Cd82 (Cd82 molecule) - Rat Genome Database

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Gene: Cd82 (Cd82 molecule) Rattus norvegicus
Analyze
Symbol: Cd82
Name: Cd82 molecule
RGD ID: 69070
Description: Predicted to be located in membrane. Predicted to be active in plasma membrane. Biomarker of hypertension and ovarian cancer. Orthologous to human CD82 (CD82 molecule); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CD82 antigen; CD82 antigen (R2 leukocyte antigen antigen detected by monoclonal and antibody IA4)); CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)); Kai1; kangai 1; Kangai 1 (suppression of tumerigenicity 6 prostate) CD82 antigen; Kangai 1 (suppression of tumerigenicity 6, prostate) CD82 antigen; kangai 1 (suppression of tumorigenicity 6) prostate; kangai 1 (suppression of tumorigenicity 6), prostate; Kangai 1 (suppression of tumorigenicity 6, prostate, CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)); metastasis suppressor Kangai-1 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8399,842,748 - 99,887,298 (-)NCBIGRCr8
mRatBN7.2379,387,361 - 79,431,847 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl379,385,887 - 79,431,809 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx382,861,325 - 82,905,239 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0391,460,386 - 91,504,299 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0389,311,775 - 89,356,142 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0382,324,344 - 82,368,846 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl382,324,354 - 82,368,357 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0389,026,114 - 89,070,616 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4377,831,771 - 77,875,764 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1377,728,200 - 77,772,102 (-)NCBI
Celera378,589,536 - 78,633,414 (-)NCBICelera
Cytogenetic Map3q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trimethylbenzene  (EXP)
1,2-dichloroethane  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nitrophenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
actinomycin D  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
butanal  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
Cuprizon  (EXP)
dibutyl phthalate  (ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
fenthion  (ISO)
flutamide  (EXP)
formaldehyde  (ISO)
genistein  (ISO)
L-ascorbic acid  (EXP)
lead(0)  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methidathion  (ISO)
methylmercury chloride  (ISO)
nefazodone  (EXP)
nickel sulfate  (ISO)
nimesulide  (EXP)
Nutlin-3  (ISO)
oxaliplatin  (EXP)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP)
pentachlorophenol  (ISO)
pentanal  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
phenethyl isothiocyanate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propanal  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sotorasib  (ISO)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
temozolomide  (ISO)
Terfenadine  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
topotecan  (EXP)
trametinib  (ISO)
triphenyl phosphate  (ISO)
undecane  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Expression of KAI1/CD82 and MRP-1/CD9 in transitional cell carcinoma of bladder. Ai X, etal., J Huazhong Univ Sci Technolog Med Sci. 2007 Feb;27(1):79-82.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Frequent loss of KAI1 expression in squamous and lymphoid neoplasms. An immunohistochemical study of archival tissues. Geradts J, etal., Am J Pathol 1999 Jun;154(6):1665-71.
4. Loss of expression and altered localization of KAI1 and CD9 protein are associated with epithelial ovarian cancer progression. Houle CD, etal., Gynecol Oncol. 2002 Jul;86(1):69-78.
5. Aberrant expression of novel and previously described cell membrane markers in human breast cancer cell lines and tumors. Huang H, etal., Clin Cancer Res. 2005 Jun 15;11(12):4357-64.
6. Downregulation of KAI1 mRNA in localised prostate cancer and its bony metastases does not correlate with p53 overexpression. Jackson P, etal., Prostate Cancer Prostatic Dis. 2003;6(2):174-81.
7. Location of KAI1 on the short arm of human chromosome 11 and frequency of allelic loss in advanced human prostate cancer. Kawana Y, etal., Prostate. 1997 Aug 1;32(3):205-13.
8. KAI1 metastasis suppressor protein is down-regulated during the progression of human endometrial cancer. Liu FS, etal., Clin Cancer Res. 2003 Apr;9(4):1393-8.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. Establishment of rat hepatocellular carcinoma cell lines with differing metastatic potential in nude mice. Ogawa K, etal., Int J Cancer. 2001 Mar 15;91(6):797-802.
12. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
13. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
14. GOA pipeline RGD automated data pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Comprehensive gene review and curation RGD comprehensive gene curation
18. Protein networking in bladder cancer: immunoreactivity for FGFR3, EGFR, ERBB2, KAI1, PTEN, and RAS in normal and malignant urothelium. Rotterud R, etal., Histol Histopathol. 2007 Apr;22(4):349-63.
19. Reduced metastasis-suppressor gene mRNA-expression in breast cancer brain metastases. Stark AM, etal., J Cancer Res Clin Oncol. 2005 Mar;131(3):191-8. Epub 2004 Dec 8.
20. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
21. Decreased expression of KAI1 metastasis suppressor gene is a recurrence predictor in primary pTa and pT1 urothelial bladder carcinoma. Su JS, etal., Int J Urol. 2004 Feb;11(2):74-82.
22. Identification of the rat homologue of KAI1 and its expression in Dunning rat prostate cancers. Suzuki H, etal., Prostate 1998 Dec 1;37(4):253-60.
23. Localization of 54 rat genes, and definition of new synteny groups conserved in the human and the rat. Szpirer C, etal., Mamm Genome 2000 Sep;11(9):729-35
24. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
25. KAI1 expression can be a predictor of stage A prostate cancer progression. Tozawa K, etal., Prostate Cancer Prostatic Dis. 2001;4(3):150-153.
26. Temporal changes in gene expression after injury in the rat retina. Vazquez-Chona F, etal., Invest Ophthalmol Vis Sci. 2004 Aug;45(8):2737-46.
27. [Expression of metastasis suppressor gene KAI1/CD82 in cervical squamous cell carcinoma and its clinical significance.] Xiong Y, etal., Ai Zheng. 2005 Jan;24(1):110-5.
28. Identification of upregulated genes in the thymus of spontaneously hypertensive rats by cDNA representational difference analysis. Zhao XS, etal., Blood Press. 1998 Nov;7(5-6):316-23.
Additional References at PubMed
PMID:19199708   PMID:19741124   PMID:20458337   PMID:30463011  


Genomics

Comparative Map Data
Cd82
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8399,842,748 - 99,887,298 (-)NCBIGRCr8
mRatBN7.2379,387,361 - 79,431,847 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl379,385,887 - 79,431,809 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx382,861,325 - 82,905,239 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0391,460,386 - 91,504,299 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0389,311,775 - 89,356,142 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0382,324,344 - 82,368,846 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl382,324,354 - 82,368,357 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0389,026,114 - 89,070,616 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4377,831,771 - 77,875,764 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1377,728,200 - 77,772,102 (-)NCBI
Celera378,589,536 - 78,633,414 (-)NCBICelera
Cytogenetic Map3q31NCBI
CD82
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381144,564,409 - 44,620,358 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1144,564,427 - 44,620,363 (+)EnsemblGRCh38hg38GRCh38
GRCh371144,587,213 - 44,641,908 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361144,543,717 - 44,597,915 (+)NCBINCBI36Build 36hg18NCBI36
Celera1144,734,291 - 44,788,479 (+)NCBICelera
Cytogenetic Map11p11.2NCBI
HuRef1144,296,423 - 44,350,592 (+)NCBIHuRef
CHM1_11144,585,957 - 44,640,111 (+)NCBICHM1_1
T2T-CHM13v2.01144,720,425 - 44,776,379 (+)NCBIT2T-CHM13v2.0
Cd82
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39293,249,447 - 93,293,295 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl293,249,456 - 93,293,485 (-)EnsemblGRCm39 Ensembl
GRCm38293,419,102 - 93,462,950 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl293,419,111 - 93,463,140 (-)EnsemblGRCm38mm10GRCm38
MGSCv37293,259,269 - 93,303,103 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36293,219,951 - 93,263,335 (-)NCBIMGSCv36mm8
Celera294,814,780 - 94,859,821 (-)NCBICelera
Cytogenetic Map2E1NCBI
cM Map251.62NCBI
Cd82
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554223,033,133 - 3,052,153 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554223,035,887 - 3,069,298 (-)NCBIChiLan1.0ChiLan1.0
CD82
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2946,780,583 - 46,836,160 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11146,786,918 - 46,842,472 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01144,526,010 - 44,581,560 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11145,020,362 - 45,075,876 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1145,020,319 - 45,075,876 (+)Ensemblpanpan1.1panPan2
CD82
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11844,658,414 - 44,707,897 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1844,659,180 - 44,706,768 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.01845,317,202 - 45,369,506 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1845,317,220 - 45,368,392 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11844,800,179 - 44,851,496 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01844,353,829 - 44,406,031 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01845,086,983 - 45,139,553 (-)NCBIUU_Cfam_GSD_1.0
Cd82
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494721,960,790 - 21,973,529 (-)NCBIHiC_Itri_2
CD82
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl217,750,660 - 17,803,126 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1217,751,153 - 17,803,172 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2219,249,749 - 19,264,391 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CD82
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1120,736,216 - 20,793,943 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl120,735,287 - 20,763,160 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038117,969,772 - 118,024,761 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd82
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247673,556,128 - 3,589,956 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cd82
212 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:393
Count of miRNA genes:215
Interacting mature miRNAs:252
Transcripts:ENSRNOT00000000052
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)364655305115665732Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)364655305115665732Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)36113434889115068Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat

Markers in Region
RH127894  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2379,387,524 - 79,387,715 (+)MAPPERmRatBN7.2
Rnor_6.0382,324,509 - 82,324,699NCBIRnor6.0
Rnor_5.0389,026,279 - 89,026,469UniSTSRnor5.0
RGSC_v3.4377,831,931 - 77,832,121UniSTSRGSC3.4
Celera378,589,696 - 78,589,886UniSTS
RH 3.4 Map3685.5UniSTS
Cytogenetic Map3q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000000052   ⟹   ENSRNOP00000000052
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl379,387,361 - 79,431,782 (-)Ensembl
Rnor_6.0 Ensembl382,324,354 - 82,368,357 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097921   ⟹   ENSRNOP00000078723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl379,387,367 - 79,431,310 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100406   ⟹   ENSRNOP00000084636
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl379,387,367 - 79,431,311 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119233   ⟹   ENSRNOP00000091451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl379,385,887 - 79,431,809 (-)Ensembl
RefSeq Acc Id: NM_031797   ⟹   NP_113985
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,842,752 - 99,886,744 (-)NCBI
mRatBN7.2379,387,365 - 79,431,358 (-)NCBI
Rnor_6.0382,324,349 - 82,368,357 (-)NCBI
Rnor_5.0389,026,114 - 89,070,616 (-)NCBI
RGSC_v3.4377,831,771 - 77,875,764 (-)RGD
Celera378,589,536 - 78,633,414 (-)RGD
Sequence:
RefSeq Acc Id: XM_006234597   ⟹   XP_006234659
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,842,748 - 99,887,208 (-)NCBI
mRatBN7.2379,387,370 - 79,431,805 (-)NCBI
Rnor_6.0382,324,344 - 82,368,794 (-)NCBI
Rnor_5.0389,026,114 - 89,070,616 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006234598   ⟹   XP_006234660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,842,748 - 99,887,298 (-)NCBI
mRatBN7.2379,387,370 - 79,431,847 (-)NCBI
Rnor_6.0382,324,344 - 82,368,846 (-)NCBI
Rnor_5.0389,026,114 - 89,070,616 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105948   ⟹   XP_038961876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,842,748 - 99,861,087 (-)NCBI
mRatBN7.2379,387,370 - 79,405,697 (-)NCBI
RefSeq Acc Id: XM_039105951   ⟹   XP_038961879
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,842,748 - 99,850,372 (-)NCBI
mRatBN7.2379,387,361 - 79,394,473 (-)NCBI
RefSeq Acc Id: XM_039105953   ⟹   XP_038961881
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8399,842,748 - 99,849,601 (-)NCBI
mRatBN7.2379,387,361 - 79,394,209 (-)NCBI
RefSeq Acc Id: NP_113985   ⟸   NM_031797
- UniProtKB: O70352 (UniProtKB/Swiss-Prot),   Q6IN14 (UniProtKB/TrEMBL),   A6HNI9 (UniProtKB/TrEMBL),   F7EV99 (UniProtKB/TrEMBL),   A0A8I5ZZR7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234660   ⟸   XM_006234598
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006234659   ⟸   XM_006234597
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000000052   ⟸   ENSRNOT00000000052
RefSeq Acc Id: XP_038961879   ⟸   XM_039105951
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038961881   ⟸   XM_039105953
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038961876   ⟸   XM_039105948
- Peptide Label: isoform X2
- UniProtKB: A6HNJ0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078723   ⟸   ENSRNOT00000097921
Ensembl Acc Id: ENSRNOP00000084636   ⟸   ENSRNOT00000100406
Ensembl Acc Id: ENSRNOP00000091451   ⟸   ENSRNOT00000119233

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O70352-F1-model_v2 AlphaFold O70352 1-266 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692232
Promoter ID:EPDNEW_R2756
Type:initiation region
Name:Cd82_1
Description:Cd82 molecule
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0382,368,340 - 82,368,400EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69070 AgrOrtholog
BioCyc Gene G2FUF-48668 BioCyc
Ensembl Genes ENSRNOG00000000047 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000052.5 UniProtKB/TrEMBL
  ENSRNOT00000097921.1 UniProtKB/TrEMBL
  ENSRNOT00000100406.1 UniProtKB/TrEMBL
  ENSRNOT00000119233.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1450.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7096826 IMAGE-MGC_LOAD
InterPro Tetraspanin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tetraspanin/Peripherin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tetraspanin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tetraspanin_EC2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:83628 UniProtKB/TrEMBL
MGC_CLONE MGC:91618 IMAGE-MGC_LOAD
NCBI Gene 83628 ENTREZGENE
PANTHER CD82 ANTIGEN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR19282 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Tetraspanin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cd82 PhenoGen
PIRSF Tetraspanin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS TMFOUR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TM4_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000047 RatGTEx
Superfamily-SCOP SSF48652 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC229731
UniProt A0A8I5ZP15_RAT UniProtKB/TrEMBL
  A0A8I5ZZR7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJM9_RAT UniProtKB/TrEMBL
  A6HNI9 ENTREZGENE, UniProtKB/TrEMBL
  A6HNJ0 ENTREZGENE, UniProtKB/TrEMBL
  CD82_RAT UniProtKB/Swiss-Prot
  F7EV99 ENTREZGENE, UniProtKB/TrEMBL
  O70352 ENTREZGENE
  Q6IN14 ENTREZGENE
UniProt Secondary Q6IN14 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-29 Cd82  Cd82 molecule  Cd82  CD82 antigen  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Cd82  CD82 antigen  Kai1  kangai 1  Symbol and Name updated 1299863 APPROVED
2004-12-14 Kai1  kangai 1      Symbol and Name status set to approved 1299863 APPROVED
2002-06-10 Kai1  kangai 1      Name updated 70585 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_disease down-regulated in squamous cell carcinomas 68869
gene_disease down-regulated in squamous cell carcinomas 70284
gene_disease 2.0-kb mRNA is associated with high metastatic ability by prostate cancer cells; 1.8-kb transcript is upregulated but not associated with metastasis 68869
gene_disease 2.0-kb mRNA is associated with high metastatic ability by prostate cancer cells; 1.8-kb transcript is upregulated but not associated with metastasis 70284
gene_disease expression not found in some low-grade and high-grade lymphomas 68869
gene_disease expression not found in some low-grade and high-grade lymphomas 70284
gene_expression expressed in squamous cell carcinomas 68869
gene_expression expressed in squamous cell carcinomas 70284
gene_process suppresses the metastatic potential of prostate cancer cells 68869
gene_process suppresses the metastatic potential of prostate cancer cells 70284
gene_product glycoprotein that belongs to the transmembrane 4 superfamily (TM4SF) 68869
gene_product glycoprotein that belongs to the transmembrane 4 superfamily (TM4SF) 70284
gene_transcript expresses a predominant 2.0-kb and a minor 1.8-kb-sized RNA 70284