Cd82 (Cd82 molecule) - Rat Genome Database

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Gene: Cd82 (Cd82 molecule) Rattus norvegicus
Analyze
Symbol: Cd82
Name: Cd82 molecule
RGD ID: 69070
Description: Predicted to be located in membrane. Predicted to be active in plasma membrane. Biomarker of hypertension and ovarian cancer. Orthologous to human CD82 (CD82 molecule); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CD82 antigen; CD82 antigen (R2 leukocyte antigen antigen detected by monoclonal and antibody IA4)); CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)); Kai1; kangai 1; Kangai 1 (suppression of tumerigenicity 6 prostate) CD82 antigen; Kangai 1 (suppression of tumerigenicity 6, prostate) CD82 antigen; kangai 1 (suppression of tumorigenicity 6) prostate; kangai 1 (suppression of tumorigenicity 6), prostate; Kangai 1 (suppression of tumorigenicity 6, prostate, CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)); metastasis suppressor Kangai-1 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8399,842,748 - 99,887,298 (-)NCBIGRCr8
mRatBN7.2379,387,361 - 79,431,847 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl379,385,887 - 79,431,809 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx382,861,325 - 82,905,239 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0391,460,386 - 91,504,299 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0389,311,775 - 89,356,142 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0382,324,344 - 82,368,846 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl382,324,354 - 82,368,357 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0389,026,114 - 89,070,616 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4377,831,771 - 77,875,764 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1377,728,200 - 77,772,102 (-)NCBI
Celera378,589,536 - 78,633,414 (-)NCBICelera
Cytogenetic Map3q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 15 of 15 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd82Ratbreast carcinoma  ISOCD82 (Homo sapiens)2289398protein:decreased expression:breastRGD 
Cd82Ratcervical squamous cell carcinoma  ISOCD82 (Homo sapiens)2289399protein:decreased expression:uterine cervixRGD 
Cd82Ratendometrial carcinoma disease_progressionISOCD82 (Homo sapiens)2289403 RGD 
Cd82RatGliosis  IEP 2289406mRNA:increased expression:retinaRGD 
Cd82Rathypertension  IEP 2289422mRNA:increased expression:thymusRGD 
Cd82RatNeoplasm Metastasis  IEP 2289407associated with Carcinoma more ...RGD 
Cd82RatNeoplasm Metastasis  ISOCD82 (Homo sapiens)2289402associated with Prostatic Neoplasms and mRNA:decreased expression:boneRGD 
Cd82RatNeoplasm Metastasis  IEP 68869associated with Prostatic Neoplasms and mRNA:decreased expressionRGD 
Cd82RatNeoplasm Metastasis  ISOCD82 (Homo sapiens)2289400associated with Carcinoma more ...RGD 
Cd82RatNeoplasm Metastasis  ISOCD82 (Homo sapiens)2289425associated with Prostatic Neoplasms and DNA:loss of heterozygosityRGD 
Cd82Ratovarian cancer disease_progressionIEP 2289405protein:altered localization and decreased expression:ovaryRGD 
Cd82Ratprostate cancer disease_progressionISOCD82 (Homo sapiens)2289404protein:decreased expression:prostate glandRGD 
Cd82Rattransitional cell carcinoma  ISOCD82 (Homo sapiens)2289390 RGD 
Cd82Raturinary bladder cancer  ISOCD82 (Homo sapiens)2289391 RGD 
Cd82Raturinary bladder cancer disease_progressionISOCD82 (Homo sapiens)2289401protein:decreased expression:urinary bladderRGD 
1 to 15 of 15 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd82Ratintellectual disability  ISOCD82 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd82RatNeoplasm Invasiveness  ISOCD82 (Homo sapiens)11554173CTD Direct Evidence: therapeuticCTDPMID:20075392
Cd82RatNeoplasm Metastasis  ISOCD82 (Homo sapiens)11554173CTD Direct Evidence: therapeuticCTDPMID:20075392
Cd82RatSpontaneous Abortions  ISOCD82 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:20075392

1 to 20 of 114 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd82Rat1,2,4-trimethylbenzene decreases expressionEXP 6480464pseudocumene results in decreased expression of CD82 proteinCTDPMID:17337753
Cd82Rat1,2-dichloroethane decreases expressionISOCd82 (Mus musculus)6480464ethylene dichloride results in decreased expression of CD82 mRNACTDPMID:28960355
Cd82Rat17beta-estradiol multiple interactionsISOCD82 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in decreased expression of CD82 mRNA and Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of CD82 protein]CTDPMID:21685244 and PMID:30165855
Cd82Rat17beta-estradiol increases expressionISOCd82 (Mus musculus)6480464Estradiol results in increased expression of CD82 mRNACTDPMID:39298647
Cd82Rat17beta-estradiol decreases expressionISOCD82 (Homo sapiens)6480464Estradiol results in decreased expression of CD82 proteinCTDPMID:21685244
Cd82Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOCd82 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of CD82 mRNACTDPMID:21570461
Cd82Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOCd82 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of CD82 mRNACTDPMID:33956508
Cd82Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of CD82 mRNACTDPMID:32109520 and PMID:34747641
Cd82Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOCD82 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of CD82 proteinCTDPMID:21685244
Cd82Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOCD82 (Homo sapiens)6480464Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of CD82 protein]CTDPMID:21685244
Cd82Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of CD82 mRNACTDPMID:21346803
Cd82Rat2,6-dimethoxyphenol multiple interactionsISOCD82 (Homo sapiens)6480464[Furaldehyde co-treated with pyrogallol 1 more ...CTDPMID:38598786
Cd82Rat2-palmitoylglycerol increases expressionISOCD82 (Homo sapiens)64804642-palmitoylglycerol results in increased expression of CD82 mRNACTDPMID:37199045
Cd82Rat3,4-methylenedioxymethamphetamine increases expressionISOCd82 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of CD82 mRNACTDPMID:20188158
Cd82Rat4,4'-sulfonyldiphenol increases expressionISOCd82 (Mus musculus)6480464bisphenol S results in increased expression of CD82 mRNACTDPMID:30951980
Cd82Rat4,4'-sulfonyldiphenol decreases expressionISOCd82 (Mus musculus)6480464bisphenol S results in decreased expression of CD82 mRNACTDPMID:39298647
Cd82Rat4-hydroxyphenyl retinamide increases expressionISOCd82 (Mus musculus)6480464Fenretinide results in increased expression of CD82 mRNACTDPMID:28973697
Cd82Rat4-nitrophenol increases expressionISOCd82 (Mus musculus)64804644-nitrophenol results in increased expression of CD82 mRNACTDPMID:34673133
Cd82Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of CD82 mRNACTDPMID:30047161
Cd82Ratacrylamide decreases expressionISOCD82 (Homo sapiens)6480464Acrylamide results in decreased expression of CD82 mRNACTDPMID:32763439

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Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd82Ratbiological_process  ND 15984072/2008: no relevant rat dataRGD 

Cellular Component
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd82Ratmembrane located_inIEAInterPro:IPR000301 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Cd82Ratmembrane located_inIEAInterPro:IPR008952 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Cd82Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Cd82Ratmembrane located_inIEAUniRule:UR0000494081600115GO_REF:0000104UniProtGO_REF:0000104
Cd82Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Cd82Ratplasma membrane is_active_inIBAFB:FBgn0024361 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cd82Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
Cd82Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Cd82Ratplasma membrane located_inISOCD82 (Homo sapiens)1624291 PMID:30463011RGDPMID:30463011
Cd82Ratplasma membrane located_inIEAUniProtKB:P27701 and ensembl:ENSP000002271551600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 10 of 10 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd82Ratprotein binding enablesISOCD82 (Homo sapiens)1624291UniProtKB:O15552 more ...RGDPMID:15205336 more ...

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cd82Ratp53 signaling pathway   IEA 6907045 KEGGrno:04115

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#
Reference Title
Reference Citation
1. Expression of KAI1/CD82 and MRP-1/CD9 in transitional cell carcinoma of bladder. Ai X, etal., J Huazhong Univ Sci Technolog Med Sci. 2007 Feb;27(1):79-82.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Frequent loss of KAI1 expression in squamous and lymphoid neoplasms. An immunohistochemical study of archival tissues. Geradts J, etal., Am J Pathol 1999 Jun;154(6):1665-71.
4. Loss of expression and altered localization of KAI1 and CD9 protein are associated with epithelial ovarian cancer progression. Houle CD, etal., Gynecol Oncol. 2002 Jul;86(1):69-78.
5. Aberrant expression of novel and previously described cell membrane markers in human breast cancer cell lines and tumors. Huang H, etal., Clin Cancer Res. 2005 Jun 15;11(12):4357-64.
6. Downregulation of KAI1 mRNA in localised prostate cancer and its bony metastases does not correlate with p53 overexpression. Jackson P, etal., Prostate Cancer Prostatic Dis. 2003;6(2):174-81.
7. Location of KAI1 on the short arm of human chromosome 11 and frequency of allelic loss in advanced human prostate cancer. Kawana Y, etal., Prostate. 1997 Aug 1;32(3):205-13.
8. KAI1 metastasis suppressor protein is down-regulated during the progression of human endometrial cancer. Liu FS, etal., Clin Cancer Res. 2003 Apr;9(4):1393-8.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. Establishment of rat hepatocellular carcinoma cell lines with differing metastatic potential in nude mice. Ogawa K, etal., Int J Cancer. 2001 Mar 15;91(6):797-802.
12. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
13. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
14. GOA pipeline RGD automated data pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Comprehensive gene review and curation RGD comprehensive gene curation
18. Protein networking in bladder cancer: immunoreactivity for FGFR3, EGFR, ERBB2, KAI1, PTEN, and RAS in normal and malignant urothelium. Rotterud R, etal., Histol Histopathol. 2007 Apr;22(4):349-63.
19. Reduced metastasis-suppressor gene mRNA-expression in breast cancer brain metastases. Stark AM, etal., J Cancer Res Clin Oncol. 2005 Mar;131(3):191-8. Epub 2004 Dec 8.
20. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
1 to 20 of 28 rows
PMID:19199708   PMID:19741124   PMID:20458337   PMID:30463011  



Cd82
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8399,842,748 - 99,887,298 (-)NCBIGRCr8
mRatBN7.2379,387,361 - 79,431,847 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl379,385,887 - 79,431,809 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx382,861,325 - 82,905,239 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0391,460,386 - 91,504,299 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0389,311,775 - 89,356,142 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0382,324,344 - 82,368,846 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl382,324,354 - 82,368,357 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0389,026,114 - 89,070,616 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4377,831,771 - 77,875,764 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1377,728,200 - 77,772,102 (-)NCBI
Celera378,589,536 - 78,633,414 (-)NCBICelera
Cytogenetic Map3q31NCBI
CD82
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381144,564,409 - 44,620,358 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1144,564,427 - 44,620,363 (+)EnsemblGRCh38hg38GRCh38
GRCh371144,587,213 - 44,641,908 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361144,543,717 - 44,597,915 (+)NCBINCBI36Build 36hg18NCBI36
Celera1144,734,291 - 44,788,479 (+)NCBICelera
Cytogenetic Map11p11.2NCBI
HuRef1144,296,423 - 44,350,592 (+)NCBIHuRef
CHM1_11144,585,957 - 44,640,111 (+)NCBICHM1_1
T2T-CHM13v2.01144,720,425 - 44,776,379 (+)NCBIT2T-CHM13v2.0
Cd82
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39293,249,447 - 93,293,295 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl293,249,456 - 93,293,485 (-)EnsemblGRCm39 Ensembl
GRCm38293,419,102 - 93,462,950 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl293,419,111 - 93,463,140 (-)EnsemblGRCm38mm10GRCm38
MGSCv37293,259,269 - 93,303,103 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36293,219,951 - 93,263,335 (-)NCBIMGSCv36mm8
Celera294,814,780 - 94,859,821 (-)NCBICelera
Cytogenetic Map2E1NCBI
cM Map251.62NCBI
Cd82
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554223,033,133 - 3,052,153 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554223,035,887 - 3,069,298 (-)NCBIChiLan1.0ChiLan1.0
CD82
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2946,780,583 - 46,836,160 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11146,786,918 - 46,842,472 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01144,526,010 - 44,581,560 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11145,020,362 - 45,075,876 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1145,020,319 - 45,075,876 (+)Ensemblpanpan1.1panPan2
CD82
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11844,658,414 - 44,707,897 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1844,659,180 - 44,706,768 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.01845,317,202 - 45,369,506 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1845,317,220 - 45,368,392 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11844,800,179 - 44,851,496 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01844,353,829 - 44,406,031 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01845,086,983 - 45,139,553 (-)NCBIUU_Cfam_GSD_1.0
Cd82
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494721,960,790 - 21,973,529 (-)NCBIHiC_Itri_2
CD82
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl217,750,660 - 17,803,126 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1217,751,153 - 17,803,172 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2219,249,749 - 19,264,391 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CD82
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1120,736,216 - 20,793,943 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl120,735,287 - 20,763,160 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038117,969,772 - 118,024,761 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd82
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247673,556,128 - 3,589,956 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Cd82
212 total Variants

Predicted Target Of
Summary Value
Count of predictions:393
Count of miRNA genes:215
Interacting mature miRNAs:252
Transcripts:ENSRNOT00000000052
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 38 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat

1 to 10 of 38 rows
RH127894  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2379,387,524 - 79,387,715 (+)MAPPERmRatBN7.2
Rnor_6.0382,324,509 - 82,324,699NCBIRnor6.0
Rnor_5.0389,026,279 - 89,026,469UniSTSRnor5.0
RGSC_v3.4377,831,931 - 77,832,121UniSTSRGSC3.4
Celera378,589,696 - 78,589,886UniSTS
RH 3.4 Map3685.5UniSTS
Cytogenetic Map3q24UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000000052   ⟹   ENSRNOP00000000052
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl379,387,361 - 79,431,782 (-)Ensembl
Rnor_6.0 Ensembl382,324,354 - 82,368,357 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097921   ⟹   ENSRNOP00000078723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl379,387,367 - 79,431,310 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100406   ⟹   ENSRNOP00000084636
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl379,387,367 - 79,431,311 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119233   ⟹   ENSRNOP00000091451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl379,385,887 - 79,431,809 (-)Ensembl
RefSeq Acc Id: NM_031797   ⟹   NP_113985
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,842,752 - 99,886,744 (-)NCBI
mRatBN7.2379,387,365 - 79,431,358 (-)NCBI
Rnor_6.0382,324,349 - 82,368,357 (-)NCBI
Rnor_5.0389,026,114 - 89,070,616 (-)NCBI
RGSC_v3.4377,831,771 - 77,875,764 (-)RGD
Celera378,589,536 - 78,633,414 (-)RGD
Sequence:
RefSeq Acc Id: XM_006234597   ⟹   XP_006234659
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,842,748 - 99,887,208 (-)NCBI
mRatBN7.2379,387,370 - 79,431,805 (-)NCBI
Rnor_6.0382,324,344 - 82,368,794 (-)NCBI
Rnor_5.0389,026,114 - 89,070,616 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006234598   ⟹   XP_006234660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,842,748 - 99,887,298 (-)NCBI
mRatBN7.2379,387,370 - 79,431,847 (-)NCBI
Rnor_6.0382,324,344 - 82,368,846 (-)NCBI
Rnor_5.0389,026,114 - 89,070,616 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105948   ⟹   XP_038961876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,842,748 - 99,861,087 (-)NCBI
mRatBN7.2379,387,370 - 79,405,697 (-)NCBI
RefSeq Acc Id: XM_039105951   ⟹   XP_038961879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,842,748 - 99,850,372 (-)NCBI
mRatBN7.2379,387,361 - 79,394,473 (-)NCBI
RefSeq Acc Id: XM_039105953   ⟹   XP_038961881
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,842,748 - 99,849,601 (-)NCBI
mRatBN7.2379,387,361 - 79,394,209 (-)NCBI
1 to 5 of 10 rows
1 to 5 of 10 rows
RefSeq Acc Id: NP_113985   ⟸   NM_031797
- UniProtKB: O70352 (UniProtKB/Swiss-Prot),   Q6IN14 (UniProtKB/TrEMBL),   A6HNI9 (UniProtKB/TrEMBL),   F7EV99 (UniProtKB/TrEMBL),   A0A8I5ZZR7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234660   ⟸   XM_006234598
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006234659   ⟸   XM_006234597
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000000052   ⟸   ENSRNOT00000000052
RefSeq Acc Id: XP_038961879   ⟸   XM_039105951
- Peptide Label: isoform X3

Name Modeler Protein Id AA Range Protein Structure
AF-O70352-F1-model_v2 AlphaFold O70352 1-266 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13692232
Promoter ID:EPDNEW_R2756
Type:initiation region
Name:Cd82_1
Description:Cd82 molecule
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0382,368,340 - 82,368,400EPDNEW


1 to 31 of 31 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-48668 BioCyc
Ensembl Genes ENSRNOG00000000047 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000000052 ENTREZGENE
  ENSRNOT00000097921 ENTREZGENE
Gene3D-CATH 1.10.1450.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7096826 IMAGE-MGC_LOAD
InterPro Tetraspanin UniProtKB/Swiss-Prot
  Tetraspanin/Peripherin UniProtKB/Swiss-Prot
  Tetraspanin_CS UniProtKB/Swiss-Prot
  Tetraspanin_EC2_sf UniProtKB/Swiss-Prot
MGC_CLONE MGC:91618 IMAGE-MGC_LOAD
NCBI Gene 83628 ENTREZGENE
PANTHER CD82 ANTIGEN UniProtKB/Swiss-Prot
  PTHR19282 UniProtKB/Swiss-Prot
Pfam Tetraspanin UniProtKB/Swiss-Prot
PhenoGen Cd82 PhenoGen
PIRSF Tetraspanin UniProtKB/Swiss-Prot
PRINTS TMFOUR UniProtKB/Swiss-Prot
PROSITE TM4_1 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000000047 RatGTEx
Superfamily-SCOP SSF48652 UniProtKB/Swiss-Prot
TIGR TC229731
UniProt A0A8I5ZP15_RAT UniProtKB/TrEMBL
  A0A8I5ZZR7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJM9_RAT UniProtKB/TrEMBL
  A6HNI9 ENTREZGENE, UniProtKB/TrEMBL
  A6HNJ0 ENTREZGENE, UniProtKB/TrEMBL
  CD82_RAT UniProtKB/Swiss-Prot
  F7EV99 ENTREZGENE, UniProtKB/TrEMBL
  O70352 ENTREZGENE
  Q6IN14 ENTREZGENE
1 to 31 of 31 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-29 Cd82  Cd82 molecule  Cd82  CD82 antigen  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Cd82  CD82 antigen  Kai1  kangai 1  Symbol and Name updated 1299863 APPROVED
2004-12-14 Kai1  kangai 1      Symbol and Name status set to approved 1299863 APPROVED
2002-06-10 Kai1  kangai 1      Name updated 70585 PROVISIONAL

Note Type Note Reference
gene_disease down-regulated in squamous cell carcinomas 68869
gene_disease down-regulated in squamous cell carcinomas 70284
gene_disease 2.0-kb mRNA is associated with high metastatic ability by prostate cancer cells; 1.8-kb transcript is upregulated but not associated with metastasis 68869
gene_disease 2.0-kb mRNA is associated with high metastatic ability by prostate cancer cells; 1.8-kb transcript is upregulated but not associated with metastasis 70284
gene_disease expression not found in some low-grade and high-grade lymphomas 68869
gene_disease expression not found in some low-grade and high-grade lymphomas 70284
gene_expression expressed in squamous cell carcinomas 68869
gene_expression expressed in squamous cell carcinomas 70284
gene_process suppresses the metastatic potential of prostate cancer cells 68869
gene_process suppresses the metastatic potential of prostate cancer cells 70284
gene_product glycoprotein that belongs to the transmembrane 4 superfamily (TM4SF) 68869
gene_product glycoprotein that belongs to the transmembrane 4 superfamily (TM4SF) 70284
gene_transcript expresses a predominant 2.0-kb and a minor 1.8-kb-sized RNA 70284