Spon2 (spondin 2) - Rat Genome Database

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Gene: Spon2 (spondin 2) Rattus norvegicus
Analyze
Symbol: Spon2
Name: spondin 2
RGD ID: 708584
Description: Enables signaling receptor binding activity. Involved in cell adhesion; cellular response to platelet-derived growth factor stimulus; and vascular associated smooth muscle cell proliferation. Predicted to be located in extracellular space. Predicted to be active in extracellular matrix. Orthologous to human SPON2 (spondin 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: F-spondin; LOC100361829; LOC100910790; LOC171569; mindin; mindin precursor; spondin 2, extracellular matrix protein; spondin-2; spondin-2-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Spon2em1Holi
Genetic Models: SD-Spon2em1Holi
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81481,713,070 - 81,742,510 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1481,731,188 - 81,742,609 (+)EnsemblGRCr8
mRatBN7.21477,505,695 - 77,518,001 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1477,511,901 - 77,517,996 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1481,954,278 - 81,960,081 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01483,194,828 - 83,200,631 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01479,640,141 - 79,645,944 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01482,815,158 - 82,824,529 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1482,818,663 - 82,824,599 (+)Ensemblrn6Rnor6.0
Rnor_5.01483,501,025 - 83,510,376 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera1476,428,066 - 76,433,860 (+)NCBICelera
RGSC_v3.11482,975,275 - 82,978,160 (-)NCBI
Cytogenetic Map14q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(2,4,5-trichlorophenoxy)acetic acid  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chloroethene  (ISO)
chloroprene  (EXP,ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP)
clofibrate  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
disodium selenite  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethyl methanesulfonate  (ISO)
fulvestrant  (ISO)
furan  (ISO)
graphene oxide  (ISO)
ketoconazole  (EXP)
leflunomide  (EXP)
lipopolysaccharide  (ISO)
methotrexate  (ISO)
mitoxantrone  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monosodium L-glutamate  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-ethyl-N-nitrosourea  (ISO)
naphthalene  (ISO)
nickel atom  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentanal  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
propanal  (ISO)
Ptaquiloside  (ISO)
quercetin  (ISO)
quinolin-8-ol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
tamoxifen  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
topotecan  (EXP)
tributylstannane  (EXP)
trichloroethene  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
extracellular matrix  (IBA,IEA,ISO)
extracellular space  (IEA,ISO)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. F-spondin and mindin: two structurally and functionally related genes expressed in the hippocampus that promote outgrowth of embryonic hippocampal neurons. Feinstein Y, etal., Development 1999 Aug;126(16):3637-48.
2. Microarray gene expression profiling in meningiomas: differential expression according to grade or histopathological subtype. Fèvre-Montange M, etal., Int J Oncol. 2009 Dec;35(6):1395-407. doi: 10.3892/ijo_00000457.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8. Mindin regulates vascular smooth muscle cell phenotype and prevents neointima formation. Zhu LH, etal., Clin Sci (Lond). 2015 Jul;129(2):129-45. doi: 10.1042/CS20140679.
Additional References at PubMed
PMID:14691481   PMID:15489334   PMID:16300627   PMID:16736493   PMID:18780763   PMID:19056867   PMID:19903741   PMID:22592270   PMID:23533145   PMID:24006456  


Genomics

Comparative Map Data
Spon2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81481,713,070 - 81,742,510 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1481,731,188 - 81,742,609 (+)EnsemblGRCr8
mRatBN7.21477,505,695 - 77,518,001 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1477,511,901 - 77,517,996 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1481,954,278 - 81,960,081 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01483,194,828 - 83,200,631 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01479,640,141 - 79,645,944 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01482,815,158 - 82,824,529 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1482,818,663 - 82,824,599 (+)Ensemblrn6Rnor6.0
Rnor_5.01483,501,025 - 83,510,376 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera1476,428,066 - 76,433,860 (+)NCBICelera
RGSC_v3.11482,975,275 - 82,978,160 (-)NCBI
Cytogenetic Map14q21NCBI
SPON2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3841,166,932 - 1,208,844 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl41,166,932 - 1,208,962 (-)Ensemblhg38GRCh38
GRCh3741,160,720 - 1,202,632 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3641,150,723 - 1,156,597 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3441,150,552 - 1,156,427NCBI
Celera41,093,221 - 1,099,481 (-)NCBICelera
Cytogenetic Map4p16.3NCBI
HuRef41,129,322 - 1,171,336 (-)NCBIHuRef
CHM1_141,160,505 - 1,202,404 (-)NCBICHM1_1
T2T-CHM13v2.041,165,604 - 1,208,039 (-)NCBIT2T-CHM13v2.0
Spon2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39533,370,862 - 33,375,596 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl533,355,528 - 33,375,799 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38533,213,518 - 33,218,254 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl533,198,184 - 33,218,455 (-)Ensemblmm10GRCm38
MGSCv37533,556,167 - 33,560,887 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36533,530,375 - 33,535,040 (-)NCBIMGSCv36mm8
Celera530,692,605 - 30,697,322 (-)NCBICelera
Cytogenetic Map5B1NCBI
cM Map517.5NCBI
Spon2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955514596,829 - 604,051 (-)Ensembl
ChiLan1.0NW_004955514598,840 - 603,390 (-)NCBIChiLan1.0ChiLan1.0
SPON2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v231,497,529 - 1,521,340 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan141,458,112 - 1,469,560 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v041,309,473 - 1,351,529 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.141,195,307 - 1,201,168 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl41,195,848 - 1,200,400 (-)EnsemblpanPan2panpan1.1
SPON2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1391,411,245 - 91,421,245 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha393,879,686 - 93,886,426 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0392,411,007 - 92,417,759 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl392,411,007 - 92,417,965 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1391,584,382 - 91,591,120 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0391,637,257 - 91,643,961 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0392,021,312 - 92,028,059 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Spon2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528568,385,733 - 68,391,985 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647722,087,394 - 22,093,723 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647722,087,450 - 22,093,677 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPON2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8447,180 - 450,538 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.18447,176 - 450,829 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SPON2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12747,609,170 - 47,615,507 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2747,609,922 - 47,615,496 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660513,986,077 - 3,992,451 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spon2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475526,045,493 - 26,053,476 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475526,045,617 - 26,049,951 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Spon2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11171,621,320 - 71,627,976 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Spon2
244 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:409
Count of miRNA genes:235
Interacting mature miRNAs:273
Transcripts:ENSRNOT00000008262
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143802371083023710Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143900944484009444Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143802371083023710Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143802371083023710Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143802371083023710Rat

Markers in Region
AI504350  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21477,517,626 - 77,517,726 (+)MAPPERmRatBN7.2
Rnor_6.01482,824,155 - 82,824,254NCBIRnor6.0
Rnor_5.01483,510,002 - 83,510,101UniSTSRnor5.0
Celera1476,433,486 - 76,433,585UniSTS
Cytogenetic Map14q21UniSTS


Genetic Models
This gene Spon2 is modified in the following models/strains:
SD-Spon2em1Holi    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 12 61 127 57 60 41 83 41 293 165 11 118 69 72 19 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000008262   ⟹   ENSRNOP00000008262
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1481,731,188 - 81,742,609 (+)Ensembl
mRatBN7.2 Ensembl1477,511,901 - 77,517,996 (+)Ensembl
Rnor_6.0 Ensembl1482,818,663 - 82,824,599 (+)Ensembl
RefSeq Acc Id: NM_138533   ⟹   NP_612542
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81481,736,716 - 81,742,510 (+)NCBI
mRatBN7.21477,512,207 - 77,518,001 (+)NCBI
Rnor_6.01482,818,735 - 82,824,529 (+)NCBI
Rnor_5.01483,501,025 - 83,510,376 (+)NCBI
Celera1476,428,066 - 76,433,860 (+)RGD
Sequence:
RefSeq Acc Id: XM_017599062   ⟹   XP_017454551
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81481,713,070 - 81,742,505 (+)NCBI
mRatBN7.21477,505,695 - 77,518,001 (+)NCBI
Rnor_6.01482,815,158 - 82,824,529 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599063   ⟹   XP_017454552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81481,713,070 - 81,742,505 (+)NCBI
mRatBN7.21477,510,734 - 77,518,001 (+)NCBI
Rnor_6.01482,817,235 - 82,824,529 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_612542 (Get FASTA)   NCBI Sequence Viewer  
  XP_017454551 (Get FASTA)   NCBI Sequence Viewer  
  XP_017454552 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH78734 (Get FASTA)   NCBI Sequence Viewer  
  EDM00132 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000008262
  ENSRNOP00000008262.5
GenBank Protein Q9WV75 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_612542   ⟸   NM_138533
- Peptide Label: precursor
- UniProtKB: Q9WV75 (UniProtKB/Swiss-Prot),   A6IK68 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454551   ⟸   XM_017599062
- Peptide Label: isoform X1
- UniProtKB: Q9WV75 (UniProtKB/Swiss-Prot),   A6IK68 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454552   ⟸   XM_017599063
- Peptide Label: isoform X1
- UniProtKB: Q9WV75 (UniProtKB/Swiss-Prot),   A6IK68 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000008262   ⟸   ENSRNOT00000008262
Protein Domains
Spondin   TSP type-1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WV75-F1-model_v2 AlphaFold Q9WV75 1-330 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708584 AgrOrtholog
BioCyc Gene G2FUF-15253 BioCyc
Ensembl Genes ENSRNOG00000006033 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000008262 ENTREZGENE
  ENSRNOT00000008262.7 UniProtKB/Swiss-Prot
Gene3D-CATH 2.20.100.10 UniProtKB/Swiss-Prot
  2.60.40.2130 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7121065 IMAGE-MGC_LOAD
InterPro Spondin/Thrombospondin_T1 UniProtKB/Swiss-Prot
  Spondin_N UniProtKB/Swiss-Prot
  Spondin_N_sf UniProtKB/Swiss-Prot
  TSP1_rpt UniProtKB/Swiss-Prot
  TSP1_rpt_sf UniProtKB/Swiss-Prot
  TSP1_spondin_dom UniProtKB/Swiss-Prot
KEGG Report rno:171569 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93184 IMAGE-MGC_LOAD
NCBI Gene 171569 ENTREZGENE
PANTHER SPONDIN UniProtKB/Swiss-Prot
  SPONDIN-2 UniProtKB/Swiss-Prot
Pfam Spond_N UniProtKB/Swiss-Prot
  TSP1_spondin UniProtKB/Swiss-Prot
PhenoGen Spon2 PhenoGen
PROSITE SPONDIN UniProtKB/Swiss-Prot
  TSP1 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000006033 RatGTEx
SMART TSP1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF82895 UniProtKB/Swiss-Prot
UniProt A6IK68 ENTREZGENE, UniProtKB/TrEMBL
  Q9WV75 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Spon2  spondin 2  LOC100910790  spondin-2-like  Data merged from RGD:6496621 737654 PROVISIONAL
2016-01-21 Spon2  spondin 2  Spon2  spondin 2, extracellular matrix protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-04-17 Spon2  spondin 2, extracellular matrix protein  LOC100361829  spondin-2-like  Data merged from RGD:2319347 737654 PROVISIONAL
2012-07-05 LOC100910790  spondin-2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-05-05 LOC100361829  spondin-2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-07-08 Spon2  spondin 2, extracellular matrix protein  LOC171569  F-spondin  Symbol and Name updated 1299863 APPROVED