Itpkc (inositol-trisphosphate 3-kinase C) - Rat Genome Database

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Gene: Itpkc (inositol-trisphosphate 3-kinase C) Rattus norvegicus
Analyze
Symbol: Itpkc
Name: inositol-trisphosphate 3-kinase C
RGD ID: 631336
Description: Enables kinase activity. Predicted to be involved in cellular response to calcium ion; inositol phosphate biosynthetic process; and phosphatidylinositol phosphate biosynthetic process. Predicted to be located in nuclear speck. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human ITPKC (inositol-trisphosphate 3-kinase C); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; allethrin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: inositol 1,4,5-trisphosphate 3-kinase C; insP 3-kinase C; IP3 3-kinase C; IP3K C; IP3K-C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8191,628,606 - 91,650,182 (-)NCBIGRCr8
mRatBN7.2182,500,957 - 82,522,533 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl182,500,957 - 82,522,779 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx187,904,062 - 87,925,518 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0196,390,711 - 96,412,265 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0189,659,928 - 89,681,384 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0184,018,857 - 84,040,433 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl184,018,859 - 84,040,433 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0185,229,796 - 85,251,373 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4182,284,846 - 82,306,422 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1182,362,958 - 82,384,779 (-)NCBI
Celera176,913,801 - 76,935,408 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISO,ISS)
nuclear speck  (IEA,ISO)
nucleus  (IBA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Rat inositol 1,4,5-trisphosphate 3-kinase C is enzymatically specialized for basal cellular inositol trisphosphate phosphorylation and shuttles actively between nucleus and cytoplasm. Nalaskowski MM, etal., J Biol Chem 2003 May 30;278(22):19765-76.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Immune-related genes STIM1, ITPKC and PELI1 polymorphisms are associated with risk of colorectal cancer. Zhu L, etal., Eur J Cancer Prev. 2021 Sep 1;30(5):357-363. doi: 10.1097/CEJ.0000000000000641.
Additional References at PubMed
PMID:14517551  


Genomics

Comparative Map Data
Itpkc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8191,628,606 - 91,650,182 (-)NCBIGRCr8
mRatBN7.2182,500,957 - 82,522,533 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl182,500,957 - 82,522,779 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx187,904,062 - 87,925,518 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0196,390,711 - 96,412,265 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0189,659,928 - 89,681,384 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0184,018,857 - 84,040,433 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl184,018,859 - 84,040,433 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0185,229,796 - 85,251,373 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4182,284,846 - 82,306,422 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1182,362,958 - 82,384,779 (-)NCBI
Celera176,913,801 - 76,935,408 (-)NCBICelera
Cytogenetic Map1q21NCBI
ITPKC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381940,717,112 - 40,740,860 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1940,717,112 - 40,740,860 (+)EnsemblGRCh38hg38GRCh38
GRCh371941,223,017 - 41,246,765 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361945,914,848 - 45,938,605 (+)NCBINCBI36Build 36hg18NCBI36
Build 341945,914,847 - 45,938,603NCBI
Celera1938,023,433 - 38,047,190 (+)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1937,656,377 - 37,680,128 (+)NCBIHuRef
CHM1_11941,222,687 - 41,246,445 (+)NCBICHM1_1
T2T-CHM13v2.01943,537,804 - 43,561,551 (+)NCBIT2T-CHM13v2.0
Itpkc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39726,906,595 - 26,928,042 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl726,906,597 - 26,928,086 (-)EnsemblGRCm39 Ensembl
GRCm38727,207,170 - 27,228,617 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl727,207,172 - 27,228,661 (-)EnsemblGRCm38mm10GRCm38
MGSCv37727,992,189 - 28,013,616 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36726,915,930 - 26,937,357 (-)NCBIMGSCv36mm8
Celera721,784,090 - 21,805,517 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map715.85NCBI
Itpkc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955578598,351 - 614,081 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955578597,105 - 614,081 (-)NCBIChiLan1.0ChiLan1.0
ITPKC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22046,976,610 - 46,999,354 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11948,846,416 - 48,870,305 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01937,761,221 - 37,785,118 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11946,267,598 - 46,292,236 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1946,267,754 - 46,290,935 (+)Ensemblpanpan1.1panPan2
ITPKC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11113,037,833 - 113,053,877 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1113,039,093 - 113,053,738 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1112,440,273 - 112,456,324 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01113,636,482 - 113,652,541 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1113,636,486 - 113,652,393 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11113,196,051 - 113,212,102 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01112,827,654 - 112,843,748 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01113,821,972 - 113,838,031 (-)NCBIUU_Cfam_GSD_1.0
Itpkc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934914,578,574 - 14,594,784 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366613,006,505 - 3,022,823 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366613,006,506 - 3,023,355 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITPKC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl648,943,357 - 48,961,438 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1648,943,207 - 48,962,101 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2644,627,778 - 44,646,058 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Itpkc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624925645,385 - 662,580 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624925645,528 - 663,768 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Itpkc
131 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:343
Count of miRNA genes:194
Interacting mature miRNAs:239
Transcripts:ENSRNOT00000018696
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)15034351099980958Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17843075491209302Rat

Markers in Region
RH132115  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2182,501,182 - 82,501,364 (+)MAPPERmRatBN7.2
Rnor_6.0184,019,083 - 84,019,264NCBIRnor6.0
Rnor_5.0185,230,022 - 85,230,203UniSTSRnor5.0
RGSC_v3.4182,285,072 - 82,285,253UniSTSRGSC3.4
Celera176,914,027 - 76,914,208UniSTS
RH 3.4 Map1825.7UniSTS
Cytogenetic Map1q21UniSTS
RH142788  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2182,509,682 - 82,509,883 (+)MAPPERmRatBN7.2
Rnor_6.0184,027,583 - 84,027,783NCBIRnor6.0
Rnor_5.0185,238,522 - 85,238,722UniSTSRnor5.0
RGSC_v3.4182,293,572 - 82,293,772UniSTSRGSC3.4
Celera176,922,557 - 76,922,758UniSTS
RH 3.4 Map1827.7UniSTS
Cytogenetic Map1q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000018696   ⟹   ENSRNOP00000018696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl182,500,957 - 82,522,425 (-)Ensembl
Rnor_6.0 Ensembl184,018,859 - 84,040,433 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100648   ⟹   ENSRNOP00000084385
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl182,500,959 - 82,522,779 (-)Ensembl
RefSeq Acc Id: NM_178094   ⟹   NP_835195
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8191,628,606 - 91,650,182 (-)NCBI
mRatBN7.2182,500,957 - 82,522,533 (-)NCBI
Rnor_6.0184,018,857 - 84,040,433 (-)NCBI
Rnor_5.0185,229,796 - 85,251,373 (-)NCBI
RGSC_v3.4182,284,846 - 82,306,422 (-)RGD
Celera176,913,801 - 76,935,408 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_835195 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAO20335 (Get FASTA)   NCBI Sequence Viewer  
  CAD29464 (Get FASTA)   NCBI Sequence Viewer  
  EDM07966 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018696.4
  ENSRNOP00000084385.1
  ENSRNOP00055047858
GenBank Protein Q80ZG2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_835195   ⟸   NM_178094
- UniProtKB: Q80ZG2 (UniProtKB/Swiss-Prot),   A6J9B8 (UniProtKB/TrEMBL),   A0A8L2UJ86 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018696   ⟸   ENSRNOT00000018696
Ensembl Acc Id: ENSRNOP00000084385   ⟸   ENSRNOT00000100648

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80ZG2-F1-model_v2 AlphaFold Q80ZG2 1-678 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689845
Promoter ID:EPDNEW_R370
Type:single initiation site
Name:Itpkc_1
Description:inositol-trisphosphate 3-kinase C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0184,040,349 - 84,040,409EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631336 AgrOrtholog
BioCyc Gene G2FUF-60320 BioCyc
BioCyc Pathway PWY-6361 [1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)] BioCyc
  PWY-6362 [1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)] BioCyc
  PWY-6364 [D-myo-inositol (1,3,4)-trisphosphate biosynthesis] BioCyc
BioCyc Pathway Image PWY-6361 BioCyc
  PWY-6362 BioCyc
  PWY-6364 BioCyc
Ensembl Genes ENSRNOG00000013945 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055033563 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000018696.5 UniProtKB/TrEMBL
  ENSRNOT00000100648.1 UniProtKB/Swiss-Prot
  ENSRNOT00055058018 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.470.160 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro IPK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IPK_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:308451 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 308451 ENTREZGENE
PANTHER INOSITOL-TRISPHOSPHATE 3-KINASE C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12400 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IPK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Itpkc PhenoGen
RatGTEx ENSRNOG00000013945 RatGTEx
  ENSRNOG00055033563 RatGTEx
Superfamily-SCOP SAICAR synthase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2UJ86 ENTREZGENE, UniProtKB/TrEMBL
  A6J9B8 ENTREZGENE, UniProtKB/TrEMBL
  IP3KC_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Itpkc  inositol-trisphosphate 3-kinase C  Itpkc  inositol 1,4,5-trisphosphate 3-kinase C  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-11 Itpkc  inositol 1,4,5-trisphosphate 3-kinase C      Symbol and Name status set to approved 625702 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in heart, brain, and testis with strongest expression in epidermal tissue 633165