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Gene: Lzts1 (leucine zipper tumor suppressor 1) Rattus norvegicus

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Symbol:

Lzts1

Name:

leucine zipper tumor suppressor 1

RGD ID:

708565

Description:

Involved in regulation of dendrite morphogenesis and regulation of synaptic plasticity. Located in several cellular components, including apical plasma membrane; dendrite; and postsynaptic membrane. Is active in glutamatergic synapse and postsynaptic density membrane. Human ortholog(s) of this gene implicated in breast carcinoma; esophageal cancer; esophagus squamous cell carcinoma; and squamous cell carcinoma. Orthologous to human LZTS1 (leucine zipper tumor suppressor 1); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

leucine zipper putative tumor suppressor 1; leucine zipper, putative tumor suppressor 1; PSD-Zip70; Psdzip70; similar to leucine zipper putative tumor suppressor 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LZTS1 (leucine zipper tumor suppressor 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Lzts1 (leucine zipper, putative tumor suppressor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Lzts1 (leucine zipper tumor suppressor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LZTS1 (leucine zipper tumor suppressor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LZTS1 (leucine zipper tumor suppressor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Lzts1 (leucine zipper tumor suppressor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LZTS1 (leucine zipper tumor suppressor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LZTS1 (leucine zipper tumor suppressor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Lzts1 (leucine zipper tumor suppressor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Lzts1 (leucine zipper tumor suppressor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PAQR3 (progestin and adipoQ receptor family member 3)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	LZTS1 (leucine zipper tumor suppressor 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Lzts1 (leucine zipper, putative tumor suppressor 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	lzts1 (leucine zipper, putative tumor suppressor 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	lzts1 (leucine zipper, putative tumor suppressor 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG15365	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG15365	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	F35B3.7	Alliance	DIOPT (Ensembl Compara\|OrthoFinder)
Xenopus tropicalis (tropical clawed frog):	lzts1	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	lzts1	Alliance	DIOPT (OMA\|OrthoFinder\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	25,309,502 - 25,364,942 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	25,309,507 - 25,364,940 (+)	Ensembl				GRCr8
mRatBN7.2	16	20,542,756 - 20,598,204 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	20,542,809 - 20,598,203 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	23,910,466 - 23,965,921 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	27,341,958 - 27,397,438 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	23,275,771 - 23,331,223 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	22,250,452 - 22,306,667 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	22,250,470 - 22,306,662 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	22,147,127 - 22,202,136 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	22,243,137 - 22,300,978 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	20,519,932 - 20,575,243 (+)	NCBI		Celera
RGSC_v3.1	16	22,243,134 - 22,300,975 (+)	NCBI
Cytogenetic Map	16	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

breast carcinoma (ISO)

esophageal cancer (ISO)

Esophageal Neoplasms (ISO)

esophagus squamous cell carcinoma (ISO)

Prostatic Neoplasms (ISO)

squamous cell carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1-naphthyl isothiocyanate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

3,4-methylenedioxymethamphetamine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

Ampullosporin (EXP)

antirheumatic drug (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

cadmium dichloride (EXP)

calcitriol (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

Cuprizon (EXP)

dorsomorphin (ISO)

entinostat (ISO)

fenamidone (ISO)

flavonoids (EXP)

fluvastatin (ISO)

FR900359 (ISO)

furan (EXP)

gentamycin (EXP)

iron dichloride (ISO)

ivermectin (ISO)

ketamine (EXP)

Lasiocarpine (ISO)

malathion (ISO)

maneb (ISO)

mercury dibromide (ISO)

Mesaconitine (EXP)

methylmercury chloride (ISO)

Moniliformin (ISO)

Monobutylphthalate (EXP)

nocodazole (ISO)

okadaic acid (ISO)

panobinostat (ISO)

paracetamol (EXP)

paraquat (ISO)

pentanal (ISO)

phenylmercury acetate (ISO)

propanal (ISO)

SB 431542 (ISO)

sinapic acid (ISO)

Soman (EXP)

sotorasib (ISO)

sunitinib (ISO)

temozolomide (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trametinib (ISO)

trichostatin A (ISO)

troglitazone (ISO)

tunicamycin (ISO)

valproic acid (ISO)

vorinostat (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of macroautophagy (ISO)

regulation of dendrite morphogenesis (IBA,IMP)

regulation of postsynapse assembly (IEA,ISO)

regulation of synaptic plasticity (IBA,IMP,NAS)

Cellular Component

apical plasma membrane (IDA)

cell body (IDA)

cytoplasm (IEA)

dendritic shaft (IDA)

dendritic spine (IBA,IDA,IEA)

glutamatergic synapse (IDA,IEA,IEP,ISO)

plasma membrane (IEA)

postsynaptic density (IEA)

postsynaptic density membrane (IDA,IEP)

postsynaptic membrane (IDA)

synapse (IEA)

Molecular Function

protein binding (IPI,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Characterization of densin-180, a new brain-specific synaptic protein of the O-sialoglycoprotein family.	Apperson ML, etal., J Neurosci 1996 Nov 1;16(21):6839-52.
2.	Down-regulation of tumor suppressor gene FEZ1/LZTS1 in breast carcinoma involves promoter methylation and associates with metastasis.	Chen L, etal., Breast Cancer Res Treat. 2009 Aug;116(3):471-8. doi: 10.1007/s10549-008-0147-6. Epub 2008 Aug 7.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors.	Ishii H, etal., Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3928-33.
6.	The postsynaptic density and dendritic raft localization of PSD-Zip70, which contains an N-myristoylation sequence and leucine-zipper motifs.	Konno D, etal., J Cell Sci 2002 Dec 1;115(Pt 23):4695-706.
7.	Collaboration of PSD-Zip70 with its binding partner, SPAR, in dendritic spine maturity.	Maruoka H, etal., J Neurosci. 2005 Feb 9;25(6):1421-30.
8.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
9.	GOA pipeline	RGD automated data pipeline
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:22354037

Genomics

Comparative Map Data

Lzts1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	25,309,502 - 25,364,942 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	16	25,309,507 - 25,364,940 (+)	Ensembl				GRCr8
mRatBN7.2	16	20,542,756 - 20,598,204 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	20,542,809 - 20,598,203 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	16	23,910,466 - 23,965,921 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	27,341,958 - 27,397,438 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	23,275,771 - 23,331,223 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	22,250,452 - 22,306,667 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	22,250,470 - 22,306,662 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	16	22,147,127 - 22,202,136 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	16	22,243,137 - 22,300,978 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	16	20,519,932 - 20,575,243 (+)	NCBI		Celera
RGSC_v3.1	16	22,243,134 - 22,300,975 (+)	NCBI
Cytogenetic Map	16	p14	NCBI

LZTS1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	20,246,165 - 20,303,963 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	20,246,165 - 20,303,963 (-)	Ensembl			hg38	GRCh38
GRCh37	8	20,103,676 - 20,161,474 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	20,147,956 - 20,157,083 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	8	20,147,956 - 20,157,083	NCBI
Celera	8	19,066,273 - 19,075,376 (-)	NCBI		Celera
Cytogenetic Map	8	p21.3	NCBI
HuRef	8	18,643,682 - 18,652,790 (-)	NCBI		HuRef
CHM1_1	8	20,305,442 - 20,314,568 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	20,511,247 - 20,569,040 (-)	NCBI		T2T-CHM13v2.0

Lzts1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	69,585,311 - 69,636,901 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	69,585,321 - 69,636,877 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	8	69,132,659 - 69,184,249 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	69,132,669 - 69,184,225 (-)	Ensembl			mm10	GRCm38
MGSCv37	8	71,659,402 - 71,664,852 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	8	72,064,492 - 72,069,942 (-)	NCBI		MGSCv36	mm8
Celera	8	71,685,839 - 71,691,289 (-)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI
cM Map	8	33.88	NCBI

Lzts1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	43,909,681 - 43,962,971 (-)	Ensembl
ChiLan1.0	NW_004955403	43,909,722 - 43,962,965 (-)	NCBI	ChiLan1.0	ChiLan1.0

LZTS1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	38,727,693 - 38,785,761 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	14,453,283 - 14,511,350 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	19,471,361 - 19,529,437 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	16,418,501 - 16,476,111 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	16,418,496 - 16,476,111 (-)	Ensembl			panPan2	panpan1.1

LZTS1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	36,764,235 - 36,814,204 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	36,744,061 - 36,811,972 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	37,357,148 - 37,408,722 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	36,989,870 - 37,041,266 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	36,989,853 - 37,042,926 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	36,925,719 - 36,977,061 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	36,773,887 - 36,825,207 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	36,942,939 - 36,994,282 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Lzts1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	14,185,606 - 14,239,234 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936555	4,330,787 - 4,384,932 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936555	4,330,878 - 4,384,883 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LZTS1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	4,346,480 - 4,404,168 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	4,344,496 - 4,404,208 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	4,633,021 - 4,693,042 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LZTS1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	18,315,243 - 18,377,492 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	18,315,130 - 18,324,345 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666052	23,878,741 - 23,937,808 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lzts1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	15,956,236 - 16,006,192 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624758	15,956,300 - 16,006,174 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Lzts1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	13	20,258,014 - 20,312,970 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Lzts1
330 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	396
Count of miRNA genes:	215
Interacting mature miRNAs:	285
Transcripts:	ENSRNOT00000015799
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1549842	Bp248	Blood pressure QTL 248		0.01	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	16	387123	45387123	Rat
2307172	Activ4	Activity QTL 4	3.71	0.00023	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	1	33425095	Rat
1354584	Despr6	Despair related QTL 6	3.1	0.0067	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	1	39568015	Rat
737819	Hcas4	Hepatocarcinoma susceptibility QTL 4	4.43		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	16	4234212	53708481	Rat
631517	Scl9	Serum cholesterol level QTL 9	3.3		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	16	15748006	25801629	Rat
1354625	Despr7	Despair related QTL 7	3.16	0.016	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	4744222	49744222	Rat
61405	Niddm6	Non-insulin dependent diabetes mellitus QTL 6	3.66	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	16	1	26734272	Rat
631830	Alc7	Alcohol consumption QTL 7	2.9		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	1	26734272	Rat
7411664	Foco30	Food consumption QTL 30	11	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	4354822	49354822	Rat
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	longest distance run on treadmill (CMO:0001406)	16	387123	45387123	Rat
70183	BpQTLcluster13	Blood pressure QTL cluster 13	3.654		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	16	4234212	49757901	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4234212	66955197	Rat
1600369	Hcas8	Hepatocarcinoma susceptibility QTL 8			liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	16	16278184	27244292	Rat
2303566	Bw90	Body weight QTL 90	2		body mass (VT:0001259)	body weight (CMO:0000012)	16	1	39568015	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	839086	66195506	Rat
2306902	Bp339	Blood pressure QTL 339		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	3386790	49757901	Rat
1300133	Rf24	Renal function QTL 24	3.64		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	16	3386790	26128267	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	839086	66195506	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	839086	66195506	Rat
634355	Rends4	Renal damage susceptibility QTL 4		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	16	1	26734272	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17730818	72536785	Rat
2293343	Glom16	Glomerulus QTL 16	7.4		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	16	839086	52786090	Rat
2301406	Kidm39	Kidney mass QTL 39		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	16	15905802	60905802	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	839086	66195506	Rat
6903319	Bw114	Body weight QTL 114	2.7	0.0037	body mass (VT:0001259)	body weight (CMO:0000012)	16	3301683	48301683	Rat

Markers in Region

D16Rat47

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	16	25,358,329 - 25,358,559 (+)	Marker Load Pipeline
mRatBN7.2	16	20,591,591 - 20,591,821 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	22,299,348 - 22,299,577	NCBI	Rnor6.0
Rnor_5.0	16	22,195,975 - 22,196,204	UniSTS	Rnor5.0
RGSC_v3.4	16	22,293,370 - 22,293,600	RGD	RGSC3.4
RGSC_v3.4	16	22,293,371 - 22,293,600	UniSTS	RGSC3.4
Celera	16	20,568,683 - 20,568,912	UniSTS
RGSC_v3.1	16	22,293,368 - 22,293,598	RGD
SHRSP x BN Map	16	7.88	RGD
SHRSP x BN Map	16	7.88	UniSTS
FHH x ACI Map	16	12.1799	RGD
Cytogenetic Map	16	p14	UniSTS

D16Rat77

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	16	25,335,081 - 25,335,256 (+)	Marker Load Pipeline
mRatBN7.2	16	20,568,335 - 20,568,727 (+)	MAPPER	mRatBN7.2
mRatBN7.2	16	20,568,335 - 20,568,510 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	22,276,339 - 22,276,761	NCBI	Rnor6.0
Rnor_6.0	16	22,276,339 - 22,276,513	NCBI	Rnor6.0
Rnor_5.0	16	22,172,966 - 22,173,388	UniSTS	Rnor5.0
Rnor_5.0	16	22,172,966 - 22,173,140	UniSTS	Rnor5.0
RGSC_v3.4	16	22,270,123 - 22,270,297	UniSTS	RGSC3.4
RGSC_v3.4	16	22,270,122 - 22,270,297	RGD	RGSC3.4
Celera	16	20,545,421 - 20,545,595	UniSTS
RGSC_v3.1	16	22,270,120 - 22,270,295	RGD
RH 2.0 Map	16	289.2	RGD
SHRSP x BN Map	16	7.88	RGD
Cytogenetic Map	16	p14	UniSTS

RH129739

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	20,597,966 - 20,598,146 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	22,306,430 - 22,306,609	NCBI	Rnor6.0
Rnor_5.0	16	22,201,899 - 22,202,078	UniSTS	Rnor5.0
RGSC_v3.4	16	22,300,741 - 22,300,920	UniSTS	RGSC3.4
Celera	16	20,575,006 - 20,575,185	UniSTS
Cytogenetic Map	16	p14	UniSTS

AU049658

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_5.0	4	227,443,857 - 227,444,176	NCBI	Rnor5.0
Rnor_5.0	16	22,173,039 - 22,173,212	NCBI	Rnor5.0
RGSC_v3.4	16	22,270,197 - 22,270,370	UniSTS	RGSC3.4
RGSC_v3.4	4	165,944,416 - 165,944,734	UniSTS	RGSC3.4
Celera	16	20,545,495 - 20,545,667	UniSTS
Celera	4	150,880,136 - 150,880,454	UniSTS
Cytogenetic Map	16	p14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	66	163	91	90	59	83	59	6	339	182	11	139	74	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_153470	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039094242	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB075607	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474134	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000015799 ⟹ ENSRNOP00000015800

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	25,309,507 - 25,364,940 (+)	Ensembl
mRatBN7.2 Ensembl	16	20,542,809 - 20,598,203 (+)	Ensembl
Rnor_6.0 Ensembl	16	22,250,470 - 22,306,662 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000128629 ⟹ ENSRNOP00000104992

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	16	25,309,507 - 25,364,940 (+)	Ensembl

RefSeq Acc Id:

NM_153470 ⟹ NP_703200

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	25,309,553 - 25,364,942 (+)	NCBI
mRatBN7.2	16	20,542,809 - 20,598,204 (+)	NCBI
Rnor_6.0	16	22,250,500 - 22,306,667 (+)	NCBI
Rnor_5.0	16	22,147,127 - 22,202,136 (+)	NCBI
RGSC_v3.4	16	22,243,137 - 22,300,978 (+)	RGD
Celera	16	20,519,932 - 20,575,243 (+)	RGD

Sequence:

show sequence

GCCAGCTGGCGGGCTCTGGGCGGCTGCGACAAGCTCAGAGTCCGAAAGTTTCTCTGCCTTTCTG
CTGCTCCTGGGAGTGTGACTTGAGCGACGCGGGATCAGTCGGCTCCAGTGGCTCTCTAGAAAAA
GAGAAAGGGGTACTACACAAAACACACCGAAAAATCAAAATCTGCAGCCATTTGCAGCTATCTC
CGAGGGGGAGGAGGGCAGACAGGTCCATGGCTCTCTCGGGCTCTGAGAAGCTTTTGCTCTGACC
ACAGTCCCCTCGGCTGAGCCAGGACTACATTTCGCTGCTGTCTCCAGGCCCCTCTTGTGCCCTG
CAGGCCCTTGGTTCCTCGTCACCATGGGCAGTGTGAGCAGCCTTATCTCAGGCCACAGTCTCCA
CAGCAAGCACTGTCGTGCTTCCCAGTACAAACTGCGCAAATCCTCCCACCTCAAGAAGCTCAAC
CGGTACTCAGATGGGCTTCTGAGGTTTGGCTTCTCCCAGGACTCGGGCCGTGGCAAGTCCAGCT
CCAAAATGGGGAAAAGCGAAGACTTCTTCTACATCAAAGTCAGCCAGAAGGCCCGAGGCTCCCA
TCGCCCAGACTACACAGCACTGTCCAGTGGGGACATGGGGGGCCAGACTGGAGTAGATTTTGAT
CCAGCCACTCCACCAAAGCTCATGCCCTTCTCCAGTCAACTGGAAATGAGTTCAGACAAGGCGG
CGGTGAGGCCCACTGCCTTCAAGCCTGTGTTGCCACGGTCAGGAGCCATTCTCCACTCTTCACC
TGAGAGTACCAACCACCAGCTTCATCCCATGCCTCCAGATAAGCCCAAGGAACAGGAGCTGAAG
CCAGGCCTGTGCTCAGGGGCACTGTCTGACTCGGGCCGGAACTCCATGTCTAGCCTGCCCACGC
ATAGCACCACCAGCAGCTACCAGCTGGATCCTCTGGTCACCCCCGTGGGGCCTACTAGCCGTTT
TGGGGGTTCAGCTCACAACATCACACAAGGCATCATCCTTCAGGACAGTAATATGATGAGCCTG
AAGGCTCTGTCATTCTCTGATGGGGGCAGCAAGCTGGCTCACCCAGGCAAGGTAGAAAAGGGCT
CCTCCTGTGTGCGTTCCCCACTCTCCACGGATGAGTGCACCATTCAGGAGCTGGAGCAGAAGCT
GCTGCAGCGGGAGACTGCACTACAGAAGCTACAGCGCAGTTTCGATGAGAAGGAGTTTGCCTCT
GGCCAGACCTTCGAGGAGCGGCCACGGCGGACTAGAGACGAACTGGAGTGCCTGGAACCTAAGA
GCAAGCTGAAGCCAGCCTCCCAGAAGAGCCAGCGCACCCAGCAGGTACTCCAGCTGCAGGTGTT
ACAGTTGCAGCAGGAGAAACGGCAGCTGAGGCAGGAGCTAGAGAGCCTAATGAAGGAGCAGGAC
CTGCTGGAGACCAAGCTGAGGTCCTACGAGCGGGAGAAAACCAACTTCGCCCCTGCACTGGAGG
AGACCCAATGGGAGGTGTGCCAGAAGTCAGGTGAGATCTCTCTTCTGAAGCAACAGCTCAAAGA
ATCCCAAATGGAGGTGAATGCTAAGGCCAGTGAGATCCTTAGCCTGAAGGCACAGCTGAAGGAC
ACCCGGGGCAAGCTTGAGGGAATGGAGTTGAAGACACAGGACTTGGAGAGCGCCTTGCGCACCA
AGGGGCTAGAGCTGGAGGTCTGTGAGAATGAACTGCAGCGCAAGAAGAATGAGGCAGAGCTGCT
GAGAGAGAAGGTGAACCTTTTAGAACAGGAGCTGCTGGAGCTGCGGGCCCAGGCGGCCCTGCAT
CGAGATGCAGCACCCCTGGGCCCTCCAGGGATTGGGCTGACTTTCTCAGAGGACATCCCTGCTC
TGCAGCGGGAGCTGGATCGGCTGCGGGCTGAGCTGAAGGAGGAGAGGCAAGGCCATGACCAGAT
GTCCTCGGGATTCCAGCATGAGCGGTTGGTGTGGAAGGAAGAGAAGGAGAAAGTGATCCAGTAC
CAAAAGCAGCTGCAACAGAGCTACTTGGCCATGTACCAGCGCAACCAGCGTCTAGAGAAGGCCC
TGCAGCAGCTGGCCCGTGGGGATATTGCAGGGGAGCCCTTTGAAATTGACCTGGAGGGAGCTGA
CATTCCCTATGAGGATATCATAGCCACTGAGATCTGAGGGGCTACCTCGGGGATGGAGGGCTGG
GGACTAGACCCCAGAAAGCAGGGAGGACTGAGCCTGTCCCAAGAGCCCCTCTGAGAGAAGCCAC
CTCTGGGATCCAGATTCAGGAGTCCCCAGTGGTGGGTAGGGGTTACCACATAGCCTTTCCTCCC
CTCCTGCCTTTCTCAGCCTAACTAACCCTGCTGCTTATAAGACCTTGATCTGCGAACCCCAAGC
TCTCCTAGAGGTATGCTCAGGGAGCTTTATGTGCTGGTTGAGGTTTCTCTTGACTTTGGTCTCA
TTCAAAGTAGTGAGAAAGACACCCCATCAGGAAAGGGGGCAACTGCCATACAGGCCAAATGGCA
CCCAAGGACAGAAACATTTTCCCTGTTGTCCCTAAACCCCCACCATCCCCTGGGCATCTTGGGA
TGCCTTTGGGAATAGAAAGAAGCCATGTGTAACCAGAAGCCTTGGACCTCGTCTTCACTACAGC
CTGTTCTGCTCTGACTGTGGTGGTGGAGGGGTTGTGTCGCCACGTAGTTGAGCCAGCAAGTCAT
GGGAGGAAGGGGTAGATGGACAGTCCGCCATTACGGAACCTTTGCAGGTCTCAAGAGGTCCGGT
GGGAGTTGAAAGGAGAGAACCAAGGCAGATGGGGAGTGGAGTCTAAAATGAGCTGCATAGCCCC
TTTGACCTCAGTGGTCACTCTGTTTAAAGCCATAGACATTGGGGGTCCCAGGTGGGGTACAGGG
AACTGACATGAGACATAGATTCTCAGCTGTGCCAGGGGATCCTCCTCAGCCTCCAATATTGAAT
GTTTTTTCTTTCCAGAACACTAGACGCTGGCTCAGATCCAAAATAGCCCATCCACTTAGATAGT
GTGCATGGGAGCTGGACATTAGCCTCCCTTGTCTGTGGCCCAAGTCAGCAGCTTCTCTTTCCCT
TATAGCATTGTCAGTGTGCTGATAGGCTGCCGTCCAGGCAGGAGAGATACAGGGTGCATAAAAA
GAGCCTTATAAATATCCCAAACCACCCACTTTCCTCCCKCCGTGTGGCAGCACCCCAGGCTGTA
AGAATTCAGTCTAGAAAGCAGCATGTGAGCTTGTGGGAGCCTGGCCTTGTCTTTTGAAGATAGC
CAGATCTAGGGGCAGAGGGAAGTGCAGTTGCTGGGTTGAAGGAATTATCTTCTCTCTCCTTCCC
ACTTCCATTCTGTGTTTTCCAAAGCAAGCCAGATCAAGCAGGCAGCCAAGCTGCTCCATATTCT
ATTTTTGGCCCTTACCACAGCTGTTGTTGGTAGGACACCCAGCCCTTGCTGGATTCCTGAGCCA
TGTGTTTGCCTGGTGGGCGGGACCCAGGATATTGGAGATGTAAGGGAGGGTCTGTGTGCTTGGT
AGTCCAGGAACCAACCTGAGTTCTACCTCCCTAATGCTGGTCCTTAAGGTGGATCCCAGCCCTA
GTGACCTTGTCTTCCCGTGGGCTTTCTTCCCTTCCTTGTATCTGCAGGCTAGGTGCCTCCCCTG
TACGTGGTACTACTTTCTGTCCCTGCGGTTAGATTGGCCCTCTCCTACTACTGACTTTCAACAG
CACACTATTCTCTGGTCTACCACTGCCCAGAGTCACATGCTCACTTAAATCTGGAATCTACAGG
CCAAAGACGACTCCCCCAACTTGCACGGTCGTACACTCCACTGAACACAGGTCACAGCCCAGTT
TAAAGAGTCCATAGCCCTCAGTTCTCAGTTGTGTACCAGTCTGTGCCTTGTCTGAGTCCTTCCC
ATTGAGACTGTCCAACAGACAGAAAGAAAGATGGGGGTTTCCTGCCTCTCTCTAGATTGAAGGA
CTCCTTCCTCTGAGAGAAGTCCAGAAGTCCAGTGCTATGCTATGGAGTCCTTGCCCAGAAGCAG
ACACTAGGCCTGGGCAGACCTGTGCTCTCTCTGTGCAGGGTGCCTTCTGTTCACAGGGGTTCTG
CCCAGTAGTCCTGCCGAGGTCATCGTTGAGACCTCTGCCTGGGGACTGCTTACCCTTTAAGATG
GCAGATGCCTTCCCAAGACTGCTGTCAGCCTGAGGTCCCAAGGTAGCTCCAAGACGCAACTGTG
CTGTAACCTAATAACCTTGCCTTCGTGTGGGCTTTCTTTCCTCTCCTGTCCTAAAGCATCCTCA
CTGTTTGTGGCCCATGCCCATGTTGGACGGCTAGATGGAACAGTGACTGAACAGGGCCTCAGGT
GTGCAGGTTCAGGGCAGACAAGTAGTCTGCCACACCTCGTCTCTCAGCTCCACACTGCTTTCCA
GAGGTGTCTGGTTCCAGACTGTGGCTGCTCTCTGAAGGAAGAACGGCAGCTAGCATCACCTCAA
GGAAGGGCCTTGTAGTGTCAGACTCCCACGGGGTACCTCCTTGCTCGATTTTTTCCTCTCTCGG
CACACTTGAACTTTAGCATGATAACGTTTTCAGGGGATCGGCATCACTCCTCTGAGAGACACTT
GCTGATCCTCTCGTCGCTGGCTCCAGCTTGGGCTGTGTCTCAGGTAAGACASATGTCCAAGGGA
AAGCCAGGCTGGACCAGAGATTTCCCTAGGACCTGAGTTCTCCTCAGACGCCATAGAACAGGCC
ACAGTGCCCCTCAGTGGAGACTGCTTTCCCTCTTGAACACTGGAGCCCTCAGTAGAGGCTGGCT
TCGGATGGACTGGCATTTGGAAGACCAAGTACATAGTTATTTTTCTCTTCCCTGTTTCTGGTTT
GCTTTGCTCTTGATGGCTTCGTTTTGTTTTATTTTTGAAGTTCTTTGTTGGCTCCGTAAACTAT
TTCTGCTACTTTTATGTTTTTATTTATGAATAAAGAATGCCATTTCTCATGTCTTCACAGTCAA
AAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039094242 ⟹ XP_038950170

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	25,309,502 - 25,364,942 (+)	NCBI
mRatBN7.2	16	20,542,756 - 20,598,204 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_703200	(Get FASTA)	NCBI Sequence Viewer
	XP_038950170	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAC16535	(Get FASTA)	NCBI Sequence Viewer
	EDL84665	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000015800
	ENSRNOP00000015800.2
GenBank Protein	Q8CFC9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_703200 ⟸ NM_153470

- UniProtKB:

Q8CFC9 (UniProtKB/Swiss-Prot), A6KU68 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGSVSSLISGHSLHSKHCRASQYKLRKSSHLKKLNRYSDGLLRFGFSQDSGRGKSSSKMGKSED
FFYIKVSQKARGSHRPDYTALSSGDMGGQTGVDFDPATPPKLMPFSSQLEMSSDKAAVRPTAFK
PVLPRSGAILHSSPESTNHQLHPMPPDKPKEQELKPGLCSGALSDSGRNSMSSLPTHSTTSSYQ
LDPLVTPVGPTSRFGGSAHNITQGIILQDSNMMSLKALSFSDGGSKLAHPGKVEKGSSCVRSPL
STDECTIQELEQKLLQRETALQKLQRSFDEKEFASGQTFEERPRRTRDELECLEPKSKLKPASQ
KSQRTQQVLQLQVLQLQQEKRQLRQELESLMKEQDLLETKLRSYEREKTNFAPALEETQWEVCQ
KSGEISLLKQQLKESQMEVNAKASEILSLKAQLKDTRGKLEGMELKTQDLESALRTKGLELEVC
ENELQRKKNEAELLREKVNLLEQELLELRAQAALHRDAAPLGPPGIGLTFSEDIPALQRELDRL
RAELKEERQGHDQMSSGFQHERLVWKEEKEKVIQYQKQLQQSYLAMYQRNQRLEKALQQLARGD
IAGEPFEIDLEGADIPYEDIIATEI

hide sequence

Ensembl Acc Id:

ENSRNOP00000015800 ⟸ ENSRNOT00000015799

RefSeq Acc Id:	XP_038950170 ⟸ XM_039094242
- Peptide Label:	isoform X1
- UniProtKB:	Q8CFC9 (UniProtKB/Swiss-Prot), A6KU68 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000104992 ⟸ ENSRNOT00000128629

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8CFC9-F1-model_v2	AlphaFold	Q8CFC9	1-601	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700055

Promoter ID:

EPDNEW_R10579

Type:

initiation region

Name:

Lzts1_1

Description:

leucine zipper tumor suppressor 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	22,250,477 - 22,250,537	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:708565	AgrOrtholog
BioCyc Gene	G2FUF-11708	BioCyc
Ensembl Genes	ENSRNOG00000011826	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000015799	ENTREZGENE
	ENSRNOT00000015799.5	UniProtKB/Swiss-Prot
InterPro	LZTS	UniProtKB/Swiss-Prot
KEGG Report	rno:266711	UniProtKB/Swiss-Prot
NCBI Gene	266711	ENTREZGENE
PANTHER	PTHR19354	UniProtKB/Swiss-Prot
	PTHR19354:SF5	UniProtKB/Swiss-Prot
Pfam	Fez1	UniProtKB/Swiss-Prot
PhenoGen	Lzts1	PhenoGen
RatGTEx	ENSRNOG00000011826	RatGTEx
UniProt	A0ABK0LU29_RAT	UniProtKB/TrEMBL
	A6KU68	ENTREZGENE, UniProtKB/TrEMBL
	LZTS1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-07-27	Lzts1	leucine zipper tumor suppressor 1	Lzts1	leucine zipper, putative tumor suppressor 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Lzts1	leucine zipper, putative tumor suppressor 1	Psdzip70	PSD-Zip70	Symbol and Name updated	1299863	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	localized to dendritic spines of the postsynaptic density and postsynaptic membrane	1299532

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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