Ric8b (RIC8 guanine nucleotide exchange factor B) - Rat Genome Database

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Pathways
Gene: Ric8b (RIC8 guanine nucleotide exchange factor B) Rattus norvegicus
Analyze
Symbol: Ric8b
Name: RIC8 guanine nucleotide exchange factor B
RGD ID: 631419
Description: Predicted to enable G-protein alpha-subunit binding activity; guanyl-nucleotide exchange factor activity; and protein folding chaperone. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to act upstream of or within regulation of G protein-coupled receptor signaling pathway. Predicted to be located in cytosol. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human RIC8B (RIC8 guanine nucleotide exchange factor B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: chaperone Ric-8B; heterotrimeric G protein guanine nucleotide exchange factor-like protein Ric-8B; resistance to inhibitors of cholinesterase 8 homolog B; resistance to inhibitors of cholinesterase 8 homolog B (C. elegans); resistance to inhibitors of cholinesterase 8B; resistance to inhibitors of cholinesterase 8B (C. elegans); synembryn-B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8720,636,337 - 20,730,066 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl720,636,687 - 20,730,178 (-)EnsemblGRCr8
mRatBN7.2718,746,716 - 18,843,264 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl718,748,641 - 18,842,372 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx720,710,861 - 20,803,310 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0722,873,544 - 22,965,991 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0722,650,520 - 22,742,965 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0725,919,266 - 26,015,506 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl725,919,867 - 26,012,344 (+)Ensemblrn6Rnor6.0
Rnor_5.0726,049,060 - 26,145,319 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4720,871,670 - 20,965,053 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera715,965,495 - 16,057,891 (-)NCBICelera
RGSC_v3.1720,891,940 - 20,985,324 (-)NCBI
Cytogenetic Map7q13NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell cortex  (IEA)
cytoplasm  (IBA,IEA)
cytosol  (IEA,ISO)
plasma membrane  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor. Tall GG, etal., J Biol Chem 2003 Mar 7;278(10):8356-62.
Additional References at PubMed
PMID:12652642   PMID:21467038   PMID:24585571   PMID:26966186  


Genomics

Comparative Map Data
Ric8b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8720,636,337 - 20,730,066 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl720,636,687 - 20,730,178 (-)EnsemblGRCr8
mRatBN7.2718,746,716 - 18,843,264 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl718,748,641 - 18,842,372 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx720,710,861 - 20,803,310 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0722,873,544 - 22,965,991 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0722,650,520 - 22,742,965 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0725,919,266 - 26,015,506 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl725,919,867 - 26,012,344 (+)Ensemblrn6Rnor6.0
Rnor_5.0726,049,060 - 26,145,319 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4720,871,670 - 20,965,053 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera715,965,495 - 16,057,891 (-)NCBICelera
RGSC_v3.1720,891,940 - 20,985,324 (-)NCBI
Cytogenetic Map7q13NCBI
RIC8B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812106,774,682 - 106,889,316 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12106,774,621 - 106,889,316 (+)Ensemblhg38GRCh38
GRCh3712107,168,460 - 107,283,094 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612105,692,529 - 105,807,224 (+)NCBIBuild 36Build 36hg18NCBI36
Celera12106,833,992 - 106,948,676 (+)NCBICelera
Cytogenetic Map12q23.3NCBI
HuRef12104,228,794 - 104,343,508 (+)NCBIHuRef
CHM1_112107,134,243 - 107,248,934 (+)NCBICHM1_1
T2T-CHM13v2.012106,738,328 - 106,852,950 (+)NCBIT2T-CHM13v2.0
Ric8b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391084,753,136 - 84,854,201 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1084,753,480 - 84,854,201 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381084,917,268 - 85,018,337 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1084,917,616 - 85,018,337 (+)Ensemblmm10GRCm38
MGSCv371084,380,361 - 84,479,192 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361084,347,415 - 84,446,246 (+)NCBIMGSCv36mm8
Celera1086,895,399 - 86,994,277 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1041.63NCBI
Ric8b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540540,659,953 - 40,783,150 (+)Ensembl
ChiLan1.0NW_00495540540,659,946 - 40,782,870 (+)NCBIChiLan1.0ChiLan1.0
RIC8B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210114,825,588 - 114,943,155 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112114,827,068 - 114,939,552 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012104,341,903 - 104,456,784 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112107,736,090 - 107,850,798 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12107,736,090 - 107,850,789 (+)EnsemblpanPan2panpan1.1
RIC8B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11031,883,764 - 31,982,622 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1031,885,041 - 31,982,514 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1031,868,394 - 31,886,606 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01032,724,734 - 32,824,108 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1032,722,675 - 32,823,740 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11032,460,815 - 32,560,165 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01032,750,948 - 32,850,235 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01032,937,322 - 33,036,409 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ric8b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494515,073,076 - 15,180,621 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364928,081,701 - 8,190,698 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364928,081,821 - 8,190,681 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RIC8B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl513,468,937 - 13,580,164 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1513,468,933 - 13,580,497 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2513,323,854 - 13,432,521 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RIC8B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111101,983,459 - 102,100,478 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11101,982,872 - 102,087,627 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037142,947,740 - 143,065,274 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ric8b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247502,600,383 - 2,712,113 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247502,600,465 - 2,712,120 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ric8b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11163,432,258 - 163,526,725 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ric8b
1082 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:29
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000009625
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71746044762460447Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)72005723265057232Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat

Markers in Region
RH138502  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2718,758,590 - 18,758,772 (-)MAPPERmRatBN7.2
Rnor_6.0726,003,450 - 26,003,631NCBIRnor6.0
Rnor_5.0726,133,263 - 26,133,444UniSTSRnor5.0
RGSC_v3.4720,880,383 - 20,880,564UniSTSRGSC3.4
Celera715,974,208 - 15,974,389UniSTS
Cytogenetic Map7q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001437970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_175598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005486614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005486616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005486617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005486618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005486620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_593293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_593294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY177755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000009625   ⟹   ENSRNOP00000009625
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl720,644,018 - 20,730,066 (-)Ensembl
mRatBN7.2 Ensembl718,748,659 - 18,842,372 (-)Ensembl
Rnor_6.0 Ensembl725,919,867 - 26,012,344 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090153   ⟹   ENSRNOP00000069306
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl720,636,687 - 20,730,066 (-)Ensembl
mRatBN7.2 Ensembl718,748,642 - 18,842,347 (-)Ensembl
Rnor_6.0 Ensembl725,919,871 - 26,002,326 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093769   ⟹   ENSRNOP00000082457
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl720,647,748 - 20,730,066 (-)Ensembl
mRatBN7.2 Ensembl718,748,642 - 18,842,347 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098436   ⟹   ENSRNOP00000089623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl720,637,578 - 20,730,066 (-)Ensembl
mRatBN7.2 Ensembl718,748,659 - 18,842,372 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103484   ⟹   ENSRNOP00000076678
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl720,644,018 - 20,730,066 (-)Ensembl
mRatBN7.2 Ensembl718,748,641 - 18,842,347 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000173351   ⟹   ENSRNOP00000103079
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl720,637,578 - 20,730,178 (-)Ensembl
RefSeq Acc Id: NM_175598   ⟹   NP_783188
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8720,637,578 - 20,730,066 (-)NCBI
mRatBN7.2718,749,878 - 18,842,368 (-)NCBI
Rnor_6.0725,919,867 - 26,012,344 (+)NCBI
Rnor_5.0726,049,060 - 26,145,319 (+)NCBI
RGSC_v3.4720,871,670 - 20,965,053 (-)RGD
Celera715,965,495 - 16,057,891 (-)RGD
Sequence:
RefSeq Acc Id: XM_006241180   ⟹   XP_006241242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8720,636,337 - 20,730,031 (-)NCBI
mRatBN7.2718,746,716 - 18,843,264 (-)NCBI
Rnor_6.0725,919,268 - 26,015,506 (+)NCBI
Rnor_5.0726,049,060 - 26,145,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006241182   ⟹   XP_006241244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8720,636,337 - 20,730,031 (-)NCBI
mRatBN7.2718,746,716 - 18,843,264 (-)NCBI
Rnor_6.0725,919,266 - 26,015,506 (+)NCBI
Rnor_5.0726,049,060 - 26,145,319 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594824   ⟹   XP_017450313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8720,637,664 - 20,730,031 (-)NCBI
mRatBN7.2718,746,716 - 18,842,378 (-)NCBI
Rnor_6.0725,919,267 - 26,012,208 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063263436   ⟹   XP_063119506
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8720,636,337 - 20,730,031 (-)NCBI
RefSeq Acc Id: XR_005486614
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8720,641,518 - 20,730,031 (-)NCBI
mRatBN7.2718,750,397 - 18,842,378 (-)NCBI
RefSeq Acc Id: XR_005486616
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8720,637,815 - 20,730,031 (-)NCBI
mRatBN7.2718,750,397 - 18,842,378 (-)NCBI
RefSeq Acc Id: XR_005486617
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8720,637,661 - 20,730,031 (-)NCBI
mRatBN7.2718,746,716 - 18,842,378 (-)NCBI
RefSeq Acc Id: XR_005486618
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8720,637,663 - 20,730,031 (-)NCBI
mRatBN7.2718,746,716 - 18,842,378 (-)NCBI
RefSeq Acc Id: XR_005486620
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8720,641,518 - 20,730,031 (-)NCBI
mRatBN7.2718,750,397 - 18,842,378 (-)NCBI
RefSeq Acc Id: XR_010052969
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8720,636,337 - 20,730,031 (-)NCBI
RefSeq Acc Id: NP_783188   ⟸   NM_175598
- UniProtKB: Q80ZG0 (UniProtKB/Swiss-Prot),   A6IFE7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241244   ⟸   XM_006241182
- Peptide Label: isoform X3
- UniProtKB: A0A8I5Y0A0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241242   ⟸   XM_006241180
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017450313   ⟸   XM_017594824
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G7F7 (UniProtKB/TrEMBL),   A0A8I5Y0A0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069306   ⟸   ENSRNOT00000090153
Ensembl Acc Id: ENSRNOP00000009625   ⟸   ENSRNOT00000009625
Ensembl Acc Id: ENSRNOP00000089623   ⟸   ENSRNOT00000098436
Ensembl Acc Id: ENSRNOP00000076678   ⟸   ENSRNOT00000103484
Ensembl Acc Id: ENSRNOP00000082457   ⟸   ENSRNOT00000093769
RefSeq Acc Id: XP_063119506   ⟸   XM_063263436
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000103079   ⟸   ENSRNOT00000173351

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80ZG0-F1-model_v2 AlphaFold Q80ZG0 1-520 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695103
Promoter ID:EPDNEW_R5628
Type:single initiation site
Name:Ric8b_1
Description:RIC8 guanine nucleotide exchange factor B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0725,919,813 - 25,919,873EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631419 AgrOrtholog
BioCyc Gene G2FUF-34624 BioCyc
Ensembl Genes ENSRNOG00000007323 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000009625.6 UniProtKB/Swiss-Prot
  ENSRNOT00000090153 ENTREZGENE
  ENSRNOT00000093769 ENTREZGENE
  ENSRNOT00000098436 ENTREZGENE
  ENSRNOT00000173351 ENTREZGENE
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot
InterPro ARM-like UniProtKB/Swiss-Prot
  ARM-type_fold UniProtKB/Swiss-Prot
  Gua_nucleotide_exch_fac_Ric8 UniProtKB/Swiss-Prot
  Synembryn UniProtKB/Swiss-Prot
KEGG Report rno:314681 UniProtKB/Swiss-Prot
NCBI Gene 314681 ENTREZGENE
PANTHER PTHR12425 UniProtKB/Swiss-Prot
  SYNEMBRYN-B UniProtKB/Swiss-Prot
Pfam Ric8 UniProtKB/Swiss-Prot
PhenoGen Ric8b PhenoGen
PRINTS SYNEMBRYN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007323 RatGTEx
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot
UniProt A0A0G2JV09 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y0A0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G7F7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GI93 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LEJ7_RAT UniProtKB/TrEMBL
  A6IFE7 ENTREZGENE, UniProtKB/TrEMBL
  A6IFE8 ENTREZGENE, UniProtKB/TrEMBL
  Q80ZG0 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-09-18 Ric8b  RIC8 guanine nucleotide exchange factor B  Ric8b  resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Ric8b  resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)    resistance to inhibitors of cholinesterase 8B (C. elegans)  Name updated 1299863 APPROVED
2004-02-11 E3sp  resistance to inhibitors of cholinesterase 8B (C. elegans)  Ric8b  heterotrimeric G protein guanine nucleotide exchange factor-like protein Ric-8B  Name updated 625702 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_homology homolog of C. elegans Ric-8 633903