Gene: ST3GAL3 (ST3 beta-galactoside alpha-2,3-sialyltransferase 3)  Homo sapiens

Symbol: ST3GAL3
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 3
Description: The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with autosomal recessive nonsymdromic mental retardation-12 (MRT12). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha 2,3-sialyltransferase III; alpha 2,3-ST 3; alpha-2,3-sialyltransferase II; beta-galactoside alpha-2,3-sialyltransferase 3; CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase; EIEE15; gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase; Gal beta-1,3(4)GlcNAc alpha-2,3 sialyltransferase; MRT12; N-acetyllactosaminide alpha-2,3-sialyltransferase; OTTHUMP00000008811; OTTHUMP00000008812; OTTHUMP00000008813; OTTHUMP00000008814; OTTHUMP00000008815; OTTHUMP00000008816; OTTHUMP00000008817; OTTHUMP00000008819; OTTHUMP00000008820; OTTHUMP00000008821; OTTHUMP00000008822; OTTHUMP00000008823; OTTHUMP00000231087; OTTHUMP00000231088; OTTHUMP00000231089; OTTHUMP00000231091; OTTHUMP00000231092; OTTHUMP00000231094; OTTHUMP00000231096; OTTHUMP00000231140; OTTHUMP00000231141; sialyltransferase 6 (N-acetyllacosaminide alpha 2,3-sialyltransferase); SIAT6; ST3Gal III; ST3GALII; ST3GalIII; ST3N
Orthologs: Mus musculus : St3gal3 (ST3 beta-galactoside alpha-2,3-sialyltransferase 3)  MGI
Rattus norvegicus : St3gal3 (ST3 beta-galactoside alpha-2,3-sialyltransferase 3)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1144,251,826 - 44,474,973+NCBI
Human Genome Assembly HuRef142,293,634 - 42,515,711+NCBI
Human Genome Assembly GRCh37144,173,204 - 44,396,837+NCBI
Human Genome Assembly Build 36143,945,805 - 44,169,418+NCBI
Human Cytogenetic Map1p34.1 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on ST3GAL3
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1603708
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2013-04-09
Status: ACTIVE