Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of NIFK mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | ISO | Nifk (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of NIFK mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | multiple interactions | ISO | Nifk (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NIFK mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | ISO | Nifk (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of NIFK mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | Nifk (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NIFK mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | affects expression | ISO | Nifk (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of NIFK mRNA | CTD | PMID:17555576 | 17beta-estradiol | affects expression | ISO | Nifk (Mus musculus) | 6480464 | Estradiol affects the expression of NIFK mRNA | CTD | PMID:15598610 | 17beta-estradiol | increases expression | ISO | NIFK (Homo sapiens) | 6480464 | Estradiol results in increased expression of NIFK mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Nifk (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NIFK mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Nifk (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NIFK mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Nifk (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NIFK mRNA | CTD | PMID:17942748 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of NIFK mRNA | CTD | PMID:21346803 | 2-amino-14,16-dimethyloctadecan-3-ol | decreases expression | ISO | NIFK (Homo sapiens) | 6480464 | 2-amino-14 and 16-dimethyloctadecan-3-ol results in decreased expression of NIFK protein | CTD | PMID:32044396 | 4,4'-sulfonyldiphenol | affects expression | ISO | NIFK (Homo sapiens) | 6480464 | bisphenol S affects the expression of NIFK protein | CTD | PMID:31945527 | 4-phenylbutyric acid | decreases expression | ISO | NIFK (Homo sapiens) | 6480464 | 4-phenylbutyric acid results in decreased expression of NIFK mRNA | CTD | PMID:14583596 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of NIFK mRNA | CTD | PMID:30047161 | aflatoxin B1 | increases expression | ISO | NIFK (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of NIFK mRNA | CTD | PMID:27153756 | all-trans-retinoic acid | decreases expression | ISO | NIFK (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of NIFK mRNA | CTD | PMID:21934132 | all-trans-retinoic acid | decreases expression | ISO | Nifk (Mus musculus) | 6480464 | Tretinoin results in decreased expression of NIFK mRNA | CTD | PMID:16604517 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of NIFK mRNA | CTD | PMID:30047161 | antirheumatic drug | decreases expression | ISO | NIFK (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of NIFK mRNA | CTD | PMID:24449571 | arsenite(3-) | multiple interactions | ISO | NIFK (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to NIFK mRNA] | CTD | PMID:32406909 | arsenous acid | increases expression | ISO | NIFK (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of NIFK mRNA | CTD | PMID:14703492 | atrazine | decreases expression | ISO | NIFK (Homo sapiens) | 6480464 | Atrazine results in decreased expression of NIFK mRNA | CTD | PMID:22378314 | benzo[a]pyrene | increases expression | ISO | Nifk (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of NIFK mRNA | CTD | PMID:22228805 | bisphenol A | decreases expression | ISO | NIFK (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of NIFK mRNA and bisphenol A results in decreased expression of NIFK protein | CTD | PMID:25047013 more ... | bisphenol A | multiple interactions | ISO | NIFK (Homo sapiens) | 6480464 | [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of NIFK protein | CTD | PMID:31629898 | bisphenol A | affects expression | ISO | NIFK (Homo sapiens) | 6480464 | bisphenol A affects the expression of NIFK mRNA | CTD | PMID:30903817 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NIFK mRNA | CTD | PMID:25181051 more ... | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of NIFK promoter | CTD | PMID:22457795 | caffeine | affects phosphorylation | ISO | NIFK (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of NIFK protein | CTD | PMID:35688186 | carbon nanotube | increases expression | ISO | Nifk (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of NIFK mRNA | CTD | PMID:25554681 | chromium(6+) | affects expression | ISO | Nifk (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of NIFK mRNA | CTD | PMID:28472532 | cisplatin | increases expression | ISO | NIFK (Homo sapiens) | 6480464 | Cisplatin results in increased expression of NIFK mRNA | CTD | PMID:19561079 | clozapine | decreases expression | ISO | NIFK (Homo sapiens) | 6480464 | Clozapine results in decreased expression of NIFK protein | CTD | PMID:34122009 | coumarin | decreases phosphorylation | ISO | NIFK (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of NIFK protein | CTD | PMID:35688186 | cyclosporin A | increases expression | ISO | Nifk (Mus musculus) | 6480464 | Cyclosporine results in increased expression of NIFK mRNA | CTD | PMID:19770486 | cyclosporin A | increases expression | ISO | NIFK (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of NIFK mRNA | CTD | PMID:20106945 and PMID:25562108 | diarsenic trioxide | increases expression | ISO | NIFK (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of NIFK mRNA | CTD | PMID:14703492 | diazinon | increases methylation | ISO | NIFK (Homo sapiens) | 6480464 | Diazinon results in increased methylation of NIFK gene | CTD | PMID:22964155 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of NIFK mRNA | CTD | PMID:21266533 | dibutyl phthalate | decreases expression | ISO | Nifk (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of NIFK mRNA | CTD | PMID:21266533 | dicrotophos | decreases expression | ISO | NIFK (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of NIFK mRNA | CTD | PMID:28302478 | dorsomorphin | multiple interactions | ISO | NIFK (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NIFK mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | NIFK (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of NIFK mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | ISO | NIFK (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of NIFK protein | CTD | PMID:23301498 | ethanol | increases expression | ISO | Nifk (Mus musculus) | 6480464 | Ethanol results in increased expression of NIFK mRNA | CTD | PMID:30319688 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of NIFK mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Nifk (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NIFK mRNA | CTD | PMID:22206623 | FR900359 | affects phosphorylation | ISO | NIFK (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of NIFK protein | CTD | PMID:37730182 | haloperidol | decreases expression | ISO | NIFK (Homo sapiens) | 6480464 | Haloperidol results in decreased expression of NIFK protein | CTD | PMID:34122009 | hydrogen peroxide | affects expression | ISO | NIFK (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of NIFK mRNA | CTD | PMID:20044591 | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of NIFK mRNA | CTD | PMID:21396975 | inulin | multiple interactions | ISO | Nifk (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of NIFK mRNA | CTD | PMID:36331819 | ivermectin | decreases expression | ISO | NIFK (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of NIFK protein | CTD | PMID:32959892 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of NIFK mRNA | CTD | PMID:30047161 | methotrexate | affects expression | ISO | Nifk (Mus musculus) | 6480464 | Methotrexate affects the expression of NIFK mRNA | CTD | PMID:18502557 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of NIFK mRNA | CTD | PMID:24136188 | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of NIFK mRNA | CTD | PMID:24136188 | paracetamol | affects expression | ISO | Nifk (Mus musculus) | 6480464 | Acetaminophen affects the expression of NIFK mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of NIFK mRNA | CTD | PMID:33387578 | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of NIFK mRNA | CTD | PMID:32680482 | perfluorononanoic acid | increases expression | ISO | NIFK (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of NIFK mRNA | CTD | PMID:32588087 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Nifk (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of NIFK mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of NIFK mRNA | CTD | PMID:36331819 | phenobarbital | increases expression | ISO | Nifk (Mus musculus) | 6480464 | Phenobarbital results in increased expression of NIFK mRNA | CTD | PMID:25270620 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of NIFK mRNA | CTD | PMID:30047161 | phenol red | multiple interactions | ISO | NIFK (Homo sapiens) | 6480464 | [Phenolsulfonphthalein deficiency co-treated with bisphenol A] results in increased expression of NIFK protein | CTD | PMID:31629898 | phorone | affects expression | EXP | | 6480464 | phorone affects the expression of NIFK mRNA | CTD | PMID:18198479 | pirinixic acid | increases expression | ISO | Nifk (Mus musculus) | 6480464 | pirinixic acid results in increased expression of NIFK mRNA | CTD | PMID:18301758 | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Nifk (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of NIFK mRNA | CTD | PMID:28903501 | quercetin | increases phosphorylation | ISO | NIFK (Homo sapiens) | 6480464 | Quercetin results in increased phosphorylation of NIFK protein | CTD | PMID:35688186 | resveratrol | multiple interactions | ISO | NIFK (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of NIFK mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | NIFK (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | senecionine | decreases expression | ISO | Nifk (Mus musculus) | 6480464 | senecionine results in decreased expression of NIFK protein | CTD | PMID:35357534 | silicon dioxide | increases expression | ISO | NIFK (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of NIFK mRNA | CTD | PMID:25895662 | sodium arsenite | multiple interactions | ISO | NIFK (Homo sapiens) | 6480464 | sodium arsenite promotes the reaction [NIFK protein binds to CAPRIN1 protein] | CTD | PMID:33939924 | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of NIFK mRNA | CTD | PMID:25993096 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of NIFK mRNA | CTD | PMID:30047161 | sunitinib | increases expression | ISO | NIFK (Homo sapiens) | 6480464 | Sunitinib results in increased expression of NIFK mRNA | CTD | PMID:31533062 | tamoxifen | affects expression | ISO | Nifk (Mus musculus) | 6480464 | Tamoxifen affects the expression of NIFK mRNA | CTD | PMID:17555576 | temozolomide | increases expression | ISO | NIFK (Homo sapiens) | 6480464 | Temozolomide results in increased expression of NIFK mRNA | CTD | PMID:31758290 | tetrachloromethane | increases expression | ISO | Nifk (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of NIFK mRNA | CTD | PMID:27339419 and PMID:31919559 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of NIFK mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of NIFK mRNA | CTD | PMID:31150632 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of NIFK mRNA | CTD | PMID:23411599 and PMID:34492290 | trichostatin A | increases expression | ISO | NIFK (Homo sapiens) | 6480464 | trichostatin A results in increased expression of NIFK mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | NIFK (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NIFK mRNA | CTD | PMID:27188386 | Triptolide | increases expression | ISO | Nifk (Mus musculus) | 6480464 | triptolide results in increased expression of NIFK mRNA | CTD | PMID:32835833 | urethane | decreases expression | ISO | NIFK (Homo sapiens) | 6480464 | Urethane results in decreased expression of NIFK mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | Nifk (Mus musculus) | 6480464 | Valproic Acid affects the expression of NIFK mRNA | CTD | PMID:17292431 | valproic acid | increases expression | ISO | NIFK (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of NIFK mRNA | CTD | PMID:23179753 | valproic acid | affects expression | ISO | NIFK (Homo sapiens) | 6480464 | Valproic Acid affects the expression of NIFK mRNA | CTD | PMID:25979313 | valproic acid | increases methylation | ISO | NIFK (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of NIFK gene | CTD | PMID:29154799 | | 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Gene Ontology Annotations Click to see Annotation Detail View
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