Gene:	Ctbp2 ( Rattus norvegicus ) C-terminal binding protein 2
Description:	gene produces two transcripts; one protein is a transcriptional repressor, while the other isoform is a major component of synaptic ribbons
ArrayIDs:	GE13481; 6588182; 6499245; 1383718_at; 6359836; 5822223; 6262042; 1387113_at; 6623530; 5755222; 6067368; 6204677; 6576132; 5875750; rc_AA964253_at; 5964280; rc_AI011604_at; 5869325; 5853619; rc_AI169011_at; 6601156; 5888853; A_43_P12773; 5676326;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: CTBP2     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Ctbp2     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Ctbp2 genome assembly 3.1 1 192613495 - 192642816     Rat Celera Assembly 1 185527008 - 185555538     RGSC genome assembly v3.4 1 192463615 - 192492934     Cytogenetic 1 q41 Mus musculus Ctbp2 Mouse genome assembly build 36.1 7 140178694 - 140315166     Cytogenetic 7 7 F3 Homo sapiens CTBP2 human genome assembly 10 126667390 - 126706443     Human genome assembly build 36.2 10 126667391 - 126839019     Cytogenetic 10 q26.13   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology transcription corepressor activity,  protein binding (details...)
Biological Process	Gene Ontology white fat cell differentiation,  negative regulation of transcription, DNA-dependent (details...)
Cellular Component	Gene Ontology nucleus,  transcriptional repressor complex (details...)
Domain	Note Reference contains an A domain specific for ribbons, and a B domain identical with CtBP2, a transcriptional repressor that in turn is related to 2-hydroxyacid dehydrogenases 68229
External Links
Databases	DATABASE ID SOURCE PROSITE: D_2_HYOXYACID_DH_3 IPI UNIPARC: UPI00000E6533 IPI UNIPARC: UPI000019C022 IPI UNIPARC: UPI0000DC2269 IPI KEGG Report: rno:81717 ENTREZGENE HomoloGene Group ID: 75187 ENTREZGENE Germonline: 68372 Pfam: 2-Hacid_dh_C IPI Pfam: 2-Hacid_dh IPI KEGG Pathway: 05220 ENTREZGENE KEGG Pathway: 04330 ENTREZGENE KEGG Pathway: 04310 ENTREZGENE InterPro: NAD(P)-bd_dom. IPI InterPro: D-isomer_2_OHA_DH_NAD-bd. IPI InterPro: D-isomer_2_OHA_DH. IPI IPI: IPI00780712 IPI IPI: IPI00189984 IPI IPI: IPI00476123 IPI Ensembl Protein: ENSRNOP00000023574 IPI Ensembl Protein: ENSRNOP00000051785 IPI Ensembl Protein: ENSRNOP00000023404 IPI Gene3D-CATH: NAD(P)-bd IPI Entrez Gene: Ctbp2 ENTREZGENE TIGR: TC204483 UniProt: CTBP2_RAT IPI UniProt: CTBP2_RAT IPI Ensembl Genes: ENSRNOG00000017326 IPI Superfamily-SCOP: NAD(P)-bd IPI
Sequences	Nucleotide: CH473953 Get FASTA Search GEO Profiles Nucleotide: AF222712 Get FASTA Search GEO Profiles Nucleotide: NM_053335 Get FASTA Search GEO Profiles (View all 3 Nucleotide Accessions) Protein: EDM11743 Get FASTA Protein: EDM11744 Get FASTA Protein: EDM11745 Get FASTA Protein: EDM11746 Get FASTA Protein: AAG45952 Get FASTA Protein: Q9EQH5 Get FASTA Protein: NP_445787 Get FASTA (View all 7 Protein Accessions)
Clusters	UniGene: 138124
References
Curated References	6 references in RGD related to Ctbp2
Other References	1 other references at PubMed related to Ctbp2
Database Information
RGD ID	68372
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 10-JUN-02: Ctbp2 C-terminal binding protein 2 APPROVED Name updated 70584