Ldhc (lactate dehydrogenase C) - Rat Genome Database

Name: Ldhc
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Ldhc (lactate dehydrogenase C) Rattus norvegicus

Analyze

Symbol:

Ldhc

Name:

lactate dehydrogenase C

RGD ID:

69366

Description:

Predicted to enable L-lactate dehydrogenase activity. Predicted to be involved in lactate metabolic process and pyruvate catabolic process. Predicted to act upstream of or within ATP biosynthetic process; flagellated sperm motility; and lactate metabolic process. Predicted to be located in cytoplasm and motile cilium. Predicted to be active in cytosol and mitochondrion. Orthologous to human LDHC (lactate dehydrogenase C); PARTICIPATES IN cysteine and methionine metabolic pathway; gluconeogenesis pathway; glycolysis pathway; INTERACTS WITH (R)-lipoic acid; 3,4-dihydroxybenzoic acid; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

L-lactate dehydrogenase C chain; lactate dehydrogenase 3 C chain sperm specific; lactate dehydrogenase 3, C chain; lactate dehydrogenase 3, C chain, sperm specific; lactate dehydrogenase C variant 3; LDH testis subunit; LDH-C; LDH-X; Ldh3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LDHC (lactate dehydrogenase C)	HGNC	Ensembl, HomoloGene, OMA, OrthoDB, Treefam
Mus musculus (house mouse):	Ldhc (lactate dehydrogenase C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	LOC102020557 (L-lactate dehydrogenase C chain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LDHC (lactate dehydrogenase C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LDHC (lactate dehydrogenase C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	LOC101970352 (L-lactate dehydrogenase C chain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LDHC (lactate dehydrogenase C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LDHC (lactate dehydrogenase C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	LOC101715932 (L-lactate dehydrogenase C chain)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	LDHC (lactate dehydrogenase C)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Mus musculus (house mouse):	Ldhc (lactate dehydrogenase C)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ldh-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Ldh	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	106,522,140 - 106,539,649 (+)	NCBI		GRCr8
mRatBN7.2	1	97,385,984 - 97,403,382 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	97,382,379 - 97,403,378 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	102,779,292 - 102,796,202 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	111,251,274 - 111,268,186 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	104,535,059 - 104,551,715 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	102,914,875 - 102,931,843 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	102,915,191 - 102,931,839 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	103,989,930 - 104,006,583 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	97,418,622 - 97,435,275 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	97,496,732 - 97,513,382 (+)	NCBI
Celera	1	91,633,230 - 91,649,970 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

hypertrophic cardiomyopathy 12 (ISO)

intellectual disability (ISO)

lung disease (ISO)

male infertility (ISO)

progressive myoclonus epilepsy 7 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(R)-lipoic acid (EXP)

1,2-dichloroethane (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,4-dihydroxybenzoic acid (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

bisphenol A (ISO)

Butoxyacetic acid (EXP)

cadmium atom (ISO)

cadmium dichloride (EXP)

CGP 52608 (ISO)

chlorpromazine (EXP)

chlorpyrifos (EXP)

coenzyme Q10 (EXP)

decabromodiphenyl ether (EXP)

dextran sulfate (ISO)

dibutyl phthalate (ISO)

dimethyl sulfoxide (ISO)

Ethoxyacetic acid (EXP)

fenvalerate (EXP)

formaldehyde (ISO)

gentamycin (EXP)

gingerol (ISO)

graphite (EXP)

lead nitrate (EXP)

lipoic acid (EXP)

lipopolysaccharide (EXP)

methimazole (EXP)

methoxyacetic acid (EXP)

microcystin RR (ISO)

Nandrolone decanoate (EXP)

ochratoxin A (ISO)

ozone (ISO)

paracetamol (EXP)

phenobarbital (ISO)

picrotoxin (EXP)

potassium dichromate (ISO)

silicon dioxide (EXP)

sodium arsenite (ISO)

sodium dichromate (EXP)

sodium fluoride (ISO)

sodium nitrate (EXP)

sulfasalazine (ISO)

tamoxifen (ISO)

taurine (EXP)

toxaphene (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ATP biosynthetic process (ISO)

carboxylic acid metabolic process (IEA)

flagellated sperm motility (ISO)

lactate biosynthetic process from pyruvate (ISO)

lactate metabolic process (IBA,IEA)

lactate oxidation (ISO)

pyruvate catabolic process (ISO)

pyruvate metabolic process (IBA,ISO)

Cellular Component

cilium (ISO)

cytoplasm (IEA,ISO)

cytosol (ISO)

mitochondrion (IBA)

motile cilium (ISO)

Molecular Function

L-lactate dehydrogenase activity (IBA,IEA,ISO)

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

cysteine and methionine metabolic pathway (IEA)

gluconeogenesis pathway (IEA)

glycolysis pathway (IEA)

glycolysis/gluconeogenesis pathway (IEA)

propanoate metabolic pathway (IEA)

pyruvate metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	KEGG: Kyoto Encyclopedia of Genes and Genomes	KEGG
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
9.	Evolutionary relationships of lactate dehydrogenases (LDHs) from mammals, birds, an amphibian, fish, barley, and bacteria: LDH cDNA sequences from Xenopus, pig, and rat.	Tsuji S, etal., Proc Natl Acad Sci U S A 1994 Sep 27;91(20):9392-6.

Additional References at PubMed

PMID:1996957	PMID:6343385	PMID:11276087	PMID:16687649	PMID:18367675	PMID:21630459	PMID:22537060	PMID:23533145	PMID:31904090

Genomics

Comparative Map Data

Ldhc
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	106,522,140 - 106,539,649 (+)	NCBI		GRCr8
mRatBN7.2	1	97,385,984 - 97,403,382 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	97,382,379 - 97,403,378 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	102,779,292 - 102,796,202 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	111,251,274 - 111,268,186 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	104,535,059 - 104,551,715 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	102,914,875 - 102,931,843 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	102,915,191 - 102,931,839 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	103,989,930 - 104,006,583 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	97,418,622 - 97,435,275 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	97,496,732 - 97,513,382 (+)	NCBI
Celera	1	91,633,230 - 91,649,970 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

LDHC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	18,412,318 - 18,452,063 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	18,412,318 - 18,452,063 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	18,433,865 - 18,473,610 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	18,390,429 - 18,429,366 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	18,390,482 - 18,429,366	NCBI
Celera	11	18,568,783 - 18,608,411 (+)	NCBI		Celera
Cytogenetic Map	11	p15.1	NCBI
HuRef	11	18,119,079 - 18,158,522 (+)	NCBI		HuRef
CHM1_1	11	18,433,317 - 18,472,228 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	18,510,444 - 18,550,172 (+)	NCBI		T2T-CHM13v2.0

Ldhc
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	46,510,687 - 46,527,571 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	46,510,627 - 46,527,566 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	46,861,263 - 46,878,147 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	46,861,203 - 46,878,142 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	54,116,633 - 54,133,512 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	46,729,305 - 46,746,184 (+)	NCBI		MGSCv36	mm8
Celera	7	42,341,209 - 42,358,089 (+)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	30.6	NCBI

LOC102020557
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	33,110,120 - 33,138,756 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955414	33,109,535 - 33,138,756 (+)	NCBI	ChiLan1.0	ChiLan1.0

LDHC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	20,729,119 - 20,768,321 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	20,689,477 - 20,728,675 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	18,450,117 - 18,489,321 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	18,132,829 - 18,172,055 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	18,132,829 - 18,172,055 (+)	Ensembl	panpan1.1		panPan2

LDHC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	40,844,644 - 40,890,407 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	40,844,662 - 40,890,398 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	40,324,373 - 40,369,674 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	41,966,636 - 42,012,586 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	41,966,655 - 42,012,233 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	40,960,921 - 41,006,005 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	41,149,688 - 41,192,528 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	41,527,202 - 41,570,252 (+)	NCBI		UU_Cfam_GSD_1.0

LOC101970352
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	44,793,662 - 44,828,879 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936528	827,758 - 862,393 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936528	827,322 - 862,832 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LDHC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	40,748,863 - 40,809,692 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	40,748,567 - 40,810,114 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	43,655,396 - 43,730,838 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LDHC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	46,480,425 - 46,528,307 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	143,836,012 - 143,883,405 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

LOC101715932
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624766	9,886,618 - 9,921,535 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624766	9,882,494 - 9,943,079 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ldhc
70 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	21
Count of miRNA genes:	21
Interacting mature miRNAs:	21
Transcripts:	ENSRNOT00000017851
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	22340647	102268831	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	30882023	123479925	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
2313051	Bss57	Bone structure and strength QTL 57	3.7	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	43284731	118944897	Rat
2313059	Bss55	Bone structure and strength QTL 55	3.2	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
2313072	Bss53	Bone structure and strength QTL 53	4.3	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	43284731	118944897	Rat
2313078	Bss54	Bone structure and strength QTL 54	3.5	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
2313094	Bss58	Bone structure and strength QTL 58	3.7	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	43284731	118944897	Rat
2313098	Bmd70	Bone mineral density QTL 70	3.6	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	43284731	118944897	Rat
2313099	Bss56	Bone structure and strength QTL 56	2.4	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	1	43284731	118944897	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	48963584	144267916	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	56732668	98773277	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	56949932	101949932	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	57336763	151090257	Rat
1300121	Hrtrt1	Heart rate QTL 1	3.7		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	65789093	115540829	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	66023617	118608521	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	77494165	122494165	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	77857876	122857876	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	77876254	106047988	Rat
61344	Bp29	Blood pressure QTL 29	7.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	78350581	123350581	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	78430536	123430536	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	78479925	123479925	Rat
4889494	Scort2	Serum corticosterone level QTL 2	4.2		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	80592172	125592172	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	82174743	118944897	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)	1	83547917	128547917	Rat
2300324	Fetw1	Fetal weight QTL 1	12.1	0.005	fetal growth trait (VT:0004201)	fetal body weight (CMO:0002080)	1	85424647	100358001	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	87580395	150700247	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	90508614	173018436	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	90508614	180359386	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	90532338	123479925	Rat
1300153	Bp171	Blood pressure QTL 171	3.37		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	90664883	143200202	Rat
2293142	Bp314	Blood pressure QTL 314			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	92184926	137184926	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	92948896	144267916	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	94494440	117601394	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94494440	172949803	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	94494440	181830018	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	94494440	198211706	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	94494440	198324465	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642644	214537671	Rat

Markers in Region

BE120592

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	97,403,178 - 97,403,337 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	102,931,640 - 102,931,798	NCBI	Rnor6.0
Rnor_5.0	1	104,006,380 - 104,006,538	UniSTS	Rnor5.0
RGSC_v3.4	1	97,435,072 - 97,435,230	UniSTS	RGSC3.4
Celera	1	91,649,767 - 91,649,925	UniSTS
RH 3.4 Map	1	909.8	UniSTS
Cytogenetic Map	1	q22	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium											7
Low			17	6	13	6	2	2	1	21	15	11	2
Below cutoff	2	11	31	26	5	26	6	9	18	12	10		6

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_017266	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229233	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759345	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109646	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC099150	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JQ173138	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JQ173139	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JQ173140	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JQ173141	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JQ409364	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JQ409365	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JQ409366	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JQ409367	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JQ409368	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JQ409369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U07177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000017851 ⟹ ENSRNOP00000017851

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	97,386,727 - 97,403,378 (+)	Ensembl
Rnor_6.0 Ensembl	1	102,915,191 - 102,931,839 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000079440 ⟹ ENSRNOP00000069268

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	97,386,727 - 97,403,378 (+)	Ensembl
Rnor_6.0 Ensembl	1	102,915,655 - 102,931,774 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000082718 ⟹ ENSRNOP00000071562

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	97,382,379 - 97,401,823 (+)	Ensembl
Rnor_6.0 Ensembl	1	102,915,655 - 102,930,272 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000083079 ⟹ ENSRNOP00000070991

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	97,382,379 - 97,403,246 (+)	Ensembl
Rnor_6.0 Ensembl	1	102,915,655 - 102,931,774 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000088892 ⟹ ENSRNOP00000073654

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	97,387,191 - 97,403,378 (+)	Ensembl
Rnor_6.0 Ensembl	1	102,915,655 - 102,931,774 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000090520 ⟹ ENSRNOP00000075021

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	97,382,379 - 97,394,469 (+)	Ensembl
Rnor_6.0 Ensembl	1	102,915,655 - 102,922,930 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000092180 ⟹ ENSRNOP00000072576

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	97,382,379 - 97,403,313 (+)	Ensembl
Rnor_6.0 Ensembl	1	102,915,655 - 102,931,774 (+)	Ensembl

RefSeq Acc Id:

NM_017266 ⟹ NP_058962

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	106,522,995 - 106,539,649 (+)	NCBI
mRatBN7.2	1	97,386,727 - 97,403,382 (+)	NCBI
Rnor_6.0	1	102,915,191 - 102,931,843 (+)	NCBI
Rnor_5.0	1	103,989,930 - 104,006,583 (+)	NCBI
RGSC_v3.4	1	97,418,622 - 97,435,275 (+)	RGD
Celera	1	91,633,230 - 91,649,970 (+)	RGD

Sequence:

show sequence

CCTGGGCCTAACGGTCATCCTTGTTTCTTAACTGCTGCGGGGTGTGTTTTCGACATCCTTTGAG
GAAGTGGGCAGTGCCTTCATCCACCTGTGAAGGCTCAACATGTCCACTGTCAAGGAGCAGCTAA
TTCAGAACCTAGCTCCAGATGAAAAACAATCCCGGTGTAAGATCACTGTGGTCGGAGTTGGAAA
TGTGGGCATGGCGTGTGCCATTAGTATTTTACTGAAGGGTCTGGCTGATGAACTTGCCCTTGTT
GATGCTGATGAGAACAAACTGAAGGGAGAGGCACTGGATCTTCTGCATGGCAGCCTTTTCCTCA
GCACTCCAAAAATCGTCTTTGGAAAAGATTACAGTGTATCTGCCAACTCCAAACTGGTTATTAT
CACTGCTGGTGCAAGAATGGTGAGTGGAGAATCTCGTCTTGCCCTGCTCCAACGTAATGTCACT
ATCATGAAAGCCATCGTTCCCGGCGTAATCCAAAACAGTCCGGACTGTAAAATAATGATTGTCA
CAAACCCAGTCGATATTTTGACATACGTGGTTTGGAAGATAAGTGGCCTCCCTGTAAGCAGTGT
GATTGGAAGTGGCTGTAACCTAGACTCCGCTCGTTTCCGTTACCTGATTGGAGAGAAGCTGGGT
GTCAACCCTTCGAGCTGCCATGGCTGGGTTCTTGGAGAACATGGGGACTCCAGTGTGCCCATAT
GGAGTGGTGTGAACATTGCTGGCGTAACTCTGAAGTCACTGAACCCAGCAATAGGATCCGACTC
CGATAAGGAACAGTGGAAAACCGTTCACAAGCAGGTGGTGGATGGTGGCTATGAGGTCCTTAAC
CTGAAGGGCTATACCTCTTGGGCCATTGCGCTGTCTGTGACTGATATCGCTGCATCAATCTTGA
AGAATCTTAAGAGGGTGCATGCTGTTACTACGCTGGTTAAGGGCTTATATGGGATAAAGGAAGA
AATCTTCCTCAGTATCCCGTGTGTCTTGGGACAAAGTGGCATCACAGACCTTGTGAAAGTCAAC
ATGAACACCGAGGAGGAAGCTCTTTTTAAGAAGAGTTGCGACATACTCTGGAACATCCAGAAAG
ATCTGCAATTATAAAGTCTGCACCTTCGACTGTTTGATAACCACCATCATTCATAAATTCAATA
AAAGTTTGGAAACCTAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006229233 ⟹ XP_006229295

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	106,523,139 - 106,539,649 (+)	NCBI
mRatBN7.2	1	97,386,843 - 97,403,382 (+)	NCBI
Rnor_6.0	1	102,915,312 - 102,931,843 (+)	NCBI
Rnor_5.0	1	103,989,930 - 104,006,583 (+)	NCBI

Sequence:

show sequence

GGGAGGGAGGAGCCTAAAGGGAGGGAGGGGCCTGTGGCCACAAGTCATCCTTTGCCTCCTTGGG
GCTTCACTTCACTCCCATACTCTAGCTAGGGAACAGTTTCGCTTCCCTGGTTCCCTGGCTCCTG
TGCTCTGGGAACTGGAGAAGTAACTCCTAGACAGGCTCAACATGTCCACTGTCAAGGAGCAGCT
AATTCAGAACCTAGCTCCAGATGAAAAACAATCCCGGTGTAAGATCACTGTGGTCGGAGTTGGA
AATGTGGGCATGGCGTGTGCCATTAGTATTTTACTGAAGGGTCTGGCTGATGAACTTGCCCTTG
TTGATGCTGATGAGAACAAACTGAAGGGAGAGGCACTGGATCTTCTGCATGGCAGCCTTTTCCT
CAGCACTCCAAAAATCGTCTTTGGAAAAGATTACAGTGTATCTGCCAACTCCAAACTGGTTATT
ATCACTGCTGGTGCAAGAATGGTGAGTGGAGAATCTCGTCTTGCCCTGCTCCAACGTAATGTCA
CTATCATGAAAGCCATCGTTCCCGGCGTAATCCAAAACAGTCCGGACTGTAAAATAATGATTGT
CACAAACCCAGTCGATATTTTGACATACGTGGTTTGGAAGATAAGTGGCCTCCCTGTAAGCAGT
GTGATTGGAAGTGGCTGTAACCTAGACTCCGCTCGTTTCCGTTACCTGATTGGAGAGAAGCTGG
GTGTCAACCCTTCGAGCTGCCATGGCTGGGTTCTTGGAGAACATGGGGACTCCAGTGTGCCCAT
ATGGAGTGGTGTGAACATTGCTGGCGTAACTCTGAAGTCACTGAACCCAGCAATAGGATCCGAC
TCCGATAAGGAACAGTGGAAAACCGTTCACAAGCAGGTGGTGGATGGTGGCTATGAGGTCCTTA
ACCTGAAGGGCTATACCTCTTGGGCCATTGCGCTGTCTGTGACTGATATCGCTGCATCAATCTT
GAAGAATCTTAAGAGGGTGCATGCTGTTACTACGCTGGTTAAGGGCTTATATGGGATAAAGGAA
GAAATCTTCCTCAGTATCCCGTGTGTCTTGGGACAAAGTGGCATCACAGACCTTGTGAAAGTCA
ACATGAACACCGAGGAGGAAGCTCTTTTTAAGAAGAGTTGCGACATACTCTGGAACATCCAGAA
AGATCTGCAATTATAAAGTCTGCACCTTCGACTGTTTGATAACCACCATCATTCATAAATTCAA
TAAAAGTTTGGAAACCTAAAA

hide sequence

RefSeq Acc Id:

XM_008759344 ⟹ XP_008757566

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	106,522,751 - 106,539,649 (+)	NCBI
mRatBN7.2	1	97,386,475 - 97,403,382 (+)	NCBI
Rnor_6.0	1	102,914,878 - 102,931,843 (+)	NCBI

Sequence:

show sequence

GCCCCCAACTCTCAGTGCCTACAAACAGATGTAAGGTATGCTCCTCAAACTCTGCATTTCCTCA
CAGGGGAAAAGCAGCCCAGTTAATGTTCGGGCCTTTAAAGGGGCGCTTGCCTAACTCACTGCCA
TTTGCGTGGTCTCAGTGCCTACACATCTTCCAGTAGAGGCCTTGGAAACCTTCTAGAGTCCGTT
TCCTAAAACATGAGGCTCAACATGTCCACTGTCAAGGAGCAGCTAATTCAGAACCTAGCTCCAG
ATGAAAAACAATCCCGGTGTAAGATCACTGTGGTCGGAGTTGGAAATGTGGGCATGGCGTGTGC
CATTAGTATTTTACTGAAGGGTCTGGCTGATGAACTTGCCCTTGTTGATGCTGATGAGAACAAA
CTGAAGGGAGAGGCACTGGATCTTCTGCATGGCAGCCTTTTCCTCAGCACTCCAAAAATCGTCT
TTGGAAAAGATTACAGTGTATCTGCCAACTCCAAACTGGTTATTATCACTGCTGGTGCAAGAAT
GGTGAGTGGAGAATCTCGTCTTGCCCTGCTCCAACGTAATGTCACTATCATGAAAGCCATCGTT
CCCGGCGTAATCCAAAACAGTCCGGACTGTAAAATAATGATTGTCACAAACCCAGTCGATATTT
TGACATACGTGGTTTGGAAGATAAGTGGCCTCCCTGTAAGCAGTGTGATTGGAAGTGGCTGTAA
CCTAGACTCCGCTCGTTTCCGTTACCTGATTGGAGAGAAGCTGGGTGTCAACCCTTCGAGCTGC
CATGGCTGGGTTCTTGGAGAACATGGGGACTCCAGTGTGCCCATATGGAGTGGTGTGAACATTG
CTGGCGTAACTCTGAAGTCACTGAACCCAGCAATAGGATCCGACTCCGATAAGGAACAGTGGAA
AACCGTTCACAAGCAGGTGGTGGATGGTGGCTATGAGGTCCTTAACCTGAAGGGCTATACCTCT
TGGGCCATTGCGCTGTCTGTGACTGATATCGCTGCATCAATCTTGAAGAATCTTAAGAGGGTGC
ATGCTGTTACTACGCTGGTTAAGGGCTTATATGGGATAAAGGAAGAAATCTTCCTCAGTATCCC
GTGTGTCTTGGGACAAAGTGGCATCACAGACCTTGTGAAAGTCAACATGAACACCGAGGAGGAA
GCTCTTTTTAAGAAGAGTTGCGACATACTCTGGAACATCCAGAAAGATCTGCAATTATAAAGTC
TGCACCTTCGACTGTTTGATAACCACCATCATTCATAAATTCAATAAAAGTTTGGAAACCTAAA
A

hide sequence

RefSeq Acc Id:

XM_017589063 ⟹ XP_017444552

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	106,528,117 - 106,539,649 (+)	NCBI
mRatBN7.2	1	97,387,184 - 97,403,382 (+)	NCBI
Rnor_6.0	1	102,915,655 - 102,931,843 (+)	NCBI

Sequence:

show sequence

ATGTCCACTGTCAAGGAGCAGCTAATTCAGAACCTAGCTCCAGATGAAAAACAATCCCGGTGTA
AGATCACTGTGGTCGGAGTTGGAAATGTGGGCATGGCGTGTGCCATTAGTATTTTACTGAAGGG
TCTGGCTGATGAACTTGCCCTTGTTGATGCTGATGAGAACAAACTGAAGGGAGAGGCACTGGAT
CTTCTGCATGGCAGCCTTTTCCTCAGCACTCCAAAAATCGTCTTTGGAAAAGAGACCAAAGGCA
TGGAATCCCCTGGATCTGAAGTTAGGGAGCCAGCAGTTGTGGGTGCTGAGAACTGAACTTGGAT
TTATTTTGAAGAGCAATTACAGTGTATCTGCCAACTCCAAACTGGTTATTATCACTGCTGGTGC
AAGAATGGTGAGTGGAGAATCTCGTCTTGCCCTGCTCCAACGTAATGTCACTATCATGAAAGCC
ATCGTTCCCGGCGTAATCCAAAACAGTCCGGACTGTAAAATAATGATTGTCACAAACCCAGTCG
ATATTTTGACATACGTGGTTTGGAAGATAAGTGGCCTCCCTGTAAGCAGTGTGATTGGAAGTGG
CTGTAACCTAGACTCCGCTCGTTTCCGTTACCTGATTGGAGAGAAGCTGGGTGTCAACCCTTCG
AGCTGCCATGGCTGGGTTCTTGGAGAACATGGGGACTCCAGTGTGCCCATATGGAGTGGTGTGA
ACATTGCTGGCGTAACTCTGAAGTCACTGAACCCAGCAATAGGATCCGACTCCGATAAGGAACA
GTGGAAAACCGTTCACAAGCAGGTGGTGGATGGTGGCTATGAGGTCCTTAACCTGAAGGGCTAT
ACCTCTTGGGCCATTGCGCTGTCTGTGACTGATATCGCTGCATCAATCTTGAAGAATCTTAAGA
GGGTGCATGCTGTTACTACGCTGGTTAAGGGCTTATATGGGATAAAGGAAGAAATCTTCCTCAG
TATCCCGTGTGTCTTGGGACAAAGTGGCATCACAGACCTTGTGAAAGTCAACATGAACACCGAG
GAGGAAGCTCTTTTTAAGAAGAGTTGCGACATACTCTGGAACATCCAGAAAGATCTGCAATTAT
AAAGTCTGCACCTTCGACTGTTTGATAACCACCATCATTCATAAATTCAATAAAAGTTTGGAAA
CCTAAAA

hide sequence

RefSeq Acc Id:

XM_039109646 ⟹ XP_038965574

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	106,522,140 - 106,539,649 (+)	NCBI
mRatBN7.2	1	97,385,984 - 97,403,382 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_058962	(Get FASTA)	NCBI Sequence Viewer
	XP_006229295	(Get FASTA)	NCBI Sequence Viewer
	XP_008757566	(Get FASTA)	NCBI Sequence Viewer
	XP_017444552	(Get FASTA)	NCBI Sequence Viewer
	XP_038965574	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA50435	(Get FASTA)	NCBI Sequence Viewer
	AAH78862	(Get FASTA)	NCBI Sequence Viewer
	AFF19212	(Get FASTA)	NCBI Sequence Viewer
	AFI54976	(Get FASTA)	NCBI Sequence Viewer
	AFI54977	(Get FASTA)	NCBI Sequence Viewer
	AFI54978	(Get FASTA)	NCBI Sequence Viewer
	AFI54979	(Get FASTA)	NCBI Sequence Viewer
	AFI54980	(Get FASTA)	NCBI Sequence Viewer
	AFI54981	(Get FASTA)	NCBI Sequence Viewer
	EDM07248	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000017851
	ENSRNOP00000017851.3
	ENSRNOP00000069268.1
	ENSRNOP00000070991.2
	ENSRNOP00000071562.2
	ENSRNOP00000072576.2
	ENSRNOP00000073654.1
	ENSRNOP00000075021.1
GenBank Protein	P19629	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_058962 ⟸ NM_017266

- UniProtKB:

P19629 (UniProtKB/Swiss-Prot), Q6AYX2 (UniProtKB/TrEMBL), A6JBD6 (UniProtKB/TrEMBL), F7FDE8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSTVKEQLIQNLAPDEKQSRCKITVVGVGNVGMACAISILLKGLADELALVDADENKLKGEALD
LLHGSLFLSTPKIVFGKDYSVSANSKLVIITAGARMVSGESRLALLQRNVTIMKAIVPGVIQNS
PDCKIMIVTNPVDILTYVVWKISGLPVSSVIGSGCNLDSARFRYLIGEKLGVNPSSCHGWVLGE
HGDSSVPIWSGVNIAGVTLKSLNPAIGSDSDKEQWKTVHKQVVDGGYEVLNLKGYTSWAIALSV
TDIAASILKNLKRVHAVTTLVKGLYGIKEEIFLSIPCVLGQSGITDLVKVNMNTEEEALFKKSC
DILWNIQKDLQL

hide sequence

RefSeq Acc Id:	XP_006229295 ⟸ XM_006229233
- Peptide Label:	isoform X3
- UniProtKB:	P19629 (UniProtKB/Swiss-Prot), Q6AYX2 (UniProtKB/TrEMBL), A6JBD6 (UniProtKB/TrEMBL), F7FDE8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSTVKEQLIQNLAPDEKQSRCKITVVGVGNVGMACAISILLKGLADELALVDADENKLKGEALD LLHGSLFLSTPKIVFGKDYSVSANSKLVIITAGARMVSGESRLALLQRNVTIMKAIVPGVIQNS PDCKIMIVTNPVDILTYVVWKISGLPVSSVIGSGCNLDSARFRYLIGEKLGVNPSSCHGWVLGE HGDSSVPIWSGVNIAGVTLKSLNPAIGSDSDKEQWKTVHKQVVDGGYEVLNLKGYTSWAIALSV TDIAASILKNLKRVHAVTTLVKGLYGIKEEIFLSIPCVLGQSGITDLVKVNMNTEEEALFKKSC DILWNIQKDLQL hide sequence

RefSeq Acc Id:	XP_008757566 ⟸ XM_008759344
- Peptide Label:	isoform X2
- UniProtKB:	P19629 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MRLNMSTVKEQLIQNLAPDEKQSRCKITVVGVGNVGMACAISILLKGLADELALVDADENKLKG EALDLLHGSLFLSTPKIVFGKDYSVSANSKLVIITAGARMVSGESRLALLQRNVTIMKAIVPGV IQNSPDCKIMIVTNPVDILTYVVWKISGLPVSSVIGSGCNLDSARFRYLIGEKLGVNPSSCHGW VLGEHGDSSVPIWSGVNIAGVTLKSLNPAIGSDSDKEQWKTVHKQVVDGGYEVLNLKGYTSWAI ALSVTDIAASILKNLKRVHAVTTLVKGLYGIKEEIFLSIPCVLGQSGITDLVKVNMNTEEEALF KKSCDILWNIQKDLQL hide sequence

RefSeq Acc Id:	XP_017444552 ⟸ XM_017589063
- Peptide Label:	isoform X4
- UniProtKB:	P19629 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MAAFSSALQKSSLEKRPKAWNPLDLKLGSQQLWVLRTELGFILKSNYSVSANSKLVIITAGARM VSGESRLALLQRNVTIMKAIVPGVIQNSPDCKIMIVTNPVDILTYVVWKISGLPVSSVIGSGCN LDSARFRYLIGEKLGVNPSSCHGWVLGEHGDSSVPIWSGVNIAGVTLKSLNPAIGSDSDKEQWK TVHKQVVDGGYEVLNLKGYTSWAIALSVTDIAASILKNLKRVHAVTTLVKGLYGIKEEIFLSIP CVLGQSGITDLVKVNMNTEEEALFKKSCDILWNIQKDLQL hide sequence

RefSeq Acc Id:

ENSRNOP00000069268 ⟸ ENSRNOT00000079440

RefSeq Acc Id:

ENSRNOP00000071562 ⟸ ENSRNOT00000082718

RefSeq Acc Id:

ENSRNOP00000072576 ⟸ ENSRNOT00000092180

RefSeq Acc Id:

ENSRNOP00000070991 ⟸ ENSRNOT00000083079

RefSeq Acc Id:

ENSRNOP00000075021 ⟸ ENSRNOT00000090520

RefSeq Acc Id:

ENSRNOP00000073654 ⟸ ENSRNOT00000088892

RefSeq Acc Id:

ENSRNOP00000017851 ⟸ ENSRNOT00000017851

RefSeq Acc Id:	XP_038965574 ⟸ XM_039109646
- Peptide Label:	isoform X1

Protein Domains

Lactate/malate dehydrogenase C-terminal Lactate/malate dehydrogenase N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P19629-F1-model_v2	AlphaFold	P19629	1-332	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690069

Promoter ID:

EPDNEW_R593

Type:

initiation region

Name:

Ldhc_1

Description:

lactate dehydrogenase C

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R594

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	102,915,207 - 102,915,267	EPDNEW

RGD ID:

13690072

Promoter ID:

EPDNEW_R594

Type:

single initiation site

Name:

Ldhc_2

Description:

lactate dehydrogenase C

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R593

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	102,915,627 - 102,915,687	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:69366	AgrOrtholog
BioCyc Gene	G2FUF-59603	BioCyc
BioCyc Pathway	PWY-5031 [L-histidine degradation V]	BioCyc
BioCyc Pathway Image	PWY-5031	BioCyc
Ensembl Genes	ENSRNOG00000013103	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000017851	ENTREZGENE
	ENSRNOT00000017851.7	UniProtKB/TrEMBL
	ENSRNOT00000079440.2	UniProtKB/TrEMBL
	ENSRNOT00000082718.2	UniProtKB/TrEMBL
	ENSRNOT00000083079.2	UniProtKB/TrEMBL
	ENSRNOT00000088892.2	UniProtKB/TrEMBL
	ENSRNOT00000090520.2	UniProtKB/TrEMBL
	ENSRNOT00000092180.2	UniProtKB/TrEMBL
Gene3D-CATH	3.90.110.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NAD(P)-binding Rossmann-like Domain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7131609	IMAGE-MGC_LOAD
InterPro	L-lactate/malate_DH	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	L-lactate_DH	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	L-lactate_DH_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Lactate/malate_DH_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Lactate/malate_DH_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Lactate_DH/Glyco_Ohase_4_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NAD(P)-bd_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:29634	UniProtKB/TrEMBL
MGC_CLONE	MGC:93523	IMAGE-MGC_LOAD
NCBI Gene	29634	ENTREZGENE
PANTHER	L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+))	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	L-LACTATE DEHYDROGENASE C CHAIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Ldh_1_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ldh_1_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ldhc	PhenoGen
PIRSF	Lac_mal_DH	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	LLDHDRGNASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	L_LDH	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROKAR_LIPOPROTEIN	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000013103	RatGTEx
Superfamily-SCOP	SSF51735	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF56327	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR	TC234106
UniProt	A0A0G2JZC1_RAT	UniProtKB/TrEMBL
	A0A0G2K0S3_RAT	UniProtKB/TrEMBL
	A0A0G2K3B9_RAT	UniProtKB/TrEMBL
	A6JBD6	ENTREZGENE, UniProtKB/TrEMBL
	F7FDE8	ENTREZGENE, UniProtKB/TrEMBL
	H9N9H4_RAT	UniProtKB/TrEMBL
	I1VWM9_RAT	UniProtKB/TrEMBL
	I1VWN0_RAT	UniProtKB/TrEMBL
	I1VWN1_RAT	UniProtKB/TrEMBL
	LDHC_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q6AYX2	ENTREZGENE
UniProt Secondary	Q6AYX2	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Ldhc	lactate dehydrogenase C		lactate dehydrogenase 3, C chain	Name updated	1299863	APPROVED
2002-06-10	Ldhc	lactate dehydrogenase 3, C chain			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in testis	68808

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

BioCyc Pathways

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

BioCyc Pathways