Hao2 (hydroxyacid oxidase 2) - Rat Genome Database

Name: Hao2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Hao2 (hydroxyacid oxidase 2) Rattus norvegicus

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Symbol:

Hao2

Name:

hydroxyacid oxidase 2

RGD ID:

70972

Description:

Enables (S)-2-hydroxy-acid oxidase activity; FMN binding activity; and identical protein binding activity. Involved in mandelate metabolic process. Located in peroxisome. Orthologous to human HAO2 (hydroxyacid oxidase 2); PARTICIPATES IN glyoxylate and dicarboxylate metabolic pathway; INTERACTS WITH 1-benzylpiperazine; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

(S)-2-hydroxy-acid oxidase, peroxisomal; 2-Hydroxyacid oxidase 2; Hao3; HAOX2; hydroxyacid oxidase (glycolate oxidase) 3; hydroxyacid oxidase 2 (long chain); hydroxyacid oxidase 3 (medium-chain); LCHAO; long chain alpha-hydroxy acid oxidase; long-chain L-2-hydroxy acid oxidase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HAO2 (hydroxyacid oxidase 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Hao2 (hydroxyacid oxidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Hao2 (hydroxyacid oxidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HAO2 (hydroxyacid oxidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	HAO2 (hydroxyacid oxidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Hao2 (hydroxyacid oxidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HAO2 (hydroxyacid oxidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	HAO2 (hydroxyacid oxidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Hao2 (hydroxyacid oxidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Hao2 (hydroxyacid oxidase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	HAO2 (hydroxyacid oxidase 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	hao2 (hydroxyacid oxidase 2 (long chain))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG18003	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	CYB2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F41E6.5	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	hao2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Candidate Gene For:

Bp73 Niddm62

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	188,888,848 - 188,921,567 (-)	NCBI		GRCr8
mRatBN7.2	2	186,200,137 - 186,232,997 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	186,200,504 - 186,224,425 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	193,857,178 - 193,881,103 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	191,652,271 - 191,676,187 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	186,489,732 - 186,513,657 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	200,785,492 - 200,808,868 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	200,778,122 - 200,808,857 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	220,246,117 - 220,278,112 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	193,532,833 - 193,557,229 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	193,495,586 - 193,519,983 (-)	NCBI
Celera	2	178,682,304 - 178,706,224 (-)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (ISO)

cholestasis (ISO)

Experimental Liver Cirrhosis (ISO)

Hajdu-Cheney syndrome (ISO)

hepatocellular carcinoma (ISO)

PHGDH deficiency (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

1-benzylpiperazine (EXP)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP,ISO)

2,2,2-tetramine (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-trinitrotoluene (EXP)

2-methoxyethanol (EXP)

3-chloropropane-1,2-diol (EXP)

4,4'-diaminodiphenylmethane (EXP,ISO)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

AB-Fubinaca (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amiodarone (EXP)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

benzbromarone (EXP)

benzo[a]pyrene (ISO)

bexarotene (EXP)

bisphenol A (EXP)

bromobenzene (EXP)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

clofibrate (EXP)

clofibric acid (EXP)

cobalt dichloride (ISO)

coumarin (EXP)

cyclosporin A (ISO)

dibromoacetic acid (EXP)

dibutyl phthalate (EXP)

dichloroacetic acid (ISO)

doxorubicin (ISO)

endosulfan (EXP,ISO)

epoxiconazole (ISO)

ethanol (EXP,ISO)

folic acid (ISO)

genistein (EXP,ISO)

graphene oxide (ISO)

hydrazine (ISO)

indole-3-methanol (EXP)

indometacin (EXP)

isotretinoin (ISO)

L-ethionine (EXP)

leflunomide (EXP)

methapyrilene (EXP,ISO)

mono(2-ethylhexyl) phthalate (ISO)

monosodium L-glutamate (EXP)

N-nitrosodiethylamine (EXP)

N-nitrosodimethylamine (EXP)

nefazodone (EXP)

nevirapine (EXP)

nickel atom (ISO)

O-methyleugenol (ISO)

omeprazole (EXP)

oxycodone (EXP)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP,ISO)

phenobarbital (EXP,ISO)

pirinixic acid (EXP,ISO)

pregnenolone 16alpha-carbonitrile (EXP,ISO)

profenofos (EXP)

propiconazole (EXP)

Propiverine (EXP)

quercetin (ISO)

resveratrol (EXP)

rotenone (EXP)

sodium arsenite (EXP,ISO)

sodium fluoride (ISO)

streptozocin (EXP)

tamoxifen (ISO)

testosterone (ISO)

thioacetamide (EXP)

triadimefon (EXP)

tributylstannane (EXP)

trichloroethene (EXP)

triphenyl phosphate (EXP)

trovafloxacin (EXP)

valdecoxib (EXP)

valproic acid (ISO)

vancomycin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

fatty acid alpha-oxidation (IBA)

fatty acid oxidation (IEA,ISO)

mandelate metabolic process (IDA)

Cellular Component

peroxisomal matrix (IBA,IEA,ISO)

peroxisome (IDA,IEA)

Molecular Function

(S)-2-hydroxy-acid oxidase activity (IBA,IDA,IEA,ISO)

FMN binding (IDA,IEA)

identical protein binding (IPI)

oxidoreductase activity (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

glyoxylate and dicarboxylate metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Molecular cloning and nucleotide sequence of cDNA encoding rat kidney long-chain L-2-hydroxy acid oxidase. Expression of the catalytically active recombinant protein as a chimaera.	Belmouden A, etal., Eur J Biochem 1993 May 15;214(1):17-25.
2.	Crystal structure analysis of recombinant rat kidney long chain hydroxy acid oxidase.	Cunane LM, etal., Biochemistry. 2005 Feb 8;44(5):1521-31.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	KEGG: Kyoto Encyclopedia of Genes and Genomes	KEGG
5.	Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease.	Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
6.	Use of a panel of congenic strains to evaluate differentially expressed genes as candidate genes for blood pressure quantitative trait loci.	Lee SJ, etal., Hypertens Res 2003 Jan;26(1):75-87.
7.	Gene Data Set	MGD Curation, June 12, 2002
8.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
9.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
10.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
11.	GOA pipeline	RGD automated data pipeline
12.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
14.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:1939137	PMID:3061453	PMID:10777549	PMID:15489334	PMID:18614015	PMID:20178365	PMID:23376485	PMID:26658681

Genomics

Comparative Map Data

Hao2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	188,888,848 - 188,921,567 (-)	NCBI		GRCr8
mRatBN7.2	2	186,200,137 - 186,232,997 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	186,200,504 - 186,224,425 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	193,857,178 - 193,881,103 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	191,652,271 - 191,676,187 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	186,489,732 - 186,513,657 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	200,785,492 - 200,808,868 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	200,778,122 - 200,808,857 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	220,246,117 - 220,278,112 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	193,532,833 - 193,557,229 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	193,495,586 - 193,519,983 (-)	NCBI
Celera	2	178,682,304 - 178,706,224 (-)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

HAO2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	119,368,785 - 119,394,130 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	119,368,779 - 119,394,130 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	119,911,408 - 119,936,753 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	119,712,925 - 119,738,274 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	119,623,443 - 119,648,793	NCBI
Celera	1	118,142,224 - 118,167,573 (+)	NCBI		Celera
Cytogenetic Map	1	p12	NCBI
HuRef	1	117,769,864 - 117,795,303 (+)	NCBI		HuRef
CHM1_1	1	120,026,956 - 120,052,305 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	119,375,119 - 119,407,329 (+)	NCBI		T2T-CHM13v2.0

Hao2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	98,781,835 - 98,802,692 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	98,781,837 - 98,800,555 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	98,874,519 - 98,895,376 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	98,874,521 - 98,893,239 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	98,678,442 - 98,697,153 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	99,003,638 - 99,022,274 (-)	NCBI		MGSCv36	mm8
Celera	3	100,210,261 - 100,228,985 (-)	NCBI		Celera
Cytogenetic Map	3	F2.2	NCBI
cM Map	3	42.9	NCBI

Hao2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955435	22,380,388 - 22,404,052 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955435	22,380,395 - 22,404,426 (+)	NCBI	ChiLan1.0	ChiLan1.0

HAO2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	111,985,096 - 112,010,469 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	111,588,950 - 111,614,331 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	83,160,326 - 83,185,688 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	118,157,570 - 118,182,957 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	118,157,037 - 118,182,957 (-)	Ensembl	panpan1.1		panPan2

HAO2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	56,505,463 - 56,529,441 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	56,505,506 - 56,528,954 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	56,154,387 - 56,178,251 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	57,378,470 - 57,402,319 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	57,378,390 - 57,401,965 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	56,414,332 - 56,438,197 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	56,446,707 - 56,470,576 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	57,036,690 - 57,060,535 (+)	NCBI		UU_Cfam_GSD_1.0

Hao2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	10,309,168 - 10,329,798 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936627	4,159,214 - 4,179,806 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936627	4,167,501 - 4,179,596 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HAO2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	101,588,861 - 101,732,304 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	101,588,510 - 101,787,818 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	111,579,140 - 111,777,885 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HAO2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	14,376,096 - 14,408,753 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	14,374,543 - 14,407,992 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	17,036,701 - 17,062,595 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hao2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624772	14,981,666 - 15,023,173 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624772	14,981,777 - 15,022,699 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Hao2
159 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	49
Count of miRNA genes:	48
Interacting mature miRNAs:	48
Transcripts:	ENSRNOT00000046942
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	114837527	211674221	Rat
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	161699179	222436696	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	168358098	223265385	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118463	226797303	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	81754530	227146641	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	18960362	228801039	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	136445150	202447032	Rat
152025245	Scl81	Serum cholesterol level QTL 81	3.49		blood cholesterol amount (VT:0000180)		2	122609194	206936711	Rat
70162	Bp63	Blood pressure QTL 63	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	114837675	212549332	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	78665619	219826953	Rat
10043136	Iddm54	Insulin dependent diabetes mellitus QTL 54	3.4	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	143657411	190602963	Rat
1302793	Bw16	Body weight QTL 16	5	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	2	157142209	202446871	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	43154682	202446871	Rat
61469	Bp16	Blood pressure QTL 16	5.64		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	2	169745596	214745596	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	135552573	202446871	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	157142078	211086598	Rat
4889834	Pur24	Proteinuria QTL 24	5.8	0.014	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	184114274	202447032	Rat
1359031	Bp275	Blood pressure QTL 275			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	185876309	219753474	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	56043031	202447032	Rat
1581502	Esta3	Estrogen-induced thymic atrophy QTL 3			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	136916935	189599348	Rat
9589044	Scfw1	Subcutaneous fat weight QTL 1	5.8	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	2	182171407	227171407	Rat
8694435	Bw166	Body weight QTL 166	14.08	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	2	182171407	227171407	Rat
1359032	Hrtrt18	Heart rate QTL 18			heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	2	157142078	192625452	Rat
2301966	Bp322	Blood pressure QTL 322	3.58		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150540301	202447032	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118275	202447032	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	81689826	221035911	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	42804607	202447032	Rat
8694194	Abfw1	Abdominal fat weight QTL 1	11.7	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	2	182171407	227171407	Rat
1359022	Ppulsi1	Prepulse inhibition QTL 1	3.63		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	2	136916935	213594495	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	249053267	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	78665619	249053267	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	76539322	202447032	Rat
2300189	Bmd48	Bone mineral density QTL 48	5.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	2	179335906	224335906	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	157142078	226277316	Rat
631501	Bp101	Blood pressure QTL 101	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150341684	202446871	Rat
2307174	Activ3	Activity QTL 3	4.83	0.000058	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	2	168594495	213594495	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	141194931	223265385	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	141596551	202447032	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	141194931	223265385	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	112456140	212696837	Rat
1598805	Memor8	Memory QTL 8	3		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	150341585	189039377	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	143157029	210020885	Rat
7488929	Bp366	Blood pressure QTL 366		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	184974550	193094998	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	133914684	202447032	Rat
738013	Alc15	Alcohol consumption QTL 15	4.1	0.00022	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	2	184165752	229165752	Rat
61401	Niddm2	Non-insulin dependent diabetes mellitus QTL 2	4.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	144599348	189599348	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	112456140	212696837	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	221167075	Rat
1354609	Niddm62	Non-insulin dependent diabetes mellitus QTL 62	4.72	0.000006	insulin secretion trait (VT:0003564)	plasma insulin level (CMO:0000342)	2	150540301	202447032	Rat
1598833	Bp295	Blood pressure QTL 295	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	147798556	192798556	Rat
61417	Cia10	Collagen induced arthritis QTL 10	3.4		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	2	179946951	224946951	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	81754530	222436696	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	46123260	202447032	Rat
8694383	Bw158	Body weight QTL 158	7.69	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	2	182171407	227171407	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	162765032	207765032	Rat
1598838	Bp290	Blood pressure QTL 290	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166539266	211539266	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	160564068	205564068	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	164073756	227146641	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	74786664	206665859	Rat
2293084	Iddm26	Insulin dependent diabetes mellitus QTL 26	2.9		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	174930955	213594495	Rat

Markers in Region

RH130402

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	186,200,443 - 186,200,659 (-)	MAPPER	mRatBN7.2
Rnor_6.0	2	200,808,346 - 200,808,561	NCBI	Rnor6.0
Rnor_5.0	2	220,277,948 - 220,278,163	UniSTS	Rnor5.0
RGSC_v3.4	2	193,532,773 - 193,532,988	UniSTS	RGSC3.4
Celera	2	178,682,244 - 178,682,459	UniSTS
RH 3.4 Map	2	1261.2	UniSTS
Cytogenetic Map	2	q34	UniSTS

RH130963

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	186,200,637 - 186,200,837 (-)	MAPPER	mRatBN7.2
Rnor_6.0	2	200,808,168 - 200,808,367	NCBI	Rnor6.0
Rnor_5.0	2	220,277,770 - 220,277,969	UniSTS	Rnor5.0
RGSC_v3.4	2	193,532,967 - 193,533,166	UniSTS	RGSC3.4
Celera	2	178,682,438 - 178,682,637	UniSTS
RH 3.4 Map	2	1259.0	UniSTS
Cytogenetic Map	2	q34	UniSTS

RH140192

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	186,200,301 - 186,200,497 (-)	MAPPER	mRatBN7.2
Rnor_6.0	2	200,808,508 - 200,808,703	NCBI	Rnor6.0
Rnor_5.0	2	220,278,110 - 220,278,305	UniSTS	Rnor5.0
RGSC_v3.4	2	193,532,631 - 193,532,826	UniSTS	RGSC3.4
Celera	2	178,682,102 - 178,682,297	UniSTS
RH 3.4 Map	2	1259.6	UniSTS
Cytogenetic Map	2	q34	UniSTS

AI232087

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	186,200,359 - 186,200,472 (-)	MAPPER	mRatBN7.2
Rnor_6.0	2	200,808,533 - 200,808,645	NCBI	Rnor6.0
Rnor_5.0	2	220,278,135 - 220,278,247	UniSTS	Rnor5.0
RGSC_v3.4	2	193,532,689 - 193,532,801	UniSTS	RGSC3.4
Celera	2	178,682,160 - 178,682,272	UniSTS
RH 3.4 Map	2	1261.2	UniSTS
Cytogenetic Map	2	q34	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
5	9	20	57	87	81	59	21	59	4	175	58	39	45	57	22

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_032082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103263	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063282643	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063282644	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC078781	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ210841	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB890678	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC948087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X67156	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000046942 ⟹ ENSRNOP00000040223

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	186,200,504 - 186,224,425 (-)	Ensembl
Rnor_6.0 Ensembl	2	200,785,507 - 200,808,501 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000091444 ⟹ ENSRNOP00000071695

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	186,200,504 - 186,216,343 (-)	Ensembl
Rnor_6.0 Ensembl	2	200,793,571 - 200,808,501 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000091845 ⟹ ENSRNOP00000074018

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	186,200,504 - 186,217,055 (-)	Ensembl
Rnor_6.0 Ensembl	2	200,778,122 - 200,808,857 (+)	Ensembl

RefSeq Acc Id:

NM_032082 ⟹ NP_114471

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	188,889,212 - 188,913,133 (-)	NCBI
mRatBN7.2	2	186,200,504 - 186,224,425 (-)	NCBI
Rnor_6.0	2	200,785,507 - 200,808,501 (+)	NCBI
Rnor_5.0	2	220,246,117 - 220,278,112 (+)	NCBI
RGSC_v3.4	2	193,532,833 - 193,557,229 (-)	RGD
Celera	2	178,682,304 - 178,706,224 (-)	RGD

Sequence:

show sequence

AGAGCTGGGCAATGAACCACTGTAGCGGGCTTTGCATTGCTGCCTCTACCTACAGCTATTACTG
GTCATTGGAAGACCTTAGAGTCAGAATCTTCTTGTGTAAGAGCCCTGAATGCTGTGACCAACCC
CAGTGTCTACAGCATCTTTGCAGCTGTTAATCTCACTGTTCTCGTTCCTATTGAAGAAATTACT
GGCCCAGAAATGCCTTTGGTGTGTTTGGCAGACTTTAAGGCACATGCGCAAAAGCAGCTGTCTA
AGACCTCCTGGGACTTTATTGAAGGAGAAGCTGACGACGGCATCACCTACAGTGAGAACATAGC
AGCATTTAAAAGAATCCGCCTCCGCCCCCGATACCTGAGAGATATGTCAAAGGTGGACACCAGG
ACCACAATCCAAGGGCAGGAGATCAGTGCTCCCATCTGCATCTCACCCACAGCCTTTCACTCCA
TTGCCTGGCCGGATGGAGAAAAGAGCACAGCTAGAGCTGCTCAGGAGGCCAACATCTGCTATGT
CATCAGCAGTTATGCCAGCTATTCCCTGGAAGATATTGTTGCTGCTGCCCCCGAAGGCTTTCGT
TGGTTCCAACTCTACATGAAGTCAGACTGGGACTTCAACAAGCAGATGGTTCAGAGGGCAGAAG
CCTTGGGTTTCAAAGCTTTGGTGATCACTATAGATACGCCTGTACTTGGCAATAGGCGACGGGA
CAAGAGAAACCAGCTGAATTTGGAGGCAAACATATTGTTGAAGGATCTCCGAGCCCTCAAAGAG
GAAAAGCCCACACAGTCTGTGCCCGTGTCTTTTCCGAAAGCATCTTTCTGCTGGAATGATCTTT
CCTTGCTTCAGAGTATAACTCGGTTGCCCATTATCCTCAAAGGGATTTTGACGAAAGAGGATGC
AGAGTTAGCAATGAAGCACAACGTCCAAGGCATCGTTGTTTCCAACCATGGTGGGAGGCAGCTT
GATGAGGTTTCTGCTTCAATTGATGCTCTGAGAGAAGTGGTGGCTGCTGTCAAAGGGAAAATTG
AAGTGTACATGGATGGTGGGGTTCGAACTGGCACTGATGTGTTGAAGGCACTGGCCCTTGGAGC
TAGGTGCATTTTTCTTGGGAGACCAATCCTTTGGGGCCTTGCCTGCAAGGGTGAAGATGGTGTT
AAGGAAGTTTTAGATATTCTAACAGCAGAACTCCATAGATGTATGACCCTTTCAGGCTGCCAGT
CAGTTGCTGAGATTAGTCCAGACCTGATTCAGTTCTCCAGATTATAAGGACCTACTGAGATCCC
TACAAGAGGAAGACAAGACTTCAACATAGTGTGTGAGCCTATTCTTCTTCGGTCCGATCATACC
TAGTAGTTTGAGCCCTCTACCTTGAGAAATCCAGATCGATGAAGAAAAGATAGCTAACAGCTAC
CAGAGGGGTGCATTTGGATGAAGGAATAACATCTAATGTTCTACAGGATAACTATAACTGACAA
TTAATTGACTATGTCCAATAGCCATGTTCCAGAAAGAAAGGAAATAGTTACATCTGGTGTGACA
TGCCAATTACTTTCATTTGATTATTATGTACACTATACATTATTAAAACGTCATACTGTGCCAT
AATTATGTGCAATTACTATGTATCAATTAAAACAACAATATATATTT

hide sequence

RefSeq Acc Id:

XM_006233022 ⟹ XP_006233084

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	188,888,848 - 188,913,196 (-)	NCBI
mRatBN7.2	2	186,200,137 - 186,224,481 (-)	NCBI
Rnor_6.0	2	200,785,492 - 200,808,868 (+)	NCBI
Rnor_5.0	2	220,246,117 - 220,278,112 (+)	NCBI

Sequence:

show sequence

AATATATTTTACCTCAGAGCTGGGCAATGAACCACTGTAGCGGGCTTTGCATTGCTGCCTCTAC
CTACAGCTATTACTGGTCATTGGAAGACCTTAGAGTCAGAATCTTCTTGTGTAAGAGCCCTGAA
TGCTGTGACCAACCCCAGTGTCTACAGCATCTTTGCAGCTGTTAATCTCACTGTTCTCGTTCCT
ATTGAAGAAATTACTGCCTTGAGCAATTCAGATATCTTAGAGATCCTGCGAACTCTCACTGATA
TCAGAGCAGACCTGACTTCACACAGTGGTACGAATGCCATCTCACAGTGAAAGGAAACCCATTG
AGACATGACACTGAGTAGGCGCTTAGGAGGCCCAGAAATGCCTTTGGTGTGTTTGGCAGACTTT
AAGGCACATGCGCAAAAGCAGCTGTCTAAGACCTCCTGGGACTTTATTGAAGGAGAAGCTGACG
ACGGCATCACCTACAGTGAGAACATAGCAGCATTTAAAAGAATCCGCCTCCGCCCCCGATACCT
GAGAGATATGTCAAAGGTGGACACCAGGACCACAATCCAAGGGCAGGAGATCAGTGCTCCCATC
TGCATCTCACCCACAGCCTTTCACTCCATTGCCTGGCCGGATGGAGAAAAGAGCACAGCTAGAG
CTGCTCAGGAGGCCAACATCTGCTATGTCATCAGCAGTTATGCCAGCTATTCCCTGGAAGATAT
TGTTGCTGCTGCCCCCGAAGGCTTTCGTTGGTTCCAACTCTACATGAAGTCAGACTGGGACTTC
AACAAGCAGATGGTTCAGAGGGCAGAAGCCTTGGGTTTCAAAGCTTTGGTGATCACTATAGATA
CGCCTGTACTTGGCAATAGGCGACGGGACAAGAGAAACCAGCTGAATTTGGAGGCAAACATATT
GTTGAAGGATCTCCGAGCCCTCAAAGAGGTGAGAAAGGAAAAGCCCACACAGTCTGTCCCCGTG
TCTTTTCCGAAAGCATCTTTCTGCTGGAATGATCTTTCCTTGCTTCAGAGTATAACTCGGTTGC
CCATTATCCTCAAAGGGATTTTGACGAAAGAGGATGCAGAGTTAGCAATGAAGCACAACGTCCA
AGGCATCGTTGTTTCCAACCATGGTGGGAGGCAGCTTGATGAGGTTTCTGCTTCAATTGATGCT
CTGAGAGAAGTGGTGGCTGCTGTCAAAGGGAAAATTGAAGTGTACATGGATGGTGGGGTTCGAA
CTGGCACTGATGTGTTGAAGGCACTGGCCCTTGGAGCTAGGTGCATTTTTCTTGGGAGACCAAT
CCTTTGGGGCCTTGCCTGCAAGGGTGAAGATGGTGTTAAGGAAGTTTTAGATATTCTAACAGCA
GAACTCCATAGATGTATGACCCTTTCAGGCTGCCAGTCAGTTGCTGAGATTAGTCCAGACCTGA
TTCAGTTCTCCAGATTATAAGGACCTACTGAGATCCCTACAAGAGGAAGACAAGACTTCAACAT
AGTGTGTGAGCCTATTCTTCTTCGGTCCGATCATACCTAGTAGTTTGAGCCCTCTACCTTGAGA
AATCCAGATGGATGAAGAAAAGATAGCTAACAGCTACCAGAGGGGTGCATTTGGATGAAGGAAT
AACATCTAATGTTCTACAGGATAACTATAACTGACAATTAATTGACTATGTCCAATAGCCATGT
TCCAGAAAGAAAGGAAATAGTTACATCTGGTGTGACATGCCAATTACCTTCATTTGATTATTAT
GTACACTATACATTATTGAAACGTCATACTGTGCCATAATTATGTGCAATTACTATGTATCAAT
TAAAACAACAATATATATTTAAAAATGAAGACAGCATTATCCTGATGTTTTACTCATTCCCTCC
TGCAAGAAATATTTGGAATTTAATAAACTTTAATCCATGAAGTCATAATGTAGCAGAGAGCAAA
TGAATGTGTGAATTATGCAAGGTTCTGACACAGCATGTTACTGAAGTGTTATGATCTATTGCCT
AATGTCCATTATTGACAGTAGCTGACCTCAAAAAAAAAGAGGAAGATTTTGAAACTCATTTTCC
AGGATACATGACTAAATTAACTATTCCAGCCACTTACTGATATATGAAAAAGAAGATATCTTTA
TTCTGGTCATAATCATTTTGTCAAATAAATCTAGACCTTTTCAATAAAGTGTATAGAGTGAAAA
TAA

hide sequence

RefSeq Acc Id:

XM_006233024 ⟹ XP_006233086

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	188,888,848 - 188,913,196 (-)	NCBI
mRatBN7.2	2	186,200,137 - 186,224,481 (-)	NCBI
Rnor_6.0	2	200,785,492 - 200,808,868 (+)	NCBI
Rnor_5.0	2	220,246,117 - 220,278,112 (+)	NCBI

Sequence:

show sequence

AATATATTTTACCTCAGAGCTGGGCAATGAACCACTGTAGCGGGCTTTGCATTGCTGCCTCTAC
CTACAGCTATTACTGGTCATTGGAAGACCTTAGAGTCAGAATCTTCTTGTGTAAGAGCCCTGAA
TGCTGTGACCAACCCCAGTGTCTACAGCATCTTTGCAGCTGTTAATCTCACTGTTCTCGTTCCT
ATTGAAGAAATTACTGCCTTGAGCAATTCAGATATCTTAGAGATCCTGCGAACTCTCACTGATA
TCAGAGCAGACCTGACTTCACACAGTGGTACGAATGCCATCTCACAGTGAAAGGAAACCCATTG
AGACATGACACTGAGTAGGCGCTTAGGAGGCCCAGAAATGCCTTTGGTGTGTTTGGCAGACTTT
AAGGCACATGCGCAAAAGCAGCTGTCTAAGACCTCCTGGGACTTTATTGAAGGAGAAGCTGACG
ACGGCATCACCTACAGTGAGAACATAGCAGCATTTAAAAGAATCCGCCTCCGCCCCCGATACCT
GAGAGATATGTCAAAGGTGGACACCAGGACCACAATCCAAGGGCAGGAGATCAGTGCTCCCATC
TGCATCTCACCCACAGCCTTTCACTCCATTGCCTGGCCGGATGGAGAAAAGAGCACAGCTAGAG
CTGCTCAGGAGGCCAACATCTGCTATGTCATCAGCAGTTATGCCAGCTATTCCCTGGAAGATAT
TGTTGCTGCTGCCCCCGAAGGCTTTCGTTGGTTCCAACTCTACATGAAGTCAGACTGGGACTTC
AACAAGCAGATGGTTCAGAGGGCAGAAGCCTTGGGTTTCAAAGCTTTGGTGATCACTATAGATA
CGCCTGTACTTGGCAATAGGCGACGGGACAAGAGAAACCAGCTGAATTTGGAGGCAAACATATT
GTTGAAGGATCTCCGAGCCCTCAAAGAGGAAAAGCCCACACAGTCTGTCCCCGTGTCTTTTCCG
AAAGCATCTTTCTGCTGGAATGATCTTTCCTTGCTTCAGAGTATAACTCGGTTGCCCATTATCC
TCAAAGGGATTTTGACGAAAGAGGATGCAGAGTTAGCAATGAAGCACAACGTCCAAGGCATCGT
TGTTTCCAACCATGGTGGGAGGCAGCTTGATGAGGTTTCTGCTTCAATTGATGCTCTGAGAGAA
GTGGTGGCTGCTGTCAAAGGGAAAATTGAAGTGTACATGGATGGTGGGGTTCGAACTGGCACTG
ATGTGTTGAAGGCACTGGCCCTTGGAGCTAGGTGCATTTTTCTTGGGAGACCAATCCTTTGGGG
CCTTGCCTGCAAGGGTGAAGATGGTGTTAAGGAAGTTTTAGATATTCTAACAGCAGAACTCCAT
AGATGTATGACCCTTTCAGGCTGCCAGTCAGTTGCTGAGATTAGTCCAGACCTGATTCAGTTCT
CCAGATTATAAGGACCTACTGAGATCCCTACAAGAGGAAGACAAGACTTCAACATAGTGTGTGA
GCCTATTCTTCTTCGGTCCGATCATACCTAGTAGTTTGAGCCCTCTACCTTGAGAAATCCAGAT
GGATGAAGAAAAGATAGCTAACAGCTACCAGAGGGGTGCATTTGGATGAAGGAATAACATCTAA
TGTTCTACAGGATAACTATAACTGACAATTAATTGACTATGTCCAATAGCCATGTTCCAGAAAG
AAAGGAAATAGTTACATCTGGTGTGACATGCCAATTACCTTCATTTGATTATTATGTACACTAT
ACATTATTGAAACGTCATACTGTGCCATAATTATGTGCAATTACTATGTATCAATTAAAACAAC
AATATATATTTAAAAATGAAGACAGCATTATCCTGATGTTTTACTCATTCCCTCCTGCAAGAAA
TATTTGGAATTTAATAAACTTTAATCCATGAAGTCATAATGTAGCAGAGAGCAAATGAATGTGT
GAATTATGCAAGGTTCTGACACAGCATGTTACTGAAGTGTTATGATCTATTGCCTAATGTCCAT
TATTGACAGTAGCTGACCTCAAAAAAAAAGAGGAAGATTTTGAAACTCATTTTCCAGGATACAT
GACTAAATTAACTATTCCAGCCACTTACTGATATATGAAAAAGAAGATATCTTTATTCTGGTCA
TAATCATTTTGTCAAATAAATCTAGACCTTTTCAATAAAGTGTATAGAGTGAAAATAA

hide sequence

RefSeq Acc Id:

XM_006233025 ⟹ XP_006233087

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	188,888,848 - 188,913,196 (-)	NCBI
mRatBN7.2	2	186,200,137 - 186,224,481 (-)	NCBI
Rnor_6.0	2	200,785,492 - 200,808,868 (+)	NCBI
Rnor_5.0	2	220,246,117 - 220,278,112 (+)	NCBI

Sequence:

show sequence

AATATATTTTACCTCAGAGCTGGGCAATGAACCACTGTAGCGGGCTTTGCATTGCTGCCTCTAC
CTACAGCTATTACTGGTCATTGGAAGACCTTAGAGTCAGAATCTTCTTGTGTAAGAGCCCTGAA
TGCTGTGACCAACCCCAGTGTCTACAGCATCTTTGCAGCTGTTAATCTCACTGTTCTCGTTCCT
ATTGAAGAAATTACTGGCCCAGAAATGCCTTTGGTGTGTTTGGCAGACTTTAAGGCACATGCGC
AAAAGCAGCTGTCTAAGACCTCCTGGGACTTTATTGAAGGAGAAGCTGACGACGGCATCACCTA
CAGTGAGAACATAGCAGCATTTAAAAGAATCCGCCTCCGCCCCCGATACCTGAGAGATATGTCA
AAGGTGGACACCAGGACCACAATCCAAGGGCAGGAGATCAGTGCTCCCATCTGCATCTCACCCA
CAGCCTTTCACTCCATTGCCTGGCCGGATGGAGAAAAGAGCACAGCTAGAGCTGCTCAGGAGGC
CAACATCTGCTATGTCATCAGCAGTTATGCCAGCTATTCCCTGGAAGATATTGTTGCTGCTGCC
CCCGAAGGCTTTCGTTGGTTCCAACTCTACATGAAGTCAGACTGGGACTTCAACAAGCAGATGG
TTCAGAGGGCAGAAGCCTTGGGTTTCAAAGCTTTGGTGATCACTATAGATACGCCTGTACTTGG
CAATAGGCGACGGGACAAGAGAAACCAGCTGAATTTGGAGGCAAACATATTGTTGAAGGATCTC
CGAGCCCTCAAAGAGGTGAGAAAGGAAAAGCCCACACAGTCTGTCCCCGTGTCTTTTCCGAAAG
CATCTTTCTGCTGGAATGATCTTTCCTTGCTTCAGAGTATAACTCGGTTGCCCATTATCCTCAA
AGGGATTTTGACGAAAGAGGATGCAGAGTTAGCAATGAAGCACAACGTCCAAGGCATCGTTGTT
TCCAACCATGGTGGGAGGCAGCTTGATGAGGTTTCTGCTTCAATTGATGCTCTGAGAGAAGTGG
TGGCTGCTGTCAAAGGGAAAATTGAAGTGTACATGGATGGTGGGGTTCGAACTGGCACTGATGT
GTTGAAGGCACTGGCCCTTGGAGCTAGGTGCATTTTTCTTGGGAGACCAATCCTTTGGGGCCTT
GCCTGCAAGGGTGAAGATGGTGTTAAGGAAGTTTTAGATATTCTAACAGCAGAACTCCATAGAT
GTATGACCCTTTCAGGCTGCCAGTCAGTTGCTGAGATTAGTCCAGACCTGATTCAGTTCTCCAG
ATTATAAGGACCTACTGAGATCCCTACAAGAGGAAGACAAGACTTCAACATAGTGTGTGAGCCT
ATTCTTCTTCGGTCCGATCATACCTAGTAGTTTGAGCCCTCTACCTTGAGAAATCCAGATGGAT
GAAGAAAAGATAGCTAACAGCTACCAGAGGGGTGCATTTGGATGAAGGAATAACATCTAATGTT
CTACAGGATAACTATAACTGACAATTAATTGACTATGTCCAATAGCCATGTTCCAGAAAGAAAG
GAAATAGTTACATCTGGTGTGACATGCCAATTACCTTCATTTGATTATTATGTACACTATACAT
TATTGAAACGTCATACTGTGCCATAATTATGTGCAATTACTATGTATCAATTAAAACAACAATA
TATATTTAAAAATGAAGACAGCATTATCCTGATGTTTTACTCATTCCCTCCTGCAAGAAATATT
TGGAATTTAATAAACTTTAATCCATGAAGTCATAATGTAGCAGAGAGCAAATGAATGTGTGAAT
TATGCAAGGTTCTGACACAGCATGTTACTGAAGTGTTATGATCTATTGCCTAATGTCCATTATT
GACAGTAGCTGACCTCAAAAAAAAAGAGGAAGATTTTGAAACTCATTTTCCAGGATACATGACT
AAATTAACTATTCCAGCCACTTACTGATATATGAAAAAGAAGATATCTTTATTCTGGTCATAAT
CATTTTGTCAAATAAATCTAGACCTTTTCAATAAAGTGTATAGAGTGAAAATAA

hide sequence

RefSeq Acc Id:

XM_039103263 ⟹ XP_038959191

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	188,888,848 - 188,921,553 (-)	NCBI
mRatBN7.2	2	186,200,137 - 186,232,997 (-)	NCBI

RefSeq Acc Id:

XM_063282643 ⟹ XP_063138713

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	188,888,848 - 188,913,196 (-)	NCBI

RefSeq Acc Id:

XM_063282644 ⟹ XP_063138714

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	188,888,848 - 188,921,567 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_114471	(Get FASTA)	NCBI Sequence Viewer
	XP_006233084	(Get FASTA)	NCBI Sequence Viewer
	XP_006233086	(Get FASTA)	NCBI Sequence Viewer
	XP_006233087	(Get FASTA)	NCBI Sequence Viewer
	XP_038959191	(Get FASTA)	NCBI Sequence Viewer
	XP_063138713	(Get FASTA)	NCBI Sequence Viewer
	XP_063138714	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH78781	(Get FASTA)	NCBI Sequence Viewer
	CAA47629	(Get FASTA)	NCBI Sequence Viewer
	CBF69476	(Get FASTA)	NCBI Sequence Viewer
	CBU94284	(Get FASTA)	NCBI Sequence Viewer
	EDL85557	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000040223.1
	ENSRNOP00000071695.2
	ENSRNOP00000074018.2
	ENSRNOP00055046857
	ENSRNOP00060018855
	ENSRNOP00065044078
GenBank Protein	Q07523	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_114471 ⟸ NM_032082

- UniProtKB:

Q07523 (UniProtKB/Swiss-Prot), A6K3E3 (UniProtKB/TrEMBL), A0A0G2K713 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRTTI
QGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPEGFRWFQ
LYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLKDLRALKEEKP
TQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQGIVVSNHGGRQLDEV
SASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGVKEV
LDILTAELHRCMTLSGCQSVAEISPDLIQFSRL

hide sequence

RefSeq Acc Id:	XP_006233084 ⟸ XM_006233022
- Peptide Label:	isoform X2
- UniProtKB:	A0A8L2UQG3 (UniProtKB/TrEMBL), A0A0G2K713 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTLSRRLGGPEMPLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLR DMSKVDTRTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIV AAAPEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILL KDLRALKEVRKEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQG IVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPIL WGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQFSRL hide sequence

RefSeq Acc Id:	XP_006233086 ⟸ XM_006233024
- Peptide Label:	isoform X3
- UniProtKB:	A0A0G2K713 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTLSRRLGGPEMPLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLR DMSKVDTRTTIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIV AAAPEGFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILL KDLRALKEEKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQGIVV SNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGL ACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQFSRL hide sequence

RefSeq Acc Id:	XP_006233087 ⟸ XM_006233025
- Peptide Label:	isoform X4
- UniProtKB:	A0A0G2K713 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPLVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRTTI QGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPEGFRWFQ LYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEANILLKDLRALKEVRK EKPTQSVPVSFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAMKHNVQGIVVSNHGGRQL DEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGARCIFLGRPILWGLACKGEDGV KEVLDILTAELHRCMTLSGCQSVAEISPDLIQFSRL hide sequence

Ensembl Acc Id:

ENSRNOP00000071695 ⟸ ENSRNOT00000091444

Ensembl Acc Id:

ENSRNOP00000040223 ⟸ ENSRNOT00000046942

Ensembl Acc Id:

ENSRNOP00000074018 ⟸ ENSRNOT00000091845

RefSeq Acc Id:	XP_038959191 ⟸ XM_039103263
- Peptide Label:	isoform X4
- UniProtKB:	A0A0G2K713 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063138714 ⟸ XM_063282644
- Peptide Label:	isoform X5
- UniProtKB:	Q07523 (UniProtKB/Swiss-Prot), A6K3E3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063138713 ⟸ XM_063282643
- Peptide Label:	isoform X1

Protein Domains

FMN hydroxy acid dehydrogenase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q07523-F1-model_v2	AlphaFold	Q07523	1-353	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691603

Promoter ID:

EPDNEW_R2128

Type:

multiple initiation site

Name:

Hao2_1

Description:

hydroxyacid oxidase 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	200,785,525 - 200,785,585	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:70972	AgrOrtholog
BioCyc Gene	G2FUF-51904	BioCyc
Ensembl Genes	ENSRNOG00000019470	Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055032816	UniProtKB/Swiss-Prot
	ENSRNOG00060013867	UniProtKB/Swiss-Prot
	ENSRNOG00065031098	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000046942.3	UniProtKB/Swiss-Prot
	ENSRNOT00000091444.2	UniProtKB/TrEMBL
	ENSRNOT00000091845.2	UniProtKB/TrEMBL
	ENSRNOT00055056753	UniProtKB/Swiss-Prot
	ENSRNOT00060023703	UniProtKB/Swiss-Prot
	ENSRNOT00065053630	UniProtKB/Swiss-Prot
Gene3D-CATH	3.20.20.70	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7132928	IMAGE-MGC_LOAD
InterPro	Aldolase_TIM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Alpha-hydoxy_acid_DH_FMN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	FMN-dep_DH	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	FMN_HAD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	FMN_hydac_DH_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:84029	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:93324	IMAGE-MGC_LOAD
NCBI Gene	84029	ENTREZGENE
PANTHER	HYDROXYACID OXIDASE 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	S -2-HYDROXY-ACID OXIDASE-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	FMN_dh	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Hao2	PhenoGen
PIRSF	Al-hdrx_acd_dh	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	FMN_HYDROXY_ACID_DH_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	FMN_HYDROXY_ACID_DH_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000019470	RatGTEx
	ENSRNOG00055032816	RatGTEx
	ENSRNOG00060013867	RatGTEx
	ENSRNOG00065031098	RatGTEx
Superfamily-SCOP	FMN-linked oxidoreductases	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2K713	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2UQG3	ENTREZGENE, UniProtKB/TrEMBL
	A6K3E3	ENTREZGENE, UniProtKB/TrEMBL
	HAOX2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-29	Hao2	hydroxyacid oxidase 2	Hao2	hydroxyacid oxidase 2 (long chain)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Hao2	hydroxyacid oxidase 2 (long chain)	Hao3	hydroxyacid oxidase (glycolate oxidase) 3	Symbol and Name updated	1299863	APPROVED
2002-07-09	Hao3	hydroxyacid oxidase (glycolate oxidase) 3			Symbol and Name updated to reflect Human and Mouse nomenclature	70877	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_disease	high expression associated with lower blood pressure in a SS/Jr.WKY congenic strain, compared to the SS/Jr	631320
gene_expression	expressed in kidney	631320
gene_function	oxidizes L-2 hydroxy acids into keto acids; FMN-dependent	631320
gene_protein	1648-bp cDNA codes for 352 aa protein	70759

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)