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Gene: Pdcd6ip (programmed cell death 6 interacting protein) Rattus norvegicus

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Symbol:

Pdcd6ip

Name:

programmed cell death 6 interacting protein

RGD ID:

68357

Description:

Enables SH3 domain binding activity. Predicted to be involved in several processes, including bicellular tight junction assembly; cytokinetic process; and positive regulation of cellular component biogenesis. Located in neuronal cell body and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 29. Orthologous to human PDCD6IP (programmed cell death 6 interacting protein); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

AIP1; ALG-2 interacting protein 1; ALG-2 interacting protein X; ALG-2-interacting protein 1; Alix; programmed cell death 6-interacting protein; RGD1561176

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	122,469,223 - 122,524,993 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	122,469,223 - 122,524,993 (-)	Ensembl				GRCr8
mRatBN7.2	8	113,590,998 - 113,646,795 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	113,590,998 - 113,646,773 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	119,207,150 - 119,262,921 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	117,406,414 - 117,462,188 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	115,249,172 - 115,304,948 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	121,916,233 - 121,973,145 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	121,916,185 - 121,973,125 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	121,231,793 - 121,287,105 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	118,314,910 - 118,350,134 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	112,840,809 - 112,895,775 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

osteoarthritis (ISO)

primary autosomal recessive microcephaly 29 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1,4-dithiothreitol (ISO)

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-hydroxy-17-methylestra-4,9,11-trien-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dimethoxyphenol (ISO)

2,6-dinitrotoluene (EXP)

2-bromohexadecanoic acid (ISO)

2-hydroxypropanoic acid (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid (ISO)

4,4'-sulfonyldiphenol (ISO)

5-fluorouracil (ISO)

acrolein (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

antimycin A (ISO)

aristolochic acid A (ISO)

arsenous acid (ISO)

atrazine (ISO)

azoxystrobin (ISO)

beauvericin (ISO)

benzo[a]pyrene (EXP,ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

Brodifacoum (EXP)

butyric acid (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

Cuprizon (EXP)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dibenz[a,h]anthracene (EXP)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

dioxygen (ISO)

Enterolactone (ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

fenthion (ISO)

flavonoids (EXP)

flutamide (EXP)

folic acid (ISO)

furfural (ISO)

genistein (ISO)

gentamycin (EXP)

glafenine (EXP)

hesperetin (ISO)

Honokiol (ISO)

indometacin (ISO)

ivermectin (ISO)

L-1,4-dithiothreitol (ISO)

methapyrilene (EXP)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

morusin (ISO)

N-acetyl-L-cysteine (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

nitric oxide (ISO)

oxybenzone (EXP)

ozone (ISO)

paracetamol (ISO)

phenobarbital (ISO)

picoxystrobin (ISO)

poly(I:C) (EXP)

pyrene (EXP)

rac-lactic acid (ISO)

rotenone (EXP,ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sodium chloride (ISO)

sodium dichromate (EXP)

succimer (ISO)

thapsigargin (ISO)

titanium dioxide (ISO)

trichloroethene (ISO)

troglitazone (ISO)

tungsten (ISO)

uranium atom (ISO)

vinclozolin (EXP)

zearalenone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actomyosin contractile ring assembly (IEA,ISO,ISS)

apoptotic process (IEA)

bicellular tight junction assembly (IEA,ISO,ISS)

cell division (IEA)

extracellular exosome biogenesis (IEA,ISO,ISS)

macroautophagy (IEA,ISO,ISS)

maintenance of epithelial cell apical/basal polarity (IEA,ISO,ISS)

midbody abscission (ISO)

mitotic cytokinesis (IBA,ISO,ISS)

mitotic metaphase chromosome alignment (ISO)

nucleus organization (ISO)

positive regulation of exosomal secretion (ISO)

positive regulation of extracellular exosome assembly (ISO)

protein homooligomerization (ISO)

protein transport (IEA)

regulation of centrosome duplication (ISO)

regulation of extracellular exosome assembly (ISO)

regulation of membrane permeability (IEA,ISO,ISS)

regulation of mitotic spindle assembly (ISO)

ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway (ISO)

viral budding (ISO)

viral budding via host ESCRT complex (ISO)

Cellular Component

actomyosin (IEA,ISO,ISS)

bicellular tight junction (IEA)

centrosome (IEA,ISO)

cytoplasm (IEA)

cytosol (IEA,ISO)

endoplasmic reticulum exit site (ISO)

endosome (IBA)

extracellular exosome (IEA,ISO,ISS)

extracellular region (IEA)

Flemming body (IEA,ISO,ISS)

immunological synapse (ISO)

melanosome (IEA)

neuronal cell body (IDA)

perinuclear region of cytoplasm (IDA)

Molecular Function

calcium-dependent protein binding (ISO)

protein binding (ISO)

protein dimerization activity (IEA,ISO)

protein homodimerization activity (ISO)

proteinase activated receptor binding (ISO)

SH3 domain binding (IDA)

Molecular Pathway Annotations Click to see Annotation Detail View

endocytosis pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes.	Chen B, etal., J Biol Chem 2000 Jun 23;275(25):19275-81.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Early increase of apoptosis-linked gene-2 interacting protein X in areas of kainate-induced neurodegeneration.	Hemming FJ, etal., Neuroscience. 2004;123(4):887-95.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
8.	GOA pipeline	RGD automated data pipeline
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data

Additional References at PubMed

PMID:8889548	PMID:9880530	PMID:10200558	PMID:12771190	PMID:14505570	PMID:14519844	PMID:15086793	PMID:15326289	PMID:15557335	PMID:16501490	PMID:16957052	PMID:17634366
PMID:18641129	PMID:19056867	PMID:19199708	PMID:19520058	PMID:19523902	PMID:19706535	PMID:19946888	PMID:20616062	PMID:21276792	PMID:21423176	PMID:22547407	PMID:22660413
PMID:22871113	PMID:23092844	PMID:23376485	PMID:23523921	PMID:23533145	PMID:23924735	PMID:24105262	PMID:24107264	PMID:24769233	PMID:27336173	PMID:31077357

Genomics

Comparative Map Data

Pdcd6ip
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	122,469,223 - 122,524,993 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	122,469,223 - 122,524,993 (-)	Ensembl				GRCr8
mRatBN7.2	8	113,590,998 - 113,646,795 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	113,590,998 - 113,646,773 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	119,207,150 - 119,262,921 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	117,406,414 - 117,462,188 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	115,249,172 - 115,304,948 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	121,916,233 - 121,973,145 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	121,916,185 - 121,973,125 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	121,231,793 - 121,287,105 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	118,314,910 - 118,350,134 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	112,840,809 - 112,895,775 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

PDCD6IP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	33,798,630 - 33,869,703 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	33,798,571 - 33,869,707 (+)	Ensembl			hg38	GRCh38
GRCh37	3	33,840,122 - 33,911,195 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	33,814,561 - 33,886,198 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	33,814,560 - 33,886,198	NCBI
Celera	3	33,783,127 - 33,854,073 (+)	NCBI		Celera
Cytogenetic Map	3	p22.3	NCBI
HuRef	3	33,781,264 - 33,852,387 (+)	NCBI		HuRef
CHM1_1	3	33,789,988 - 33,861,201 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	33,799,362 - 33,870,437 (+)	NCBI		T2T-CHM13v2.0

Pdcd6ip
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	113,480,812 - 113,537,457 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	113,480,812 - 113,537,327 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	113,651,744 - 113,708,279 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	113,651,744 - 113,708,259 (-)	Ensembl			mm10	GRCm38
MGSCv37	9	113,560,862 - 113,617,377 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	113,503,631 - 113,556,805 (-)	NCBI		MGSCv36	mm8
Celera	9	113,360,961 - 113,417,417 (-)	NCBI		Celera
Cytogenetic Map	9	F3	NCBI
cM Map	9	64.03	NCBI

Pdcd6ip
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955421	1,034,843 - 1,110,438 (+)	Ensembl
ChiLan1.0	NW_004955421	1,034,843 - 1,109,637 (+)	NCBI	ChiLan1.0	ChiLan1.0

PDCD6IP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	33,773,923 - 33,847,614 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	33,778,883 - 33,852,381 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	33,719,603 - 33,793,301 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	34,016,152 - 34,093,631 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	34,016,474 - 34,093,631 (+)	Ensembl			panPan2	panpan1.1

PDCD6IP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	4,112,299 - 4,199,230 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	4,112,363 - 4,196,342 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	4,154,337 - 4,240,985 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	4,374,570 - 4,462,420 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	4,374,544 - 4,462,418 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	4,207,505 - 4,294,589 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	4,339,176 - 4,426,011 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	4,308,530 - 4,395,465 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pdcd6ip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	190,870,278 - 190,948,263 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936473	24,010,935 - 24,086,846 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936473	24,010,942 - 24,086,836 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PDCD6IP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	19,597,059 - 19,665,996 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	19,597,064 - 19,664,047 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	21,193,109 - 21,243,506 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PDCD6IP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	78,265,099 - 78,339,307 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	78,265,252 - 78,339,873 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	51,646,595 - 51,721,427 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pdcd6ip
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624788	11,772,396 - 11,845,765 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624788	11,772,268 - 11,849,040 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pdcd6ip
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	8	104,517,761 - 104,572,534 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pdcd6ip
791 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	383
Count of miRNA genes:	227
Interacting mature miRNAs:	288
Transcripts:	ENSRNOT00000012114
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	105462581	132782436	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	82352698	127352698	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	80768445	125768445	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	80768445	125768445	Rat
10450865	Bw175	Body weight QTL 175	4.1		total fat pad mass (VT:0015008)	adipose tissue molecular composition measurement (CMO:0000484)	8	84192326	129192326	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	102413464	132782436	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	103375781	129871912	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	55428333	127966348	Rat
634332	Pia18	Pristane induced arthritis QTL 18	4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	84192326	132782436	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	85348065	130348065	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	79394435	132782436	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	98145073	122898010	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	80768445	125768445	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	80768445	125768445	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	91340911	131690273	Rat

Markers in Region

RH127559

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	113,593,711 - 113,593,931 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	121,918,947 - 121,919,166	NCBI	Rnor6.0
Rnor_5.0	8	121,234,507 - 121,234,726	UniSTS	Rnor5.0
Celera	8	112,843,523 - 112,843,742	UniSTS
RH 3.4 Map	8	1197.1	UniSTS
Cytogenetic Map	8	q32	UniSTS

C76364

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	113,593,843 - 113,594,060 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	121,919,079 - 121,919,295	NCBI	Rnor6.0
Rnor_5.0	8	121,234,639 - 121,234,855	UniSTS	Rnor5.0
Celera	8	112,843,655 - 112,843,871	UniSTS
Cytogenetic Map	8	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001029910	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006243997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF192757	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BQ198996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB773860	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK470082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO560641	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO573036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO574709	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CV109920	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EV768483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EX489547	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000012114 ⟹ ENSRNOP00000012114

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	8	122,469,223 - 122,524,993 (-)	Ensembl
mRatBN7.2 Ensembl	8	113,590,998 - 113,646,773 (-)	Ensembl
Rnor_6.0 Ensembl	8	121,916,185 - 121,973,125 (-)	Ensembl

RefSeq Acc Id:

NM_001029910 ⟹ NP_001025081

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	122,469,223 - 122,524,993 (-)	NCBI
mRatBN7.2	8	113,590,998 - 113,646,773 (-)	NCBI
Rnor_6.0	8	121,916,233 - 121,973,145 (-)	NCBI
Rnor_5.0	8	121,231,793 - 121,287,105 (-)	NCBI
RGSC_v3.4	8	118,314,910 - 118,350,134 (-)	RGD
Celera	8	112,840,809 - 112,895,775 (-)	RGD

Sequence:

show sequence

CCGGCTCCAAGCGCTGGCGGCCCAGTCCGTCGGCCCGTCGGTCCGCTCGTCCGCTGCCGGTGCC
GAGCGCGCCTAGGCCGTCGTCGCTGTCCCTTCGTCTGTCCGGCCCGAAGCGGCGGCCGGGCGCT
CACCATGGCGTCGTTCATCTGGGTGCAGCTGAAGAAGACCTCGGAGGTGGACCTGGCCAAGCCG
CTGGTCAAGTTCATCCAGCAGACGTACCCGAGCGGCGGCGAGGAGCAGGCCCAGTACTGCCGCG
CGGCCGAGGAGCTCAGCAAGCTGCGGCGCTCGGCGCTCGGCCGCCCGCTGGACAAGCACGAGGG
CGCGCTGGAGACGCTGCTGAGATATTATGACCAGATTTGTTCTATTGAACCCAAGTTCCCATTT
TCTGAAAATCAGATCTGCTTGACATTTACGTGGAAGGATGCTTTTGATAAAGGTTCCCTTTTTG
GAGGATCTGTAAAATTGGCTCTTGCAAGCTTAGGATATGAAAAGAGCTGTGTGTTGTTCAACTG
TGCTGCCTTAGCTAGCCAGATCGCAGCAGAGCAGAACCTGGATAATGATGAAGGACTGAAAACC
GCTGCTAAGCAGTACCAGTTTGCTAGTGGTGCCTTTTTACATATTAAAGACACAGTTTTATCTG
CCTTAAGTCGAGAGCCTACTGTGGACATATCTCCAGATACTGTGGGGACCCTCAGTCTTATTAT
GCTGGCCCAAGCTCAAGAAGTATTTTTCTTAAAAGCCACAAGAGATAAGATGAAGGATGCCATC
ATAGCGAAGCTGGCCAATCAGGCTGCCGATTACTTTGGCGATGCTTTCAAACAGTGTCAGTACA
AAGATGCCCTCCCCAAGGAGGTATTCCCTACCCTGGCTGCAAAGCAGTGCATCATGCAGGCTAA
TGCTGAGTACCACCAGTCCATCCTGGCCAAGCAGCAGAAGAAGTTTGGGGAAGAGATCGCAAGG
TTGCAGCATGCAGCAGAACTGATTAAGAATGTGGCCTCTCGCTATGATGAATATGTCAATGTGA
AGGATTTTTCTGACAAAATCAACCGTGCCCTGGCTGCAGCAAAGAAGGATAATGATTTTATTTA
TCATGACCGTGTTCCGGACCTTAAGGATCTGGATCCTATTGGCAAAGCCACGCTTGTGAAACCC
ACTCCAGTTAATGTACCCATCAGCCAGAAGTTCACGGATTTGTTTGAGAAGATGGTGCCTGTGT
CTGTGCAGCAGTCCCTGGCTGTGTTTAGTCAGAGGAAAGCTGACTTGGTTAACAGATCAATCGC
TCAGATGAGAGAAGCTACAACTTTGGCAAATGGAGTACTGGCTTCCCTTAACCTTCCAGCAGCA
ATTGAAGATGTGTCTGGAGACACTGTACCTCAGTCTATACTTACCAAGTCCACAGCTGTAGTCG
AGCAGGGAGGCATCCAGACTGTCGACCAGCTGATAAAAGAGCTGCCTGAGCTGCTACAAAGAAA
TAGGGAAATATTAGAGGAGTCACTAAGATTGTTGGATGAAGAAGAAGCAACTGATAATGACTTA
AGAGCAAAATTCAAGGACCGGTGGCAAAGGACTCCATCCAATGACCTGTACAAGCCTTTACGAG
CAGAGGGAGCCAAGTTCAGAGCCGTTTTAGATAAAGCGGTGCAAGCGGATGGACAGGTGAAGGA
GCGCTACCAGTCCCACCGAGACACCATCGCCCTTCTGTGTAAGCCAGAGCCGGAGCTGAATGCC
GCCATCCCTTCTGCTAACCCAGCAAAGACCATGCAGGGCAGTGAGGTTGTAAATGTCTTAAAAT
CCTTATTATCAAATCTTGATGAAATAAAGAAGGAAAGAGAGGGTCTTGAGAATGACCTGAAGTC
AGTGAATTTTGACATGACAAGCAAGTTTTTGACAGCTCTGGCCCAAGATGGCGTGATAAATGAG
GAGGCTCTTTCTGTCACTGAGCTGGATCGGATCTATGGTGGGCTAACAACTAAAGTTCAAGAGT
CTCTGAAGAAACAGGAGGGACTTCTAAAAAATATACAGGTCTCACACCAGGAATTCTCCAAAAT
GAAGCAGTCTAACAGTGAGGCCAGCCTGAGGGAAGAGGTCCTGAAGAACTTAGCGACCGCGTAC
GACAACTTCGTGGAGCTCGTAGCTAACTTGAAAGAGGGCACAAAGTTTTACAATGAGCTGACTG
AAATCCTGGTCAGGTTCCAGAACAAATGCAGTGACATAGTGTTTGCACGGAAGACGGAAAGAGA
TGAGCTCTTGAAGGATCTGCAGCAGAGCATTGCCAGAGAGCCCAGCGCTCCTTCTATCCCTCCG
CCAGCATATCAGTCCTCCCCAGCAGGGGGACATGCGACAGCTCCAACTCCAGCTCCAAGAACCA
TGCCGCCTGCTAAGCCCCAGCCTCCAGCCCGGCCTCCACCTCCTGTGCTTCCTGCAAACCGAGT
TCCTCCTGCTGCTGCCGCTACTGCCCCTGCAGGGGTGGGGACTGCTTCAGCAGCACCGCCACAG
ACCCCTGGCTCTGCTCCCCCTCCACAGGCTCAGGGACCACCGTATCCCACCTATCCAGGATATC
CCGGGTATTGCCAAATGCCCATGCCCATGGGCTACAACCCCTACACATATGGCCAGTACAATAT
GCCGTACCCACCGGTGTATCACCAGAGCCCTGGACAGGCTCCGTACCCAGGACCCCAGCAGCCT
ACCTACCCCTTCCCTCAGCCCCCGCAGCAGTCATACTATCCACAGCAGTAATGCCACCACGCGC
TGCTGGTTCAGATCAGAGCGACAGGACAGCGGCTGCCACCACGCTCTAAGCCACACTCTGGCCA
CTCGAGAATATCTCGCTCTCCTGATGCCTGTGGATGATTTCTGTCTGTGGATAAAACCGAAGGC
TGGGCCCCACCTCCACATTTGATCGCACTTGTGAGATTCTGCTGCTGTTGCAGCATAAACGCTA
GCTATGATAGCAATGGAAAAAATTACAGTTCCATAAAACGCTGAAAATGACAATTAAACCTGCA
AGTGAAACCTTTGAAATTAGCATACTTTATAAGATGAGGTTGGGACAAGGATGGCTTAAATACT
GATATTTAAGGAAAAAGTTTTCTTTCTCTTGGTTTATTGATTTAGTTTAATTTCTATTATGATA
TTTTGCATAATCAAGGCATTGTAAATCTTATAATTTAAAAATAAATTACTTACGAACAGTTGTC
ATTGTTATGGTTTGTCCTTGATTCTCATTGCTGTCTGATTCCTTTCTGGTGTTAGCCTCTCCTT
TGTATGTTCACAGGCTCCGTGTACTGTGTTGGACTGCATGGACTGCAGACTGGCAGTCAGGTGA
GGGCTGCCCTGAGAGCCCAAGCGCACCAGCTTGTCTGCCATACTCTCCTTAGTCAGTCCTGTTG
ACACTGATTTTTAAAAGTCCTATAATGTGGGAGACACACACAATTGTTACCAAAGATTCTTCAA
ATAAATATAAAATTTAAAAGTATGTATTTAATGTTTTATTATTAGATTTTCCAAGAAAATGATG
CAAATTCTGGTAATAATTCACTTCCCTTACCCATAATCCGGTCAAAGTGAGTAGTTTTAGCCGT
ACAGTGCCAGGATGTGTAGAGCCTGGCGAAAGCTCCTGTGCCTTTCTCGTCCTTGGCTCCATCT
ACTCTTGTCCTGTGATGGTGACTGTGCGCAGTGTACTGGAACAGATCTTCTTAACCCTTCTTTT
CAAATTTCATATTATGATTTTTTATTTTCTGTGGTTCCTGGAAGCTGAGGTTATTCTGTAATCC
AGGAGCATGTAAGACAATTGGTGGGGCTGCGTGCAAGCCCCAAACAGTGAGGTCTCGGGGGCTC
TGCCTGTGCGAGGCTCTTGTCCAACAGAACAGGCGTACAGACAGATTTCCTAATCTGTGTTTGT
CTTCTAAGTTTAATGCTGACATCTTGTTTCTCATCTCGTTTAAATGATACTGTCACTTAGTCCT
CATTGCTCTCAATGACAATTCAGGCTGATACTTTCAAATGTAAGACTGAAGATACGATTGTACA
AGGGAGTAAACTGGTTTAAATGTGTGTATTTAAAGCTCCGTGCTTTGTTGTATGCAGAAAACAC
AGACCAATCGCCGGGAATGTGGACATTGGCTTAAACCTCGACAAAACGTAACAAACGTGCCATT
GCTCAGCTCCGTGCTCCGCGGTACTCGGTGTATGAGACAGTGTATTTGAATCCTCTGTAAATGC
ATTTGAATTTTATATTCTCCCCTCCTGAGTTCTTATACTGACACGAGACATCCCCCGAGTTAGG
GAGCTCCCAGACTGCTAGTGTATTCCTTACTAATGCAAAACAACCACCAAAAGAAAAAAATAGA
AAAAAGAAAAAAAAAGTGGCCTGAATATTCTCTTGGGGAAAGGGGGTTGGAGGTCTAACGGGAA
GGGCAAGTGCATCAGAGAGCCAAAGGGAGGAGGGGTCAGGCCGGCGGCCATTTCCTCCTGCCCT
GTGCTATGCTTCCAGGCTCACAGCGGACAGTCAGCGGGGGAGGGCCCCTTCCAGTTGCCTCCCA
GCTCAGCTCCTGAGGGAAGCCTCTTGCCAGGTGTCTCCCCCTTCACGCTGCTCAGGATGCTCCG
GTCTCGGGTCAGGTGCCCTTACCCTGCAGCGCCAACTTTGCCTTCCTAGGCCTGTTCGGTTTGC
TGGCCGGAAGCCTCCTCATGCGCCTGTTGTCTAGATGGCGTCCCTCACCATCAGCACACCCTAA
CTGTGCTCCGTTGGCTGTGCTCTTTAGAACACACTGCAGAAGTTAGCACGCACGATGGCTGTTT
ACTCGGAGGTAGAAGGTTCCACTCTGGCTTAAGTATGTTATCCCGTGTTTATAATGAGACTTTC
TGCAACCTTCTTAAGTGGAGGTGCCTGTCCCCAGGCCATGTATGTTGGCTTTTTAAGCCTCTTA
AGAAGTGGATTACCTGCCAACTACTGAAGCTTTGTGGAGACACCAGTCAGAAGAGGGGAAACCA
TCCAACTTGGATTTCCTGCCCCCAGCGATGGATGGGTGGCTTGACTACTCAGTGTGGTGTCGGT
CTCTGAGCTGAAGAACCGTTTCTTTGTTCTTTGGTCCCTTTCTTGATTGAGTGGTCGCATGTCA
CGCTGCATAGCAACCAGTCTCTGAGACCCCGAGTCTGTACCCCGGCACCTTTGCAATTATGTCC
CCCAGTATAACCCACCTCTGTCCCAGCCAGCTACCTTTCTAGCCAAGACAGATTCGCGGTATCT
TTTTTTCCCCAATTGAGATTTACAGTTTGTAAATTTGTGTACATTTCCTAATTTCATGAACAGG
TAAAATAGTAACCAGGCCTCAGTTTGCTAGTGGGAGTTTTTAAGTCCGTGACTAGTATGTCTTG
AAGCCTTGCTACAGCCCTGTGGCCTGTCACTTCTCAGACGTGCAGTCAGTTGACCCATAGTGTG
GAACCGGGCGCAGCTGGGCACGGCCTTCCAAGAAGAGTTAAAATTGCTGGTTTAAGTACAGACT
TTAGAACTAAATGGAAGAGCAAAGAAGGAAAATTATATTTTTAACAAAAGAGAATATTCAGGCT
TTATTTCTGGTATGAAATTTATATTTTTAAAGAATATATATCCTATATTATCACACCGGAGACT
TTAGATTCCTTTCTGGTTACAGACATTGCTGGTAGTTGGATTCTATTTTTATTGTATTCATTTA
TTTCTCTTAGGGGGAAAATTGTAAAGAAACAAAGATTCCGGATGAATGTATCCTAGAAATAAAA
GTTGAGAGATTCTTA

hide sequence

RefSeq Acc Id:

XM_006243997 ⟹ XP_006244059

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	122,469,223 - 122,524,861 (-)	NCBI
mRatBN7.2	8	113,590,998 - 113,646,795 (-)	NCBI
Rnor_6.0	8	121,916,233 - 121,973,140 (-)	NCBI
Rnor_5.0	8	121,231,793 - 121,287,105 (-)	NCBI

Sequence:

show sequence

TCCAAGCGCTGGCGGCCCAGTCCGTCGGCCCGTCGGTCCGCTCGTCCGCTGCCGGTGCCGAGCG
CGCCTAGGCCGTCGTCGCTGTCCCTTCGTCTGTCCGGCCCGAAGCGGCGGCCGGGCGCTCACCA
TGGCGTCGTTCATCTGGGTGCAGCTGAAGAAGACCTCGGAGGTGGACCTGGCCAAGCCGCTGGT
CAAGTTCATCCAGCAGACGTACCCGAGCGGCGGCGAGGAGCAGGCCCAGTACTGCCGCGCGGCC
GAGGAGCTCAGCAAGCTGCGGCGCTCGGCGCTCGGCCGCCCGCTGGACAAGCACGAGGGCGCGC
TGGAGACGCTGCTGAGATATTATGACCAGATTTGTTCTATTGAACCCAAGTTCCCATTTTCTGA
AAATCAGATCTGCTTGACATTTACGTGGAAGGATGCTTTTGATAAAGGTTCCCTTTTTGGAGGA
TCTGTAAAATTGGCTCTTGCAAGCTTAGGATATGAAAAGAGCTGTGTGTTGTTCAACTGTGCTG
CCTTAGCTAGCCAGATCGCAGCAGAGCAGAACCTGGATAATGATGAAGGACTGAAAACCGCTGC
TAAGCAGTACCAGTTTGCTAGTGGTGCCTTTTTACATATTAAAGACACAGTTTTATCTGCCTTA
AGTCGAGAGCCTACTGTGGACATATCTCCAGATACTGTGGGGACCCTCAGTCTTATTATGCTGG
CCCAAGCTCAAGAAGTATTTTTCTTAAAAGCCACAAGAGATAAGATGAAGGATGCCATCATAGC
GAAGCTGGCCAATCAGGCTGCCGATTACTTTGGCGATGCTTTCAAACAGTGTCAGTACAAAGAT
GCCCTCCCCAAGTATTTTTATTTCCAGGAGGTATTCCCTACCCTGGCTGCAAAGCAGTGCATCA
TGCAGGCTAATGCTGAGTACCACCAGTCCATCCTGGCCAAGCAGCAGAAGAAGTTTGGGGAAGA
GATCGCAAGGTTGCAGCATGCAGCAGAACTGATTAAGAATGTGGCCTCTCGCTATGATGAATAT
GTCAATGTGAAGGATTTTTCTGACAAAATCAACCGTGCCCTGGCTGCAGCAAAGAAGGATAATG
ATTTTATTTATCATGACCGTGTTCCGGACCTTAAGGATCTGGATCCTATTGGCAAAGCCACGCT
TGTGAAACCCACTCCAGTTAATGTACCCATCAGCCAGAAGTTCACGGATTTGTTTGAGAAGATG
GTGCCTGTGTCTGTGCAGCAGTCCCTGGCTGTGTTTAGTCAGAGGAAAGCTGACTTGGTTAACA
GATCAATCGCTCAGATGAGAGAAGCTACAACTTTGGCAAATGGAGTACTGGCTTCCCTTAACCT
TCCAGCAGCAATTGAAGATGTGTCTGGAGACACTGTACCTCAGTCTATACTTACCAAGTCCACA
GCTGTAGTCGAGCAGGGAGGCATCCAGACTGTCGACCAGCTGATAAAAGAGCTGCCTGAGCTGC
TACAAAGAAATAGGGAAATATTAGAGGAGTCACTAAGATTGTTGGATGAAGAAGAAGCAACTGA
TAATGACTTAAGAGCAAAATTCAAGGACCGGTGGCAAAGGACTCCATCCAATGACCTGTACAAG
CCTTTACGAGCAGAGGGAGCCAAGTTCAGAGCCGTTTTAGATAAAGCGGTGCAAGCGGATGGAC
AGGTGAAGGAGCGCTACCAGTCCCACCGAGACACCATCGCCCTTCTGTGTAAGCCAGAGCCGGA
GCTGAATGCCGCCATCCCTTCTGCTAACCCAGCAAAGACCATGCAGGGCAGTGAGGTTGTAAAT
GTCTTAAAATCCTTATTATCAAATCTTGATGAAATAAAGAAGGAAAGAGAGGGTCTTGAGAATG
ACCTGAAGTCAGTGAATTTTGACATGACAAGCAAGTTTTTGACAGCTCTGGCCCAAGATGGCGT
GATAAATGAGGAGGCTCTTTCTGTCACTGAGCTGGATCGGATCTATGGTGGGCTAACAACTAAA
GTTCAAGAGTCTCTGAAGAAACAGGAGGGACTTCTAAAAAATATACAGGTCTCACACCAGGAAT
TCTCCAAAATGAAGCAGTCTAACAGTGAGGCCAGCCTGAGGGAAGAGGTCCTGAAGAACTTAGC
GACCGCGTACGACAACTTCGTGGAGCTCGTAGCTAACTTGAAAGAGGGCACAAAGTTTTACAAT
GAGCTGACTGAAATCCTGGTCAGGTTCCAGAACAAATGCAGTGACATAGTGTTTGCACGGAAGA
CGGAAAGAGATGAGCTCTTGAAGGATCTGCAGCAGAGCATTGCCAGAGAGCCCAGCGCTCCTTC
TATCCCTCCGCCAGCATATCAGTCCTCCCCAGCAGGGGGACATGCGACAGCTCCAACTCCAGCT
CCAAGAACCATGCCGCCTGCTAAGCCCCAGCCTCCAGCCCGGCCTCCACCTCCTGTGCTTCCTG
CAAACCGAGTTCCTCCTGCTGCTGCCGCTACTGCCCCTGCAGGGGTGGGGACTGCTTCAGCAGC
ACCGCCACAGACCCCTGGCTCTGCTCCCCCTCCACAGGCTCAGGGACCACCGTATCCCACCTAT
CCAGGATATCCCGGGTATTGCCAAATGCCCATGCCCATGGGCTACAACCCCTACACATATGGCC
AGTACAATATGCCGTACCCACCGGTGTATCACCAGAGCCCTGGACAGGCTCCGTACCCAGGACC
CCAGCAGCCTACCTACCCCTTCCCTCAGCCCCCGCAGCAGTCATACTATCCACAGCAGTAATGC
CACCACGCGCTGCTGGTTCAGATCAGAGCGACAGGACAGCGGCTGCCACCACGCTCTAAGCCAC
ACTCTGGCCACTCGAGAATATCTCGCTCTCCTGATGCCTGTGGATGATTTCTGTCTGTGGATAA
AACCGAAGGCTGGGCCCCACCTCCACATTTGATCGCACTTGTGAGATTCTGCTGCTGTTGCAGC
ATAAACGCTAGCTATGATAGCAATGGAAAAAATTACAGTTCCATAAAACGCTGAAAATGACAAT
TAAACCTGCAAGTGAAACCTTTGAAATTAGCATACTTTATAAGATGAGGTTGGGACAAGGATGG
CTTAAATACTGATATTTAAGGAAAAAGTTTTCTTTCTCTTGGTTTATTGATTTAGTTTAATTTC
TATTATGATATTTTGCATAATCAAGGCATTGTAAATCTTATAATTTAAAAATAAATTACTTACG
AACAGTTGTCATTGTTATGGTTTGTCCTTGATTCTCATTGCTGTCTGATTCCTTTCTGGTGTTA
GCCTCTCCTTTGTATGTTCACAGGCTCCGTGTACTGTGTTGGACTGCATGGACTGCAGACTGGC
AGTCAGGTGAGGGCTGCCCTGAGAGCCCAAGCGCACCAGCTTGTCTGCCATACTCTCCTTAGTC
AGTCCTGTTGACACTGATTTTTAAAAGTCCTATAATGTGGGAGACACACACAATTGTTACCAAA
GATTCTTCAAATAAATATAAAATTTAAAAGTATGTATTTAATGTTTTATTATTAGATTTTCCAA
GAAAATGATGCAAATTCTGGTAATAATTCACTTCCCTTACCCATAATCCGGTCAAAGTGAGTAG
TTTTAGCCGTACAGTGCCAGGATGTGTAGAGCCTGGCGAAAGCTCCTGTGCCTTTCTCGTCCTT
GGCTCCATCTACTCTTGTCCTGTGATGGTGACTGTGCGCAGTGTACTGGAACAGATCTTCTTAA
CCCTTCTTTTCAAATTTCATATTATGATTTTTTATTTTCTGTGGTTCCTGGAAGCTGAGGTTAT
TCTGTAATCCAGGAGCATGTAAGACAATTGGTGGGGCTGCGTGCAAGCCCCAAACAGTGAGGTC
TCGGGGGCTCTGCCTGTGCGAGGCTCTTGTCCAACAGAACAGGCGTACAGACAGATTTCCTAAT
CTGTGTTTGTCTTCTAAGTTTAATGCTGACATCTTGTTTCTCATCTCGTTTAAATGATACTGTC
ACTTAGTCCTCATTGCTCTCAATGACAATTCAGGCTGATACTTTCAAATGTAAGACTGAAGATA
CGATTGTACAAGGGAGTAAACTGGTTTAAATGTGTGTATTTAAAGCTCCGTGCTTTGTTGTATG
CAGAAAACACAGACCAATCGCCGGGAATGTGGACATTGGCTTAAACCTCGACAAAACGTAACAA
ACGTGCCATTGCTCAGCTCCGTGCTCCGCGGTACTCGGTGTATGAGACAGTGTATTTGAATCCT
CTGTAAATGCATTTGAATTTTATATTCTCCCCTCCTGAGTTCTTATACTGACACGAGACATCCC
CCGAGTTAGGGAGCTCCCAGACTGCTAGTGTATTCCTTACTAATGCAAAACAACCACCAAAAGA
AAAAAATAGAAAAAAGAAAAAAAAAGTGGCCTGAATATTCTCTTGGGGAAAGGGGGTTGGAGGT
CTAACGGGAAGGGCAAGTGCATCAGAGAGCCAAAGGGAGGAGGGGTCAGGCCGGCGGCCATTTC
CTCCTGCCCTGTGCTATGCTTCCAGGCTCACAGCGGACAGTCAGCGGGGGAGGGCCCCTTCCAG
TTGCCTCCCAGCTCAGCTCCTGAGGGAAGCCTCTTGCCAGGTGTCTCCCCCTTCACGCTGCTCA
GGATGCTCCGGTCTCGGGTCAGGTGCCCTTACCCTGCAGCGCCAACTTTGCCTTCCTAGGCCTG
TTCGGTTTGCTGGCCGGAAGCCTCCTCATGCGCCTGTTGTCTAGATGGCGTCCCTCACCATCAG
CACACCCTAACTGTGCTCCGTTGGCTGTGCTCTTTAGAACACACTGCAGAAGTTAGCACGCACG
ATGGCTGTTTACTCGGAGGTAGAAGGTTCCACTCTGGCTTAAGTATGTTATCCCGTGTTTATAA
TGAGACTTTCTGCAACCTTCTTAAGTGGAGGTGCCTGTCCCCAGGCCATGTATGTTGGCTTTTT
AAGCCTCTTAAGAAGTGGATTACCTGCCAACTACTGAAGCTTTGTGGAGACACCAGTCAGAAGA
GGGGAAACCATCCAACTTGGATTTCCTGCCCCCAGCGATGGATGGGTGGCTTGACTACTCAGTG
TGGTGTCGGTCTCTGAGCTGAAGAACCGTTTCTTTGTTCTTTGGTCCCTTTCTTGATTGAGTGG
TCGCATGTCACGCTGCATAGCAACCAGTCTCTGAGACCCCGAGTCTGTACCCCGGCACCTTTGC
AATTATGTCCCCCAGTATAACCCACCTCTGTCCCAGCCAGCTACCTTTCTAGCCAAGACAGATT
CGCGGTATCTTTTTTTCCCCAATTGAGATTTACAGTTTGTAAATTTGTGTACATTTCCTAATTT
CATGAACAGGTAAAATAGTAACCAGGCCTCAGTTTGCTAGTGGGAGTTTTTAAGTCCGTGACTA
GTATGTCTTGAAGCCTTGCTACAGCCCTGTGGCCTGTCACTTCTCAGACGTGCAGTCAGTTGAC
CCATAGTGTGGAACCGGGCGCAGCTGGGCACGGCCTTCCAAGAAGAGTTAAAATTGCTGGTTTA
AGTACAGACTTTAGAACTAAATGGAAGAGCAAAGAAGGAAAATTATATTTTTAACAAAAGAGAA
TATTCAGGCTTTATTTCTGGTATGAAATTTATATTTTTAAAGAATATATATCCTATATTATCAC
ACCGGAGACTTTAGATTCCTTTCTGGTTACAGACATTGCTGGTAGTTGGATTCTATTTTTATTG
TATTCATTTATTTCTCTTAGGGGGAAAATTGTAAAGAAACAAAGATTCCGGATGAATGTATCCT
AGAAATAAAAGTTGAGAGATTCTTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001025081	(Get FASTA)	NCBI Sequence Viewer
	XP_006244059	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF07179	(Get FASTA)	NCBI Sequence Viewer
	EDL77006	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000012114
	ENSRNOP00000012114.8
GenBank Protein	Q9QZA2	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001025081 ⟸ NM_001029910

- UniProtKB:

A0A140TAA4 (UniProtKB/TrEMBL), A6I3M1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASFIWVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRSALGRPLDKHEGA
LETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCA
ALASQIAAEQNLDNDEGLKTAAKQYQFASGAFLHIKDTVLSALSREPTVDISPDTVGTLSLIML
AQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDALPKEVFPTLAAKQCIMQANA
EYHQSILAKQQKKFGEEIARLQHAAELIKNVASRYDEYVNVKDFSDKINRALAAAKKDNDFIYH
DRVPDLKDLDPIGKATLVKPTPVNVPISQKFTDLFEKMVPVSVQQSLAVFSQRKADLVNRSIAQ
MREATTLANGVLASLNLPAAIEDVSGDTVPQSILTKSTAVVEQGGIQTVDQLIKELPELLQRNR
EILEESLRLLDEEEATDNDLRAKFKDRWQRTPSNDLYKPLRAEGAKFRAVLDKAVQADGQVKER
YQSHRDTIALLCKPEPELNAAIPSANPAKTMQGSEVVNVLKSLLSNLDEIKKEREGLENDLKSV
NFDMTSKFLTALAQDGVINEEALSVTELDRIYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMK
QSNSEASLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDE
LLKDLQQSIAREPSAPSIPPPAYQSSPAGGHATAPTPAPRTMPPAKPQPPARPPPPVLPANRVP
PAAAATAPAGVGTASAAPPQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYTYGQYNMP
YPPVYHQSPGQAPYPGPQQPTYPFPQPPQQSYYPQQ

hide sequence

RefSeq Acc Id:	XP_006244059 ⟸ XM_006243997
- Peptide Label:	isoform X1
- UniProtKB:	Q9QZA2 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MASFIWVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRSALGRPLDKHEGA LETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCA ALASQIAAEQNLDNDEGLKTAAKQYQFASGAFLHIKDTVLSALSREPTVDISPDTVGTLSLIML AQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDALPKYFYFQEVFPTLAAKQCI MQANAEYHQSILAKQQKKFGEEIARLQHAAELIKNVASRYDEYVNVKDFSDKINRALAAAKKDN DFIYHDRVPDLKDLDPIGKATLVKPTPVNVPISQKFTDLFEKMVPVSVQQSLAVFSQRKADLVN RSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQSILTKSTAVVEQGGIQTVDQLIKELPEL LQRNREILEESLRLLDEEEATDNDLRAKFKDRWQRTPSNDLYKPLRAEGAKFRAVLDKAVQADG QVKERYQSHRDTIALLCKPEPELNAAIPSANPAKTMQGSEVVNVLKSLLSNLDEIKKEREGLEN DLKSVNFDMTSKFLTALAQDGVINEEALSVTELDRIYGGLTTKVQESLKKQEGLLKNIQVSHQE FSKMKQSNSEASLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARK TERDELLKDLQQSIAREPSAPSIPPPAYQSSPAGGHATAPTPAPRTMPPAKPQPPARPPPPVLP ANRVPPAAAATAPAGVGTASAAPPQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYTYG QYNMPYPPVYHQSPGQAPYPGPQQPTYPFPQPPQQSYYPQQ hide sequence

Ensembl Acc Id:

ENSRNOP00000012114 ⟸ ENSRNOT00000012114

Protein Domains

BRO1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9QZA2-F1-model_v2	AlphaFold	Q9QZA2	1-873	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696348

Promoter ID:

EPDNEW_R6872

Type:

initiation region

Name:

Pdcd6ip_1

Description:

programmed cell death 6 interacting protein

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	8	121,973,122 - 121,973,182	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:68357	AgrOrtholog
BioCyc Gene	G2FUF-28947	BioCyc
Ensembl Genes	ENSRNOG00000008981	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000012114	ENTREZGENE
	ENSRNOT00000012114.8	UniProtKB/Swiss-Prot
Gene3D-CATH	1.25.40.280	UniProtKB/Swiss-Prot
	alix/aip1 in complex with the ypdl late domain	UniProtKB/Swiss-Prot
	alix/aip1 like domains	UniProtKB/Swiss-Prot
InterPro	ALIX_V_dom	UniProtKB/Swiss-Prot
	BRO1_dom	UniProtKB/Swiss-Prot
	BRO1_sf	UniProtKB/Swiss-Prot
NCBI Gene	Pdcd6ip	ENTREZGENE
PANTHER	PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN	UniProtKB/Swiss-Prot
	PTHR23030	UniProtKB/Swiss-Prot
Pfam	ALIX_LYPXL_bnd	UniProtKB/Swiss-Prot
	BRO1	UniProtKB/Swiss-Prot
PhenoGen	Pdcd6ip	PhenoGen
PROSITE	BRO1	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000008981	RatGTEx
SMART	BRO1	UniProtKB/Swiss-Prot
TIGR	TC229010
UniProt	A0A140TAA4	ENTREZGENE, UniProtKB/TrEMBL
	A6I3M1	ENTREZGENE, UniProtKB/TrEMBL
	PDC6I_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Pdcd6ip	programmed cell death 6 interacting protein			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)