Dhrs4 (dehydrogenase/reductase 4) - Rat Genome Database

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Gene: Dhrs4 (dehydrogenase/reductase 4) Rattus norvegicus
Analyze
Symbol: Dhrs4
Name: dehydrogenase/reductase 4
RGD ID: 708482
Description: Predicted to enable several functions, including 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity; alcohol dehydrogenase (NADP+) activity; and retinal dehydrogenase (NAD+) activity. Predicted to be involved in several processes, including positive regulation of reactive oxygen species metabolic process; retinal metabolic process; and steroid metabolic process. Located in peroxisome. Orthologous to several human genes including DHRS4 (dehydrogenase/reductase 4); PARTICIPATES IN retinol metabolic pathway; vitamin A deficiency pathway; INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: carbonyl reductase; CR; DCR-AKL; dehydrogenase/reductase (SDR family) member 4; dehydrogenase/reductase SDR family member 4; LOC266686; NADP-retinol dehydrogenase; NADPH-dependent carbonyl reductase; NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase; NADPH-dependent retinol dehydrogenase/reductase; NDRD; peroxisomal short-chain alcohol dehydrogenase; PHCR; PSCD; short chain dehydrogenase/reductase family 25C member 2
RGD Orthologs
Human
Mouse
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,924,482 - 32,948,103 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1532,936,522 - 32,948,101 (+)EnsemblGRCr8
mRatBN7.21528,966,544 - 28,978,135 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,966,553 - 28,978,127 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1530,812,271 - 30,823,840 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,959,479 - 31,971,048 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01530,201,827 - 30,213,396 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01534,155,043 - 34,167,073 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,155,504 - 34,167,072 (+)Ensemblrn6Rnor6.0
Rnor_5.01538,045,908 - 38,057,499 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41533,609,570 - 33,621,142 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1528,542,580 - 28,554,149 (+)NCBICelera
RGSC_v3.11533,625,453 - 33,636,460 (+)NCBI
Cytogenetic Map15p13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinal  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzbromarone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
ciguatoxin CTX1B  (ISO)
clofibrate  (EXP,ISO)
clofibric acid  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
diuron  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP)
finasteride  (EXP)
flutamide  (EXP)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
indometacin  (EXP)
inulin  (ISO)
L-ethionine  (EXP)
methapyrilene  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
Muraglitazar  (EXP)
N-nitrosomorpholine  (EXP)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
okadaic acid  (ISO)
omeprazole  (EXP)
ozone  (ISO)
p-toluidine  (EXP)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phlorizin  (ISO)
pirinixic acid  (EXP,ISO)
resveratrol  (ISO)
selenium atom  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sunitinib  (ISO)
Tesaglitazar  (EXP)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
trichloroethene  (EXP,ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
mitochondrion  (IEA,ISO,ISS)
nucleus  (ISO)
peroxisomal membrane  (ISO)
peroxisome  (IBA,IDA,IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Identification of peroxisomal proteins by using M13 phage protein VI phage display: molecular evidence that mammalian peroxisomes contain a 2,4-dienoyl-CoA reductase. Fransen M, etal., Biochem J 1999 Jun 1;340 ( Pt 2):561-8.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:12680773   PMID:14651853   PMID:17230527   PMID:18334214   PMID:18571493   PMID:19056333   PMID:19442656   PMID:20178365   PMID:21525035   PMID:22227495   PMID:23036705   PMID:23376485  
PMID:25931508  


Genomics

Comparative Map Data
Dhrs4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,924,482 - 32,948,103 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1532,936,522 - 32,948,101 (+)EnsemblGRCr8
mRatBN7.21528,966,544 - 28,978,135 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,966,553 - 28,978,127 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1530,812,271 - 30,823,840 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,959,479 - 31,971,048 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01530,201,827 - 30,213,396 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01534,155,043 - 34,167,073 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,155,504 - 34,167,072 (+)Ensemblrn6Rnor6.0
Rnor_5.01538,045,908 - 38,057,499 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41533,609,570 - 33,621,142 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1528,542,580 - 28,554,149 (+)NCBICelera
RGSC_v3.11533,625,453 - 33,636,460 (+)NCBI
Cytogenetic Map15p13NCBI
DHRS4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381423,953,770 - 23,969,279 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1423,953,713 - 23,969,279 (+)Ensemblhg38GRCh38
GRCh371424,422,979 - 24,438,488 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,492,805 - 23,508,328 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341423,492,804 - 23,508,326NCBI
Celera144,285,601 - 4,303,126 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef144,539,991 - 4,555,519 (+)NCBIHuRef
CHM1_11424,421,623 - 24,437,128 (+)NCBICHM1_1
T2T-CHM13v2.01418,154,102 - 18,169,615 (+)NCBIT2T-CHM13v2.0
Dhrs4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,715,880 - 55,727,797 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,716,215 - 55,727,797 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381455,478,741 - 55,490,340 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,478,758 - 55,490,340 (+)Ensemblmm10GRCm38
MGSCv371456,097,595 - 56,109,177 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361454,432,868 - 54,444,411 (+)NCBIMGSCv36mm8
Celera1453,283,670 - 53,295,252 (+)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
DHRS4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21525,352,031 - 25,367,508 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,568,524 - 24,584,000 (+)NCBINHGRI_mPanPan1
PanPan1.11422,831,557 - 22,953,699 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1422,831,756 - 22,846,695 (+)EnsemblpanPan2panpan1.1
DHRS4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,046,532 - 4,058,498 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl84,046,544 - 4,084,744 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha83,968,424 - 3,980,384 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.084,157,197 - 4,169,172 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl84,157,179 - 4,169,172 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,847,979 - 3,859,935 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,909,733 - 3,921,692 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.084,171,825 - 4,183,775 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
DHRS4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,242,124 - 75,255,598 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1775,242,121 - 75,255,594 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,512,359 - 80,525,829 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103231490
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12924,170,090 - 24,185,509 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2924,169,818 - 24,185,634 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605922,224,518 - 22,239,925 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Dhrs4
133 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:41
Count of miRNA genes:38
Interacting mature miRNAs:40
Transcripts:ENSRNOT00000024782
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152272835342072050Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat

Markers in Region
BE114851  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21528,975,446 - 28,975,617 (+)MAPPERmRatBN7.2
Rnor_6.01534,164,385 - 34,164,555NCBIRnor6.0
Rnor_5.01538,054,811 - 38,054,981UniSTSRnor5.0
RGSC_v3.41533,618,454 - 33,618,624UniSTSRGSC3.4
Celera1528,551,461 - 28,551,631UniSTS
RH 3.4 Map15260.61UniSTS
Cytogenetic Map15p13UniSTS
RH130081  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21528,977,811 - 28,977,998 (+)MAPPERmRatBN7.2
Rnor_6.01534,166,750 - 34,166,936NCBIRnor6.0
Rnor_5.01538,057,176 - 38,057,362UniSTSRnor5.0
RGSC_v3.41533,620,819 - 33,621,005UniSTSRGSC3.4
Celera1528,553,826 - 28,554,012UniSTS
RH 3.4 Map15260.81UniSTS
Cytogenetic Map15p13UniSTS
BE113024  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21528,968,298 - 28,968,515 (+)MAPPERmRatBN7.2
Rnor_6.01534,157,238 - 34,157,454NCBIRnor6.0
Rnor_5.01538,047,662 - 38,047,878UniSTSRnor5.0
RGSC_v3.41533,611,304 - 33,611,520UniSTSRGSC3.4
Celera1528,544,314 - 28,544,530UniSTS
RH 3.4 Map15260.21UniSTS
Cytogenetic Map15p13UniSTS
BE120291  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21528,970,324 - 28,970,507 (+)MAPPERmRatBN7.2
Rnor_6.01534,159,263 - 34,159,445NCBIRnor6.0
Rnor_5.01538,049,689 - 38,049,871UniSTSRnor5.0
RGSC_v3.41533,613,332 - 33,613,514UniSTSRGSC3.4
Celera1528,546,339 - 28,546,521UniSTS
RH 3.4 Map15260.81UniSTS
Cytogenetic Map15p13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000024782   ⟹   ENSRNOP00000024782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1532,936,522 - 32,948,101 (+)Ensembl
mRatBN7.2 Ensembl1528,966,553 - 28,978,127 (+)Ensembl
Rnor_6.0 Ensembl1534,155,504 - 34,167,072 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119531   ⟹   ENSRNOP00000082872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1532,936,522 - 32,947,698 (+)Ensembl
mRatBN7.2 Ensembl1528,966,553 - 28,977,730 (+)Ensembl
RefSeq Acc Id: NM_153315   ⟹   NP_695227
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81532,936,534 - 32,948,103 (+)NCBI
mRatBN7.21528,966,565 - 28,978,135 (+)NCBI
Rnor_6.01534,155,504 - 34,167,073 (+)NCBI
Rnor_5.01538,045,908 - 38,057,499 (+)NCBI
RGSC_v3.41533,609,570 - 33,621,142 (+)RGD
Celera1528,542,580 - 28,554,149 (+)RGD
Sequence:
RefSeq Acc Id: XM_039093040   ⟹   XP_038948968
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81532,936,515 - 32,946,246 (+)NCBI
mRatBN7.21528,966,544 - 28,976,256 (+)NCBI
RefSeq Acc Id: XM_063274033   ⟹   XP_063130103
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81532,924,482 - 32,948,096 (+)NCBI
RefSeq Acc Id: NP_695227   ⟸   NM_153315
- UniProtKB: Q6IRD4 (UniProtKB/Swiss-Prot),   Q8VID1 (UniProtKB/Swiss-Prot),   A0A8I5ZUW8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024782   ⟸   ENSRNOT00000024782
RefSeq Acc Id: XP_038948968   ⟸   XM_039093040
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000082872   ⟸   ENSRNOT00000119531
RefSeq Acc Id: XP_063130103   ⟸   XM_063274033
- Peptide Label: isoform X1
- UniProtKB: Q8VID1 (UniProtKB/Swiss-Prot),   Q6IRD4 (UniProtKB/Swiss-Prot),   A0A8I5ZUW8 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VID1-F1-model_v2 AlphaFold Q8VID1 1-279 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708482 AgrOrtholog
BioCyc Gene G2FUF-13725 BioCyc
Ensembl Genes ENSRNOG00000018239 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024782 ENTREZGENE
  ENSRNOT00000024782.5 UniProtKB/Swiss-Prot
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7099044 IMAGE-MGC_LOAD
InterPro NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot
  Sc_DH/Rdtase_CS UniProtKB/Swiss-Prot
  SDR_fam UniProtKB/Swiss-Prot
KEGG Report rno:266686 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91451 IMAGE-MGC_LOAD
NCBI Gene 266686 ENTREZGENE
PANTHER DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4 UniProtKB/Swiss-Prot
  PTHR43943:SF8 UniProtKB/Swiss-Prot
Pfam adh_short_C2 UniProtKB/Swiss-Prot
PhenoGen Dhrs4 PhenoGen
PRINTS GDHRDH UniProtKB/Swiss-Prot
  SDRFAMILY UniProtKB/Swiss-Prot
PROSITE ADH_SHORT UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018239 RatGTEx
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot
UniProt A0A8I5ZUW8 ENTREZGENE, UniProtKB/TrEMBL
  A6KGZ7_RAT UniProtKB/TrEMBL
  A6KGZ8_RAT UniProtKB/TrEMBL
  DHRS4_RAT UniProtKB/Swiss-Prot
  Q6IRD4 ENTREZGENE
  Q8VID1 ENTREZGENE
UniProt Secondary Q6IRD4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-01 Dhrs4  dehydrogenase/reductase 4  Dhrs4  dehydrogenase/reductase (SDR family) member 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Dhrs4  dehydrogenase/reductase (SDR family) member 4  LOC266686  carbonyl reductase  Symbol and Name updated 1299863 APPROVED