIPATES IN hepatitis C pathway; influenza A pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; acetamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

2-5A-dependent ribonuclease; ribonuclease L (2 5-oligoisoadenylate synthetase-dependent); ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent); ribonuclease L (2, 5-oligoisoadenylate synthetase-dependent)

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RNASEL (ribonuclease L)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Rnasel (ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rnasel (ribonuclease L)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RNASEL (ribonuclease L)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RNASEL (ribonuclease L)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rnasel (ribonuclease L)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RNASEL (ribonuclease L)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RNASEL (ribonuclease L)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rnasel (ribonuclease L)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	RNASEL (ribonuclease L)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rnasel (ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	68,446,641 - 68,460,804 (+)	NCBI		GRCr8
mRatBN7.2	13	65,894,990 - 65,910,354 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	65,901,459 - 65,908,704 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	68,502,520 - 68,509,768 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	69,792,702 - 69,799,948 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	67,049,541 - 67,056,829 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	71,188,712 - 71,202,636 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	71,192,142 - 71,202,625 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	76,153,998 - 76,167,666 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	68,822,013 - 68,829,264 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	68,836,092 - 68,843,336 (+)	NCBI
Celera	13	65,801,918 - 65,809,169 (+)	NCBI		Celera
Cytogenetic Map	13	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

1q24 Deletion Syndrome (ISO)

Animal Viral Hepatitis (ISO)

anthrax disease (ISO)

autosomal recessive chronic granulomatous disease 2 (ISO)

breast cancer (ISO)

Cardiovirus Infections (ISO)

chronic obstructive pulmonary disease (ISO)

colon adenocarcinoma (ISO)

Escherichia Coli Infections (ISO)

Experimental Colitis (ISO)

Experimental Liver Cirrhosis (ISO)

Familial Prostate Cancer (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

genital herpes (ISO)

hepatitis B (ISO)

Hereditary Neoplastic Syndromes (ISO)

herpes simplex virus keratitis (ISO)

influenza (ISO)

Lynch syndrome (ISO)

Murine Acquired Immunodeficiency Syndrome (ISO)

ovarian cancer (ISO)

parathyroid carcinoma (ISO)

prostate cancer (ISO)

Prostate Cancer, Hereditary, 1 (ISO)

Prostatic Neoplasms (ISO)

vaccinia (ISO)

West Nile encephalitis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-diaminodiphenylmethane (EXP)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

cisplatin (ISO)

cobalt dichloride (EXP)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

D-glucose (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP,ISO)

diclofenac (ISO)

dieldrin (EXP)

folic acid (ISO)

gentamycin (EXP)

glucose (ISO)

hexadecanoic acid (ISO)

hydroquinone (ISO)

inulin (ISO)

lead diacetate (EXP)

metformin (ISO)

methoxyacetic acid (EXP)

N-nitrosodimethylamine (EXP)

nickel atom (ISO)

ozone (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

S-adenosyl-L-methioninate (ISO)

S-adenosyl-L-methionine (ISO)

silicon dioxide (ISO)

sodium fluoride (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (EXP)

tungsten (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

defense response to virus (IBA)

fat cell differentiation (ISO)

mRNA processing (IEA)

negative regulation of viral genome replication (IBA,ISO)

positive regulation of glucose import (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of mRNA stability (ISO)

RNA processing (IBA)

rRNA processing (IDA)

Cellular Component

nuclear matrix (IDA)

Molecular Function

ATP binding (IEA)

identical protein binding (ISO)

protein binding (ISO)

protein kinase activity (IEA)

ribonucleoprotein complex binding (ISO)

RNA binding (IBA,ISO)

RNA nuclease activity (IBA,IDA,ISO)

rRNA binding (IDA)

Molecular Pathway Annotations Click to see Annotation Detail View

hepatitis C pathway (IEA)

influenza A pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Dichotomy between survival and lytic gene expression in RNase L- and PKR-deficient mice transduced with an adenoviral vector expressing murine IFN-beta following ocular HSV-1 infection.	Al-Khatib K, etal., Exp Eye Res. 2005 Feb;80(2):167-73. doi: 10.1016/j.exer.2004.08.026.
2.	RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases.	Casey G, etal., Nat Genet. 2002 Dec;32(4):581-3. Epub 2002 Nov 4.
3.	Mutations in ribonuclease L gene do not occur at a greater frequency in patients with familial prostate cancer compared with patients with sporadic prostate cancer.	Downing SR, etal., Clin Prostate Cancer. 2003 Dec;2(3):177-80.
4.	Herpes simplex virus type 2-mediated disease is reduced in mice lacking RNase L.	Duerst RJ and Morrison LA, Virology. 2007 Apr 10;360(2):322-8. doi: 10.1016/j.virol.2006.10.042. Epub 2006 Dec 6.
5.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
7.	Lineage A Betacoronavirus NS2 Proteins and the Homologous Torovirus Berne pp1a Carboxy-Terminal Domain Are Phosphodiesterases That Antagonize Activation of RNase L.	Goldstein SA, etal., J Virol. 2017 Feb 14;91(5). pii: JVI.02201-16. doi: 10.1128/JVI.02201-16. Print 2017 Mar 1.
8.	Interferon-regulated pathways that control hepatitis B virus replication in transgenic mice.	Guidotti LG, etal., J Virol. 2002 Mar;76(6):2617-21. doi: 10.1128/jvi.76.6.2617-2621.2002.
9.	Inhibition of RNase L and RNA-dependent protein kinase (PKR) by sunitinib impairs antiviral innate immunity.	Jha BK, etal., J Biol Chem. 2011 Jul 29;286(30):26319-26. doi: 10.1074/jbc.M111.253443. Epub 2011 Jun 2.
10.	Arg462Gln sequence variation in the prostate-cancer-susceptibility gene RNASEL and age of onset of hereditary non-polyposis colorectal cancer: a case-control study.	Kruger S, etal., Lancet Oncol. 2005 Aug;6(8):566-72.
11.	Ribonuclease L is not critical for innate restriction and adaptive immunity against Friend retrovirus infection.	Li SX, etal., Virology. 2013 Aug 15;443(1):134-42. doi: 10.1016/j.virol.2013.05.009. Epub 2013 May 29.
12.	An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.	Li XL, etal., Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20816-21. doi: 10.1073/pnas.0807265105. Epub 2008 Dec 15.
13.	RNase-L deficiency exacerbates experimental colitis and colitis-associated cancer.	Long TM, etal., Inflamm Bowel Dis. 2013 May;19(6):1295-305. doi: 10.1097/MIB.0b013e318281f2fd.
14.	NCBI rat LocusLink and RefSeq merged data October 15, 2003	NCBI rat LocusLink and RefSeq merged data October 15, 2003
15.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
16.	Evidence for age-dependent impairment of antiviral 2',5'-oligoadenylate synthetase/ribonuclease L-system in tissues of rat.	Pfeifer K, etal., Mech Ageing Dev. 1993 Feb;67(1-2):101-14.
17.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
18.	GOA pipeline	RGD automated data pipeline
19.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
20.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
21.	Roles of vaccinia virus genes E3L and K3L and host genes PKR and RNase L during intratracheal infection of C57BL/6 mice.	Rice AD, etal., J Virol. 2011 Jan;85(1):550-67. doi: 10.1128/JVI.00254-10. Epub 2010 Oct 13.
22.	PKR and RNase L contribute to protection against lethal West Nile Virus infection by controlling early viral spread in the periphery and replication in neurons.	Samuel MA, etal., J Virol. 2006 Jul;80(14):7009-19. doi: 10.1128/JVI.00489-06.
23.	Lack of association between RNASEL Arg462Gln variant and the risk of breast cancer.	Sevinc A, etal., Anticancer Res. 2004 Jul-Aug;24(4):2547-9.
24.	Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation.	Thornbrough JM, etal., mBio. 2016 Mar 29;7(2):e00258. doi: 10.1128/mBio.00258-16.
25.	Blockade of interferon induction and action by the E3L double-stranded RNA binding proteins of vaccinia virus.	Xiang Y, etal., J Virol. 2002 May;76(10):5251-9. doi: 10.1128/jvi.76.10.5251-5259.2002.
26.	Role of ribonuclease L in viral pathogen-associated molecular pattern/influenza virus and cigarette smoke-induced inflammation and remodeling.	Zhou Y, etal., J Immunol. 2013 Sep 1;191(5):2637-46. doi: 10.4049/jimmunol.1300082. Epub 2013 Aug 2.

Additional References at PubMed

PMID:7514601	PMID:12477932	PMID:19245366	PMID:19923450	PMID:22441668	PMID:24578532

Genomics

Comparative Map Data

Rnasel
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	68,446,641 - 68,460,804 (+)	NCBI		GRCr8
mRatBN7.2	13	65,894,990 - 65,910,354 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	65,901,459 - 65,908,704 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	68,502,520 - 68,509,768 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	69,792,702 - 69,799,948 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	67,049,541 - 67,056,829 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	71,188,712 - 71,202,636 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	71,192,142 - 71,202,625 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	76,153,998 - 76,167,666 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	68,822,013 - 68,829,264 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	68,836,092 - 68,843,336 (+)	NCBI
Celera	13	65,801,918 - 65,809,169 (+)	NCBI		Celera
Cytogenetic Map	13	q21	NCBI

RNASEL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	182,573,634 - 182,589,256 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	182,573,634 - 182,589,256 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	182,542,769 - 182,558,391 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	180,809,395 - 180,822,731 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	179,274,428 - 179,287,765	NCBI
Celera	1	155,654,005 - 155,667,341 (-)	NCBI		Celera
Cytogenetic Map	1	q25.3	NCBI
HuRef	1	153,779,235 - 153,794,860 (-)	NCBI		HuRef
CHM1_1	1	183,966,207 - 183,981,832 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	181,933,110 - 181,948,734 (-)	NCBI		T2T-CHM13v2.0

Rnasel
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	153,625,089 - 153,644,441 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	153,625,172 - 153,639,967 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	153,749,344 - 153,768,690 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	153,749,426 - 153,764,221 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	155,596,556 - 155,611,351 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	155,515,149 - 155,524,559 (+)	NCBI		MGSCv36	mm8
Celera	1	156,181,252 - 156,196,205 (+)	NCBI		Celera
Cytogenetic Map	1	G3	NCBI
cM Map	1	65.43	NCBI

Rnasel
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	21,411,980 - 21,425,052 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	21,413,950 - 21,424,860 (-)	NCBI	ChiLan1.0	ChiLan1.0

RNASEL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	67,139,920 - 67,155,657 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	66,823,513 - 66,839,195 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	158,092,346 - 158,108,026 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	161,744,169 - 161,759,741 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	161,741,645 - 161,760,045 (-)	Ensembl	panpan1.1		panPan2

RNASEL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	15,978,055 - 16,001,604 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	15,856,151 - 16,001,569 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	15,566,511 - 15,588,072 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	15,706,990 - 15,731,063 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	15,584,822 - 15,731,112 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	15,621,143 - 15,642,651 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	15,729,189 - 15,750,983 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	15,858,335 - 15,880,030 (-)	NCBI		UU_Cfam_GSD_1.0

Rnasel
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	89,316,525 - 89,330,595 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936481	7,165,353 - 7,177,538 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936481	7,165,400 - 7,177,342 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RNASEL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	123,893,294 - 123,910,398 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	123,895,045 - 123,910,386 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	136,210,085 - 136,224,410 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RNASEL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	46,779,221 - 46,795,854 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	46,779,700 - 46,795,842 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	47,997,591 - 48,013,734 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rnasel
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624814	11,268,698 - 11,305,221 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624814	11,268,725 - 11,319,023 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Rnasel
201 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	222
Count of miRNA genes:	162
Interacting mature miRNAs:	181
Transcripts:	ENSRNOT00000032157
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	101056920	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	5994833	77046787	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	5994833	77046787	Rat
1581570	Eae17	Experimental allergic encephalomyelitis QTL 17	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	8897350	101631289	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	20605871	101339738	Rat
61391	Bp5	Blood pressure QTL 5	5.6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	22301875	67301875	Rat
70170	Eae14	Experimental allergic encephalomyelitis QTL 14		0.0024	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	23203448	68203448	Rat
6893338	Cm76	Cardiac mass QTL 76	0	0.99	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	23692969	68692969	Rat
1558644	Cm45	Cardiac mass QTL 45	3.6	0.002	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	13	23692969	68692969	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	30395351	101056920	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	31241331	93395974	Rat
2303563	Bw89	Body weight QTL 89	6		body mass (VT:0001259)	body weight (CMO:0000012)	13	32284471	77284471	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	34535218	79535218	Rat
12879477	Bp401	Blood pressure QTL 401			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	37262092	82262092	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	37374509	82374509	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	37374509	82374509	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	37415584	80753406	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	37415584	82415584	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	38433408	83433408	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	39754544	84754544	Rat
12879444	Bp397	Blood pressure QTL 397			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45049404	90049404	Rat
12879471	Bp398	Blood pressure QTL 398			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45514719	90514719	Rat
12879441	Bp396	Blood pressure QTL 396			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45699983	90699983	Rat
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	46088046	91088046	Rat
71119	Thym2	Thymus enlargement QTL 2	3.8		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	13	46197976	84753113	Rat
1641901	Alcrsp6	Alcohol response QTL 6			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	13	52362171	97362171	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	56056920	101056920	Rat
2303028	Bp329	Blood pressure QTL 329			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	58497872	73485113	Rat
724564	Uae11	Urinary albumin excretion QTL 11	5.7		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	13	59492522	77046890	Rat
738026	Lnnr5	Liver neoplastic nodule remodeling QTL 5	3.29		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	59874408	85581182	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	61825626	106807694	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	65103704	106807694	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	65103704	106807694	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3		7		18				15		14	9
Low		41	50	41	1	41	8	11	59	35	24	2	8
Below cutoff		2									3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_182673	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249998	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006250000	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006250001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006250002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006250004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598841	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598842	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090867	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090868	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090869	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090870	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090871	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090872	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090873	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090874	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272421	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272423	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272424	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272425	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272426	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272427	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272428	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272429	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272430	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272431	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272432	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272433	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272434	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272435	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272436	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY262823	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC099212	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234633	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000032157 ⟹ ENSRNOP00000032975

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	65,901,459 - 65,908,704 (+)	Ensembl
Rnor_6.0 Ensembl	13	71,192,142 - 71,202,625 (+)	Ensembl

RefSeq Acc Id:

NM_182673 ⟹ NP_872614

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,451,911 - 68,459,162 (+)	NCBI
mRatBN7.2	13	65,901,461 - 65,908,712 (+)	NCBI
Rnor_6.0	13	71,193,743 - 71,200,994 (+)	NCBI
Rnor_5.0	13	76,153,998 - 76,167,666 (+)	NCBI
RGSC_v3.4	13	68,822,013 - 68,829,264 (+)	RGD
Celera	13	65,801,918 - 65,809,169 (+)	RGD

Sequence:

show sequence

TCATTGCTCAAGGAAAAGGCATTGACTATCATGGAGACCACGGATCATAGCACACCTCAGTGTG
GATCCGCATCAGCAGGTGGTCAGAAGACCGTTGGCAAAGATGATTATTTGTTGATAGAAGCTGT
TAACAAGGGAGATGCTGACAGGGTCCAGCAATTGTTAGAACAAGGGGCTGATGCCAATGTCTGT
GAAGAATCTGGGGGCTGGACACCTTTGCACAACGCGGTGCAGTCTGGCAGGGTAGATATTGTGA
ATCTCCTGCTTCGTTATGGTGCTGACCCTCATCGGAGGAAGAAGAATGGGGCCACCCCCTTCAT
CGTTGCTGGGATCTGTGGAGATGTGAGTCTGCTCCAGATTTTCCTCTCTCGAGGTGCAAACATC
AATGAGCGTGACATGTACGGATTCACGGCTTTCATGGAAGCTGCTGAGTATGGTAACGTTGAAG
CCCTAAAATTCCTTTTTGCTGAAGGGGCCGATGTGAATTTGAGACGGGAGACAACGGAGGACAG
AAGGCGACTGAAGCAAGGAGGGGCCACGGCTCTCATGAGCGCTGCGGAGAATGGCCACCCGGAA
GTCGTGAGAATTCTCCTCGATGAAATGAAGGCAGAAGCCGATGCTCGGGACAATATGGGCAGAA
ATGCCTTGATCCGTTCTCTGCTGAACCGCGATTGTGAAAATGTTGAAATTCATGTGGAGGAGAT
CACTTCAGTTCTGATTCAATACGGCGCTGATATTAATGTGAGAGGGGAAGGTGAGAAGACACCT
CTGATCTCAGCAGTGAAGAGGAAGCACACAGGTTTGGTGCAGATGCTCCTGAGTCAGGAGGGCA
TAAAGGTGAATGACAGAGATAGCGAGGGCAAGACGGCGCTGCAAATTGCTGTTGAACTCAAACT
GAAGGAAATCGTCCGGTTGCTTCTTGAAAAGGGAGCCGATACCAAGTGTGGCGATCTTGTTTGG
ATAGCCAAGAGGAATTATGACCATGGTCTAGTAAAACTTCTTCTCTCGTATGAAGCTAATCACG
ACACCAACCCTCCTGCTAAAGACTGGTTGCCTCACAGTGCACGCTGGGGGGAGGCCTTGGAAAG
ACTCCACAGTGTGTCTCGACCCATGACTGGCAAACTCAAGATCTTCATGAATGATGACTATAAA
ATTGCCAGCACTTCTGAAGGGGGCATCTACCTAGGGATCTATGACAATCGAGAGGTGGCTGTGA
AGGTCTTCTGTGAGAATAGCTCACGTGGACGTAAGGAAGTCTCTTGTCTGCGGGACTGTGGAGA
CCACAGTAACTTACTGACTTTCTATGGAAGCGAGGAGCACAAGGGCAGTTTATATGTGTGTGTG
TCCCTGTGTGAGTCGACATTGGAAAAGTTCCTGAATGTGCCCAGAGAGGAACCTATGGAGAAAG
GGGAAGACAAGTTTGCCCTCAGTGTCCTATTGTCTATATTTAAGGGTGTTCAAAAACTACACAT
GCATGGATATTCCCATCAGAACCTGCAACCGCCAAACATCTTAATAGATTCTGAGAAAGCTGTC
CGGCTGGCAGATTTTGATGAGAGCATCCAGTGGATGAGAGAGTCACAGACGGTCCAGAGAGACT
TGGAGGACCTTGGACGACTGGTTCTCTATGTGGTAAACAAAGGTGAGATCCCCTTTGAGACACT
GAAGGGTCAGAATGATGAAGAATTGCTTACGATCGCTCCAAATGAGGAGACTAAGGACCTCGTT
CATTGCCTGTTTTCTCCTGGAGAAAATGTAAAGAACTGTCTGATGGACCTGCTTGGCCATCCTT
TCTTTTGGACTTGGGAGAACCGCTATAGAACGCTTCGGGATGTGGGAAATGAATCTGACATCAA
AGTACGAAATAATAAAAGTAAACTTCTCAAGCTACTGCAGCCTCAGACACACGCGCCTTCCAGA
AGCTTTGATCGGTGGACGTCTAAGATCGACAAACGTGTCATGTCTGACATGAATGGTTTCTATA
AATCCCGAAAGGGTTATCGGGATACTGTAGGTGATCTGCTGAAGTTTATTCGGAATATAGGAGA
ACACATCAATGAGGAAAAAAACAGGCAAATGAAGGAGATACTTGGAGACCCTTCTCGTTATTTT
CAGGAGACATTTCCAGATCTTGTAATCTATATCTACAAGAAACTAAAGGAAACGGAATTCAGAA
AACACTTTCCTCAGCCTCCACCAAGCCTCAGCGTGCCAGAGGCAGCGGGACCAGGGGGTGTACA
GAGCTGAGTCTTGAAAGTTCATGGGACCATTTCTTCCAGTCAGTATAGTTCTTGGCAAGTTTCA
CATTTCTGGTCTCTTAAGCAGCCTGGTTGCTGTGAGCACTTAGATAGCCAGTGTGTTGGTTTCT
GATGCAGTAAGTTCTACACATTTCCATGATCACAAAAGCAGTGTACTACAAAGCTATACTGCCC
CATTTTAGTGGATGGAATGGGGAGCGCCTTCTGTTAAGATTTTGTTTAAAAAAAAAAAAAAAAA
A

hide sequence

RefSeq Acc Id:

XM_006249999 ⟹ XP_006250061

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,653 - 68,460,804 (+)	NCBI
mRatBN7.2	13	65,895,007 - 65,910,354 (+)	NCBI
Rnor_6.0	13	71,188,712 - 71,202,636 (+)	NCBI
Rnor_5.0	13	76,153,998 - 76,167,666 (+)	NCBI

Sequence:

show sequence

CATGAGCAAAATTGCCCTGGAAGCTCGGCTCAGCGGCTGTTTGAATTACTTCCCGTGGACATAA
ACAGCCCGGCAGATGACAGCAGCAATTAGAGCCATCCCGTGATCGCGGTCCGGGGAACAAGACA
CAAACAAGAGAACTGGTAAGCACGACCAAAAGGAGCTGAATGTCGCCTCTGCTGGCTAGCCTGA
GTGACTGCTGCCTCTGAGGCGTCTAGCTCCCCTTTGTTTAGTCTGGTTCCTAGAAAACAACAGC
GAAAGTGGCCAGTGTGGAATTCATCTTGCTTCCAAACAGCATCGAGTCACTCCCGGATCTTTGT
TTCGTTGCACCTCAGATCATCTGAATAGCCCAAGCTTGTCAGGCTCAGGCAGGGGTCCGGAGAG
GAGGAGCAGTGAGTGTGGGGTGACCAGTCTCACCTAGGACAAAGAAAGCCAGATGGACAAAGTC
AAACAAATCCACTTGTCTTCCTAAAGGAGCTTGCACTCCCCACTACCCCCAGAAGCTGCCAGTT
ACTCGATGAGGTGTCAGAAGACAGAATATATCAGCCCAATTCCTACCGCAAGACTCTCTTTGTG
TCCCCAAGAAACGCACGTGTTCATTGCTCAAGGAAAAGGCATTGACTATCATGGAGACCACGGA
TCATAGCACACCTCAGTGTGGATCCGCATCAGCAGGTGGTCAGAAGACCGTTGGCAAAGATGAT
TATTTGTTGATAGAAGCTGTTAACAAGGGAGATGCTGACAGGGTCCAGCAATTGTTAGAACAAG
GGGCTGATGCCAATGTCTGTGAAGAATCTGGGGGCTGGACACCTTTGCACAACGCGGTGCAGTC
TGGCAGGGTAGATATTGTGAATCTCCTGCTTCGTTATGGTGCTGACCCTCATCGGAGGAAGAAG
AATGGGGCCACCCCCTTCATCATTGCTGGGATCTGTGGAGATGTGAGTCTGCTCCAGATTTTCC
TCTCTCGAGGTGCAAACATCAATGAGCGTGACATGCACGGATTCACGGCTTTCATGGAAGCTGC
TGAGTATGGTAACGTTGAAGCCCTAAAATTCCTTTTTGCTGAAGGGGCCGATGTGAATTTGAGA
CGGGAGACAACGGAGGACAGAAGGCGACTGAAGCAAGGAGGGGCCACGGCTCTCATGAGCGCTG
CGGAGAATGGCCACCCGGAAGTCGTGAGAATTCTCCTCGATGAAATGAAGGCAGAAGCCGATGC
TCGGGACAATATGGGCAGAAATGCCTTAATCCGTTCTCTGCTGAACCGCGATTGTGAAAATGTT
GAAATTCATGTGGAGGAGATCACTTCAGTTCTGATTCAATATGGCGCTGATATTAATGTGAGAG
GGGAAGGTGAGAAGACACCTCTGATCTCAGCAGTGGAGAGGAAGCACACAGGTTTGGTGCAGAT
GCTCCTGAGTCAGGAGGGCATAAAGGTGAATGACAGAGATAGCGAGGGCAAGACGGCGCTGCAA
ATTGCTGTTGAACTCAAACTGAAGGAAATCGTCCGGTTGCTTCTTGAAAAGGGAGCCGATACCA
AGTGTGGCGATCTTGTTTGGATAGCCAAGAGGAATTATGACCATGGTCTAGTAAAACTTCTTCT
CTCGTATGAAGCTAATCACGACACCAACCCTCCTGCTAAAGACTGGTTGCCTCACAGTGCACGC
TGGGGGGAGGACTTGAAAAGACTCCACAGTGTGTCTCGACCCATGATTGGCAAACTCAAGATCT
TCATGAATGATGCCTATAAAATTGCCAGCACTTCTGAAGGGGGCATCTACCTAGGGATCTATGA
CAATCGAGAGGTGGCTGTGAAGGTCTTCTGTGAGAATAGCTCACGTGGACGTAAGGAAGTCGCT
TGTCTGCGGGACTGTGGAGACCACAGTAACTTACTGACTTTCTATGGAAGCGAGGAGCACAAGG
GCAATTTATATGTGTGTGTGTCCCTGTGTGAGTCGACATTGGAAAAGTTCCTGAATGTGCCCAG
AGAGGAACCTATGGAGAAAGGGGAAGACAAGTTTGCCCTCAGTGTCCTATTGTCTATATTTAAG
GGTGTTCAAAAACTACACATGCATGGATATTCCCATCAGAACCTGCAACCGCCAAACATCTTAA
TAGATTCTGAGAAAGCTGTCCGGCTGGCAGATTTTGATGAGAGCATCCAGTGGATGAGAGAGTC
ACAGACGGTCCAGAGAGACTTGGAGGACCTTGGACGACTGGTTCTCTATGTGGTAAACAAAGGT
GAGATCCCCTTTGAGACACTGAAGGGTCAGAATGATGAAGAATTGCTTACGATCGCTCCAAATG
AGGAGACTAAGGACCTCGTTCATTGCCTGTTTTCTCCTGGAGAAAATGTAAAGAACTGTCTGAT
GGACCTGCTTGGCCATCCTTTCTTTTGGACTTGGGAGAACCGCTATAGAACGCTTCGGGATGTG
GGAAATGAATCTGACATCAAAGTACGAAATAATAAAAGTAAACTTCTCAAGCTACTGCAGCCTC
AGACACACGCGCCTTCCAGAAGCTTTGATCGGTGGACGTCTAAGATCGACAAACGTGTCATGTC
TGACATGAATGGTTTCTATAAATCCCGAAAGGGTTATCGGGATACTGTAGGTGATCTGCTGAAG
TTTATTCGGAATATAGGAGAACACATCAATGAGGAAAAAAACAGGCAAATGAAGGAGATACTTG
GAGACCCTTCTCGTTATTTTCAGGAGACATTTCCAGATCTTGTAATCTATATCTACAAGAAACT
AAAGGAAACGGAATTCAGAAAACACTTTCCTCAGCCTCCACCAAGCCTCAGCGTGCCAGAGGCA
GCGGGACCAGGGGGTGTACAGAGCTGAGTCTTGAAAGTTCATGGGACCATTTCTTCCAGTCAGT
ATAGTTCTTGGCAAGTTTCACATTTCTGGTCTCTTAAGCAGCCTGGTTGCTGTGAGCACTTAGA
TAGCCAGTATGTTGGTTTCTGATGCAGTAAGTTCTACACATTTCCATGATCACAAAAGCAGTGT
ACTACAAAGCTATACTGCCCCATTTTAGTGGATGGAATGGGGAGCGCCTTCTGTTAAGATTTTG
TTTAAAAAAAATTACGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCATGAGAGAGAGAGAGAGGG
GTGGGGGGAGAGGCAGACAGACAGACAGGAGAGAGGGGAGAGACTGACTGACTGACTAATTGTG
GAGTTGGTTTTCTCTTTCTACCTCTCTGTGGGTTCTGGGGATTGAACTTATGCTGTGAGGCTTA
TGTGGTAAGCATTTCTACTGAGTCATGCCCAGCAGCATGATTCCCATTTTCCCATGATTCCCGA
GATGTATATCAAGACTCCTATGGCTGTAAGTTTTATATTTATCTCATTTAATCCTTCCAGTGAG
CTTACAGAACAGAATTCATTGTCTCCCTTGAAGAACTGAGGCTCAGAGAATCTGAGTGACTTGC
CCAGGATCACAAAGCACTGTTTAAAAAAAAAAAAAAAAAGACACGATTTTATTGTCACCTCTCA
CATGGGGGCTTCATCCAGCATCTCTTCTGGATGAAATTCAGGAATAGGCCAACATATGCCAAAA
GGACTTCGTATTCGCTGGGTACTGTATATGTCTAGGCACCATCTAAATGAATTCCATTCCTTCT
GCGAGCATCTGTACTGGTGTCTCATGACTTCGAGGTTATAGTTCTCACTTGAAGTCGTTTATCA
GTGTCACGGCTGGGGGCGGGGAGATGGCACTACTGGCATTGAGTAAGGAGGAACCAGCGATGCC
AGCAAACATTCCAGTGATGCATGAGGCAGCTTCCCACAATGCCACACTAGGCACACTACGTATC
AGGGGTGCTGAGGCAGAGAAAGACTGTTCTGAGCTGGCCCTGGACCCAGGACTGTGGAGTGCAC
TGAACGCCCCCAGAAGAATGATGTGGGTGTCTTTTCTTGATGCTGGATCTGAAATGAAGCAACT
CCTTCTGGTGTCCACACAGGAGTCCTCACTTTCCCTCACTTCCCATGCTCCACGGGGCAATGAT
CCAACTGGGATACTCTCTCTAGTTCTCTGACACACGTCACCTCGGTGCAAACTTTATCCTTTTG
AGCTCCAGCCCTCCTCCAATCAAAGCCCTATCCTTAGGGCCTTTGTATCTTTACTGCTTAGTAA
AAACTTTGCTCTGTGACAATGCTTGATAAGTTTCCACTGAATAATCAATGGACAATCTTTGCAC
ATGTTCGACGACGATGATAAACCTTTAGTATTTACACATTATATGTACATGTTTTTAAATTTAA
TTTTGTTTTGAGAACAGTGCTGTAAGGCAAGCATGTGATCTTTATTTTGGCAATGAGGAAAGTA
AGGCTAGAAATATTTCTGTTTACTCTAGGCACATGGCATGGAGATTCACTACCTTGATTTGGAC
AGACTTTCTGGTGTGATATCTGATGTTCTTTTCACCTCTCATTGTGGTGACCAAGATGGCGCTT
TAGAATGGGAATTAAATGCTATCTTAGACTCCTTCCCAAAAGGAGGCATCTTGAAGCGAATAGG
TGCCTGTCACTGTAAGGAGTTAAGGCACGCTGGAAGAAACAGAGTAACGGCTTAAAGGATGGCA
TATTTAAAATTTAAAATTAAATGTTTTAAAATTGAGTTTTGTTGTCTGACTTGGATATGTCAAT
CAAAATGTCCATGTGTGAAGAATACTCAATAAAGATGGGAATCATTTCATTAA

hide sequence

RefSeq Acc Id:

XM_006250004 ⟹ XP_006250066

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,641 - 68,457,662 (+)	NCBI
mRatBN7.2	13	65,894,990 - 65,907,216 (+)	NCBI
Rnor_6.0	13	71,188,712 - 71,199,505 (+)	NCBI
Rnor_5.0	13	76,153,998 - 76,167,666 (+)	NCBI

Sequence:

show sequence

CATGAGCAAAATTGCCCTGGAAGCTCGGCTCAGCGGCTGTTTGAATTACTTCCCGTGGACATAA
ACAGCCCGGCAGATGACAGCAGCAATTAGAGCCATCCCGTGATCGCGGTCCGGGGAACAAGACA
CAAACAAGAGAACTGGTAAGCACGACCAAAAGGAGCTGAATGTCGCCTCTGCTGGCTAGCCTGA
GTGACTGCTGCCTCTGAGGCGTCTAGCTCCCCTTTGTTTAGTCTGGTTCCTAGAAAACAACAGC
GAAAGTGGCCAGTGTGGAATTCATCTTGCTTCCAAACAGCATCGAGTCACTCCCGGATCTTTGT
TTCGTTGCACCTCAGATCATCTGAATAGCCCAAGCTTGTCAGGCTCAGGCAGGGGTCCGGAGAG
GAGGAGCAGTGAGTGTGGGGTGACCAGTCTCACCTAGGACAAAGAAAGCCAGATGGACAAAGTC
AAACAAATCCACTTGTCTTCCTAAAGGAGCTTGCACTCCCCACTACCCCCAGAAGCTGCCAGTT
ACTCGATGAGGTGTCAGAAGACAGAATATATCAGCCCAATTCCTACCGCAAGACTCTCTTTGTG
TCCCCAAGAAACGCACGTGTTCATTGCTCAAGGAAAAGGCATTGACTATCATGGAGACCACGGA
TCATAGCACACCTCAGTGTGGATCCGCATCAGCAGGTGGTCAGAAGACCGTTGGCAAAGATGAT
TATTTGTTGATAGAAGCTGTTAACAAGGGAGATGCTGACAGGGTCCAGCAATTGTTAGAACAAG
GGGCTGATGCCAATGTCTGTGAAGAATCTGGGGGCTGGACACCTTTGCACAACGCGGTGCAGTC
TGGCAGGGTAGATATTGTGAATCTCCTGCTTCGTTATGGTGCTGACCCTCATCGGAGGAAGAAG
AATGGGGCCACCCCCTTCATCATTGCTGGGATCTGTGGAGATGTGAGTCTGCTCCAGATTTTCC
TCTCTCGAGGTGCAAACATCAATGAGCGTGACATGCACGGATTCACGGCTTTCATGGAAGCTGC
TGAGTATGGTAACGTTGAAGCCCTAAAATTCCTTTTTGCTGAAGGGGCCGATGTGAATTTGAGA
CGGGAGACAACGGAGGACAGAAGGCGACTGAAGCAAGGAGGGGCCACGGCTCTCATGAGCGCTG
CGGAGAATGGCCACCCGGAAGTCGTGAGAATTCTCCTCGATGAAATGAAGGCAGAAGCCGATGC
TCGGGACAATATGGGCAGAAATGCCTTAATCCGTTCTCTGCTGAACCGCGATTGTGAAAATGTT
GAAATTCATGTGGAGGAGATCACTTCAGTTCTGATTCAATATGGCGCTGATATTAATGTGAGAG
GGGAAGGTGAGAAGACACCTCTGATCTCAGCAGTGGAGAGGAAGCACACAGGTTTGGTGCAGAT
GCTCCTGAGTCAGGAGGGCATAAAGGTGAATGACAGAGATAGCGAGGGCAAGACGGCGCTGCAA
ATTGCTGTTGAACTCAAACTGAAGGAAATCGTCCGGTTGCTTCTTGAAAAGGGAGCCGATACCA
AGTGTGGCGATCTTGTTTGGATAGCCAAGAGGAATTATGACCATGGTCTAGTAAAACTTCTTCT
CTCGTATGAAGCTAATCACGACACCAACCCTCCTGCTAAAGACTGGTTGCCTCACAGTGCACGC
TGGGGGGAGGACTTGAAAAGACTCCACAGTGTGTCTCGACCCATGATTGGCAAACTCAAGATCT
TCATGAATGATGCCTATAAAATTGCCAGCACTTCTGAAGGGGGCATCTACCTAGGGATCTATGA
CAATCGAGAGGTGGCTGTGAAGGTCTTCTGTGAGAATAGCTCACGTGGACGTAAGGAAGTCGCT
TGTCTGCGGGACTGTGGAGACCACAGTAACTTACTGACTTTCTATGGAAGCGAGGAGCACAAGG
GCAATTTATATGTGTGTGTGTCCCTGTGTGAGTCGACATTGGAAAAGTTCCTGAATGTGCCCAG
AGAGGAACCTATGGAGAAAGGGGAAGACAAGTTTGCCCTCAGTGTCCTATTGTCTATATTTAAG
GGTGTTCAAAAACTACACATGCATGGATATTCCCATCAGAACCTGCAACCGCCAAACATCTTAA
TAGATTCTGAGAAAGCTGTCCGGCTGGCAGATTTTGATGAGAGCATCCAGTGGATGAGAGAGTC
ACAGACGGTCCAGAGAGACTTGGAGGACCTTGGACGACTGGTTCTCTATGTGGTAAACAAAGGT
GAGATCCCCTTTGAGACACTGAAGGGTCAGAATGATGAAGAATTGCTTACGATCGCTCCAAATG
AGGAGACTAAGGACCTCGTTCATTGCCTGTTTTCTCCTGGAGAAAATGTAAAGAACTGTCTGAT
GGACCTGCTTGGCCATCCTTTCTTTTGGACTTGGGAGAAAATGACCATGGTAGTTCTATCGTCC
TCAGCCGCTATAGAACGCTTCGGGATGTGGGAAATGAATCTGACATCAAAGTACGAAATAATAA
AAGTAAACTTCTCAAGCTACTGCAGCCTCAGACACACGCGCCTTCCAGAAGCTTTGATCGGTGG
ACGTCTAAGATCGACAAACGTGTCATGTCTGACATGAATGGTTTCTATAAATCCCGAAAGGGTT
ATCGGGATACTGTAGGTGATCTGCTGAAGTTTATTCGGAATATAGGAGAACACATCAATGAGGA
AAAAA

hide sequence

RefSeq Acc Id:

XM_039090867 ⟹ XP_038946795

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,644 - 68,460,804 (+)	NCBI
mRatBN7.2	13	65,894,993 - 65,910,354 (+)	NCBI

RefSeq Acc Id:

XM_039090868 ⟹ XP_038946796

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,447,254 - 68,460,804 (+)	NCBI
mRatBN7.2	13	65,899,148 - 65,910,354 (+)	NCBI

RefSeq Acc Id:

XM_039090869 ⟹ XP_038946797

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,450,169 - 68,460,804 (+)	NCBI
mRatBN7.2	13	65,899,781 - 65,910,354 (+)	NCBI

RefSeq Acc Id:

XM_039090870 ⟹ XP_038946798

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,644 - 68,460,804 (+)	NCBI
mRatBN7.2	13	65,894,993 - 65,910,354 (+)	NCBI

RefSeq Acc Id:

XM_039090871 ⟹ XP_038946799

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,449,863 - 68,460,804 (+)	NCBI
mRatBN7.2	13	65,899,413 - 65,910,354 (+)	NCBI

RefSeq Acc Id:

XM_039090872 ⟹ XP_038946800

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,641 - 68,460,804 (+)	NCBI
mRatBN7.2	13	65,894,991 - 65,910,354 (+)	NCBI

RefSeq Acc Id:

XM_039090873 ⟹ XP_038946801

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,642 - 68,460,804 (+)	NCBI
mRatBN7.2	13	65,894,991 - 65,910,354 (+)	NCBI

RefSeq Acc Id:

XM_039090874 ⟹ XP_038946802

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,642 - 68,460,804 (+)	NCBI
mRatBN7.2	13	65,894,991 - 65,910,354 (+)	NCBI

RefSeq Acc Id:

XM_063272421 ⟹ XP_063128491

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,644 - 68,460,804 (+)	NCBI

RefSeq Acc Id:

XM_063272423 ⟹ XP_063128493

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,644 - 68,460,804 (+)	NCBI

RefSeq Acc Id:

XM_063272424 ⟹ XP_063128494

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,447,254 - 68,460,804 (+)	NCBI

RefSeq Acc Id:

XM_063272425 ⟹ XP_063128495

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,447,003 - 68,460,804 (+)	NCBI

RefSeq Acc Id:

XM_063272426 ⟹ XP_063128496

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,653 - 68,460,804 (+)	NCBI

RefSeq Acc Id:

XM_063272427 ⟹ XP_063128497

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,447,255 - 68,460,804 (+)	NCBI

RefSeq Acc Id:

XM_063272428 ⟹ XP_063128498

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,653 - 68,460,804 (+)	NCBI

RefSeq Acc Id:

XM_063272429 ⟹ XP_063128499

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,653 - 68,460,804 (+)	NCBI

RefSeq Acc Id:

XM_063272430 ⟹ XP_063128500

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,450,193 - 68,460,804 (+)	NCBI

RefSeq Acc Id:

XM_063272431 ⟹ XP_063128501

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,653 - 68,460,804 (+)	NCBI

RefSeq Acc Id:

XM_063272432 ⟹ XP_063128502

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,447,255 - 68,460,804 (+)	NCBI

RefSeq Acc Id:

XM_063272433 ⟹ XP_063128503

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,449,863 - 68,460,804 (+)	NCBI

RefSeq Acc Id:

XM_063272434 ⟹ XP_063128504

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,651 - 68,460,804 (+)	NCBI

RefSeq Acc Id:

XM_063272435 ⟹ XP_063128505

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,651 - 68,460,804 (+)	NCBI

RefSeq Acc Id:

XM_063272436 ⟹ XP_063128506

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	68,446,650 - 68,460,804 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_872614	(Get FASTA)	NCBI Sequence Viewer
	XP_006250061	(Get FASTA)	NCBI Sequence Viewer
	XP_006250066	(Get FASTA)	NCBI Sequence Viewer
	XP_038946795	(Get FASTA)	NCBI Sequence Viewer
	XP_038946796	(Get FASTA)	NCBI Sequence Viewer
	XP_038946797	(Get FASTA)	NCBI Sequence Viewer
	XP_038946798	(Get FASTA)	NCBI Sequence Viewer
	XP_038946799	(Get FASTA)	NCBI Sequence Viewer
	XP_038946800	(Get FASTA)	NCBI Sequence Viewer
	XP_038946801	(Get FASTA)	NCBI Sequence Viewer
	XP_038946802	(Get FASTA)	NCBI Sequence Viewer
	XP_063128491	(Get FASTA)	NCBI Sequence Viewer
	XP_063128493	(Get FASTA)	NCBI Sequence Viewer
	XP_063128494	(Get FASTA)	NCBI Sequence Viewer
	XP_063128495	(Get FASTA)	NCBI Sequence Viewer
	XP_063128496	(Get FASTA)	NCBI Sequence Viewer
	XP_063128497	(Get FASTA)	NCBI Sequence Viewer
	XP_063128498	(Get FASTA)	NCBI Sequence Viewer
	XP_063128499	(Get FASTA)	NCBI Sequence Viewer
	XP_063128500	(Get FASTA)	NCBI Sequence Viewer
	XP_063128501	(Get FASTA)	NCBI Sequence Viewer
	XP_063128502	(Get FASTA)	NCBI Sequence Viewer
	XP_063128503	(Get FASTA)	NCBI Sequence Viewer
	XP_063128504	(Get FASTA)	NCBI Sequence Viewer
	XP_063128505	(Get FASTA)	NCBI Sequence Viewer
	XP_063128506	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAP22025	(Get FASTA)	NCBI Sequence Viewer
	EDM09538	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000032975
	ENSRNOP00000032975.3

RefSeq Acc Id:

NP_872614 ⟸ NM_182673

- UniProtKB:

Q80WM6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

METTDHSTPQCGSASAGGQKTVGKDDYLLIEAVNKGDADRVQQLLEQGADANVCEESGGWTPLH
NAVQSGRVDIVNLLLRYGADPHRRKKNGATPFIVAGICGDVSLLQIFLSRGANINERDMYGFTA
FMEAAEYGNVEALKFLFAEGADVNLRRETTEDRRRLKQGGATALMSAAENGHPEVVRILLDEMK
AEADARDNMGRNALIRSLLNRDCENVEIHVEEITSVLIQYGADINVRGEGEKTPLISAVKRKHT
GLVQMLLSQEGIKVNDRDSEGKTALQIAVELKLKEIVRLLLEKGADTKCGDLVWIAKRNYDHGL
VKLLLSYEANHDTNPPAKDWLPHSARWGEALERLHSVSRPMTGKLKIFMNDDYKIASTSEGGIY
LGIYDNREVAVKVFCENSSRGRKEVSCLRDCGDHSNLLTFYGSEEHKGSLYVCVSLCESTLEKF
LNVPREEPMEKGEDKFALSVLLSIFKGVQKLHMHGYSHQNLQPPNILIDSEKAVRLADFDESIQ
WMRESQTVQRDLEDLGRLVLYVVNKGEIPFETLKGQNDEELLTIAPNEETKDLVHCLFSPGENV
KNCLMDLLGHPFFWTWENRYRTLRDVGNESDIKVRNNKSKLLKLLQPQTHAPSRSFDRWTSKID
KRVMSDMNGFYKSRKGYRDTVGDLLKFIRNIGEHINEEKNRQMKEILGDPSRYFQETFPDLVIY
IYKKLKETEFRKHFPQPPPSLSVPEAAGPGGVQS

hide sequence

RefSeq Acc Id:	XP_006250061 ⟸ XM_006249999
- Peptide Label:	isoform X2
- UniProtKB:	G3V915 (UniProtKB/TrEMBL), A6ICV9 (UniProtKB/TrEMBL)
- Sequence:	show sequence METTDHSTPQCGSASAGGQKTVGKDDYLLIEAVNKGDADRVQQLLEQGADANVCEESGGWTPLH NAVQSGRVDIVNLLLRYGADPHRRKKNGATPFIIAGICGDVSLLQIFLSRGANINERDMHGFTA FMEAAEYGNVEALKFLFAEGADVNLRRETTEDRRRLKQGGATALMSAAENGHPEVVRILLDEMK AEADARDNMGRNALIRSLLNRDCENVEIHVEEITSVLIQYGADINVRGEGEKTPLISAVERKHT GLVQMLLSQEGIKVNDRDSEGKTALQIAVELKLKEIVRLLLEKGADTKCGDLVWIAKRNYDHGL VKLLLSYEANHDTNPPAKDWLPHSARWGEDLKRLHSVSRPMIGKLKIFMNDAYKIASTSEGGIY LGIYDNREVAVKVFCENSSRGRKEVACLRDCGDHSNLLTFYGSEEHKGNLYVCVSLCESTLEKF LNVPREEPMEKGEDKFALSVLLSIFKGVQKLHMHGYSHQNLQPPNILIDSEKAVRLADFDESIQ WMRESQTVQRDLEDLGRLVLYVVNKGEIPFETLKGQNDEELLTIAPNEETKDLVHCLFSPGENV KNCLMDLLGHPFFWTWENRYRTLRDVGNESDIKVRNNKSKLLKLLQPQTHAPSRSFDRWTSKID KRVMSDMNGFYKSRKGYRDTVGDLLKFIRNIGEHINEEKNRQMKEILGDPSRYFQETFPDLVIY IYKKLKETEFRKHFPQPPPSLSVPEAAGPGGVQS hide sequence

RefSeq Acc Id:

XP_006250066 ⟸ XM_006250004

- Peptide Label:

isoform X3

- Sequence:

show sequence

METTDHSTPQCGSASAGGQKTVGKDDYLLIEAVNKGDADRVQQLLEQGADANVCEESGGWTPLH
NAVQSGRVDIVNLLLRYGADPHRRKKNGATPFIIAGICGDVSLLQIFLSRGANINERDMHGFTA
FMEAAEYGNVEALKFLFAEGADVNLRRETTEDRRRLKQGGATALMSAAENGHPEVVRILLDEMK
AEADARDNMGRNALIRSLLNRDCENVEIHVEEITSVLIQYGADINVRGEGEKTPLISAVERKHT
GLVQMLLSQEGIKVNDRDSEGKTALQIAVELKLKEIVRLLLEKGADTKCGDLVWIAKRNYDHGL
VKLLLSYEANHDTNPPAKDWLPHSARWGEDLKRLHSVSRPMIGKLKIFMNDAYKIASTSEGGIY
LGIYDNREVAVKVFCENSSRGRKEVACLRDCGDHSNLLTFYGSEEHKGNLYVCVSLCESTLEKF
LNVPREEPMEKGEDKFALSVLLSIFKGVQKLHMHGYSHQNLQPPNILIDSEKAVRLADFDESIQ
WMRESQTVQRDLEDLGRLVLYVVNKGEIPFETLKGQNDEELLTIAPNEETKDLVHCLFSPGENV
KNCLMDLLGHPFFWTWEKMTMVVLSSSAAIERFGMWEMNLTSKYEIIKVNFSSYCSLRHTRLPE
ALIGGRLRSTNVSCLT

hide sequence

RefSeq Acc Id:

ENSRNOP00000032975 ⟸ ENSRNOT00000032157

RefSeq Acc Id:	XP_038946800 ⟸ XM_039090872
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038946801 ⟸ XM_039090873
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038946802 ⟸ XM_039090874
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038946795 ⟸ XM_039090867
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038946798 ⟸ XM_039090870
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038946796 ⟸ XM_039090868
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038946799 ⟸ XM_039090871
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038946797 ⟸ XM_039090869
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063128491 ⟸ XM_063272421
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063128493 ⟸ XM_063272423
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063128506 ⟸ XM_063272436
- Peptide Label:	isoform X2
- UniProtKB:	A6ICV9 (UniProtKB/TrEMBL), G3V915 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128504 ⟸ XM_063272434
- Peptide Label:	isoform X2
- UniProtKB:	A6ICV9 (UniProtKB/TrEMBL), G3V915 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128505 ⟸ XM_063272435
- Peptide Label:	isoform X2
- UniProtKB:	A6ICV9 (UniProtKB/TrEMBL), G3V915 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128496 ⟸ XM_063272426
- Peptide Label:	isoform X2
- UniProtKB:	A6ICV9 (UniProtKB/TrEMBL), G3V915 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128498 ⟸ XM_063272428
- Peptide Label:	isoform X2
- UniProtKB:	A6ICV9 (UniProtKB/TrEMBL), G3V915 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128499 ⟸ XM_063272429
- Peptide Label:	isoform X2
- UniProtKB:	A6ICV9 (UniProtKB/TrEMBL), G3V915 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128501 ⟸ XM_063272431
- Peptide Label:	isoform X2
- UniProtKB:	A6ICV9 (UniProtKB/TrEMBL), G3V915 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128495 ⟸ XM_063272425
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063128494 ⟸ XM_063272424
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063128497 ⟸ XM_063272427
- Peptide Label:	isoform X2
- UniProtKB:	A6ICV9 (UniProtKB/TrEMBL), G3V915 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128502 ⟸ XM_063272432
- Peptide Label:	isoform X2
- UniProtKB:	A6ICV9 (UniProtKB/TrEMBL), G3V915 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128503 ⟸ XM_063272433
- Peptide Label:	isoform X2
- UniProtKB:	A6ICV9 (UniProtKB/TrEMBL), G3V915 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128500 ⟸ XM_063272430
- Peptide Label:	isoform X2
- UniProtKB:	A6ICV9 (UniProtKB/TrEMBL), G3V915 (UniProtKB/TrEMBL)

Protein Domains

KEN Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3V915-F1-model_v2	AlphaFold	G3V915	1-738	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:727933	AgrOrtholog
BioCyc Gene	G2FUF-17876	BioCyc
Ensembl Genes	ENSRNOG00000027017	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000032157	ENTREZGENE
	ENSRNOT00000032157.5	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1440.180	UniProtKB/TrEMBL
	1.25.40.20	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Ankyrin_rpt	UniProtKB/TrEMBL
	Ankyrin_rpt-contain_sf	UniProtKB/TrEMBL
	KEN_RNase_activator	UniProtKB/TrEMBL
	KEN_sf	UniProtKB/TrEMBL
	Kinase-like_dom	UniProtKB/TrEMBL
	Prot_kinase_cat_dom	UniProtKB/TrEMBL
	RNase-L_RNase	UniProtKB/TrEMBL
KEGG Report	rno:359726	UniProtKB/TrEMBL
NCBI Gene	359726	ENTREZGENE
PANTHER	2-5A-DEPENDENT RIBONUCLEASE	UniProtKB/TrEMBL
	2-5A-DEPENDENT RIBONUCLEASE	UniProtKB/TrEMBL
Pfam	Ank	UniProtKB/TrEMBL
	Ank_2	UniProtKB/TrEMBL
	Pkinase	UniProtKB/TrEMBL
	Ribonuc_2-5A	UniProtKB/TrEMBL
PhenoGen	Rnasel	PhenoGen
PRINTS	ANKYRIN	UniProtKB/TrEMBL
PROSITE	ANK_REP_REGION	UniProtKB/TrEMBL
	ANK_REPEAT	UniProtKB/TrEMBL
	KEN	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000027017	RatGTEx
SMART	ANK	UniProtKB/TrEMBL
	PUG	UniProtKB/TrEMBL
	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	ANK	UniProtKB/TrEMBL
	Kinase_like	UniProtKB/TrEMBL
UniProt	A6ICV9	ENTREZGENE, UniProtKB/TrEMBL
	G3V915	ENTREZGENE, UniProtKB/TrEMBL
	Q80WM6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-03	Rnasel	ribonuclease L	Rnasel	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Rnasel	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)		ribonuclease L (2, 5-oligoisoadenylate synthetase-dependent)	Name updated	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)