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Gene: Nifk (nucleolar protein interacting with the FHA domain of MKI67) Rattus norvegicus

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Symbol:

Nifk

Name:

nucleolar protein interacting with the FHA domain of MKI67

RGD ID:

708462

Description:

Predicted to enable RNA binding activity. Predicted to be located in condensed nuclear chromosome and cytoplasm. Predicted to be active in nucleolus. Orthologous to human NIFK (nucleolar protein interacting with the FHA domain of MKI67); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC246042; MGC105693; Mki67 (FHA domain) interacting nucleolar phosphoprotein; MKI67 FHA domain-interacting nucleolar phosphoprotein; Mki67ip; nucleolar protein interacting with the FHA domain of pKI-67; spermatogenesis-related protein (Srp)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	31,946,119 - 31,955,950 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	31,946,108 - 31,959,561 (+)	Ensembl				GRCr8
mRatBN7.2	13	29,393,303 - 29,403,387 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	29,393,286 - 29,405,896 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	31,978,161 - 31,987,965 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	33,265,997 - 33,275,801 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	30,537,771 - 30,547,584 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	34,267,442 - 34,277,543 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	34,267,471 - 34,277,530 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	39,397,736 - 39,407,837 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	30,944,169 - 30,953,973 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	29,298,808 - 29,308,614 (+)	NCBI		Celera
RGSC_v3.1	13	30,952,883 - 30,956,664 (-)	NCBI
Cytogenetic Map	13	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (EXP)

2-amino-14,16-dimethyloctadecan-3-ol (ISO)

4,4'-sulfonyldiphenol (ISO)

4-phenylbutyric acid (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP)

caffeine (ISO)

carbon nanotube (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

clozapine (ISO)

coumarin (ISO)

cyclosporin A (ISO)

deoxynivalenol (ISO)

diarsenic trioxide (ISO)

diazinon (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP,ISO)

dicrotophos (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

haloperidol (ISO)

hydrogen peroxide (ISO)

indole-3-methanol (EXP)

inulin (ISO)

ivermectin (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methimazole (EXP)

methotrexate (ISO)

N-ethyl-N-nitrosourea (ISO)

nefazodone (EXP)

nimesulide (EXP)

nitrates (ISO)

paracetamol (EXP,ISO)

paraquat (EXP)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (EXP,ISO)

phenol red (ISO)

phorone (EXP)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

quercetin (ISO)

resveratrol (ISO)

rotenone (ISO)

SB 431542 (ISO)

senecionine (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

sulfadimethoxine (EXP)

sunitinib (ISO)

tamoxifen (ISO)

temozolomide (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

Triptolide (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

chromosome (IEA,ISO)

condensed nuclear chromosome (IEA,ISO)

cytoplasm (IEA,ISO)

nucleolus (IBA,IEA,ISO)

nucleoplasm (IEA,ISO)

Molecular Function

nucleic acid binding (IEA)

protein binding (ISO)

RNA binding (IBA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	A novel nucleolar protein, NIFK, interacts with the forkhead associated domain of Ki-67 antigen in mitosis.	Takagi M, etal., J Biol Chem 2001 Jul 6;276(27):25386-91. Epub 2001 May 7.

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:19389623	PMID:22658674	PMID:22681889

Genomics

Comparative Map Data

Nifk
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	31,946,119 - 31,955,950 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	31,946,108 - 31,959,561 (+)	Ensembl				GRCr8
mRatBN7.2	13	29,393,303 - 29,403,387 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	29,393,286 - 29,405,896 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	31,978,161 - 31,987,965 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	33,265,997 - 33,275,801 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	30,537,771 - 30,547,584 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	34,267,442 - 34,277,543 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	34,267,471 - 34,277,530 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	39,397,736 - 39,407,837 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	30,944,169 - 30,953,973 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	29,298,808 - 29,308,614 (+)	NCBI		Celera
RGSC_v3.1	13	30,952,883 - 30,956,664 (-)	NCBI
Cytogenetic Map	13	q11	NCBI

NIFK
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	121,726,945 - 121,736,875 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	121,726,945 - 121,736,912 (-)	Ensembl			hg38	GRCh38
GRCh37	2	122,484,521 - 122,494,451 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	122,201,024 - 122,210,938 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	122,200,783 - 122,210,698	NCBI
Celera	2	115,809,158 - 115,819,140 (-)	NCBI		Celera
Cytogenetic Map	2	q14.3	NCBI
HuRef	2	114,807,419 - 114,817,401 (-)	NCBI		HuRef
CHM1_1	2	122,488,064 - 122,498,044 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	122,162,220 - 122,172,150 (-)	NCBI		T2T-CHM13v2.0

Nifk
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	118,249,573 - 118,261,561 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	118,249,569 - 118,261,552 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	118,321,843 - 118,333,831 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	118,321,839 - 118,333,822 (+)	Ensembl			mm10	GRCm38
MGSCv37	1	120,218,420 - 120,230,408 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	120,149,394 - 120,161,135 (+)	NCBI		MGSCv36	mm8
Celera	1	120,982,370 - 120,994,365 (+)	NCBI		Celera
Cytogenetic Map	1	E2.3	NCBI
cM Map	1	52.14	NCBI

Nifk
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955459	8,315,967 - 8,324,765 (+)	Ensembl
ChiLan1.0	NW_004955459	8,315,893 - 8,325,141 (+)	NCBI	ChiLan1.0	ChiLan1.0

NIFK
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	53,902,079 - 53,912,250 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	53,917,059 - 53,927,229 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	38,524,416 - 38,534,302 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	122,413,494 - 122,422,953 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	122,413,494 - 122,422,953 (-)	Ensembl			panPan2	panpan1.1

NIFK
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	19	28,486,049 - 28,498,711 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	19	28,486,062 - 28,498,151 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	19	28,744,930 - 28,756,332 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	19	29,851,968 - 29,864,625 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	19	29,851,998 - 29,864,474 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	19	28,549,245 - 28,562,206 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	19	28,719,450 - 28,732,616 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	19	29,899,819 - 29,912,784 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Nifk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	92,614,662 - 92,623,554 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936469	48,994,003 - 49,005,522 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936469	48,984,370 - 49,003,058 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NIFK
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	29,714,297 - 29,754,978 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	29,719,024 - 29,734,811 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	34,678,377 - 34,692,410 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NIFK
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	8,554,373 - 8,563,865 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	8,554,583 - 8,563,817 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666061	14,138,650 - 14,148,748 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nifk
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624732	23,470,175 - 23,478,427 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624732	23,470,077 - 23,478,795 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Nifk
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	10,880,361 - 10,890,419 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Nifk
71 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	163
Count of miRNA genes:	141
Interacting mature miRNAs:	147
Transcripts:	ENSRNOT00000061619
Prediction methods:	Microtar, Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2317027	Aia22	Adjuvant induced arthritis QTL 22	2.29		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	13	1	34785618	Rat
9589141	Insul28	Insulin level QTL 28	10.82	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	13	11866254	56866254	Rat
2317034	Aia9	Adjuvant induced arthritis QTL 9	4.62		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	12285517	34884386	Rat
61391	Bp5	Blood pressure QTL 5	5.6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	24853925	69853925	Rat
1300163	Cardf1	Cardiac cell morphology QTL 1	4.18		aorta morphology trait (VT:0000272)	artery lesion measurement (CMO:0000975)	13	12448421	47969993	Rat
2317040	Aia21	Adjuvant induced arthritis QTL 21	2.75		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	12384320	57384320	Rat
631645	Bp121	Blood pressure QTL 121	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	17468282	62468282	Rat
2303030	Bp327	Blood pressure QTL 327			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	1	43736554	Rat
2317046	Aia8	Adjuvant induced arthritis QTL 8	3.9700000286102295		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	12384320	57384320	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	7421791	87286911	Rat
2317044	Aia23	Adjuvant induced arthritis QTL 23	2.3		joint integrity trait (VT:0010548)	ankle joint diameter (CMO:0002148)	13	12285517	34884386	Rat
61339	Bp24	Blood pressure QTL 24		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	6002008	47359539	Rat
1331784	Bp222	Blood pressure QTL 222	2.944		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	24335432	55601132	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
2302275	Gluco37	Glucose level QTL 37	3.8		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	13	12448421	48744906	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
1558644	Cm45	Cardiac mass QTL 45	3.6	0.002	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	13	26244808	71244808	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	11081740	103588154	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
12879471	Bp398	Blood pressure QTL 398			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	3088755	48088755	Rat
631672	Iddm12	Insulin dependent diabetes mellitus QTL 12	2.2	0.0032	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	13	6002008	37088115	Rat
6893338	Cm76	Cardiac mass QTL 76	0	0.99	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	26244808	71244808	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	103588154	Rat
9589164	Gluco66	Glucose level QTL 66	6.67	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	13	17711336	62711336	Rat
738036	Lnnr4	Liver neoplastic nodule remodeling QTL 4	3.64		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	1	34785618	Rat
7411662	Foco29	Food consumption QTL 29	20.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	13	11866254	56866254	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_139186	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598665	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC086585	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000061619 ⟹ ENSRNOP00000058336

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	31,946,108 - 31,959,561 (+)	Ensembl
mRatBN7.2 Ensembl	13	29,393,286 - 29,405,896 (+)	Ensembl
Rnor_6.0 Ensembl	13	34,267,471 - 34,277,530 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000092802 ⟹ ENSRNOP00000076005

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	31,946,307 - 31,959,561 (+)	Ensembl
mRatBN7.2 Ensembl	13	29,393,473 - 29,405,896 (+)	Ensembl
Rnor_6.0 Ensembl	13	34,267,614 - 34,273,463 (+)	Ensembl

RefSeq Acc Id:

NM_139186 ⟹ NP_631925

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	31,946,146 - 31,955,950 (+)	NCBI
mRatBN7.2	13	29,393,328 - 29,403,132 (+)	NCBI
Rnor_6.0	13	34,267,471 - 34,277,275 (+)	NCBI
Rnor_5.0	13	39,397,736 - 39,407,837 (+)	NCBI
RGSC_v3.4	13	30,944,169 - 30,953,973 (+)	RGD
Celera	13	29,298,808 - 29,308,614 (+)	RGD

Sequence:

show sequence

CGCGTGGATTAACTTGTTCGTGCTTCTCCAGTATGGCCGAGTATTCAGGCCCTGCGAAGCCGAC
TCTGGCGTTGAACCCGCGGGAGGACTCGCAGTTTGAGAAGGATCTGACGCAAATACAACGGCGC
GCGAAAAAGAAGAAGGAAGAAAAACTTAACTCTGGAGTAGTTTATCTGGGGCACCTACCTTCAA
CGCTCTCTGAAAGCCACATCTATGACTACTGTGCCCAGTTTGGCGATATTAGAAGATTCAGATT
GTCCAGAAGTAAGCGGACTGGAAACAGCAGAGGCTTTGCCTTTGTGGAGTTTGAGTCTGAGGAT
GTTGCCAAGATAGTTGCAGAAACAATGGATAACTACCTTTTTGGTGAAAGGCTTCTATCATGTA
AATTTATGCCACGAGAAAAAGTTCATAAAGACCTTTTTAACCAGTGCAATGTTCCGTTTCATCC
GCCATCATTTCCAGCAGTGAAACGCTATAATCAGAAACGAGGACATTTGCAGATGTTAAAGATG
GAATATCGGTTTAAGAAGAAGGAAAAATTACTCAGGAAGAAACTAGCTAAGAAGGGTATTGATT
ATAGTTTTCCTTCACTGGTCCTTCCTAAGCCAAAGAAAGAGATTTCAAGCATTGCTAACACTCA
TGGGGATTCTGAGGCTAACCAGGATCCCACGCCAGTTTGTACACCAACGTTTTTGGAAAGACGG
AAATCACAGTTGATGGAAATCAATGACGATGATGAAATCATTTTGAAACTGCCTGTGTCACCAG
TGAAAGAAGACACACAAAAGACTCCAGCACCTGAAAGCTCTGGGAAAAAAAGACTGAGAAAAAG
GAAGAGCAAGCAGTGATCCTGACAGCGTTCTATGCACTTAGTTCTAGTCATATATGATCTCGTT
GTGTTTTGCTAAGTGTGGTGACATGCAAACATGGACAGGACTGTTGGAGTAAGAATACATGTTT
GATTTTCCAGTGAGGAAAGCCACCAGGGAACTGGCTGTTTTGCCCTTTCCTGTCCTGAATTTGT
CTTCAGGCTTCGTGGCTCCCTTAAGTTTACTATCCTTATGAAACTCAGGCTTAACTACCCCCAG
GAGTCTTTATGGCTGCTGGGTGCTGTTTGGACTGTATGTGGTTGTGTATATAAAAAAAACCCAA
AAAAGTGTGTCCGGCTTCAACCTCAGGCATCTGAAACTGTAAGTTAAATCCAGAGAGTGAGAGG
GCAGTCCAGGTGCTGAGGAGGAATCTGAAATGACTTGTTCTCACCCACAGTTAATTGCAGCTAA
GCTAGTGTGTAGGTTTCACAAATCGGCTTCAGCGGTTGTATTGAAGATTCAACGGTGACCAAAC
TTTTCTGCAGTTTGTGTACAAGAGAACCTAAGAGCTTGTGGGGATAATTCTAAAAAAGTCTCCA
TCTTTCTATGCTTTTGTTTTGCTAATTTGGGTTTGTTGAATATACCTATCAATCACCAAAAAAA
AAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_017598665 ⟹ XP_017454154

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	31,946,119 - 31,955,950 (+)	NCBI
mRatBN7.2	13	29,393,303 - 29,403,387 (+)	NCBI
Rnor_6.0	13	34,267,442 - 34,277,543 (+)	NCBI

Sequence:

show sequence

AGTGAAAAGAACGTCACTTCCGGAGGTTCCGCGTGGATTAACTTGTTCGTGCTTCTCCAGTATG
GCCGAGTATTCAGGCCCTGCGAAGCCGACTCTGGCGTTGAACCCGCGGGAGGACTCGCAGTTTG
AGAAGGATCTGACGCAAATACAACGGCGCGCGAAAAAGCAGAAGAAGGAAGAAAAACTTAACTC
TGGAGTAGTTTATCTGGGGCACCTACCTTCAACGCTCTCTGAAAGCCACATCTATGACTACTGT
GCCCAGTTTGGCGATATTAGAAGATTCAGATTGTCCAGAAGTAAGCGGACTGGAAACAGCAGAG
GCTTTGCCTTTGTGGAGTTTGAGTCTGAGGATGTTGCCAAGATAGTTGCAGAAACAATGGATAA
CTACCTTTTTGGTGAAAGGCTTCTATCATGTAAATTTATGCCACGAGAAAAAGTTCATAAAGAC
CTTTTTAACCAGTGCAATGTTCCGTTTCATCCGCCATCATTTCCAGCAGTGAAACGCTATAATC
AGAAACGAGGACATTTGCAGATGTTAAAGATGGAATATCGGTTTAAGAAGAAGGAAAAATTACT
CAGGAAGAAACTAGCTAAGAAGGGTATTGATTATAGTTTTCCTTCACTGGTCCTTCCTAAGCCA
AAGAAAGAGATTTCAAGCATTGCTAACACTCATGGGGATTCTGAGGCTAACCAGGATCCCACGC
CAGTTTGTACACCAACGTTTTTGGAAAGACGGAAATCACAGTTGATGGAAATCAATGACGATGA
TGAAATCATTTTGAAACTGCCTGTGTCACCAGTGAAAGAAGACACACAAAAGACTCCAGCACCT
GAAAGCTCTGGGAAAAAAAGACTGAGAAAAAGGAAGAGCAAGCAGTGATCCTGACAGCGTTCTA
TGCACTTAGTTCTAGTCATATATGATCTCGTTGTGTTTTGCTAAGTGTGGTGACATGCAAACAT
GGACAGGACTGTTGGAGTAAGAATACATGTTTGATTTTCCAGTGAGGAAAGCCACCAGGGAACT
GGCTGTTTTGCCCTTTCCTGTCCTGAATTTGTCTTCAGGCTTCGTGGCTCCCTTAAGTTTACTA
TCCTTATGAAACTCAGGCTTAACTACCCCCAGGAGTCTTTATGGCTGCTGGGTGCTGTTTGGAC
TGTATGTGGTTGTGTATATAAAAAAAACCCAAAAAAGTGTGTCCGGCTTCAACCTCAGGCATCT
GAAACTGTAAGTTAAATCCAGAGAGTGAGAGGGCAGTCCAGGTGCTGAGGAGGAATCTGAAATG
ACTTGTTCTCACCCACAGTTAATTGCAGCTAAGCTAGTGTGTAGGTTTCACAAATCGGCTTCAG
CGGTTGTATTGAAGATTCAACGGTGACCAAACTTTTCTGCAGTTTGTGTACAAGAGAACCTAAG
AGCTTGTGGGGATAATTCTAAAAAAGTCTCCATCTTTCTATGCTTTTGTTTTGCTAATTTGGGT
TTGTTGAATATACCTATCAATCACCATTAAGCATCCTTTTTGTCCAGTTGTGGGTGTGAGTGTA
AATGCTGGGTGTGCACATACACACACCTGAAGAGAAAATCAAGTGTCTTCTATCCCTCTGCCCC
TTAATCACTTGAGATAGGACTCTGGTTGGACAGTATTTCTTTATATTGTCCTGACTATTCTGGA
ACTCACTCTGTCAGACTAGTCTGATAGACTCAAGAGAGATCTACTTACCACTGCTTCCCAACTG
CTGAGATTAAAGCTGTGTGCTGCCACCAGCTGGCTTGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_631925	(Get FASTA)	NCBI Sequence Viewer
	XP_017454154	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH86585	(Get FASTA)	NCBI Sequence Viewer
	EDL87904	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000058336
GenBank Protein	Q5RJM0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_631925 ⟸ NM_139186

- UniProtKB:

Q5RJM0 (UniProtKB/Swiss-Prot), A6K7V9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAEYSGPAKPTLALNPREDSQFEKDLTQIQRRAKKKKEEKLNSGVVYLGHLPSTLSESHIYDYC
AQFGDIRRFRLSRSKRTGNSRGFAFVEFESEDVAKIVAETMDNYLFGERLLSCKFMPREKVHKD
LFNQCNVPFHPPSFPAVKRYNQKRGHLQMLKMEYRFKKKEKLLRKKLAKKGIDYSFPSLVLPKP
KKEISSIANTHGDSEANQDPTPVCTPTFLERRKSQLMEINDDDEIILKLPVSPVKEDTQKTPAP
ESSGKKRLRKRKSKQ

hide sequence

RefSeq Acc Id:	XP_017454154 ⟸ XM_017598665
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2QSI2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAEYSGPAKPTLALNPREDSQFEKDLTQIQRRAKKQKKEEKLNSGVVYLGHLPSTLSESHIYDY CAQFGDIRRFRLSRSKRTGNSRGFAFVEFESEDVAKIVAETMDNYLFGERLLSCKFMPREKVHK DLFNQCNVPFHPPSFPAVKRYNQKRGHLQMLKMEYRFKKKEKLLRKKLAKKGIDYSFPSLVLPK PKKEISSIANTHGDSEANQDPTPVCTPTFLERRKSQLMEINDDDEIILKLPVSPVKEDTQKTPA PESSGKKRLRKRKSKQ hide sequence

Ensembl Acc Id:

ENSRNOP00000076005 ⟸ ENSRNOT00000092802

Ensembl Acc Id:

ENSRNOP00000058336 ⟸ ENSRNOT00000061619

Protein Domains

RRM

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5RJM0-F1-model_v2	AlphaFold	Q5RJM0	1-271	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698759

Promoter ID:

EPDNEW_R9283

Type:

initiation region

Name:

Nifk_1

Description:

nucleolar protein interacting with the FHA domain of MKI67

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	34,267,474 - 34,267,534	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:708462	AgrOrtholog
BioCyc Gene	G2FUF-18541	BioCyc
Ensembl Genes	ENSRNOG00000025701	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000061619	ENTREZGENE
Gene3D-CATH	3.30.70.330	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7308059	IMAGE-MGC_LOAD
InterPro	NIFK_FHA_Ki67_binding	UniProtKB/Swiss-Prot
	Nucleotide-bd_a/b_plait_sf	UniProtKB/Swiss-Prot
	RBD_domain_sf	UniProtKB/Swiss-Prot
	RRM_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:246042	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105693	IMAGE-MGC_LOAD
NCBI Gene	246042	ENTREZGENE
PANTHER	MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN	UniProtKB/Swiss-Prot
Pfam	hNIFK_binding	UniProtKB/Swiss-Prot
	RRM_1	UniProtKB/Swiss-Prot
PhenoGen	Nifk	PhenoGen
PROSITE	RRM	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000025701	RatGTEx
SMART	RRM	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF54928	UniProtKB/Swiss-Prot
UniProt	A0A1B0GWS6_RAT	UniProtKB/TrEMBL
	A0A8L2QSI2	ENTREZGENE, UniProtKB/TrEMBL
	A6K7V9	ENTREZGENE, UniProtKB/TrEMBL
	MK67I_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-11-22	Nifk	nucleolar protein interacting with the FHA domain of MKI67	Mki67ip	Mki67 (FHA domain) interacting nucleolar phosphoprotein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2007-04-06		Mki67 (FHA domain) interacting nucleolar phosphoprotein	Mki67ip	spermatogenesis-related protein (Srp)	Name updated to reflect Human and Mouse nomenclature	1299863	APPROVED
2004-09-10	Mki67ip	spermatogenesis-related protein (Srp)	LOC246042		Symbol and Name updated	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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