Nap1l1 (nucleosome assembly protein 1-like 1) - Rat Genome Database

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Gene: Nap1l1 (nucleosome assembly protein 1-like 1) Rattus norvegicus
Analyze
Symbol: Nap1l1
Name: nucleosome assembly protein 1-like 1
RGD ID: 71094
Description: Enables kinase binding activity. Involved in Schwann cell proliferation and cellular response to peptide hormone stimulus. Predicted to be located in cytoplasm. Predicted to be active in chromatin and nucleus. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human NAP1L1 (nucleosome assembly protein 1 like 1); PARTICIPATES IN histone modification pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC72278; NAP-1-related protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8748,819,464 - 48,844,108 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl748,819,477 - 48,844,104 (+)EnsemblGRCr8
mRatBN7.2746,933,278 - 46,957,853 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl746,933,356 - 46,956,593 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx748,833,036 - 48,856,337 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0751,036,091 - 51,059,392 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0750,813,953 - 50,837,254 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0754,213,305 - 54,237,880 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl754,213,319 - 54,236,625 (+)Ensemblrn6Rnor6.0
Rnor_5.0754,238,038 - 54,262,614 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4750,506,870 - 50,530,177 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera743,730,965 - 43,754,274 (+)NCBICelera
RGSC_v3.1750,527,406 - 50,550,142 (+)NCBI
Cytogenetic Map7q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
2-bromohexadecanoic acid  (ISO)
2-methylcholine  (ISO)
2-nitrofluorene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
Brodifacoum  (EXP)
Butylbenzyl phthalate  (ISO)
butyric acid  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
clofibrate  (EXP)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
disodium selenite  (ISO)
diuron  (EXP,ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
finasteride  (EXP)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
GSK-J4  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
L-ethionine  (EXP)
L-methionine  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
Monobutylphthalate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
nimesulide  (EXP)
nitrates  (ISO)
Nutlin-3  (ISO)
omeprazole  (EXP)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorooctanoic acid  (EXP)
permethrin  (EXP)
phenobarbital  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
pyrogallol  (ISO)
rimonabant  (ISO)
SB 431542  (ISO)
sevoflurane  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
triphenyl phosphate  (EXP,ISO)
uranium atom  (ISO)
ursodeoxycholic acid  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (IBA)
chromosome  (IEA)
cytoplasm  (IEA,ISO)
melanosome  (IEA)
nucleus  (IBA,IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Histone chaperones in nucleosome assembly and human disease. Burgess RJ and Zhang Z, Nat Struct Mol Biol. 2013 Jan;20(1):14-22. doi: 10.1038/nsmb.2461.
2. Rat NAP1: cDNA cloning and upregulation by Mpl ligand. Cataldo LM, etal., Gene. 1999 Jan 21;226(2):355-64.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Comparison in the biological characteristics between primary cultured sensory and motor Schwann cells. He Q, etal., Neurosci Lett. 2012 Jul 11;521(1):57-61. doi: 10.1016/j.neulet.2012.05.059. Epub 2012 May 30.
6. The role of genetic markers--NAP1L1, MAGE-D2, and MTA1--in defining small-intestinal carcinoid neoplasia. Kidd M, etal., Ann Surg Oncol. 2006 Feb;13(2):253-62. Epub 2006 Jan 20.
7. Characterisation of tumour-associated antigens in colon cancer. Line A, etal., Cancer Immunol Immunother. 2002 Nov;51(10):574-82. Epub 2002 Sep 19.
8. Genetic differentiation of appendiceal tumor malignancy: a guide for the perplexed. Modlin IM, etal., Ann Surg. 2006 Jul;244(1):52-60.
9. Transcriptional profiling in hepatoblastomas using high-density oligonucleotide DNA array. Nagata T, etal., Cancer Genet Cytogenet. 2003 Sep;145(2):152-60.
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. A mechanistic role for the chromatin modulator, NAP1L1, in pancreatic neuroendocrine neoplasm proliferation and metastases. Schimmack S, etal., Epigenetics Chromatin. 2014 Jul 21;7:15. doi: 10.1186/1756-8935-7-15. eCollection 2014.
15. Molecular characterization of hNRP, a cDNA encoding a human nucleosome-assembly-protein-I-related gene product involved in the induction of cell proliferation. Simon HU, etal., Biochem J 1994 Jan 15;297 ( Pt 2):389-97.
16. Cellular expression and localization of DGKzeta-interacting NAP1-like proteins in the brain and functional implications under hypoxic stress. Takahashi N, etal., Histochem Cell Biol. 2014 Nov;142(5):461-71. doi: 10.1007/s00418-014-1226-x. Epub 2014 Jun 4.
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:12947022   PMID:19946888   PMID:22681889   PMID:22871113   PMID:25931508   PMID:29209909   PMID:29490266   PMID:31505169   PMID:35352799  


Genomics

Comparative Map Data
Nap1l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8748,819,464 - 48,844,108 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl748,819,477 - 48,844,104 (+)EnsemblGRCr8
mRatBN7.2746,933,278 - 46,957,853 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl746,933,356 - 46,956,593 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx748,833,036 - 48,856,337 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0751,036,091 - 51,059,392 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0750,813,953 - 50,837,254 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0754,213,305 - 54,237,880 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl754,213,319 - 54,236,625 (+)Ensemblrn6Rnor6.0
Rnor_5.0754,238,038 - 54,262,614 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4750,506,870 - 50,530,177 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera743,730,965 - 43,754,274 (+)NCBICelera
RGSC_v3.1750,527,406 - 50,550,142 (+)NCBI
Cytogenetic Map7q22NCBI
NAP1L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381276,036,585 - 76,084,685 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1276,032,987 - 76,085,261 (-)Ensemblhg38GRCh38
GRCh371276,430,365 - 76,478,465 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361274,726,221 - 74,764,717 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341274,726,224 - 74,764,717NCBI
Celera1276,105,836 - 76,145,881 (-)NCBICelera
Cytogenetic Map12q21.2NCBI
HuRef1273,488,713 - 73,528,719 (-)NCBIHuRef
CHM1_11276,404,610 - 76,444,687 (-)NCBICHM1_1
T2T-CHM13v2.01276,011,669 - 76,059,726 (-)NCBIT2T-CHM13v2.0
Nap1l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910111,308,754 - 111,334,011 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10111,309,084 - 111,334,011 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3810111,472,882 - 111,498,150 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10111,473,223 - 111,498,150 (+)Ensemblmm10GRCm38
MGSCv3710110,910,248 - 110,935,206 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3610110,884,727 - 110,902,252 (+)NCBIMGSCv36mm8
Celera10113,416,423 - 113,441,366 (+)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1058.67NCBI
Nap1l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540515,330,328 - 15,365,208 (-)Ensembl
ChiLan1.0NW_00495540515,332,696 - 15,365,181 (-)NCBIChiLan1.0ChiLan1.0
NAP1L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21084,067,377 - 84,105,885 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11284,063,769 - 84,102,199 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01273,549,887 - 73,589,621 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11276,402,906 - 76,441,815 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1276,402,906 - 76,441,815 (-)EnsemblpanPan2panpan1.1
NAP1L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11519,141,803 - 19,175,576 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1519,143,284 - 19,175,581 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1519,624,067 - 19,659,864 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01519,478,079 - 19,513,939 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1519,477,927 - 19,514,525 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11519,080,341 - 19,116,126 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01519,136,918 - 19,172,670 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01519,266,054 - 19,301,904 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nap1l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494541,277,724 - 41,313,258 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365684,419,652 - 4,440,608 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365684,416,225 - 4,440,566 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAP1L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl539,328,052 - 39,363,711 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1539,329,628 - 39,363,699 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2542,892,559 - 42,926,668 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NAP1L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11171,639,965 - 71,679,131 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1171,522,837 - 71,678,825 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037173,870,263 - 173,909,998 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nap1l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475021,966,021 - 22,005,480 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Nap1l1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11189,652,383 - 189,676,877 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nap1l1
179 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:90
Count of miRNA genes:70
Interacting mature miRNAs:85
Transcripts:ENSRNOT00000005286
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)72154197751639954Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72380760668807606Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74511390390113903Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72663805771638057Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73984590284845902Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)72154197751639954Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73299870277998702Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73617876481178764Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74847504993475049Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73617876481178764Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74299622658678836Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72862457565788017Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71746044762460447Rat
2303582Gluco53Glucose level QTL 533blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)74860308793603087Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)72005723265057232Rat
61439Cia8Collagen induced arthritis QTL 85.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)72718291472182914Rat

Markers in Region
RH138744  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8748,840,303 - 48,840,896 (+)Marker Load Pipeline
mRatBN7.2746,954,046 - 46,954,639 (+)MAPPERmRatBN7.2
Rnor_6.0754,234,074 - 54,234,666NCBIRnor6.0
Rnor_5.0754,258,808 - 54,259,400UniSTSRnor5.0
RGSC_v3.4750,527,625 - 50,528,217UniSTSRGSC3.4
Celera743,751,722 - 43,752,314UniSTS
Cytogenetic Map7q21UniSTS
RH134582  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0754,260,929 - 54,261,143NCBIRnor5.0
RGSC_v3.4750,529,747 - 50,529,960UniSTSRGSC3.4
Celera743,753,844 - 43,754,057UniSTS
Cytogenetic Map7q21UniSTS
D14S655E  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2746,955,081 - 46,956,484 (+)MAPPERmRatBN7.2
Rnor_6.0754,235,109 - 54,236,511NCBIRnor6.0
Rnor_5.0754,259,843 - 54,261,245UniSTSRnor5.0
RGSC_v3.4750,528,660 - 50,530,062UniSTSRGSC3.4
Celera743,752,757 - 43,754,159UniSTS
Cytogenetic Map7q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000005286   ⟹   ENSRNOP00000005286
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl748,819,513 - 48,844,104 (+)Ensembl
mRatBN7.2 Ensembl746,933,375 - 46,956,591 (+)Ensembl
Rnor_6.0 Ensembl754,213,319 - 54,236,625 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106121   ⟹   ENSRNOP00000090697
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl748,819,555 - 48,842,842 (+)Ensembl
mRatBN7.2 Ensembl746,933,371 - 46,956,593 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109635   ⟹   ENSRNOP00000086824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl746,945,660 - 46,956,593 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109944   ⟹   ENSRNOP00000087774
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl748,819,477 - 48,842,855 (+)Ensembl
mRatBN7.2 Ensembl746,933,360 - 46,956,591 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114091   ⟹   ENSRNOP00000095957
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl746,933,356 - 46,954,898 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115155   ⟹   ENSRNOP00000086168
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl748,832,351 - 48,841,423 (+)Ensembl
mRatBN7.2 Ensembl746,946,094 - 46,955,166 (+)Ensembl
RefSeq Acc Id: NM_053561   ⟹   NP_446013
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8748,819,549 - 48,842,856 (+)NCBI
mRatBN7.2746,933,292 - 46,956,599 (+)NCBI
Rnor_6.0754,213,319 - 54,236,626 (+)NCBI
Rnor_5.0754,238,038 - 54,262,614 (+)NCBI
RGSC_v3.4750,506,870 - 50,530,177 (+)RGD
Celera743,730,965 - 43,754,274 (+)RGD
Sequence:
RefSeq Acc Id: XM_006241342   ⟹   XP_006241404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8748,819,464 - 48,844,108 (+)NCBI
mRatBN7.2746,933,278 - 46,957,853 (+)NCBI
Rnor_6.0754,213,305 - 54,237,880 (+)NCBI
Rnor_5.0754,238,038 - 54,262,614 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006241343   ⟹   XP_006241405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8748,819,464 - 48,841,159 (+)NCBI
mRatBN7.2746,933,278 - 46,954,902 (+)NCBI
Rnor_6.0754,213,305 - 54,234,929 (+)NCBI
Rnor_5.0754,238,038 - 54,262,614 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006241344   ⟹   XP_006241406
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8748,819,522 - 48,844,108 (+)NCBI
mRatBN7.2746,933,283 - 46,957,853 (+)NCBI
Rnor_6.0754,213,374 - 54,237,880 (+)NCBI
Rnor_5.0754,238,038 - 54,262,614 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063264353   ⟹   XP_063120423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8748,819,523 - 48,844,108 (+)NCBI
RefSeq Acc Id: XM_063264354   ⟹   XP_063120424
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8748,819,523 - 48,841,159 (+)NCBI
RefSeq Acc Id: NP_446013   ⟸   NM_053561
- UniProtKB: Q9Z2G8 (UniProtKB/Swiss-Prot),   A6IGG5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241404   ⟸   XM_006241342
- Peptide Label: isoform X1
- UniProtKB: Q9Z2G8 (UniProtKB/Swiss-Prot),   A6IGG5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241405   ⟸   XM_006241343
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AKV9 (UniProtKB/TrEMBL),   A6IGG9 (UniProtKB/TrEMBL),   A6IGH0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241406   ⟸   XM_006241344
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AE93 (UniProtKB/TrEMBL),   A6IGG8 (UniProtKB/TrEMBL),   A0A8I6A4K3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005286   ⟸   ENSRNOT00000005286
Ensembl Acc Id: ENSRNOP00000090697   ⟸   ENSRNOT00000106121
Ensembl Acc Id: ENSRNOP00000095957   ⟸   ENSRNOT00000114091
Ensembl Acc Id: ENSRNOP00000087774   ⟸   ENSRNOT00000109944
Ensembl Acc Id: ENSRNOP00000086824   ⟸   ENSRNOT00000109635
Ensembl Acc Id: ENSRNOP00000086168   ⟸   ENSRNOT00000115155
RefSeq Acc Id: XP_063120423   ⟸   XM_063264353
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A4K3 (UniProtKB/TrEMBL),   A0A8I6AE93 (UniProtKB/TrEMBL),   A6IGG8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120424   ⟸   XM_063264354
- Peptide Label: isoform X4
- UniProtKB: A6IGH0 (UniProtKB/TrEMBL)

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695190
Promoter ID:EPDNEW_R5715
Type:initiation region
Name:Nap1l1_1
Description:nucleosome assembly protein 1-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0754,213,318 - 54,213,378EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:71094 AgrOrtholog
BioCyc Gene G2FUF-34123 BioCyc
Ensembl Genes ENSRNOG00000003890 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000005286 ENTREZGENE
  ENSRNOT00000106121 ENTREZGENE
  ENSRNOT00000109944 ENTREZGENE
  ENSRNOT00000115155 ENTREZGENE
Gene3D-CATH 1.20.5.1500 UniProtKB/Swiss-Prot
  Nucleosome assembly protein UniProtKB/Swiss-Prot
InterPro NAP-like_sf UniProtKB/Swiss-Prot
  NAP_family UniProtKB/Swiss-Prot
KEGG Report rno:89825 UniProtKB/Swiss-Prot
NCBI Gene 89825 ENTREZGENE
PANTHER PTHR11875 UniProtKB/Swiss-Prot
Pfam NAP UniProtKB/Swiss-Prot
PhenoGen Nap1l1 PhenoGen
RatGTEx ENSRNOG00000003890 RatGTEx
Superfamily-SCOP SSF143113 UniProtKB/Swiss-Prot
UniProt A0A8I6A4K3 ENTREZGENE
  A0A8I6A6I2_RAT UniProtKB/TrEMBL
  A0A8I6AE93 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AKV9 ENTREZGENE
  A0A8I6GEN3_RAT UniProtKB/TrEMBL
  A6IGG5 ENTREZGENE, UniProtKB/TrEMBL
  A6IGG8 ENTREZGENE, UniProtKB/TrEMBL
  A6IGG9 ENTREZGENE, UniProtKB/TrEMBL
  A6IGH0 ENTREZGENE, UniProtKB/TrEMBL
  G3V6H9_RAT UniProtKB/TrEMBL
  NP1L1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-07-09 Nap1l1  nucleosome assembly protein 1-like 1      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference