Gene: Rnasel (ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent))  Mus musculus

Symbol: Rnasel
Name: ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
Description: ENCODES a protein that exhibits ribonuclease activity (ortholog); RNA binding (ortholog); rRNA binding (ortholog); INVOLVED IN defense response to virus (ortholog); negative regulation of viral genome replication (ortholog); positive regulation of transcription from RNA polymerase II promoter (ortholog); PARTICIPATES IN hepatitis C virus infection pathway; influenza A virus infection pathway; ASSOCIATED WITH abnormal thymus morphology; decreased T cell apoptosis; enlarged thymus; ASSOCIATED WITH Colorectal Neoplasms, Hereditary Nonpolyposis (ortholog); Prostate cancer, familial (ortholog); PROSTATE CANCER, HEREDITARY, 1 (ortholog); FOUND IN nuclear matrix (ortholog); INTERACTS WITH dibutyl phthalate; pirinixic acid; S-adenosyl-L-methionine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2-5A-dependent ribonuclease; 2-5A-dependent RNAase; 2-5A-dependent RNase; E230029I04Rik; ribonuclease 4; RNase L
Orthologs: Homo sapiens : RNASEL (ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent))  HGNC
Rattus norvegicus : Rnasel (ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent))
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm381153,749,426 - 153,764,221+NCBI
Mouse cM Map1 +NCBI
Mouse Celera Assembly1156,181,252 - 156,196,205+NCBI
Mouse Genome Assembly Build 371155,596,556 - 155,611,351+NCBI
Mouse Genome Assembly Build 36.11155,600,061 - 155,609,471+NCBI
Mouse Cytogenetic Map1 G2 NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rnasel
Entrez Gene
Ensembl Gene
Genome Browser
MGI Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1553469
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2013-03-06
Status: ACTIVE