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Gene: Slc5a7 (solute carrier family 5 member 7) Rattus norvegicus

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Symbol:

Slc5a7

Name:

solute carrier family 5 member 7

RGD ID:

69270

Description:

Enables choline transmembrane transporter activity. Involved in acetylcholine biosynthetic process and choline transport. Located in several cellular components, including cytoplasmic vesicle; perikaryon; and plasma membrane raft. Biomarker of asthma. Human ortholog(s) of this gene implicated in autosomal dominant distal hereditary motor neuronopathy 7; congenital myasthenic syndrome 20; and depressive disorder. Orthologous to human SLC5A7 (solute carrier family 5 member 7); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH (S)-nicotine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

CHT; Cht1; hemicholinium-3-sensitive choline transporter; high affinity choline transporter 1; rCHT1; solute carrier family 5 (choline transporter) member 7; solute carrier family 5 (choline transporter), member 7; solute carrier family 5 (sodium/choline cotransporter), member 7; solute carrier family 5, member 7

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC5A7 (solute carrier family 5 member 7)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Slc5a7 (solute carrier family 5 (choline transporter), member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc5a7 (solute carrier family 5 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC5A7 (solute carrier family 5 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC5A7 (solute carrier family 5 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc5a7 (solute carrier family 5 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC5A7 (solute carrier family 5 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC5A7 (solute carrier family 5 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc5a7 (solute carrier family 5 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Slc5a7 (solute carrier family 5 member 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	OGA (O-GlcNAcase)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Slc5a7 (solute carrier family 5 (choline transporter), member 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SLC5A7 (solute carrier family 5 member 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	slc5a7a (solute carrier family 5 member 7a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	cho-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG7708	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	slc5a7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	7,922,693 - 7,953,509 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	7,922,697 - 7,953,509 (-)	Ensembl				GRCr8
mRatBN7.2	9	7,595,440 - 7,626,258 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	7,595,444 - 7,626,258 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	10,642,717 - 10,673,490 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	14,881,214 - 14,911,984 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	13,632,603 - 13,663,363 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	5,294,377 - 5,330,822 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	5,294,381 - 5,330,815 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	4,342,128 - 4,379,724 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	133,838 - 165,943 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	3,418,007 - 3,448,801 (-)	NCBI		Celera
RGSC_v3.1	9	133,837 - 165,939 (+)	NCBI
Cytogenetic Map	9	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

asthma (IEP)

autosomal dominant distal hereditary motor neuronopathy 7 (ISO)

Charcot-Marie-Tooth disease (ISO)

Charcot-Marie-Tooth disease type 2 (ISO)

congenital myasthenic syndrome (ISO)

congenital myasthenic syndrome 20 (ISO)

depressive disorder (ISO)

genetic disease (ISO)

major depressive disorder (ISO)

prostate cancer (ISO)

spinal muscular atrophy (ISO)

Transplant Rejection (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

8-Br-cAMP (ISO)

[6]-Shogaol (ISO)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

ammonium chloride (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (EXP,ISO)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (EXP,ISO)

carbonyl sulfide (EXP)

chlordecone (ISO)

chlorpyrifos (EXP,ISO)

D-glucose (ISO)

diazinon (EXP)

dibutyl phthalate (EXP,ISO)

diethyl phthalate (EXP,ISO)

diisobutyl phthalate (EXP,ISO)

diisononyl phthalate (EXP,ISO)

disodium selenite (ISO)

doxorubicin (ISO)

ethanol (ISO)

fructose (ISO)

ginsenoside Rd (ISO)

ginsenoside Re (ISO)

glucose (ISO)

hydrogen peroxide (ISO)

lead diacetate (EXP)

maneb (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methimazole (EXP)

nicotine (EXP)

paracetamol (ISO)

paraquat (ISO)

parathion (EXP)

pioglitazone (ISO)

progesterone (EXP)

thimerosal (ISO)

titanium dioxide (ISO)

triclosan (ISO)

valproic acid (ISO)

XL147 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acetylcholine biosynthetic process (IBA,IEA,IMP,ISO,ISS)

biological_process (ND)

choline transport (IBA,IDA,IEA,ISO)

in utero embryonic development (ISO)

monoatomic ion transport (IEA)

neuromuscular synaptic transmission (IBA,ISO)

sodium ion transport (IEA)

synaptic transmission, cholinergic (IBA,ISO)

transmembrane transport (IEA)

Cellular Component

apical plasma membrane (IDA)

axon (IBA,IDA,IEA)

clathrin-coated endocytic vesicle (IDA)

cytoplasmic vesicle (IEA)

dendrite (IBA,IDA)

early endosome (IDA)

early endosome membrane (IEA,ISO,ISS)

membrane (IEA,ISO,NAS)

neuromuscular junction (ISO)

neuronal cell body (IEA,ISO)

perikaryon (IBA,IDA)

plasma membrane (IBA,IEA,ISO)

plasma membrane raft (IDA)

presynapse (IEA)

presynaptic membrane (IEA,ISO,ISS)

synapse (IBA)

synaptic vesicle (IDA)

synaptic vesicle membrane (IEA,ISO,ISS)

Molecular Function

choline binding (IEA,ISO)

choline transmembrane transporter activity (IDA,IEA,IMP,ISO)

choline:sodium symporter activity (IBA,ISO,ISS)

protein binding (IPI,ISO)

symporter activity (IEA)

transmembrane transporter activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

acetylcholine signaling pathway via muscarinic acetylcholine receptor (ISO)

acetylcholine signaling pathway via nicotinic acetylcholine receptor (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Regulation of the high-affinity choline transporter activity and trafficking by its association with cholesterol-rich lipid rafts.	Cuddy LK, etal., J Neurochem. 2014 Mar;128(5):725-40. doi: 10.1111/jnc.12490. Epub 2013 Nov 4.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Expression of the high-affinity choline transporter, CHT1, in the neuronal and non-neuronal cholinergic system of human and rat skin.	Haberberger RV, etal., J Invest Dermatol 2002 Oct;119(4):943-8.
5.	Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior.	Han S, etal., Sci Rep. 2017 Apr 18;7(1):900. doi: 10.1038/s41598-017-01088-6.
6.	Pivotal Advance: Up-regulation of acetylcholine synthesis and paracrine cholinergic signaling in intravascular transplant leukocytes during rejection of rat renal allografts.	Hecker A, etal., J Leukoc Biol. 2009 Jul;86(1):13-22. doi: 10.1189/jlb.1107722. Epub 2009 Apr 30.
7.	Ultrastructural localization of high-affinity choline transporter in the rat anteroventral thalamus and ventral tegmental area: differences in axon morphology and transporter distribution.	Holmstrand EC, etal., J Comp Neurol. 2010 Jun 1;518(11):1908-24. doi: 10.1002/cne.22310.
8.	Localisation of the high-affinity choline transporter-1 in the rat skeletal motor unit.	Lips KS, etal., Cell Tissue Res 2002 Mar;307(3):275-80. Epub 2002 Feb 14.
9.	Down-regulation of the non-neuronal acetylcholine synthesis and release machinery in acute allergic airway inflammation of rat and mouse.	Lips KS, etal., Life Sci. 2007 May 30;80(24-25):2263-9. Epub 2007 Jan 23.
10.	Expression of acetylcholine receptors by experimental rat renal allografts.	Meixner M, etal., Biomed Res Int. 2014;2014:289656. doi: 10.1155/2014/289656. Epub 2014 Jul 9.
11.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
12.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
13.	Identification and characterization of the high-affinity choline transporter.	Okuda T, etal., Nat Neurosci 2000 Feb;3(2):120-5.
14.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
15.	Expression of the high-affinity choline transporter CHT1 in epithelia.	Pfeil U, etal., Life Sci. 2003 Mar 28;72(18-19):2087-90.
16.	GOA pipeline	RGD automated data pipeline
17.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
19.	Comprehensive gene review and curation	RGD comprehensive gene curation
20.	Constitutive high-affinity choline transporter endocytosis is determined by a carboxyl-terminal tail dileucine motif.	Ribeiro FM, etal., J Neurochem. 2005 Jul;94(1):86-96.
21.	SEC14-like protein 1 interacts with cholinergic transporters.	Ribeiro FM, etal., Neurochem Int. 2007 Jan;50(2):356-64. Epub 2006 Nov 7.
22.	Acetyl-CoA the key factor for survival or death of cholinergic neurons in course of neurodegenerative diseases.	Szutowicz A, etal., Neurochem Res. 2013 Aug;38(8):1523-42. doi: 10.1007/s11064-013-1060-x. Epub 2013 May 16.

Additional References at PubMed

PMID:11027560	PMID:11068039	PMID:12237312	PMID:12654636	PMID:15173594	PMID:16162937	PMID:17196556	PMID:17548533	PMID:18088276	PMID:19405101	PMID:20510655	PMID:25041985
PMID:27569547	PMID:27996060	PMID:36808325

Genomics

Comparative Map Data

Slc5a7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	7,922,693 - 7,953,509 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	7,922,697 - 7,953,509 (-)	Ensembl				GRCr8
mRatBN7.2	9	7,595,440 - 7,626,258 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	7,595,444 - 7,626,258 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	10,642,717 - 10,673,490 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	14,881,214 - 14,911,984 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	13,632,603 - 13,663,363 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	5,294,377 - 5,330,822 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	5,294,381 - 5,330,815 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	4,342,128 - 4,379,724 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	9	133,838 - 165,943 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	9	3,418,007 - 3,448,801 (-)	NCBI		Celera
RGSC_v3.1	9	133,837 - 165,939 (+)	NCBI
Cytogenetic Map	9	q11	NCBI

SLC5A7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	107,986,524 - 108,013,994 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	107,986,523 - 108,013,994 (+)	Ensembl			hg38	GRCh38
GRCh37	2	108,602,980 - 108,630,450 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	107,969,427 - 107,996,876 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	108,061,512 - 108,088,957	NCBI
Celera	2	102,911,066 - 102,938,509 (+)	NCBI		Celera
Cytogenetic Map	2	q12.3	NCBI
HuRef	2	102,202,059 - 102,229,471 (+)	NCBI		HuRef
CHM1_1	2	108,606,867 - 108,634,740 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	108,448,101 - 108,475,570 (+)	NCBI		T2T-CHM13v2.0

Slc5a7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	54,580,618 - 54,606,071 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	54,580,618 - 54,606,062 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	54,273,590 - 54,299,038 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	54,273,590 - 54,299,034 (-)	Ensembl			mm10	GRCm38
MGSCv37	17	54,412,915 - 54,438,359 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	53,749,658 - 53,773,230 (-)	NCBI		MGSCv36	mm8
Celera	17	57,690,527 - 57,715,838 (-)	NCBI		Celera
Cytogenetic Map	17	C	NCBI
cM Map	17	28.23	NCBI

Slc5a7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955470	11,673,465 - 11,697,163 (+)	Ensembl
ChiLan1.0	NW_004955470	11,673,491 - 11,694,404 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC5A7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	19,921,057 - 19,948,593 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	19,923,825 - 19,951,361 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	93,917,086 - 93,944,308 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	109,018,073 - 109,045,292 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	109,017,805 - 109,046,860 (+)	Ensembl			panPan2	panpan1.1

SLC5A7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	35,879,880 - 35,908,203 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	35,883,245 - 35,908,569 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	35,802,105 - 35,829,230 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	36,734,146 - 36,761,272 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	36,737,513 - 36,762,849 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	36,467,972 - 36,495,096 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	36,749,953 - 36,777,069 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	36,938,435 - 36,965,586 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Slc5a7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	93,916,550 - 93,940,811 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936729	1,511,836 - 1,536,200 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936729	1,511,648 - 1,534,042 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC5A7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	47,996,335 - 48,022,379 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	47,994,116 - 48,020,744 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	50,164,607 - 50,190,998 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC5A7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	11,346,281 - 11,373,754 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	11,347,861 - 11,370,297 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	179,149,064 - 179,175,860 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc5a7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624749	11,347,609 - 11,371,330 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624749	11,347,602 - 11,371,113 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Slc5a7
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	91,367,428 - 91,391,451 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Slc5a7
139 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	916
Count of miRNA genes:	307
Interacting mature miRNAs:	400
Transcripts:	ENSRNOT00000014548
Prediction methods:	Microtar, Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303170	Bp332	Blood pressure QTL 332	3.73	0.027	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	6714888	84474983	Rat
631211	Bw4	Body weight QTL4	5.31		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	9	5346479	50346479	Rat
10054141	Gmadr4	Adrenal mass QTL 4	2.45	0.0074	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	9	1	21707400	Rat
7207814	Bmd91	Bone mineral density QTL 91	3.5		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	9	1	31250552	Rat
1578675	Bss17	Bone structure and strength QTL 17	3.8		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	9	3605355	21031556	Rat
9589055	Scfw5	Subcutaneous fat weight QTL 5	5.55	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	9	496645	45496645	Rat
1641911	Alcrsp13	Alcohol response QTL 13			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	6214995	51214995	Rat
1300124	Cm4	Cardiac mass QTL 4	3.55		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	9	1	41763315	Rat
61425	Cia15	Collagen induced arthritis QTL 15	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	9	5346479	50416711	Rat
631643	Bp120	Blood pressure QTL 120	3	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	6714888	29567695	Rat
9589158	Gluco65	Glucose level QTL 65	6.82	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	9	496645	45496645	Rat
7411592	Foco8	Food consumption QTL 8	7.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	496645	45496645	Rat
1298088	Edpm11	Estrogen-dependent pituitary mass QTL 11	2.5		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	6214995	51214995	Rat

Markers in Region

D9Got10

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	9	7,935,615 - 7,935,787 (+)	Marker Load Pipeline
mRatBN7.2	9	7,608,362 - 7,608,534 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	5,307,300 - 5,307,471	NCBI	Rnor6.0
Rnor_5.0	9	4,356,015 - 4,356,186	UniSTS	Rnor5.0
RGSC_v3.4	9	152,848 - 153,020	RGD	RGSC3.4
RGSC_v3.4	9	152,849 - 153,020	UniSTS	RGSC3.4
Celera	9	3,430,930 - 3,431,101	UniSTS
RGSC_v3.1	9	152,848 - 153,020	RGD
Cytogenetic Map	9	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
9	33	121	28	21	5	8	5	98	56	3	109	28	74	16	12	12

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053521	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006244251	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006244253	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB030947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474086	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000014548 ⟹ ENSRNOP00000014548

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	7,922,697 - 7,953,509 (-)	Ensembl
mRatBN7.2 Ensembl	9	7,595,444 - 7,626,258 (-)	Ensembl
Rnor_6.0 Ensembl	9	5,294,381 - 5,330,815 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000078055 ⟹ ENSRNOP00000068755

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	9	5,297,307 - 5,329,305 (-)	Ensembl

RefSeq Acc Id:

NM_053521 ⟹ NP_445973

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	7,922,693 - 7,953,509 (-)	NCBI
mRatBN7.2	9	7,595,440 - 7,626,258 (-)	NCBI
Rnor_6.0	9	5,294,377 - 5,330,822 (-)	NCBI
Rnor_5.0	9	4,342,128 - 4,379,724 (-)	NCBI
RGSC_v3.4	9	133,838 - 165,943 (+)	RGD
Celera	9	3,418,007 - 3,448,801 (-)	RGD

Sequence:

show sequence

CTTTTTTCCAATACCCGAATTGATTGATCGCCTCGCCCCACGGAGACCTCAGCGAGCTCCTTGT
CGGCACCCTCCACTCACCTCGCGCCTCCCTCCCTCGCTGTCCCACACAGCTCCGTACTGGGGGG
GACACCCGGACCCCTAAATCAGCTCCGGGTGACGCCAAGAAGATTTGATGAAGTAGCCCTCTGT
GGAAGGATCTTCACGGTACCCTAAATAAAAAATGCCTTTCCATGTAGAAGGACTAGTAGCGATT
ATCCTGTTCTACCTTCTTATATTTCTGGTTGGAATATGGGCTGCATGGAAAACCAAAAACAGCG
GTAATGCAGAAGAACGCAGCGAAGCCATCATAGTTGGGGGCCGAGACATTGGTTTGTTGGTTGG
TGGTTTTACCATGACAGCCACCTGGGTTGGAGGAGGTTACATCAACGGGACAGCTGAAGCAGTT
TATGGGCCAGGTTGTGGTCTAGCTTGGGCTCAGGCACCCATTGGATATTCTCTGAGTCTGATTT
TAGGTGGCCTGTTTTTTGCAAAACCTATGCGTTCCAAGGGATATGTGACTATGTTAGACCCGTT
TCAACAGATCTATGGAAAGCGCATGGGTGGGCTGCTGTTCATCCCTGCACTGATGGGAGAGATG
TTCTGGGCTGCAGCAATTTTCTCTGCATTAGGGGCTACCATCAGCGTAATCATTGATGTGGATG
TGAACATATCGGTCATTGTCTCCGCACTCATTGCCATTCTTTATACCCTCGTGGGAGGGCTCTA
CTCTGTGGCATATACTGATGTTGTACAGCTATTCTGCATTTTTATAGGATTGTGGATCAGTGTC
CCATTTGCCCTGTCACATCCTGCAGTCACCGACATTGGATTCACTGCTGTGCATGCTAAATACC
AGAGTCCCTGGCTGGGAACCATTGAATCAGTTGAAGTCTACACCTGGCTTGATAATTTTCTGTT
GTTGATGCTGGGTGGAATACCATGGCAAGCCTACTTCCAGAGGGTCCTCTCTTCATCGTCAGCG
ACCTATGCTCAGGTGCTGTCCTTCCTGGCAGCTTTTGGGTGCCTGGTGATGGCTCTACCAGCCA
TTTGCATTGGGGCCATTGGAGCCTCCACAGACTGGAACCAAACTGCATATGGGTTTCCAGATCC
CAAGACCAAGGAGGAAGCAGACATGATTCTCCCGATTGTTCTACAGTACCTCTGCCCTGTGTAC
ATTTCCTTCTTTGGGCTTGGTGCTGTTTCTGCTGCTGTCATGTCCTCGGCTGACTCATCCATCC
TATCAGCAAGTTCCATGTTTGCTCGGAATATCTACCAGCTTTCCTTCAGACAAAATGCATCAGA
CAAGGAAATTGTGTGGGTCATGAGGATCACTGTGTTTGTGTTTGGAGCATCTGCAACAGCCATG
GCCTTGCTCACGAAGACTGTGTATGGGCTCTGGTACCTGAGCTCTGACCTTGTCTACATCATCA
TCTTCCCACAGCTGCTCTGTGTACTCTTCATCAAAGGAACCAACACTTATGGGGCAGTTGCTGG
TTATATTTTTGGACTTTTCCTGAGAATTACCGGAGGAGAGCCATATCTATACTTGCAGCCCTTA
ATCTTCTACCCTGGTTATTACCCTGACAAGAATGGTATATACAATCAGAGGTTCCCATTTAAAA
CTCTCTCCATGGTTACCTCATTCTTTACCAACATTTGTGTTTCCTATCTAGCCAAGTATCTATT
TGAAAGTGGAACCTTGCCTCCAAAATTAGATATATTTGATGCTGTTGTCTCAAGGCACAGTGAA
GAGAACATGGACAAGACCATTCTAGTCAGAAATGAAAACATCAAATTAAATGAACTTGCACCTG
TAAAGCCTCGACAGAGCCTAACCCTCAGTTCAACTTTCACCAATAAAGAGGCTCTCCTTGATGT
TGATTCCAGTCCAGAGGGATCTGGGACTGAAGATAACTTACAATGACCCCATGTAAAATATACA
GAACAGGGCATTGCTGTAGGGTAATACTGGGAAAAAGGTTTGGAGCATATCTTATACATGTTAC
AATATAAATGTTTGAGGAAAAAAGTTTTTCAGAAATAAGATATTATGGATGAGTTCAGAAAAAT
AACAATTGCACAGTGAGGCAGAAGCAAGCGTGAAGGCAACAGCTTTATTTCTCATCGTAGCACT
TTTCATTTTGAATAGCTTTGTTAAGCACATAAAAATGCATAAAGCCCCAGCCAAAGAAAGTGGC
CAAATATTATTTATCTTTATTATGGAAGGAAGGAATATTTATTAAAAAGTCCATTGGAAGGAGA
TTGGATGGTCCCGATCATTTTCACTGGCGAATGCACTGGATAACAGATTAATTACTACAACATG
GAGGTTATGCATGTATTCACGGTCACTACTGTGAAGGATGCAGTGGGTTAGCCAGTACACTTTT
CCCCATGGGTAGGTTGTCTGGCTCTCCCATAATCTTAACTATGGCATTTACCCATTTTTCAAGG
TGTGCTTTCTTACCCTTTTTTGCCATCTAGCATGTGTACTCTCTCCATTCATCCCTCCATCTAT
CTATCCCTCCTTCTTTCTACACTCTCTCCTTTCTTCTGCTCTTTCCCTTTCACTCCCTTTCTCC
CTTCTCTTTATCTCTTTATATTTTGTTTCTGTGAGGGGCTGGAACTCTATTACAGGGCCTTGCA
CATGCTAAGTAAGAGCTCTCCTACTGAGCTACATTGCAACCTCACAATAATTTATTTTTTTAGT
AATATCGTACATTATTCTAAGCACAAGCAACACAACAATATCTTATTTAATAGTGACATTTTTA
TGTGAAAATGATAGAAAACAGAGTTTATGTTGGAGTAAGATAGAAGCACTGAGCCCTTTAAGTG
TGACCACAGTTGCTATATGCTCAAAGAGAAGGGTCCAAAACCAAGCATGAAATGGTTGTTGGGC
AGCATTACAGCAATAAGTCAAGAAGAAAAGGAAAAGAAGGAGAAGAAGAAAAACGGATTTCTGT
CTCCAGCTTTTATACATTAAATGTTGTTACACATTATAAATATAATGTCTTGGCTTATCTTCTA
AGAGTATTGGAGGCAAAGTTGAGCCATATATAAAGTGTGGTTTCTGTCTAACATCTGTTACAAG
TGCCACCTGCTTCATCAGCATGCATTCGACGCATATATATTACCAGCAGTTCCCAAATAACTCT
CTGAGAAACTGGGAAACAAACCCTGCTTACTTTTGGACATCCAATAATGTAAGAGTTTAGTGCT
AAGGATCTACTCTTGACACTTTTCCACATAAGCCATTTTTAGGGACTGGACAGATCACCACAAG
TGTGTATATTGATTTTCAAATGTAATAGAAAACAAAAAGTAAAAACAAGTCATAGAAGAAGCCA
TCATTTTTAATGTCTTTTGTGTACATGGATTTCAGGAGGTCAATCATTAAATGTAATTTTGCTT
TTCTTTGTAGCATTCAGAATTACATATAAAACTTGTGCCACCAAACCCTAGAATTCTTTTTATA
AGTTACAGTTATTATCTCTTAAAGCATCACATTTGGAACTCCTTTCTTTAAAAAGGATGACTTA
AAAATTCCTACTGTGACTTTTAAAATGTAAAATTAAATAATTTTACATATTGTAATGTCCTATT
TTTCAGGATTGTCTCAATCCTTAAACCACTTTACTGATTTGTGTATGTACGTAAGGAAGAGAAT
TCATTTACCCTCCAGTTTATCTCAGAATCAGCTCACTAGCTATGGAGTAGTTATGGAAATTATG
GAGTCTGAGATGTTCAAACATGGTGTGAGAAAAGAGTCAAAGGAAAAAAGAAAACACAGATAAA
AAAGTAGTAAACTTTGTACTTGAAAATCTACTAGTGACAATGAAATTTCTGGTAAACATGGTAT
TTCAGATGCACAAAGTCTTCCAACAGAGACAAAAGAGAAACTTTTGCCCAACTCATGATCTTCC
ATGAAATTGTTGAGGTGTTTGCTTGCATTAGGAACATCACAGAACCTCACTCACACTAGATCTC
ACAGCGAAGCAGGTTCCTTTCACAGACATTACACTTTGTAATGCTCTTAGTCAACAACTGTCCA
ACTAAGCTTAAAATATTTAAAGTATCATAATAGCAAAAATGAGAGAAGAATCCCAAGATATTTA
TTTATGCATACTCTTGAATGGAATTCCCCATGATTTCCAAGAAAGAGATGATGCTTCAAGGTAT
ATTGGATTGGAGACATCTCTAAATTATTCCAGATTCAAGCAGCAGACCTCATTTTCAAATCCCC
AATGAAATCAAAATAACCCAAATGTTTCAGCCTCTTGCTTGGGAAGTAATACATGTGGATAGCA
TTTGAGCAAGATAGGAGTTTCACTCCTATATATTAACAATGATTGTGCTATGTTTCTTAGGTAA
TTTGTGTTCCTCTCCATGTGTTCAGAACATCAAGCTTGTAGCTGGAACGATATGTTAACAAGCT
GTCAAATGCTCAGTGCCAAAATCCAATTTCATTGTTATACTTACAAGTAATGAATTTTATGTGC
ATATTATATGAATGTAAGCTTGAAATGAATGCATTTAATATTTAATATAATGTATATTGAAAAT
GTCATTTGTAAATAATGAATTAGCATTATATTTTAAACATAAATCATCATTTCCCTTTTTGTCC
TTCTACAAAATTTGCTCTGGTATCCTATGTAACGTATAATAAGTTTGTTATAATGTATGTTGGC
TACTGCATAGACAAATGCATAGAATTGTTCCAAAACTTATATTTTTATCTGTCAAAATGTTATA
CAAAATTATACAGAAATAAGTAGATTTACAAGTACACATGTATGTGTTCAAATGTAATGATACT
GTATTAAATTATTCCATTGCAATTCAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_445973	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAA90484	(Get FASTA)	NCBI Sequence Viewer
	EDL83229	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000014548
GenBank Protein	Q9JMD7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_445973 ⟸ NM_053521

- UniProtKB:

Q9JMD7 (UniProtKB/Swiss-Prot), G3V7G1 (UniProtKB/TrEMBL), A6KQA3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPFHVEGLVAIILFYLLIFLVGIWAAWKTKNSGNAEERSEAIIVGGRDIGLLVGGFTMTATWVG
GGYINGTAEAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGG
LLFIPALMGEMFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGGLYSVAYTDVVQL
FCIFIGLWISVPFALSHPAVTDIGFTAVHAKYQSPWLGTIESVEVYTWLDNFLLLMLGGIPWQA
YFQRVLSSSSATYAQVLSFLAAFGCLVMALPAICIGAIGASTDWNQTAYGFPDPKTKEEADMIL
PIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRIT
VFVFGASATAMALLTKTVYGLWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLFLRIT
GGEPYLYLQPLIFYPGYYPDKNGIYNQRFPFKTLSMVTSFFTNICVSYLAKYLFESGTLPPKLD
IFDAVVSRHSEENMDKTILVRNENIKLNELAPVKPRQSLTLSSTFTNKEALLDVDSSPEGSGTE
DNLQ

hide sequence

Ensembl Acc Id:

ENSRNOP00000014548 ⟸ ENSRNOT00000014548

Ensembl Acc Id:

ENSRNOP00000068755 ⟸ ENSRNOT00000078055

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9JMD7-F1-model_v2	AlphaFold	Q9JMD7	1-580	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:69270	AgrOrtholog
BioCyc Gene	G2FUF-28381	BioCyc
Ensembl Genes	ENSRNOG00000010597	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000014548	ENTREZGENE
Gene3D-CATH	1.20.1730.10	UniProtKB/Swiss-Prot
InterPro	Choline_transporter	UniProtKB/Swiss-Prot
	Na/Glc_symporter_sf	UniProtKB/Swiss-Prot
	Na/solute_symporter	UniProtKB/Swiss-Prot
KEGG Report	rno:85426	UniProtKB/Swiss-Prot
NCBI Gene	85426	ENTREZGENE
PANTHER	HIGH AFFINITY CHOLINE TRANSPORTER 1	UniProtKB/Swiss-Prot
	HIGH-AFFINITY CHOLINE TRANSPORTER 1	UniProtKB/Swiss-Prot
Pfam	SSF	UniProtKB/Swiss-Prot
PhenoGen	Slc5a7	PhenoGen
PROSITE	NA_SOLUT_SYMP_3	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000010597	RatGTEx
UniProt	A6KQA3	ENTREZGENE, UniProtKB/TrEMBL
	G3V7G1	ENTREZGENE, UniProtKB/TrEMBL
	Q9JMD7	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-09	Slc5a7	solute carrier family 5 member 7	Slc5a7	solute carrier family 5 (sodium/choline cotransporter), member 7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-08-02	Slc5a7	solute carrier family 5 (sodium/choline cotransporter), member 7	Slc5a7	solute carrier family 5 (choline transporter), member 7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Slc5a7	solute carrier family 5 (choline transporter), member 7		solute carrier family 5, member 7	Name updated	1299863	APPROVED
2002-06-10	Slc5a7	solute carrier family 5, member 7			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in the nerve fibres in the rat skin	634187
gene_process	involved in the skin's neuronal and non-neuronal cholinergic system	634187
gene_regulation	regulation is Na+-dependent and is blocked by hemicholinium-3	634187

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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RGD Manual Annotations