Decr1 (2,4-dienoyl-CoA reductase 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Decr1 (2,4-dienoyl-CoA reductase 1) Rattus norvegicus
Analyze
Symbol: Decr1
Name: 2,4-dienoyl-CoA reductase 1
RGD ID: 70999
Description: Predicted to enable 2,4-dienoyl-CoA reductase (NADPH) activity; NADPH binding activity; and identical protein binding activity. Predicted to be involved in fatty acid beta-oxidation and positive regulation of cold-induced thermogenesis. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of catalytic complex. Predicted to be active in mitochondrion. Orthologous to human DECR1 (2,4-dienoyl-CoA reductase 1); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2,4-dienoyl CoA reductase 1, mitochondrial; 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial; 2,4-dienoyl-CoA reductase, mitochondrial; 4-enoyl-CoA reductase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8534,208,195 - 34,236,074 (-)NCBIGRCr8
mRatBN7.2529,411,172 - 29,439,054 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl529,411,172 - 29,439,018 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx531,567,474 - 31,595,241 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0533,160,140 - 33,187,907 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0533,120,325 - 33,148,092 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0529,573,893 - 29,601,731 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl529,573,898 - 29,601,748 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0534,253,236 - 34,280,749 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4530,492,196 - 30,520,172 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1530,492,195 - 30,520,172 (-)NCBI
Celera528,616,707 - 28,644,572 (-)NCBICelera
Cytogenetic Map5q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (EXP)
2-methylcholine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
actinomycin D  (ISO)
alpha-Zearalanol  (EXP)
amiodarone  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
azoxystrobin  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (EXP,ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
diclofenac  (EXP)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
farnesol  (ISO)
fenofibrate  (EXP,ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gemfibrozil  (EXP)
glutathione  (EXP)
GW 4064  (ISO)
indometacin  (ISO)
inulin  (ISO)
ivermectin  (ISO)
L-ethionine  (EXP)
L-methionine  (ISO)
leflunomide  (EXP)
limonene  (EXP)
methapyrilene  (EXP)
methidathion  (ISO)
methimazole  (EXP)
Muraglitazar  (EXP)
N-nitrosomorpholine  (EXP)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
niclosamide  (ISO)
nimesulide  (EXP)
nitrofen  (EXP)
Nutlin-3  (ISO)
oleic acid  (ISO)
omeprazole  (EXP)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenformin  (EXP)
phenobarbital  (EXP)
picrotoxin  (EXP)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
pravastatin  (EXP,ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (EXP)
Soman  (EXP)
streptozocin  (EXP)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
Tesaglitazar  (EXP)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (EXP)
vinclozolin  (EXP)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
catalytic complex  (IEA,ISO)
cytosol  (IEA,ISO)
mitochondrion  (IBA,IEA,ISO)
nucleoplasm  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. cDNA cloning of rat liver 2,4-dienoyl-CoA reductase. Hirose A, etal., Biochim Biophys Acta 1990 Jul 30;1049(3):346-9.
4. Gene Data Set MGD Curation, June 12, 2002
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis. Miinalainen IJ, etal., PLoS Genet. 2009 Jul;5(7):e1000543. doi: 10.1371/journal.pgen.1000543. Epub 2009 Jul 3.
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. GOA pipeline RGD automated data pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:14651853   PMID:15489334   PMID:15531764   PMID:17636013   PMID:18614015   PMID:21630459   PMID:23376485   PMID:23486364   PMID:26316108   PMID:31505169  


Genomics

Comparative Map Data
Decr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8534,208,195 - 34,236,074 (-)NCBIGRCr8
mRatBN7.2529,411,172 - 29,439,054 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl529,411,172 - 29,439,018 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx531,567,474 - 31,595,241 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0533,160,140 - 33,187,907 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0533,120,325 - 33,148,092 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0529,573,893 - 29,601,731 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl529,573,898 - 29,601,748 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0534,253,236 - 34,280,749 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4530,492,196 - 30,520,172 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1530,492,195 - 30,520,172 (-)NCBI
Celera528,616,707 - 28,644,572 (-)NCBICelera
Cytogenetic Map5q13NCBI
DECR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38890,001,477 - 90,053,633 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl890,001,405 - 90,053,633 (+)EnsemblGRCh38hg38GRCh38
GRCh37891,013,705 - 91,065,861 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36891,082,756 - 91,133,403 (+)NCBINCBI36Build 36hg18NCBI36
Build 34891,082,755 - 91,133,403NCBI
Celera887,208,502 - 87,259,149 (+)NCBICelera
Cytogenetic Map8q21.3NCBI
HuRef886,223,894 - 86,274,542 (+)NCBIHuRef
CHM1_1891,054,504 - 91,105,151 (+)NCBICHM1_1
T2T-CHM13v2.0891,125,148 - 91,177,304 (+)NCBIT2T-CHM13v2.0
Decr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39415,917,240 - 15,945,377 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl415,917,240 - 15,945,507 (-)EnsemblGRCm39 Ensembl
GRCm38415,917,240 - 15,945,377 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl415,917,240 - 15,945,507 (-)EnsemblGRCm38mm10GRCm38
MGSCv37415,844,387 - 15,872,654 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36415,844,387 - 15,872,654 (-)NCBIMGSCv36mm8
Celera415,720,515 - 15,748,774 (-)NCBICelera
Cytogenetic Map4A2NCBI
cM Map46.66NCBI
Decr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554176,893,231 - 6,931,754 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554176,893,231 - 6,931,754 (+)NCBIChiLan1.0ChiLan1.0
DECR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27107,394,558 - 107,461,629 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1882,934,216 - 83,001,276 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0886,690,816 - 86,755,379 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1888,642,676 - 88,693,224 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl888,642,172 - 88,693,224 (+)Ensemblpanpan1.1panPan2
DECR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12935,495,348 - 35,544,955 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2935,495,261 - 35,544,955 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2935,646,866 - 35,697,851 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02935,692,661 - 35,742,310 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2935,692,704 - 35,744,794 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12935,684,839 - 35,729,541 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02935,703,896 - 35,747,852 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02936,138,067 - 36,183,640 (+)NCBIUU_Cfam_GSD_1.0
Decr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530343,936,906 - 43,975,997 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365443,816,653 - 3,853,632 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365443,816,543 - 3,853,288 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DECR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl446,731,360 - 46,767,422 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1446,731,359 - 46,767,427 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2451,207,727 - 51,243,866 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DECR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1885,086,843 - 85,129,267 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl885,086,874 - 85,129,160 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603955,747,223 - 55,792,311 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Decr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247441,963,825 - 2,003,643 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247441,965,605 - 2,003,299 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Decr1
441 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:100
Count of miRNA genes:87
Interacting mature miRNAs:90
Transcripts:ENSRNOT00000011330
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)5894822853948228Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5384401847869213Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
2312562Pur18Proteinuria QTL 182.60.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)5213896532656739Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
61462Niddm10Non-insulin dependent diabetes mellitus QTL 103.90.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)5511215947171491Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51268928557689285Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
1549901Neudeg2Neurodegradation QTL 240nervous system integrity trait (VT:0010566)mononuclear cell count (CMO:0002119)52483871044045280Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_057197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC108261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO385941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D00569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000011330   ⟹   ENSRNOP00000011330
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl529,411,172 - 29,439,011 (-)Ensembl
Rnor_6.0 Ensembl529,573,898 - 29,601,748 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097769   ⟹   ENSRNOP00000086268
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl529,411,172 - 29,439,011 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119084   ⟹   ENSRNOP00000093824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl529,411,203 - 29,439,018 (-)Ensembl
RefSeq Acc Id: NM_057197   ⟹   NP_476545
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8534,208,195 - 34,236,033 (-)NCBI
mRatBN7.2529,411,172 - 29,439,011 (-)NCBI
Rnor_6.0529,573,893 - 29,601,731 (-)NCBI
Rnor_5.0534,253,236 - 34,280,749 (-)NCBI
RGSC_v3.4530,492,196 - 30,520,172 (-)RGD
Celera528,616,707 - 28,644,572 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039109166   ⟹   XP_038965094
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8534,208,203 - 34,236,074 (-)NCBI
mRatBN7.2529,411,180 - 29,439,054 (-)NCBI
RefSeq Acc Id: XM_063287086   ⟹   XP_063143156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8534,209,028 - 34,236,074 (-)NCBI
RefSeq Acc Id: NP_476545   ⟸   NM_057197
- Peptide Label: precursor
- UniProtKB: Q6PCV4 (UniProtKB/Swiss-Prot),   Q64591 (UniProtKB/Swiss-Prot),   G3V734 (UniProtKB/TrEMBL),   A6IIA8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011330   ⟸   ENSRNOT00000011330
RefSeq Acc Id: XP_038965094   ⟸   XM_039109166
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000086268   ⟸   ENSRNOT00000097769
Ensembl Acc Id: ENSRNOP00000093824   ⟸   ENSRNOT00000119084
RefSeq Acc Id: XP_063143156   ⟸   XM_063287086
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q64591-F1-model_v2 AlphaFold Q64591 1-335 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693579
Promoter ID:EPDNEW_R4104
Type:multiple initiation site
Name:Decr1_1
Description:2,4-dienoyl-CoA reductase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0529,601,701 - 29,601,761EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70999 AgrOrtholog
BioCyc Gene G2FUF-41863 BioCyc
Ensembl Genes ENSRNOG00000008236 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00055000350 UniProtKB/Swiss-Prot
  ENSRNOG00060001119 UniProtKB/Swiss-Prot
  ENSRNOG00065015795 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000011330.7 UniProtKB/TrEMBL
  ENSRNOT00000097769.1 UniProtKB/TrEMBL
  ENSRNOT00000119084.1 UniProtKB/TrEMBL
  ENSRNOT00055000620 UniProtKB/Swiss-Prot
  ENSRNOT00060001551 UniProtKB/Swiss-Prot
  ENSRNOT00065026245 UniProtKB/Swiss-Prot
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6920489 IMAGE-MGC_LOAD
InterPro NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SDR_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:117543 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72723 IMAGE-MGC_LOAD
NCBI Gene 117543 ENTREZGENE
PANTHER 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING], MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SHORT-CHAIN DEHYDROGENASE/REDUCTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
  adh_short_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Decr1 PhenoGen
PRINTS GDHRDH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008236 RatGTEx
  ENSRNOG00055000350 RatGTEx
  ENSRNOG00060001119 RatGTEx
  ENSRNOG00065015795 RatGTEx
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AXK8_RAT UniProtKB/TrEMBL
  A0A8I6GDV3_RAT UniProtKB/TrEMBL
  A6IIA8 ENTREZGENE, UniProtKB/TrEMBL
  A6IIA9_RAT UniProtKB/TrEMBL
  DECR_RAT UniProtKB/Swiss-Prot
  G3V734 ENTREZGENE, UniProtKB/TrEMBL
  Q64591 ENTREZGENE
  Q6PCV4 ENTREZGENE
UniProt Secondary Q6PCV4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-12-15 Decr1  2,4-dienoyl-CoA reductase 1  Decr1  2,4-dienoyl CoA reductase 1, mitochondrial  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-07-09 Decr1  2,4-dienoyl CoA reductase 1, mitochondrial      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference