St3gal3 (ST3 beta-galactoside alpha-2,3-sialyltransferase 3) - Rat Genome Database

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Advanced Search (OLGA)
Gene: St3gal3 (ST3 beta-galactoside alpha-2,3-sialyltransferase 3) Rattus norvegicus
Analyze
Symbol: St3gal3
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 3
RGD ID: 68414
Description: Predicted to enable beta-galactoside (CMP) alpha-2,3-sialyltransferase activity. Predicted to be involved in ganglioside biosynthetic process via lactosylceramide and protein glycosylation. Predicted to be located in Golgi cisterna membrane and extracellular region. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 12 and developmental and epileptic encephalopathy 15. Orthologous to human ST3GAL3 (ST3 beta-galactoside alpha-2,3-sialyltransferase 3); PARTICIPATES IN keratan sulfate biosynthetic pathway; lacto-series glycosphingolipid metabolic pathway; O-linked glycan biosynthetic pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: alpha 2,3-ST 3; beta-galactoside alpha-2,3-sialyltransferase 3; CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase; gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase; N-acetyllacosaminide alpha 2,3-sialyltransferase; N-acetyllactosaminide alpha-2,3-sialyltransferase; sialyltransferase (N-acetyllacosaminide alpha 23-sialyltransferase); sialyltransferase 6; sialyltransferase 6 (N-acetyllacosaminide alpha 2,3-sialyltransferase); sialyltransferase 6(N-acetyllacosaminide alpha 2,3-sialyltransferase); sialyltransferase 6(N-acetyllacosaminide alpha 23-sialyltransferase); Siat6; ST3Gal III; ST3GalIII; ST3N
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85136,755,780 - 136,958,081 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5136,755,678 - 136,955,987 (-)EnsemblGRCr8
mRatBN7.25131,470,348 - 131,670,794 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5131,470,348 - 131,670,810 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5134,176,350 - 134,378,439 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05135,930,969 - 136,133,076 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05135,953,391 - 136,155,481 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05136,765,309 - 136,965,642 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5136,766,208 - 136,965,191 (-)Ensemblrn6Rnor6.0
Rnor_5.05140,554,358 - 140,753,581 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45138,397,472 - 138,599,287 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5130,019,450 - 130,217,682 (-)NCBICelera
RGSC_v3.15138,402,697 - 138,604,513 (-)NCBI
Cytogenetic Map5q36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2-acetamidofluorene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
Azoxymethane  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
Butylbenzyl phthalate  (EXP)
C60 fullerene  (EXP)
casticin  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
cisplatin  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
fenarimol  (EXP)
fenthion  (ISO)
formaldehyde  (ISO)
furan  (EXP)
gentamycin  (EXP)
hydrogen cyanide  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
hypochlorous acid  (ISO)
inulin  (ISO)
lithocholic acid  (ISO)
methidathion  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
potassium cyanide  (ISO)
propanal  (ISO)
propiconazole  (EXP,ISO)
resveratrol  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
theophylline  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tributylstannane  (EXP)
triphenyl phosphate  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Primary structure of Gal beta 1,3(4)GlcNAc alpha 2,3-sialyltransferase determined by mass spectrometry sequence analysis and molecular cloning. Evidence for a protein motif in the sialyltransferase gene family. Wen DX, etal., J Biol Chem 1992 Oct 15;267(29):21011-9.
Additional References at PubMed
PMID:9184827   PMID:20824144  


Genomics

Comparative Map Data
St3gal3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85136,755,780 - 136,958,081 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5136,755,678 - 136,955,987 (-)EnsemblGRCr8
mRatBN7.25131,470,348 - 131,670,794 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5131,470,348 - 131,670,810 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5134,176,350 - 134,378,439 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05135,930,969 - 136,133,076 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05135,953,391 - 136,155,481 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05136,765,309 - 136,965,642 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5136,766,208 - 136,965,191 (-)Ensemblrn6Rnor6.0
Rnor_5.05140,554,358 - 140,753,581 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45138,397,472 - 138,599,287 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5130,019,450 - 130,217,682 (-)NCBICelera
RGSC_v3.15138,402,697 - 138,604,513 (-)NCBI
Cytogenetic Map5q36NCBI
ST3GAL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38143,707,536 - 43,931,159 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl143,705,824 - 43,931,167 (+)Ensemblhg38GRCh38
GRCh37144,173,207 - 44,396,831 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36143,945,805 - 44,169,418 (+)NCBIBuild 36Build 36hg18NCBI36
Celera142,455,047 - 42,680,364 (+)NCBICelera
Cytogenetic Map1p34.1NCBI
HuRef142,293,634 - 42,515,711 (+)NCBIHuRef
CHM1_1144,289,496 - 44,513,069 (+)NCBICHM1_1
T2T-CHM13v2.0143,578,028 - 43,802,236 (+)NCBIT2T-CHM13v2.0
St3gal3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394117,789,349 - 117,992,169 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4117,789,351 - 117,992,111 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm384117,932,152 - 118,134,972 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4117,932,154 - 118,134,914 (-)Ensemblmm10GRCm38
MGSCv374117,604,758 - 117,807,519 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364117,430,086 - 117,632,822 (-)NCBIMGSCv36mm8
Celera4116,647,820 - 116,857,856 (-)NCBICelera
Cytogenetic Map4D1- D2.1NCBI
cM Map453.84NCBI
St3gal3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555373,258,076 - 3,458,742 (+)Ensembl
ChiLan1.0NW_0049555373,258,076 - 3,458,742 (+)NCBIChiLan1.0ChiLan1.0
ST3GAL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21182,878,513 - 183,104,460 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11182,019,836 - 182,245,213 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,006,963 - 43,232,968 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1144,409,904 - 44,603,658 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl144,409,904 - 44,603,658 (+)EnsemblpanPan2panpan1.1
ST3GAL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11516,324,752 - 16,434,256 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1516,324,899 - 16,401,616 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1516,445,523 - 16,643,025 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01516,479,182 - 16,676,777 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1516,479,317 - 16,652,728 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11516,278,024 - 16,475,534 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01516,347,032 - 16,543,790 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01516,419,773 - 16,617,308 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
St3gal3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505859,234,110 - 59,423,591 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647425,058,892 - 25,248,378 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647425,058,892 - 25,248,378 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ST3GAL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6167,363,347 - 167,595,835 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16167,363,348 - 167,596,892 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26154,849,032 - 154,958,719 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ST3GAL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12088,875,525 - 89,108,001 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603327,817,002 - 28,051,211 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
St3gal3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248922,984,351 - 3,213,021 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248922,984,329 - 3,213,017 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
St3gal3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1138,887,386 - 39,091,287 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in St3gal3
1123 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:117
Count of miRNA genes:96
Interacting mature miRNAs:103
Transcripts:ENSRNOT00000056842
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
2303586Gluco52Glucose level QTL 522blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)5100826632145826632Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5130678987145274255Rat
7365049Bp359Blood pressure QTL 359arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133308734140009902Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5134369218156289444Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5110770739155770739Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)592583776137583776Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)598972960143972960Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
2303618Vencon1Ventilatory control QTL 13.8respiration trait (VT:0001943)oxygen consumption (CMO:0002169)5100826632145826632Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5111236572156236572Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)594034903139034903Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5125969677156302135Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)592881678137881678Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat

Markers in Region
D5Rat167  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85136,867,324 - 136,867,456 (+)Marker Load Pipeline
mRatBN7.25131,581,900 - 131,582,032 (+)MAPPERmRatBN7.2
Rnor_6.05136,876,851 - 136,876,982NCBIRnor6.0
Rnor_5.05140,665,553 - 140,665,684UniSTSRnor5.0
RGSC_v3.45138,509,021 - 138,509,387RGDRGSC3.4
RGSC_v3.45138,509,215 - 138,509,346UniSTSRGSC3.4
Celera5130,129,965 - 130,130,096UniSTS
RGSC_v3.15138,514,441 - 138,514,572RGD
RH 3.4 Map5858.2UniSTS
RH 3.4 Map5858.2RGD
RH 2.0 Map5853.1RGD
SHRSP x BN Map570.6499RGD
Cytogenetic Map5q36UniSTS
BF410540  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25131,666,124 - 131,666,287 (+)MAPPERmRatBN7.2
Rnor_6.05136,961,021 - 136,961,183NCBIRnor6.0
Rnor_5.05140,749,367 - 140,749,529UniSTSRnor5.0
RGSC_v3.45138,595,117 - 138,595,279UniSTSRGSC3.4
Celera5130,213,512 - 130,213,674UniSTS
RH 3.4 Map5860.2UniSTS
Cytogenetic Map5q36UniSTS
AI169573  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25131,586,261 - 131,586,361 (+)MAPPERmRatBN7.2
Rnor_6.05136,881,212 - 136,881,311NCBIRnor6.0
Rnor_5.05140,669,914 - 140,670,013UniSTSRnor5.0
RGSC_v3.45138,513,576 - 138,513,675UniSTSRGSC3.4
Celera5130,134,326 - 130,134,425UniSTS
RH 3.4 Map5860.8UniSTS
Cytogenetic Map5q36UniSTS
BQ205479  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25131,671,841 - 131,672,031 (+)MAPPERmRatBN7.2
Rnor_6.05136,966,738 - 136,966,927NCBIRnor6.0
Rnor_5.05140,755,084 - 140,755,273UniSTSRnor5.0
RGSC_v3.45138,600,834 - 138,601,023UniSTSRGSC3.4
Celera5130,219,229 - 130,219,418UniSTS
RH 3.4 Map5854.9UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
20 13 76 190 91 90 59 152 59 6 466 272 23 167 107 108 31 27 27

Sequence


Ensembl Acc Id: ENSRNOT00000056842   ⟹   ENSRNOP00000053685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5136,755,678 - 136,955,719 (-)Ensembl
mRatBN7.2 Ensembl5131,470,348 - 131,670,295 (-)Ensembl
Rnor_6.0 Ensembl5136,766,208 - 136,965,191 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097514   ⟹   ENSRNOP00000086704
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5136,755,678 - 136,955,719 (-)Ensembl
mRatBN7.2 Ensembl5131,470,348 - 131,670,295 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106433   ⟹   ENSRNOP00000086133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5136,756,430 - 136,955,987 (-)Ensembl
mRatBN7.2 Ensembl5131,470,348 - 131,670,810 (-)Ensembl
RefSeq Acc Id: NM_031697   ⟹   NP_113885
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85136,756,679 - 136,955,719 (-)NCBI
mRatBN7.25131,471,247 - 131,670,295 (-)NCBI
Rnor_6.05136,766,208 - 136,965,191 (-)NCBI
Rnor_5.05140,554,358 - 140,753,581 (-)NCBI
RGSC_v3.45138,397,472 - 138,599,287 (-)RGD
Celera5130,019,450 - 130,217,682 (-)RGD
Sequence:
RefSeq Acc Id: XM_006238715   ⟹   XP_006238777
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85136,755,780 - 136,956,217 (-)NCBI
mRatBN7.25131,470,348 - 131,670,794 (-)NCBI
Rnor_6.05136,765,309 - 136,965,642 (-)NCBI
Rnor_5.05140,554,358 - 140,753,581 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006238716   ⟹   XP_006238778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85136,755,780 - 136,956,216 (-)NCBI
mRatBN7.25131,470,348 - 131,670,794 (-)NCBI
Rnor_6.05136,765,309 - 136,965,642 (-)NCBI
Rnor_5.05140,554,358 - 140,753,581 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039110705   ⟹   XP_038966633
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85136,755,780 - 136,956,004 (-)NCBI
mRatBN7.25131,470,348 - 131,670,583 (-)NCBI
RefSeq Acc Id: XM_039110706   ⟹   XP_038966634
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85136,755,780 - 136,956,215 (-)NCBI
mRatBN7.25131,470,348 - 131,670,583 (-)NCBI
RefSeq Acc Id: XM_063288347   ⟹   XP_063144417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85136,838,358 - 136,958,081 (-)NCBI
RefSeq Acc Id: XM_063288348   ⟹   XP_063144418
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85136,838,358 - 136,930,863 (-)NCBI
RefSeq Acc Id: XM_063288349   ⟹   XP_063144419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85136,838,358 - 136,930,919 (-)NCBI
RefSeq Acc Id: XM_063288350   ⟹   XP_063144420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85136,755,780 - 136,956,216 (-)NCBI
RefSeq Acc Id: NP_113885   ⟸   NM_031697
- UniProtKB: Q02734 (UniProtKB/Swiss-Prot),   A6JZG3 (UniProtKB/TrEMBL),   F1LM32 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238777   ⟸   XM_006238715
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006238778   ⟸   XM_006238716
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000053685   ⟸   ENSRNOT00000056842
RefSeq Acc Id: XP_038966634   ⟸   XM_039110706
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038966633   ⟸   XM_039110705
- Peptide Label: isoform X5
Ensembl Acc Id: ENSRNOP00000086133   ⟸   ENSRNOT00000106433
Ensembl Acc Id: ENSRNOP00000086704   ⟸   ENSRNOT00000097514
RefSeq Acc Id: XP_063144420   ⟸   XM_063288350
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A473 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144417   ⟸   XM_063288347
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063144419   ⟸   XM_063288349
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063144418   ⟸   XM_063288348
- Peptide Label: isoform X3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q02734-F1-model_v2 AlphaFold Q02734 1-374 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68414 AgrOrtholog
BioCyc Gene G2FUF-40174 BioCyc
Ensembl Genes ENSRNOG00000019843 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000056842 ENTREZGENE
  ENSRNOT00000097514 ENTREZGENE
  ENSRNOT00000106433 ENTREZGENE
Gene3D-CATH 3.90.1480.20 UniProtKB/Swiss-Prot
InterPro Glyco_trans_29 UniProtKB/Swiss-Prot
  Glycosyltransferase_29 UniProtKB/Swiss-Prot
  GT29-like_sf UniProtKB/Swiss-Prot
  Sialyl_trans UniProtKB/Swiss-Prot
KEGG Report rno:64445 UniProtKB/Swiss-Prot
NCBI Gene 64445 ENTREZGENE
PANTHER CMP-N-ACETYLNEURAMINATE-BETA-1,4-GALACTOSIDE ALPHA-2,3-SIALYLTRANSFERASE UniProtKB/Swiss-Prot
  SIALYLTRANSFERASE UniProtKB/Swiss-Prot
Pfam Glyco_transf_29 UniProtKB/Swiss-Prot
PhenoGen St3gal3 PhenoGen
PIRSF Sialyl_trans UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019843 RatGTEx
UniProt A0A8I6A473 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GDQ1 ENTREZGENE, UniProtKB/TrEMBL
  A6JZG3 ENTREZGENE, UniProtKB/TrEMBL
  F1LM32 ENTREZGENE, UniProtKB/TrEMBL
  Q02734 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 St3gal3  ST3 beta-galactoside alpha-2,3-sialyltransferase 3  Siat6  sialyltransferase 6 (N-acetyllacosaminide alpha 2,3-sialyltransferase)  Symbol and Name updated 1299863 APPROVED
2004-09-10 Siat6  sialyltransferase 6 (N-acetyllacosaminide alpha 2,3-sialyltransferase)    sialyltransferase 6  Name updated 1299863 APPROVED
2002-06-10 Siat6  sialyltransferase 6      Name updated 70584 APPROVED
2002-02-20 Siat6  sialyltransferase 6(N-acetyllacosaminide alpha 2,3-sialyltransferase)      Name updated to reflect Human and Mouse nomenclature 70282 APPROVED

RGD Curation Notes
Note Type Note Reference